@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_1260: (2015-12-22 )
MKISPSPRKLSKVSTSVSFLISFALYAIGFGYFLLREDAPEPLAQAGTTKVTMSLASINTNSNTKTNAESAKPKEEPKEKPKKEEPKKEEPKKETKPKPKPKPKPKPKPKPKPKPEPKPKPEPKVEEPKKEEPKEEPKKEEAKEEAKEKSVPKQVTTKDIVKEKDKQEESNKTSEGATSEAQAYNPGVSNEFLMKIQTAISSKNRYPKMAQIRGIEGEVLVSFTINADGSVTDIKVVKSNTTDILNHAALEAIKSAAHLFPKPDETVHLKIPIAYSLKED
Atome Classification :
(20 SA)
---------------------------------------------------------------------------------.........10........20.....------...30....----....40.....-...50........60........70........80........90...---.....100.......110.......120.......130.......140.......150........160.---------------......170......---------------.180.......190...-------....200..----------------------.....210-........-----.220.......--230..------.....240--..------.......250.......260...--.-----.--.-.270.-----......280--------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------------------------------------------------------------------MKISPS
P
R
K
L
S
K
V
S
T
S
V
S
F
L
I
S
F
A
L
Y
------
A
I
G
F
G
Y
F
L
L----REDAPE
P
L
A
QA-GT
T
K
V
T
M
S
L
A
S
INTNSNTKTNAESAKPKEEPKEKPKKEEPKKEEPKKE---TKPKPKPKPKPKPKPKPKPKPEPKPKPEPKVEEPKKEEPKEEP
K
K
E
E
A
K
E
E
A
K
E
KS-VPKQV
T
T
K
D
I
V
K
E
---------------
K
D
K
QEESNKTSEGAT---------------SEAQAYNPGV
S
N
E
F
L
M
K
-------
I
Q
T
A
ISSKN----------------------RYPK
M
A
---QIRGIE
G
E
-----
V
L
V
S
F
T
INADG--
S
V
T
D
I
------
K
V
VKSN----
T
T
------
D
I
L
N
H
A
A
L
E
A
I
K
S
A
A
HLFPKPD
E
--
T
-----
V
--
H
-
L
K
I
P
I
-----
A
Y
SLKED----------
2
PsiBlast_PDB
76.82
25%
-76
- C3 -
1XX3
-
TONB_ECOLI
A:
[162-228]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
Y
P
A
R
A
---
Q
A
L
R
I
E
G
Q
-----
V
K
V
K
F
D
V
T
P
D
G
--
R
V
D
N
V
------
Q
I
L
S
A
K
----
P
A
------
N
M
F
E
R
E
V
K
N
A
M
R
R
W
R
Y
E
P
G
K
P
G
S
--
G
-----
I
--
V
-
V
N
I
------------------------
3
PsiBlast_PDB
74.68
25%
-96
- C3 -
1U07
-
TONB_ECOLI
A:
[163-228]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
P
A
R
A
---
Q
A
L
R
I
E
G
Q
-----
V
K
V
K
F
D
V
T
P
D
G
--
R
V
D
N
V
------
Q
I
L
S
A
K
----
P
A
------
N
M
F
E
R
E
V
K
N
A
M
R
R
W
R
Y
E
P
G
K
P
G
S
--
G
-----
I
--
V
-
V
N
I
------------------------
13
HHSearch
73.96
27%
-83
- C3 -
2K9K
-
?
A:
[118-205]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
-------
A
M
P
L
Y
R
V
E
P
----------------------
V
Y
P
S
R
A
---
L
K
R
G
V
E
G
F
-----
V
T
L
S
F
T
I
D
T
T
G
--
K
A
V
D
I
------
N
V
V
D
A
N
----
P
K
------
R
M
F
E
R
E
A
M
Q
A
L
K
K
W
-
K
Y
Q
P
Q
I
V
D
GK
A
-----
I
EQ
P
G
Q
T
V
T
V
-----
E
F
K
I
A
------------
14
HHSearch
69.69
21%
-81
- C3 -
1U07
-
TONB_ECOLI
A:
[158-233]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
N
Q
P
----------------------
Q
Y
P
A
R
A
---
Q
A
L
R
I
E
G
Q
-----
V
K
V
K
F
D
V
T
P
D
G
--
R
V
D
N
V
------
Q
I
L
S
A
K
----
P
A
------
N
M
F
E
R
E
V
K
N
A
M
R
R
W
-
R
Y
E
P
G
K
P
G
--
S
--------
G
-
I
V
V
N
I
-----
L
F
K
I
N
------------
4
PsiBlast_PDB
69.36
25%
-86
- C3 -
2GSK
-
B:
[10-76]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
Y
P
A
R
A
---
Q
A
L
R
I
E
G
Q
-----
V
K
V
K
F
D
V
T
P
D
G
--
R
V
D
N
V
------
Q
I
L
S
A
K
----
P
A
------
N
M
F
E
R
E
V
K
N
A
M
R
R
W
R
Y
E
P
G
K
P
G
S
--
G
-----
I
--
V
-
V
N
I
L
F
-----
K
I
N
--------------
10
HHSearch
68.84
17%
-83
- C3 -
1LR0
1
A:
[23-120]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
S
E
V
T
G
S
L
D
D
L
-------
I
V
N
L
V
S
Q
Q
W
----------------------
R
R
P
P
S
A
------
R
N
G
M
S
-----
V
E
V
L
I
E
M
L
P
D
G
--
T
I
T
N
A
------
S
V
S
R
S
S
----
G
D
------
K
P
F
D
S
S
A
V
A
A
V
R
N
V
G
R
I
P
E
M
Q
Q
L
P-
R
A
T
F
D
S
L
--
Y
-
R
Q
R
R
I
-----
I
F
K
P
E
D
L
----------
1
PsiBlast_PDB
64.56
42%
-63
- C3 -
2K9K
-
?
A:
[129-177]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
P
S
R
A
---
L
K
R
G
V
E
G
F
-----
V
T
L
S
F
T
I
D
T
T
G
--
K
A
V
D
I
------
N
V
V
D
A
N
----
P
K
------
R
M
F
E
R
E
A
M
Q
A
L
K
---------------------------------------------------
9
HHSearch
64.43
18%
-76
- C3 -
2GRX
-
TONB_ECOLI
C:
[148-224]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
N
Q
P
----------------------
Q
Y
P
A
R
A
---
Q
A
L
R
I
E
G
Q
-----
V
K
V
K
F
D
V
T
P
D
G
--
R
V
D
N
V
------
Q
I
L
S
A
K
----
P
A
------
N
M
F
E
R
E
V
K
N
A
M
R
R
W
-
R
Y
E
P
G
K
P
G
--
S
--------
G
-
I
V
V
N
I
-----
L
F
K
I
N
G
-----------
25
Fugue
59.91
11%
68
* C5 *
1QLE
4
COX3_PARDE
C:
[1-273]
-------------------------------------------------------------------------AHVKNHDY
Q
I
L
P
P
S
I
W
P
F
F
G
A
I
G
A
F
V
M
L
T
G
A
V
A
W
------
M
K
G
I
T
F
F
G
L
----
P
V
E
G
P
---
W
M
F
-
L
I
G
L
V
G
V
L
Y
V
M
F
G
W
W
A
D
V
V
N
E
G
E
-
T
G
E
H
T
P
V
V
R
I
G
L
Q
Y
G
F
I
L
F
I
M
S
E
V
---
M
F
F
V
A
W
F
W
A
F
I
K
N
A
L
Y
P
M
G
P
D
S
P
I
K
D
G
V
W
P
P
E
G
I
V
T
F
D
P
W
H
L
P
L
I
N
T
L
I
L
L
L
S
G
V
A
-
V
--
T
W
A
H
H
A
F
V
L
----------------
E
G
D
R
K
T
T
I
N
G
L
I
V
A
V
---------------
I
L
G
V
C
F
T
G
L
Q
A
Y
E
Y
S
H
A
---------
A
F
G
L
-
A
D
----------------------
T
V
Y
A
G
A
---
F
Y
M
A
T
G
F
H
-----
G
A
H
V
I
I
G
T
I
F
L
--
F
V
C
L
I
------
R
L
L
K
G
Q
----
M
T
------
Q
-
K
Q
H
V
G
F
E
A
A
A
W
Y
W
H
F
V
D
V
V
W
L
--
F
-----
L
--
F
-
V
V
I
Y
I
-----
W
G
R
--------------
6
PsiBlast_PDB
58.44
24%
-52
- C3 -
1QXX
-
TONB_ECOLI
A:
[164-228]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
A
R
A
---
Q
A
L
R
I
E
G
Q
-----
V
K
V
K
F
D
V
T
P
D
G
--
R
V
D
N
V
------
Q
I
L
S
A
K
----
P
A
------
N
M
F
E
R
E
V
K
N
A
M
R
R
W
R
Y
E
P
G
K
P
G
S
--
G
-----
I
--
V
-
V
N
I
------------------------
21
Fugue
54.75
11%
55
* C4 *
3V39
5
?
A:
[1-402]
------------------------------------M
K
V
Y
L
N
S
M
C
H
M
A
ANSKTQ
Q
I
Q
G
D
DNKDDKFPLAS
I
S
K
V
V
T
T
L
W
A
V
D
R
L
G
P
D
Y
R
F
K
T
K
L
H
V
T
P
T
A
N
G
S
Y
D
I
H
------
I
E
G
S
R
D
P
L
F
G
R
N
M
S
Y
F
L
I
S
E
L
N
R
M
-
K
I
T
K
I
E
K
L
T
F
D
E
N
F
L
L
A
W
L
A
E
E
K
P
M
I
G
G
T
T
P
K
Y
D
T
V
E
Q
Q
A
S
I
V
R
A
T
L
T
S
SF
A
T
A
I
S
P
G
Y
Y
T
I
L
K
T
K
A
A
R
I
G
V
Q
M
S
N
R
P
K
I
D
V
R
T
I
S
F
V
-
K
K
A
E
F
Q
K
N
E
K
S
T
T
M
V
L
M
S
-
A
P
L
K
T
I
L
K
R
M
N
N
Q
SN
N
Y
I
A
D
N
L
Y
W
N
L
GG
T
E
A
F
N
A
Y
I
A
G
K
M
Q
A
D
TSDIEFHNGSGNNEG
S
V
A
K
P
V
Y
N
E
A
T
C
E
M
M
I
K
-------
V
L
Y
S
L
D
K
S
L
S
A
K
GYDLSDVMAVAAKDKASTV
G
S
Y
G
G
V
MAG
S
T
T
A
K
T
G
S
V
NK
A
K
T
L
M
G
S
V
S
T
K
N
G
--
E
I
Y
F
A
------
V
L
M
H
T
D
----
Y
D
KSRSDW
G
V
A
S
Q
Q
I
K
N
K
V
S
Q
L
I
N
Q
N
G
G
P
K
A
--
I
-----
K
--
Y
-
T
E
Q
L
P
L
PFDK
Y
S
Y
L
T
K
A
----------
19
Fugue
52.76
20%
-48
- C3 -
1IHR
2
TONB_ECOLI
A:
[2-74]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
A
---
Q
A
L
R
I
E
G
Q
-----
V
K
V
K
F
D
V
T
P
D
G
--
R
V
D
N
V
------
Q
I
L
S
A
K
----
P
A
------
N
M
F
E
R
E
V
K
N
A
M
R
R
W
R
Y
E
P
G
K
P
G
S
--
G
-----
I
--
V
-
V
N
I
L
F
-----
K
I
N
G
T
T
E
----------
26
Fugue
51.56
16%
79
- C5 -
1Q0V
-
VPS27_YEAST
A:
[249-329]
-------------------------------------------------------------------------------------------------------------------------------------------------------------
M
D
R
D
Y
S
T
P
E
D
E
E
E
L
I
R
K
A
I
E
L
S
L
K
E
S
R
N
S
---
A
S
S
E
P
I
V
P
V
V
E
S
K
N
E
V
K
R
Q
E
I
E
E
E
E
D
P
D
L
K
A
A
I
Q
E
S
L
R
E
A
E
E
A
K
L
R
S
E
R
Q
K
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
50.73
24%
-33
- C3 -
1IHR
2
TONB_ECOLI
A:
[2-65]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
R
A
---
Q
A
L
R
I
E
G
Q
-----
V
K
V
K
F
D
V
T
P
D
G
--
R
V
D
N
V
------
Q
I
L
S
A
K
----
P
A
------
N
M
F
E
R
E
V
K
N
A
M
R
R
W
R
Y
E
P
G
K
P
G
S
--
G
-----
I
--
V
-
V
N
I
L
F
-----
K
I
N
G
T
T
E
----------
28
Fugue
48.71
10%
36
- C2 -
3BMA
10
?
A:
[7-398]
MHHN
L
G
A
E
K
R
S
A
V
ATTIDSFKE
R
S
Q
K
V
R
A
L
S
DPN
V
R
F
V
P
F
F
G
S
SEWLRFDGAH
P
A
V
L
A
E
K
Y
NRSYRPY
L
L
G
Q
GGAA
S
L
N
Q
Y
F
G
M
Q
Q
M
L
P
Q
L
E
N
--
K
Q
V
V
Y
V
I
S
P
Q
W
F
SKNGYD
P
A
A
F
Q
Q
Y
F
N
----
G
D
Q
L
T
S
F
L
K
H
Q
S
G
D
Q
A
S
Q
Y
A
A
T
R
L
L
Q
Q
F
P
N
V
A
M
K
D
L
V
Q
K
L
A
S
K
E
E
L
S
T
A
D
N
E
M
I
E
L
L
A
R
F
---
N
E
R
Q
A
S
F
F
G
Q
F
S
V
R
G
Y
V
N
Y
D
K
H
V
A
K
Y
L
K
I
L
P
D
Q
F
S
Y
Q
A
I
E
D
V
V
K
A
D
A
E
K
N
T
S
N
N
E
M
G
M
E
N
Y
F
Y
N
E
Q
I
K
K
D
---------------
L
K
K
L
K
D
S
Q
K
S
F
T
Y
L
K
---------------
S
P
E
Y
N
D
L
Q
L
V
L
T
Q
F
S
K
S
K
V
N
P
I
F
I
I
P
P
V
N
K
K
W
M
----------------------
D
Y
A
G
L
R
---
E
D
M
Y
Q
Q
T
V
-----
Q
K
I
R
Y
Q
L
E
S
Q
G
FT
N
I
A
D
F
SKDGGE
P
F
F
M
K
D
----
T
I
------
H
L
G
W
L
G
W
L
A
F
D
K
A
V
D
P
F
L
S
N
P
T
P
--
A
-----
P
--
T
-
Y
H
L
N
E
-----
R
F
F
S
K
D
W
A
T
YDGDVKEF
27
Fugue
47.35
10%
26
- C1 -
1MV3
-
BIN1_HUMAN
A:
[270-482]
-------------------------------------------------------------------------------------------------------------------------------
D
G
S
P
A
A
T
P
E
I
-
R
V
N
H
-----------
E
P
E
P
A
G
G
A
T
P
G
A
T
L
P
K
S
P
S
Q
L
R
K
G
P
P
V
P
P
P
P
K
H
---
T
P
S
K
E
V
K
Q
E
Q
I
L
S
L
F
E
D
T
F
V
P
E
I
S
V
T
T
P
S
Q
P
A
E
A
S
E
V
A
G
G
T
Q
P
A
A
G
A
Q
E
P
G
E
T
A
A
S
-
E
A
A
S
S
S
L
P
A
V
V
V
E
---------------
T
F
P
A
T
V
N
G
T
V
E
G
G
S
G
---------------
A
G
R
L
D
L
P
P
G
F
M
F
K
V
Q
A
Q
-------
H
D
Y
T
A
T
D
T
D
----------------------
E
-----------------------
L
Q
L
K
A
G
-------
D
V
V
------
L
V
I
P
F
Q
----
N
P
------
E
E
Q
D
E
G
W
L
M
G
V
K
E
S
D
W
N
Q
H
K
K
L
E
--
K
-----
C
--
R
-
G
V
F
P
E
-----
N
F
T
E
R
V
P
----------
18
HHSearch
44.67
19%
-77
* C3 *
3F42
3
Y035_HELPY
A:
[39-77]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
S
V
S
F
N
G
L
G
--
E
L
V
D
L
------
Q
I
D
D
S
L
LE--
D
K
------
E
A
M
Q
I
Y
L
M
S
A
L
N
D
G
Y
K
A
V
E
E
N
R
K
--
N
-----
L
--
A
-
F
N
M
L
G
----------------------
16
HHSearch
43.28
16%
-82
- C3 -
1YBX
2
Y2143_CLOTH
A:
[77-118]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
T
V
V
A
T
G
R
K
--
D
I
K
E
I
------
T
I
K
P
E
V
VDPD
D
V
------
E
M
L
Q
D
L
I
L
A
A
V
N
E
A
L
------------------------------------------------
24
Fugue
38.13
27%
129
- C4 -
2K6I
-
Y223_METJA
A:
[1-47]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
G
V
S
V
M
E
A
I
K
E
V
K
L
A
E
E
Q
A
V
K
E
I
E
E
A
K
N
R
A
E
Q
I
K
A
E
A
I
E
E
A
K
K
L
I
-
A
C
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
37.95
26%
2
- C3 -
1J8B
-
Y442_HAEIN
A:
[41-81]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
V
K
I
T
I
N
G
A
H
--
N
C
R
R
I
------
D
I
D
P
S
L
M
E
D-
D
K
------
E
M
L
E
D
L
I
A
A
A
F
N
D
A
V
R
R
A
E
E
L
Q
K
--
E
-----
K
--
M
-
A
S
V
T
A
-----
G
----------------