@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0050: (2016-03-11 )
MFSILMAIIQITGIFIAIQILTNKVFSIKEGLVTIAIAMLAFPLFTLVQYWSMIFVLIVFVSALYWKNKNVVVSASITLVVIILLTISDSIVGFILVPGLNFKYDEIFNELLPTLIYCAGMLANLLVFSFLLRKLIEKVNISRFVEHRKYAYIIFSIVALTVLAFYMNIYAGSIAGFDGSVLKINTLIFTGYTILLIVIVTVVINTATNELKVQNQKEQLEQLQDYVTTLESLHREMRVFRHDYVNILSTLVGYIDNNDMPGLKYYFENNIVPINKTIESNNYKISLLQNIHVIELKGLLAVKLIRAQELKIDAILEVVEPIDKISMDSIDLCKVVGILLDNAVEAALTCENPVIRIAFVKKGDSIIIVFANSLPVNMPPIYKIFEEGFSTKGEGRGLGLASLREIMKKYSHVALDTKVTDREVIQELEIM
Atome Classification :
(20 SA)
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10........20........30....--....40....----....50........60........70....--....80........90........100.......--110.......120.......130.......140.......150.......160-----........170.......180.......190.....-----..200.......210.......220.......230.......240.......250..-....------------.260.......270.-......280.......290-------------.----------------......-------300.....-----..310-------........320-.......330-........340-.........350---------.-.......360---------........370....-...380----------------------.-----..---.....--.390-----.-----.......400......-.410.......---420.........430------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
F
S
I
L
M
A
I
I
Q
I
T
G
I
F
I
A
I
Q
I
L
TN
K
V
F
S
I
K
E
G
L
V
T
I
--
A
I
A
M
L
A
F
P
L
F
----
T
L
V
Q
Y
W
S
M
I
F
V
L
I
V
F
V
S
A
L
YWKNK
N
V
V
V
S
A
--
S
I
T
L
V
V
I
I
L
L
TISD
S
I
V
G
F
I
L
VPGLNF
K
Y
D
E
I
F
N
--
E
L
L
P
T
L
I
Y
C
A
G
M
L
A
N
L
L
V
F
S
F
L
L
R
K
L
I
E
KV
N
I
S
R
F
V
E
HRK
Y
A
Y
I
I
F
S
I
V
A
L
T
------
V
L
A
F
Y
M
N
I
YAGSIAGFDG
S
V
L
K
I
N
T
L
I
FT
G
Y
T
I
L
L
I
-----
V
I
V
T
V
V
I
NTATN
E
L
K
VQ
N
Q
K
E
Q
L
E
Q
L
Q
D
Y
V
T
T
L
E
S
L
H
R
E
M
R
V
F
R
H
D
Y
V
N
I
L
S
T
L
V
G
Y
-IDNN------------DMPG
L
K
Y
Y
FENN
I
V
P
-IN
K
T
IESN
N
Y
K
I
S
L
L
Q
N
I
H
-------------
V
----------------
I
E
LK
G
L
-------
L
A
V
K
L
I
R
A-----QE
L
K
--------
I
D
A
I
L
E
V
V
E
P
I
-
D
K
ISMD
S
I
D
--
L
C
K
V
V
G
I
L
L
---
D
N
A
V
E
A
A
LTCE----------N-
P
V
I
R
I
A
F
V
K----------KG
D
S
I
I
I
V
FANSLPV-NM
P
P
------------------------
I
-----
Y
K
---
I
F
E
EG--FST------K-----GEGRGL
G
L
A
S
L
R
E
I
M
K
-
K
YSHVALDTKV---T--
D
R
E
V
I
Q
E
LEIM-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
86.28
37%
-127
- C3 -
4BXI
5
?
A:
[1-153]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
A
I
K
L
N
G
I
E
N
L
K
-------------
V
----------------
R
E
I
K
G
L
-------
I
T
A
K
I
L
R
A
-----
Q
E
M
N
--------
I
P
I
S
I
E
I
P
D
E
V
-
S
S
I
N
L
N
M
I
D
--
L
S
R
S
I
G
I
I
L
---
D
N
A
I
E
A
S
T
E
I
D
----------
D
-
P
I
I
R
V
A
F
I
E
----------
S
E
N
S
V
T
F
I
V
M
N
K
C
A
D
-
D
I
P
R
------------------------
I
-----
H
E
---
L
F
Q
E
S
--
F
S
------------------
L
G
L
S
T
L
K
E
I
A
D
-
N
A
D
N
V
L
L
D
T
I
I
---
E
--
N
G
F
F
I
Q
K
V
E
I
I
N
N-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
86.15
40%
-126
- C3 -
4BXI
5
?
A:
[1-151]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
A
I
K
L
N
G
I
E
N
L
K
-------------
V
----------------
R
E
I
K
G
L
-------
I
T
A
K
I
L
R
A
-----
Q
E
M
N
--------
I
P
I
S
I
E
I
P
D
E
V
-
S
S
I
N
L
N
M
I
D
--
L
S
R
S
I
G
I
I
L
---
D
N
A
I
E
A
S
T
E
I
D
----------
D
-
P
I
I
R
V
A
F
I
E
----------
S
E
N
S
V
T
F
I
V
M
N
K
C
A
D
-
D
I
P
R
------------------------
I
-----
H
E
---
L
F
Q
E
S
--
F
S
------------------
L
G
L
S
T
L
K
E
I
A
D
-
N
A
D
N
V
L
L
D
T
I
I
---
E
--
N
G
F
F
I
Q
K
V
E
I
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
Fugue
71.31
17%
-121
* C2 *
3W3W
1
IMB3_YEAST
A:
[3-1077]
ALP
E
E
V
N
R
T
L
L
Q
I
V
Q
A
FASD
N
Q
I
R
S
V
A
E
K
A
L
S
EEWITENN
I
E
Y
L
L
T
F
L
A
E
Q
A
A
FSQD
T
T
V
A
A
L
S
A
V
L
F
R
K
L
A
L
K
A
PITHIR
K
E
V
L
A
Q
I
R
S
S
L
L
K
G
F
L
SERA
D
S
I
R
H
K
L
S
D
A
I
A
E
C
VQDDLPAW
P
E
L
L
Q
A
L
I
E
S
L
K
SGN
P
N
F
R
E
S
S
F
R
I
L
T
T
V
P
Y
L
I
T
A
VD
I
N
S
I
L
P
I
F
Q
S
G
F
T
DAS
D
N
V
K
I
A
A
V
T
A
F
V
G
Y
F
K
Q
LPKSEWSKLGIL
L
P
S
L
L
N
S
L
P
R
F
L
D
D
GK
D
D
A
L
A
S
V
F
E
S
L
I
E
L
V
E
L
APKLFKDM
F
D
Q
I
I
Q
F
T
D
M
V
I
K
NKDLEP
P
A
R
T
T
A
L
E
L
L
T
V
F
S
E
N
A
P
Q
M
C
K
S
N
Q
N
Y
G
Q
T
L
V
M
V
T
L
I
M
M
T
EVSIDDDDA
A
E
W
I
E
SDDTDDEEE
V
T
Y
D
H
A
R
Q
A
L
D
R
V
A
L
K
LGGEYL
A
A
P
L
F
Q
Y
L
Q
Q
M
I
T
STE
W
R
E
R
F
A
A
M
M
A
L
S
S
A
AEGCA
D
V
L
I
G
E
I
P
K
I
L
D
M
V
I
P
L
I
NDPH
P
R
V
Q
Y
G
C
C
N
V
L
G
Q
I
S
T
D
F
S
P
F
I
Q
R
T
A
H
D
R
I
L
P
A
L
I
S
K
L
T
S
E
C
T
S
R
V
Q
T
H
A
A
A
A
L
V
N
F
S
E
F
A---
S
K
D
I
L
E
P
Y
L
D
S
L
L
T
N
L
L
V
L
L
Q
S
N
K
L
Y
V
Q
E
Q
--
A
L
T
T
I
A
F
I
A
E
A
A
K
---------
N
K
F
I
K
Y
Y
D
T
L
M
P
--
L
L
L
N
V
L
K
V
N
S
V
L
K
G
K
C
M
E
C
A
T
L
I
G
F
A
V
---
G
K
E
K
F
H
E
H
S
Q
E
L
I
S
I
L
V
A
L
Q
N
S
---------------
D
A
L
R
S
Y
L
E
Q
S
W
S
R
I
C
R
I
L
G
D
D
F
V
P
L
L
P
-----
I
V
I
P
P
L
L
I
T
A
K
A
T
Q
D
---------------------------------------
V
G
L
-
I
E
E
E
------------
E
A
A
N
F
Q
Q
Y
P
D
W
D
V
V
Q
-
V
Q
G
-------
K
H
I
A
I
H
T
S
V
-------------
L
----------------
D
D
K
V
S
A
-------
M
E
L
L
Q
S
Y
A
-----
T
L
L
R
--------
G
Q
F
A
V
Y
V
K
E
V
M
-
E
E
I
A
L
P
S
L
D
FY
L
H
D
G
V
R
A
A
G
---
A
T
L
I
P
I
L
L
S
C
L
----------
L
A
A
E
E
L
V
L
L
W
H
----------
K
A
S
S
K
L
I
G
G
L
M
S
E
P
---
M
P
E
------------------------
I
-----
T
Q
---
V
Y
H
N
S
--
L
V
N
------
G
-----
I
K
V
M
G
D
N
C
L
S
-
E
D
Q
L
A
-
A
F
T
K
G
V
S
A
N
L
T
---
D
--
T
Y
E
R
M
Q
D
R
D
E
Y
NED
F
T
D
E
D
L
L
D
E
I
N
K
S
I
A
A
V
L
K
T
T
N
GHY
L
K
N
L
E
N
I
W
P
M
I
N
T
F
L
LE
P
I
L
V
I
F
A
L
V
V
I
G
D
L
I
Q
YEQTASMKNAF
I
P
K
V
T
E
C
L
ISPD
A
R
I
R
Q
A
A
S
Y
I
I
G
V
C
A
Q
YAPSTYADVCIPT
L
D
T
L
V
Q
I
V
DGSKLEEN
R
S
S
T
E
N
A
S
A
A
I
A
K
I
L
Y
A
Y
NSNIPD
T
Y
T
A
N
W
F
K
T
LPTITD
K
E
A
A
S
F
N
Y
Q
F
L
S
QVCAQSN
I
S
A
V
V
D
S
V
I
Q
A
L
N
E
RSLT
V
I
S
S
V
K
K
L
L
G
F
L
P
S
S
D
A
M
A
I
F
N
RYP
A
D
I
M
E
K
V
H
K
W
F
31
HHSearch
68.60
22%
-59
- C3 -
3A0R
1
?
A:
[128-344]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
L
S
I
L
G
E
M
T
A
R
V
A
H
E
I
R
N
P
I
T
I
I
G
G
F
-
I
M
R
M
KKHLD-------
D
P
E
T
L
K
K
Y
I
N
I
I
T
-
N
-
E
L
S
R
L
E
T
I
V
K
E
I
L
E
Y
S
K
E
R
V
L
E
F
T
E
F
N
L
----
N
----------------
E
L
I
R
E
V
-------
Y
V
L
F
E
E
K
I
-----
R
K
M
N
--------
I
D
F
C
F
E
T
D
N
E
D
-
L
R
V
E
A
D
R
T
R
--
I
K
Q
V
L
I
N
L
V
---
Q
N
A
I
E
A
T
G
E
------------
N
-
G
K
I
K
I
T
S
E
D
----------
M
Y
T
K
V
R
V
S
V
W
N
S
G
P
P
I
P
E
E
L
------------------------
K
-----
E
K
---
I
F
S
P
F
--
F
T
T
-----------------
L
G
L
S
I
C
R
K
I
I
E
D
E
H
G
G
-
K
I
W
T
E
N
RE-
N
--
G
V
V
F
I
F
E
I
P
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
HHSearch
68.33
24%
-83
* C3 *
3A0Y
-
?
A:
[616-750]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
E
V
-------
Y
V
L
F
E
E
K
I
-----
R
K
M
N
--------
I
D
F
C
F
E
T
D
N
E
D
-
L
R
V
E
A
D
R
T
R
--
I
K
Q
V
L
I
N
L
V
---
Q
N
A
I
E
A
T
G
E
------------
N
-
G
K
I
K
I
T
S
E
D
----------
M
Y
T
K
V
R
V
S
V
W
N
S
G
P
P
I
P
E
E
L
------------------------
K
-----
E
K
---
I
F
S
P
F
--
F
T
T
------
K
-------
G
T
G
L
G
L
S
I
C
R
K
I
I
E
D
E
H
G
G
-
K
I
W
T
E
N
---
R
EN
G
V
V
F
I
F
E
I
P
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
66.06
31%
-86
- C3 -
3A0Y
-
?
A:
[627-726]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
K
M
N
--------
I
D
F
C
F
E
T
D
N
E
D
-
L
R
V
E
A
D
R
T
R
--
I
K
Q
V
L
I
N
L
V
---
Q
N
A
I
E
A
--
T
G
E
----------
N
-
G
K
I
K
I
T
S
E
D
----------
M
Y
T
K
V
R
V
S
V
W
N
S
-----
G
P
P
------------------------
I
PEELK
E
K
---
I
F
S
P
F
--
F
T
T
------
K
-------
G
T
G
L
G
L
S
I
C
R
K
I
I
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
HHSearch
65.03
16%
-79
- C3 -
2C2A
2
?
A:
[18-247]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
M
K
T
E
F
I
A
N
I
S
H
E
L
R
T
P
L
T
A
I
K
A
Y
-
A
E
T
I
Y
N
S
LGEL-----
D
L
S
T
L
K
E
F
L
E
V
I
I
D
--
Q
S
N
H
L
E
N
L
L
N
E
L
L
D
F
S
R
L
E
R
KS
L
Q
I
N
R
E
KVD
L
C
----------------
D
L
V
E
S
A
-------
V
N
A
I
K
E
F
A
-----
S
S
H
N
--------
V
N
V
L
F
E
S
N
V
P
C
P
V
E
A
Y
I
D
P
T
R
--
I
R
Q
V
L
L
N
L
L
---
N
N
G
V
K
Y
S
K
K
D
A
P---------
D
-
K
Y
V
K
V
I
L
D
E
----------
K
D
G
G
V
L
I
I
V
E
D
N
G
I
G
I
P
D
H
A
------------------------
K
-----
D
R
---
I
F
E
Q
F
--
Y
R
V
------
D
--------
T
G
L
G
L
A
I
T
K
E
I
V
E
-
L
H
G
G
-
R
I
W
V
E
S
E
V
G
K
--
G
S
R
F
F
V
W
I
P
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
HHSearch
64.47
21%
-81
- C3 -
1ID0
2
A:
[12-144]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
L
-------
T
S
A
L
N
K
V
Y
-----
Q
R
K
G
--------
V
N
I
S
L
D
I
S
P
E
--
I
S
F
V
G
E
Q
N
D
--
F
V
E
V
M
G
N
V
L
---
D
N
A
C
K
Y
C
L
E
---------------
F
V
E
I
S
A
R
Q
----------
T
D
E
H
L
Y
I
V
V
E
D
D
G
P
G
I
P
L
S
K
------------------------
R
-----
E
V
---
I
F
D
R
G
--
Q
R
V
------
D
TL---
R
P
G
Q
G
V
G
L
A
V
A
R
E
I
T
E
-
Q
Y
E
G
-
K
I
V
A
G
E
S
ML
G
--
G
A
R
M
E
V
I
F
G
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
63.44
31%
-78
- C3 -
3A0X
-
?
A:
[627-726]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
K
M
N
--------
I
D
F
C
F
E
T
D
N
E
D
-
L
R
V
E
A
D
R
T
R
--
I
K
Q
V
L
I
N
L
V
---
Q
N
A
I
E
A
--
T
G
E
----------
N
-
G
K
I
K
I
T
S
E
D
----------
M
Y
T
K
V
R
V
S
V
W
N
S
-----
G
P
P
------------------------
I
PEELK
E
K
---
I
F
S
P
F
--
F
T
T
------
K
-----
T
Q
G
T
G
L
G
L
S
I
C
R
K
I
I
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
63.15
31%
-67
- C3 -
3A0T
2
?
A:
[24-123]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
K
M
N
--------
I
D
F
C
F
E
T
D
N
E
D
-
L
R
V
E
A
D
R
T
R
--
I
K
Q
V
L
I
N
L
V
---
Q
N
A
I
E
A
--
T
G
E
----------
N
-
G
K
I
K
I
T
S
E
D
----------
M
Y
T
K
V
R
V
S
V
W
N
S
-----
G
P
P
------------------------
I
P
EELK
E
K
---
I
F
S
P
F
--
F
T
T
------
K
-----
T
Q
G
T
G
L
G
L
S
I
C
R
K
I
I
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
61.65
31%
-74
- C3 -
3A0W
4
?
A:
[24-123]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
K
M
N
--------
I
D
F
C
F
E
T
D
N
E
D
-
L
R
V
E
A
D
R
T
R
--
I
K
Q
V
L
I
N
L
V
---
Q
N
A
I
E
A
--
T
G
E
----------
N
-
G
K
I
K
I
T
S
E
D
----------
M
Y
T
K
V
R
V
S
V
W
N
S
-----
G
P
P
------------------------
I
PEEL
K
E
K
---
I
F
S
P
F
--
F
T
T
------
K
-----
T
Q
G
T
G
L
G
L
S
I
C
R
K
I
I
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
61.09
31%
-93
- C3 -
3A0Z
-
?
A:
[627-726]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
K
M
N
--------
I
D
F
C
F
E
T
D
N
E
D
-
L
R
V
E
A
D
R
T
R
--
I
K
Q
V
L
I
N
L
V
---
Q
N
A
I
E
A
--
T
G
E
----------
N
-
G
K
I
K
I
T
S
E
D
----------
M
Y
T
K
V
R
V
S
V
W
N
S
-----
G
P
P
------------------------
I
PEEL
K
E
K
---
I
F
S
P
F
--
F
T
----------------
T
G
L
G
L
S
I
C
R
K
I
I
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
61.02
15%
-98
- C2 -
4XMM
-
NUP85_YEAST
D:
[18-715]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ILVPMTVNDQPIEKNGDKMP
L
K
F
K
L
G
PLSY
Q
N
M
A
F
I
TAKDKY
K
L
Y
P
V
R
IPRLDTS
K
E
F
S
A
Y
V
S
G
L
F
E
I
Y
R
D
LGDDRVFNVV
N
S
N
F
A
K
E
H
N
A
T
V
N
L
A
M
E
A
I
L
N
E
L
E
V
F
I
G
R
V
K
D
Q
D
G
R
V
N
R
F
Y
E
L
E
E
S
L
T
V
L
--
N
C
L
R
T
M
Y
F
I
L
DGQD
V
E
E
N
R
S
E
F
I
E
S
L
L
N
W
I
N
R
S
D
G
E
P
D
E
E
Y
I
E
Q
VF
S
V
A
G
K
K
V
F
E
T
Q
Y
F
W
K
L
L
N
Q
L
V
L
R
G
L
L
S
Q
A
I
G
C
I
E
R
S
D
L
L
P
Y
L
S
D
T
C
A
V
S
F
D
A
V
S
D
S
I
E
L
L
K
Q
Y
P
K
D
S
S
S
T
F
R
E
W
K
N
L
V
L
K
L
S
Q
A
F
G
S
S
ATDIS
G
E
L
R
D
Y
I
E
D
F
L
L
V
I
G
G
N
Q
R
K
I
L
Q
Y
S
R
T
W
Y
E
S
F
C
G
F
L
L
YYIPS
L
E
L
S
A
E
Y
L
Q
M
S
L
E
A
N
V
V
D
I
T
N
D
W
E
Q
P
C
V
D
I
I
S
-
G
K
I
H
S
I
L
P
V
M
E
S
L
D
S
C
T
A
A
F
T
A
M
I
-
C
E
A
K
------------
G
L
I
------
E
N
I
F
E
G
-
L
E
D
L
F
S
Y
R
N
G
M
A
S
Y
M
L
N
S
F
-------------
A
----------------
F
E
L
C
S
L
GDKEL
W
P
V
A
I
G
L
I
A
L
SATGT
R
S
A
K
--------
K
M
V
I
A
E
L
L
P
H
Y
-
P
F
V
T
N
D
D
I
E
--
W
M
L
S
I
C
V
E
W
RL
P
E
I
A
K
E
I
Y
T
T
L
G
----------
N
-
I
E
S
I
A
N
F
S
L
----------
V
K
S
Y
S
W
L
L
F
E
A
S
C
M
E
-
G
Q
K
V
------------------------
L
-----
N
A
---
I
V
S
K
D
--
D
V
I
------
I
-----
P
Q
D
I
-
L
V
T
N
S
M
R
Q
T
L
A
-
P
Y
A
V
L
S
Q
F
Y
D
R
---
E
--
D
W
G
Q
A
L
R
L
L
L
L
L
I
E
FH
Y
L
V
L
L
V
A
K
F
L
Y
P
I
FE
D
S
V
A
T
V
I
E
V
I
E
T
K
WS
N
L
Y
E
T
I
I
E
A
D
K
SA
T
L
L
K
N
L
R
K
K
L
N
F
K
L
C
Q
A
F
M------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
59.44
31%
-91
- C3 -
3A0W
3
?
B:
[24-123]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
K
M
N
--------
I
D
F
C
F
E
T
D
N
E
D
-
L
R
V
E
A
D
R
T
R
--
I
K
Q
V
L
I
N
L
V
---
Q
N
A
I
E
A
--
T
G
E
----------
N
-
G
K
I
K
I
T
S
E
D
----------
M
Y
T
K
V
R
V
S
V
W
N
S
-----
G
P
P
------------------------
I
PEELK
E
K
---
I
F
S
P
F
--
F
T
T
-----------------
L
G
L
S
I
C
R
K
I
I
E
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47
HHSearch
59.40
15%
-62
- C3 -
1I58
3
CHEA_THEMA
A:
[18-188]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
R
D
L
A
-----
K
K
M
N
--------
K
E
V
N
F
I
M
R
G
E
D
T
E
L
D
R
T
F
V
E
E
--
I
G
E
P
L
L
H
L
L
---
R
N
A
I
D
H
G
I
E
P
K
E
E
R
I
A
K
GKPP
I
-
G
T
L
I
L
S
A
R
H
----------
E
G
N
N
V
V
I
E
V
E
D
D
G
R
G
I
D
K
E
K
I
I
R
K
A
I
E
K
GLID
E
S
K
A
A
T
LS
D
Q
E
I
L
-----
N
F
---
L
F
V
P
G
--
F
S
T
------
K
E
K
V
S
E
V
S
G
R
G
V
G
M
D
V
V
K
N
V
V
E
-
S
L
N
G
-
S
I
S
I
E
S
E
KD
K
--
G
T
K
V
T
I
R
L
P
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
57.56
31%
-60
- C3 -
1ID0
2
A:
[44-123]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
--
F
V
E
V
M
G
N
V
L
---
D
N
A
C
K
Y
C
L
E
---------------
F
V
E
I
S
A
R
Q
----------
T
D
E
H
L
Y
I
V
V
E
D
D
G
P
---
G
I
P
------------------------
L
-----
S
K
REV
I
F
D
R
G
QR
V
D
T
------
L
-----
R
P
G
Q
G
V
G
L
A
V
A
R
E
I
T
E
-
Q
Y
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
57.01
13%
-125
- C1 -
1TGO
-
DPOL_THEGO
A:
[1-347]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
I
L
D
T
D
Y
I
T
E
D
G
K
P
V
I
R
I
F
K
K
E
-----
N
G
E
F
K
I
--
D
Y
D
R
N
F
E
P
Y
I
----
Y
A
L
L
K
D
D
S
A
I
E
D
V
K
K
I
T
A
E
R
H
G
-----
T
T
V
--
R
V
V
R
A
E
K
V
K
K
K
F
L
G
R
P
I
E
V
W
K
L
Y
F
T
H
P
Q
D
V
P
A
I
R
--
D
K
I
K
E
H
P
A
V
V
D
I
Y
E
Y
D
I
P
---
F
A
K
R
Y
L
I
D
K
G
L
I
P
M
E
G
D
E
E
L
K
M
L
A
F
D
I
E
T
L
Y
---------------
H
E
G
E
E
F
A
E
G
P
I
L
M
I
S
Y
A
D
E
E
G
A
R
V
I
T
W
-----
K
N
I
---------------
D
L
P
Y
V
D
V
V
S
T
E
K
E
M
I
K
R
F
L
K
V
V
K
E
K
D
P
D
------
V
L
I
T
Y
N
G
D
N
F
------------
D
F
A
Y
L
K
K
R
S
E
K
L
G
V
K
-
F
I
L
G
R
E
G
S
E
P
K
I
Q
R
M
G
D
R
F
-------------
A
----------------
V
E
V
K
G
R
-------
I
H
F
D
L
Y
P
V
-----
I
R
R
T
--------
I
--------------
N
L
P
T
Y
T
--
L
E
A
V
Y
E
A
I
F
---
G
Q
P
K
E
-----
K
----------
V
-
Y
A
E
E
I
A
Q
A
W
----------
E
T
G
E
G
L
E
R
V
A
R
Y
S
M
E
-
D
A
K
V
------------------------
T
-----
Y
E
---
L
G
K
E
F
--
F
P
M
------
E
-----
A
Q
L
S
R
L
V
G
Q
S
L
W
D
V
S
R
-
S
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
44
HHSearch
56.26
18%
-71
- C3 -
1R62
-
NTRB_ECOLI
A:
[217-347]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
--------
V
R
L
I
R
D
Y
D
P
S
L
-
P
E
L
A
H
D
P
D
Q
--
I
E
Q
V
L
L
N
I
V
---
R
N
A
L
Q
A
L
G
P
E
-----------
G
-
G
E
I
I
L
R
T
R
T
A
F
QLTLHGER
Y
R
L
A
A
R
I
D
V
E
D
N
G
P
G
I-----------------------------------------------------------------
G
L
G
L
S
I
A
R
N
L
I
D
-
Q
H
S
G
-
K
I
E
F
T
S
W
P-
G
--
H
T
E
F
S
V
Y
L
P
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
HHSearch
54.38
14%
-50
- C3 -
2E0A
2
PDK4_HUMAN
A:
[90-349]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
D
D
Q
K
A
L
S
D
F
V
D
T
L
I
K
V
R
N
R
H
H
N
V
V
P
T
M
-
A
Q
G
I
I
E
Y
K
D
A
C
T
V
D
PV
T
N
Q
N
L
Q
Y
F
L
D
R
F
Y
M
N
R
I
S
T
R
M
L
-
M
N
Q
H
I
L
I
F
S
D
S
Q
-------------
T
GNPSHIGSIDPNCD
V
V
A
V
V
Q
D
A
-------
F
E
C
S
R
M
L
C
-----
D
Q
Y
Y
L
S
S
P
E
L
K
L
T
Q
V
N
G
K
F
P
D
Q
P
-
I
H
I
V
Y
V
P
S
H
--
L
H
H
M
L
F
E
L
F
---
K
N
A
M
R
A
T
V
E
H
Q
E
NQP
S
-----
L
-
T
P
I
E
V
I
V
V
L
----------
G
K
E
D
L
T
I
K
I
S
D
R
G
G
G
V
P
L
R
I
------------------------
I
-----
D
R
---
L
F
S
Y
T
--
Y
S
T
APTPNA
P
-----
L
A
G
F
G
Y
G
L
P
I
S
R
L
Y
A
K
-
Y
F
Q
G
-
D
L
N
L
Y
S
LSG
Y
--
G
T
D
A
I
I
Y
L
K
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
54.30
31%
-62
- C3 -
3A0R
1
?
A:
[221-320]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
K
M
N
--------
I
D
F
C
F
E
T
D
N
E
D
-
L
R
V
E
A
D
R
T
R
--
I
K
Q
V
L
I
N
L
V
---
Q
N
A
I
E
A
--
T
G
E
----------
N
-
G
K
I
K
I
T
S
E
D
----------
M
Y
T
K
V
R
V
S
V
W
N
S
-----
G
P
P
------------------------
I
PEELK
E
K
---
I
F
S
P
F
--
F
T
T
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L
G
L
S
I
C
R
K
I
I
E
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