@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_1358: (2015-12-23 )
MNATNNQVLIEVKDLHSAFGSTIIHRGVSFSVHKGEVMAILGGSGSGKSTLLRCMILLNRPTKGEVLLFGEDIWKLKEAEQQKIFNRCGICFQFGALYSSLTVLENVGVMLEQYGAYSKKIVEEISKMWIERVGLPPRAYHLYPYELSGGMTKRVGIARAMATNPEILFLDEPTSGLDPYSAGKFDELIMTLKESLQLTVVMITHDLDSVHDCVDRFIMLKDGLLEFNGDLKDFIKKAQTQGLDEGNLFNSTRGEKFWKGM
Atome Classification :
(20 SA)
.........10........--20---.----....--....30........40........50........60........70..-------.....----------.80.-...---....90........100.......110-........120.......130.......140.......150.......160.......170.......180.......190.....--..200.......210.......220.......230...---....240...----....250--.......260----------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MNATN
N
Q
V
L
I
E
V
K
D
L
H
S
A
F
--
G
----
S
----
T
I
I
H--RG
V
S
F
S
VHK
G
E
V
M
A
I
LGGSGS
G
K
S
T
L
L
R
C
M
I
L
LNRPTKG
E
V
L
L
FG
E
D
I
-------
W
K
L
K
E
----------
A
E
Q
Q
-
K
I
F
---
N
RC
G
I
C
F
Q
F
G
A
L
Y
S
S
L
T
V
L
E
N
V
G
V
M
L
--
E
QYG
A
Y
S
K
K
I
V
E
E
I
S
K
M
W
I
E
RVGLPPR
A
Y
H
L
Y
P
Y
ELSGGM
T
K
RVG
I
A
R
AMATNP
E
I
L
F
L
DEPTSGLDPYSAG
K
F
D
E
L
I
M
T
L
K
ESL
Q
--
L
T
V
V
M
I
TH
D
L
D
S
V
H
D
C
V
D
R
F
I
M
L
KD
G
L
LEFNG
D
L
K
D
F
I
---
K
K
A
Q
TQGLDE----GNLFNST--RG
E
K
FWKGM-----------------------------------------------------------------------------------------
16
PsiBlast_PDB
95.49
35%
-119
- C1 -
1B0U
4
HISP_SALTY
A:
[7-251]
---------
L
H
V
I
D
L
H
K
R
Y
--
G
----
G
----
H
E
V
L
--
K
G
V
S
L
Q
A
R
A
G
D
V
I
S
I
I
G
S
S
G
S
G
K
S
T
F
L
R
C
I
N
F
L
E
K
P
S
E
G
A
I
I
V
N
G
Q
N
I
N
L
V
R
D
KD
G
Q
L
K
V
----------
A
D
K
N
-
Q
L
R
L
L
R
T
R
L
T
M
V
F
Q
H
F
N
L
W
S
H
M
T
V
L
E
N
V
M
E
A
P
--
I
Q
V
L
G
L
S
K
H
D
A
R
E
R
A
L
K
Y
L
A
K
V
G
I
D
E
R
A
Q
G
K
Y
P
V
H
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
E
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
E
L
V
G
E
V
L
R
I
M
Q
Q
L
A
E
E
G
K
---
T
M
V
V
V
T
H
E
M
G
F
A
R
H
V
S
S
H
V
I
F
L
H
Q
G
K
I
E
E
E
G
D
P
E
Q
V
F
---
G
N
P
Q
S
P
R
L
Q
Q
----
F
L
K
G
S
L
K
--
K
L
E
H
----------------------------------------------------------------------------------------------
96
HHSearch
95.07
34%
-123
- C1 -
1B0U
4
HISP_SALTY
A:
[5-256]
-------
N
K
L
H
V
I
D
L
H
K
R
Y
--
G
----
G
----
H
E
V
L
--
K
G
V
S
L
Q
A
R
A
G
D
V
I
S
I
I
G
S
S
G
S
G
K
S
T
F
L
R
C
I
N
F
L
E
K
P
S
E
G
A
I
I
V
N
G
Q
N
I
-------
N
L
V
R
D
KDGQLKVAD
K
N
Q
L
R
-
L
L
R
---
T
R
L
T
M
V
F
Q
H
F
N
L
W
S
H
M
T
V
L
E
N
V
M
E
A
P
--
I
Q
V
L
G
L
S
K
H
D
A
R
E
R
A
L
K
Y
L
A
K
V
G
I
D
E
R
A
Q
G
K
Y
P
V
H
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
E
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
E
L
V
G
E
V
L
R
I
M
Q
Q
L
A
E
E
-
G
--
K
T
M
V
V
V
T
H
E
M
G
F
A
R
H
V
S
S
H
V
I
F
L
H
Q
G
K
I
E
E
E
G
D
P
E
Q
V
F
---
G
N
P
Q
S
P
R
--
L
----
Q
Q
F
L
K
G
S
--
L
K
K
L
E
H
--------------------------------------------------------------------------------------------
48
PsiBlast_CBE
94.15
35%
-138
- C1 -
3TIF
7
Y796_METJA
B:
[1-232]
--------
M
V
K
L
K
N
V
T
K
T
Y
KM
G
----
E
----
E
I
I
Y
AL
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
-------
N
D
L
D
D
----------
D
E
L
T
-
K
I
R
R--
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
P
L
IF
K
Y
R
G
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
E
E
R
F
A
N
H
K
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
--
K
T
V
V
V
V
T
H
D
I
N
-
V
A
R
F
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
E
E
K
L
R
G
F
-----------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
93.93
37%
-135
- C1 -
4YMU
2
?
A:
[1-230]
--------
M
I
F
V
N
D
V
Y
K
N
F
--
G
----
S
----
L
E
V
L
--
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
-------
N
N
G
K
-----------
V
N
I
N
-
K
V
R
---
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
--
V
K
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
K
K
D
Q
-
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
---
K
E
V
L
N
V
M
K
Q
L
A
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
---
Y
R
A
K
N
E
R
T
R
E
----
F
L
S
K
I
L
-----------------------------------------------------------------------------------------------------
45
PsiBlast_CBE
93.83
36%
-136
- C1 -
1L2T
4
Y796_METJA
B:
[1-232]
--------
M
I
K
L
K
N
V
T
K
T
Y
KM
G
----
E
----
E
I
I
Y
AL
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
-------
N
D
L
D
D
----------
D
E
L
T
-
K
I
R
R--
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
P
L
IF
K
Y
R
G
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
E
E
R
F
A
N
H
K
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
--
K
T
V
V
V
V
T
H
D
I
N
-
V
A
R
F
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
E
E
K
L
R
G
F
-----------------------------------------------------------------------------------------------------------------------------
46
PsiBlast_CBE
93.62
36%
-134
- C1 -
1L2T
4
Y796_METJA
A:
[1-230]
--------
M
I
K
L
K
N
V
T
K
T
Y
K
M
G
----
E
----
E
I
I
Y
AL
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
-------
N
D
L
D
D
----------
D
E
L
T
-
K
I
R
R
--
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
P
L
IF
K
Y
R
G
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
E
E
R
F
A
N
H
K
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
--
K
T
V
V
V
V
T
H
D
I
N
-
V
A
R
F
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
E
E
K
L
R
-------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
92.79
37%
-134
- C1 -
4YMU
2
?
J:
[1-230]
--------
M
I
F
V
N
D
V
Y
K
N
F
--
G
----
S
----
L
E
V
L
--
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
-------
N
N
G
K
-----------
V
N
I
N
-
K
V
R
---
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
--
V
K
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
K
K
D
Q
-
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
---
K
E
V
L
N
V
M
K
Q
L
A
N
EG
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
---
Y
R
A
K
N
E
R
T
R
E
----
F
L
S
K
I
L
-----------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
92.67
37%
-130
- C1 -
4YMV
1
?
J:
[1-230]
--------
M
I
F
V
N
D
V
Y
K
N
F
--
G
----
S
----
L
E
V
L
--
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
-------
N
N
G
K
-----------
V
N
I
N
-
K
V
R
---
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
--
V
K
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
K
K
D
Q
-
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
---
K
E
V
L
N
V
M
K
Q
L
A
N
EG
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
---
Y
R
A
K
N
E
R
T
R
E
----
F
L
S
K
I
L
-----------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
92.64
37%
-129
- C1 -
4YMV
1
?
A:
[1-230]
--------
M
I
F
V
N
D
V
Y
K
N
F
--
G
----
S
----
L
E
V
L
--
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
-------
N
N
G
K
-----------
V
N
I
N
-
K
V
R
---
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
--
V
K
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
K
K
D
Q
-
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
---
K
E
V
L
N
V
M
K
Q
L
A
N
E
G
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
---
Y
R
A
K
N
E
R
T
R
E
----
F
L
S
K
I
L
-----------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
92.25
37%
-133
- C1 -
4YMW
-
?
J:
[1-230]
--------
M
I
F
V
N
D
V
Y
K
N
F
--
G
----
S
----
L
E
V
L
--
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
-------
N
N
G
K
-----------
V
N
I
N
-
K
V
R
---
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
--
V
K
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
K
K
D
Q
-
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
---
K
E
V
L
N
V
M
K
Q
L
A
N
EG
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
---
Y
R
A
K
N
E
R
T
R
E
----
F
L
S
K
I
L
-----------------------------------------------------------------------------------------------------
88
HHSearch
92.12
35%
-139
* C1 *
3TUI
1
METN_ECOLI
C:
[23-256]
-------
H
M
I
K
L
S
N
I
T
K
V
F
--
H
----
Q
GTRT
I
Q
A
L
--
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
-------
T
T
L
S
E
----------
S
E
L
T
-
K
A
R
---
R
Q
I
G
M
I
F
Q
H
F
N
L
L
S
S
R
T
V
F
G
N
V
A
L
P
L
--
E
L
D
N
T
-
P
K
D
E
V
K
R
R
V
T
E
L
L
S
L
V
G
L
G
D
-
K
H
D
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
--
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
---
S
H
P
K
T
P
L
A
Q
K
----
F
I
Q
S
T
L
H
--
L
D
I
P
E
D
Y
Q
E
-----------------------------------------------------------------------------------------
1
PsiBlast_PDB
91.91
37%
-133
- C1 -
4YMS
-
?
J:
[1-230]
--------
M
I
F
V
N
D
V
Y
K
N
F
--
G
----
S
----
L
E
V
L
--
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
-------
N
N
G
K
-----------
V
N
I
N
-
K
V
R
---
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
--
V
K
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
K
K
D
Q
-
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
---
K
E
V
L
N
V
M
K
Q
L
A
N
EG
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
---
Y
R
A
K
N
E
R
T
R
E
----
F
L
S
K
I
L
-----------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
91.10
37%
-133
- C1 -
4YMT
-
?
J:
[1-230]
--------
M
I
F
V
N
D
V
Y
K
N
F
--
G
----
S
----
L
E
V
L
--
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
V
K
I
-------
N
N
G
K
-----------
V
N
I
N
-
K
V
R
---
Q
K
V
G
M
V
F
Q
H
F
N
L
F
P
H
L
T
A
I
E
N
I
T
L
A
P
--
V
K
V
K
K
M
N
K
K
E
A
E
E
L
A
V
D
L
L
A
K
V
G
L
L
D
K
K
D
Q
-
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
---
K
E
V
L
N
V
M
K
Q
L
A
N
EG
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
---
Y
R
A
K
N
E
R
T
R
E
----
F
L
S
K
I
L
-----------------------------------------------------------------------------------------------------
49
PsiBlast_CBE
91.07
35%
-133
- C1 -
3TIF
7
Y796_METJA
A:
[1-230]
--------
M
V
K
L
K
N
V
T
K
T
Y
K
M
G
----
E
----
E
I
I
Y
AL
K
N
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
I
K
T
-------
N
D
L
D
D
----------
D
E
L
T
-
K
I
R
R
--
D
K
I
G
F
V
F
Q
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
E
L
P
L
IF
K
Y
R
G
A
M
S
G
E
E
R
R
K
R
A
L
E
C
L
K
M
A
E
L
E
E
R
F
A
N
H
K
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
E
E
D
G
--
K
T
V
V
V
V
T
H
D
I
N
-
V
A
R
F
G
E
R
I
I
Y
L
K
D
G
E
V
E
R
E
E
K
L
R
-------------------------------------------------------------------------------------------------------------------------------
76
Fugue
90.51
32%
-122
- C1 -
3TUZ
3
METN_ECOLI
H:
[23-362]
-------
H
M
I
K
L
S
N
I
T
K
V
F
--
H
QGTR
T
----
I
Q
A
L
--
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
Q
E
L
-------
T
T
L
S
E
----------
S
E
L
T
-
K
A
R
---
R
Q
I
G
M
I
F
Q
H
F
N
L
L
S
S
R
T
V
F
G
N
V
A
L
P
L
--
E
L
D
N
T
P
K
D
E
V
K
R
R
V
T
E
L
-
L
S
L
V
G
L
G
D
K
H
D
S
-
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
--
L
T
I
L
L
I
T
H
E
M
D
V
V
K
R
I
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
F
SHP
K
T
P
L
A
Q
K
F
I
Q
----
S
T
L
H
L
D
I
--
P
E
D
Y
Q
E
R
L
Q
AEPFTDCVPMLRLEFTGQSVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHHVKVEV--------
106
HHSearch
88.14
36%
-130
- C1 -
2PCJ
-
LOLD_AQUAE
A:
[2-223]
------
A
E
I
L
R
A
E
N
I
K
K
V
I
--
R
----
G
----
Y
E
I
L
--
K
G
I
S
L
S
V
K
K
G
E
F
V
S
I
I
G
A
S
G
S
G
K
S
T
L
L
Y
I
L
G
L
L
D
A
P
T
E
G
K
V
F
L
E
G
K
E
V
-------
D
Y
T
N
E
----------
K
E
L
S
L
L
R
N
---
R
K
L
G
F
V
F
Q
F
H
Y
L
I
P
E
L
T
A
L
E
N
V
I
V
P
M
--
L
K
M
G
K
-
P
K
K
E
A
K
E
R
G
E
Y
L
L
S
E
L
G
L
G
D
-
K
L
S
R
K
P
Y
E
L
S
G
G
E
Q
Q
R
V
A
I
A
R
A
L
A
N
E
P
I
L
L
F
A
D
E
P
T
G
N
L
D
S
A
N
T
K
R
V
M
D
I
F
L
K
I
N
E
-
G
G
--
T
S
I
V
M
V
T
H
E
R
E
L
-
A
E
L
T
H
R
T
L
E
M
K
D
G
K
V
V
G
E
I
T
R
V
-------------------------------------------------------------------------------------------------------------------------------
81
Fugue
86.77
30%
-109
- C1 -
1Z47
1
?
A:
[11-355]
-----
G
S
M
T
I
E
F
V
G
V
E
K
I
Y
P-
G
----
G
----
A
R
S
V
--
R
G
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
G
K
R
V
-------
T
D
L
P
P
----------
Q
K
R
N
---------
V
G
L
V
F
Q
N
Y
A
L
F
Q
H
M
T
V
Y
D
N
V
S
F
G
L
--
R
E
K
R
V
P
K
D
E
M
D
A
R
V
R
E
L
-
L
R
F
M
R
L
E
S
Y
A
N
R
-
F
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
Q
I
R
R
E
L
R
T
F
V
R
Q
V
H
D
E
M
G
--
V
T
S
V
F
V
T
H
D
Q
E
E
A
L
E
V
A
D
R
V
L
V
L
H
E
G
N
V
E
Q
F
G
T
P
E
E
V
Y
---
E
K
P
G
T
L
F
V
A
S
F
IGE
S
N
V
W
T
R
A
V
Q
N
G
R
I
E
V
A
G
A
A
L
P
V
DPAVSEG
S
E
V
A
V
V
V
R
PKD
V
E
L
Q
P
A
S
EREAHAQVV
R
S
A
F
KGS
Y
S
A
C
W
I
R
T
KD
G
E
V
W
E
V
H
V
P
SADRHRWSPG
A
W
V
H
M
N
V
T
R
W
F
I
F
P
R
36
PsiBlast_CBE
86.14
33%
-128
- C1 -
2OLK
2
?
B:
[24-253]
--------
M
I
D
V
H
Q
L
K
K
S
F
--
G
----
S
----
L
E
V
L
--
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
--------
K
A
K
D
----------
T
N
L
N
-
K
V
R
---
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
--
M
K
V
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
A
-
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
--
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
---
D
R
P
Q
H
E
R
T
K
A
----
F
L
S
K
V
F
-----------------------------------------------------------------------------------------------------
34
PsiBlast_CBE
85.26
33%
-125
- C1 -
2OLK
1
?
D:
[24-253]
--------
M
I
D
V
H
Q
L
K
K
S
F
--
G
----
S
----
L
E
V
L
--
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
--------
K
A
K
D
----------
T
N
L
N
-
K
V
R
---
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
--
M
K
V
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
A
-
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
--
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
---
D
R
P
Q
H
E
R
T
K
A
----
F
L
S
K
V
F
-----------------------------------------------------------------------------------------------------
33
PsiBlast_CBE
84.45
33%
-123
- C1 -
2OUK
2
?
B:
[24-253]
--------
M
I
D
V
H
Q
L
K
K
S
F
--
G
----
S
----
L
E
V
L
--
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
I
N
L
--------
K
A
K
D
----------
T
N
L
N
-
K
V
R
---
E
E
V
G
M
V
F
Q
R
F
N
L
F
P
H
M
T
V
L
N
N
I
T
L
A
P
--
M
K
V
R
K
W
P
R
E
K
A
E
A
K
A
M
E
L
L
D
K
V
G
L
K
D
K
A
-
H
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
--
M
T
M
V
V
V
T
H
E
M
G
F
A
R
E
V
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
---
D
R
P
Q
H
E
R
T
K
A
----
F
L
S
K
V
F
-----------------------------------------------------------------------------------------------------