@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0048: (2016-03-11 )
LSNFTAKVPLSERMADVLISKDRWKDDEEGYLKVKYGLEIILINVMKFALVYGIALVTGLLLQTVTVHLSYLWLRRYSFGLHATKTLNCTLISLLMFVLAPFVFQNIPSNNWIVLGTFGFILLNMFLFAPADTESLPLIGEEHRKTLKRKAMIGTLILTGIALLIPFAEMKTLIMVGSLFQVISINPLTYKLLKRRYRNYEKYE
Atome Classification :
(20 SA)
--------------------------------------------------------------------------------------------------......--...10.......----.20.------.......---.30...-.....40........50..--......60...-.....70......-..80...---.....90........100..----------------.-....110...--...-.120.--------.-----.----...----..130......-------------.140----..----.......150-......------.160.-.----------.....170.....-..-180......-.190.......200..-----------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------------------------------------------------------------------------------------------LSNFTA--KV
P
L
S
E
R
M
A
D
V
L
----IS-K------DRWKDDE---E
G
Y
L
K
V
-KYG
L
E
I
I
L
I
N
V
M
K
F
A
L
V
Y
G
--
I
A
L
V
T
G
L
L
L
Q
T
-
V
T
V
H
L
S
Y
L
W
L
R
R
Y-SFGLHAT---KT
L
N
C
T
L
I
S
L
L
M
F
V
L
A
P
F
V
F
----------------Q-NIPSN
N
W
I
V
L
--G
T
F
-
G
F
-
I
L
--------
L
-----
N
----
M
F
L----FAPADTESLPL-------------I
G
------
E
E
----
H
R
K
T
L
K
R
K
A
M
-
I
G
T
L
I
L
------
T
G
I
A
L
-
L
----------
I
P
F
A
E
M
K
T
L
I
M
V
G
-
S
L
-
F
Q
V
I
SIN
P
L
-
T
Y
K
L
L
K
R
R
YRNYEKYE-----------------------------------------------------------------------------------------------------------------------------------
19
Fugue
76.46
17%
-94
- C7 -
4OO1
1
RRP4_YEAST
H:
[9-361]
-------------------------------------------I
T
I
T
K
R
N
GAFS
D
S
Q
I
V
T
PGELVTDDPI
W
M
R
G
H
G
T
Y
F
L
DN
M
T
Y
S
S
V
A
G
T
V
S
R
V
NR
L
L
S
V
I
P
L
--
K
G
R
Y
A
P
E
T
G
D
H
V
----
V
G
-
R
I
AEVGN
K
R
W
K
V
D
I
---
G
G
K
Q
H
A
-
V
L
M
L
G
S
V
N
L
P
G
Q
M
R
S
F
L
K
E
--
G
D
L
L
N
A
E
V
Q
S
L
-
F
Q
D
G
S
A
S
L
H
T
R
S
L
-
K
Y
G
K
L
R
N
---
G
M
F
C
Q
--
V
P
S
S
L
I
V
R
A
K
N
H
T
----------------
H
-
N
L
P
G
N
I
T
V
V
L
--
G
V
N
-
G
Y
-
I
W
--------
L
-----
R
----
K
T
S
----
Q
M
D
L
A
R
D
T
P
S
A
NSWQIYSDENDPS
I
S
------
N
N
----
I
R
Q
A
I
C
R
Y
A
N
-
V
I
K
A
L
A
F
C
EIGI
T
Q
Q
R
I
-
V
----------
S
A
Y
E
A
S
M
V
Y
S
N
V
G
-
E
L
-
I
E
K
N
V
M
E
S
I
-
G
S
D
I
L
T
A
E
K
M
R
G
N
--------------------------------------------------------------------------------------------------------------------------------------
27
Fugue
72.56
20%
-140
- C6 -
3L56
-
?
B:
[541-745]
------------------------------------------------------------------------------------------------------
G
P
--
E
S
V
L
V
N
T
Y
Q
W
I
I
R
N
W
E
T
V
-
K
------
I
Q
W
S
Q
D
P
---
T
M
L
Y
N
--
K
M
E
F
E
P
F
Q
S
L
V
P
K
A
A
R
G
Q
Y
--
S
G
F
V
R
T
L
F
Q
Q
M
-
R
D
V
L
G
T
F
D
-------------------
T
V
Q
I
I
K
L
L
P
F
A
A
A
P
P
K
Q
----------------
S
-
R
M
Q
F
S
S
L
T
V
N
V
R
G
S
G
-
M
R
-
I
L
--------
V
-----
R
GNSP
V
F
N
----
Y
N
K
A
-
T
K
R
L
T
V
-------------
L
G
------
K
D
A
G
A
L
T
E
D
P
D
E
G
T
A
G
-
V
E
S
A
V
L
------
R
G
F
L
I
-
L
GKEDKRYGPA
L
S
I
N
E
L
S
N
L
A
K
---
G
E
-
K
A
N
V
L
I
G
Q
G
-
D
V
V
L
V
M
K
R
K
R
D
S
S
I
L
T
-----------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
67.00
34%
-114
- C7 -
4PD5
2
?
A:
[304-382]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
G
W
L
F
A
P
L
A
F
----------------
L
I
G
V
P
W
N
E
A
T
V
A
--
G
E
F
I
G
L
K
T
V
--------
A
-----
N
----
E
F
V
A
Y
S
Q
F
A
P
Y
L
T
E
A
A
P
V
-------------
V
L
------
S
E
----
K
T
K
A
I
I
S
F
A
L
-
C
G
F
A
N
L
------
S
S
I
A
I
-
L
----------
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
66.31
34%
-114
- C7 -
4PB2
2
?
A:
[304-382]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
G
W
L
F
A
P
L
A
F
----------------
L
I
G
V
P
W
N
E
A
T
V
A
--
G
E
F
I
G
L
K
T
V
--------
A
-----
N
----
E
F
V
A
Y
S
Q
F
A
P
Y
L
T
E
A
A
P
V
-------------
V
L
------
S
E
----
K
T
K
A
I
I
S
F
A
L
-
C
G
F
A
N
L
------
S
S
I
A
I
-
L
----------
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
65.88
34%
-113
- C7 -
4PD8
2
?
A:
[304-382]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
G
W
L
F
A
P
L
A
F
----------------
L
I
G
V
P
W
N
E
A
T
V
A
--
G
E
F
I
G
L
K
T
V
--------
A
-----
N
----
E
F
V
A
Y
S
Q
F
A
P
Y
L
T
E
A
A
P
V
-------------
V
L
------
S
E
----
K
T
K
A
I
I
S
F
A
L
-
C
G
F
A
N
L
------
S
S
I
A
I
-
L
----------
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
65.58
22%
-118
- C3 -
4XNV
15
P2RY1_HUMAN (first)
A:
[38-382]
SFKCA
L
T
K
T
GF
Q
F
Y
Y
L
P
A
V
Y
I
L
V
F
I
I
G
F
L
G
N
S
V
A
I
W
M
F
V
FHMKPWS
G
I
S
V
Y
M
F
N
L
A
L
A
D
F
L
Y
V
L
T
L
P
A
L
I
F
Y
Y
F
N
KTDWIFG
D
A
M
C
K
L
Q
R
F
I
F
H
V
N
L
Y
G
S
I
L
F
L
--
T
C
I
S
A
H
R
Y
S
G
V
V
----
Y
P
-
K
------
S
L
G
R
L
K
K
---
K
N
A
I
C
I
-
S
V
L
V
W
L
I
V
V
V
A
I
S
P
I
L
F
Y
S
--
G
T
G
V
R
K
N
K
T
I
T
-
C
Y
D
T
T
S
D
E
Y
L
R
S
Y
F
I
Y
S
M
C
T
T
---
V
A
M
F
C
V
P
L
V
L
I
L
G
C
Y
G
L
I
V
R
----------------
A
-
L
I
Y
K
M
K
K
Y
T
C
--
T
V
C
-
G
Y
-
I
Y
N
PEDGDPD
N
-----
G
----
V
N
P
----
G
T
D
F
K
D
I
V
C
P
L
-------------
C
G
VGKDQ
F
E
E
----
V
E
E
P
L
R
R
K
S
I
Y
L
V
I
I
V
L
------
T
V
F
A
V
S
Y
----------
I
P
F
H
V
M
K
T
M
N
L
R
A
-
R
L
D
F
Q
----
T
P
A
-
M
C
A
F
N
D
R
V
Y
A
T
Y
Q
V
T
R
G
L
A
S
L
N
S
C
V
N
P
I
L
Y
F
LAGDTFRRR-----------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
65.47
34%
-108
- C7 -
4PD9
2
?
A:
[304-382]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
G
W
L
F
A
P
L
A
F
----------------
L
I
G
V
P
W
N
E
A
T
V
A
--
G
E
F
I
G
L
K
T
V
--------
A
-----
N
----
E
F
V
A
Y
S
Q
F
A
P
Y
L
T
E
A
A
P
V
-------------
V
L
------
S
E
----
K
T
K
A
I
I
S
F
A
L
-
C
G
F
A
N
L
------
S
S
I
A
I
-
L
----------
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
65.15
34%
-110
- C7 -
4PD7
2
?
A:
[304-382]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
G
W
L
F
A
P
L
A
F
----------------
L
I
G
V
P
W
N
E
A
T
V
A
--
G
E
F
I
G
L
K
T
V
--------
A
-----
N
----
E
F
V
A
Y
S
Q
F
A
P
Y
L
T
E
A
A
P
V
-------------
V
L
------
S
E
----
K
T
K
A
I
I
S
F
A
L
-
C
G
F
A
N
L
------
S
S
I
A
I
-
L
----------
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
65.10
34%
-115
- C7 -
4PD6
2
?
A:
[304-382]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
G
W
L
F
A
P
L
A
F
----------------
L
I
G
V
P
W
N
E
A
T
V
A
--
G
E
F
I
G
L
K
T
V
--------
A
-----
N
----
E
F
V
A
Y
S
Q
F
A
P
Y
L
T
E
A
A
P
V
-------------
V
L
------
S
E
----
K
T
K
A
I
I
S
F
A
L
-
C
G
F
A
N
L
------
S
S
I
A
I
-
L
----------
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
64.95
34%
-112
- C7 -
4PB1
2
?
A:
[304-382]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
G
W
L
F
A
P
L
A
F
----------------
L
I
G
V
P
W
N
E
A
T
V
A
--
G
E
F
I
G
L
K
T
V
--------
A
-----
N
----
E
F
V
A
Y
S
Q
F
A
P
Y
L
T
E
A
A
P
V
-------------
V
L
------
S
E
----
K
T
K
A
I
I
S
F
A
L
-
C
G
F
A
N
L
------
S
S
I
A
I
-
L
----------
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
64.92
34%
-114
- C7 -
4PDA
2
?
A:
[304-382]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
G
W
L
F
A
P
L
A
F
----------------
L
I
G
V
P
W
N
E
A
T
V
A
--
G
E
F
I
G
L
K
T
V
--------
A
-----
N
----
E
F
V
A
Y
S
Q
F
A
P
Y
L
T
E
A
A
P
V
-------------
V
L
------
S
E
----
K
T
K
A
I
I
S
F
A
L
-
C
G
F
A
N
L
------
S
S
I
A
I
-
L
----------
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
Fugue
64.61
16%
-133
- C4 -
4RFS
-
?
S:
[3-200]
---------------------------------------------------------------------------------------------------
R
H
K
T
F
--
R
L
V
V
D
A
L
L
M
A
I
V
----
L
L
-
Q
------
N
L
--
V
P
F
---
L
G
Y
I
P
F
G
P
F
S
M
T
L
I
G
L
T
V
I
V
A
G
S
A
L
G
PR
D
G
L
L
I
G
G
F
W
G
L
-
I
T
F
V
R
A
F
T
W
P
S
S
P
-
V
A
P
L
I
F
T
---
N
P
L
I
S
I
L
P
R
L
L
M
G
L
V
A
G
S
L
Y
----------------
L
-
W
G
R
H
R
Q
W
S
M
R
--
Q
A
M
-
Q
V
-
A
A
--------
G
-----
C
----
A
A
L
----
T
N
T
V
L
V
L
G
L
V
F
-------------
L
F
------
Y
Q
----
T
P
A
V
L
-
G
Y
V
L
-
M
I
S
L
F
T
------
N
G
I
P
E
-
L
----------
I
L
D
V
L
V
A
P
L
I
------------
A
M
P
L
-
R
R
Q
W
E
R
L
K
P
Q
-----------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
64.60
34%
-117
- C7 -
3TIJ
2
?
A:
[304-382]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
G
W
L
F
A
P
L
A
F
----------------
L
I
G
V
P
W
N
E
A
T
V
A
--
G
E
F
I
G
L
K
T
V
--------
A
-----
N
----
E
F
V
A
Y
S
Q
F
A
P
Y
L
T
E
A
A
P
V
-------------
V
L
------
S
E
----
K
T
K
A
I
I
S
F
A
L
-
C
G
F
A
N
L
------
S
S
I
A
I
-
L
----------
L
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
Fugue
60.60
20%
-102
- C7 -
4WGV
-
?
A:
[5-399]
-----------------------------------------------------VGYMD
P
G
N
W
I
T
S
M
Q
G
G
A
Q
YGYTL
L
F
V
I
L
I
S
S
L
A
A
M
L
L
Q
S
M
T
V
R
L
G
I
A
T
G
K
D
--
L
A
Q
M
T
R
H
F
L
S
K
P
----
V
A
-
I
------
I
F
W
I
I
A
E
---
L
A
I
I
A
T
-
D
I
A
--
E
V
I
G
S
A
I
A
L
D
L
I
F
G
--
I
P
L
I
V
G
A
L
I
----
T
V
F
D
V
F
L
L
L
F
I
M
-
R
F
G
F
R
K
I
---
E
A
I
V
G
T
L
I
F
T
V
L
A
I
F
V
F
E
V
F
ISSPQLTDILNGFVPH
K
-
E
I
V
T
N
Q
G
I
L
Y
--
I
A
L
-
G
I
-
I
G
--------
A
T
I
M
P
H
N
----
L
Y
L
----
H
S
S
I
V
Q
S
R
K
Y
----------------------
D
R
----
H
D
N
E
E
K
A
Q
A
I
-
K
Y
A
T
I
D
------
S
N
L
Q
L
-
S
----------
I
A
F
V
V
N
C
L
L
L
T
L
G
A
A
L
-
F
F
G
T
K
T
N
D
L
G
G
F
Y
D
L
Y
H
A
L
K
T
E
P
V
L
G
A
T
L
G
G
V
M
S
T
L
F
A
V
A
L
L
A
S
G
Q
N
S
T
I
T
G
T
L
A
G
Q
I
V
M
E
G
FLR
L
S
I
P
N
W
L
R
R
L
I
T
R
S
L
A
V
I
P
V
I
I
C
L
I
I
F
KGN
S
E
K
I
E
Q
L
L
V
F
S
Q
V
F
L
S
I
A
L
P
F
S
L
I
P
L
Q
L
A
T
S
N
KKLMGPFI
N
K
T
W
V
N
I
I
S
W
T
L
I
V
I
L
S
G
L
N
V
Y
25
Fugue
59.23
12%
-114
* C6 *
4ZJF
5
?
A:
[12-172]
--------------------------------------------------------------------------------------------------
T
L
N
M
T
M
--
P
L
S
C
T
K
N
N
S
H
H
Y
----
I
M
-
V
------
G
N
---------------
E
T
G
L
E
L
T
L
T
N
--
T
S
I
I
N
H
K
--
F
C
N
L
S
D
A
H
K
K
N
-
L
Y
D
H
A
L
M
S
I
I
S
T
F
-
H
L
S
I
P
N
F
NQY
E
A
M
S
C
D
F
N
G
G
K
I
S
V
Q
Y
N
L
S
H
----------------
S
-
Y
-
A
G
D
A
A
N
H
C
--
G
T
V
-
A
N
-
G
V
--------
L
-----
Q
----
T
F
M
----
R
M
A
---------------------
W
G
------
G
S
----
Y
I
A
L
D
S
G
R
--------------------------------------
G
N
W
D
C
I
M
-
T
S
-
Y
Q
Y
L
I
I
Q
N
T
-
T
W
E
----
D
H
C
Q
F
S
R
P
S
-----------------------------------------------------------------------------------------------------------------------------------
24
Fugue
53.78
10%
-98
- C5 -
1QRE
2
CAH_METTE
A:
[38-247]
----------------------------------------------------------------------------------------------T
V
D
E
F
S
N
I
R
E
N
P
V
T
P
W
N
P
E
P
S
A
P
V
----
I
D
-
P
------
T
A
Y
I
D
P
Q
A
S
V
I
G
E
V
T
I
-
G
A
N
V
M
V
S
P
M
A
S
I
R
S
D
E
G
M
P
--
I
F
V
G
D
R
S
N
V
Q
D
G
V
V
L
H
A
L
E
T
I
N
E
E
G
-
E
P
I
E
D
N
I
---
V
E
V
D
------------------------------------
G
K
E
Y
A
V
Y
I
--
G
N
N
-
V
S
-
L
A
--------
H
-----
Q
----
S
Q
V
----
H
G
P
A
A
V
G
D
D
T
F
-------------
I
G
------
M
Q
A
F
V
-
F
K
S
K
V
G
N
N
C
V
-
L
E
P
R
S
A
------
A
I
G
V
T
-
I
----------
P
D
G
R
Y
I
P
A
G
M
V
V
T
-
S
Q
-
A
E
A
D
K
L
P
E
V
-
T
D
D
Y
A
Y
S
H
T
N
E
A
V
V
Y
V
N
V
H
L
A
E
G
Y
K
E
T
S-----------------------------------------------------------------------------------------------------------------------
22
Fugue
35.02
21%
192
- C7 -
2MES
-
DLG4_HUMAN
B:
[1-19]
--------------------------------------------------------------------------------------------------------------
M
D
C
L
C
I
V
T
----
T
K
-
K
------
Y
R
Y
Q
D
E
D
---
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
Fugue
30.43
28%
174
* C7 *
3W1S
-
ATG16_YEAST
B:
[25-49]
---------------------------------------------------------------------------------------------------------------
D
S
M
D
D
L
L
----
I
R
-
R
------
L
T
D
R
N
D
K
---
E
A
H
L
N
E
-
L
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
27.33
14%
130
- C7 -
3E0Z
-
?
A:
[71-99]
---------------------------------------------------------------------------------------------------------------
K
Y
L
I
H
L
L
----
G
N
Y
E
------
P
D
D
T
H
D
E
---
Q
T
V
E
L
F
-
H
M
G
E
T
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
24.66
38%
451
- C7 -
3LQV
-
SF3B1_HUMAN
P:
[17-29]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
E
R
N
R
P
L
-------------
S
D
------
E
E
----
L
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------