@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_1113: (2015-12-21 )
MPVIRVLVMLATMMMKLVKTAKEKKVFKNVGISIMGIAFWEAIKDSIKKQIKKSDWICGNVKTADDYLKTHPNSWFNSAIGVTAITAMLMNVCFADDQSKKEVAQAQKEAENARDRANKSGIELEQEEQKTEQEKQKTEQEKQKTEQEKQKTEQEKQKTEQEKQKTSNIETNNQIKVEQEQQKTEQEKQKTNNTQKDLVNKAEQNCQENHNQFFIKKLGIKAGIAIEIEAECKTPKPTKTNQTPIQPKHLPNSKQPHSQRGSKAQELIAYLQKELESLPYSQKAIAKQVDFYRPSSIAYLELDPRDFNATEEWQKENLKIRSKAQAKMLEMRSLKPDPQAHLSTSQSLLLVQKIFADVSKEIKVVANTEKKVEKAGYGYSKRM
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
P
V
I
R
V
L
V
M
L
A
T
M
M
M
K
L
V
K
T
A
K
E
K
K
V
F
K
N
VGI
S
I
M
G
I
A
F
W
E
A
I
K
D
S
I
K
K
Q
I
K
KSDWICGNVK
T
A
D
D
Y
L
K
TH
P
N
S
W
F
N
SA
I
G
V
T
A
I
T
A
M
L
M
N
V
CFADD
Q
S
K
K
E
V
A
Q
A
Q
K
E
A
E
N
A
RDRANKSGIEL
E
Q
E
E
Q
K
T
E
Q
E
K
Q
K
T
E
Q
E
K
Q
K
T
E
Q
E
K
Q
K
T
E
Q
E
K
Q
K
T
E
Q
E
K
Q
KTSNIETNN
Q
I
K
V
E
Q
E
Q
Q
K
T
E
Q
E
K
Q
KTNN
T
Q
K
D
L
V
N
K
A
E
Q
N
C
Q
E
N
H
N
Q
F
F
I
K
K
LGIKA
G
I
A
I
E
I
E
AECKTPKPTKTNQTPIQPKHLPNSKQP
H
S
QRG
S
K
A
Q
E
L
I
A
Y
L
Q
K
E
L
E
SLPY
S
Q
K
A
I
A
K
Q
V
DFYRPS
S
I
A
Y
L
E
LDPRDFN
A
T
E
E
W
Q
K
EN
L
K
IR
S
K
A
Q
A
K
M
L
E
M
RSLKPD
P
Q
A
HLS
T
S
Q
S
L
L
L
V
Q
K
I
F
A
D
V
S
K
E
I
K
V
V
AN
T
E
K
K
V
E
K
AGYGYSKRM
30
Fugue
79.94
12%
129
- C1 -
3Q8T
-
BECN1_RAT
A:
[172-265]
------------------------------------------------------------------------------------------------
G
S
D
S
E
Q
L
Q
R
E
L
K
E
L
A
L
E
E
E
R
L
I
Q
E
L
E
D
V
E
K
N
R
K
V
V
A
E
N
L
E
K
V
Q
A
E
A
E
R
L
D
Q
E
E
A
Q
Y
Q
R
E
Y
S
E
F
K
R
Q
Q
L
E
L
D
D
E
L
K
S
V
E
N
Q
M
R
Y
A
Q
M
Q
L
D
K
L
K
K
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
78.47
20%
148
- C1 -
1GD2
2
AP1_SCHPO
E:
[5-69]
----------------------------------------------------------------------------------------------
D
Q
E
P
S
S
K
R
K
A
Q
N
R
A
A
Q
R
A
F
R
K
R
K
E
D
H
L
K
A
L
E
T
Q
V
V
T
L
K
E
L
H
S
S
T
T
L
E
N
D
Q
L
R
Q
K
V
R
Q
L
E
E
E
L
R
I
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
Fugue
75.72
13%
122
- C1 -
4QKW
1
MURC_DANRE
A:
[3-103]
------------------------------------------------------------------------------------------------
P
V
S
A
L
S
I
L
S
L
L
E
R
V
S
T
I
I
D
G
V
Q
A
S
Q
Q
R
M
E
E
R
Q
Q
Q
L
E
G
S
V
S
A
V
Q
S
E
L
L
K
L
A
R
D
H
G
A
T
A
T
T
V
D
K
L
L
Q
K
A
R
R
V
S
T
H
V
K
E
V
R
S
R
V
E
K
Q
N
V
R
V
K
K
V
E
T
T
Q
D
E
L
L
T
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
71.93
11%
126
- C1 -
2QA7
-
HIP1_HUMAN
A:
[371-469]
-----------------------------------------------------------------------------------------------------------
D
E
K
D
H
L
I
E
R
L
Y
R
E
I
S
G
L
K
A
Q
L
E
N
M
K
T
E
S
Q
R
V
V
L
Q
L
K
G
H
V
S
E
L
E
A
D
L
A
E
Q
Q
H
L
R
Q
Q
A
A
D
D
C
E
F
L
R
A
E
L
D
E
L
R
R
Q
R
E
D
T
E
K
A
Q
R
S
L
S
E
I
E
R
K
A
Q
A
N
E
Q
R
Y
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
Fugue
67.36
14%
152
- C1 -
1X8Y
-
LMNA_HUMAN
A:
[313-386]
--------------------------------------------------------------------------------------------------------------------
L
A
A
K
E
A
K
L
R
D
L
E
D
S
L
A
R
E
R
D
T
S
R
R
L
L
A
E
K
E
R
E
M
A
E
M
R
A
R
M
Q
Q
Q
L
D
E
Y
Q
E
L
L
D
I
K
L
A
L
D
M
E
I
H
A
Y
R
K
L
L
E
G
E
E
E
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
64.99
13%
145
- C1 -
1SFC
2
VAMP2_RAT
A:
[25-93]
-----------------------------------------------------------------------------------------------
N
L
T
S
N
R
R
L
Q
Q
T
Q
A
Q
V
D
E
V
V
D
I
M
R
V
N
V
D
K
V
L
E
R
D
Q
K
L
S
E
L
D
D
R
A
D
A
L
Q
A
G
A
S
Q
F
E
T
S
A
A
K
L
K
R
K
Y
W
W
K
N
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
63.67
10%
87
- C1 -
2B9C
-
TPM1_RAT
A:
[98-233]
---------------------------------------------------------------------------------------------------------
E
L
D
R
A
Q
E
R
L
A
T
A
L
Q
K
L
E
E
A
E
K
A
A
D
E
S
E
R
G
M
K
V
I
E
S
R
A
Q
K
D
E
E
K
M
E
I
Q
E
I
Q
L
K
E
A
K
H
I
A
E
D
A
D
R
K
Y
E
E
V
A
R
K
L
V
I
I
E
S
D
L
E
R
A
E
E
R
A
E
L
S
E
G
K
C
A
E
L
E
E
E
L
K
T
V
T
N
N
L
K
S
L
E
D
K
V
E
E
L
L
S
K
N
Y
H
L
E
N
E
V
A
R
L
K
K
L
V
G
----------------------------------------------------------------------------------------------------------------------------------------------
39
Fugue
62.78
28%
210
* C1 *
2L5G
-
NCOR2_HUMAN
B:
[166-207]
---------------------------------------------------------------------------------------------------------------------
G
L
S
K
E
E
L
I
Q
N
M
D
R
V
D
R
E
I
T
M
V
E
Q
Q
I
S
K
L
K
K
K
Q
Q
Q
L
E
E
E
A
A
K
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
60.98
27%
-21
- C2 -
2QF2
1
PCKGC_RAT
A:
[350-408]
-----------------
I
K
T
I
Q
K
N
T
I
F
T
N
V
A
E
T
S
D
G
G
V
Y
W
E
G
I
D
E
P
L
A
P
G
V
T
I
T
S
W
K
N
K
E
W
R
P
Q
D
E
E
P
C
A
H
P
N
S
R
F
C
T
P
A
S
Q
C
P
I
I
D
P
A
W
E
S
P
E
G
V
P
I
E
G
I
I
F
G
G
R
R
P
A
G
V
P
L
V
Y
E
A
L
S
W
Q
H
G
V
F
V
G
A
A
M
R
S
E
A
T
A
A
A
E
H
K
G
K
V
I
M
H
D
P
F
A
M
R
P
F
F
G
Y
N
F
G
K
Y
L
A
H
W
L
S
M
A
H
R
P
A
A
K
L
P
K
I
F
H
V
N
W
F
R
K
D
K
N
G
K
F
L
W
P
G
F
G
E
N
S
R
V
L
E
W
M
F
G
R
I
E
G
E
D
S
A
K
L
T
P
I
G
Y
V
P
K
E
D
A
L
N
L
K
G
L
G
D
V
N
V
E
E
L
F
G
I
S
K
E
F
W
E
K
E
V
E
E
I
D
K
Y
L
E
D
Q
V
N
A
D
L
P
Y
E
I
E
R
E
L
R
A
L
K
Q
R
I
S
Q
M
-------------------------------------------------------------------------------------------
17
PsiBlast_PDB
60.53
27%
-13
* C2 *
2RKA
1
PCKGC_RAT
A:
[350-408]
-----------------
I
K
T
I
Q
K
N
T
I
F
T
N
V
A
E
T
S
D
G
G
V
Y
W
E
G
I
D
E
P
L
A
P
G
V
T
I
T
S
W
K
N
K
E
W
R
P
Q
D
E
E
P
C
A
H
P
N
S
R
F
C
T
P
A
S
Q
C
P
I
I
D
P
A
W
E
S
P
E
G
V
P
I
E
G
I
I
F
G
G
R
R
P
A
G
V
P
L
V
Y
E
A
L
S
W
Q
H
G
V
F
V
G
A
A
M
R
S
E
A
K
V
I
M
H
D
P
F
A
M
R
P
F
F
G
Y
N
F
G
K
Y
L
A
H
W
L
S
M
A
H
R
P
A
A
K
L
P
K
I
F
H
V
N
W
F
R
K
D
K
N
G
K
F
L
W
P
G
F
G
E
N
S
R
V
L
E
W
M
F
G
R
I
E
G
E
D
S
A
K
L
T
P
I
G
Y
V
P
K
E
D
A
L
N
L
K
G
L
G
D
V
N
V
E
E
L
F
G
I
S
K
E
F
W
E
K
E
V
E
E
I
D
K
Y
L
E
D
Q
V
N
A
D
L
P
Y
E
I
E
R
E
L
R
A
L
K
Q
R
I
S
Q
M
---------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
60.14
25%
-18
- C2 -
2FAH
2
PCKGM_CHICK
A:
[334-392]
-----------------
M
A
T
I
A
R
N
T
I
F
T
N
V
G
L
R
S
D
G
G
V
Y
W
D
G
L
D
E
P
T
E
P
G
V
T
Y
T
S
W
L
G
K
P
W
K
H
G
D
P
E
P
C
A
H
P
N
S
R
F
C
A
P
A
D
Q
C
P
I
M
D
P
R
W
D
D
P
E
G
V
P
I
D
A
I
I
F
G
G
R
R
P
R
G
V
P
L
V
V
E
A
F
G
W
R
H
G
V
F
M
G
S
A
M
R
S
E
A
T
A
A
A
E
H
K
G
G
R
L
M
H
D
P
F
A
M
R
P
F
F
G
Y
N
A
G
R
Y
L
E
H
W
L
S
T
G
L
R
S
N
A
R
L
P
R
L
F
H
V
N
W
F
L
R
D
N
E
G
R
F
V
W
P
G
F
G
H
N
A
R
V
L
A
W
I
F
G
R
I
Q
G
R
D
T
A
R
P
T
P
I
G
W
V
P
K
E
G
D
L
D
L
G
G
L
P
G
V
D
Y
S
Q
L
F
P
M
E
K
G
F
W
E
E
E
C
R
Q
L
R
E
Y
Y
G
E
N
F
G
A
D
L
P
R
D
V
M
A
E
L
E
G
L
E
E
R
V
R
K
M
-------------------------------------------------------------------------------------------
16
PsiBlast_PDB
59.90
27%
-14
- C2 -
2RK8
1
PCKGC_RAT
A:
[350-408]
-----------------
I
K
T
I
Q
K
N
T
I
F
T
N
V
A
E
T
S
D
G
G
V
Y
W
E
G
I
D
E
P
L
A
P
G
V
T
I
T
S
W
K
N
K
E
W
R
P
Q
D
E
E
P
C
A
H
P
N
S
R
F
C
T
P
A
S
Q
C
P
I
I
D
P
A
W
E
S
P
E
G
V
P
I
E
G
I
I
F
G
G
R
R
P
A
G
V
P
L
V
Y
E
A
L
S
W
Q
H
G
V
F
V
G
A
A
M
R
S
E
A
T
A
A
A
E
H
K
G
K
V
I
M
H
D
P
F
A
M
R
P
F
F
G
Y
N
F
G
K
Y
L
A
H
W
L
S
M
A
H
R
P
A
A
K
L
P
K
I
F
H
V
N
W
F
R
K
D
K
N
G
K
F
L
W
P
G
F
G
E
N
S
R
V
L
E
W
M
F
G
R
I
E
G
E
D
S
A
K
L
T
P
I
G
Y
V
P
K
E
D
A
L
N
L
K
G
L
G
D
V
N
V
E
E
L
F
G
I
S
K
E
F
W
E
K
E
V
E
E
I
D
K
Y
L
E
D
Q
V
N
A
D
L
P
Y
E
I
E
R
E
L
R
A
L
K
Q
R
I
S
Q
M
-------------------------------------------------------------------------------------------
15
PsiBlast_PDB
59.86
27%
-11
- C2 -
2RK7
1
PCKGC_RAT
A:
[350-408]
-----------------
I
K
T
I
Q
K
N
T
I
F
T
N
V
A
E
T
S
D
G
G
V
Y
W
E
G
I
D
E
P
L
A
P
G
V
T
I
T
S
W
K
N
K
E
W
R
P
Q
D
E
E
P
C
A
H
P
N
S
R
F
C
T
P
A
S
Q
C
P
I
I
D
P
A
W
E
S
P
E
G
V
P
I
E
G
I
I
F
G
G
R
R
P
A
G
V
P
L
V
Y
E
A
L
S
W
Q
H
G
V
F
V
G
A
A
M
R
S
E
A
V
I
M
H
D
P
F
A
M
R
P
F
F
G
Y
N
F
G
K
Y
L
A
H
W
L
S
M
A
H
R
P
A
A
K
L
P
K
I
F
H
V
N
W
F
R
K
D
K
N
G
K
F
L
W
P
G
F
G
E
N
S
R
V
L
E
W
M
F
G
R
I
E
G
E
D
S
A
K
L
T
P
I
G
Y
V
P
K
E
D
A
L
N
L
K
G
L
G
D
V
N
V
E
E
L
F
G
I
S
K
E
F
W
E
K
E
V
E
E
I
D
K
Y
L
E
D
Q
V
N
A
D
L
P
Y
E
I
E
R
E
L
R
A
L
K
Q
R
I
S
Q
M
----------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
59.77
27%
-14
- C2 -
3DT2
2
PCKGC_RAT
A:
[350-408]
-----------------
I
K
T
I
Q
K
N
T
I
F
T
N
V
A
E
T
S
D
G
G
V
Y
W
E
G
I
D
E
P
L
A
P
G
V
T
I
T
S
W
K
N
K
E
W
R
P
Q
D
E
E
P
C
A
H
P
N
S
R
F
C
T
P
A
S
Q
C
P
I
I
D
P
A
W
E
S
P
E
G
V
P
I
E
G
I
I
F
G
G
R
R
P
A
G
V
P
L
V
Y
E
A
L
S
W
Q
H
G
V
F
V
G
A
A
M
R
S
E
A
T
A
A
A
E
H
K
G
K
V
I
M
H
D
P
F
A
M
R
P
F
F
G
Y
N
F
G
K
Y
L
A
H
W
L
S
M
A
H
R
P
A
A
K
L
P
K
I
F
H
V
N
W
F
R
K
D
K
N
G
K
F
L
W
P
G
F
G
E
N
S
R
V
L
E
W
M
F
G
R
I
E
G
E
D
S
A
K
L
T
P
I
G
Y
V
P
K
E
D
A
L
N
L
K
G
L
G
D
V
N
V
E
E
L
F
G
I
S
K
E
F
W
E
K
E
V
E
E
I
D
K
Y
L
E
D
Q
V
N
A
D
L
P
Y
E
I
E
R
E
L
R
A
L
K
Q
R
I
S
Q
M
-------------------------------------------------------------------------------------------
4
PsiBlast_PDB
59.47
30%
90
- C1 -
1XGS
2
MAP2_PYRFU
A:
[77-141]
-----------------------------------------------------------------
D
Y
L
K
I
D
V
G
V
H
I
D
G
F
I
A
D
T
A
V
T
---
V
R
V
G
M
E
E
D
----
E
L
M
E
A
A
K
E
A
L
N
A
A
I
S
V
A
R
A
G
V
E
I
K
E
L
G
K
A
I
E
N
E
I
R
K
R
G
F
K
P
I
V
N
L
S
G
H
K
I
E
R
Y
K
L
H
A
G
I
S
I
P
N
I
Y
R
P
H
D
N
Y
V
L
K
E
G
D
V
F
A
I
E
P
F
A
T
I
G
A
G
Q
V
I
E
V
P
P
T
L
I
Y
M
Y
V
R
D
V
P
V
R
V
A
Q
A
R
F
L
L
A
K
I
K
R
E
Y
G
T
L
P
F
A
Y
R
W
L
Q
N
D
M
P
E
G
Q
L
K
L
A
L
K
T
L
E
K
A
G
A
I
Y
G
Y
P
V
L
K
E
I
R
N
G
I
V
A
Q
F
E
H
T
I
I
V
E
K
D
S
V
I
V
T
T
E
--------------------------------------------------------------------------------------------
5
PsiBlast_PDB
59.35
30%
87
- C1 -
1XGM
2
MAP2_PYRFU
A:
[77-141]
-----------------------------------------------------------------
D
Y
L
K
I
D
V
G
V
H
I
D
G
F
I
A
D
T
A
V
T
---
V
R
V
G
M
E
E
D
----
E
L
M
E
A
A
K
E
A
L
N
A
A
I
S
V
A
R
A
G
V
E
I
K
E
L
G
K
A
I
E
N
E
I
R
K
R
G
F
K
P
I
V
N
L
S
G
H
K
I
E
R
Y
K
L
H
A
G
I
S
I
P
N
I
Y
R
P
H
D
N
Y
V
L
K
E
G
D
V
F
A
I
E
P
F
A
T
I
G
A
G
Q
V
I
E
V
P
P
T
L
I
Y
M
Y
V
R
D
V
P
V
R
V
A
Q
A
R
F
L
L
A
K
I
K
R
E
Y
G
T
L
P
F
A
Y
R
W
L
Q
N
D
M
P
E
G
Q
L
K
L
A
L
K
T
L
E
K
A
G
A
I
Y
G
Y
P
V
L
K
E
I
R
N
G
I
V
A
Q
F
E
H
T
I
I
V
E
K
D
S
V
I
V
T
T
E
--------------------------------------------------------------------------------------------
10
PsiBlast_PDB
59.32
27%
-5
- C2 -
4OX2
2
?
A:
[348-406]
-----------------
I
K
T
I
Q
K
N
T
I
F
T
N
V
A
E
T
S
D
G
G
V
Y
W
E
G
I
D
E
P
L
A
P
G
V
T
I
T
S
W
K
N
K
E
W
R
P
---
E
P
C
A
H
P
N
S
R
F
C
T
P
A
S
Q
C
P
I
I
D
P
A
W
E
S
P
E
G
V
P
I
E
G
I
I
F
G
G
R
R
P
A
G
V
P
L
V
Y
E
A
L
S
W
Q
H
G
V
F
V
G
A
A
M
R
S
E
A
V
I
M
H
D
P
F
A
M
R
P
F
F
G
Y
N
F
G
K
Y
L
A
H
W
L
S
M
A
H
R
P
A
A
K
L
P
K
I
F
H
V
N
W
F
R
K
D
K
N
G
K
F
L
W
P
G
F
G
E
N
S
R
V
L
E
W
M
F
G
R
I
E
G
E
D
S
A
K
L
T
P
I
G
Y
V
P
K
E
D
A
L
N
L
K
G
L
G
D
V
N
V
E
E
L
F
G
I
S
K
E
F
W
E
K
E
V
E
E
I
D
K
Y
L
E
D
Q
V
N
A
D
L
P
Y
E
I
E
R
E
L
R
A
L
K
Q
R
I
S
Q
M
----------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
59.23
30%
88
- C1 -
1WKM
3
MAP2_PYRFU
A:
[77-141]
-----------------------------------------------------------------
D
Y
L
K
I
D
V
G
V
H
I
D
G
F
I
A
D
T
A
V
T
---
V
R
V
G
M
E
E
D
----
E
L
M
E
A
A
K
E
A
L
N
A
A
I
S
V
A
R
A
G
V
E
I
K
E
L
G
K
A
I
E
N
E
I
R
K
R
G
F
K
P
I
V
N
L
S
G
H
K
I
E
R
Y
K
L
H
A
G
I
S
I
P
N
I
Y
R
P
H
D
N
Y
V
L
K
E
G
D
V
F
A
I
E
P
F
A
T
I
G
A
G
Q
V
I
E
V
P
P
T
L
I
Y
M
Y
V
R
D
V
P
V
R
V
A
Q
A
R
F
L
L
A
K
I
K
R
E
Y
G
T
L
P
F
A
Y
R
W
L
Q
N
D
M
P
E
G
Q
L
K
L
A
L
K
T
L
E
K
A
G
A
I
Y
G
Y
P
V
L
K
E
I
R
N
G
I
V
A
Q
F
E
H
T
I
I
V
E
K
D
S
V
I
V
T
T
E
--------------------------------------------------------------------------------------------
9
PsiBlast_PDB
59.15
30%
80
- C1 -
2DFI
2
MAP2_PYRFU
A:
[77-141]
-----------------------------------------------------------------
D
Y
L
K
I
D
V
G
V
H
I
D
G
F
I
A
D
T
A
V
T
---
V
R
V
G
M
E
E
D
----
E
L
M
E
A
A
K
E
A
L
N
A
A
I
S
V
A
R
A
G
V
E
I
K
E
L
G
K
A
I
E
N
E
I
R
K
R
G
F
K
P
I
V
N
L
S
G
H
K
I
E
R
Y
K
L
H
A
G
I
S
I
P
N
I
Y
R
P
H
D
N
Y
V
L
K
E
G
D
V
F
A
I
E
P
F
A
T
I
G
A
G
Q
V
I
E
V
P
P
T
L
I
Y
M
Y
V
R
D
V
P
V
R
V
A
Q
A
R
F
L
L
A
K
I
K
R
E
Y
G
T
L
P
F
A
Y
R
W
L
Q
N
D
M
P
E
G
Q
L
K
L
A
L
K
T
L
E
K
A
G
A
I
Y
G
Y
P
V
L
K
E
I
R
N
G
I
V
A
Q
F
E
H
T
I
I
V
E
K
D
S
V
I
V
T
Q
D
M
I
N
K
S
T
--------------------------------------------------------------------------------------
8
PsiBlast_PDB
59.15
30%
89
- C1 -
1XGO
-
MAP2_PYRFU
A:
[77-141]
-----------------------------------------------------------------
D
Y
L
K
I
D
V
G
V
H
I
D
G
F
I
A
D
T
A
V
T
---
V
R
V
G
M
E
E
D
----
E
L
M
E
A
A
K
E
A
L
N
A
A
I
S
V
A
R
A
G
V
E
I
K
E
L
G
K
A
I
E
N
E
I
R
K
R
G
F
K
P
I
V
N
L
S
G
H
K
I
E
R
Y
K
L
H
A
G
I
S
I
P
N
I
Y
R
P
H
D
N
Y
V
L
K
E
G
D
V
F
A
I
E
P
F
A
T
I
G
A
G
Q
V
I
E
V
P
P
T
L
I
Y
M
Y
V
R
D
V
P
V
R
V
A
Q
A
R
F
L
L
A
K
I
K
R
E
Y
G
T
L
P
F
A
Y
R
W
L
Q
N
D
M
P
E
G
Q
L
K
L
A
L
K
T
L
E
K
A
G
A
I
Y
G
Y
P
V
L
K
E
I
R
N
G
I
V
A
Q
F
E
H
T
I
I
V
E
K
D
S
V
I
V
T
T
E
--------------------------------------------------------------------------------------------