@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0019: (2016-03-11 )
MGTFFSKWGKWILVLGLVFSVFSVSTAGQAAAKETVINKQMVTTASLNVRSTNSTSGKVIGWLKNNTKFKAIAKTSNNWYRFSFKGKNGYVSGKYVKAATATPTPKPPTPKIVQMNVPLIVQRPQLPTGCEITNIAMMLRYAGKNVDKVKLAKEMKRHKSNPNYGFVGNPFSKSGWTIYPPALVNQVKKYTGSAKNMTGTNLAGIKNQLNKKRPVVAWVSKFHGFSVHAITITGYDKNNFYYNDSWSGQKNARISQSYFNTCWSKQAKRAISY
Atome Classification :
(20 SA)
-----------------------.....---....10........20........30........----------40...--.....50..---...-...60........70--........80........90.....---------------...100.......110.......-120.---......130----------------------.......-.140...--.--..-----..150.....-------..-------160.......--170..--.--......180.......190-..-...---.-.--.200----.......210--.....----------------...--------------------220---.------------------.---------------------....----..230.....----.-----.240......----.250.......260---------.---......270.-------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------MG
T
F
F
---
S
K
W
G
K
W
I
L
V
L
G
L
V
F
S
V
F
SVSTAGQ
A
A
A
K
E
T
VINK----------
Q
M
V
T
T
--
A
S
L
N
V
R
STN---STS-
G
K
V
I
G
W
LKNN
T
K
F
K
A
--
I
A
KTSN
N
W
Y
R
F
S
F
KGKNGYVS
G
K
Y
V
---------------
K
AATATPTPKPPT
P
K
I
V
Q
MNV
P
L
-
I
V
QR---PQLPTGC
E
-----------------------
I
T
N
I
A
M
M
-
L
R
Y
-AGK--N--
V
D
-----
K
V
K
L
A
K
E
M
K
R
-------HK-------SNPNYGFVGN--P--FS--K--SG
W
T
IY
P
P
A
L
V
N
Q
V
K
K
Y-T-GS-AKN---M-T--GT
N
L
----
A
G
I
K
N
Q
LN-K--KR
P
V
V
----------------
A
W
V
--------------------
S
K----F------------------H---------------------G
F
S
V
----
H
A
I
T
I
T
G
YDK----N-----
N
F
Y
YNDSWSG----QKNA
R
I
S
Q
S
Y
F
N
T
C
---------
W
---
S
K
Q
A
K
R
AISY-------------------------
21
HHSearch
93.32
37%
-87
- C5 -
3ERV
2
?
A:
[31-223]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
I
L
S
N
V
P
F
-
I
Q
Q
L
---
P
E
L
D
R
G
C
E
-----------------------
V
T
S
L
A
M
M
-
L
Q
Y
-
A
G
I
--
T
--
V
D
-----
K
M
K
L
A
N
E
I
K
K
-------
V
D
FMNDG
V
R
G
N
P
N
E
G
F
V
G
N
--
I
--
Y
T
--
F
S
E
S
G
Y
G
V
Y
H
G
P
L
F
Q
L
A
K
K
Y
L
P
-
N
K
-
A
V
D
---
L
-
T
--
G
K
S
I
----
E
E
L
Y
K
S
V
K
-
A
--
G
Q
P
V
V
----------------
I
I
T
--------------------
N
-----
A
------------------
T
FAPLDEDE
F
T
T
W
E
T
NN
G
D
V
S
I
T
Y
N
E
----
H
C
V
V
L
I
G
Y
D
Q
----
E
-----
S
V
Y
I
R
D
P
L
K
D
----
S
L
D
V
K
V
P
R
E
K
F
E
Q
A
---------
W
---
V
Q
M
G
S
Q
A
I
S
Y
-------------------------
43
Fugue
92.59
36%
-81
- C5 -
3ERV
2
?
A:
[29-228]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
E
K
V
I
L
S
N
V
P
F
-
I
Q
Q
L
---
P
E
L
D
R
G
C
E
-----------------------
V
T
S
L
A
M
M
-
L
Q
Y
-
A
G
I
--
T
--
V
D
-----
K
M
K
L
A
N
E
I
K
K
V
D
FMNDG
V
R
-------
G
N
P
N
E
G
F
V
G
N
--
I
--
Y
T
FS
E
--
S
G
Y
G
V
Y
H
G
P
L
F
Q
L
A
K
K
Y
-
L
-
P
N
K
A
V
D
---
L
-
T
--
G
K
S
I
----
E
E
L
Y
K
S
V
K
-
A
--
G
Q
P
V
V
----------------
I
I
T
N
ATFAPLDEDE
F
T
T
W
E
T
NN
G
D
V
----
S
------------------
I
---------------------
T
Y
N
E
----
H
C
V
V
L
I
G
Y
D
Q
----
E
-----
S
V
Y
I
R
D
P
L
K
D
----
S
L
D
V
K
V
P
R
E
K
F
E
Q
A
---------
W
---
V
Q
M
G
S
Q
A
I
S
Y
V
KRSK--------------------
1
PsiBlast_PDB
89.27
33%
-75
- C5 -
3ERV
2
?
A:
[31-223]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
I
L
S
N
V
P
F
-
I
Q
Q
L
---
P
E
L
D
R
G
C
E
-----------------------
V
T
S
L
A
M
M
-
L
Q
Y
-
A
G
I
--
T
--
V
D
-----
K
M
K
L
A
N
E
I
K
K
V
D
FMNDG
V
R
-------
G
N
P
N
E
G
F
V
G
N
IY
T
--
F
S
--
E
--
S
G
Y
G
V
Y
H
G
P
L
F
Q
L
A
K
K
Y
-
L
P
N
K
-
A
V
D
---
L
-
T
--
G
K
S
I
----
E
E
L
Y
K
S
V
K
-
A
--
G
Q
P
V
V
I
I
T
N
ATFAPLDEDE
F
T
T
W
E
--------------------
T
N
----
N
------------------
G
---------------------
D
V
S
I
T
YN
E
H
C
V
V
L
I
G
Y
D
Q
----
E
-----
S
V
Y
I
R
D
P
L
K
D
----
S
L
D
V
K
V
P
R
E
K
F
E
Q
A
---------
W
---
V
Q
M
G
S
Q
A
I
S
Y
-------------------------
22
HHSearch
62.87
18%
-75
- C5 -
3K8U
-
?
A:
[5-133]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
Y
K
L
-
V
P
Q
I
---
D
--
T
R
D
C
G
-----------------------
P
A
V
L
A
S
V
-
A
K
H
-
Y
G
S
--
N
--
Y
S
-----
I
A
Y
L
R
E
L
S
K
T
-------
N
K
-------------------------------
Q
G
T
T
A
L
G
I
V
E
A
A
K
K
L
-
G
-
F
E
-
T
R
S
---
I
-
K
--
A
-
D
M
----
T
L
F
-
D
Y
N
D
-
L
--
T
Y
P
F
I
----------------
V
H
V
---------------------
I
----
K
------------------
G
---------------------
K
R
L
Q
----
H
Y
Y
V
V
Y
G
S
Q
N
----
N
-----
Q
L
I
I
G
D
P
D
P
S
----
V
K
V
T
R
M
S
K
E
R
F
Q
S
E
---------
W
---
T
G
---------------------------------
52
Fugue
60.08
15%
-19
- C3 -
4QVG
-
?
A:
[4-344]
------------------ELSAL
V
P
V
L
F
---
G
H
A
A
F
Q
Q
L
N
A
G
C
Q
L
G
L
F
E
L
L
H
E
R
G
P
L
S
A
E
E
V
A
D
A
L
RLP
R
R
S
A
D
I
L
L
L
G
T
--
T
A
L
G
L
S
T
V
T
DGG
Y
R
N
-
G
A
P
I
G
A
A
F
R
D
G
L
W
P
V
--
L
R
D
I
V
Q
Y
Q
D
K
I
A
Y
Q
P
A
A
D
Y
V
E
S
L
R
T
GQNAGIRHFPGTTRD
L
Y
S
R
L
A
A
V
P
G
L
E
E
L
F
Y
R
G
M
H
A
W
S
-
Q
L
S
N
---
P
V
L
L
A
Q
P
D
-----------------------
F
T
R
V
H
R
V
-
L
D
V
G
G
G
D
--
A
--
V
N
-----
A
V
A
L
A
R
A
-----------
H
-------
P
S
L
R
V
T
V
L
D
R
--
P
G
A
L
E
--
V
--
A
R
K
T
I
A
E
A
G
L
E
E
R
V
R
T
H
-
A
-
A
D
-
I
F
T
D
S
Y
P
-
A
--
G
H
D
C
----
V
L
F
A
H
Q
L
V
-
I
WS
P
E
Q
N
L
----------------
T
L
L
--------------------
R
K
----
A
------------------
Y
---------------------
D
A
V
E
----
P
G
G
R
V
L
V
F
N
A
------------
F
T
D
D
D
R
T
G
----
P
L
Y
A
A
L
D
N
V
Y
F
T
T
L
PF
R
H
S
T
IHR
W
---
A
D
C
E
S
W
L
R
E
A
GFTD
V
G
R
T
A
P
P
GWTP
H
G
V
V
S
G
S
R
P
R
49
Fugue
59.19
19%
-41
- C2 -
4INO
-
?
A:
[1-302]
Q
E
V
K
V
K
D
YF
G
E
Q
T
I
K
L
PVS
K
I
I
Y
L
G
S
F
A
E
V
P
A
M
F
H
T
W
D
R
V
V
G
I
S
D
Y
A
F
K
-
S
D
I
V
K
A
T
L
K
D
P
E
R
I
K
----------
P
M
S
S
D
HA
A
A
L
N
V
E
L
L
K
---
K
L
S
P
D
L
V
V
T
F
V
G
N
P
K
A
V
E
H
--
A
K
K
F
G
I
S
F
L
S
F
Q
E
K
T
-
I
A
E
V
M
E
D
I
D
---------------
T
Q
A
K
A
L
E
V
D
A
S
K
K
L
A
K
M
Q
E
T
L
D
F
-
I
A
E
R
L
KG
V
K
K
K
K
G
V
E
L
F
HKAN
K
I
S
G
H
QA
L
D
S
D
I
L
E
K
G
G
I
D
N
F
G
L
K
Y
V
K
F
-
G
R
A
--
D
--
I
S
-----
V
E
K
I
V
K
E
--------------------
N
P
E
I
I
F
I
W
W
--
I
--
S
P
--
L
--
S
P
E
D
V
L
N
N
P
K
F
A
T
I
K
A
I
K
N
-
K
Q
-
V
Y
K
---
L
-
P
--
T
M
D
I
----
G
G
------------
P
R
A
----------------
P
L
I
--------------------
S
L
----
F
------------------
I
---------------------
A
L
K
A
----
H
-----------------------
P
E
A
F
K
G
----
V
D
I
N
A
I
V
K
D
Y
Y
K
V
V
---------
F
DLN
D
A
E
V
E
P
F
L
W
H
-------------------------
42
HHSearch
57.89
23%
-75
- C5 -
3OIS
-
?
A:
[190-276]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
----
D
H
L
K
A
C
L
A
-
V
--
G
S
P
F
V
----------------
F
G
F
--------------------
S
V
----
Y
NSWVGNNSLPVRIPLPTK
N
DT-------------------
L
E
G
G
----
H
A
V
L
C
V
G
Y
D
D
EI--
R
-----
H
F
R
I
R
N
S
W
G
N
NVGE
D
G
Y
F
W
M
P
Y
E
Y
I
S
N
-------------------------------------------------
47
Fugue
56.94
16%
-52
- C5 -
3K8U
-
?
A:
[5-141]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
Y
-
K
L
V
P
---
Q
I
D
T
R
D
C
G
-----------------------
P
A
V
L
A
S
V
-
A
K
H
-
Y
G
S
--
N
--
Y
S
-----
I
A
Y
L
R
E
L
S
K
--------------------------------
T
N
--
K
--
Q
G
T
T
A
L
G
I
V
E
A
A
K
K
L
G
F
-
E
-
T
R
-
S
I
K
---
A
-
D
--
M
T
L
F
----
D
Y
N
D
L
T
Y
-------
P
F
I
----------------
V
H
V
--------------------
I
K
-----------------------
G
---------------------
K
R
L
Q
----
H
Y
Y
V
V
Y
G
S
Q
N
----
N
-----
Q
L
I
I
G
D
P
D
P
S
----
V
K
V
T
R
M
S
K
E
R
F
Q
S
E
---------
W
---
T
G
L
A
I
F
L
A
P
Q
-------------------------
26
HHSearch
53.84
14%
-70
- C5 -
2BU3
3
?
A:
[68-232]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
M
Q
F
-
V
T
Q
V
---
N
--
Q
A
Y
C
G
-----------------------
V
A
S
I
I
M
V
-
L
N
S
-
L
G
I
--
N
--
A
-Y
R
V
F
T
Q
D
N
F
F
S
---
T
-------
K
-------------
A
V
I
A
P
-----
E
V
--
V
--
A
R
Q
G
M
T
L
D
E
L
G
R
L
I
A
S
Y
-
G
-
V
K
-
V
K
V
---
N
-
H
AS
D
T
N
I
E
D
F
R
K
Q
V
A
E
N
L
K
Q
D
--
G
N
F
V
I
----------------
V
N
Y
--------------------
L
R
----
K
------------------
E
IGQ------------------
E
R
G
G
----
H
I
S
P
L
A
A
Y
N
E
QT--
D
-----
R
F
L
I
M
D
V
S
R
Y
K---
Y
P
P
V
W
V
K
T
T
D
L
W
K
A
---------
M
--------------------------------------
34
HHSearch
51.71
42%
-38
- C5 -
2KT8
-
?
A:
[11-67]
----------------------------------------------------------------------------------
S
S
L
N
V
R
E
G
A
---
S
T
S
-
S
K
V
I
G
S
L
S
G
N
T
K
V
T
I
--
V
G
E
-
E
G
A
F
Y
K
I
E
Y
K
G
S
H
G
Y
V
A
K
E
Y
I
---------------
K
D
I
K
D
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
51.41
11%
-62
- C5 -
1X9Y
-
SSPB_STAAU
A:
[228-365]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
K
N
F
K
I
R
E
Q
Q
F
---
D
--
N
S
W
C
A
-----------------------
G
F
S
M
A
A
L
-
L
N
A
-
T
K
N
--
T
DT
Y
N
-----
A
H
D
I
M
R
T
L
Y
P
-------
E
V
-------
S
E
-------
Q
--
D
--
L
P
------
N
C
A
T
F
P
N
Q
M
I
E
Y
G
K
S
Q
-
G
-
R
D
-
I
H
Y
Q
--
E
-
G
--
V
P
S
Y
----
N
Q
V
D
Q
L
T
K
-
D
--
N
V
G
I
M
----------------
I
L
A
--------------------
Q
S
----
V
SQNP--------------
N
D--------------------
P
H
L
G
----
H
A
L
A
V
V
G
N
A
K
I
ND
Q
E
-----
K
L
I
Y
W
N
P
W
D
T
----
E
-------------------------------------------------------------
23
HHSearch
51.38
11%
-40
- C5 -
1CV8
2
A:
[17-155]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
Q
G
---
N
--
N
G
W
C
A
-----------------------
G
Y
T
M
S
A
L
-
L
N
A
-
T
Y
N
TN
K
--
Y
H
-----
A
E
A
V
M
R
F
L
H
P
-------
N
L
-------
Q
G
-------
Q
--
Q
--
F
Q
------
F
T
G
L
T
P
R
E
M
I
Y
F
G
Q
T
Q
-
G
-
R
S
-
P
Q
L
---
L
N
R
--
M
T
T
Y
----
N
E
V
D
N
L
T
K
-
N
--
N
K
G
I
A
----------------
I
L
G
--------------------
S
R
VESR
N
------------------
G
---------------------
M
H
A
G
----
H
A
M
A
V
V
G
N
A
K
----
L
NNG
Q
E
V
I
I
I
W
N
P
W
D
N
----
G
F
-
M
T
Q
D
A
K
N
N
---------------------------------------------------
30
HHSearch
49.76
35%
-38
- C5 -
2KRS
-
?
A:
[8-67]
-------------------------------------------------------------------------------
N
--
S
A
L
N
M
R
S
G
P
---
G
S
N
-
Y
G
V
I
G
T
L
R
N
N
D
K
V
E
I
--
I
K
E
-
V
D
G
W
Y
E
I
R
F
N
G
K
V
G
Y
A
S
K
S
Y
I
---------------
T
I
V
N
E
G
S
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
HHSearch
49.61
10%
-66
- C5 -
1PXV
2
SSPB_STAAU
A:
[16-155]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
T
L
K
N
F
K
I
-
R
E
Q
Q
---
F
D
-
N
S
W
A
A
-----------------------
G
F
S
M
A
A
L
-
L
N
A
-
T
K
N
TD
T
--
Y
N
-----
A
H
D
I
M
R
T
L
Y
P
-------
E
V
-------
S
-
E
------
Q
--
D
--
L
------
P
N
C
A
T
F
P
N
Q
M
I
E
Y
G
K
S
Q
-
G
-
R
D
-
I
H
Y
---
Q
E
G
--
V
P
S
Y
----
N
Q
V
D
Q
L
T
K
-
D
--
N
-
V
G
I
----------------
M
I
L
--------------------
A
Q
----
S
V
S
QNPN------------
D
---------------------
P
H
L
G
----
H
A
L
A
V
V
G
N
A
K
I
N--
D
Q
E
---
K
L
I
Y
W
N
P
W
D
T
----
E
-------------------------------------------------------------
9
PsiBlast_PDB
49.05
29%
-42
- C5 -
4KRT
4
?
A:
[232-296]
------------------------------------------------------------------------------------
L
N
I
R
A
K
G
---
T
T
N
-
S
K
I
I
G
S
I
P
A
G
E
T
F
K
I
KW
V
D
E
D
Y
L
G
W
Y
Y
V
E
Y
N
G
V
V
G
Y
V
N
A
D
Y
V
---------------
E
K
L
Q
M
A
T
T
Y
N
V
S
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
48.82
40%
-27
- C5 -
2KT8
-
?
A:
[1-62]
--------------------------------------------------------
A
E
K
T
G
I
V
N
--------------
V
S
--
S
S
L
N
V
R
E
G
A
---
S
T
S
-
S
K
V
I
G
S
L
S
G
N
T
K
V
T
I
--
V
G
E
-
E
G
A
F
Y
K
I
E
Y
K
G
S
H
G
Y
V
A
K
E
Y
I
---------------
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
47.39
42%
-33
- C5 -
2KRS
-
?
A:
[9-59]
----------------------------------------------------------------------------------
S
A
L
N
M
R
S
G
P
---
G
S
N
-
Y
G
V
I
G
T
L
R
N
N
D
K
V
E
I
--
I
-
K
E
V
D
G
W
Y
E
I
R
F
N
G
K
V
G
Y
A
S
K
S
Y
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
44.99
45%
-19
- C5 -
2KYB
-
?
A:
[9-60]
-------------------------------------------------------------------------------
S
--
S
S
L
N
V
R
S
S
A
---
S
T
S
-
S
K
V
I
G
S
L
S
G
N
T
K
V
T
I
--
V
G
E
-
E
G
A
F
Y
K
I
E
Y
K
G
S
H
G
Y
V
A
K
E
Y
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
HHSearch
43.93
11%
-56
- C5 -
1DEU
-
CATZ_HUMAN
A:
[137-203]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
R
----
E
K
M
M
A
E
I
Y
-
A
--
N
G
P
I
S
----------------
C
G
I
--------------------
M
A
----
T
E
R
L
A
N
YTGGI
Y
A
E
Y
Q
D--
T
---------------------
T
Y
I
N
----
H
V
V
S
V
A
G
W
G
I
S
DG
T
E
-----
Y
W
I
V
R
N
S
W
G
-------------------------------------------------------------------
15
PsiBlast_PDB
42.25
31%
-35
- C5 -
2CUB
-
A:
[36-76]
--------------------------------------------------------------------------------------------------------
L
I
K
G
T
K
V
I
V
--
M
E
K
C
S
D
G
W
W
R
G
S
Y
N
G
Q
V
G
W
F
P
S
N
Y
V
---------------
T
E
E
G
D
S
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------