@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0005: (2016-03-11 )
MHLESIVLRNFRNYENLELEFSPSVNVFLGENAQGKTNLLEAVLMLALAKSHRTTNDKDFIMWEKEEAKMEGRIAKHGQSVPLELAITQKGKRAKVNHLEQKKLSQYVGNLNVVIFAPEDLSLVKGAPGIRRRFLNMEIGQMQPIYLHNLSEYQRILQQRNQYLKMLQMKRKVDPILLDILTEQFADVAINLTKRRADFIQKLEAYAAPIHHQISRGLETLKIEYKASITLNGDDPEVWKADLLQKMESIKQREIDRGVTLIGPHRDDSLFYINGQNVQDFGSQGQQRTTALSIKLAEIDLIHEETGEYPVLLLDDVLSELDDYRQSHLLGAIEGKVQTFVTTTSTSGIDHETLKQATTFYVEKGTVKKS
Atome Classification :
(20 SA)
----.........10-...-.-.....--20....-----....30.........40--..-..-----.....50.-------..-.-....60.....---------------------------------...70.....---------------...80........90--------........100---.........110--........120..-------.....130.-.......-140-.......150.......160......--.170.......180....---------...190........200.......210..-.....220-------..-.....230.....-..240.......250.......260.....----..270.......-----------280.....--------..290.......300...----....310.......320.......330...------------.-...340......--.350--...-....360.......370-------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----M
H
L
E
S
I
V
L
R
N--FRN-Y-
E
N
L
E
L
--
E
FSPS
V
-----
N
V
F
LG-ENAQG
K
T
N
L
L
---
E
A
-
V
L
-----
M
L
A
L
A
K
SH-------RT-T-NDK
D
F
I
M
W
E
K
E
---------------------------------
E
A
K
ME
G
R
I
A
K---------------HGQSV
P
L
E
L
A
ITQKG--------KR
A
K
V
N
H
L
E
-----
Q
K
K
L
S
Q
Y
VGNL---
N
V
V
I
FAPED
L
S
LV-------KGA
P
G
I
R
-
R
-
R
F
LNMEI-GQM-Q
P
I
Y
LH
N
L
S
E
Y
Q
R
I
L
Q
Q
R
N
Q
Y
L
K
M
L
Q
--
M
KRKV
D
P
I
L
L
D
I
L
T
E
Q
F
A
---------
D
V
A
I
N
-
L
T
K
R
R
A
D
F
I
Q
K
L
E
A
Y
A
A
P
I
H
H
Q
I
-
S
RGL
E
T
L
K
-------
I
E
-
Y
K
A
S
I
T
LNGD
D
P
E
-
V
W
K
A
D
L
L
Q
K
M
E
S
I
K
Q
R
E
IDR
G
V
T
L
IGPHRD----D
S
L
F
Y
INGQ
N
V
Q
-----------
D
F
GSQGQ
Q
--------
R
T
T
A
L
S
I
K
L
A
E
I
D
L
I
HEE----TGEY
P
V
L
L
L
D
D
V
L
S
E
L
D
D
Y
R
Q
S
H
L
L
G
A
IEG------------
K
-
V
Q
T
F
V
T
TTSTSG--I
D
H
E
--
T
L
K
-
Q
A
T
T
F
Y
V
EKGTVKKS---------------
1
PsiBlast_PDB
85.32
32%
-57
- C4 -
2O5V
1
RECF_DEIRA
A:
[4-345]
----
V
R
L
S
A
L
S
T
L
N
--
Y
R
N
-
L
-
A
P
G
T
L
--
N
F
P
E
G
V
-----
T
G
I
Y
G
-
E
N
G
A
G
K
T
N
L
L
---
E
A
-
A
------
Y
L
A
L
T
G
Q
T
-------
D
A
-
P
-
R
I
E
Q
L
I
Q
A
G
E
T
---------------------------------
E
A
Y
V
R
A
D
L
Q
Q
---------------
G
G
S
L
S
I
Q
E
V
G
L
G
R
G
R
--------
R
Q
L
K
V
D
G
V
R
-----
A
R
-----
T
G
D
L
PRG
G
A
V
W
I
R
P
E
D
S
E
L
V
-------
F
G
P
P
S
G
R
-
R
-
A
Y
L
D
S
L
L
-
S
R
L
-
S
A
R
Y
G
E
Q
L
S
R
Y
E
R
T
V
S
Q
R
N
A
A
L
R
G
G
E
EW
A
M
H
V
W
D
D
V
L
L
K
L
G
T
E
---------------
I
M
-
L
F
R
R
R
A
--
L
T
R
L
D
E
L
A
R
E
A
N
A
Q
L
G
S
R
--
K
T
L
A
-------
L
T
-
L
T
E
S
T
S
-----
P
E
-
T
Y
A
A
D
L
R
G
R
----
R
A
E
E
L
A
R
G
S
T
V
T
G
P
H
R
D
----
D
L
L
L
T
L
G
D
F
P
A
S
-----------
D
Y
A
S
R
G
E
G
--------
R
T
V
A
L
A
L
R
R
A
E
L
E
L
L
R
E
K
----
F
G
E
D
P
V
L
L
L
D
D
F
T
A
E
L
D
P
H
R
R
Q
Y
L
L
D
L
A
A
S
------------
V
-
P
Q
A
I
V
T
G
T
E
L
A
P
--
G
A
A
L
--
T
L
R
A
Q
A
G
R
F
-------------------------
36
HHSearch
82.28
28%
-65
- C4 -
2O5V
1
RECF_DEIRA
A:
[4-346]
----
V
R
L
S
A
L
S
T
L
N
--
Y
R
N
-
L
-
A
P
G
T
L
--
N
F
P
E
G
V
-----
T
G
I
Y
G
-
E
N
G
A
G
K
T
N
L
L
---
E
A
-
A
Y
-----
L
A
L
T
G
Q
T
D
-------
A
P
---
R
I
E
Q
L
I
Q
A
G
E
T
---------------------------------
E
A
Y
V
R
A
D
L
Q
Q
---------------
G
G
S
L
S
I
Q
E
V
G
L
G
R
G
R
--------
R
Q
L
K
V
D
G
V
R
-----
A
-
R
T
G
D
L
-
P
R
G
---
G
A
V
W
I
R
P
E
D
S
E
L
V
-------
F
G
P
P
S
G
R
-
R
-
A
Y
L
D
S
L
L
-
S
R
L
-
S
A
R
Y
G
E
Q
L
S
R
Y
E
R
T
V
S
Q
R
N
A
A
L
R
G
G
--------
E
E
W
A
M
H
V
W
D
D
V
L
L
---------
K
L
G
T
E
-
I
M
L
F
R
R
R
A
L
T
R
L
D
E
L
A
R
E
A
N
A
Q
L
-
G
S
R
-
K
T
L
A
-------
L
T
-
L
T
E
S
T
S
P
E
----------
T
Y
A
A
D
L
R
G
R
R
A
E
E
L
A
R
G
S
T
V
T
G
P
H
R
D
----
D
L
L
L
T
L
G
D
F
P
A
S
-----------
D
Y
A
S
R
G
E
G
--------
R
T
V
A
L
A
L
R
R
A
E
L
E
L
L
R
E
K
----
F
G
E
D
P
V
L
L
L
D
D
F
T
A
E
L
D
P
H
R
R
Q
Y
L
L
D
L
A
A
S
------------
V
-
P
Q
A
I
V
T
G
T
E
L
A
P
--
G
A
---------
A
L
T
L
R
A
Q
A
G
R
F
T
-----------------
57
Fugue
82.08
26%
-58
- C4 -
2O5V
1
RECF_DEIRA
A:
[2-359]
--GD
V
R
L
S
A
L
S
T
L
N
--
Y
R
N
-
L
-
A
P
G
T
L
--
N
F
P
E
G
V
-----
T
G
I
Y
G
-
E
N
G
A
G
K
T
N
L
L
---
E
A
-
A
Y
-----
L
A
L
T
G
Q
T
D
-------
A
P
---
R
I
E
Q
L
I
Q
A
G
E
T
---------------------------------
E
A
Y
V
R
A
D
L
Q
Q
---------------
G
G
S
L
S
I
Q
E
V
G
L
G
R
G
R
--------
R
Q
L
K
V
D
G
V
R
-----
A
R
--
T
G
D
L
P
R
G
---
G
A
V
W
I
R
P
E
D
S
E
L
V
-------
F
G
P
P
S
G
R
-
R
-
A
Y
L
D
S
L
L
-
S
R
L
-
S
A
R
Y
G
E
Q
L
S
R
Y
E
R
T
V
S
Q
R
N
A
A
L
R
--------
G
G
E
E
W
A
M
H
V
W
D
D
V
L
L
---------
K
L
G
T
E
-
I
M
L
F
R
R
R
A
L
T
R
L
D
E
L
A
R
E
A
N
A
Q
L
-
G
-
S
R
K
T
L
A
-------
L
T
-
L
T
E
S
T
S
----------
P
E
T
Y
A
A
D
L
R
G
R
R
A
E
E
L
A
R
G
S
T
V
T
G
P
H
R
D
----
D
L
L
L
T
L
G
D
F
P
A
S
-----------
D
Y
A
S
R
G
E
G
--------
R
T
V
A
L
A
L
R
R
A
E
L
E
L
L
R
E
K
----
F
G
E
D
P
V
L
L
L
D
D
F
T
A
E
L
D
P
H
R
R
Q
Y
L
L
D
L
A
A
S
------------
V
-
P
Q
A
I
V
T
G
T
E
L
A
P
--
G
A
A
L
T
L
R
A
Q
-
A
G
R
F
T
P
V
A
D
E
E
M
Q
A
E
GTA------------
60
Fugue
57.37
18%
-47
- C2 -
1E69
-
?
A:
[1-1164]
----
M
R
L
K
K
L
Y
L
K
G
--
F
K
S
-
F
G
R
P
S
L
I
--
G
F
S
D
R
V
-----
T
A
I
V
G
-
P
N
G
S
G
K
S
N
I
I
---
D
A
-
I
K
-----
W
V
-
F
G
E
K
F
-------
D
M
-
I
-
F
A
G
S
E
N
L
P
P
A
G
---------------------------------
S
A
Y
V
E
L
V
F
E
E
---------------
N
G
E
E
I
T
V
A
R
E
L
K
R
T
G
--------
E
N
T
Y
Y
L
N
G
S
-----
P
V
R
L
K
D
I
R
D
R
F
---
A
G
T
G
L
G
V
D
F
Y
S
I
V
-------
G
--------------------------------------
Q
G
Q
I
D
R
I
V
N
--
A
Y
Q
R
V
N
E
S
F
N
R
F
I
S
L
L
F
F
---------
G
--------------------------------------------
G
E
-
G
R
L
E
I
S
I
R
K
P
G
R
R
-
D
Q
K
L
S
L
L
-----------------------------------------------------
S
G
G
E
K
--------
A
L
V
G
L
A
L
L
F
A
L
M
-----
E
----
I
K
P
S
P
F
Y
V
L
D
E
V
D
S
P
L
D
D
Y
N
A
E
R
F
K
R
L
L
K
E
N
S
----------
K
-
H
T
Q
F
I
V
I
T
H
------
N
K
I
--
V
M
E
-
A
A
D
L
L
H
G
V
T
M
V
N
G
V
S
A
I
V
PVEV--------
62
Fugue
50.33
20%
-41
- C1 -
3DSM
1
?
A:
[1-327]
------
A
S
G
L
F
I
T
N
EG
N
F
Q
-
Y
-
S
N
A
T
L
S
-
Y
Y
D
P
A
T
C
E
V
E
N
E
V
F
Y
R
-
A
N
G
F
K
L
G
D
V
A
---
Q
S
M
V
I
R
DG
I
G
W
I
V
V
N
N
S
H
---------------
V
I
F
A
I
D
I
N
---------------------------------
T
F
K
E
V
G
R
I
T
-----------------
G
F
T
S
P
R
Y
I
H
F
L
S
D
---------
E
K
A
Y
V
T
Q
--------------
I
W
D
Y
---
R
I
F
I
I
N
P
K
T
Y
E
I
T
-------
G
Y
I
E
C
P
D
M
D
M
E
S
G
S
T
E
Q
M
V
Q
Y
G
K
Y
V
Y
V
N
C
W
S
Y
Q
N
R
I
L
K
I
D
T
E
T
D
K
V
V
D
--
E
L
T
------
I
G
I
Q
P
T
S
L
V
M
--------
D
K
Y
N
K
M
W
T
I
T
D
G
G
Y
E
G
S
P
Y
G
Y
E
A
P
S
L
Y
R
I
-
D
--
A
E
T
F
T
-------
V
E
-
K
Q
F
K
F
K
L
-
G
D
W
P
S
---------------------
E
V
Q
L
N
G
T
R
------
D
T
L
Y
W
I
N
N
D
I
W
R
M
----------
P
V
E
A
D
R
V
P
--------
V
R
P
F
L
E
F
R
D
T
K
Y
Y
G
L
T
V
N
----
P
N
N
G
E
V
Y
V
A
D
----------------
A
I
D
Y
------------
Q
-
Q
Q
G
I
V
Y
R
Y
S
P
Q
G
KL
I
D
E
F
--
Y
V
G
-
I
I
P
G
A
F
C
W
K
L
E
H
H
H
H
H--------------
43
HHSearch
50.12
24%
-36
- C4 -
1F2T
-
RAD50_PYRFU
A:
[1-88]
----
M
K
L
E
R
V
T
V
K
N
--
F
R
S
-
H
-
S
D
T
V
V
--
E
F
K
E
G
I
-----
N
L
I
I
G
-
Q
N
G
S
G
K
S
S
L
L
---
D
A
-
I
L
-----
V
G
L
Y
W
P
L
R
-------
I
K
-
D
I
K
K
D
E
F
T
K
V
G
A
R
---------------------------------
D
T
Y
I
D
L
I
F
E
K
---------------
D
G
T
K
Y
R
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
50.05
37%
-21
- C4 -
4NCH
1
?
B:
[1-80]
----
M
K
L
E
R
V
T
V
K
N
--
F
R
S
-
H
-
S
D
T
V
V
--
E
F
K
E
G
I
-----
N
L
I
I
G
-
Q
N
G
S
G
K
S
S
L
L
---
D
A
-
I
L
-----
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
58
Fugue
49.31
11%
-19
- C2 -
3EUJ
2
MUKB_HAEDU
A:
[3-483]
M
I
A
R
G
K
F
R
S
L
T
L
I
N
--
W
N
G
-
F
-
F
A
R
T
F
--
D
F
D
E
L
V
-----
T
T
L
S
G
-
G
N
G
A
G
K
S
T
T
M
---
A
G
-
F
V
-----
T
A
L
I
P
D
L
T
-------
L
L
-
N
-
F
R
N
T
T
E
A
G
S
T
S
---------------------------------
S
S
R
D
K
G
L
Y
G
K
LKA
G
V
C
Y
A
V
L
E
T
V
N
S
R
A
Q
R
I
I
T
G
V
R
L
Q
Q
I
A
GRDK
K
V
D
I
R
P
F
S
L
Q
N
V
P
MTDS
V
I
S
L
F
T
E
Q
V
A
N
K
---
A
R
V
L
S
L
N
D
L
K
E
K
F
E
ETA
V
T
F
K
P
Y
H
S
I
T
-
D
-
Y
H
S
F
M
F
D
-
L
G
I
-
L
P
K
R
L
R
S
S
S
D
R
N
K
F
Y
K
L
I
E
A
S
L
Y
G
G
I
--
S
S
V
I
T
K
S
--
L
R
D
Y
L
L
P
E
N
---------
S
G
V
R
Q
-
A
F
Q
D
A
E
S
V
A
N
I
L
R
K
T
I
Q
R
E
Q
N
R
I
-
L
Q
L
N
Q
G
L
Q
NIAFGQV
K
G
-
V
R
L
V
V
N
I
R
D
T
H
S
I
-
L
L
N
A
L
S
D
Q
S
F
S
E
A
L
A
M
L
Y
K
R
I
G
E
E
L
L
D
Y
R
N
----
Y
L
D
L
E
V
E
T
L
R
G
A
YGWMRAESSAL
S
T
G
E
A
I
G
T
--------
G
M
S
I
L
L
M
V
V
Q
S
W
E
E
E
S
R
R
MRAK
D
I
L
P
C
R
L
L
F
L
D
Q
A
A
R
L
D
A
M
S
I
N
T
L
F
E
L
C
E
R
------------
L
D
M
Q
L
L
I
A
A
P
E
N
----
I
S
P
E
--
R
G
T
-
T
Y
K
L
V
R
K
I
L
A
N
Q
E
Y
V
H
V
V
G
L
K
GFG------
4
PsiBlast_PDB
48.79
37%
-22
- C4 -
1F2T
-
RAD50_PYRFU
A:
[1-49]
----
M
K
L
E
R
V
T
V
K
N
--
F
R
S
-
H
-
S
D
T
V
V
--
E
F
K
E
G
I
-----
N
L
I
I
G
-
Q
N
G
S
G
K
S
S
L
L
---
D
A
-
I
L
-----
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
PsiBlast_CBE
48.26
31%
-21
- C4 -
3QF7
2
RAD50_THEMA
B:
[1-70]
----
M
R
P
E
R
L
T
V
R
N
--
F
L
G
-
L
-
K
N
V
D
I
--
E
F
Q
S
G
I
-----
T
V
V
E
G
-
P
N
G
A
G
K
S
S
L
F
---
E
A
-
I
S
-----
F
A
L
F
G
N
G
I
-------
R
Y
-
P
-
N
S
Y
D
Y
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
48.04
31%
-15
- C4 -
4W9M
2
?
C:
[1-73]
----
M
R
P
E
R
L
T
V
R
N
--
F
L
G
-
L
-
K
N
V
D
I
--
E
F
Q
S
G
I
-----
T
V
V
E
G
-
P
N
G
A
G
K
S
S
L
F
---
E
A
-
I
S
-----
F
A
L
F
G
N
G
I
-------
R
Y
-
P
-
N
S
Y
D
Y
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
47.84
33%
-22
- C4 -
3AUX
2
RAD50_METJA
A:
[3-70]
----
M
I
L
K
E
I
R
M
N
N
--
F
K
S
-
H
-
V
N
S
R
I
--
K
F
E
K
G
I
-----
V
A
I
I
G
-
E
N
G
S
G
K
S
S
I
F
---
E
A
-
V
F
-----
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
45
HHSearch
47.77
24%
-41
- C4 -
3QKS
-
RAD50_PYRFU
A:
[1-84]
----
M
K
L
E
R
V
T
V
K
N
--
F
R
S
-
H
-
S
D
T
V
V
--
E
F
K
E
G
I
-----
N
L
I
I
G
-
Q
N
G
S
G
K
S
S
L
L
---
D
A
-
I
L
-----
V
G
L
Y
W
P
L
R
-------
I
K
D
I
-
K
K
D
E
F
T
K
V
G
A
R
---------------------------------
D
T
Y
I
D
L
I
F
E
K
---------------
D
G
T
K
Y
R
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
PsiBlast_CBE
47.59
31%
-19
- C4 -
4W9M
2
?
E:
[1-74]
----
M
R
P
E
R
L
T
V
R
N
--
F
L
G
-
L
-
K
N
V
D
I
--
E
F
Q
S
G
I
-----
T
V
V
E
G
-
P
N
G
A
G
K
S
S
L
F
---
E
A
-
I
S
-----
F
A
L
F
G
N
G
I
-------
R
Y
-
P
-
N
S
Y
D
Y
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
66
Fugue
47.35
18%
16
- C3 -
4O6D
8
?
A:
[19-377]
----
L
Y
F
Q
S
N
A
D
T
G
--
C
A
I
D
I
-
S
R
Q
E
L
--
R
C
G
S
G
V
-----
F
I
H
N
D
V
E
A
W
M
D
R
Y
K
Y
Y
P
ET
P
Q
-
G
L
-----
A
K
I
I
Q
K
A
H
K
E
GVC
G
L
R
S
-
V
-
S
R
L
E
H
Q
M
W
E
A
V
---------------------------------
K
D
E
L
N
T
L
L
K
E
---------------
N
G
V
D
L
S
V
V
V
E
-
K
Q
E
G
--------
M
Y
K
S
A
P
---------
K
R
L
T
A
-
T
A
N
N
---
T
F
V
V
D
G
P
E
T
-----------
K
E
C
P
T
Q
N
-
R
-
A
W
N
S
L
E
V
-
E
D
F
-
G
----
F
G
L
T
S
T
R
M
F
L
K
V
R
E
S
---------------------------------------
N
-
T
T
E
C
D
S
K
I
I
G
T
A
V
K
N
N
L
A
I
H
S
D
L
-
S
Y
W
I
E
S
R
L
-------
N
D
T
W
K
L
E
R
A
V
L
G
E
V
K
S
C
T
W
P
E
T
H
T
L
W
G
D
G
I
L
E
S
D
L
I
I
P
V
T
L
A
G
P
R
------
S
N
H
N
R
R
P
G
Y
K
T
Q
-----------
N
Q
G
P
W
D
E
G
--------
R
--------
V
E
I
D
F
D
Y
C
P
----
G
T
T
V
T
L
-------
S
E
S
C
G
H
R
G
P
A
T
R
T
T
T
E
S
G
K
L
I
T
D
WCCR
S
C
T
-
L
P
P
L
R
Y
Q
T
D
S
G
C
--
W
Y
G
M
--
E
I
R
-
P
Q
R
H
---
D
E
K
T
L
V
Q
S
QVNA-----------
30
PsiBlast_CBE
47.35
37%
-17
- C4 -
4NCJ
3
?
B:
[1-73]
----
M
K
L
E
R
V
T
V
K
N
--
F
R
S
-
H
-
S
D
T
V
V
--
E
F
K
E
G
I
-----
N
L
I
I
G
-
Q
N
G
S
G
K
S
S
L
L
---
D
A
-
I
L
-----
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
PsiBlast_CBE
47.31
37%
-22
- C4 -
4NCJ
3
?
C:
[1-64]
----
M
K
L
E
R
V
T
V
K
N
--
F
R
S
-
H
-
S
D
T
V
V
--
E
F
K
E
G
I
-----
N
L
I
I
G
-
Q
N
G
S
G
K
S
S
L
L
---
D
A
-
I
L
-----
V
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
61
Fugue
47.05
14%
-22
- C2 -
4UX3
2
SMC3_YEAST
A:
[3-527]
-----
Y
I
K
R
V
I
I
K
G
--
F
K
T
-
Y
-
R
N
E
T
I
I
D
N
F
S
P
H
Q
-----
N
V
I
I
G
-
S
N
G
S
G
K
S
N
F
F
---
A
A
-
I
R
-----
F
V
L
S
D
D
Y
S
-------
N
L
-
K
-
R
E
E
R
Q
G
L
I
H
Q
G
SGGSVM
S
A
S
V
E
I
VI
R
R
T
V
G
LKKDDYQLNDRNVT
K
G
D
I
V
R
M
L
E
T
---------------
A
G
F
S
M
N
N
P
Y
N
I
V
P
Q
G
--------
K
I
V
A
L
T
N
A
K
-----
D
K
E
R
L
Q
L
L
E
D
V
V
--
G
A
K
S
F
E
V
K
L
K
A
S
L
-------
K
K
M
E
E
T
E
-
Q
-
K
K
I
Q
I
N
---
K
E
-
M
G
E
L
N
S
K
L
S
E
M
E
Q
E
R
K
E
L
E
K
Y
N
E
L
E
R
--
N
R
K
I
Y
Q
F
T
L
Y
D
R
E
L
N
E
V
I
N
QMETSDQL
L
Q
R
L
N
-
D
M
N
T
E
I
S
G
L
K
N
V
N
K
R
A
F
E
N
F
K
K
F
-
N
E
R
R
K
D
L
A
-------
E
R
-
A
S
E
L
D
E
S
K
D
S
I
Q
D
-
L
I
V
K
L
K
Q
Q
K
V
N
A
V
D
S
T
F
Q
K
V
S
E
N
F
E
A
V
F
E
R
L
V
PR
G
T
A
K
L
I
I
H
S
I
S
V
-----------
S
F
N
S
K
Q
N
E
QLHVEQLS
G
G
Q
K
T
V
C
A
I
A
L
I
L
A
I
Q
M
V
----
D
-
P
A
S
F
Y
L
F
D
E
I
D
A
A
L
D
K
Q
Y
R
T
A
V
A
T
L
L
K
E
------------
L
-
S
K
N
A
Q
F
I
C
T
T
----
F
R
T
D
--
M
L
Q
-
V
A
D
K
F
F
R
V
K
Y
E
N
K
I
S
T
V
I
E
V
N
R
E
E
A
I
G
F
I
R
16
PsiBlast_PDB
47.02
33%
-19
- C4 -
3AUY
2
RAD50_METJA
A:
[3-52]
----
M
I
L
K
E
I
R
M
N
N
--
F
K
S
-
H
-
V
N
S
R
I
--
K
F
E
K
G
I
-----
V
A
I
I
G
-
E
N
G
S
G
K
S
S
I
F
---
E
A
-
V
F
-----
F
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
PsiBlast_CBE
46.86
31%
-15
- C4 -
4W9M
2
?
I:
[1-73]
----
M
R
P
E
R
L
T
V
R
N
--
F
L
G
-
L
-
K
N
V
D
I
--
E
F
Q
S
G
I
-----
T
V
V
E
G
-
P
N
G
A
G
K
S
S
L
F
---
E
A
-
I
S
-----
F
A
L
F
G
N
G
I
-------
R
Y
-
P
-
N
S
Y
D
Y
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------