@TOME V2.3
(Nov 2016)

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Alignment:

3D Common Core:

Structural Clustering:

Modeller Result :

Complexes Modeling
Templates Information:
Sequence & Result Tab:

Values color: [ Good | Correct | Middling | Bad ]Sequence color : MutatedHelixStrandConserved

Query sequence : Lmo0052: (2016-03-11 )
MSGYFQKRMLKYPLYGLIAATIILSVITFFFSWWLSALVVVGGIILTVAMFYFEYRLNEDVQLYVSNLTYRIKRSEEEALVEMPMGILLYDEHYKIEWVNPFMSKYFDKAELIGESLEEVGPEFLDVITGNDEKGIMSIAWRDHRFDTIVKRKERILYLYDRTEYYDLNKKFQANKSVFAVIFLDNYDEWAQGMDDRRRSALNNLVTSMLTNWAREHRIYLKRISTDRFMAFLTEEMLKRLEEEKFQILDRIRERTSKQNIPLTLSIGIGYKEDDLIQLADLAQSSLDLALGRGGDQVVIKQPEGKVRFYGGKTNPMEKRTRVRARVISQALQELITQSDQVFVMGHRYPDMDVIGSSLGVMRIAEMNDRNAYVVVEPGKMSPDVKRLMNEIEEYPNVIKNIVTPQVALENITEKSLLVVVDTHKPSMVINKELLDSATNVVVVDHHRRSEEFVGSPVLVYIEPYASSTAELITELFEYQPDLEQVGKIEATALLSGIVVDTKNFTLRTGSRTFDAASYLRSLGADTILVQQFLKEDITTFTQRSRLVESLEIYHDGMAIATGHEDEEFGTVIAAQAADTMLSMEGVQASFVITLRPDKLIGISARSLGQINVQVIMEKLGGGGHLSNAATQLKDVTIAEAEKQLISAIDAYWKGET

Atome Classification :

(20 SA) .........10........20........30........40........50........60........70........80........90..-......100.......110.......120.......130.......140.......150.......160.......170.......180...----....190.......200.......210.......220.......230.......-240.......250....--...260.......270.------......280.......290.......300.......310.......320.......330......----.340.......350......-.360-------.....--...370---------.....-...----.-----380......--.--390-.......400.....-------..410----........420.......430-----....----...440.......450...----....460....-------....470.....-------------..--480------..--.....490..-.....500.....-..510-----------.-------------......-520--------------------..-----------..--.-...----530..-.--.--...---------------.540.-....----.----.550..---.---.------...560..-.---...---.---570.......580.......590----..-.....--.--.600.......610.-......-----620.......630...-....640.......650.....
(Atome) (Ident) (Tito) (Num) (Ligand) (Uniprot) MSGYFQKRMLKYPLYGLIAATIILSVITFFFSWWLSALVVVGGIILTVAMFYFEYRLNEDVQLYVSNLTYRIKRSEEEALVEMPMGILLYDEH-YKIEWVNPFMSKYFDKAELIGESLEEVGPEFLDVITGNDEKGIMSIAWRDHRFDTIVKRKERILYLYDRTEYYDLNKKFQANKSVFAVIFLD----NYDEWAQGMDDRRRSALNNLVTSMLTNWAREHRIYLKRISTDRFMAFLTEEMLK-RLEEEKFQILDRIRERT--SKQNIPLTLSIGIGYKE------DDLIQLADLAQSSLDLALGRGGDQVVIKQPEGKVRFYGGKTNPMEKRTRVRARVISQALQELITQ----SDQVFVMGHRYPDMDVIGSS-LGV--------MRIAE--MNDR-----------NAYVV-VEP----G-----KMSPDVKRL--M--NEI-EEYPNVIKNIVTPQV-------ALEN-----ITEKSLLVVVDTHKPSMVINK-----ELLD----SATNVVVVDHHRRSEEFVG----SPVLVY-IEPY-------ASSTAELITELF-------------EY--QPD------LE--QVGKIEATAL-LSGIVVDTKNFTL-RTGSR-----------T-------------FDAASY-LR---------------------SL-----------GA--D-TIL----VQ-QF-L--K--EDI---------------TTFTQ-RSRL----V----ESLEIY---H---D------GMAIATGH-E---DEE---F---GTVIAAQAADTMLSMEGVQAS------FV-ITLRP--D--KLIGISARSLGQINV-QVIMEK-----LGGGGHLSNAATQLKD-VTIAEAEKQLISAIDAYWKGET
1 PsiBlast_PDB 94.1125% -74 - C2 -3W5W ? A:[4-337] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KVIAQAHIDHFTKWFERADKIVIVSHVSPDGDAIGSS-LGL--------YHFLD--SQDK-----------IVNVI-V-P----N-----AF-PDFLKW--M--PGS-KD---ILLYDRYQEF-------ADKL-----IMEADVICCLDFNALKRI--D-----EMSDIVAASPGRKIMIDHHLYPEDFCR-------ITI-SHPE-------ISSTSELVFRLI-------------CR--MGY------FS--DISKEGAECI-YTGMMTDTGGFTY-NSNNRE----------I-------------YFIISE-LL---------------------SK-----------GI--D-----------------K--DDIYRKVY----------NTYSESRLRLMGYVL----SNMKVY---K---DYNS---ALISLTKE-E---QGK---F---DYIKGDSEGFVNIPLSIKNVC------FS-CFLRE--DTE-MIKISLRSVGKFPCNRLAAEF-----FNGGGHLNASGGEFYG--TMEEAVKVFEQALEKY-----
2 PsiBlast_PDB 90.6825% -64 - C2 -4PY9 ? A:[4-337] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KVIAQAHIDHFTKWFERADKIVIVSHVSPDGDAIGSS-LGL--------YHFLD--SQDK-----------IVNVI-VPN----AFPDFLKWMPGSKDI--LLYDRY-QEFAD--KLIMEADVICCLDFNALKR-----IDEMSDIVAA------------------------SPGRKIMIDHHLYPEDFC-------RITI-SHPE-------ISSTSELVFRLI-------------CR--MGY------FS--DISKEGAECI-YTGMMTDTGGFTY-NSNNRE----------I-------------YFIISE-LL---------------------SK-----------GI--D-----------------K--DDIYRKVY----------NTYSESRLRLMGYVL----SNMKVY---K---DYNS---ALISLTKE-E---QGK---F---DYIKGDSEGFVNIPLSIKNVC------FS-CFLRE--DTE-MIKISLRSVGKFPCNRLAAEF-----FNGGGHLNASGGEFYG--TMEEAVKVFEQALEKY-----
21 HHSearch 81.9319% -68 - C2 -3DEV ? A:[5-312] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FNEIMQRVKE----AETIIIHRHVRPDPDAYGSQ-LGL--------KLYLE--RKFP-----------EKNIY-ATG----E------AEPSLS-F--I--GDL-D-------E-------------IDDS-----VYSDALVIVCDTANAPRIDDQ-----R-YL----NGQSLIKIDHHPATDQY-------GDVNF-VNTE-------ASSTSEIIFDFI-------------SH--FND------LS--IIDEHVARVL-YLGIVGDTGRFLFSNTSPH-----------T-------------MEVASQ-LL---------------------AY-----------PF--N-HNA----ELNKM-S--E--KDP---------------KLMPF-QGYV----L----QNFELS---D---SH-----EYCQIKITND---VLKQFDI---QPNEASQFVNTVADISGLKIW------MF-GV-DE--G--DQIRCRIRSKG-ITI-NDVANQ-----FGGGGHPNASGVSVYSWDEFEELAQALRQKL--------
3 PsiBlast_PDB 74.6929% -56 - C2 -4LS9 ? A:[24-218] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ARVDARGAADLLTA----ASSVSVICHVYPDADTIGAG-LAL--------AQVLA--ASGK-----------H-----VEV----S-----FATP--AQL--P--ESL-QSLPGG-HLLVAPEA-------MRRD--------ADLVVTVDI--PS--INRLGALSGLAG----PGREVLVIDHHASNQLFGT----A---NY-IDPS-------ADSTTMLVAELL-------------DAWGKPI------DE--KV----AHCL-YAGLTTDTGSFRW-AT-AR-----------A-------------HRLAAR-LV---------------------EL-----------GV--D-NAS----IS-RT-L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50 Fugue 71.1217% -37 - C2 -4K70 ? A:[2-483] -PGSMEALVRALEEADHAVATVVQSRILEFFM-------AAGRETPAGVRGLWARALRLACRAYVETGT-----CEAAVLAENLAGLALWR------------LRHDWDEGT-------APLLELLGVVNGDDTTAALTEA------------------------------GLRTSAEFGPDAMFR----LVSEWCAAFDEALAGARS----------ADDVLAAPRVVPPEQTARALVQPRFA-TLYDMDF-VQDGLRYVA--QHTNWALPLALAVRQMQ------NE--GLKPLTRALFALTIADEF-------------FHDRQNPTLREQFAEAARAVDEAALVPVGE----VNAT------------PRTA-VEV--------RVSAA--LAHG-----------DAYVRELRP----G-----T----------------------VARRLRTDQG-------VLAL-----LDPGAQAVHVAAAAD-------------LD----H-TQVDATGVWEAVQA-------------------------SASPLQVVEALV-------------TA--GFT------RR--HCDLLERAVL------------------DR-----------A-------------PRLTDA-QR---------------------AV-----------GC----TAV----VG-GV-V--H--RLL---------------DDYGP-GLDY----V----RAYTDV---A---D------TLEPLYGD-V---TAA---L---G-----------LPEKGVEHV------VR-HCMAP--R--PPTEHVGAARAALLR-EVAAAE-----RRAGLAHSAAREALNT-WLAFRAQSRWGL----------
22 HHSearch 70.6017% -53 - C2 -2HAW PPAC_BACSU A:[2-280] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EKILIFGHQNPDTDTICSA-IAY--------ADLKN--KLGF-----------NAEPV-RLG----Q------VNGETQYA--L--DYF-KQES---PRLVE------------TA-----ANEVNGVILVDHNERQQSIK-------DIE----EVQVLEVIDHHRIANFETA----EPLY-Y-RAEP-------VGCTATILNKMY-------------KE--NN--------V--KIEKEIAGLM-LSAIISDSLLFKSPTCTDQ-----------D-------------VAAAKE-LA---------------------EIA----------GV--D-AEE----YGLNM-L--KAGADL---------------SKKT--VEEL----IS---LDAKEF---TLGSK------KVEIAQVNTV---DIEDVKK---RQAELEAVISKVVAEKNLDLF------LL-VI-TDILE--NDSLALAIGNE---A-AKVEKA-----FNV------------------------------------
23 HHSearch 67.4417% -42 - C2 -2EB0 PPAC_METJA A:[2-306] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RYVVGHKNPDTDSIASA-IVL--------AYFLD--CYPA-----------R------LG----D------INPETEFV--L--RKF-GVME---PELIE-------------------SAKGKEIILVDHSEKSQSFDD-------LE----EGKLIAIIDHHKVGLTT-T----EPILYY-AKP--------VGSTATVIAELY-------------FK--DAIDLIGGKKK--ELKPDLAGLL-LSAIISDTVLFKSPTTTDL-----------D-------------KEMAKK-LA---------------------EIA----------GI--SNIEE----FGMEI-L--KAKSVV---------------GKLKP-EEII----N----MDFKNF---DFNGK------KVGIGQVEVI---DVSEVES---KKEDIYKLLEEKLKNEGYDLI------VF-LI-TDIMK--EGSEALVVGNK-----EMFEKA-----F---V--EGNSVFLEG--VMS-RKKQVVPPLERAYN---
4 PsiBlast_PDB 66.8124% -65 - C2 -3DEV ? A:[4-178] -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IFNEIMQRVKE----AETIIIHRHVRPDPDAYGSQ-LGL--------KLYLERKFPEK-----------NIYAT--------G-----EAEPSLSFIGDL--DEI-DD-----------------------S-----VYSDALVIVCDTANAPRIDDQ-----RYLN----GQS-LIKIDHHPATDQY-G----DVNFVN-TE---------ASSTSEIIFDFI-------------SH--FND------LS--IIDEHVARVL-YLGIVGDTGRFLFSNTSPH-----------T-------------MEVASQ-L------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49 Fugue 66.1318% -56 - C2 -1I74 PPAC_STRMU A:[1-309] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKILVFGHQNPDSDAIGSSMA-Y--------AYLKR--QLGV-----------DAQAV-A-L----G-----NPNEETAFV--L--DYFGIQAPPVVKSAQAEGA--------------------KQVILTDHNEFQQSIAD-------IR----EVEVVEVVDHHRVANFETA----NPL--YMRLEP-------VGSASSIVYRLY-------------KE--N---------G--VAIPKEIAGVMLSGLISDTLLLKSPTTHAS-----------D-------------PAVAED-LA---------------------KIAGV--------DL--Q-EYG----LAMLK-A--G--TNL---------------ASKTA-AQLV----D----IDAKTF---EL--N------GSQVRVAQ-V---NTV---D---INEVLERQNEIEEAIKASQAANGYSDFVLMITDIL--N--SNSEILALGNNTDKV-EAAF----------NFTLKNNHAFLAG-A--VSRKKQVVPQLTESFNG--
48 Fugue 64.4618% -48 - C2 -1K20 PPAC_STRGC A:[1-310] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKILVFGHQNPDSDAIGSS-YAF--------AYLAR--EAYG-----------LDTEA-VAL----G-----EPNEETAFV--L--DYF-----GVAAPRVITSA-------KAEG-----A---EQVILTDHNEFQQSVAD-------IA----EVEVYGVVDHHRVANFETA----NPLYMR-LEP--------VGSASSIVYRMF-------------KE--HS--------V--AVSKEIAGLM-LSGLISDTLLLKSPTTHPT-----------D-------------KAIAPE-LA---------------------ELA----------GV--N-LEE----YG-LA-M--L--KAG---------------TNLAS-KSAE----ELIDIDAKTFE---L---N------GNNVRVAQ-V---NTV---D---IAEVLERQAEIEAAIEKAIADNGYS--DF-VLMIT--D--IINSNSEILAIGSNM-DKVEAA-----FNF--VLENNHAFLAG-A--VSRKKQVVPQLTESFNA--
26 HHSearch 63.8714% -54 - C2 -2QB7 PPX1_YEAST A:[26-324] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N----DVLTICVGNESADMDSIASA-ITY--------SYCQY--IYNEGTYSEEKKKGSFIVPI-IDIPREDL-----SLRRDVMYV--L--EKL-KIKE---EELFFIED-------LKSLKQNVSQGTELNSYLVDNNDTPKNLK------N-Y-----IDNVVGIIDHHFDLQKHLD-----AEPRI-VKV--------SGSCSSLVFNYW-------------YE--KLQG-----DR--EVVMNIAPLL-MGAILIDTSNMRR-KVEES-----------D-------------KLAIER-CQ---------------------AVLSGAVNEVSAQGLE-D-SSE----FYKEI-KSRK--NDI---------------KGFSV-SDIL----K----KDYKQF---NFQ-GKGHKGLEIGLSSIV-KRMSWLF---NEHGGEADFVNQCRRFQAERGLDVL------VL-LT--------------------------------------------------------------------------
20 PsiBlast_PDB 63.3721% -22 - C2 -1K23 PPAC_BACSU A:[2-219] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EKILIFGHQNPDTDTICSA-IAY--------ADLKN--KLGF-----------NA-----EPVRL-G-----QVNGETQYA--L--DYF-KQE--------SPRL-------VETA-----ANEVNGVILVDHNERQQSIKD-------IE----EVQVLEVIDHHRIANFETA----EPLYYR-AEP--------VGCTATILNK---------------MY--KEN------NV--KIEKEIAGLM-LSAIISDSLLFKS-PTCTD-----------QDVAAAKELAEIAGVDAEEYGLN---------------------ML-----------KA--G-ADLSKKTVE-EL-I--S--LDA---------------KEFTL-GSKK----V----EIAQV------------------------------------------------------------------------------------------------------------------------------------------------
24 HHSearch 62.6621% -50 - C2 -1WPN PPAC_BACSU A:[2-185] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EKILIFGHQNPDTDTICSA-IAY--------ADLKN--KLGF-----------NAEPV-RLG----Q------VNGETQYA--L--DYF-KQES---PRLVE------------TA-----ANEVNGVILVDHNERQQSIK-------DIE----EVQVLEVIDHHRIANFETA----EP-LYY-RAEP-------VGCTATILNKMY-------------KE--NN--------V--KIEKEIAGLM-LSAIISDSLLFKSPTCTDQ-----------D-------------VAAAKE-LA---------------------EIA----------GV--D-AEE----YGLNM-L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25 HHSearch 59.7615% -60 - C2 -2ZXR RECJ_THET8 A:[62-422] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AALLEEALRQ----GKRIRVHGDY--DADGLTGT-AIL--------VRGLA--ALGA-----------DVHPF-IP---------------------------------------------------------------SDLFLTVDC-----------------------GVEVIVTDHHT---------------LV-VHPALTPDLKEKPTGAGVAFLLL-------------WA--LHE------RLGLPPPLEYADLA-AVGTIADVAPLWG-WNRALVKEGLARIPASS-------------WVGLRL-LAEAVGYTGKAVEVAFRIAPRINAA-----------SRLGE-AEK----AL-RLLL--T--DDAAEAQALVGELHRLNARRQTL-EEAM----L----RKLLPQADPE---A------KAIV-LLD------PE---G---HPGVMGIVASRILEATLR-PV------FL-VA-Q--------GKGTVRSLAPISA-VEALRSAEDLLLRYGGHKEAAGFAMDE-ALFPAFKARVEAYAARFP----
52 Fugue 58.0512% -21 - C2 -1CWY - MALQ_THETH A:[1-500] -----------------------------------MELPRAFGLLLHPTSLPGPYGVG-VLGREARDFLRFLKEAGGRYWQVLPLGPTGYGDSPYQSFSAFAGNPYLIDLRPLAERGYVRLEDPGFPQGRVDYGLLYAWKWPALKEAFRGFKEKASPEEREAFAAFREREAWWLEDYALFMALKGAHGGLPWNRWPLPLRKREEKALREAKSA-----------LAEEVAFHAFTQWLFFRQWG-ALKAEAEA-------------LGIRIIGDMPIFVAE------DSAEVWAHPEWFHLD--------------EEGRPTVVAGVPPDYFSETGQRWGNPLYRWDVLERE----GFSFWIRRLEKALELF------HL--------VRIDH--FRGF-----------EAYWE-IPA----S-----CPTA--------------------------VEG-------RWVK-----APGEKLFQKIQEVFGEVPVLA-----E--D----LGVITPEVEALRDRFGLPG----MKVLQF-AFDD-------GMENPFLPHN----------------Y--PAH----------------------GRVVVYTGTHDN-DTTLG-----------W-------------YRTAT------------------------------------------------------PH-E--K--AFM---------------ARYLA-DWGI----T----FR---------------------------E---EEE---V---PWALMHLGMKS-----------------------V--A--RLAVYPVQDVLALGS-EARMNY-----PGRPSGNWAWRLLPGE-LS-PEHGARLRAMAEATERL--
28 HHSearch 57.4822% -77 - C2 -3EZU - ? A:[211-342] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GSNVGIMLIDLD----YFKLVG-----QTGDRILQLVAETITSHLR-RSDVVGRYDGDEFVVYLSPVEPA-SLRTVAENLRRSIEEES---ARMVPVTASIGVAQGILGTDVDGGIEELVRLADECLMQAKYTGKNKVVVK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10 PsiBlast_PDB 56.8720% -21 - C2 -1WPN PPAC_BACSU A:[2-166] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EKILIFGHQNPDTDTICSA-IAY--------ADLKN--KLGF-----------NA-----EPVRL-G-----QVNGETQYA--L--DYF-KQE--------SPRL-------VETA-----ANEVNGVILVDHNERQQSIKD-------IE----EVQVLEVIDHHRIANFETA----EPLYYR-AEP--------VGCTATILNKM---------------Y--KEN------NV--KIEKEIAGLM-LSAIISDSLLFKS-PTCTD-----------Q-------------DVAAA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5 PsiBlast_PDB 55.9024% -49 - C2 -2EB0 PPAC_METJA A:[3-158] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YVVGHKNPDTDSIASA-IVLAYFLDCYPARLGD--INPE-----------TEFVL-RKF----G-----VMEPEL-----------------------------------IES-----AKGKEIILVDHSEKSQSFDD--------LE----EGKLIAIIDHHK-----VGLTTTEPILYY-AKP--------VGSTATVIAELYFKDAIDLIGGKKKEL--KPD------L---------AGLL-LSAIISDTVLFKS-PT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35 HHSearch 55.6121% -60 - C2 -3ICL ? A:[28-162] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GNPVVLLFLDVD----NFKSINDSLGHLVGDRLLRATAERIRTAVR-DGDTVARIGGDKFTILLNGAKDTLNGALVAQKILDGLAQPFVFGAQQIVISVSIGIAVSPADG---ETMEQLLRNADTAMYHAKSRGKNNYQFFSP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14 PsiBlast_PDB 55.0920% -27 - C2 -2HAW PPAC_BACSU A:[2-150] ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EKILIFGHQNPDTDTICSA-IAY--------ADLKN--KLGF-----------NA-----EPVRL-G-----QVNGETQYA--L--DYF-KQE--------SPRL-------VETA-----ANEVNGVILVDHNERQQSIKD-------IE----EVQVLEVIDHHRIANFETA----EPLYYR-AEPV-------G-CTATILNKM---------------Y--KEN------NV--KIEKEIAGLM-LSAIISDS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------