@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : jhp_1419: (2015-12-23 )
MFEKIRKILADIEDSQNEIEMLLKLANLSLGDFIEIKRGSMDMPKGVNEAFFTQLSEEVERLKELINALNKIKKGLLVF
Atome Classification :
(20 SA)
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10...-----.....20--.........30-------........40.-.......50........60........70........-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
F
E
K
I
R
K
I
L
A
DIED-----
S
Q
N
E
I
E
---
M
L
L
K
L
A
NLSLG-------
D
F
I
E
I
KRGSMD-MPKGV
N
E
A
F
F
T
Q
L
S
E
E
V
E
R
L
K
E
L
I
N
A
L
N
K
I
K
KGLLVF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_CBE
99.33
100%
-149
- C3 -
1ZKE
1
Y1531_HELPY
C:
[3-81]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
F
E
K
I
R
K
I
L
A
D
I
E
D
-----
S
Q
N
E
I
E
---
M
L
L
K
L
A
N
L
S
L
G
-------
D
F
I
E
I
K
R
G
S
M
D
-
M
P
K
G
V
N
E
A
F
F
T
Q
L
S
E
E
V
E
R
L
K
E
L
I
N
A
L
N
K
I
K
K
G
L
L
V
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_CBE
99.24
100%
-152
- C3 -
1ZKE
1
Y1531_HELPY
B:
[3-81]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
F
E
K
I
R
K
I
L
A
D
I
E
D
-----
S
Q
N
E
I
E
---
M
L
L
K
L
A
N
L
S
L
G
-------
D
F
I
E
I
K
R
G
S
M
D
-
M
P
K
G
V
N
E
A
F
F
T
Q
L
S
E
E
V
E
R
L
K
E
L
I
N
A
L
N
K
I
K
K
G
L
L
V
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_CBE
98.69
100%
-147
- C3 -
1ZKE
1
Y1531_HELPY
E:
[3-81]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
F
E
K
I
R
K
I
L
A
D
I
E
D
-----
S
Q
N
E
I
E
---
M
L
L
K
L
A
N
L
S
L
G
-------
D
F
I
E
I
K
R
G
S
M
D
-
M
P
K
G
V
N
E
A
F
F
T
Q
L
S
E
E
V
E
R
L
K
E
L
I
N
A
L
N
K
I
K
K
G
L
L
V
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
98.35
100%
-142
- C3 -
1ZKE
-
Y1531_HELPY
A:
[3-81]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
F
E
K
I
R
K
I
L
A
D
I
E
D
-----
S
Q
N
E
I
E
---
M
L
L
K
L
A
N
L
S
L
G
-------
D
F
I
E
I
K
R
G
S
M
D
-
M
P
K
G
V
N
E
A
F
F
T
Q
L
S
E
E
V
E
R
L
K
E
L
I
N
A
L
N
K
I
K
K
G
L
L
V
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
98.35
100%
-142
- C3 -
1ZKE
-
Y1531_HELPY
A:
[3-81]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
F
E
K
I
R
K
I
L
A
D
I
E
D
-----
S
Q
N
E
I
E
---
M
L
L
K
L
A
N
L
S
L
G
-------
D
F
I
E
I
K
R
G
S
M
D
-
M
P
K
G
V
N
E
A
F
F
T
Q
L
S
E
E
V
E
R
L
K
E
L
I
N
A
L
N
K
I
K
K
G
L
L
V
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
43
Fugue
98.34
100%
-142
- C3 -
1ZKE
-
Y1531_HELPY
A:
[3-83]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
F
E
K
I
R
K
I
L
A
D
I
E
D
-----
S
Q
N
E
I
E
---
M
L
L
K
L
A
N
L
S
L
G
-------
D
F
I
E
I
K
R
G
S
M
D
-
M
P
K
G
V
N
E
A
F
F
T
Q
L
S
E
E
V
E
R
L
K
E
L
I
N
A
L
N
K
I
K
K
G
L
L
V
F
GS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47
Fugue
55.97
32%
-82
- C3 -
2LSE
-
?
A:
[1-101]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQEE
R
K
K
L
L
E
K
L
E
K
I
L
D
E
V
T
D
G
APDE
A
R
E
R
I
E
---
K
L
A
K
D
V
K
D
E
L
E
EGD
A
K
--
N
M
I
E
K
F
R
D
E
M
E
Q
M
Y
K
D
A
P
N
A
V
M
E
Q
L
L
E
E
I
E
K
L
L
K
K
A
G
S
L
V
P
R
G
S
Y
L
E
H
H
HHHH-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
Fugue
55.18
21%
-68
- C3 -
4BUJ
3
SKI3_YEAST
B:
[3-1436]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DS
M
S
D
I
K
Q
L
L
K
E
A
K
Q
E
L
T
N
RD
Y
E
E
T
I
E
I
S
E
K
V
L
K
L
D
PDN
Y
F
A
H
I
F
L
G
K
A
L
S
S
LPASN
N
V
S
S
N
R
N
L
E
R
A
T
N
H
Y
V
S
A
A
K
L
V
PDN
L
L
A
W
K
G
L
F
L
L
F
R
T
T
E
V
V
P
D
I
L
S
Y
D
E
Y
F
D
L
C
G
Q
Y
A
D
A
L
L
K
Q
EQ
V
E
L
I
N
D
I
K
L
L
K
K
T
H
PDC
Q
K
A
F
Y
Q
H
L
KPGS
L
M
A
E
T
IGRT
P
Q
D
A
L
L
N
L
I
K
I
L
S
N
I
E
T
T
E
I
G
K
T
L
S
Q
N
R
L
K
LKASDPD
Y
Q
I
K
L
N
S
F
S
W
E
I
I
K
N
SE
I
D
Q
L
Y
N
Q
L
V
N
I
L
A
D
D
Q
K
-----
R
S
E
I
E
N
---
Q
W
L
E
Y
R
I
K
V
L
K
-------
S
-----------
M
P
L
D
V
K
K
D
F
F
T
K
V
K
E
M
V
E
D
M
V
L
V
N
H
Q
S
L
L
A
W
Q
K
Y
F
E
W
TDYEDLDNMDA
P
L
I
I
K
Y
F
K
K
FPKD
P
L
A
M
I
L
Y
S
W
L
S
SKLSKYD
I
K
S
L
E
SDDIEIGLL
E
E
E
V
V
T
V
L
T
E
N
I
V
K
C
KNN
I
L
A
H
R
I
L
C
Q
Y
Y
L
L
T
KEYEAA
L
P
Y
I
K
N
G
I
S
L
I
A
Y
N
I
K
D
LGVHL
P
L
T
K
R
E
F
S
L
D
L
A
T
V
Y
T
YVDAPKD
H
N
A
A
L
K
L
Y
D
N
I
L
S
GDFSN
I
Q
A
K
M
G
K
G
I
I
F
I
E
R
KNW
K
D
A
M
T
L
L
T
Q
V
H
E
Q
SPNN
L
E
V
L
S
E
L
S
W
S
K
A
H
M
GY
M
D
E
A
L
A
G
L
D
T
V
I
K
G
I
KGMD
L
R
S
I
D
F
R
A
L
N
L
W
R
Q
A
K
V
Y
I
M
K
H
A
SAKQE
N
V
K
C
A
F
K
L
L
I
Q
S
I
K
I
LDTF
A
P
G
F
S
T
L
G
D
I
Y
C
HYYKD
H
L
R
A
F
K
C
Y
F
K
A
F
D
L
DAGD
Y
T
A
A
K
Y
I
T
E
T
Y
A
S
K
PN
W
Q
A
A
S
S
I
A
S
R
L
I
K
G
EKA
K
A
E
L
R
S
NN
W
P
F
R
V
V
G
I
A
H
L
E
K
QE
E
S
D
S
I
E
W
F
Q
S
A
L
R
V
DPND
V
E
S
W
V
G
L
G
Q
A
Y
H
A
C
GR
I
E
A
S
I
K
V
F
D
K
A
I
Q
L
RPSH
T
F
A
Q
Y
F
K
A
I
S
L
C
D
V
GE
Y
L
E
S
L
D
I
L
E
K
V
C
Q
E
AATEE
S
F
Q
I
G
L
V
E
V
L
M
R
C
S
L
D
L
Y
S
Q
GF
L
L
K
S
V
S
I
A
K
D
T
I
E
R
I
K
I
I
I
S
E
LKCENQQ
V
W
I
Y
L
S
Q
V
L
R
L
F
I
W
I
ESKVDTLP
V
E
S
L
V
S
I
F
E
N
S
QFSGS
E
E
I
D
S
V
DNIKIDTLLDSTTDD
N
V
S
I
A
C
K
F
L
I
L
A
S
K
Y
SVSDQK
F
T
D
I
AG
T
V
R
A
S
Y
W
Y
N
I
G
I
S
E
L
T
A
F
I
T
L
KE
P
Q
Y
R
D
A
A
I
F
A
F
K
K
S
I
Q
L
QSNT
S
E
T
W
I
G
L
G
I
A
T
MDIN
F
R
V
S
Q
H
C
F
I
K
A
T
A
L
EPKA
T
N
T
W
F
N
L
A
M
L
G
L
K
K
KD
T
E
F
A
Q
Q
V
L
N
K
L
Q
S
L
APQD
S
S
P
W
L
G
M
A
L
I
L
E
E
Q
GD
I
I
G
S
S
K
L
F
A
H
S
F
I
L
S
N
GRS
K
A
A
Q
F
M
Y
A
K
N
V
L
E
N
HINNGDDERD
I
E
T
V
E
K
L
T
T
A
S
I
A
L
E
Q
F
F
K
K
SPDS
Q
F
A
L
Q
C
A
L
L
T
L
E
R
L
HH
Y
E
N
A
N
E
L
A
N
R
L
I
G
I
L
E
K
K
F
E
K
TQD
E
R
E
L
F
N
F
A
I
I
K
G
Q
F
A
R
I
H
L
G
L
GN
F
E
L
S
I
E
N
A
D
L
S
Q
G
I
I
SESSD
E
K
S
M
K
T
K
I
S
N
H
I
C
L
G
L
S
Y
F
F
L
NDF
D
Q
T
L
N
Q
F
Q
E
L
L
S
I
S
KDS
K
H
L
V
V
L
I
A
K
V
L
Y
D
V
GE
S
D
T
K
E
I
A
L
Q
E
L
T
E
Y
I
A
T
SGADL
L
V
T
L
T
I
A
A
M
S
I
L
D
DK
R
E
D
L
S
I
I
L
E
E
L
K
A
LP
L
S
K
Q
I
I
DKHK
D
A
P
Y
L
I
E
E
I
T
K
R
L
YRNDTGK
Q
V
W
Q
R
S
A
Y
F
FPNN
L
K
V
W
E
R
LD
K
N
I
Q
R
R
I
A
SNGQ
N
K
V
T
A
E
E
M
S
K
L
Y
C
E
S
KN
L
R
S
I
Q
R
G
M
F
L
C
PWN
V
T
A
V
K
A
L
N
E
C
F
46
Fugue
53.56
17%
-100
- C3 -
4WD8
4
?
A:
[25-292]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SK
I
I
F
R
L
L
L
N
V
L
M
S
I
I
A
I
I
S
YQWYEQLG
I
H
L
T
V
A
P
F
S
L
L
G
I
A
I
A
I
F
L
G
F
R
N
S
A
S
Y
S
R
F
V
E
A
R
N
L
W
G
T
V
L
I
A
E
R
T
L
V
R
Q
L
R
N
I
LPAE
H
D
A
H
R
R
I
V
S
Y
L
V
A
F
S
W
S
L
K
H
Q
L
R
KTDP
T
A
D
L
R
R
L
L
P
E
E
R
V
T
E
I
L
A
---------
S
S
M
P
T
N
---
R
I
L
L
L
A
G
N
E
I
G
-------
Q
L
R
E
---------
A
G
K
L
S
D
I
T
Y
G
L
M
D
N
K
L
D
E
L
A
H
V
L
G
G
C
E
R
L
A
T
T
P
V
P
F
A
Y
T
L
I
L
Q
R
T
V
Y
L
F
C
T
L
LPFALVGDLHYM
T
P
F
V
S
V
F
I
S
Y
T
F
L
S
W
D
S
L
A
E
E
L
E
D
PFGTAANDLP
L
N
A
M
C
N
T
I
E
R
N
L
L
D
M
T
GQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
Fugue
53.16
16%
-60
- C3 -
3SJA
-
GET1_YEAST
C:
[1-61]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
E
L
S
K
K
Y
L
A
-----
K
V
K
E
R
H
---
E
L
K
E
F
N
N
---------------------
S
-
I
S
A
Q
D
N
Y
A
K
W
T
K
N
N
R
K
L
D
S
L
D
K
E
I
N
N
L
K
D
E
I
Q
S
E
N
H
H
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
Fugue
52.33
23%
-52
- C3 -
1WA8
-
B:
[601-695]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTEQQW
N
F
A
G
I
E
A
A
A
S
A
I
Q
G
-----
N
V
T
S
I
H
---
S
L
L
D
E
G
K
Q
S
L
T
-------
K
L
A
A
A
W
G
G
S
G
-------
S
E
A
Y
Q
G
V
Q
Q
K
W
D
A
T
A
T
E
L
N
N
A
L
Q
N
L
A
R
T
I
S
E
A
GQAMASTEGNVTGMFA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
Fugue
47.38
20%
-49
- C3 -
4W8J
3
CR1AC_BACTK
A:
[33-1178]
YT
P
I
D
I
S
L
S
L
T
Q
F
L
L
S
EFVPG
A
G
F
V
L
G
L
V
D
I
IWGIFG
P
S
Q
W
D
A
F
L
V
Q
I
E
Q
L
I
NQRIE
E
F
A
R
N
Q
A
I
S
R
L
E
G
L
S
N
L
Y
Q
I
Y
A
E
S
F
R
E
W
E
A
DPTN
P
A
L
R
E
E
M
R
I
Q
F
N
D
M
N
S
A
L
T
T
A
I
P
L
L
A
VQNYQVPL
L
S
V
Y
V
Q
A
A
N
L
H
L
S
V
L
R
D
V
S
V
FGQRWGFD
A
A
T
I
N
S
R
Y
N
D
L
T
R
L
I
G
N
Y
T
D
Y
A
V
R
W
Y
N
T
G
L
E
R
V
WGPD
S
R
D
W
V
R
Y
N
Q
F
R
R
E
L
T
L
T
V
L
D
I
V
A
L
FPNYDSRRYP
I
R
T
V
S
Q
L
T
R
E
I
Y
T
N
P
V
L
E
N
FD
G
S
F
R
GS
A
Q
G
I
E
R
S
IRSPHL
M
D
I
L
N
S
I
T
I
Y
T
D
A
H
RGYYYWS
G
H
Q
I
M
A
S
P
VGFSG
P
E
F
T
F
P
LYGTMGNA
A
P
Q
Q
R
I
V
A
QLGQGVY
R
T
L
S
S
T
L
Y
R
R
P
F
NQ
Q
L
S
V
L
D
G
T
E
F
A
Y
G
T
S
S
N
L
P
S
AVYRKSGTVDSLDEIPPQNNNVPPRQGFSHRLS
H
V
S
M
F
R
S
G
FVSIIR
A
P
M
F
S
W
I
H
RSAEVNNIIASD
S
I
T
Q
I
P
AVKGNFLFN
G
S
V
I
S
GPGFTG
G
D
L
V
R
L
N
S
SNIQN
R
G
Y
I
E
V
P
I
H
F
PSTS
T
R
Y
R
V
R
V
R
Y
A
S
V
T
P
I
H
L
N
V
N
W
GNSSI
F
S
N
T
V
P
A
TATSLDNLQSSD
F
G
Y
F
E
S
ANAFTGN
I
V
G
V
R
NFSG
T
A
G
V
I
I
D
R
F
E
F
I
P
V
T
A
T
L
E
A
E
Y
N
L
E
R
A
Q
K
A
V
N
A
L
F
TSTNQLGLKTNVT
D
Y
H
I
D
Q
V
S
N
L
V
T
Y
LSDEFS
L
D
E
K
R
E
L
S
E
K
V
K
H
A
K
R
L
S
D
E
R
NLLQDSNFKDINRER
G
W
G
G
S
T
G
I
T
I
Q
GGDDVFK
E
N
Y
V
T
L
S
G
T
FDESY
P
T
Y
L
Y
Q
K
I
D
ESKLKAF
T
R
Y
Q
L
R
G
Y
I
E
D
S
Q
D
L
E
I
Y
L
I
R
Y
N
A
K
H
E
T
V
N
V
P
G
T
G
SSAHHSH
H
F
S
L
D
I
D
V
G
STDLNEDL
G
V
W
V
I
F
K
I
KTQD
G
H
A
R
L
G
N
L
E
F
L
E
E
K
PLVG
E
A
L
A
R
V
K
R
A
E
K
K
W
R
D
K
R
E
K
L
E
W
E
T
N
I
V
Y
K
E
A
K
E
S
V
D
A
L
F
V
N
S
Q
Y
-----
D
Q
L
Q
A
D
TN
I
A
M
I
H
A
A
D
K
R
V
H
-------
S
I
R
E
A
Y
L
P
E
L
S
-
V
I
P
G
V
N
A
A
I
F
E
E
L
E
G
R
I
F
T
A
F
S
L
Y
D
A
R
N
V
I
K
N
G
D
F
N
N
GLSS
W
N
V
K
G
H
V
D
V
E
E
Q
NNQ
R
S
V
L
V
VPEWE
A
E
V
S
Q
E
V
R
V
S
P
G
R
G
Y
I
L
R
V
T
A
Y
K
E
G
Y
G
E
G
S
V
T
I
H
E
IEN
N
T
D
E
L
K
F
S
NP
V
G
Y
V
T
K
E
L
E
Y
F
P
ETD
K
V
W
I
E
I
G
E
TE
G
T
F
I
V
D
S
V
E
L
L
L
MEE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
Fugue
45.68
19%
-60
- C3 -
3ZUY
10
?
A:
[2-309]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N
I
L
S
K
I
S
S
F
I
G
K
T
F
S
L
W
A
A
L
F
A
A
A
A
F
F
A
P
D
T
F
K
W
A
G
P
Y
I
P
-----
W
L
L
G
I
I
---
M
F
G
M
G
L
T
L
K
P
S
-------
D
F
D
I
L
F
K
H
P
K
V
-
V
I
I
G
V
-
I
A
Q
F
A
I
M
P
A
T
A
W
L
L
S
K
L
L
N
L
P
A
E
I
A
V
G
V
I
L
V
G
C
CPGG
T
A
S
N
V
M
T
Y
L
A
RGN
V
A
L
S
V
A
V
T
S
V
S
T
L
I
SP
L
L
T
P
A
I
F
L
M
L
A
GEML
E
I
Q
A
A
G
M
L
M
S
I
V
K
MV
L
L
P
I
V
L
G
L
I
V
H
K
V
L
GSKT
E
K
L
T
D
A
L
P
L
V
S
V
A
A
I
V
L
I
I
G
A
V
V
G
A
S
K
G
K
I
M
E
S
G
L
L
I
F
A
V
V
V
L
H
N
G
I
G
Y
L
L
G
F
F
A
A
K
W
T
GLP
Y
D
A
Q
K
T
L
T
I
E
V
G
MQN
S
G
L
A
A
A
L
A
A
A
HFAAAPVVA
V
P
G
A
L
F
S
V
W
H
N
I
S
G
S
L
L
A
T
Y
W
A
A
K
A-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
52
Fugue
42.40
12%
-43
- C3 -
4AJ5
-
SKA1_HUMAN
A:
[3-81]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
S
D
L
E
Q
L
C
S
H
V
N
E
-----
K
I
G
N
I
K
---
K
T
L
S
L
R
N
C
G
Q
E
-------
P
T
L
K
T
V
L
N
K
I
G
-
D
E
I
I
V
I
N
E
L
L
N
K
L
E
L
E
I
Q
Y
Q
E
Q
T
N
N
S
L
K
E
L
C
E
S
L
E
E
D
Y----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
40.11
43%
-63
- C3 -
4WLS
-
?
A:
[84-111]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
L
E
K
V
A
E
I
E
R
H
I
E
E
-----
L
Q
S
M
R
D
---
Q
L
L
A
L
A
N
A
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
39.22
31%
2
- C3 -
3J94
1
NSF_CRIGR
A:
[305-371]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
R
K
L
F
A
D
A
E
E
-----
E
Q
R
R
L
G
--------
A
N
S
G
L
H
I
I
I
F
D
EI
D
A
I
C
-------------
H
D
T
V
V
N
Q
L
L
S
K
I
D
G
V
E
Q
L
N
N
I
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
38.57
31%
-6
- C3 -
3J95
-
NSF_CRIGR
A:
[305-371]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
R
K
L
F
A
D
A
E
E
-----
E
Q
R
R
L
G
--------
A
N
S
G
L
H
I
I
I
F
D
EI
D
A
I
C
-------------
H
D
T
V
V
N
Q
L
L
S
K
I
D
G
V
E
Q
L
N
N
I
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
38.24
23%
-28
- C3 -
3OCE
3
?
A:
[167-231]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
H
R
L
I
A
A
F
E
A
-----
K
G
R
E
F
A
---
T
V
I
K
I
G
R
T
Q
L
Q
-------
D
A
V
P
I
T
L
G
Q
E
-------
F
E
A
F
A
A
T
L
R
E
D
T
A
R
L
E
E
V
A
A
L
F
R
E
V
N
L
G
G
T
A
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
37.57
42%
-44
- C3 -
1YF2
-
T1S1_METJA
A:
[178-203]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
T
K
I
D
E
G
I
E
I
I
E
K
S
I
N
K
L
E
R
I
K
K
G
L
M
H
K
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
37.33
23%
-27
- C3 -
3OCF
-
?
A:
[184-248]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
H
R
L
I
A
A
F
E
A
-----
K
G
R
E
F
A
---
T
V
I
K
I
G
R
T
Q
L
Q
-------
D
A
V
P
I
T
L
G
Q
E
-------
F
E
A
F
A
A
T
L
R
E
D
T
A
R
L
E
E
V
A
A
L
F
R
E
V
N
L
G
G
A
Y
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------