@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_1163: (2015-12-21 )
MFHEFRDEISVLKANNPHFDKIFEKHNQLDDDIKTAEQQNASDAEISHMKKQKLKLKDEIHSMIIEYREKQKSERA
Atome Classification :
(20 SA)
--------------------------------------------------------------------------------------------------------------------------......--.-..10........20.....--------...30------...--------.....-----40.......----.50...-.....60........70.....-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------------------------------------------------------------------------------------------------------------------M
F
H
E
F
R
--
D
-
E
I
S
VLKANNP
H
F
D
K
I
F
E
K
H--------NQLD
D
------
D
I
K
--------
T
A
E
QQ-----NAS
D
A
E
I
S
H
----
M
K
K
Q
K
L
-
K
L
K
D
E
I
H
S
M
I
I
E
Y
R
E
K
Q
KSERA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
88.36
99%
-22
- C3 -
1ZHC
-
?
A:
[1-76]
--------------------------------------------------------------------------------------------------------------------------
M
F
H
E
F
R
--
D
-
E
I
S
V
L
K
A
N
N
P
H
F
D
K
I
F
E
K
H
--------
N
Q
L
D
D
------
D
I
K
--------
T
A
E
Q
Q
-----
N
A
S
D
A
E
V
S
H
----
M
K
K
Q
K
L
-
K
L
K
D
E
I
H
S
M
I
I
E
Y
R
E
K
Q
K
S
E
R
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
Fugue
88.16
98%
-22
- C3 -
1ZHC
-
?
A:
[1-76]
--------------------------------------------------------------------------------------------------------------------------
M
F
H
E
F
R
--
D
-
E
I
S
V
L
K
A
N
N
P
H
F
D
K
I
F
E
K
H
--------
N
Q
L
D
D
------
D
I
K
--------
T
A
E
Q
Q
-----
N
A
S
D
A
E
V
S
H
----
M
K
K
Q
K
L
-
K
L
K
D
E
I
H
S
M
I
I
E
Y
R
E
K
Q
K
S
E
R
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
88.16
98%
-22
- C3 -
1ZHC
-
?
A:
[1-76]
--------------------------------------------------------------------------------------------------------------------------
M
F
H
E
F
R
--
D
-
E
I
S
V
L
K
A
N
N
P
H
F
D
K
I
F
E
K
H
--------
N
Q
L
D
D
------
D
I
K
--------
T
A
E
Q
Q
-----
N
A
S
D
A
E
V
S
H
----
M
K
K
Q
K
L
-
K
L
K
D
E
I
H
S
M
I
I
E
Y
R
E
K
Q
K
S
E
R
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
Fugue
55.81
6%
-2
- C3 -
3PLT
-
LSP1_YEAST
A:
[51-264]
----------------------------------------------------GPELA
R
K
L
S
Q
L
V
K
T
E
K
G
V
L
R
A
M
E
V
V
A
S
E
R
R
E
A
A
K
Q
L
S
L
W
G
ADND
D
D
V
S
D
V
T
D
K
L
G
V
L
I
Y
E
L
G
E
L
Q
D
Q
F
I
D
K
Y
D
Q
Y
R
--
V
-
T
L
K
S
I
R
N
I
E
A
S
V
Q
P
S
R
D
R
K
--------
E
K
I
T
D
------
E
I
A
--------
H
L
K
Y
K
-----
D
P
Q
S
T
K
I
P
V
----
L
E
Q
E
L
V
-
R
A
E
A
E
S
L
V
A
E
A
Q
L
S
N
I
T
R
E
K
L
K
A
A
Y
S
Y
M
F
D
S
L
R
E
L
S
E
K
F
A
L
I
A
G
Y
G
K
A
L
L
E
L
LDD
S
P
V
T
PG
E
A
R
P
AYDG
Y
E
A
S
R
Q
I
I
M
D
A
E
S
A
L
E
S
WTLD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
Fugue
51.05
25%
2
- C3 -
1R5I
3
?
D:
[3-216]
------------SMKLRVENP
K
K
A
Q
K
HFVQNLNNVVFT
N
K
E
L
E
D
I
Y
N
L
S
NKEET
K
E
V
L
K
L
F
K
L
K
V
N
Q
F
Y
R
H
A
F
G
I
V
N
D
YNGLLE
Y
K
E
I
F
N
M
M
F
L
K
L
S
V
V
F
D
T
Q
R
K
E
A
NN
V
E
Q
I
K
R
N
I
A
I
L
D
E
I
M
A
K
A
D
--
N
-
D
L
S
Y
F
I
S
Q
N
K
N
F
Q
E
L
W
D
K
A
--------
V
K
L
T
K
------
E
M
K
--------
I
K
---------------------
L
K
G
Q
K
L
-
D
L
R
D
G
-
E
V
A
I
N
K
V
R
E
L
F
G
S
D
K
N
V
K
E
L
W
W
F
R
S
L
L
V
K
G
V
Y
L
I
K
R
Y
Y
E
GDIELKTTS
D
F
A
K
A
V
F
ED------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
50.52
11%
-11
- C3 -
1HX1
-
B:
[4-70]
----------------------------------------------------------------------------------------------------------------------------
P
Q
E
E
--
V
-
E
L
K
K
L
K
H
L
E
K
S
V
E
K
I
A
D
Q
L
--------
E
E
L
N
K
------
E
L
T
--------
G
I
Q
Q
G
FLP
K
-
D
L
Q
A
E
A
L
C
K
----
L
D
R
R
V
K
-
A
T
I
E
Q
F
M
K
I
L
E
E
I
D
T
L
I
L
P
E
N
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
HHSearch
48.74
21%
-7
- C3 -
3TNU
-
K2C5_HUMAN
B:
[398-455]
---------------------------------------------------------------------------------------------------------------------------------------------
A
E
I
D
N
V
K
K
Q
C
--------
A
N
L
Q
N
------
A
I
A
--------
D
A
E
Q
R
G
E
L
A
L
K
D
A
R
N
K
L
A
E
----
L
E
E
A
L
Q
-
K
A
K
Q
D
M
A
R
L
L
R
E
Y
Q
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
48.51
21%
6
- C3 -
2JEE
-
ZAPB_ECOLI
A:
[30-78]
------------------------------------------------------------------------------------------------------------------------------------------------
E
E
L
K
E
K
N
--------
N
S
L
S
Q
------
E
V
Q
--------
N
A
Q
H
Q
R
----
E
E
L
E
R
E
N
N
H
----
L
K
E
Q
Q
N
-
G
W
Q
E
R
L
Q
A
L
L
G
R
M
E
E
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
HHSearch
45.90
16%
-50
- C3 -
3PXP
3
?
A:
[192-216]
----------------------------------------------------------------------------------------------------------------------------
G
Y
F
V
--
E
-
L
L
D
N
L
M
Q
-
Y
R
E
F
K
R
F
W
E
R
A
--------
H
L
E
T
E
------
D
T
S
--------
A
E
N
F
W
-----
Y
Q
Y
T
H
P
V
Y
G
----
L
L
S
Y
V
S
-
S
R
S
Q
I
P
T
S
M
G
L
L
S
M
H
T
Y
I
P
L
S
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
45.36
17%
-3
- C3 -
2A3D
-
?
A:
[29-69]
---------------------------------------------------------------------------------------------------------------------------------------------------------------
A
A
F
E
K
------
E
I
A
--------
A
F
E
S
E
LQAYK
G
K
G
N
P
E
V
E
A
----
L
R
K
E
A
A
-
A
I
R
D
E
L
Q
A
Y
R
H
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
HHSearch
42.87
13%
6
- C3 -
3TNU
-
K1C14_HUMAN
A:
[344-400]
----------------------------------------------------------------------------------------------------------------------------------------------
E
L
Q
S
Q
L
S
M
K
--------
A
S
L
E
N
------
S
L
E
--------
E
T
K
G
R
Y
C
M
Q
L
A
Q
I
Q
E
M
I
G
S
----
V
E
E
Q
L
A
-
Q
L
R
C
E
M
E
Q
Q
N
Q
E
Y
K
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
Fugue
41.78
20%
-5
- C3 -
2Q97
1
?
T:
[1-109]
-------------------------------------------------------------------------------------------------MQQELGLLRPEERLIAGQAKAAALQ
T
V
H
Q
L
G
--
A
V
A
L
T
P
E
Q
A
K
A
A
L
L
D
E
I
L
R
A
T
--------
Q
N
L
D
--------
L
R
--------
K
Y
E
N
L
-----
N
T
E
Q
Q
K
A
Y
E
----
Q
V
Q
R
D
L
S
Q
L
S
P
E
T
K
A
L
L
I
E
N
Q
R
K
E
K
T
L
L
E
KARKLFQR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
Fugue
41.66
22%
1
- C3 -
4GA6
3
AMPPA_THEKO
A:
[1-493]
--------------------------------------------------------M
K
A
K
I
R
I
L
DMFSGRY
T
V
L
I
N
E
E
D
A
K
E
A
KLHPDD
L
V
K
I
E
A
G
K
K
A
V
Y
G
S
V
A
L
S
NLVGKG
E
V
G
I
S
RDVL
D
L
H
N
F
S
EG
E
-
T
V
S
V
I
P
A
G
T
P
E
S
V
R
Y
I
K
K
K
M
H
G
E
K
L
R
K
V
E
I
E
A
------
I
V
R
--------
D
I
V
D
R
-----
K
L
R
D
I
E
I
S
S
F
V
T
A
L
E
I
N
G
L
-
D
-
M
D
E
I
A
A
L
T
I
A
M
A
E
T
G
D
M
L
D
I
DRKP
I
M
D
V
H
S
IGGVPGNK
T
N
I
L
V
V
P
I
V
A
A
A
GLTIP
K
T
S
S
R
A
ITSAAG
T
A
D
V
V
E
V
F
ADVSFS
L
D
E
I
K
R
I
V
E
K
VGACLVWGGALNLA
P
A
D
D
I
T
I
K
A
E
R
A
L
SIDP
T
G
L
M
L
A
S
I
M
S
K
K
Y
A
M
GSQ
Y
V
L
I
D
I
P
T
G
KGVKVET
V
E
E
A
R
S
L
A
R
D
F
I
E
L
G
K
R
L
G
Q
Y
V
E
V
A
ITYGGQPIGHTVGP
A
L
E
A
R
E
A
L
S
A
L
M
T
GKGP
G
S
L
I
E
K
A
T
G
L
A
G
I
L
L
E
M
G
GVAPAGT
G
K
K
M
A
K
E
I
L
E
S
G
K
A
W
E
K
M
K
E
I
I
E
A
Q
GGDPNIKPEEIPIGD
K
T
Y
T
F
T
AA
T
S
G
Y
VTAID
N
R
A
I
T
A
I
A
R
A
A
GAPEDKG
A
G
I
E
L
YVKVG
E
K
V
K
EGDPL
F
T
I
H
A
EH
E
A
R
L
D
Q
A
I
V
L
A
R
R
T
EPIRIE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
41.46
26%
15
- C4 -
3H2P
3
SODC_HUMAN
A:
[47-99]
---------------------------------------------------------------------------------------------------------------------------
V
H
E
F
G
--
D
-
N
T
A
G
C
T
S
A
G
P
H
F
N
P
--------------------------
R
HVGDL
G
N
V
T
A
D
K
D
-----
G
V
A
D
V
S
I
E
D
----
S
V
I
S
L
S
-
G
D
H
C
I
I
G
R
T
L
V
V
H
E
K
A
V
A
G
S
R
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
40.38
21%
29
- C3 -
4BUJ
3
SKI3_YEAST
B:
[3-1436]
DS
M
S
D
I
K
Q
L
L
K
E
A
K
Q
E
L
T
N
RD
Y
E
E
T
I
E
I
S
E
K
V
L
K
L
D
PDN
Y
F
A
H
I
F
L
G
K
A
L
S
S
LPASN
N
V
S
S
N
R
N
L
E
R
A
T
N
H
Y
V
S
A
A
K
L
V
PDN
L
L
A
W
K
G
L
F
L
L
F
R
T
T
E
V
V
P
D
I
L
S
Y
D
E
Y
F
D
L
C
G
Q
Y
A
D
A
L
L
K
Q
E
Q
V
E
L
I
--
N
-
D
I
K
L
L
K
K
T
H
P
D
C
Q
K
A
F
Y
Q
H
--------
L
K
P
G
S
------
L
M
A
--------
E
T
I
G
R
-----
T
P
Q
D
A
L
L
N
L
----
I
K
I
L
S
N
-
I
E
T
T
E
I
G
K
T
L
S
Q
N
R
L
K
L
K
A
S
D
P
D
Y
Q
I
K
L
N
S
F
S
W
E
I
I
K
N
SE
I
D
Q
L
Y
N
Q
L
V
N
I
LADD
Q
K
R
S
E
I
E
N
Q
W
L
E
Y
R
I
K
V
L
K
S
MP
L
D
V
K
K
D
F
F
T
K
V
K
E
M
V
E
D
M
V
L
V
NHQS
L
L
A
W
Q
K
Y
F
E
W
TDYEDLDNMDA
P
L
I
I
K
Y
F
K
K
FPKD
P
L
A
M
I
L
Y
S
W
L
S
SKLSKYD
I
K
S
L
E
SDDIEIGLL
E
E
E
V
V
T
V
L
T
E
N
I
V
K
C
KNN
I
L
A
H
R
I
L
C
Q
Y
Y
L
L
T
KEYEAA
L
P
Y
I
K
N
G
I
S
L
I
A
Y
N
I
K
D
LGVHL
P
L
T
K
R
E
F
S
L
D
L
A
T
V
Y
T
YVDAPKD
H
N
A
A
L
K
L
Y
D
N
I
L
S
GDFSN
I
Q
A
K
M
G
K
G
I
I
F
I
E
R
KNW
K
D
A
M
T
L
L
T
Q
V
H
E
Q
SPNN
L
E
V
L
S
E
L
S
W
S
K
A
H
M
GY
M
D
E
A
L
A
G
L
D
T
V
I
K
G
I
KGMD
L
R
S
I
D
F
R
A
L
N
L
W
R
Q
A
K
V
Y
I
M
K
H
A
SAKQE
N
V
K
C
A
F
K
L
L
I
Q
S
I
K
I
LDTF
A
P
G
F
S
T
L
G
D
I
Y
C
HYYKD
H
L
R
A
F
K
C
Y
F
K
A
F
D
L
DAGD
Y
T
A
A
K
Y
I
T
E
T
Y
A
S
K
PN
W
Q
A
A
S
S
I
A
S
R
L
I
K
G
EKA
K
A
E
L
R
S
NN
W
P
F
R
V
V
G
I
A
H
L
E
K
QE
E
S
D
S
I
E
W
F
Q
S
A
L
R
V
DPND
V
E
S
W
V
G
L
G
Q
A
Y
H
A
C
GR
I
E
A
S
I
K
V
F
D
K
A
I
Q
L
RPSH
T
F
A
Q
Y
F
K
A
I
S
L
C
D
V
GE
Y
L
E
S
L
D
I
L
E
K
V
C
Q
E
AATEE
S
F
Q
I
G
L
V
E
V
L
M
R
C
S
L
D
L
Y
S
Q
GF
L
L
K
S
V
S
I
A
K
D
T
I
E
R
I
K
I
I
I
S
E
LKCENQQ
V
W
I
Y
L
S
Q
V
L
R
L
F
I
W
I
ESKVDTLP
V
E
S
L
V
S
I
F
E
N
S
QFSGS
E
E
I
D
S
V
DNIKIDTLLDSTTDD
N
V
S
I
A
C
K
F
L
I
L
A
S
K
Y
SVSDQK
F
T
D
I
AG
T
V
R
A
S
Y
W
Y
N
I
G
I
S
E
L
T
A
F
I
T
L
KE
P
Q
Y
R
D
A
A
I
F
A
F
K
K
S
I
Q
L
QSNT
S
E
T
W
I
G
L
G
I
A
T
MDIN
F
R
V
S
Q
H
C
F
I
K
A
T
A
L
EPKA
T
N
T
W
F
N
L
A
M
L
G
L
K
K
KD
T
E
F
A
Q
Q
V
L
N
K
L
Q
S
L
APQD
S
S
P
W
L
G
M
A
L
I
L
E
E
Q
GD
I
I
G
S
S
K
L
F
A
H
S
F
I
L
S
N
GRS
K
A
A
Q
F
M
Y
A
K
N
V
L
E
N
HINNGDDERD
I
E
T
V
E
K
L
T
T
A
S
I
A
L
E
Q
F
F
K
K
SPDS
Q
F
A
L
Q
C
A
L
L
T
L
E
R
L
HH
Y
E
N
A
N
E
L
A
N
R
L
I
G
I
L
E
K
K
F
E
K
TQD
E
R
E
L
F
N
F
A
I
I
K
G
Q
F
A
R
I
H
L
G
L
GN
F
E
L
S
I
E
N
A
D
L
S
Q
G
I
I
SESSD
E
K
S
M
K
T
K
I
S
N
H
I
C
L
G
L
S
Y
F
F
L
NDF
D
Q
T
L
N
Q
F
Q
E
L
L
S
I
S
KDS
K
H
L
V
V
L
I
A
K
V
L
Y
D
V
GE
S
D
T
K
E
I
A
L
Q
E
L
T
E
Y
I
A
T
SGADL
L
V
T
L
T
I
A
A
M
S
I
L
D
DK
R
E
D
L
S
I
I
L
E
E
L
K
A
LP
L
S
K
Q
I
I
DKHK
D
A
P
Y
L
I
E
E
I
T
K
R
L
YRNDTGK
Q
V
W
Q
R
S
A
Y
F
FPNN
L
K
V
W
E
R
LD
K
N
I
Q
R
R
I
A
SNGQ
N
K
V
T
A
E
E
M
S
K
L
Y
C
E
S
KN
L
R
S
I
Q
R
G
M
F
L
C
PWN
V
T
A
V
K
A
L
N
E
C
F
5
PsiBlast_PDB
40.06
28%
-0
- C4 -
3CQP
4
SODC_HUMAN
A:
[47-99]
---------------------------------------------------------------------------------------------------------------------------
V
H
E
F
G
--
D
-
N
T
A
G
C
T
S
A
G
P
H
F
N
P
L
S
R
K
H
--------
G
G
P
K
D
E
E
R
H
VG
D
L
R
N
V
------
T
A
D
K
D
-----
G
V
A
D
V
S
I
E
D
----
S
V
I
S
L
S
-
G
D
H
C
I
I
G
R
T
L
V
V
H
E
K
A
D
D
L
G
K
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
39.30
26%
10
- C4 -
3H2Q
2
SODC_HUMAN
A:
[47-99]
---------------------------------------------------------------------------------------------------------------------------
V
H
E
F
G
--
D
-
N
T
A
G
C
T
S
A
G
P
H
F
N
P
--------------------------
R
RVGDL
G
N
V
T
A
D
K
D
-----
G
V
A
D
V
S
I
E
D
----
S
V
I
S
L
S
-
G
D
H
C
I
I
G
R
T
L
V
V
H
E
K
A
D
D
L
G
K
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
Fugue
38.37
15%
39
- C3 -
3CL3
-
NEMO_HUMAN
D:
[193-251]
-----------------------------------------------------------------------------------------------------------------------------------------
Q
Q
H
S
V
Q
V
D
Q
L
R
M
Q
G
--------
Q
S
V
E
A
------
A
L
R
--------
M
E
R
Q
A
-----
A
S
E
E
----------
K
R
K
L
A
-
Q
L
Q
V
A
Y
H
Q
L
F
Q
E
Y
D
N
H
I
K
S
S
V
V
G----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
38.24
28%
8
- C4 -
2ZKX
2
SODC_HUMAN
A:
[53-105]
---------------------------------------------------------------------------------------------------------------------------
V
H
E
F
G
--
D
-
N
T
A
G
C
T
S
A
G
P
H
F
N
P
L
S
R
K
H
--------
G
G
P
K
D
EERHVG
D
L
R
N
V
------
T
A
D
K
D
-----
G
V
A
D
V
S
I
E
D
----
S
V
I
S
L
S
-
G
D
H
C
I
I
G
R
T
L
V
V
H
E
K
A
D
D
L
G
K
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
38.11
28%
-5
- C4 -
2ZKW
2
SODC_HUMAN
A:
[53-105]
---------------------------------------------------------------------------------------------------------------------------
V
H
E
F
G
--
D
-
N
T
A
G
C
T
S
A
G
P
H
F
N
P
L
S
R
K
H
--------
G
G
P
K
D
EERHVG
D
L
R
N
V
------
T
A
D
K
D
-----
G
V
A
D
V
S
I
E
D
----
S
V
I
S
L
S
-
G
D
H
C
I
I
G
R
T
L
V
V
H
E
K
A
D
D
L
G
K
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------