@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_1201: (2015-12-21 )
MKDILNALYHQKDLNDEEVKKLFTLIIDEKVSPAQLGAVLCALKIKGESFKEISVAATTLLEHAPKPFNSGLDLIDNCGTGGDGLKTINISTIAALIASSMGLSMAKHGSRSVSSHSGSADLLENLGVNIEMNPMQLENCFKQSHFGFLFAPLYHQSFKKSAPLRKELFTKTIFNCLGPLINPLRPKIQLLGVYDKSLCKTMALALKALGVKRAMVVNGGGTDEIVLHDITHACELKNNEILEYDLSAKDFDLPPYDLKELQIENAKESVQACLDILENKGKDSHTMVVAANVASLLYLSHRAKDLKEGVSMTLEHLKTKAPYAHLQKIIRLSHA
Atome Classification :
(26 SA)
-.........10........20........30........40........50........60...-....-.--70...-.---.....80........90........100.......110....-...120.......130.......140.......150.......160.......170.......180.......190.......200.......210..--.....-220.......230.......240.-----......250.......260.......----270.......-280-..---....-..290.......300..--..---...310.......320.......330...
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-
M
K
D
I
L
N
A
L
Y
HQKDL
N
D
E
E
V
K
K
L
F
T
L
I
IDEKV
S
P
A
Q
L
G
A
V
L
C
A
L
K
IKGESF
K
E
I
S
V
A
A
T
T
L
L
E
HA-PKPF-N--S-GL
D
-
L
---
I
DNCGTGGDG
L
K
T
I
N
I
S
T
I
A
A
L
I
A
S
S
MG
L
S
M
A
KHGSRSVSSH-SG
S
A
D
L
L
E
NLGV
N
I
E
M
N
P
M
Q
L
E
N
C
F
K
QSHF
G
F
L
F
A
P
L
Y
H
Q
S
F
KKSA
P
L
R
K
E
L
F
T
K
T
I
F
N
C
L
G
P
L
I
NPLRP
K
I
Q
L
L
G
V
Y
D
K
S
L
C
K
T
M
A
L
A
L
K
A
LGV
K
R
A
--
M
V
V
NG-GGT
D
E
I
V
L
HDI
T
H
A
CELKNN
E
I
L
E
-----
Y
DLSAKDFDLPPY
D
L
K
E
L
Q
I
E
N
A
K
E
S
----
V
Q
A
C
L
D
I
L
EN-KG--KD---S
H
T
M
-
V
V
A
A
N
V
A
S
L
L
Y
L
S
H
R
A
K
--
D
L
---
K
E
G
V
S
M
T
L
E
H
L
KTKA
P
Y
A
H
L
Q
K
I
I
R
LSHA
49
HHSearch
95.32
40%
-111
- C2 -
1KHD
-
?
A:
[13-344]
-
H
Q
P
I
L
E
K
L
F
K
S
Q
S
M
T
Q
E
E
S
H
Q
L
F
A
A
I
V
R
G
E
L
E
D
S
Q
L
A
A
A
L
I
S
M
K
M
R
G
E
R
P
E
E
I
A
G
A
A
S
A
L
L
A
D
A
-
Q
P
-
F
-
P
R-
P
-
D
Y
D
-
F
---
A
D
I
V
G
T
G
G
D
G
T
N
S
I
N
I
S
T
A
S
A
F
V
A
A
S
C
G
A
K
V
A
K
H
G
N
R
---------
C
D
L
L
Q
A
F
G
I
R
L
D
M
S
A
E
D
S
R
Q
A
L
D
D
L
N
V
C
F
L
F
A
P
Q
Y
H
T
G
F
R
H
A
M
P
V
R
Q
Q
L
K
T
R
T
I
F
N
V
L
G
P
L
I
N
P
A
R
P
P
K
A
L
I
G
V
Y
S
P
E
L
V
L
P
I
A
Q
A
L
K
V
L
G
Y
K
N
A
--
A
V
V
H
G
-
G
G
M
D
E
V
A
I
H
T
P
T
Q
V
A
E
L
N
N
G
E
I
E
S
-----
Y
Q
L
S
P
Q
D
F
G
L
Q
S
Y
S
L
N
A
L
Q
G
G
T
P
E
E
N
----
R
D
I
L
A
R
L
L
Q
G
-
K
G
--
D
A
---
A
H
A
R
-
Q
V
A
A
N
V
A
L
L
L
K
L
F
G
Q
D
---
N
L
---
R
H
N
A
Q
L
A
L
E
T
I
R
S
G
T
A
F
E
R
V
T
A
L
A
A
R
---
1
PsiBlast_PDB
94.49
41%
-103
- C2 -
1KGZ
4
?
A:
[14-335]
--
Q
P
I
L
E
K
L
F
K
S
Q
S
M
T
Q
E
E
S
H
Q
L
F
A
A
I
V
R
G
E
L
E
D
S
Q
L
A
A
A
L
I
S
M
K
M
R
G
E
R
P
E
E
I
A
G
A
A
S
A
L
L
A
D
A
--
Q
P
F
P
R
--
P
-
D
Y
D
-
F
---
A
D
I
V
G
T
G
G
D
G
T
N
S
I
N
I
S
T
A
S
A
F
V
A
A
S
C
G
A
K
V
A
K
H
G
N
R
S
-----
A
G
S
C
D
L
L
Q
A
F
G
I
R
L
D
M
S
A
E
D
S
R
Q
A
L
D
D
L
N
V
C
F
L
F
A
P
Q
Y
H
T
G
F
R
H
A
M
P
V
R
Q
Q
L
K
T
R
T
I
F
N
V
L
G
P
L
I
N
P
A
R
P
P
K
A
L
I
G
V
Y
S
P
E
L
V
L
P
I
A
Q
A
L
K
V
L
G
Y
K
N
A
--
A
V
V
H
G
-
G
G
M
D
E
V
A
I
H
T
P
T
Q
V
A
E
L
N
N
G
E
I
E
S
-----
Y
Q
L
S
P
Q
D
F
G
L
Q
S
Y
S
L
N
A
L
Q
G
G
T
P
E
E
N
----
R
D
I
L
A
R
L
L
Q
G
-
K
G
--
D
A
---
A
H
A
R
-
Q
V
A
A
N
V
A
L
L
L
K
L
F
G
Q
-
D
--
N
L
---
R
H
N
A
Q
L
A
L
E
T
I
R
S
G
T
A
F
E
R
V
T
A
L
A
A
R
---
38
Fugue
94.27
39%
-109
- C2 -
1KHD
-
?
A:
[12-344]
T
H
Q
P
I
L
E
K
L
F
K
S
Q
S
M
T
Q
E
E
S
H
Q
L
F
A
A
I
V
R
G
E
L
E
D
S
Q
L
A
A
A
L
I
S
M
K
M
R
G
E
R
P
E
E
I
A
G
A
A
S
A
L
L
A
D
A
-
Q
P
F
P
-
R
--
P
-
D
Y
D
-
F
---
A
D
I
V
G
T
G
G
D
G
T
N
S
I
N
I
S
T
A
S
A
F
V
A
A
S
C
G
A
K
V
A
K
H
G
N
R
---------
C
D
L
L
Q
A
F
G
I
R
L
D
M
S
A
E
D
S
R
Q
A
L
D
D
L
N
V
C
F
L
F
A
P
Q
Y
H
T
G
F
R
H
A
M
P
V
R
Q
Q
L
K
T
R
T
I
F
N
V
L
G
P
L
I
N
P
A
R
P
P
K
A
L
I
G
V
Y
S
P
E
L
V
L
P
I
A
Q
A
L
K
V
L
G
Y
K
N
A
--
A
V
V
H
G
-
G
G
M
D
E
V
A
I
H
T
P
T
Q
V
A
E
L
N
N
G
E
I
E
S
-----
Y
Q
L
S
P
Q
D
F
G
L
Q
S
Y
S
L
N
A
L
Q
G
G
T
P
E
E
N
----
R
D
I
L
A
R
L
L
Q
G
-
K
G
--
D
A
---
A
H
A
R
-
Q
V
A
A
N
V
A
L
L
L
K
L
F
G
-
Q
D
--
N
L
---
R
H
N
A
Q
L
A
L
E
T
I
R
S
G
T
A
F
E
R
V
T
A
L
A
A
R
---
21
PsiBlast_CBE
94.06
41%
-103
- C2 -
1KGZ
4
?
B:
[14-335]
--
Q
P
I
L
E
K
L
F
K
S
Q
S
M
T
Q
E
E
S
H
Q
L
F
A
A
I
V
R
G
E
L
E
D
S
Q
L
A
A
A
L
I
S
M
K
M
R
G
E
R
P
E
E
I
A
G
A
A
S
A
L
L
A
D
A
--
Q
P
F
P
R
--
P
-
D
Y
D
-
F
---
A
D
I
V
G
T
G
G
D
G
T
N
S
I
N
I
S
T
A
S
A
F
V
A
A
S
C
G
A
K
V
A
K
H
G
N
R
S
V
---L
A
G
S
C
D
L
L
Q
A
F
G
I
R
L
D
M
S
A
E
D
S
R
Q
A
L
D
D
L
N
V
C
F
L
F
A
P
Q
Y
H
T
G
F
R
H
A
M
P
V
R
Q
Q
L
K
T
R
T
I
F
N
V
L
G
P
L
I
N
P
A
R
P
P
K
A
L
I
G
V
Y
S
P
E
L
V
L
P
I
A
Q
A
L
K
V
L
G
Y
K
N
A
--
A
V
V
H
G
-
G
G
M
D
E
V
A
I
H
T
P
T
Q
V
A
E
L
N
N
G
E
I
E
S
-----
Y
Q
L
S
P
Q
D
F
G
L
Q
S
Y
S
L
N
A
L
Q
G
G
T
P
E
E
N
----
R
D
I
L
A
R
L
L
Q
G
-
K
G
--
D
A
---
A
H
A
R
-
Q
V
A
A
N
V
A
L
L
L
K
L
F
G
Q
-
D
--
N
L
---
R
H
N
A
Q
L
A
L
E
T
I
R
S
G
T
A
F
E
R
V
T
A
L
A
A
R
---
2
PsiBlast_PDB
93.57
41%
-107
- C2 -
1KHD
-
?
A:
[14-335]
--
Q
P
I
L
E
K
L
F
K
S
Q
S
M
T
Q
E
E
S
H
Q
L
F
A
A
I
V
R
G
E
L
E
D
S
Q
L
A
A
A
L
I
S
M
K
M
R
G
E
R
P
E
E
I
A
G
A
A
S
A
L
L
A
D
A
--
Q
P
F
P
R
--
P
-
D
Y
D
-
F
---
A
D
I
V
G
T
G
G
D
G
T
N
S
I
N
I
S
T
A
S
A
F
V
A
A
S
C
G
A
K
V
A
K
H
G
N
R
---------
C
D
L
L
Q
A
F
G
I
R
L
D
M
S
A
E
D
S
R
Q
A
L
D
D
L
N
V
C
F
L
F
A
P
Q
Y
H
T
G
F
R
H
A
M
P
V
R
Q
Q
L
K
T
R
T
I
F
N
V
L
G
P
L
I
N
P
A
R
P
P
K
A
L
I
G
V
Y
S
P
E
L
V
L
P
I
A
Q
A
L
K
V
L
G
Y
K
N
A
--
A
V
V
H
G
-
G
G
M
D
E
V
A
I
H
T
P
T
Q
V
A
E
L
N
N
G
E
I
E
S
-----
Y
Q
L
S
P
Q
D
F
G
L
Q
S
Y
S
L
N
A
L
Q
G
G
T
P
E
E
N
----
R
D
I
L
A
R
L
L
Q
G
-
K
G
--
D
A
---
A
H
A
R
-
Q
V
A
A
N
V
A
L
L
L
K
L
F
G
Q
-
D
--
N
L
---
R
H
N
A
Q
L
A
L
E
T
I
R
S
G
T
A
F
E
R
V
T
A
L
A
A
R
---
48
HHSearch
91.82
35%
-97
- C2 -
1VQU
2
TRPD2_NOSS1
A:
[27-374]
-
W
Y
L
L
L
Q
Q
L
I
D
G
E
S
L
S
R
S
Q
A
A
E
L
M
Q
G
W
L
S
E
A
V
P
P
E
L
S
G
A
I
L
T
A
L
N
F
K
G
V
S
A
D
E
L
T
G
M
A
E
V
L
Q
S
Q
S
-
K
M
----TN
S
-
P
F
S
-
I
---
I
D
T
C
G
T
G
---
S
S
T
F
N
I
S
T
A
V
A
F
V
A
A
A
Y
G
V
P
V
A
K
H
G
N
R
--
S
S
L
-
T
G
S
A
D
V
L
E
A
L
G
V
N
L
G
A
S
P
E
K
V
Q
A
A
L
Q
E
V
G
I
T
F
L
F
A
P
G
W
H
P
A
L
K
A
V
A
T
L
R
R
T
L
R
I
R
T
V
F
N
L
L
G
P
L
V
N
P
L
R
P
T
G
Q
V
V
G
L
F
T
P
K
L
L
T
T
V
A
Q
A
L
D
N
L
G
K
Q
K
A
--
I
V
L
H
G
R
E
R
L
D
E
A
G
L
G
D
L
T
D
L
A
V
L
S
D
G
E
L
Q
L
-----
T
T
I
N
P
Q
E
V
G
V
T
P
A
P
I
G
A
L
R
G
G
D
V
Q
E
N
----
A
E
I
L
K
A
V
L
Q
G
-
K
G
--
T
Q
---
A
Q
Q
D
-
A
V
A
L
N
A
A
L
A
L
Q
V
A
G
A
V
P
LL
D
H
---
A
Q
G
V
S
V
A
K
E
I
L
Q
T
G
T
A
W
A
K
L
A
Q
L
V
Y
F
L
G
N
51
HHSearch
88.71
34%
-114
* C2 *
1O17
-
TRPD_SULSO
A:
[3-332]
-
I
N
E
I
L
K
K
L
I
N
K
S
D
L
E
I
N
E
A
E
E
L
A
K
A
I
I
R
G
E
V
P
E
I
L
V
S
A
I
L
V
A
L
R
M
K
G
E
S
K
N
E
I
V
G
F
A
R
A
M
R
E
L
A
-
I
K
-
I
-
D
--
V
--
P
N
-
A
---
I
D
T
A
G
----
G
L
G
T
V
N
V
S
T
A
S
A
I
L
L
S
-
L
V
N
P
V
A
K
H
G
N
R
A
V
S
G
K
-
S
G
S
A
D
V
L
E
A
L
G
Y
N
I
I
V
P
P
E
R
A
K
E
L
V
N
K
T
N
F
V
F
L
F
A
Q
Y
Y
H
P
A
M
K
N
V
A
N
V
R
K
T
L
G
I
R
T
I
F
N
I
L
G
P
L
T
N
P
A
N
A
K
Y
Q
L
M
G
V
F
S
K
D
H
L
D
L
L
S
K
S
A
Y
E
L
D
F
N
K
I
--
I
L
V
Y
G
E
P
G
I
D
E
V
S
P
I
G
N
T
F
M
K
I
V
S
K
R
G
I
E
E
-----
V
K
L
N
V
T
D
F
G
I
S
P
I
P
I
E
K
L
I
V
N
S
A
E
D
S
----
A
I
K
I
V
R
A
F
L
G
-
K
---
D
E
---
H
V
A
E
-
F
I
K
I
N
T
A
V
A
L
F
A
L
D
R
V
G
--
D
F
---
R
E
G
Y
E
Y
A
D
H
L
I
E
--
K
S
L
D
K
L
N
E
I
I
S
M
N
G
D
50
HHSearch
88.32
34%
-102
- C2 -
2ELC
4
TRPD_THET8
A:
[2-328]
---
D
A
V
K
K
A
I
L
G
E
V
L
E
E
E
E
A
Y
E
V
M
R
A
L
M
A
G
E
V
S
P
V
R
A
A
G
L
L
V
A
L
S
L
R
G
E
R
P
H
E
I
A
A
M
A
R
A
M
R
E
A
A
-
R
P
-
L
-
R
V
-
H
-
R
R
P
-
L
---
L
D
I
V
G
T
G
G
D
G
K
G
L
M
N
L
S
T
L
A
A
L
V
A
A
A
G
G
V
A
V
A
K
H
G
N
R
A
A
S
S
R
-
A
G
S
A
D
L
L
E
A
L
G
V
D
L
E
A
P
P
E
R
V
G
E
A
I
E
E
L
G
F
G
F
L
F
A
R
V
F
H
P
A
M
R
H
V
A
P
V
R
A
E
L
G
V
R
T
V
F
N
L
L
G
P
L
T
N
P
A
G
A
D
A
Y
V
L
G
V
F
S
P
E
W
L
A
P
M
A
E
A
L
E
R
L
G
A
-
R
G
--
L
V
V
H
G
-
E
G
A
D
E
L
V
L
-
G
E
N
R
V
V
E
V
G
K
G
---
A
-----
Y
A
L
T
P
E
E
V
G
L
K
R
A
P
L
E
A
L
K
G
G
G
P
E
E
N
----
A
A
L
A
R
R
L
L
K
G
-
E
E
--
K
G
---
P
L
A
D
-
A
V
A
L
A
A
G
A
G
F
Y
A
A
G
K
T
P
--
S
L
---
K
E
G
V
A
L
A
R
E
V
L
A
S
G
E
A
Y
L
L
L
E
R
Y
V
A
F
L
R
A
32
PsiBlast_CBE
87.00
36%
-108
- C2 -
1GXB
2
TRPD_SULSO
C:
[3-319]
-
I
N
E
I
L
K
K
L
I
N
K
S
D
L
E
I
N
E
A
E
E
L
A
K
A
I
I
R
G
E
V
P
E
I
L
V
S
A
I
L
V
A
L
R
M
K
G
E
S
K
N
E
I
V
G
F
A
R
A
M
R
E
L
A
-
I
K
---------
I
D
-
V
PN
A
I
D
T
A
G
----
G
L
G
T
V
N
V
S
T
A
S
A
I
L
L
S
L
V
N
-
P
V
A
K
H
G
N
R
A
V
S
G
K
-
S
G
S
A
D
V
L
E
A
L
G
Y
N
I
I
V
P
P
E
R
A
K
E
L
V
N
K
T
N
F
V
F
L
F
A
Q
Y
Y
H
P
A
M
K
N
V
A
N
V
R
K
T
L
G
I
R
T
I
F
N
I
L
G
P
L
T
N
P
A
N
A
K
Y
Q
L
M
G
V
F
S
K
D
H
L
D
L
L
S
K
S
A
Y
E
L
D
F
N
K
I
--
I
L
V
Y
G
E
P
G
I
D
E
V
S
P
I
G
N
T
F
M
K
I
V
S
K
R
G
I
E
E
-----
V
K
L
N
V
T
D
F
G
I
S
P
I
P
I
E
K
L
I
V
N
S
A
E
D
S
A
I
K
I
V
R
A
F
L
-------
G
--
K
D
---
E
H
V
A
E
F
I
K
I
N
T
A
V
A
L
F
A
L
D
R
V
G
--
D
F
---
R
E
G
Y
E
Y
A
-
D
H
L
I
E
K
S
L
D
K
L
N
E
I
I
S
M
N
G
D
V
6
PsiBlast_PDB
86.76
36%
-107
- C2 -
1GXB
2
TRPD_SULSO
A:
[3-319]
-
I
N
E
I
L
K
K
L
I
N
K
S
D
L
E
I
N
E
A
E
E
L
A
K
A
I
I
R
G
E
V
P
E
I
L
V
S
A
I
L
V
A
L
R
M
K
G
E
S
K
N
E
I
V
G
F
A
R
A
M
R
E
L
A
-
I
K
---------
I
D
-
V
PNA
I
D
T
A
G
----
G
L
G
T
V
N
V
S
T
A
S
A
I
L
L
S
L
V
N
-
P
V
A
K
H
G
N
R
A
V
S
G
K
-
S
G
S
A
D
V
L
E
A
L
G
Y
N
I
I
V
P
P
E
R
A
K
E
L
V
N
K
T
N
F
V
F
L
F
A
Q
Y
Y
H
P
A
M
K
N
V
A
N
V
R
K
T
L
G
I
R
T
I
F
N
I
L
G
P
L
T
N
P
A
N
A
K
Y
Q
L
M
G
V
F
S
K
D
H
L
D
L
L
S
K
S
A
Y
E
L
D
F
N
K
I
--
I
L
V
Y
G
E
P
G
I
D
E
V
S
P
I
G
N
T
F
M
K
I
V
S
K
R
G
I
E
E
-----
V
K
L
N
V
T
D
F
G
I
S
P
I
P
I
E
K
L
I
V
N
S
A
E
D
S
A
I
K
I
V
R
A
F
L
-------
G
--
K
D
---
E
H
V
A
E
F
I
K
I
N
T
A
V
A
L
F
A
L
D
R
V
G
--
D
F
---
R
E
G
Y
E
Y
A
-
D
H
L
I
E
K
S
L
D
K
L
N
E
I
I
S
M
N
G
D
V
5
PsiBlast_PDB
86.75
36%
-109
- C2 -
1O17
-
TRPD_SULSO
A:
[3-319]
-
I
N
E
I
L
K
K
L
I
N
K
S
D
L
E
I
N
E
A
E
E
L
A
K
A
I
I
R
G
E
V
P
E
I
L
V
S
A
I
L
V
A
L
R
M
K
G
E
S
K
N
E
I
V
G
F
A
R
A
M
R
E
L
A
-
I
K
---------
I
D
-
V
PN
A
I
D
T
A
G
----
G
L
G
T
V
N
V
S
T
A
S
A
I
L
L
S
L
V
N
-
P
V
A
K
H
G
N
R
A
V
S
G
K
-
S
G
S
A
D
V
L
E
A
L
G
Y
N
I
I
V
P
P
E
R
A
K
E
L
V
N
K
T
N
F
V
F
L
F
A
Q
Y
Y
H
P
A
M
K
N
V
A
N
V
R
K
T
L
G
I
R
T
I
F
N
I
L
G
P
L
T
N
P
A
N
A
K
Y
Q
L
M
G
V
F
S
K
D
H
L
D
L
L
S
K
S
A
Y
E
L
D
F
N
K
I
--
I
L
V
Y
G
E
P
G
I
D
E
V
S
P
I
G
N
T
F
M
K
I
V
S
K
R
G
I
E
E
-----
V
K
L
N
V
T
D
F
G
I
S
P
I
P
I
E
K
L
I
V
N
S
A
E
D
S
A
I
K
I
V
R
A
F
L
-------
G
--
K
D
---
E
H
V
A
E
F
I
K
I
N
T
A
V
A
L
F
A
L
D
R
V
G
--
D
F
---
R
E
G
Y
E
Y
A
-
D
H
L
I
E
K
S
L
D
K
L
N
E
I
I
S
M
N
G
D
V
27
PsiBlast_CBE
86.55
36%
-101
- C2 -
1ZYK
5
TRPD_SULSO
B:
[3-319]
-
I
N
E
I
L
K
K
L
I
N
K
S
D
L
E
I
N
E
A
E
E
L
A
K
A
I
I
R
G
E
V
P
E
I
L
V
S
A
I
L
V
A
L
R
M
K
G
E
S
K
N
E
I
V
G
F
A
R
A
M
R
E
L
A
-
I
K
---------
I
D
-
V
PNA
I
D
T
A
G
T
G
G
D
G
L
G
T
V
N
V
S
T
A
S
A
I
L
L
S
L
V
N
-
P
V
A
K
H
G
N
R
A
V
S
G
K
-
S
G
S
A
D
V
L
E
A
L
G
Y
N
I
I
V
P
P
E
R
A
K
E
L
V
N
K
T
N
F
V
F
L
F
A
Q
Y
Y
H
P
A
M
K
N
V
A
N
V
R
K
T
L
G
I
R
T
I
F
N
I
L
G
P
L
T
N
P
A
N
A
K
Y
Q
L
M
G
V
F
S
K
D
H
L
D
L
L
S
K
S
A
Y
E
L
D
F
N
K
I
--
I
L
V
Y
G
E
P
G
I
D
E
V
S
P
I
G
N
T
F
M
K
I
V
S
K
R
G
I
E
E
-----
V
K
L
N
V
T
D
F
G
I
S
P
I
P
I
E
K
L
I
V
N
S
A
E
D
S
AIKI
V
R
A
F
L
-------
G
--
K
D
---
E
H
V
A
E
F
I
K
I
N
T
A
V
A
L
F
A
L
D
R
V
G
--
D
F
---
R
E
G
Y
E
Y
A
-
D
H
L
I
E
K
S
L
D
K
L
N
E
I
I
S
M
N
G
D
V
8
PsiBlast_PDB
86.29
36%
-101
- C2 -
1ZYK
5
TRPD_SULSO
A:
[3-319]
-
I
N
E
I
L
K
K
L
I
N
K
S
D
L
E
I
N
E
A
E
E
L
A
K
A
I
I
R
G
E
V
P
E
I
L
V
S
A
I
L
V
A
L
R
M
K
G
E
S
K
N
E
I
V
G
F
A
R
A
M
R
E
L
A
-
I
K
---------
I
D
-
V
PNA
I
D
T
A
G
T
G
G
D
G
L
G
T
V
N
V
S
T
A
S
A
I
L
L
S
L
V
N
-
P
V
A
K
H
G
N
R
A
V
S
G
K
-
S
G
S
A
D
V
L
E
A
L
G
Y
N
I
I
V
P
P
E
R
A
K
E
L
V
N
K
T
N
F
V
F
L
F
A
Q
Y
Y
H
P
A
M
K
N
V
A
N
V
R
K
T
L
G
I
R
T
I
F
N
I
L
G
P
L
T
N
P
A
N
A
K
Y
Q
L
M
G
V
F
S
K
D
H
L
D
L
L
S
K
S
A
Y
E
L
D
F
N
K
I
--
I
L
V
Y
G
E
P
G
I
D
E
V
S
P
I
G
N
T
F
M
K
I
V
S
K
R
G
I
E
E
-----
V
K
L
N
V
T
D
F
G
I
S
P
I
P
I
E
K
L
I
V
N
S
A
E
D
S
A
I
K
I
V
R
A
F
L
-------
G
--
K
D
---
E
H
V
A
E
F
I
K
I
N
T
A
V
A
L
F
A
L
D
R
V
G
--
D
F
---
R
E
G
Y
E
Y
A
-
D
H
L
I
E
K
S
L
D
K
L
N
E
I
I
S
M
N
G
D
V
18
PsiBlast_PDB
86.16
30%
-91
- C2 -
3QR9
2
TRPD_MYCTU
A:
[29-367]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
-
D
--
T
V
P
D
D
-
A
---
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
-
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
---
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
-----
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
----
A
A
A
V
R
A
V
L
G
G
A
R
G
P
V
R
D
---
A
V
V
L
-
N
A
A
G
A
I
V
A
H
A
G
L
S
S
R
A
E
--
W
L
P
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
19
PsiBlast_PDB
86.13
30%
-91
- C2 -
3QQS
4
TRPD_MYCTU
A:
[29-367]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
-
D
--
T
V
P
D
D
-
A
---
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
-
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
---
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
-----
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
----
A
A
A
V
R
A
V
L
G
G
A
R
G
P
V
R
D
---
A
V
V
L
-
N
A
A
G
A
I
V
A
H
A
G
L
S
S
R
A
E
--
W
L
P
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
33
PsiBlast_CBE
86.11
36%
-106
- C2 -
1GXB
1
TRPD_SULSO
B:
[3-319]
-
I
N
E
I
L
K
K
L
I
N
K
S
D
L
E
I
N
E
A
E
E
L
A
K
A
I
I
R
G
E
V
P
E
I
L
V
S
A
I
L
V
A
L
R
M
K
G
E
S
K
N
E
I
V
G
F
A
R
A
M
R
E
L
A
-
I
K
---------
I
D
-
V
PN
A
I
D
T
A
G
---
D
G
L
G
T
V
N
V
S
T
A
S
A
I
L
L
S
L
V
N
-
P
V
A
K
H
G
N
R
A
V
S
G
K
-
S
G
S
A
D
V
L
E
A
L
G
Y
N
I
I
V
P
P
E
R
A
K
E
L
V
N
K
T
N
F
V
F
L
F
A
Q
Y
Y
H
P
A
M
K
N
V
A
N
V
R
K
T
L
G
I
R
T
I
F
N
I
L
G
P
L
T
N
P
A
N
A
K
Y
Q
L
M
G
V
F
S
K
D
H
L
D
L
L
S
K
S
A
Y
E
L
D
F
N
K
I
--
I
L
V
Y
G
E
P
G
I
D
E
V
S
P
I
G
N
T
F
M
K
I
V
S
K
R
G
I
E
E
-----
V
K
L
N
V
T
D
F
G
I
S
P
I
P
I
E
K
L
I
V
N
S
A
E
D
S
A
I
K
I
V
R
A
F
L
-------
G
--
K
D
---
E
H
V
A
E
F
I
K
I
N
T
A
V
A
L
F
A
L
D
R
V
G
--
D
F
---
R
E
G
Y
E
Y
A
-
D
H
L
I
E
K
S
L
D
K
L
N
E
I
I
S
M
N
G
D
V
3
PsiBlast_PDB
85.98
36%
-109
- C2 -
4YI7
1
?
A:
[19-335]
-
I
Q
Q
A
L
N
H
I
T
K
N
I
H
L
T
Q
A
Q
M
E
D
V
M
R
S
I
M
Q
G
E
A
T
E
A
Q
I
G
A
L
M
M
G
L
R
M
K
G
E
S
I
D
E
I
T
A
A
A
R
V
M
R
E
L
A
-
I
K
I
D
-
V
--
S
-
D
I
Q
Y
L
---
V
D
I
V
G
T
G
G
D
--
N
L
F
N
V
S
T
A
S
S
F
V
I
A
A
A
G
A
T
I
A
K
H
G
N
R
--------
S
S
D
L
L
E
Q
A
G
I
N
L
D
L
D
M
Q
Q
T
E
R
C
I
R
E
M
G
V
G
F
L
F
A
------
M
K
Y
A
V
G
P
R
R
E
L
G
I
R
S
I
F
N
L
L
G
P
L
T
N
P
A
G
V
K
R
F
V
I
G
V
F
S
D
E
L
C
R
P
I
A
E
V
M
K
Q
L
G
A
E
H
V
--
M
V
V
H
S
K
D
G
L
D
E
I
S
L
A
S
Q
T
Y
I
A
E
L
K
N
G
E
V
T
E
-----
W
V
L
N
P
E
D
V
N
I
P
S
Q
T
L
S
G
L
I
V
E
D
S
N
A
S
----
L
K
L
I
K
D
A
L
G
R
-
K
K
--
S
D
I
G
E
K
A
A
N
-
M
I
A
L
N
A
G
A
G
I
Y
V
S
G
L
A
T
--
S
Y
---
K
Q
G
V
A
L
A
H
D
I
I
Y
G
G
Q
A
L
E
K
M
S
I
L
S
E
F
T
K
A
20
PsiBlast_PDB
85.93
30%
-93
- C2 -
3QS8
5
TRPD_MYCTU
A:
[29-367]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
-
D
--
T
V
P
D
D
-
A
---
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
-
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
---
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
-----
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
----
A
A
A
V
R
A
V
L
G
G
A
R
G
P
V
R
D
---
A
V
V
L
-
N
A
A
G
A
I
V
A
H
A
G
L
S
S
R
A
E
--
W
L
P
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
37
PsiBlast_CBE
85.77
35%
-104
- C2 -
3GBR
7
TRPD_SULSO
B:
[3-319]
-
I
N
E
I
L
K
K
L
I
N
K
S
D
L
E
I
N
E
A
E
E
L
A
K
A
I
I
R
G
E
V
P
E
I
L
V
S
A
I
L
V
A
L
R
M
K
G
E
S
K
N
E
I
V
G
F
A
R
A
M
R
E
L
A
-
I
K
---------
I
D
-
V
PN
A
I
D
T
A
G
T
G
G
G
G
L
G
T
V
N
V
S
T
A
S
A
I
L
L
S
L
V
N
-
P
V
A
K
H
G
N
R
A
V
S
G
K
-
S
G
S
A
D
V
L
E
A
L
G
Y
N
I
I
V
P
P
E
R
A
K
E
L
V
N
K
T
N
F
V
F
L
S
A
Q
Y
Y
H
P
A
M
K
N
V
A
N
V
R
K
T
L
G
I
R
T
I
F
N
I
L
G
P
L
T
N
P
A
N
A
K
Y
Q
L
M
G
V
F
S
K
D
H
L
D
L
L
S
K
S
A
Y
E
L
D
F
N
K
I
--
I
L
V
Y
G
E
P
G
I
D
E
V
S
P
I
G
N
T
F
M
K
I
V
S
K
R
G
I
E
E
-----
V
K
L
N
V
T
D
F
G
I
S
P
I
P
I
E
K
L
I
V
N
S
A
E
D
S
A
I
K
I
V
R
A
F
L
-------
G
--
K
D
---
E
H
V
A
E
F
I
K
I
N
T
A
V
A
L
F
A
L
D
R
V
G
--
D
F
---
R
E
G
Y
E
Y
A
-
D
H
L
I
E
K
S
L
D
K
L
N
E
I
I
S
M
N
G
D
V
16
PsiBlast_PDB
85.75
30%
-93
- C2 -
4GKM
8
TRPD_MYCTU
A:
[31-369]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
-
D
--
T
V
P
D
D
-
A
---
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
-
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
---
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
-----
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
----
A
A
A
V
R
A
V
L
G
G
A
R
G
P
V
R
D
---
A
V
V
L
-
N
A
A
G
A
I
V
A
H
A
G
L
S
S
R
A
E
--
W
L
P
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
15
PsiBlast_PDB
85.18
30%
-91
- C2 -
4N93
6
TRPD_MYCTU
A:
[30-368]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
-
D
--
T
V
P
D
D
-
A
---
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
-
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
---
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
-----
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
----
A
A
A
V
R
A
V
L
G
G
A
R
G
P
V
R
D
---
A
V
V
L
-
N
A
A
G
A
I
V
A
H
A
G
L
S
S
-
A
E
--
W
L
P
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
17
PsiBlast_PDB
85.16
30%
-91
- C2 -
4M0R
4
TRPD_MYCTO
A:
[31-369]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
-
D
--
T
V
P
D
D
-
A
---
V
D
V
V
G
T
G
---
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
-
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
---
R
R
S
SV
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
-----
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
----
A
A
A
V
R
A
V
L
G
G
A
R
G
P
V
R
D
---
A
V
V
L
-
N
A
A
G
A
I
V
A
H
A
G
L
S
S
R
A
E
--
W
L
P
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
13
PsiBlast_PDB
85.09
30%
-91
- C2 -
4N5V
7
TRPD_MYCTU
A:
[30-368]
----
I
L
G
R
L
T
D
N
R
D
L
A
R
G
Q
A
A
W
A
M
D
Q
I
M
T
G
N
A
R
P
A
Q
I
A
A
F
A
V
A
M
T
M
K
A
P
T
A
D
E
V
G
E
L
A
G
V
M
L
S
H
A
H
P
L
P
A
-
D
--
T
V
P
D
D
-
A
---
V
D
V
V
G
T
G
G
D
G
V
N
T
V
N
L
S
T
M
A
A
I
V
V
A
A
A
G
V
P
V
V
K
H
G
N
R
A
A
S
S
L
-
S
G
G
A
D
T
L
E
A
L
G
V
R
I
D
L
G
P
D
L
V
A
R
S
L
A
E
V
G
I
G
F
C
F
A
P
R
F
H
P
S
Y
R
H
A
A
A
V
R
R
E
I
G
V
P
T
V
F
N
L
L
G
P
L
T
N
P
A
R
P
R
A
G
L
I
G
C
A
F
A
D
L
A
E
V
M
A
G
V
F
A
A
---
R
R
S
S
V
L
V
V
H
G
D
D
G
L
D
E
L
T
T
T
T
T
S
T
I
W
R
V
A
A
G
S
V
D
K
-----
L
T
F
D
P
A
G
F
G
F
A
R
A
Q
L
D
Q
L
A
G
G
D
A
Q
A
N
----
A
A
A
V
R
A
V
L
G
G
A
R
G
P
V
R
D
---
A
V
V
L
-
N
A
A
G
A
I
V
A
H
A
G
L
S
S
-
A
E
--
W
L
P
A
W
E
E
G
L
R
R
A
S
A
A
I
D
T
G
A
A
E
Q
L
L
A
R
W
V
R
F
G
R
Q
11
PsiBlast_PDB
81.32
35%
-93
- C2 -
2ELC
4
TRPD_THET8
A:
[29-324]
------------------------------
E
V
S
P
V
R
A
A
G
L
L
V
A
L
S
L
R
G
E
R
P
H
E
I
A
A
M
A
R
A
M
R
E
A
A
-
R
P
L
R
-
V
--
H
-
R
R
P
-
L
---
L
D
I
V
G
T
G
G
D
G
K
G
L
M
N
L
S
T
L
A
A
L
V
A
A
A
G
G
V
A
V
A
K
H
G
N
R
A
A
S
S
R
-
A
G
S
A
D
L
L
E
A
L
G
V
D
L
E
A
P
P
E
R
V
G
E
A
I
E
E
L
G
F
G
F
L
F
A
R
V
F
H
P
A
M
R
H
V
A
P
V
R
A
E
L
G
V
R
T
V
F
N
L
L
G
P
L
T
N
P
A
G
A
D
A
Y
V
L
G
V
F
S
P
E
W
L
A
P
M
A
E
A
L
E
R
L
G
A
-
R
G
--
L
V
V
H
G
-
E
G
A
D
E
L
V
L
G
E
---------
N
R
V
V
E
VG
K
G
A
Y
A
L
T
P
E
E
V
G
L
K
R
A
P
L
E
A
L
K
G
G
G
P
E
E
N
----
A
A
L
A
R
R
L
L
K
G
-
E
E
--
K
G
---
P
L
A
D
-
A
V
A
L
A
A
G
A
G
F
Y
A
A
G
K
T
P
--
S
L
---
K
E
G
V
A
L
A
R
E
V
L
A
S
G
E
A
Y
L
L
L
E
R
Y
V
A
F
L
R
A
34
PsiBlast_CBE
80.86
35%
-94
- C2 -
2ELC
2
TRPD_THET8
D:
[29-324]
------------------------------
E
V
S
P
V
R
A
A
G
L
L
V
A
L
S
L
R
G
E
R
P
H
E
I
A
A
M
A
R
A
M
R
E
A
A
-
R
P
L
R
-
V
--
H
-
R
R
P
-
L
---
L
D
I
V
G
T
G
G
D
G
K
G
L
M
N
L
S
T
L
A
A
L
V
A
A
A
G
G
V
A
V
A
K
H
G
N
R
A
A
S
S
R
-
A
G
S
A
D
L
L
E
A
L
G
V
D
L
E
A
P
P
E
R
V
G
E
A
I
E
E
L
G
F
G
F
L
F
A
R
V
F
H
P
A
M
R
H
V
A
P
V
R
A
E
L
G
V
R
T
V
F
N
L
L
G
P
L
T
N
P
A
G
A
D
A
Y
V
L
G
V
F
S
P
E
W
L
A
P
M
A
E
A
L
E
R
L
G
A
-
R
G
--
L
V
V
H
G
-
E
G
A
D
E
L
V
L
G
E
---------
N
R
V
V
E
VGKGA
Y
A
L
T
P
E
E
V
G
L
K
R
A
P
L
E
A
L
K
G
G
G
P
E
E
N
----
A
A
L
A
R
R
L
L
K
G
-
E
E
--
K
G
---
P
L
A
D
-
A
V
A
L
A
A
G
A
G
F
Y
A
A
G
K
T
P
--
S
L
---
K
E
G
V
A
L
A
R
E
V
L
A
S
G
E
A
Y
L
L
L
E
R
Y
V
A
F
L
R
A
35
PsiBlast_CBE
80.11
35%
-91
- C2 -
2ELC
3
TRPD_THET8
C:
[29-324]
------------------------------
E
V
S
P
V
R
A
A
G
L
L
V
A
L
S
L
R
G
E
R
P
H
E
I
A
A
M
A
R
A
M
R
E
A
A
-
R
P
L
R
-
V
--
H
-
R
R
P
-
L
---
L
D
I
V
G
T
G
G
D
G
K
G
L
M
N
L
S
T
L
A
A
L
V
A
A
A
G
G
V
A
V
A
K
H
G
N
R
A
A
S
S
R
-
A
G
S
A
D
L
L
E
A
L
G
V
D
L
E
A
P
P
E
R
V
G
E
A
I
E
E
L
G
F
G
F
L
F
A
R
V
F
H
P
A
M
R
H
V
A
P
V
R
A
E
L
G
V
R
T
V
F
N
L
L
G
P
L
T
N
P
A
G
A
D
A
Y
V
L
G
V
F
S
P
E
W
L
A
P
M
A
E
A
L
E
R
L
G
A
-
R
G
--
L
V
V
H
G
-
E
G
A
D
E
L
V
L
G
E
---------
N
R
V
V
E
VGKGA
Y
A
L
T
P
E
E
V
G
L
K
R
A
P
L
E
A
L
K
G
G
G
P
E
E
N
----
A
A
L
A
R
R
L
L
K
G
-
E
E
--
K
G
---
P
L
A
D
-
A
V
A
L
A
A
G
A
G
F
Y
A
A
G
K
T
P
--
S
L
---
K
E
G
V
A
L
A
R
E
V
L
A
S
G
E
A
Y
L
L
L
E
R
Y
V
A
F
L
R
A