@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_1128: (2015-12-21 )
MAKEKFNRTNPHVNIGTIGHVYHGKTTLSAAISAVLSLKGLAEMKDYDNIDNAPQEKERGITIATSHIEYETETRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLSRQVGVPHIVVFLNKQDMVDDQELLELVEMEVRELLSAYEFPGDDTPIVAGSALRALEEAKAGNVGEWGEKVLKLMAEVDSYIPTPERDTEKTFLMPVEDVFSIAGRGTVVTGRIERGVVKVGDEVEIVGIRATQKTTVTGVEMFRKELEKGEAGDNVGVLLRGTKKEEVERGMVLCKPGSITPHKKFEEEIYVLSKEEGGRHTPFFTNYRPQFYVRTTDVTGSITLPEGVEMVMPGDNVKITVELISPVALELGTKFAIREGGRTVGAGVVSNIIE
Atome Classification :
(45 SA)
.........10........20........30........40-..-------......50........60........70-.-----------------------.......80........90........100.......110........120.......130.......140.......150.......160.......170.......180-----..-----..-----....190.......200.......210.......220......----.230---........240.......250..-..----------..---------..260.......270.......280..---..---...290.......300.-...-...310.......--320...----....330.......340.......350.......360.......370.......380...----....390.......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MAKEKFNRTNP
H
V
N
I
G
T
I
G
H
V
YHG
K
T
T
L
S
A
A
I
S
A
V
L
S
L
K
G
L
-
A
E-------MKDYDNIDNAP
Q
E
KER
G
I
T
I
A
T
S
H
I
E
Y
E-T-----------------------ET
R
H
Y
A
HVDCPG
H
A
D
Y
V
K
N
M
I
TGAAQMD
G
A
I
L
V
V
SAADG-PMPQ
T
R
E
H
I
L
L
SRQVGV
P
H
I
V
V
F
LNKQDMV
D
D
Q
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
A
YEFPGDDTPI
V
A
G
S
A
L
R
A
L
E
E
------AK-----AG-----NV
G
E
W
G
E
K
V
L
K
L
M
A
E
V
D
S
YIPTPERDTE
K
T
F
L
M
P
V
E
D
V
F
S
IAG----R
G
T
----
V
V
TGRIERG
V
V
KVGD
E
V
E
I
V
-
G
I
-RA----------TQ---------KTT
V
T
G
V
E
M
F
R
K
E
L
EKGEAGDN
V
G
V
L
L
---RG---T
K
K
E
E
V
ER
G
M
V
L
CKPGS-ITP-
H
K
K
F
E
E
E
I
Y
V
L
SK--EEGGRH----T
P
F
FTNYR
P
Q
F
Y
V
R
T
TDVTGSITLPEG
V
E
M
VMPGD
N
V
K
I
T
V
E
LIS
P
V
A
L
ELG
T
K
F
A
I
REG----GRTV
G
A
G
V
V
S
N
IIE
17
PsiBlast_PDB
96.47
71%
-95
- C3 -
1EXM
2
EFTU1_THETH
A:
[3-405]
---
G
E
F
I
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
F
V
T
A
A
E
N
P
N
V
E
-------
V
K
D
Y
G
D
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
Y
E
-
T
-----------------------
A
K
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
L
E
Q
------
M
H
-----
R
N
PKTRR
G
E
N
E
W
V
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
V
D
K
P
F
L
M
P
V
E
D
V
F
T
I
T
G
----
R
G
T
----
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
-
G
L
-
A
P
E
---------
T
R
---------
K
T
V
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
V
L
L
---
R
G
---
V
S
R
E
E
V
E
R
G
Q
V
L
A
K
P
G
S
-
I
T
P
-
H
T
K
F
E
A
S
V
Y
V
L
K
K
--
E
E
G
G
R
H
----
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
V
V
Q
L
P
P
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
T
K
I
L
E
43
PsiBlast_CBE
96.38
73%
-110
- C3 -
4Q7J
2
EFTU1_ECOLI
B:
[8-392]
--------
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
T
V
L
A
K
T
Y
G
--------------------------------
S
H
V
E
Y
D
-
T
-----------------------
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
E
---------------------
G
D
A
E
W
E
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
----
R
G
T
----
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
-
G
I
-
K
E
----------
T
Q
---------
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
---
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
-
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
H
----
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
L
G
27
PsiBlast_CBE
96.33
73%
-97
- C3 -
3U6K
3
?
B:
[9-393]
--------
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
T
V
L
A
K
T
Y
G
-
G
A
-------
A
R
A
F
D
Q
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
Y
D
-
T
-----------------------
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
E
---------------------
G
D
A
E
W
E
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
----
R
G
T
----
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
-
G
I
-
K
E
----------
T
Q
---------
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
---
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
-
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
H
----
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
L
G
10
PsiBlast_PDB
96.22
73%
-98
- C3 -
1DG1
2
EFTU2_ECOLI
G:
[10-393]
---------
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
T
V
L
A
K
T
Y
G
-
G
A
-------
A
R
A
F
D
Q
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
Y
D
-
T
-----------------------
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
E
---------------------
G
D
A
E
W
E
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
----
R
G
T
----
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
-
G
I
-
K
E
----------
T
Q
---------
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
---
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
-
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
H
----
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
L
S
30
PsiBlast_CBE
96.18
73%
-107
- C3 -
4PC3
2
EFTU1_ECOLI
B:
[9-393]
--------
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
T
V
L
A
K
T
Y
G
-
G
---------------------
K
A
R
G
I
T
I
N
T
S
H
V
E
Y
D
-
T
-----------------------
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
E
---------------------
G
D
A
E
W
E
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
----
R
G
T
----
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
-
G
I
-
K
E
----------
T
Q
---------
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
---
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
-
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
H
----
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
L
G
11
PsiBlast_PDB
96.12
73%
-109
- C3 -
4PC6
2
?
A:
[9-393]
--------
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
T
V
L
A
K
T
Y
G
-
G
------------------------------
S
H
V
E
Y
D
-
T
-----------------------
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
E
---------------------
G
D
A
E
W
E
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
----
R
G
T
----
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
-
G
I
-
K
E
----------
T
Q
---------
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
---
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
-
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
H
----
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
L
G
7
PsiBlast_PDB
96.12
73%
-98
- C3 -
3U6K
3
EFTU1_ECOLI
A:
[9-393]
--------
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
T
V
L
A
K
T
Y
G
-
G
A
-------
A
R
A
F
D
Q
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
Y
D
-
T
-----------------------
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
E
---------------------
G
D
A
E
W
E
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
----
R
G
T
----
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
-
G
I
-
K
E
----------
T
Q
---------
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
---
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
-
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
H
----
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
L
G
14
PsiBlast_PDB
95.86
71%
-94
- C3 -
4H9G
12
EFTU1_THETH
A:
[2-405]
--
K
G
E
F
V
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
Y
V
A
A
A
E
N
P
N
V
E
-------
V
K
D
Y
G
D
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
Y
E
-
T
-----------------------
A
K
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
L
E
Q
------
M
H
-----
R
N
PKTRR
G
E
N
E
W
V
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
V
D
K
P
F
L
M
P
V
E
D
V
F
T
I
T
G
----
R
G
T
----
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
-
G
L
-
A
P
E
---------
T
R
---------
K
T
V
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
V
L
L
---
R
G
---
V
S
R
E
E
V
E
R
G
Q
V
L
A
K
P
G
S
-
I
T
P
-
H
T
K
F
E
A
S
V
Y
V
L
K
K
--
E
E
G
G
R
H
----
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
V
V
Q
L
P
P
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
T
K
I
L
E
29
PsiBlast_CBE
95.83
73%
-106
- C3 -
4PC6
2
?
B:
[9-393]
--------
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
T
V
L
A
K
T
Y
G
-
G
---------------------
K
A
R
G
I
----
S
H
V
E
Y
D
-
T
-----------------------
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
E
---------------------
G
D
A
E
W
E
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
----
R
G
T
----
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
-
G
I
-
K
E
----------
T
Q
---------
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
---
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
-
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
H
----
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
L
G
46
PsiBlast_CBE
95.78
73%
-98
- C3 -
1D8T
6
EFTU1_ECOLI
B:
[9-392]
---------
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
T
V
L
A
K
T
Y
G
-
G
A
-------
A
R
A
F
D
Q
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
Y
D
-
T
-----------------------
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
E
---------------------
G
D
A
E
W
E
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
----
R
G
T
----
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
-
G
I
-
K
E
----------
T
Q
---------
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
---
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
-
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
H
----
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
L
G
31
PsiBlast_CBE
95.76
73%
-105
- C3 -
4PC2
3
?
B:
[9-393]
--------
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
T
V
L
A
K
T
Y
G
-
G
A
-------
A
R
A
----------
K
A
R
G
I
T
I
N
T
S
H
V
E
Y
D
-
T
-----------------------
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
E
---------------------
G
D
A
E
W
E
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
----
R
G
T
----
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
-
G
I
-
K
E
----------
T
Q
---------
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
---
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
-
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
H
----
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
L
G
47
PsiBlast_CBE
95.74
73%
-95
- C3 -
1D8T
22
EFTU1_ECOLI
A:
[3-392]
---
E
K
F
E
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
T
V
L
A
K
T
Y
G
-
G
A
-------
A
R
A
F
D
Q
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
Y
D
-
T
-----------------------
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
E
---------------------
G
D
A
E
W
E
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
----
R
G
T
----
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
-
G
I
-
K
E
----------
T
Q
---------
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
---
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
-
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
H
----
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
L
G
40
PsiBlast_CBE
95.66
71%
-95
- C3 -
4LBW
11
EFTU1_THETH
A:
[2-404]
---
G
E
F
V
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
Y
V
A
A
A
E
N
P
N
V
E
-------
V
K
D
Y
G
D
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
Y
E
-
T
-----------------------
A
K
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
L
E
Q
------
M
H
-----
R
N
PKTRR
G
E
N
E
W
V
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
V
D
K
P
F
L
M
P
V
E
D
V
F
T
I
T
G
----
R
G
T
----
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
-
G
L
-
A
P
E
---------
T
R
---------
K
T
V
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
V
L
L
---
R
G
---
V
S
R
E
E
V
E
R
G
Q
V
L
A
K
P
G
S
-
I
T
P
-
H
T
K
F
E
A
S
V
Y
V
L
K
K
--
E
E
G
G
R
H
----
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
V
V
Q
L
P
P
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
T
K
I
L
E
20
PsiBlast_PDB
95.63
73%
-96
- C3 -
1EFC
2
EFTU1_ECOLI
A:
[8-392]
--------
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
T
V
L
A
K
T
Y
G
-
G
A
-------
A
R
A
F
D
Q
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
Y
D
-
T
-----------------------
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
E
---------------------
G
D
A
E
W
E
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
----
R
G
T
----
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
-
G
I
-
K
E
----------
T
Q
---------
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
---
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
-
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
H
----
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
L
S
32
PsiBlast_CBE
95.61
73%
-111
- C3 -
4PC1
1
?
B:
[9-393]
--------
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
T
V
L
A
K
T
Y
G
-
G
------------------------------
S
H
V
E
Y
D
-
T
-----------------------
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
E
---------------------
G
D
A
E
W
E
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
----
R
G
T
----
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
-
G
I
-
K
E
----------
T
Q
---------
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
---
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
-
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
H
----
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
L
G
105
HHSearch
95.59
74%
-111
- C3 -
3AVX
1
EFTU2_ECOLI (first)
A:
[290-677]
-----
F
E
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
T
V
L
A
K
T
Y
G
-
G
----------------------------
N
T
S
H
V
E
Y
D
-
T
-----------------------
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
E
G
------
D
---------------
A
E
W
E
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
----
R
G
T
----
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
-
G
I
-
K
E
----------
T
Q
---------
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
---
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
-
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
H
----
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
L
S
9
PsiBlast_PDB
95.58
73%
-94
- C3 -
4G5G
5
EFTU1_ECOLI
A:
[4-393]
---
E
K
F
E
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
T
V
L
A
K
T
Y
G
-
G
A
-------
A
R
A
F
D
Q
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
Y
D
-
T
-----------------------
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
E
---------------------
G
D
A
E
W
E
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
----
R
G
T
----
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
-
G
I
-
K
E
----------
T
Q
---------
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
---
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
-
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
H
----
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
L
G
28
PsiBlast_CBE
95.51
73%
-96
- C3 -
1DG1
2
EFTU2_ECOLI
H:
[10-393]
---------
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
T
V
L
A
K
T
Y
G
-
G
A
-------
A
R
A
F
D
Q
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
Y
D
-
T
-----------------------
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
E
---------------------
G
D
A
E
W
E
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
----
R
G
T
----
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
-
G
I
-
K
E
----------
T
Q
---------
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
---
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
-
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
H
----
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
L
S
38
PsiBlast_CBE
95.48
71%
-91
- C3 -
4LBZ
10
EFTU1_THETH
A:
[2-404]
---
G
E
F
V
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
Y
V
A
A
A
E
N
P
N
V
E
-------
V
K
D
Y
G
D
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
Y
E
-
T
-----------------------
A
K
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
L
E
Q
------
M
H
-----
R
N
PKTRR
G
E
N
E
W
V
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
V
D
K
P
F
L
M
P
V
E
D
V
F
T
I
T
G
----
R
G
T
----
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
-
G
L
-
A
P
E
---------
T
R
---------
K
T
V
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
V
L
L
---
R
G
---
V
S
R
E
E
V
E
R
G
Q
V
L
A
K
P
G
S
-
I
T
P
-
H
T
K
F
E
A
S
V
Y
V
L
K
K
--
E
E
G
G
R
H
----
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
V
V
Q
L
P
P
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
T
K
I
L
E
6
PsiBlast_PDB
95.37
71%
-95
- C3 -
1EFT
2
EFTU_THEAQ
A:
[1-405]
-
A
K
G
E
F
I
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
F
V
T
A
A
E
N
P
N
V
E
-------
V
K
D
Y
G
D
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
Y
E
-
T
-----------------------
A
K
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
L
E
E
M
H
K
NPK
T
K
-----
R
G
-----
E
-
N
E
W
V
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
V
D
K
P
F
L
M
P
V
E
D
V
F
T
I
T
G
----
R
G
T
----
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
-
G
L
-
A
P
E
---------
T
R
---------
K
T
V
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
L
L
L
---
R
G
---
V
S
R
E
E
V
E
R
G
Q
V
L
A
K
P
G
S
-
I
T
P
-
H
T
K
F
E
A
S
V
Y
V
L
K
K
--
E
E
G
G
R
H
----
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
V
V
R
L
P
Q
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
T
K
I
L
E
37
PsiBlast_CBE
95.34
71%
-93
- C3 -
4LC0
10
EFTU1_THETH
A:
[2-404]
---
G
E
F
V
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
Y
V
A
A
A
E
N
P
N
V
E
-------
V
K
D
Y
G
D
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
Y
E
-
T
-----------------------
A
K
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
L
E
Q
------
M
H
-----
R
N
PKTRR
G
E
N
E
W
V
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
V
D
K
P
F
L
M
P
V
E
D
V
F
T
I
T
G
----
R
G
T
----
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
-
G
L
-
A
P
E
---------
T
R
---------
K
T
V
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
V
L
L
---
R
G
---
V
S
R
E
E
V
E
R
G
Q
V
L
A
K
P
G
S
-
I
T
P
-
H
T
K
F
E
A
S
V
Y
V
L
K
K
--
E
E
G
G
R
H
----
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
V
V
Q
L
P
P
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
T
K
I
L
E
39
PsiBlast_CBE
95.17
71%
-94
- C3 -
4LBY
9
EFTU1_THETH
A:
[4-404]
-----
F
V
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
Y
V
A
A
A
E
N
P
N
V
E
-------
V
K
D
Y
G
D
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
Y
E
-
T
-----------------------
A
K
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
L
E
Q
------
M
H
-----
R
N
PKTRR
G
E
N
E
W
V
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
V
D
K
P
F
L
M
P
V
E
D
V
F
T
I
T
G
----
R
G
T
----
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
-
G
L
-
A
P
E
---------
T
R
---------
K
T
V
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
V
L
L
---
R
G
---
V
S
R
E
E
V
E
R
G
Q
V
L
A
K
P
G
S
-
I
T
P
-
H
T
K
F
E
A
S
V
Y
V
L
K
K
--
E
E
G
G
R
H
----
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
V
V
Q
L
P
P
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
T
K
I
L
E
102
HHSearch
95.09
73%
-96
- C3 -
2C78
3
EFTU1_THET8
A:
[9-405]
---------
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
Y
V
A
A
A
E
N
P
N
V
E
-------
V
K
D
Y
G
D
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
Y
E
-
T
-----------------------
A
K
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
L
E
Q
------
M
H
R
NPKT
R
R
-----
G
E
N
E
W
V
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
V
D
K
P
F
L
M
P
V
E
D
V
F
T
I
T
G
----
R
G
T
----
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
-
G
L
A
P
E
----------
T
R
---------
K
T
V
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
V
L
L
---
R
G
---
V
S
R
E
E
V
E
R
G
Q
V
L
A
K
P
G
S
-
I
T
P
-
H
T
K
F
E
A
S
V
Y
V
L
K
K
--
E
E
G
G
R
H
----
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
V
V
Q
L
P
P
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
T
K
I
L
E
8
PsiBlast_PDB
95.02
73%
-96
- C3 -
3U2Q
3
?
A:
[7-393]
------
E
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
T
V
L
A
K
T
Y
G
-
G
A
-------
A
R
A
F
D
Q
I
D
N
A
P
E
E
K
A
---
T
I
N
T
S
H
V
E
Y
D
-
T
-----------------------
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
E
---------------------
G
D
A
E
W
E
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
----
R
G
T
----
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
-
G
I
-
K
E
----------
T
Q
---------
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
---
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
-
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
H
----
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
L
G
41
PsiBlast_CBE
94.91
71%
-94
- C3 -
4LBV
12
EFTU1_THETH
A:
[2-404]
---
G
E
F
V
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
Y
V
A
A
A
E
N
P
N
V
E
-------
V
K
D
Y
G
D
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
Y
E
-
T
-----------------------
A
K
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
L
E
Q
------
M
H
-----
R
N
PKTRR
G
E
N
E
W
V
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
V
D
K
P
F
L
M
P
V
E
D
V
F
T
I
T
G
----
R
G
T
----
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
-
G
L
-
A
P
E
---------
T
R
---------
K
T
V
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
V
L
L
---
R
G
---
V
S
R
E
E
V
E
R
G
Q
V
L
A
K
P
G
S
-
I
T
P
-
H
T
K
F
E
A
S
V
Y
V
L
K
K
--
E
E
G
G
R
H
----
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
V
V
Q
L
P
P
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
T
K
I
L
E
36
PsiBlast_CBE
94.87
73%
-94
- C3 -
1EFC
2
EFTU1_ECOLI
B:
[8-392]
--------
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
T
V
L
A
K
T
Y
G
-
G
A
-------
A
R
A
F
D
Q
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
Y
D
-
T
-----------------------
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
E
---------------------
G
D
A
E
W
E
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
----
R
G
T
----
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
-
G
I
-
K
E
----------
T
Q
---------
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
---
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
-
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
H
----
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
L
S
13
PsiBlast_PDB
94.87
71%
-96
- C3 -
2C78
3
EFTU1_THET8
A:
[9-405]
---------
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
Y
V
A
A
A
E
N
P
N
V
E
-------
V
K
D
Y
G
D
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
Y
E
-
T
-----------------------
A
K
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
L
E
Q
------
M
H
-----
R
N
PKTRR
G
E
N
E
W
V
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
V
D
K
P
F
L
M
P
V
E
D
V
F
T
I
T
G
----
R
G
T
----
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
-
G
L
-
A
P
E
---------
T
R
---------
K
T
V
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
V
L
L
---
R
G
---
V
S
R
E
E
V
E
R
G
Q
V
L
A
K
P
G
S
-
I
T
P
-
H
T
K
F
E
A
S
V
Y
V
L
K
K
--
E
E
G
G
R
H
----
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
V
V
Q
L
P
P
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
T
K
I
L
E
35
PsiBlast_CBE
94.56
73%
-98
- C3 -
2BVN
3
EFTU2_ECOLI
A:
[9-392]
---------
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
T
V
L
A
K
T
Y
G
-
G
--------------------
E
K
A
R
G
I
T
I
N
T
S
H
V
E
Y
D
-
T
-----------------------
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
E
---------------------
G
D
A
E
W
E
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
----
R
G
T
----
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
-
G
I
-
K
E
----------
T
Q
---------
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
---
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
-
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
H
----
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
L
S
44
PsiBlast_CBE
94.51
73%
-94
- C3 -
2FX3
2
EFTU1_ECOLI
A:
[7-392]
-------
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
T
V
L
A
K
T
Y
G
-
G
A
-------
A
R
A
F
D
Q
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
Y
D
-
T
-----------------------
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
E
---------------------
G
D
A
E
W
E
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
----
R
G
T
----
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
-
G
I
-
K
E
----------
T
Q
---------
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
---
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
-
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
H
----
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
L
G
3
PsiBlast_PDB
94.46
71%
-92
- C3 -
1B23
5
EFTU_THEAQ
P:
[1-405]
-
A
K
G
E
F
I
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
Y
V
A
A
A
E
N
P
N
V
E
-------
V
K
D
Y
G
D
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
Y
E
-
T
-----------------------
A
K
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
L
E
E
MHKNPK
T
K
-----
R
G
-----
E
-
N
E
W
V
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
V
D
K
P
F
L
M
P
V
E
D
V
F
T
I
T
G
----
R
G
T
----
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
-
G
L
-
A
P
E---------
T
R
---------
K
T
V
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
L
L
L
---
R
G
---
V
S
R
E
E
V
E
R
G
Q
V
L
A
K
P
G
S
-
I
T
P
-
H
T
K
F
E
A
S
V
Y
I
L
K
K
--
E
E
G
G
R
H
----
T
G
F
F
T
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
V
V
R
L
P
Q
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
T
K
I
L
E
16
PsiBlast_PDB
94.22
71%
-96
- C3 -
2C77
4
EFTU2_THET8
A:
[2-405]
--
K
G
E
F
I
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
Y
V
T
A
A
E
N
P
N
V
E
-------
V
K
D
Y
G
D
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
Y
E
-
T
-----------------------
A
K
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
L
E
Q
------
M
H
-----
R
N
PKTRR
G
E
N
E
W
V
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
V
D
K
P
F
L
M
P
V
E
D
V
F
T
I
T
G
----
R
G
T
----
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
-
G
L
-
A
P
E
---------
T
R
---------
K
T
V
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
V
L
L
---
R
G
---
V
S
R
E
E
V
E
R
G
Q
V
L
A
K
P
G
S
-
I
T
P
-
H
T
K
F
E
A
S
V
Y
V
L
K
K
--
E
E
G
G
R
H
----
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
V
V
Q
L
P
P
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
T
K
I
L
E
21
PsiBlast_CBE
94.15
71%
-97
- C3 -
1TUI
2
EFTU_THEAQ
C:
[9-405]
---------
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
Y
V
A
A
A
E
N
P
N
V
E
-------
V
K
D
Y
G
D
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
Y
E
-
T
-----------------------
A
K
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
L
E
E
MHKNPK
T
K
-----
R
G
-----
E
-
N
E
W
V
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
V
D
K
P
F
L
M
P
V
E
D
V
F
T
I
T
G
----
R
G
T
----
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
-
G
L
-
A
P
E---------
T
R
---------
K
T
V
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
L
L
L
---
R
G
---
V
S
R
E
E
V
E
R
G
Q
V
L
A
K
P
G
S
-
I
T
P
-
H
T
K
F
E
A
S
V
Y
I
L
K
K
--
E
E
G
G
R
H
----
T
G
F
F
T
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
V
V
R
L
P
Q
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
T
K
I
L
E
15
PsiBlast_PDB
94.13
73%
-94
- C3 -
1OB2
4
EFTU2_ECOLI
A:
[1-392]
-
A
K
E
K
F
E
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
T
V
L
A
K
T
Y
G
-
G
A
-------
A
R
A
F
D
Q
I
D
N
A
P
E
E
K
A
R
G
I
T
I
N
T
S
H
V
E
Y
D
-
T
-----------------------
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
E
---------------------
G
D
A
E
W
E
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
----
R
G
T
----
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
-
G
I
-
K
E
----------
T
Q
---------
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
---
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
-
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
H
----
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
L
S
34
PsiBlast_CBE
94.09
73%
-98
- C3 -
2BVN
3
EFTU2_ECOLI
B:
[6-392]
------
E
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
T
V
L
A
K
T
Y
G
------------------------
A
R
G
I
T
I
N
T
S
H
V
E
Y
D
-
T
-----------------------
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
E
---------------------
G
D
A
E
W
E
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
----
R
G
T
----
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
-
G
I
-
K
E
----------
T
Q
---------
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
---
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
-
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
H
----
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
L
S
33
PsiBlast_CBE
93.74
71%
-105
- C3 -
1HA3
5
EFTU1_THET8
B:
[3-405]
---
G
E
F
I
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
F
V
T
A
A
E
N
P
N-------------------------------
A
H
V
E
Y
E
-
T
-----------------------
A
K
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
L
E
Q
------
M
H
-----
R
N
PKTRR
G
E
N
E
W
V
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
V
D
K
P
F
L
M
P
V
E
D
V
F
T
I
T
G
----
R
G
T
----
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
-
G
L
-
A
P
E
---------
T
R
---------
K
T
V
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
V
L
L
---
R
G
---
V
S
R
E
E
V
E
R
G
Q
V
L
A
K
P
G
S
-
I
T
P
-
H
T
K
F
E
A
S
V
Y
V
L
K
K
--
E
E
G
G
R
H
----
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
V
V
Q
L
P
P
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
T
K
I
L
E
22
PsiBlast_CBE
93.49
71%
-94
- C3 -
1TUI
2
EFTU_THEAQ
B:
[9-405]
---------
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
Y
V
A
A
A
E
N
P
N
V
E
-------
V
K
D
Y
G
D
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
Y
E
-
T
-----------------------
A
K
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
L
E
E
MHKNPK
T
K
-----
R
G
-----
E
-
N
E
W
V
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
V
D
K
P
F
L
M
P
V
E
D
V
F
T
I
T
G
----
R
G
T
----
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
-
G
L
-
A
P
E---------
T
R
---------
K
T
V
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
L
L
L
---
R
G
---
V
S
R
E
E
V
E
R
G
Q
V
L
A
K
P
G
S
-
I
T
P
-
H
T
K
F
E
A
S
V
Y
I
L
K
K
--
E
E
G
G
R
H
----
T
G
F
F
T
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
V
V
R
L
P
Q
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
T
K
I
L
E
2
PsiBlast_PDB
93.42
71%
-96
- C3 -
1TUI
2
EFTU_THEAQ
A:
[9-405]
---------
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
Y
V
A
A
A
E
N
P
N
V
E
-------
V
K
D
Y
G
D
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
Y
E
-
T
-----------------------
A
K
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
L
E
E
M
H
K
NPK
T
K
-----
R
G
-----
E
-
N
E
W
V
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
V
D
K
P
F
L
M
P
V
E
D
V
F
T
I
T
G
----
R
G
T
----
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
-
G
L
-
A
P
E
---------
T
R
---------
K
T
V
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
L
L
L
---
R
G
---
V
S
R
E
E
V
E
R
G
Q
V
L
A
K
P
G
S
-
I
T
P
-
H
T
K
F
E
A
S
V
Y
I
L
K
K
--
E
E
G
G
R
H
----
T
G
F
F
T
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
V
V
R
L
P
Q
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
T
K
I
L
E
18
PsiBlast_PDB
93.36
71%
-98
- C3 -
1HA3
5
EFTU1_THET8
A:
[3-405]
---
G
E
F
I
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
F
V
T
A
A
E
N
P
N
V
E
-------
V
K
D
Y
G
D
I
D
K
------------
T
A
H
V
E
Y
E
-
T
-----------------------
A
K
R
H
Y
S
H
V
D
C
P
G
H
A
D
Y
I
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
S
A
A
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
A
R
Q
V
G
V
P
Y
I
V
V
F
M
N
K
V
D
M
V
D
D
P
E
L
L
D
L
V
E
M
E
V
R
D
L
L
N
Q
Y
E
F
P
G
D
E
V
P
V
I
R
G
S
A
L
L
A
L
E
Q
------
M
H
-----
R
N
PKTRR
G
E
N
E
W
V
D
K
I
W
E
L
L
D
A
I
D
E
Y
I
P
T
P
V
R
D
V
D
K
P
F
L
M
P
V
E
D
V
F
T
I
T
G
----
R
G
T
----
V
A
T
G
R
I
E
R
G
K
V
K
V
G
D
E
V
E
I
V
-
G
L
-
A
P
E
---------
T
R
---------
K
T
V
V
T
G
V
E
M
H
R
K
T
L
Q
E
G
I
A
G
D
N
V
G
V
L
L
---
R
G
---
V
S
R
E
E
V
E
R
G
Q
V
L
A
K
P
G
S
-
I
T
P
-
H
T
K
F
E
A
S
V
Y
V
L
K
K
--
E
E
G
G
R
H
----
T
G
F
F
S
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
V
V
Q
L
P
P
G
V
E
M
V
M
P
G
D
N
V
T
F
T
V
E
L
I
K
P
V
A
L
E
E
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
T
K
I
L
E
52
PsiBlast_CBE
93.21
71%
-93
- C3 -
4IW3
3
EFTU1_PSEPK
B:
[46-433]
---------
L
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
R
V
C
S
E
V
F
G
-
S
-------------
K
I
D
S
A
P
E
E
K
A
R
G
I
T
I
N
T
A
H
V
E
Y
N
-
S
-----------------------
T
I
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
C
S
A
A
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
S
R
Q
V
G
V
P
Y
I
V
V
F
L
N
K
A
D
L
V
--
A
E
L
L
E
L
V
E
M
E
V
R
D
L
L
S
T
Y
D
F
P
G
D
D
T
P
I
I
I
G
S
A
R
M
A
L
E
G
------
K
D
-----
D
N
-----
E
M
G
T
T
A
V
K
--
K
L
V
E
T
L
D
S
Y
I
P
E
P
V
R
A
I
D
Q
P
F
L
M
P
I
E
D
V
F
S
I
S
G
----
R
G
T
----
V
V
T
G
R
I
E
R
G
I
V
R
V
Q
D
P
L
E
I
V
-
G
L
-
R
D
----------
T
T
---------
T
T
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
C
G
V
L
L
---
R
G
---
T
K
R
D
D
V
E
R
G
Q
V
L
V
K
P
G
S
-
V
K
P
-
H
T
K
F
T
A
E
V
Y
V
L
S
K
--
E
E
G
G
R
H
----
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
N
C
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
Q
M
T
V
T
L
I
K
T
I
A
M
E
D
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
I
I
E
51
PsiBlast_CBE
93.04
71%
-97
- C3 -
4IW3
4
EFTU1_PSEPK
K:
[46-433]
---------
L
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
L
T
R
V
C
S
E
V
F
G
---------------
K
I
D
S
A
P
E
E
K
A
-
G
I
T
I
N
T
A
H
V
E
Y
N
-
S
-----------------------
T
I
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
C
S
A
A
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
S
R
Q
V
G
V
P
Y
I
V
V
F
L
N
K
A
D
L
V
--
A
E
L
L
E
L
V
E
M
E
V
R
D
L
L
S
T
Y
D
F
P
G
D
D
T
P
I
I
I
G
S
A
R
M
A
L
E
G
------
K
D
-----
D
N
-----
E
M
G
T
T
A
V
K
--
K
L
V
E
T
L
D
S
Y
I
P
E
P
V
R
A
I
D
Q
P
F
L
M
P
I
E
D
V
F
S
I
S
G
----
R
G
T
----
V
V
T
G
R
I
E
R
G
I
V
R
V
Q
D
P
L
E
I
V
-
G
L
-
R
D
----------
T
T
---------
T
T
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
C
G
V
L
L
---
R
G
---
T
K
R
D
D
V
E
R
G
Q
V
L
V
K
P
G
S
-
V
K
P
-
H
T
K
F
T
A
E
V
Y
V
L
S
K
--
E
E
G
G
R
H
----
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
N
C
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
Q
M
T
V
T
L
I
K
T
I
A
M
E
D
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
I
I
E
12
PsiBlast_PDB
91.51
73%
-103
- C3 -
4PC7
3
EFTU1_ECOLI
A:
[9-393]
--------
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
T
V
L
A
K
T
Y
G
-
G
--------------------------
T
I
N
T
S
H
V
E
Y
D
-
T
-----------------------
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
E
---------------------
G
D
A
E
W
E
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
E
P
E
R
A
I
D
K
P
F
L
L
P
I
E
D
V
F
S
I
S
G
----
R
G
T
----
V
V
T
G
R
V
E
R
G
I
I
K
V
G
E
E
V
E
I
V
-
G
I
-
K
E
----------
T
Q
---------
K
S
T
C
T
G
V
E
M
F
R
K
L
L
D
E
G
R
A
G
E
N
V
G
V
L
L
---
R
G
---
I
K
R
E
E
I
E
R
G
Q
V
L
A
K
P
G
T
-
I
K
P
-
H
T
K
F
E
S
E
V
Y
I
L
S
K
--
D
E
G
G
R
H
----
T
P
F
F
K
G
Y
R
P
Q
F
Y
F
R
T
T
D
V
T
G
T
I
E
L
P
E
G
V
E
M
V
M
P
G
D
N
I
K
M
V
V
T
L
I
H
P
I
A
M
D
D
G
L
R
F
A
I
R
E
G
----
G
R
T
V
G
A
G
V
V
A
K
V
L
G
130
Fugue
72.93
31%
-76
- C3 -
1KK1
3
IF2G_PYRAB
A:
[6-410]
-------
S
R
Q
A
E
V
N
I
G
M
V
G
H
V
D
H
G
K
T
T
L
T
K
A
L
T
G
V
W
T
D
S
E
E
-
L
R
RGITIK
I
G
F
A
D
A
E
I
R
R
C
P
N
C
G
R
Y
S
T
S
P
V
C
P
Y
C
G
H
E
T
E
-----------------------
F
V
R
R
V
S
F
I
D
A
P
G
H
E
A
L
M
T
T
M
L
A
G
A
S
L
M
D
G
A
I
L
V
I
A
A
N
E
P
C
P
R
P
Q
T
R
E
H
L
M
A
L
Q
I
I
G
Q
K
N
I
I
I
A
Q
N
K
I
E
L
V
D
K
E
K
A
L
E
N
Y
R
-
Q
I
K
E
F
I
E
--
G
T
V
A
E
N
A
P
I
I
P
I
S
A
L
H
-----------------------------
G
A
N
I
D
V
L
V
K
A
I
E
D
F
I
P
T
P
K
R
D
P
N
K
P
P
K
M
L
V
L
R
S
F
D
V
N
K
----
P
G
K
LV
G
G
V
L
D
G
S
I
V
Q
G
K
L
K
V
G
D
E
I
E
I
R
P
G
V
-
P
Y
----------
E
E
HG
R
I
K
Y
E
P
I
T
T
E
I
V
S
L
Q
A
G
G
Q
F
V
E
E
A
Y
P
G
G
L
V
G
V
G
T
KLD
P
Y
---
L
T
K
G
D
L
M
A
G
N
V
V
G
K
P
G
K
-
L
P
P
V
W
D
S
L
R
L
E
V
H
L
L
E
R
VV
E
Q
E
L
K
V
----
E
P
I
K
R
K
E
V
L
L
L
N
V
G
T
A
R
T
M
G
L
V
T
G
L
G
K
D
---------
E
I
E
V
K
L
Q
I
P
V
C
A
E
P
G
D
R
V
A
I
S
R
Q
I
GS
R
W
R
L
I
G
Y
G
I
I
K
E
---
114
HHSearch
72.35
32%
-69
- C3 -
1KK1
3
IF2G_PYRAB
A:
[6-410]
-------
S
R
Q
A
E
V
N
I
G
M
V
G
H
V
D
H
G
K
T
T
L
T
K
A
L
T
G
V
---------------------
W
T
D
--
S
E
E
L
R
R
G
I
T
I
K
I
G
F
A
D
A
E
-
I
R
R
C
PNCGRYSTSPVCPYCG
H
E
T
E
F
V
R
R
V
S
F
I
D
A
P
G
H
E
A
L
M
T
T
M
L
A
G
A
S
L
M
D
G
A
I
L
V
I
A
A
N
E
P
C
P
R
P
Q
T
R
E
H
L
M
A
L
Q
I
I
G
Q
K
N
I
I
I
A
Q
N
K
I
E
L
V
D
K
E
K
-
A
L
E
N
Y
R
Q
I
K
E
F
I
E
G
T
V
--
A
E
N
A
P
I
I
P
I
S
A
L
H
G
-----------------------------
A
N
I
D
V
L
V
K
A
I
E
D
F
I
P
T
P
K
R
D
P
N
K
P
P
K
M
L
V
L
R
S
F
D
V
N
K
PGKL
V
G
G
----
V
L
D
G
S
I
V
Q
G
K
L
K
V
G
D
E
I
E
I
R
-
P
G
-
V
P
Y
E
E
HG
R
I
K
Y
E
P
I
---------
T
T
E
I
V
S
L
Q
A
G
G
Q
F
V
E
E
A
Y
P
G
G
L
V
G
V
G
T
---
K
L
DPY
L
T
K
G
D
L
M
A
G
N
V
V
G
K
P
G
K
L
P
P
V
-
W
D
S
L
R
L
E
V
H
L
L
E
R
--
V
V
--
E
Q
ELKV
E
P
I
K
R
K
E
V
L
L
L
N
V
G
T
A
R
T
M
G
L
V
T
G
L
---------
G
K
D
E
I
E
V
K
L
Q
I
P
V
C
A
E
P
G
D
R
V
A
I
S
R
Q
I
GS
R
W
R
L
I
G
Y
G
I
I
K
E
---
45
PsiBlast_CBE
65.84
73%
-117
- C3 -
1ETU
2
EFTU1_ECOLI
A:
[5-200]
-----
F
E
R
T
K
P
H
V
N
V
G
T
I
G
H
V
D
H
G
K
T
T
L
T
A
A
I
T
T
V
L
A
K
T
Y
G
---------------------------
I
T
I
N
T
S
H
V
E
Y
D
-
T
-----------------------
P
T
R
H
Y
A
H
V
D
C
P
G
H
A
D
Y
V
K
N
M
I
T
G
A
A
Q
M
D
G
A
I
L
V
V
A
A
T
D
G
-
P
M
P
Q
T
R
E
H
I
L
L
G
R
Q
V
G
V
P
Y
I
I
V
F
L
N
K
C
D
M
V
D
D
E
E
L
L
E
L
V
E
M
E
V
R
E
L
L
S
Q
Y
D
F
P
G
D
D
T
P
I
V
R
G
S
A
L
K
A
L
E
---------------------
G
D
A
E
W
E
A
K
I
L
E
L
A
G
F
L
D
S
Y
I
P
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
135
Fugue
5.79
48%
168
- C3 -
2P8W
1
S:
[1-35]
----------------------------------
T
A
A
E
N
P
N
-
V
E
-------
V
K
D
Y
G
D
I
D
K
A
P
E
E
R
A
R
G
I
T
I
N
T
A
H
V
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------