@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_1417: (2015-12-23 )
MDTNNNIEKEILALVKQNPKVSLIEYENYLSQLKYNPNASKSDIAFFYAPNKFLCTTITAKYGALLKEILSQNKVGMHLAHSVDVRIEVAPKIQVNAQSNINYKATKTSVKDSYTFENFVVGSCNNTVYEIAKKVAQSDTPPYNPVLFYGGTGLGKTHILNAIGNHALEKHKKVVLVTSEDFLTDFLKHLDNKNMDSFKKKYRHCDFFLLDDAQFLQGKPKLEEEFFHTFNELHANSKQIVLISDRSPKNIAGLEDRLKSRFEWGITAKVMPPDLETKLSIVKQKCQLNKITLPEEVMEYIAQHISDNIRQMEGAIIKISVNANLMNATIDLNLAKTVLEDLQKDHAEGSSLENILLAVAQSLNLKSSEIKVSSRQKNVALARKLVVYFARLYTPNPTLSLAQFLDLKDHSSISKMYSSVKKMLEEEKSPFILSLREEIKNRLNELNDKKTAFNSSE
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160......--.170.--..---......180.--......190.......-200--.-.-.-.....210.......220.......230.......240.......250.--......260.......270.......280.......290.......300.......310.......320.......330.......340.-......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MDTN
N
N
I
E
K
E
I
L
A
L
V
KQNP
K
V
S
L
I
E
Y
E
N
Y
L
S
Q
LKYNPNASKS
D
I
A
F
F
YAPN
K
F
L
C
T
T
I
T
A
K
Y
G
A
L
L
K
E
I
L
SQNKV
G
M
H
L
A
H
S
V
D
V
R
I
E
VA
P
K
I
Q
V
N
AQSN
I
N
Y
K
ATKTSVKDSYTF
E
N
F
V
VGSCN
N
T
V
Y
E
I
A
K
K
V
AQSDTPPYN
P
V
L
F
YGGTGL
G
K
T
H
I
L
N
A
I
G
N
H
A
L
--
E
K--H--
K
K
---
V
V
L
V
T
S
E
D
F
L
--
T
D
F
L
K
H
LDNK
N
M
D
S
F
K
-
K
K
---Y-R-H-C
D
F
F
L
LD
D
A
Q
F
LQGKPK
L
E
E
E
F
F
H
T
F
N
E
LHANS
K
Q
I
V
L
I
SDRSPKN
I
A
G
--
L
E
D
R
L
K
S
R
F
EWG
I
T
A
KVMPP
D
L
E
T
K
L
S
I
V
K
Q
K
CQLNKIT
L
P
E
E
V
M
E
Y
I
A
Q
H
I
S
D
N
I
R
Q
MEG
A
I
I
K
I
S
V
NA
N
L
M
N
A
T
I
D
L
N
L
A
K
T
V
L
E
D
L
Q
-
K
D
HAEG
S
S
L
E
N
I
L
L
A
V
A
Q
SLNLKSS
E
I
K
VSSRQ
K
N
V
A
L
A
R
K
L
V
V
Y
F
A
R
LYTPNP
T
L
S
L
A
Q
F
LDLKDH
S
S
I
S
K
M
Y
S
S
V
K
K
M
L
E
EEKSP
F
I
L
S
L
R
E
E
I
K
N
R
L
N
ELNDKKTAFNSSE
42
HHSearch
96.46
33%
-101
- C2 -
1L8Q
2
DNAA_AQUAE
A:
[2-321]
-----------------------------------------------------------------------------------------------------------
D
F
L
N
P
K
Y
T
L
E
N
F
I
V
G
E
G
N
R
L
A
Y
E
V
V
K
E
A
L
E
N
L
G
S
L
Y
N
P
I
F
I
Y
G
S
V
G
T
G
K
T
H
L
L
Q
A
A
G
N
E
A
K
--
K
R
--
G
--
Y
R
---
V
I
Y
S
S
A
D
D
F
A
--
Q
A
M
V
E
H
L
K
K
G
T
I
N
E
F
R
-
N
M
---
Y
-
K
-
S
-
V
D
L
L
L
L
D
D
V
Q
F
L
S
G
K
E
R
T
Q
I
E
F
F
H
I
F
N
T
L
Y
L
L
E
K
Q
I
I
L
A
S
D
R
H
P
Q
K
L
D
G
--
V
S
D
R
L
V
S
R
F
E
G
G
I
L
V
E
I
E
L
-
D
N
K
T
R
F
K
I
I
K
E
K
L
K
E
F
N
L
E
L
R
K
E
V
I
D
Y
L
L
E
N
-
T
K
N
V
R
E
I
E
G
K
I
K
L
I
K
L
K
G
F
E
G
-
L
E
R
-
K
E
-------------
R
K
E
R
D
K
L
M
Q
I
V
E
F
V
A
N
Y
Y
A
V
K
V
E
D
I
L
S
D
K
R
N
K
R
T
S
E
A
R
K
I
A
M
Y
L
C
R
K
V
C
S
A
S
L
I
E
I
A
R
A
F
K
R
K
D
H
T
T
V
I
H
A
I
R
S
V
E
E
E
K
K
--
R
--
K
F
K
H
L
V
G
F
L
E
K
Q
A
F
D
K
I
C
---------
6
PsiBlast_PDB
92.42
34%
-98
- C2 -
1L8Q
2
DNAA_AQUAE
A:
[8-302]
-----------------------------------------------------------------------------------------------------------------
Y
T
L
E
N
F
I
V
G
E
G
N
R
L
A
Y
E
V
V
K
E
A
L
E
N
L
G
S
L
Y
N
P
I
F
I
Y
G
S
V
G
T
G
K
T
H
L
L
Q
A
A
G
N
E
A
K
--
K
R
--
G
--
Y
R
---
V
I
Y
S
S
A
D
D
F
A
--
Q
A
M
V
E
H
L
K
K
G
T
I
N
E
F
R
-
N
M
---
Y
-
K
-
S
-
V
D
L
L
L
L
D
D
V
Q
F
L
S
G
K
E
R
T
Q
I
E
F
F
H
I
F
N
T
L
Y
L
L
E
K
Q
I
I
L
A
S
D
R
H
P
Q
K
L
D
G
--
V
S
D
R
L
V
S
R
F
E
G
G
I
L
V
E
I
-
E
L
D
N
K
T
R
F
K
I
I
K
E
K
L
K
E
F
N
L
E
L
R
K
E
V
I
D
Y
L
L
E
N
-
T
K
N
V
R
E
I
E
G
K
I
K
L
I
K
L
K
G
---------------
F
E
G
L
E
R
K
E
R
K
E
R
D
K
L
M
Q
I
V
E
F
V
A
N
Y
Y
A
V
K
V
E
D
I
L
S
D
K
R
N
K
R
T
S
E
A
R
K
I
A
M
Y
L
C
R
K
V
C
S
A
S
L
I
E
I
A
R
A
F
K
R
K
D
H
T
T
V
I
H
A
I
R
S
V
----
E
E
E
K
K
R
K
F
K
H
L
V
G
F
L
E
K
Q
A
F
D
K
I
C
---------
26
PsiBlast_CBE
91.63
34%
-93
- C2 -
3R8F
3
DNAA_AQUAE
D:
[8-302]
-----------------------------------------------------------------------------------------------------------------
Y
T
L
E
N
F
I
V
G
E
G
N
R
L
A
Y
E
V
V
K
E
A
L
E
N
L
G
S
L
Y
N
P
I
F
I
Y
G
S
V
G
T
G
K
T
H
L
L
Q
A
A
G
N
E
A
K
--
K
R
--
G
--
Y
R
---
V
I
Y
S
S
A
D
D
F
A
--
Q
A
M
V
E
H
L
K
K
G
T
I
N
E
F
R
-
N
M
---
Y
-
K
-
S
-
V
D
L
L
L
L
D
D
V
Q
F
L
S
G
K
E
R
T
Q
I
E
F
F
H
I
F
N
T
L
Y
L
L
E
K
Q
I
I
L
A
S
D
R
H
P
Q
K
L
D
G
--
V
S
D
R
L
V
S
R
F
E
G
G
I
L
V
E
I
-
E
L
D
N
K
T
R
F
K
I
I
K
E
K
L
K
E
F
N
L
E
L
R
K
E
V
I
D
Y
L
L
E
N
-
T
K
N
V
R
E
I
E
G
K
I
K
L
I
K
L
K
G
---------------
F
E
G
L
E
R
K
E
R
K
E
R
D
K
L
M
Q
I
V
E
F
V
A
N
Y
Y
A
V
K
V
E
D
I
L
S
D
K
-
N
K
R
T
S
E
A
R
K
I
A
M
Y
L
C
R
K
V
C
S
A
S
L
I
E
I
A
R
A
F
K
R
K
D
H
T
T
V
I
H
A
I
R
S
V
----
E
E
E
K
R
K
F
K
H
L
V
G
F
L
E
K
Q
A
F
D
K
I
C
----------
27
PsiBlast_CBE
90.98
34%
-92
- C2 -
3R8F
4
DNAA_AQUAE
C:
[8-302]
-----------------------------------------------------------------------------------------------------------------
Y
T
L
E
N
F
I
V
G
E
G
N
R
L
A
Y
E
V
V
K
E
A
L
E
N
L
G
S
L
Y
N
P
I
F
I
Y
G
S
V
G
T
G
K
T
H
L
L
Q
A
A
G
N
E
A
K
--
K
R
--
G
--
Y
R
---
V
I
Y
S
S
A
D
D
F
A
--
Q
A
M
V
E
H
L
K
K
G
T
I
N
E
F
R
-
N
M
---
Y
-
K
-
S
-
V
D
L
L
L
L
D
D
V
Q
F
L
S
G
K
E
R
T
Q
I
E
F
F
H
I
F
N
T
L
Y
L
L
E
K
Q
I
I
L
A
S
D
R
H
P
Q
K
L
D
G
--
V
S
D
R
L
V
S
R
F
E
G
G
I
L
V
E
I
-
E
L
D
N
K
T
R
F
K
I
I
K
E
K
L
K
E
F
N
L
E
L
R
K
E
V
I
D
Y
L
L
E
N
-
T
K
N
V
R
E
I
E
G
K
I
K
L
I
K
L
K
G
---------------
F
E
G
L
E
R
K
E
R
K
E
R
D
K
L
M
Q
I
V
E
F
V
A
N
Y
Y
A
V
K
V
E
D
I
L
S
D
K
-
N
K
R
T
S
E
A
R
K
I
A
M
Y
L
C
R
K
V
C
S
A
S
L
I
E
I
A
R
A
F
K
R
K
D
H
T
T
V
I
H
A
I
R
S
V
----
E
E
E
K
R
K
F
K
H
L
V
G
F
L
E
K
Q
A
F
D
K
I
C
----------
25
PsiBlast_CBE
90.96
34%
-88
- C2 -
2HCB
3
DNAA_AQUAE
B:
[7-301]
-----------------------------------------------------------------------------------------------------------------
Y
T
L
E
N
F
I
V
G
E
G
N
R
L
A
Y
E
V
V
K
E
A
L
E
N
L
G
S
L
Y
N
P
I
F
I
Y
G
S
V
G
T
G
K
T
H
L
L
Q
A
A
G
N
E
A
K
--
K
R
--
G
--
Y
R
---
V
I
Y
S
S
A
D
D
F
A
--
Q
A
M
V
E
H
L
K
K
G
T
I
N
E
F
R
-
N
M
---
Y
-
K
-
S
-
V
D
L
L
L
L
D
D
V
Q
F
L
S
G
K
E
R
T
Q
I
E
F
F
H
I
F
N
T
L
Y
L
L
E
K
Q
I
I
L
A
S
D
R
H
P
Q
K
L
D
G
--
V
S
D
R
L
V
S
R
F
E
G
G
I
L
V
E
I
-
E
L
D
N
K
T
R
F
K
I
I
K
E
K
L
K
E
F
N
L
E
L
R
K
E
V
I
D
Y
L
L
E
N
-
T
K
N
V
R
E
I
E
G
K
I
K
L
I
K
L
K
G
---------------
F
E
G
L
E
R
K
E
R
K
E
R
D
K
L
M
Q
I
V
E
F
V
A
N
Y
Y
A
V
K
V
E
D
I
L
S
D
K
-
N
K
R
T
S
E
A
R
K
I
A
M
Y
L
C
R
K
V
C
S
A
S
L
I
E
I
A
R
A
F
K
--
D
H
T
T
V
I
H
A
I
R
S
V
----
E
E
E
K
K
R
K
F
K
H
L
V
G
F
L
E
K
Q
A
F
D
K
I
C
---------
28
PsiBlast_CBE
90.94
34%
-92
- C2 -
3R8F
4
DNAA_AQUAE
B:
[8-302]
-----------------------------------------------------------------------------------------------------------------
Y
T
L
E
N
F
I
V
G
E
G
N
R
L
A
Y
E
V
V
K
E
A
L
E
N
L
G
S
L
Y
N
P
I
F
I
Y
G
S
V
G
T
G
K
T
H
L
L
Q
A
A
G
N
E
A
K
--
K
R
--
G
--
Y
R
---
V
I
Y
S
S
A
D
D
F
A
--
Q
A
M
V
E
H
L
K
K
G
T
I
N
E
F
R
-
N
M
---
Y
-
K
-
S
-
V
D
L
L
L
L
D
D
V
Q
F
L
S
G
K
E
R
T
Q
I
E
F
F
H
I
F
N
T
L
Y
L
L
E
K
Q
I
I
L
A
S
D
R
H
P
Q
K
L
D
G
--
V
S
D
R
L
V
S
R
F
E
G
G
I
L
V
E
I
-
E
L
D
N
K
T
R
F
K
I
I
K
E
K
L
K
E
F
N
L
E
L
R
K
E
V
I
D
Y
L
L
E
N
-
T
K
N
V
R
E
I
E
G
K
I
K
L
I
K
L
K
G
---------------
F
E
G
L
E
R
K
E
R
K
E
R
D
K
L
M
Q
I
V
E
F
V
A
N
Y
Y
A
V
K
V
E
D
I
L
S
D
K
-
N
K
R
T
S
E
A
R
K
I
A
M
Y
L
C
R
K
V
C
S
A
S
L
I
E
I
A
R
A
F
K
R
K
D
H
T
T
V
I
H
A
I
R
S
V
----
E
E
E
K
R
K
F
K
H
L
V
G
F
L
E
K
Q
A
F
D
K
I
C
----------
5
PsiBlast_PDB
90.88
34%
-92
- C2 -
3R8F
4
DNAA_AQUAE
A:
[8-302]
-----------------------------------------------------------------------------------------------------------------
Y
T
L
E
N
F
I
V
G
E
G
N
R
L
A
Y
E
V
V
K
E
A
L
E
N
L
G
S
L
Y
N
P
I
F
I
Y
G
S
V
G
T
G
K
T
H
L
L
Q
A
A
G
N
E
A
K
--
K
R
--
G
--
Y
R
---
V
I
Y
S
S
A
D
D
F
A
--
Q
A
M
V
E
H
L
K
K
G
T
I
N
E
F
R
-
N
M
---
Y
-
K
-
S
-
V
D
L
L
L
L
D
D
V
Q
F
L
S
G
K
E
R
T
Q
I
E
F
F
H
I
F
N
T
L
Y
L
L
E
K
Q
I
I
L
A
S
D
R
H
P
Q
K
L
D
G
--
V
S
D
R
L
V
S
R
F
E
G
G
I
L
V
E
I
-
E
L
D
N
K
T
R
F
K
I
I
K
E
K
L
K
E
F
N
L
E
L
R
K
E
V
I
D
Y
L
L
E
N
-
T
K
N
V
R
E
I
E
G
K
I
K
L
I
K
L
K
G
---------------
F
E
G
L
E
R
K
E
R
K
E
R
D
K
L
M
Q
I
V
E
F
V
A
N
Y
Y
A
V
K
V
E
D
I
L
S
D
K
-
N
K
R
T
S
E
A
R
K
I
A
M
Y
L
C
R
K
V
C
S
A
S
L
I
E
I
A
R
A
F
K
R
K
D
H
T
T
V
I
H
A
I
R
S
V
----
E
E
E
K
R
K
F
K
H
L
V
G
F
L
E
K
Q
A
F
D
K
I
C
----------
23
PsiBlast_CBE
89.83
34%
-88
- C2 -
2HCB
2
DNAA_AQUAE
D:
[7-301]
-----------------------------------------------------------------------------------------------------------------
Y
T
L
E
N
F
I
V
G
E
G
N
R
L
A
Y
E
V
V
K
E
A
L
E
N
L
G
S
L
Y
N
P
I
F
I
Y
G
S
V
G
T
G
K
T
H
L
L
Q
A
A
G
N
E
A
K
--
K
R
--
G
--
Y
R
---
V
I
Y
S
S
A
D
D
F
A
--
Q
A
M
V
E
H
L
K
K
G
T
I
N
E
F
R
-
N
M
---
Y
-
K
-
S
-
V
D
L
L
L
L
D
D
V
Q
F
L
S
G
K
E
R
T
Q
I
E
F
F
H
I
F
N
T
L
Y
L
L
E
K
Q
I
I
L
A
S
D
R
H
P
Q
K
L
D
G
--
V
S
D
R
L
V
S
R
F
E
G
G
I
L
V
E
I
-
E
L
D
N
K
T
R
F
K
I
I
K
E
K
L
K
E
F
N
L
E
L
R
K
E
V
I
D
Y
L
L
E
N
-
T
K
N
V
R
E
I
E
G
K
I
K
L
I
K
L
K
G
---------------
F
E
G
L
E
R
K
E
R
K
E
R
D
K
L
M
Q
I
V
E
F
V
A
N
Y
Y
A
V
K
V
E
D
I
L
S
D
K
-
N
K
R
T
S
E
A
R
K
I
A
M
Y
L
C
R
K
V
C
S
A
S
L
I
E
I
A
R
A
F
K
R
K
D
H
T
T
V
I
H
A
I
R
S
V
----
E
E
E
K
K
R
K
F
K
H
L
V
G
F
L
E
K
Q
A
F
D
K
I
C
---------
4
PsiBlast_PDB
89.26
34%
-84
- C2 -
2HCB
3
DNAA_AQUAE
A:
[7-301]
-----------------------------------------------------------------------------------------------------------------
Y
T
L
E
N
F
I
V
G
E
G
N
R
L
A
Y
E
V
V
K
E
A
L
E
N
L
G
S
L
Y
N
P
I
F
I
Y
G
S
V
G
T
G
K
T
H
L
L
Q
A
A
G
N
E
A
K
--
K
R
--
G
--
Y
R
---
V
I
Y
S
S
A
D
D
F
A
--
Q
A
M
V
E
H
L
K
K
G
T
I
N
E
F
R
-
N
M
---
Y
-
K
-
S
-
V
D
L
L
L
L
D
D
V
Q
F
L
S
G
K
E
R
T
Q
I
E
F
F
H
I
F
N
T
L
Y
L
L
E
K
Q
I
I
L
A
S
D
R
H
P
Q
K
L
D
G
--
V
S
D
R
L
V
S
R
F
E
G
G
I
L
V
E
I
-
E
L
D
N
K
T
R
F
K
I
I
K
E
K
L
K
E
F
N
L
E
L
R
K
E
V
I
D
Y
L
L
E
N
-
T
K
N
V
R
E
I
E
G
K
I
K
L
I
K
L
K
G
---------------
F
E
G
L
E
R
K
E
R
K
E
R
D
K
L
M
Q
I
V
E
F
V
A
N
Y
Y
A
V
K
V
E
D
I
L
S
D
K
R
--
R
T
S
E
A
R
K
I
A
M
Y
L
C
R
K
V
C
S
A
S
L
I
E
I
A
R
A
F
K
--
D
H
T
T
V
I
H
A
I
R
S
V
----
E
E
E
K
K
R
K
F
K
H
L
V
G
F
L
E
K
Q
A
F
D
K
I
C
---------
24
PsiBlast_CBE
88.86
34%
-86
- C2 -
2HCB
3
DNAA_AQUAE
C:
[7-301]
-----------------------------------------------------------------------------------------------------------------
Y
T
L
E
N
F
I
V
G
E
G
N
R
L
A
Y
E
V
V
K
E
A
L
E
N
L
G
S
L
Y
N
P
I
F
I
Y
G
S
V
G
T
G
K
T
H
L
L
Q
A
A
G
N
E
A
K
--
K
R
--
G
--
Y
R
---
V
I
Y
S
S
A
D
D
F
A
--
Q
A
M
V
E
H
L
K
K
G
T
I
N
E
F
R
-
N
M
---
Y
-
K
-
S
-
V
D
L
L
L
L
D
D
V
Q
F
L
S
G
K
E
R
T
Q
I
E
F
F
H
I
F
N
T
L
Y
L
L
E
K
Q
I
I
L
A
S
D
R
H
P
Q
K
L
D
G
--
V
S
D
R
L
V
S
R
F
E
G
G
I
L
V
E
I
-
E
L
D
N
K
T
R
F
K
I
I
K
E
K
L
K
E
F
N
L
E
L
R
K
E
V
I
D
Y
L
L
E
N
-
T
K
N
V
R
E
I
E
G
K
I
K
L
I
K
L
K
G
---------------
F
E
G
L
E
R
K
E
R
K
E
R
D
K
L
M
Q
I
V
E
F
V
A
N
Y
Y
A
V
K
V
E
D
I
L
S
D
K
-
N
K
R
T
S
E
A
R
K
I
A
M
Y
L
C
R
K
V
C
S
A
S
L
I
E
I
A
R
A
F
---
D
H
T
T
V
I
H
A
I
R
S
V
----
E
E
E
K
K
R
K
F
K
H
L
V
G
F
L
E
K
Q
A
F
D
K
I
C
---------
22
PsiBlast_CBE
86.81
39%
-94
- C2 -
2Z4R
2
DNAA_THEMA
B:
[96-335]
-----------------------------------------------------------------------------------------------------------
T
P
L
N
P
D
Y
T
F
E
N
F
V
V
G
P
G
N
S
F
A
Y
H
A
A
L
E
V
A
K
H
P
G
R
-
Y
N
P
L
F
I
Y
G
G
V
G
L
G
K
T
H
L
L
Q
S
I
G
N
Y
V
V
QN
E
P
--
D
--
L
R
---
V
M
Y
I
T
S
E
K
F
L
--
N
D
L
V
D
S
M
K
E
G
K
L
N
E
F
R
-
E
K
---
Y
-
R
-
K
K
V
D
I
L
L
I
D
D
V
Q
F
L
I
G
K
T
G
V
Q
T
E
L
F
H
T
F
N
E
L
H
D
S
G
K
Q
I
V
I
C
S
D
R
E
P
Q
K
L
S
E
--
F
Q
D
R
L
V
S
R
F
Q
M
G
L
V
A
K
L
E
P
P
D
E
E
T
R
K
S
I
A
R
K
M
L
E
I
E
H
G
E
L
P
E
E
V
L
N
F
V
A
E
N
V
D
D
N
L
R
R
L
R
G
A
I
I
K
L
L
V
Y
K
E
T
T
G
K
E
V
D
L
K
E
A
I
L
L
L
K
D
F
I
-
K
P
----------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
86.74
39%
-93
- C2 -
2Z4R
2
DNAA_THEMA
A:
[96-335]
-----------------------------------------------------------------------------------------------------------
T
P
L
N
P
D
Y
T
F
E
N
F
V
V
G
P
G
N
S
F
A
Y
H
A
A
L
E
V
A
K
H
P
G
R
-
Y
N
P
L
F
I
Y
G
G
V
G
L
G
K
T
H
L
L
Q
S
I
G
N
Y
V
V
Q
N
E
P
--
D
--
L
R
---
V
M
Y
I
T
S
E
K
F
L
--
N
D
L
V
D
S
M
K
E
G
K
L
N
E
F
R
-
E
K
---
Y
-
R
-
K
K
V
D
I
L
L
I
D
D
V
Q
F
L
I
G
K
T
G
V
Q
T
E
L
F
H
T
F
N
E
L
H
D
S
G
K
Q
I
V
I
C
S
D
R
E
P
Q
K
L
S
E
--
F
Q
D
R
L
V
S
R
F
Q
M
G
L
V
A
K
L
E
P
P
D
E
E
T
R
K
S
I
A
R
K
M
L
E
I
E
H
G
E
L
P
E
E
V
L
N
F
V
A
E
N
V
D
D
N
L
R
R
L
R
G
A
I
I
K
L
L
V
Y
K
E
T
T
G
K
E
V
D
L
K
E
A
I
L
L
L
K
D
F
I
-
K
P
----------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
86.72
39%
-94
- C2 -
2Z4R
2
DNAA_THEMA
C:
[96-335]
-----------------------------------------------------------------------------------------------------------
T
P
L
N
P
D
Y
T
F
E
N
F
V
V
G
P
G
N
S
F
A
Y
H
A
A
L
E
V
A
K
H
P
G
R
-
Y
N
P
L
F
I
Y
G
G
V
G
L
G
K
T
H
L
L
Q
S
I
G
N
Y
V
V
QN
E
P
--
D
--
L
R
---
V
M
Y
I
T
S
E
K
F
L
--
N
D
L
V
D
S
M
K
E
G
K
L
N
E
F
R
-
E
K
---
Y
-
R
-
K
K
V
D
I
L
L
I
D
D
V
Q
F
L
I
G
K
T
G
V
Q
T
E
L
F
H
T
F
N
E
L
H
D
S
G
K
Q
I
V
I
C
S
D
R
E
P
Q
K
L
S
E
--
F
Q
D
R
L
V
S
R
F
Q
M
G
L
V
A
K
L
E
P
P
D
E
E
T
R
K
S
I
A
R
K
M
L
E
I
E
H
G
E
L
P
E
E
V
L
N
F
V
A
E
N
V
D
D
N
L
R
R
L
R
G
A
I
I
K
L
L
V
Y
K
E
T
T
G
K
E
V
D
L
K
E
A
I
L
L
L
K
D
F
I
-
K
P
----------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
84.82
39%
-93
- C2 -
2Z4S
2
DNAA_THEMA
A:
[96-335]
-----------------------------------------------------------------------------------------------------------
T
P
L
N
P
D
Y
T
F
E
N
F
V
V
G
P
G
N
S
F
A
Y
H
A
A
L
E
V
A
K
H
P
G
R
-
Y
N
P
L
F
I
Y
G
G
V
G
L
G
K
T
H
L
L
Q
S
I
G
N
Y
V
V
Q
N
E
P
--
D
--
L
R
---
V
M
Y
I
T
S
E
K
F
L
--
N
D
L
V
D
S
M
K
E
G
K
L
N
E
F
R
-
E
K
---
Y
-
R
-
K
K
V
D
I
L
L
I
D
D
V
Q
F
L
I
G
K
T
G
V
Q
T
E
L
F
H
T
F
N
E
L
H
D
S
G
K
Q
I
V
I
C
S
D
R
E
P
Q
K
L
S
E
--
F
Q
D
R
L
V
S
R
F
Q
M
G
L
V
A
K
L
E
P
P
D
E
E
T
R
K
S
I
A
R
K
M
L
E
I
E
H
G
E
L
P
E
E
V
L
N
F
V
A
E
N
V
D
D
N
L
R
R
L
R
G
A
I
I
K
L
L
V
Y
K
E
T
T
G
K
E
V
D
L
K
E
A
I
L
L
L
K
D
F
I
-
K
P
----------------------------------------------------------------------------------------------------------------
41
HHSearch
81.78
32%
-92
- C2 -
2Z4S
2
DNAA_THEMA
A:
[96-335]
-----------------------------------------------------------------------------------------------------------
T
P
L
N
P
D
Y
T
F
E
N
F
V
V
G
P
G
N
S
F
A
Y
H
A
A
L
E
V
A
K
H
P
G
-
R
Y
N
P
L
F
I
Y
G
G
V
G
L
G
K
T
H
L
L
Q
S
I
G
N
Y
V
V
--
Q
N
EP
D
--
L
R
---
V
M
Y
I
T
S
E
K
F
L
--
N
D
L
V
D
S
M
K
E
G
K
L
N
E
F
R
-
E
K
---
Y
-
R
K
K
-
V
D
I
L
L
I
D
D
V
Q
F
L
I
G
K
T
G
V
Q
T
E
L
F
H
T
F
N
E
L
H
D
S
G
K
Q
I
V
I
C
S
D
R
E
P
Q
K
L
S
E
--
F
Q
D
R
L
V
S
R
F
Q
M
G
L
V
A
K
L
E
P
P
D
E
E
T
R
K
S
I
A
R
K
M
L
E
I
E
H
G
E
L
P
E
E
V
L
N
F
V
A
E
N
V
D
D
N
L
R
R
L
R
G
A
I
I
K
L
L
V
Y
K
E
T
T
G
K
E
V
D
L
K
E
A
I
L
L
L
K
D
F
I
-
K
P
----------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
62.15
22%
-77
- C2 -
3SC3
2
?
A:
[14-196]
-----------------------------------------------------------------------------------------------------------------------
Y
P
A
A
G
N
D
E
L
I
G
A
L
K
S
A
A
S
G
D
G
--
V
Q
A
I
Y
L
W
G
P
V
K
S
G
R
T
H
L
I
H
A
A
C
A
R
A
N
--
E
L
--
E
--
R
R
S
F
Y
I
P
L
G
I
H
A
S
I
S
--
T
A
L
L
E
G
L
E
Q
-------------------
F
D
L
I
C
I
D
D
V
D
A
V
A
G
H
P
L
W
E
E
A
I
F
D
L
Y
N
R
V
A
E
Q
K
R
G
S
L
I
V
S
A
S
A
S
P
M
E
A
G
FV
L
P
D
-
L
V
S
R
M
H
W
G
L
T
Y
Q
L
Q
P
M
M
D
D
E
K
L
A
A
L
Q
R
R
A
A
M
R
G
L
Q
L
P
E
D
V
G
R
F
L
L
N
R
M
A
R
D
L
R
T
L
F
D
V
L
D
R
L
D
K
A
S
M
V
H
Q
R
K
L
T
I
P
F
V
K
E
M
L
R
L
---------------------------------------------------------------------------------------------------------------------
36
Fugue
61.88
96%
-89
- C1 -
2WP0
-
DNAA_HELPY
C:
[6-91]
-----
N
I
E
K
E
I
L
A
L
V
K
Q
N
P
K
V
S
L
I
E
Y
E
N
Y
F
S
Q
L
K
Y
N
P
N
A
S
K
S
D
I
A
F
F
Y
A
P
N
Q
V
L
C
T
T
I
T
A
K
Y
G
A
L
L
K
E
I
L
S
Q
N
K
-
G
M
H
L
A
H
S
V
D
V
R
I
E
V
A
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
61.69
95%
-89
- C1 -
2WP0
-
DNAA_HELPY
C:
[6-91]
-----
N
I
E
K
E
I
L
A
L
V
K
Q
N
P
K
V
S
L
I
E
Y
E
N
Y
F
S
Q
L
K
Y
N
P
N
A
S
K
S
D
I
A
F
F
Y
A
P
N
Q
V
L
C
T
T
I
T
A
K
Y
G
A
L
L
K
E
I
L
S
Q
N
K
-
G
M
H
L
A
H
S
V
D
V
R
I
E
V
A
P
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
HHSearch
60.05
14%
-91
- C2 -
1IQP
1
RFCS_PYRFU
A:
[23-241]
------------------------------------------------------------------------------------------------------------------
R
L
D
D
I
V
---
G
Q
E
H
I
V
K
R
L
K
H
Y
V
K
T
G
--
S
M
P
H
L
L
F
A
G
P
P
G
V
G
K
T
T
A
A
L
A
L
A
R
E
L
F
--
G
E
NW
R
--
H
N
---
F
L
E
L
N
A
S
D
E
R
--
G
--
I
N
V
I
R
E
-
K
V
K
E
F
A
-
R
T
KPI
G
G
A
-
S
-
F
K
I
I
F
L
D
E
A
D
A
L
T
--
Q
D
A
Q
Q
A
L
R
R
T
M
E
M
F
S
-
S
N
V
R
F
I
L
S
C
N
Y
S
S
----
K
--
I
I
E
P
I
Q
S
R
C
A
---
I
F
R
F
R
P
L
R
D
E
D
I
A
K
R
L
R
Y
I
A
E
N
E
G
L
E
L
T
E
E
G
L
Q
A
I
L
Y
I
A
E
G
D
M
R
R
A
I
N
I
L
Q
A
A
A
A
L
D
K
----
K
I
T
D
E
N
V
F
M
V
A
S
R
A
R
-
P
E
D
I
R
E
M
M
L
L
A
L
K
G
N
F
L
K
A
R
E
K
L
R
E
I
L
L
K
Q
G
L
S
G
E
D
V
L
V
Q
M
H
K
E
V
F
N
L
P
I
E
E
P
K
K
V
L
L
A
D
K
I
G
E
Y
N
F
R
L
V
E
G
A
N
E
I
I
Q
L
E
A
L
L
A
Q
F
T
L
I
G
K
K
----------------------
59
HHSearch
59.72
13%
-91
* C2 *
1SXJ
4
RFC4_YEAST
B:
[19-230]
------------------------------------------------------------------------------------------------------------------
V
L
S
D
I
V
---
G
N
K
E
T
I
D
R
L
Q
Q
I
A
K
D
G
--
N
M
P
H
M
I
I
S
G
M
P
G
I
G
K
T
T
S
V
H
C
L
A
H
E
L
L
--
G
R
--
S
YA
D
G
---
V
L
E
L
N
A
S
D
D
R
G
I
D
V
V
R
N
Q
I
K
H
-
F
A
Q
K
K
L
H
L
P
---
P
-
G
-
K
-
H
K
I
V
I
L
D
E
A
D
S
M
T
A
--
G
A
Q
Q
A
L
R
R
T
M
E
L
Y
S
N
-
S
T
R
F
A
F
A
C
N
Q
S
----
N
K
--
I
I
E
P
L
Q
S
Q
C
A
---
I
L
R
Y
S
K
L
S
D
E
D
V
L
K
R
L
L
Q
I
I
K
L
E
D
V
K
Y
T
N
D
G
L
E
A
I
I
F
T
A
E
G
D
M
R
Q
A
I
N
N
L
Q
S
T
V
A
G
H
G
----
L
V
N
A
D
N
V
F
K
I
V
D
S
P
H
-
P
L
I
V
K
K
M
L
L
A
S
N
L
E
D
S
I
Q
I
L
R
T
D
L
W
K
K
G
Y
S
S
I
D
I
V
T
T
S
F
R
V
T
K
N
L
A
Q
V
K
E
S
V
R
L
E
M
I
K
E
I
G
L
T
H
M
R
I
L
E
G
V
G
T
Y
L
Q
L
A
S
M
L
A
K
I
H
K
L
N
N
K
------------------------