@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0012: (2016-03-11 )
LYQMKNKLQVKIPGKLYVAGEYAVVESGHTAILTAVNRYITLTLEDSERNELWIPHYENPVSWPVGGELKPDGEHWTFTAEAINIATTFLKSEGIELTPVKMIIETELIDQSGAKYGLGSSAAATVAVINALMTKFYPEISMLKKFKLAALSHLVVQGNGSCGDIASCMYGGWIAYTTFDQEWVKHRLAYKSLEWFMKEPWPMLQIETLEEPVPTFSVGWTGTPVSTGKLVSQIHAFKQEDSKNYQHFLTRNNEIMKQIIQAFHTKDEELLYSAIKENRRILQELGTKAGVNIETSLLKELADSAENMGGAGKSSGSGGGDCGIAFSKTKELAEKLVNEWEKLGIKHLPFHTGRVQITE
Atome Classification :
(20 SA)
-------------.......-..10........20.....-----...30......--.-.-.40.........50.....----....60--.--..---------..---.--..--70--.-..-......80...-----------.....90........100....------------...----110.......120.......130..---------------....---------------.140.......150...---...-.160..-......170-----.......180.......190....----------...200.......210-.--.-.----....220.-....------------..-230..-------.....------240-----------.......---------..250-.----.--.......260-------.......270.......280...--...---.290........300.....-..-310--.-.......320....---.---..330.---......340.......350..--.....-------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------LYQMK
N
K
-
L
Q
V
KIP
G
K
L
Y
V
A
G
E
Y
A
V
VE-----SG
H
T
-
A
I
L
T
AV--N-
R
-
Y
I
-
T
L
T
LEDSERN-
E
L
WIP----HYENPV--S--WP---------VG---G--EL--K---P-DG-E
H
W
T
F
T
A
E
A
I
N
-----------
I
A
T
T
F
L
KSEG
I
E
LT
P
V
K
M
I
I
E
T
------------
E
LI----DQSGAKYGLGS
S
A
A
A
T
V
A
V
I
N
A
L
M
T
---------------
K
FY
P
---------------
E
I
S
M
L
K
K
F
K
L
A
A
L
S
H
L
V
---
V
QG-NG-S
C
G
-
D
I
A
S
C
M
YG
G
-----
W
I
A
Y
T
TF
D
Q
E
W
V
K
H
R
L
A
Y
K
S
L
E
W
F
----------
M
KEPW
P
M
L
Q
I
E
TLEEP-V--P-
T
----
F
SVGWTGT-PV
S
T
------------
G
K
-
L
V
S
Q
I
-------
H
A
F
K
Q------E-------------DSK
N
Y
Q
H
---------
F
L
T---R----
N
--
N
E
I
M
K
Q
I
I
Q
A
-------FHTK
D
E
E
L
L
Y
S
A
I
K
E
N
R
R
I
L
Q
E
L--GTK---AGV-N
I
E
T
S
L
L
K
E
L
A
D
S
A
E
N-MG-G-A--G-KSSGSGGGDCGIA
F
---
S
---
K
T
K
E
L
A
---
E
K
L
V
N
E
W
E
KLGIKHLPFHT
G
R
--
V
Q
ITE-------------
1
PsiBlast_PDB
99.37
96%
-105
- C1 -
3K17
1
?
A:
[5-358]
------------------
N
K
-
L
Q
V
K
I
P
G
K
L
Y
V
A
G
E
Y
A
V
V
E
-----
S
G
H
T
-
A
I
L
T
A
V
--
N
-
R
-
Y
I
-
T
L
T
L
E
D
S
E
R
N
-
E
L
W
I
P
----
H
Y
E
N
P
V
--
S
--
W
P
---------
I
G
---
G
--
E
L
--
K
---
P
-
D
G
-
E
H
W
T
F
T
A
E
A
I
N
-----------
I
A
T
T
F
L
K
S
E
G
I
E
L
T
P
V
K
M
V
I
E
T
------------
E
L
I
----
D
Q
S
G
A
K
Y
G
L
G
S
S
A
A
A
T
V
A
V
I
N
A
L
M
T
---------------
K
F
Y
P
---------------
E
I
S
M
L
K
K
F
K
L
A
A
L
S
H
L
V
---
V
Q
G
-
N
G
-
S
C
G
-
D
I
A
S
C
M
Y
G
G
-----
W
I
A
Y
T
T
F
D
Q
E
W
V
K
H
R
L
A
Y
K
S
L
E
W
F
----------
M
K
E
P
W
P
M
L
Q
I
E
T
L
E
E
P
-
V
--
P
-
T
----
F
S
V
G
W
T
G
T
-
P
V
S
T
------------
G
K
-
L
V
S
Q
I
-------
H
A
F
K
Q
------
E
-------------
D
S
K
N
Y
Q
H
---------
F
L
T
---
R
----
N
--
N
E
I
M
K
Q
I
I
Q
A
-------
F
H
T
K
D
E
E
L
L
Y
S
S
I
K
E
N
R
R
I
L
Q
E
L
--
G
T
K
---
A
G
V
-
N
I
E
T
S
L
L
K
E
L
A
D
S
A
E
N
-
M
G
-
G
-
A
--
G
-
K
S
S
G
S
G
G
G
D
C
G
I
A
F
---
S
---
K
T
K
E
L
A
---
E
K
L
V
N
E
W
E
K
L
G
I
K
H
L
P
F
H
T
G
R
--
V
Q
I
T
E
-------------
21
HHSearch
97.65
93%
-109
- C1 -
3K17
1
?
A:
[5-358]
------------------
N
K
-
L
Q
V
K
I
P
G
K
L
Y
V
A
G
E
Y
A
V
V
E
------
S
G
H
T
A
I
L
T
A
V
--
N
-
R
-
Y
I
-
T
L
T
L
E
D
S
E
---
R
N
E
L
W
----
I
P
H
Y
E
N
--
P
V
S
W
P
---------
I
G
---
G
--
E
L
--
K
---
P
-
D
G
-
E
H
W
T
F
T
A
E
A
I
N
-----------
I
A
T
T
F
L
K
S
E
G
I
E
L
T
P
V
K
M
V
I
E
T
------------
E
L
I
DQSG
A
----
K
Y
G
L
G
S
S
A
A
A
T
V
A
V
I
N
A
L
M
T
---------------
K
F
Y
P
---------------
E
I
S
M
L
K
K
F
K
L
A
A
L
S
H
L
V
---
V
Q
G
-
N
G
-
S
C
G
-
D
I
A
S
C
M
Y
G
G
-----
W
I
A
Y
T
T
F
D
Q
E
W
V
K
H
R
L
A
Y
K
S
L
E
W
F
----------
M
K
E
P
W
P
M
L
Q
I
E
T
L
E
E
--
P
--
V
P
T
----
F
S
V
G
W
T
G
T
-
P
V
S
T
------------
G
K
-
L
V
S
Q
I
-------
H
A
F
K
Q
------
E
-------------
D
S
K
N
Y
Q
H
---------
F
L
T
---
R
----
N
--
N
E
I
M
K
Q
I
I
Q
A
-------
F
H
T
K
D
E
E
L
L
Y
S
S
I
K
E
N
R
R
I
L
Q
E
L
--
G
T
K
---
A
G
V
-
N
I
E
T
S
L
L
K
E
L
A
D
S
A
E
N
-
M
G
-
G
-
A
--
G
-
K
S
S
G
S
G
G
G
D
C
G
I
A
F
---
S
---
K
T
K
E
L
A
---
E
K
L
V
N
E
W
E
K
L
G
I
K
H
L
P
F
H
T
G
R
--
V
Q
I
T
E
-------------
2
PsiBlast_PDB
71.01
29%
-84
- C1 -
3GON
3
?
A:
[2-324]
---------------------
I
A
V
K
T
C
G
K
L
Y
W
A
G
E
Y
A
I
L
E
-----
P
G
Q
L
-
A
L
I
K
D
I
--
P
-
I
-
Y
M
-
R
A
E
I
A
F
S
D
S
Y
-
R
I
Y
S
D
----
M
F
D
F
A
V
------------------------
D
L
--
R
---
P
-
N
P
-
D
Y
-
S
L
I
Q
E
T
I
A
-----------
L
M
G
D
F
L
A
V
R
G
Q
N
L
R
P
F
S
L
A
I
Y
G
------------
K
M
-----
E
R
E
G
K
K
F
G
L
G
S
S
G
S
V
V
V
L
V
V
K
A
L
L
A
---------------
L
Y
N
L
---------------
S
V
D
Q
N
L
L
F
K
L
T
S
A
V
L
L
K
---
R
G
D
-
N
G
-
S
M
G
-
D
L
A
C
I
A
A
E
D
-----
L
V
L
Y
Q
S
F
D
R
Q
K
V
A
A
W
L
E
E
E
N
L
A
T
V
----------
L
E
R
D
W
G
F
----
S
I
S
Q
V
-
K
--
P
-
T
L
E
C
D
F
L
V
G
W
T
K
E
-
V
A
V
S
------------
S
H
-
M
V
Q
Q
I
----------
K
Q
------
N
-------------
I
N
Q
N
------------
F
L
T
---
S
----
S
--
K
E
T
V
V
S
L
V
E
A
-------
L
E
Q
G
K
S
E
K
I
I
E
Q
V
E
V
A
S
K
L
L
E
G
L
--
S
T
--------
D
I
Y
T
P
L
L
R
Q
L
K
E
A
S
Q
D
-
L
Q
-
A
-
V
--
A
-
K
S
S
G
A
G
G
G
D
C
G
I
A
L
---
S
---
F
D
A
Q
S
T
---
K
T
L
K
N
R
W
A
D
L
G
I
E
L
L
--------------------------
22
HHSearch
68.03
29%
-89
- C1 -
3GON
3
?
A:
[1-328]
-------------------
M
-
I
A
V
K
T
C
G
K
L
Y
W
A
G
E
Y
A
I
L
E
------
P
G
Q
L
A
L
I
K
D
I
--
P
-
I
-
Y
M
-
R
A
E
I
A
F
S
D
S
Y
-
R
--
I
Y
----
S
D
M
F
D
F
--
A
--
V
-------------------
D
--
L
---
R
-
P
N
-
P
D
Y
S
L
I
Q
E
T
I
A
-----------
L
M
G
D
F
L
A
V
R
G
Q
N
L
R
P
F
S
L
A
I
Y
G
------------
K
M
E
----
R
-
E
G
K
K
F
G
L
G
S
S
G
S
V
V
V
L
V
V
K
A
L
L
A
---------------
L
Y
N
L
---------------
S
V
D
Q
N
L
L
F
K
L
T
S
A
V
L
L
K
---
R
G
D
-
N
G
-
S
M
G
-
D
L
A
C
I
A
A
E
D
-----
L
V
L
Y
Q
S
F
D
R
Q
K
V
A
A
W
L
E
E
E
N
L
A
T
V
----------
L
E
R
D
W
G
F
-
S
I
S
Q
V
K
P
T
-
L
--
E
C
D
----
F
L
V
G
W
T
K
E
-
V
A
V
S
------------
S
H
-
M
V
Q
Q
I
-------
K
Q
N
I
N
-------------------------
Q
N
---------
F
L
T
---
S
----
S
--
K
E
T
V
V
S
L
V
E
A
-------
L
E
Q
G
K
S
E
K
I
I
E
Q
V
E
V
A
S
K
L
L
E
G
L
--
S
T
--------
D
I
Y
T
P
L
L
R
Q
L
K
E
A
S
Q
D
-
L
Q
-
A
-
V
--
A
-
K
S
S
G
A
G
G
G
D
C
G
I
A
L
---
S
---
F
D
A
Q
S
T
---
K
T
L
K
N
R
W
A
D
L
G
I
E
L
L
Y
Q
E
R
----------------------
24
HHSearch
61.47
23%
-71
- C1 -
1KVK
2
KIME_RAT
A:
[1-374]
---------------
M
L
S
E
V
-
L
L
V
S
A
P
G
K
V
I
L
H
G
E
H
A
V
V
H
------
G
K
V
-
A
L
A
V
A
L
--
N
-
L
-
R
T
-
F
L
V
L
R
P
Q
S
N
G
-
K
V
S
L
N
----
L
P
N
V
G
I
K
Q
V
--
W
D
V
A
T
L
Q
L
LDT------------
E
---
K
-
L
K
-
K
V
A
G
L
P
R
D
C
V
G
NE
G
L
S
L
L
A
F
L
Y
L
Y
L
A
I
C
R
K
Q
-
R
T
L
P
S
L
D
I
M
V
W
S
------------
E
L
P
----
P
----
G
A
G
L
G
S
S
A
A
Y
S
V
C
V
A
A
A
L
L
T
---------------
A
C
E
E
VTNPLKDRGS
I
G
S
W
P
E
E
D
L
K
S
I
N
K
W
A
Y
E
G
E
R
V
---
I
H
G
-
N
P
-
S
G
V
-
D
N
S
V
S
T
W
G
G
-----
A
L
R
Y
Q
Q
G
K
M
-----------------------------------
S
S
L
K
R
L
-
P
--
A
L
Q
----
I
L
L
T
N
T
K
V
-
P
R
S
T
------------
K
A
-
L
V
A
G
V
-------
R
S
R
L
I
------
K
-------------
F
P
E
I
M
A
P
---------
L
L
T
---
S
----
I
--
D
A
I
S
L
E
C
E
R
V
L
G
E
M
A
A
A
P
V
P
E
Q
Y
L
V
L
E
E
L
M
D
M
N
Q
H
H
L
N
A
L
--
G
V
----------
G
H
A
S
L
D
Q
L
C
Q
V
T
A
A
-
H
G
-
L
-
H
--
S
-
K
L
T
G
A
G
G
G
G
C
G
I
T
L
---
L
---
K
P
G
L
E
R
A
K
V
E
A
A
K
Q
A
L
T
G
C
G
F
D
C
W
E
T
S
I
G
A
--------------------
27
HHSearch
60.90
22%
-78
* C1 *
1KKH
2
MVK_METJA
A:
[1-315]
---------------
P
R
G
S
H
-
M
I
I
E
T
P
S
K
V
I
L
F
G
E
H
A
V
V
Y
------
G
Y
R
-
A
I
S
M
A
I
--
D
-
L
-
T
S
-
T
I
E
I
K
E
T
Q
E
D
-
E
I
I
L
N
----
L
N
D
L
N
K
--
S
L
G
L
N
---------
L
N
---
E
IK
N
I
--
N
---
P
N
N
F
-
G
D
F
K
Y
C
L
C
A
I
K
-----------
N
T
L
D
Y
L
N
I
--
E
P
K
T
G
F
K
I
N
I
S
S
------------
K
I
P
----
I
----
S
C
G
L
G
S
S
A
S
I
T
I
G
T
I
K
A
V
S
G
---------------
F
Y
N
K
---------------
E
L
K
D
D
E
I
A
K
L
G
Y
M
V
E
K
E
---
I
Q
G
-
K
A
-
S
I
T
-
D
T
S
T
I
T
Y
K
G
-----
I
L
E
I
K
N
N
K
F
R
K
------------------------------
I
K
G
E
F
E
E
F
L
-
K
--
N
C
K
----
F
L
I
V
Y
A
E
K
R
K
K
K
T
------------
A
E
-
L
V
N
E
V
-------
A
K
I
E
N
------------------------
K
D
E
---------
I
F
------------
K
E
I
D
K
V
I
D
E
A
-------
L
K
I
K
N
K
E
D
F
G
K
L
M
T
K
N
H
E
L
L
K
K
L
--
N
I
----------
S
T
P
K
L
D
R
I
V
D
I
G
N
R
-
F
G
-
F
-
G
--
A
-
K
L
T
G
A
G
G
G
G
C
V
I
I
L
---
V
---
N
E
E
K
-
E
---
K
E
L
L
K
E
L
N
K
E
D
V
R
I
F
N
C
R
M
----------------------
4
PsiBlast_PDB
60.01
24%
-88
- C1 -
1KKH
2
MVK_METJA
A:
[8-288]
-----------------------
I
E
T
P
S
K
V
I
L
F
G
E
H
A
V
V
------
Y
G
Y
R
-
A
I
S
M
A
I
--
D
-
L
-
T
S
-
T
I
E
I
K
E
T
Q
E
D
-
E
I
I
L
N
----
L
--
N
D
L
--
N
--
K
S
---------
L
G
L
N
L
N
--
E
I
--
K
NIN
P
-
N
N
F
G
D
F
K
Y
C
L
C
A
I
K
-----------
N
T
L
D
Y
L
N
I
E
--
P
K
T
G
F
K
I
N
I
S
S
------------
K
I
--------
P
I
S
C
G
L
G
S
S
A
S
I
T
I
G
T
I
K
A
V
-
S
---------------
G
F
Y
N
---------------
K
--
E
L
K
D
D
E
I
A
K
L
G
Y
M
V
E
K
E
I
Q
G
-
K
A
-
S
I
T
-
D
T
S
T
I
T
Y
K
G
-----
I
L
E
I
K
N
-----
N
K
F
R
K
I
K
G
E
F
E
E
F
----------
L
K
N
C
K
F
L
I
---------------------
V
Y
A
E
K
R
-
K
K
K
T
------------
A
E
-
L
V
N
E
V
-------
A
K
I
E
N
------
K
-------------
D
----
E
I
---------
F
-------------
K
E
I
D
K
V
I
D
E
A
-------
L
K
I
K
N
K
E
D
F
G
K
L
M
T
K
N
H
E
L
L
K
K
L
------------
N
I
S
T
P
K
L
D
R
I
V
D
I
G
N
R
-
F
G
-
F
-
G
--
A
-
K
L
T
G
A
G
G
G
G
C
V
I
-----------------------------------------------------------
3
PsiBlast_PDB
59.67
25%
-81
- C1 -
1VIS
1
MVK_METJA
A:
[3-285]
---------------------
L
I
I
E
T
P
S
K
V
I
L
F
G
E
H
A
V
V
------
Y
G
Y
R
-
A
I
S
M
A
I
--
D
-
L
-
T
S
-
T
I
E
I
K
E
T
Q
E
D
-
E
I
I
L
N
----
L
--
N
D
L
--
N
--
K
S
---------
L
G
L
N
L
N
--
E
I
--
K
NIN
P
-
N
N
F
G
D
F
K
Y
C
L
C
A
I
K
-----------
N
T
L
D
Y
L
N
I
E
--
P
K
T
G
F
K
I
N
I
S
S
------------
K
I
--------
P
I
S
C
G
L
G
S
S
A
S
I
T
I
G
T
I
K
A
V
-
S
---------------
G
F
Y
N
---------------
K
--
E
L
K
D
D
E
I
A
K
L
G
Y
M
V
E
K
E
I
Q
G
-
K
A
-
S
I
T
-
D
T
S
T
I
T
Y
K
G
-----
I
L
E
I
K
N
-----
N
K
F
R
K
I
K
G
E
F
E
E
F
----------
L
K
N
C
K
F
L
I
---------------------
V
Y
A
E
K
R
-
K
K
K
T
------------
A
E
-
L
V
N
E
V
-------
A
K
I
E
N
------
K
-------------
D
----
E
I
---------
F
-------------
K
E
I
D
K
V
I
D
E
A
-------
L
K
I
K
N
K
E
D
F
G
K
L
M
T
K
N
H
E
L
L
K
K
L
------------
N
I
S
T
P
K
L
D
R
I
V
D
I
G
N
R
-
F
G
-
F
-
G
--
A
-
K
L
T
G
A
G
G
G
G
C
V
I
-----------------------------------------------------------
7
PsiBlast_PDB
59.64
26%
-57
- C1 -
4HAC
1
?
A:
[27-310]
--------------------------
P
G
K
I
Y
L
F
G
E
H
A
V
V
Y
------
G
E
T
-
A
I
A
C
A
V
E
L
R
-
T
-
R
V
-
R
A
E
L
N
D
S
I
T
I
-
Q
S
Q
I
--------------------------------
G
--
R
T
--
G
---
L
-
D
F
-
E
K
H
P
Y
V
S
A
V
I
E
-----------
K
M
R
K
S
I
P
I
N
G
V
F
L
T
-----
V
D
S
------------
D
I
P
----
V
G
S
G
----
L
G
S
S
A
A
V
T
I
A
S
I
G
A
L
N
E
---------------
L
F
G
F
---------------
G
L
S
L
Q
E
I
A
K
L
G
H
E
I
E
I
K
---
V
Q
G
-
A
A
-
S
P
T
-
D
T
Y
V
S
T
F
G
G
-----
V
V
--------
T
I
P
E
R
-----------------------------
R
K
L
K
T
P
-
D
--
C
-
G
----
I
V
I
G
D
T
G
V
-
F
S
S
T
------------
K
E
-
L
V
A
N
V
-------
R
Q
L
R
E
------
S
-------------
Y
P
D
L
I
E
P
---------
L
M
T
---
S
----
I
--
G
K
I
S
R
I
G
E
Q
L
-------
V
L
S
G
D
----
Y
A
S
I
G
R
L
M
N
V
N
Q
G
L
--
L
D
A
---
L
G
V
-
N
I
L
E
--
L
S
Q
L
I
Y
S
A
R
A
-
A
G
-
A
-
F
--
G
A
K
I
T
G
A
G
G
G
G
C
M
V
A
L
---
T
A
PE
K
C
N
Q
V
A
---
E
A
V
A
G
A
G
G
K
V
T
I
-----------------------------
45
Fugue
57.66
20%
-63
- C1 -
1KVK
2
KIME_RAT
A:
[1-394]
---------------
M
L
S
E
V
-
L
L
V
S
A
P
G
K
V
I
L
H
G
E
H
A
V
V
H
------
G
K
V
-
A
L
A
V
A
L
--
N
-
L
-
R
T
-
F
L
V
L
R
P
Q
S
N
G
-
K
V
S
L
N
----
L
P
N
V
G
I
--
K
--
Q
V
---------
W
D
---
V
--
A
T
--
L
---
Q
-
L
L
-
D
T
E
K
L
K
K
V
A
G
L
-----------
P
R
D
C
V
G
N
E
G
L
S
L
L
A
F
L
Y
L
Y
L
A
I
CRKQR
T
L
P
S
L
D
I
M
V
W
----
S
E
L
P
P
G
A
G
L
G
S
S
A
A
Y
S
V
C
V
A
A
A
L
L
T
A
C
EEVTNPLKDRGS
I
G
S
W
P
---------------
E
E
D
L
K
S
I
N
K
W
A
Y
E
G
E
R
V
---
I
H
G
-
N
P
-
S
G
V
-
D
N
S
V
S
T
W
G
G
-----
A
L
R
Y
Q
Q
G
K
M
S
S
L
K
----------------------------------
R
L
P
-
A
--
L
-
Q
----
I
L
L
T
N
T
K
V
-
P
R
S
T
------------
K
A
-
L
V
A
G
V
-------
R
S
R
L
I
------
K
-------------
F
P
E
I
M
A
P
---------
L
L
T
---
S
----
I
--
D
A
I
S
L
E
C
E
R
V
-------
L
G
E
M
A
A
A
P
V
P
E
Q
Y
L
V
L
E
E
L
M
D
M
N
--
Q
H
H
---
L
N
A
L
G
V
G
H
A
S
L
D
Q
L
C
Q
V
T
A
A
-
H
G
-
L
-
H
--
S
-
K
L
T
G
A
G
G
G
G
C
G
I
T
L
L
K
P
G
---
L
E
R
A
K
V
---
E
A
A
K
Q
A
L
T
G
C
G
F
D
C
W
E
T
S
I
G
A
P
G
V
S
M
H
S
ATSIE
D
P
V
R
Q
A
L
G
29
HHSearch
56.73
22%
-78
- C1 -
2OI2
2
?
A:
[4-288]
------------------
K
V
-
G
V
G
Q
A
H
S
K
I
I
L
I
G
E
H
A
V
V
Y
------
G
Y
P
-
A
I
S
L
P
L
--
L
-
E
V
E
V
-
T
C
K
V
V
P
A
E
-
S
-
P
W
R
L
Y
------------------------------------------
E
-
E
D
-
T
L
S
M
A
V
Y
A
S
L
---------------
E
Y
L
---
N
I
T
E
A
C
I
R
C
E
I
D
--------------------
E
----
K
R
G
M
G
S
S
A
A
I
S
I
A
A
I
R
A
V
F
D
---------------
Y
Y
Q
A
---------------
D
L
P
H
D
V
L
E
I
L
V
N
R
A
E
M
I
---
A
H
M
-
N
P
-
S
G
L
-
D
A
K
T
C
L
S
D
Q
-----
P
I
R
F
I
K
N
V
G
----------------------------------
F
T
E
L
E
M
D
-
L
--
S
A
Y
----
L
V
I
A
D
T
G
V
-
Y
G
H
T
------------
R
E
-
A
I
Q
V
V
-------
Q
N
K
G
K
-----------------------
D
A
L
P
---------
F
L
H
---
A
----
L
--
G
E
L
T
Q
Q
A
E
I
A
-------
I
S
Q
K
D
A
E
G
L
G
Q
I
L
S
Q
A
H
L
H
L
K
E
I
--
G
V
----------
S
S
L
E
A
D
S
L
V
E
T
A
L
S
-
H
G
-
A
L
G
--
A
-
K
M
S
G
G
G
L
G
G
C
I
I
A
L
---
V
---
T
N
L
T
H
A
---
Q
E
L
A
E
R
L
E
E
K
G
A
V
Q
T
W
-------------------------
32
HHSearch
54.90
18%
-77
- C1 -
2CZ9
3
GAL1_PYRHO
A:
[1-327]
-------------------
M
-
I
K
V
K
S
P
G
R
V
N
L
I
G
E
H
T
D
Y
T
------
Y
G
Y
-
V
M
P
M
A
I
--
N
-
L
-
Y
T
-
K
I
E
A
E
K
H
G
---
E
V
I
L
Y
----
S
E
H
F
G
E
--
E
--
R
K
---------
F
S
L--
N
--
D
L
--
R
---
K
-
E
N
-
S
W
I
D
Y
V
K
G
I
F
W
-----------
V
L
K
E
S
----
D
Y
E
V
G
G
I
K
G
R
V
S
G
------------
N
L
P
----
L
----
G
A
G
L
S
S
S
A
S
F
E
V
G
I
L
E
T
L
D
K
---------------
L
Y
N
L
---------------
K
L
D
S
L
S
K
V
L
L
A
K
K
A
E
N
E
---
F
V
G
-
V
P
C
G
I
L
-
D
Q
F
A
V
V
F
G
R
-----
E
G
N
V
I
F
L
D
T
H
T
------------------------------
L
D
Y
E
Y
I
P
F
P
-
K
--
D
V
S
----
I
L
V
F
Y
T
G
V
-
R
----------------
S
S
E
Y
A
E
R
K
H
I
A
E
E
S
L
K
I
L
G
------
K
GSSKEVREGELSK
L
P
P
L
H
R
K
---------
F
F
G
Y
I
V
R
----
E
--
N
A
R
V
L
E
V
R
D
A
-------
L
K
E
G
N
V
E
E
V
G
K
I
L
T
T
A
H
W
D
L
A
K
N
--
Y
E
---------
V
S
C
K
E
L
D
F
F
V
E
R
A
L
K
-
L
G
-
A
Y
G
--
A
-
R
L
T
G
A
G
F
G
G
S
A
I
A
L
---
V
---
D
K
E
D
-
A
---
E
T
I
G
E
E
I
L
R
--------------------------------
46
Fugue
52.31
20%
-64
- C1 -
2OI2
2
?
A:
[4-292]
------------------
K
V
-
G
V
G
Q
A
H
S
K
I
I
L
I
G
E
H
A
V
V
Y
-----
G
Y
P
A
-
I
S
L
P
L
L
--
E
-
V
-
E
V
-
T
C
K
V
V
P
A
E
S
P
---------------------------------------------------------
W
R
L
Y
E
E
D
-----------
T
L
S
M
A
V
Y
A
S
L
E
Y
L
N
I
T
E
A
C
I
R
C
------------
E
I
--------
D
E
K
R
G
M
G
S
S
A
A
I
S
I
A
A
I
R
A
V
F
D
---------------
Y
Y
Q
A
---------------
D
L
P
H
D
V
L
E
I
L
V
N
R
A
E
M
I
---
A
H
M
-
N
P
-
S
G
L
-
D
A
K
T
C
L
S
D
Q
-----
P
I
R
F
I
K
-
N
V
G
F
T
E
L
E
M
D
L
S
-----------------------------------
A
-
Y
----
L
V
I
A
D
T
G
V
-
Y
G
H
T
------------
R
E
-
A
I
Q
V
V
-------
Q
N
K
G
-----------------------
K
D
A
L
P
---------
F
L
H
---
A
----
L
--
G
E
L
T
Q
Q
A
E
I
A
-------
I
S
Q
K
D
A
E
G
L
G
Q
I
L
S
Q
A
H
L
H
L
K
E
I
--
G
----------
V
S
S
L
E
A
D
S
L
V
E
T
A
L
S
-
H
G
A
L
-
G
--
A
-
K
M
S
G
G
G
L
G
G
C
I
I
A
L
---
V
---
T
N
L
T
H
A
---
Q
E
L
A
E
R
L
E
E
K
G
A
V
Q
T
W
I
E
S
L
---------------------
28
HHSearch
51.60
16%
-62
- C1 -
1PIE
2
GAL1_LACLA
A:
[41-391]
-------------
V
F
G
D
T
K
E
V
E
Y
F
F
S
P
G
R
I
N
L
I
G
E
H
T
D
Y
N
------
G
G
Y
-
V
F
P
A
S
I
--
T
-
I
-
G
T
-
T
G
L
A
R
L
R
E
D
K
-
K
V
K
L
Y
----
S
E
N
F
P
K
--
L
G
V
I
E
---------
F
D
L--
D
--
E
V
EK
K
---
D
-
G
E
-
L
W
S
N
Y
V
K
G
M
I
V
-----------
M
L
K
G
A
G
---
Y
E
I
D
K
G
F
E
L
L
I
K
G
------------
E
I
P
----
T
----
A
S
G
L
S
S
S
A
S
L
E
L
L
V
G
V
V
L
D
D
---------------
L
F
N
L
---------------
N
V
P
R
L
E
L
V
Q
L
G
Q
K
T
E
N
D
---
Y
I
G
-
V
N
-
S
G
I
L
D
Q
F
A
I
G
F
G
E
-----
V
K
K
A
I
E
L
D
C
N
T
------------------------------
L
K
Y
E
M
V
P
V
E
L
R
--
D
Y
D
----
I
V
I
M
N
T
N
K
-
P
R
A
L
TE
S
K
Y
N
E
R
F
A
E
T
R
E
-
A
L
K
R
M
-------
Q
T
R
L
D
IQSLGE
L
-------------
S
N
E
E
F
D
A
N
TDLIGD
E
T
L
I
K
---
R
A
R
H
A
V
Y
E
N
N
R
T
K
I
A
Q
K
A
-------
F
V
A
G
N
L
T
K
F
G
E
L
L
N
A
S
H
A
S
L
K
D
D
--
Y
E
---------
V
T
G
L
E
L
D
T
L
A
E
T
A
Q
K
Q
A
G
-
V
L
G
--
A
-
R
M
T
G
A
G
F
G
G
C
A
I
A
L
---
V
---
A
H
D
N
-
V
---
S
A
F
R
K
A
V
G
---------------------------------
47
Fugue
50.05
16%
-50
- C1 -
1PIE
2
GAL1_LACLA
A:
[29-416]
T
V
L
S
A
L
T
E
K
F
A
E
V
F
G
D
T
K
E
V
-
E
Y
F
F
S
P
G
R
I
N
L
I
G
E
H
-
T
D
Y
-----
N
G
G
Y
-
V
F
P
A
S
I
--
T
-
I
-
G
T
-
T
G
L
A
R
L
R
E
D
K
-
K
V
K
L
Y
S
ENF
P
K
L
G
V
I
--
E
--
F
D
---------
L
D
---
E
--
V
E
--
K
---
K
-
D
G
-
E
L
W
---
S
N
Y
V
K
-----------
G
M
I
V
M
L
K
G
A
G
Y
E
I
D
K
G
F
E
L
L
I
K
------------
G
E
I
----
P
T
A
S
---
G
L
S
S
S
A
S
L
E
L
L
V
G
V
V
L
D
D
---------------
L
F
N
L
---------------
N
V
P
R
L
E
L
V
Q
L
G
Q
K
T
E
N
D
---
Y
I
G
V
N
S
-
G
I
L
-
D
Q
F
A
I
G
F
G
E
VKKAI
E
L
D
C
N
T
L
K
Y
E
M
V
P
V
E
L
R
D
Y
D
I
V
I
M
N
TNKPRALTE
S
K
Y
N
E
R
F
A
E
T
R
E
A
L
K
R
-
M
--
Q
-
T
----
R
L
D
I
Q
S
L
G
-
E
L
S
N
------------
E
E
-
F
D
A
N
T
-------
D
L
I
G
D
------
E
-------------
T
L
I
K
R
A
R
---------
H
A
V
---
Y
----
E
--
N
N
R
T
K
I
A
Q
K
A
-------
F
V
A
G
N
L
T
K
F
G
E
L
L
N
A
S
H
A
S
L
K
D
----------
D
Y
-
E
V
T
G
L
E
L
D
T
L
A
E
T
A
Q
K
-
Q
A
-
G
-
V
L
G
A
-
R
M
T
G
A
G
F
G
G
C
A
I
A
L
---
V
---
A
-
H
D
N
V
---
S
A
F
R
K
A
V
G
Q
V
Y
E
E
V
V
G
Y
P
A
S
F
--
Y
V
A
Q
I
G
S
G
S
TKL------
48
Fugue
49.47
18%
-58
- C1 -
1H74
2
KHSE_METJA
A:
[1-296]
------------------
M
K
-
V
R
V
K
A
P
C
T
S
A
N
L
G
-----------
V
G
F
D
-
V
F
G
L
C
L
--
K
-
E
-
P
Y
D
V
I
E
V
E
A
I
D
D
K
-
E
I
I
I
E
----
V
D
---------------------
D
---
K
--
N
I
--
P
---
T
-
D
P
-
D
K
N
V
A
G
I
V
A
K
K
-----------
M
I
D
D
F
N
I
G
K
G
V
K
I
T
I
K
K
G
V
-------------------------
K
A
G
S
G
L
G
S
S
A
A
S
S
A
G
T
A
Y
A
I
N
E
---------------
L
F
K
L
---------------
N
L
D
K
L
K
L
V
D
Y
A
S
Y
G
E
L
A
---
S
S
G
-
A
K
-
H
A
D
-
N
V
A
P
A
I
F
G
G
-----
F
T
M
V
T
N
Y
E
P
L
E
V
L
H
I
P
I
D
F
K
L
D
I
L
----------
I
A
I
P
N
I
S
I
N
T
K
E
A
R
E
I
-
L
--
P
------------------------------------------------------------------------
K
A
V
G
L
K
---------
D
L
V
---
N
----
N
--
V
G
K
A
C
G
M
V
Y
A
-------
L
Y
N
K
D
K
S
L
F
G
R
Y
M
M
S
D
K
V
I
E
P
V
R
--
G
K
L
---
I
-------
P
N
Y
F
K
I
K
E
E
V
K
D
-
K
V
-
Y
-
G
--
I
-
T
I
S
G
S
G
P
S
I
I
A
F
P
K
---
E
---
E
F
I
D
E
V
---
E
N
I
L
R
D
Y
Y
E
N
T
I
R
T
E
V
G
K
G
V
E
--
V
V
----------------
37
HHSearch
49.16
21%
-70
- C1 -
3HUL
2
KHSE_LISMO
A:
[2-271]
-------------------
S
-
L
R
I
R
V
P
A
T
T
A
N
L
G
P
-----------
G
F
D
-
S
C
G
L
A
L
--
T
-
L
-
Y
L
-
T
L
D
I
G
A
E
A
D
--
S
W
Y
I
E
----
H
N
I
-
G
G
-------------------------
G
--
I
---
P
--
H
-
D
E
T
N
V
I
I
E
T
A
L
-----------
N
L
A
P
-------
N
L
T
P
H
H
L
V
M
T
C
------------
D
I
P
----
P
----
A
R
G
L
G
S
S
S
A
A
V
V
A
G
I
E
L
A
N
T
---------------
L
A
E
L
---------------
N
L
S
K
E
E
K
V
R
I
A
A
E
I
E
----------
G
-
H
P
D
-
N
V
A
P
A
V
L
G
N
-----
W
V
V
G
A
K
L
D
G
E
D
--------------------------------
F
Y
V
R
H
L
F
-
P
---C
A
----
L
I
A
F
I
P
K
A
-
E
L
L
----------------------------
P
D
T
L
------------------------
P
F
K
E
---------
A
V
Q
--------
A
--
S
S
I
A
N
V
M
I
A
A
-------
I
L
R
N
D
M
T
L
A
G
E
M
M
E
R
D
L
W
-------
S
Q
----------
L
V
P
H
L
A
Q
I
R
D
V
A
K
N
-
Q
G
-
A
Y
A
--
A
-
C
L
S
G
A
G
P
--
T
V
L
V
F
---
A
---
P
R
N
L
-
A
---
N
K
L
Q
T
S
L
Q
T
L
E
------------------------------
50
Fugue
48.92
17%
-60
- C1 -
1FWK
1
KHSE_METJA
A:
[1-296]
-------------------------
M
K
V
R
V
K
A
P
C
T
S
A
N
L
G
-----
V
G
F
D
-
V
F
G
L
C
L
--
K
-
E
-
P
Y
D
V
I
E
V
E
A
I
D
D
K
-
E
I
I
I
E
----
V
D
---------------------
D
---
K
--
N
I
--
P
---
T
-
D
P
-
D
K
N
V
A
G
I
V
A
K
K
-----------
M
I
D
D
F
N
I
G
K
G
V
K
I
T
I
K
K
G
V
-------------------------
K
A
G
S
G
L
G
S
S
A
A
S
S
A
G
T
A
Y
A
I
N
E
---------------
L
F
K
L
---------------
N
L
D
K
L
K
L
V
D
Y
A
S
Y
G
E
L
A
---
S
S
G
-
A
K
-
H
A
D
-
N
V
A
P
A
I
F
G
G
-----
F
T
M
V
T
N
Y
E
P
L
E
V
L
H
I
P
I
D
F
K
L
D
I
L
----------
I
A
I
P
N
I
S
I
N
T
K
E
A
R
E
I
-
L
--
P
------------------------------------------------------------------------
K
A
V
G
L
K
---------
D
L
V
---
N
----
N
--
V
G
K
A
C
G
M
V
Y
A
-------
L
Y
N
K
D
K
S
L
F
G
R
Y
M
M
S
D
K
V
I
E
P
V
R
--
G
K
L
---
I
-------
P
N
Y
F
K
I
K
E
E
V
K
D
-
K
V
-
Y
-
G
--
I
-
T
I
S
G
S
G
P
S
I
I
A
F
P
K
---
E
---
E
F
I
D
E
V
---
E
N
I
L
R
D
Y
Y
E
N
T
I
R
T
E
V
G
K
G
V
E
--
V
V
----------------
34
HHSearch
48.88
17%
-67
- C1 -
1H72
3
KHSE_METJA
C:
[1-290]
------------------
M
K
-
V
R
V
K
A
P
C
T
S
A
N
L
G
V
G
F
D
------------
V
F
G
L
C
L
--
K
E
P
-
Y
D
-
V
I
E
V
E
A
I
D
D
K
-
E
I
I
I
E
----
V
D
-
D
K
--------------------------
N
--
I
---
P
-
T
D
-
P
D
K
N
V
A
G
I
V
A
K
-----------
K
M
I
D
D
F
---
N
-
I
G
K
G
V
K
I
T
I
K
K
------------
G
V
K
----
A
----
G
S
G
L
G
S
S
A
A
S
S
A
G
T
A
Y
A
I
N
E
---------------
L
F
K
L
---------------
N
L
D
K
L
K
L
V
D
Y
A
S
Y
G
E
L
A
---
S
S
G
-
A
K
-
H
A
D
-
N
V
A
P
A
I
F
G
G
-----
F
T
M
V
T
N
Y
E
P
L
--------------------------------
E
V
L
H
I
P
I
D
-
F
--
K
L
D
----
I
L
I
A
I
P
N
I
-
S
I
N
T
------------
K
E
-
A
R
E
I
L
-------
P
K
A
V
G
------------------------
L
K
D
---------
L
V
N
---
N
----
V
--
G
K
-
A
C
G
M
V
Y
A
-------
L
Y
N
K
D
K
S
L
F
G
R
Y
M
M
S
D
K
V
I
E
P
V
R
--
G
K
----------
L
I
P
N
Y
F
K
I
K
E
E
V
K
D
--
K
-
V
Y
G
--
I
-
T
I
S
G
S
G
P
--
S
I
I
A
F
---
P
---
K
E
E
F
-
I
---
D
E
V
E
N
I
L
R
D
Y
Y
E
N
T
I
R
T
E
V
G
---------------------
41
HHSearch
48.83
14%
-69
- C1 -
3QT5
-
?
A:
[1-307]
----------------
M
V
K
S
-
G
K
A
R
A
H
T
N
I
A
L
I
K
Y
W
G
K
A
D
ETYII
P
M
N
N
-
S
L
S
V
T
L
--
D
-
R
F
Y
T
-
E
T
K
V
T
F
D
P
D
F
T
E
D
C
L
I
----
L
N
G
N
------------------------------
E
---
V
-
N
A
-
K
E
K
E
K
I
Q
N
Y
M
N
-----------
I
V
R
D
L
A
----
G
N
R
L
H
A
R
I
E
S
E
N
------------
Y
V
P
----
T
----
A
A
G
L
A
S
S
A
S
A
Y
A
A
L
A
A
A
C
N
E
---------------
A
L
S
L
---------------
N
L
S
D
T
D
L
S
R
L
A
R
R
G
S
-------------
G
--
S
A
S
R
S
I
F
G
G
-----
F
A
E
W
E
K
G
H
D
D
L
T
S
Y
------
A
H
--------------------
G
I
N
S
N
G
W
E
-
K
D
L
S
M
I
----
F
V
V
I
N
N
Q
S
-
K
K
-
S
------------
R
S
-
G
M
S
L
T
-------
R
D
T
S
R
-----------------------
F
Y
Q
Y
---------
W
L
D
---
H
----
V
--
D
E
D
L
N
E
A
K
E
A
-------
V
K
N
Q
D
F
Q
R
L
G
E
V
I
E
A
N
G
L
R
M
H
A
T
N
L
G
A
Q
PPF
T
Y
L
-
V
Q
E
S
Y
D
A
M
A
I
V
E
Q
C
R
K
-
A
N
-
L
-
P
--
C
-
Y
F
T
M
D
A
G
P
-
N
V
K
V
L
---
V
---
E
K
K
N
-
K
---
Q
A
V
M
E
Q
F
L
K
V
-------------------------------