@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0087: (2016-03-12 )
MKPTWKIGIIVAAVPLIIIAVVLWGSFKEARYNLVSLPDDGVVLNNEQETLQFQKGNTLYRSWNSDQLIAKNDKEDTRNEIMESTILYLNKEALMFTKSVPVIDTNGVSSKLKGRQVYQQTNSSYKYKNSEIVENSIVKLANRQYYLNADATLYLGGKEIKKVTKPLLLIDKTGSVTIYENKKKSRFLGHMTLKVNDKTVLDASNETYTVGERKIDLASFGGTDNEKIVVKEDEKKEDKKKTAESAKKTASNTSQSENESNQTTKGTGNQLNATKKYGNNLNVGNGTSDSEPNDGKDTKNNGSGSNANGGTNQSGLNEIDDYEAVLRKIEDLNKKLERNIPVLRIGYIAPGVTSVKVSYNYADPNNTLIGVTKISAVDEKTGKTVNTQYVSAVDTEATLKGLSPNGKYHLEFTYQYDLGTNKGIQEVKMQSDSFTTQTVAAIYQMQSVTSTTMKVNIALDAQIDDVKRARIKVTKSDGDFFYMNVSANFLNGNGEILNATGLKPSTAYQFQTVIEMKNGETIELNSSEKYYTMQATVLKNLKASQSVNKVLQVQYDWSSADYTLNQAIIELEDEEDNTEVDYQIVNQEKGNIHLVPDTKSELINLKAKLVLKTTNNNTKESKTFEYPVKQEIEYDKQAKLTMDLTPFQTEENSEAQTEKQDVVAEKETNGNDLTAKMEDVLAPQNATYDMSFSMQRKALETYQLAFERKIAGIDDDNWTMWKSQQVTTDEAGQVKVTETISKLAKDSFDYRVAVYDAQGALQLYVYQK
Atome Classification :
(20 SA)
.........10.......--.20........30........40........50........60........70........80.-.......90........100.......110.......120-----.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340..---.....350.......360.......370.......380.....-----..390.....---..400.......410.......420.......430...-....440.---------------------.---..---.-------.---.-----.450.....-------.------.-460.........470--------------........--.480.....-----.-..-------------.490...---.--...500.......510......----------..520.....---..530.......540.......550...---....560.......570.......580--------.........590.......600.......610.......620------......----..630.......640.......650.......660-.......670.......680.......690.......---700.......710.......720.......730.......740.......750.......760......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MKP
T
W
K
I
G
I
I
V
A
A
V
P
L
I
I
--
I
A
V
V
L
WGS
F
K
E
AR
Y
N
L
V
SLPDD
G
V
V
LNNEQ
E
T
L
Q
FQKG
N
T
L
Y
RSWNSD
Q
L
I
AKNDK
E
D
T
R
N
E
I
M
-
E
S
T
I
L
YLNKE
A
L
M
FTKSVPVIDTNGVSSKLKG
R
Q
V
Y
Q
QTN-----SSYKYKN
S
E
I
V
E
N
S
I
V
K
LANR
Q
Y
Y
LNAD
A
T
L
Y
LG
G
K
E
I
K
K
VTK
P
L
L
L
I
DKTG
S
V
T
I
Y
ENKKKS
R
F
L
G
H
M
T
L
K
VND
K
T
V
LDASNE
T
Y
T
VG
E
R
K
I
D
L
A
SFGGTDN
E
K
I
V
VKEDE
K
K
E
D
K
K
K
T
A
E
S
A
K
KTASNTSQSENESNQTTKGTGNQLN
A
T
K
KYGNNLNVGNGTSDSEPNDGKDTKNNGSGSNANGGTNQSGLNEID
D
Y
E
A
V
L
R
K
I
E
D
L
N
K
K
L
E
RNI
P
V
L
R
---
I
G
Y
IAPG
V
T
S
V
K
V
S
Y
N
YADPNN
T
L
I
G
V
T
K
I
S
AVDEKTG
K
T
V
N
T
-----
Q
Y
V
S
AVDT
E
A
---TLKGLSPN
G
K
Y
H
L
E
F
T
Y
Q
Y
DLGTNKG
I
Q
E
V
KMQSDSF
T
-
T
Q
T
V
A
A
-
I
---------------------
Y
---
Q
M
---
Q
-------S---V-----TS
T
T
M
K
V
N
I
-------
A
------
L
-
D
--AQIDDV
K
R
A
R
----------------
I
K
V
TKSDG--
D
F
--
F
Y
M
N
V
-----
S
-
A
N
-------------
F
LNGNG
E
---
I
--
L
N
ATGLKPST
A
Y
Q
F
-
Q
T
V
I
E
MK----------NG
E
T
I
E
LNSS---E
K
Y
Y
T
M
Q
A
T
V
L
K
N
L
K
A
S
Q
S
V
N
K
V
L
Q
V
Q
Y
---DWSSAD
Y
T
L
N
Q
A
I
I
E
LEDEEDNT
E
V
----------
D
Y
Q
I
V
NQEKG
N
I
H
L
VPDT
K
S
E
L
I
N
L
K
A
K
L
V
L
K
TTNNNTKES-------KTFEYP----
V
K
Q
E
IEYDKQ
A
K
L
T
M
DLTPFQTEENSEAQ
T
E
K
Q
D
V
-
V
AEKETNGND
L
T
A
K
M
E
D
VLAPQNATYDM
S
F
S
M
Q
R
K
A
L
---
E
T
Y
Q
L
A
F
E
R
KIAGIDDDN
W
T
M
W
KSQQVTTDEAG
Q
V
K
V
T
E
T
I
S
K
L
A
KDSF
D
Y
R
V
A
V
Y
DAQG
A
L
Q
L
Y
V
YQK
33
Fugue
77.42
17%
25
- C2 -
3WKX
2
HYBA1_BIFL2
A:
[1-659]
M
N
V
T
I
T
S
P
F
W
K
R
R
R
D
Q
I
V
E
S
V
I
P
Y
Q
W
G
V
M
N
D
E
I
D
T
--
T
V
P
D
D
---------
P
A
G
N
Q
L
A
D
S
K
S
H
A
V
A
N
L
K
V
A
A
G
E
L
D
D
E
F
H
G
M
V
F
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D
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D
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Y
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W
L
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A
A
Y
A
L
A
Y
H
P
D
P
E
L
K
A
L
C
D
R
T
V
D
L
I
A
R
A
Q
Q
S
DGYLD
T
P
Y
Q
I
K
S
G
V
W
A
D
R
P
R
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L
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Q
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H
E
M
Y
V
M
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H
Y
I
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A
A
V
A
Y
H
Q
V
T
------------------------
G
N
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Q
A
L
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V
A
K
K
M
A
D
C
L
D
A
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F
G
P
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E
G
K
I
H
G
A
D
-
G
H
P
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I
E
L
A
L
A
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L
Y
E
E
T
G
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K
R
Y
L
T
L
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Q
Y
L
I
D
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R
G
Q
D
P
Q
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Y
A
K
Q
L
K
A
M
N
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D
N
I
F
H
G
F
Y
K
P
T
Y
F
Q
A
A
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P
V
R
D
---------
Q
Q
T
A
D
G
H
A
V
R
V
G
Y
L
C
T
G
V
A
H
V
G
R
L
L
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D
-
Q
G
L
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D
T
A
K
R
F
W
K
N
I
V
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R
MYV
T
G
A
I
G
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T
H
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F
T
Y
D
Y
D
L
P
N
D
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Y
G
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C
A
S
V
A
M
S
M
F
A
Q
Q
M
L
D
L
EPK
G
E
Y
A
D
V
L
E
K
E
L
F
NG
S
I
A
G
I
S
L
D
G
K
Q
Y
Y
---
Y
V
N
A
L
E
T
T
P
D
G
L
D
N
P
--
D
R
H
H
V
-
L
S
H
R
V
D
-
W
---------------------
F
---
G
C
---
A
-------
C
---
C
-----
P
A
N
I
A
R
L
I
A
-------
S
------
V
-
D
--
R
Y
I
Y
T
E
R
--------------------------------------------------------------
D
G
G
K
T
---
V
--
L
S
---------
H
Q
F
I
A
N
T
A
E
F
A
----------
S
G
L
T
V
E
Q
R
S
N
FPW
D
G
H
V
E
Y
T
V
S
-
L
P
A
S
A
T
D
S
S
V
R
F
G
L
R
I
-
P
---
G
W
S
R
G
S
Y
T
L
T
V
----------------------------------------
N
G
K
P
A
V
G
S
L
E
D
G
F
V
Y
L
V
V
N
A
G
D
---------------
T
----
L
E
I
A
L
E
L
D
M
S
V
K
F
V
R
A
N
S
R
V
R
S
D
A
G
Q
V
A
V
M
R
G
P
L
V
Y
C
A
E
Q
V
D
N
P
G
D
L
W
N
---
Y
R
L
A
D
G
V
T
G
A
D
A
A
V
A
F
Q
A
D
L
L
G
G
V
D
T
V
D
L
P
A
V
R
E
H
A
D
-
E
D
D
A
P
L
Y
V
D
A
D
E
P
R
A
G
E
P
A
T
L
R
L
V
P
-----------
Y
Y
S
W
A
N
R
E
I
G
E
M
R
V
F
Q
R
R
A
35
Fugue
56.97
18%
33
- C2 -
4HNE
1
P4K2A_HUMAN
A:
[2-384]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
L
G
S
P
E
F
A
A
Q
A
Q
A
L
A
-
A
Q
A
A
A
A
-
A
---------------------
H
---
A
A
---
Q
-------
A
---
H
R
----
E
R
N
E
F
P
E
D
P
-------
E
------
F
-
E
--
A
V
V
R
Q
A
E
L
A
I
E
R
CI
F
P
E
R
IYQGSSG
S
Y
F
V
K
D
P
Q
G
--
R
I
--
I
A
V
F
K
-----
P
-
K
N
EEPYGHLNPKW
T
K
W
L
Q
K
F
G
R
DCL
V
--
L
N
Q
G
Y
L
S
E
A
G
A
S
L
V
-
D
Q
K
L
E
L
N
IVPRT
K
V
V
Y
L
A
S
E
T
F
N
Y
S
A
I
---
D
R
V
K
S
R
G
K
R
L
A
L
R
F
N
R
I
G
L
P
P
K
V
G
S
F
Q
L
F
V
E
G
Y
K
D
A
D
Y
W
L
R
R
F
E
A
E
P
L
P
E
N
T
N
R
Q
L
L
L
Q
F
E
R
L
V
V
L
D
Y
I
I
R
N
T
D
R
G
N
-------
D
N
W
L
I
K
Y
D
C
P
P
V
I
K
V
A
A
I
D
N
G
L
A
-------
F
P
L
K
H
P
----
D
S
W
R
A
Y
P
F
Y
W
A
W
L
P
Q
A
K
V
P
F
S
Q
E
I
K
D
L
I
L
P
K
I
S
D
------
P
N
F
V
K
D
L
E
E
D
L
Y
E
L
F
K
K
D
P
G
F
D
R
G
Q
F
H
K
Q
I
A
V
M
---
R
G
Q
I
L
N
L
T
Q
A
L
K
D
-
N
K
S
P
L
H
L
V
Q
M
P
P
V
I
V
E
T
--------------------------------------
17
HHSearch
54.45
18%
-3
* C3 *
3CSG
-
MALE_ECOLI
A:
[356-447]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
V
D
E
A
L
K
D
A
Q
T
R
I
T
K
G
S
S
V
P
T
N
L
E
-----
V
V
A
A
T
P
T
S
L
L
I
S
W
D
A
S
Y
-
S
S
S
V
S
Y
-
Y
R
I
T
Y
G
E
T
G
G
N
S
P
V
Q
E
-----
F
T
V
P
G
S
K
S
T
A
---
T
I
S
G
L
S
P
G
V
D
Y
T
I
T
V
Y
A
Y
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
51.29
19%
-18
- C3 -
1TDQ
-
A:
[159-275]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
T
K
T
---
T
L
T
D
L
V
P
G
T
E
Y
G
V
G
I
S
A
V
M
N
S
K
Q
--
S
------
I
P
A
T
M
N
-
A
R
T
E
L
D
-
S
---------------------
P
---
R
D
LMV
T
-------
A
---
S
-----
S
E
T
S
I
S
L
I
W
T
------
K
------
A
-
S
--
G
P
I
D
H
Y
---
R
----------------
I
T
F
T
P
S
S
G
--
I
S
--
S
E
V
T
V
------------------------
P
R
D
R
T
---
S
--
Y
T
L
T
D
L
E
P
G
A
E
Y
I
I
-
S
I
T
A
E
R
G
----------
R
Q
Q
S
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
49.86
17%
-14
- C3 -
1TDQ
-
A:
[63-184]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Q
P
P
L
S
Q
Y
---
S
V
Q
A
L
R
P
G
S
R
Y
E
V
S
I
S
A
V
R
G
T
N
E
S
------
D
A
S
S
T
Q
F
T
---
T
E
I
D
-
A
---------------------
P
---
K
N
L
R
V
G
-------
S
---
R
-----
T
A
T
S
L
D
L
E
W
-------
D
------
N
S
E
--
A
E
A
Q
E
Y
---
K
----------------
V
V
Y
S
T
L
A
G
--
E
Q
Y
-
H
E
V
L
V
-----
P
-
K
---------------
G
I
G
P
T
T
---
K
--
T
T
L
T
D
L
V
P
G
T
E
Y
G
V
-
G
I
S
A
V
M
N
----------
S
K
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
HHSearch
48.37
20%
-26
- C3 -
3T1W
-
FINC_HUMAN
A:
[1407-1522]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
S
P
S
D
N
A
V
---
V
L
T
N
L
L
P
G
T
E
Y
V
V
S
V
S
S
V
Y
E
Q
H
E
S
---
T
P
L
-----
R
G
R
-
Q
K
T
G
L
D
-
S
---------------------
P
TGI
D
F
---
S
-------
D
---
I
-----
T
A
N
S
F
T
V
H
W
I
------
A
------
P
-
R
--
A
T
I
T
G
Y
---
R
----------------
I
R
H
H
P
E
H
F
SG
R
P
--
R
E
D
R
V
-----
P
-------------------
H
S
R
N
---
S
--
I
T
L
T
N
L
T
P
G
T
E
Y
V
V
-
S
I
V
A
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
HHSearch
46.56
18%
-18
- C3 -
1FNF
-
FINC_HUMAN
A:
[1376-1495]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
H
S
R
N
S
I
---
T
L
T
N
L
T
P
G
T
E
Y
V
V
S
I
V
A
L
N
G
R
E
E
--
S
P
------
L
L
I
G
Q
-
Q
S
T
V
S
D
-
V
---------------------
P
---
R
D
---
L
-------
E
VVA
A
-----
T
P
T
S
L
L
I
S
W
-------
D
------
A
P
A
--
V
T
V
R
Y
Y
---
R
----------------
I
T
Y
G
E
T
G
G
--
N
S
P
V
Q
E
F
T
V
------------------------
P
G
S
K
S
---
T
--
A
T
I
S
G
L
K
P
G
V
D
Y
T
I
-
T
V
Y
A
V
T
G
----------
R
G
D
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
46.20
22%
-13
- C3 -
2JLL
1
NCAM2_HUMAN
A:
[250-374]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
Q
T
M
V
---
V
L
N
N
L
E
P
N
T
T
Y
E
I
R
V
A
A
V
N
G
K
G
Q
G
----
D
---
Y
S
K
I
E
I
-
F
Q
T
L
P
V
R
E
---------------------
P
---
S
P
---
P
-------
S
---
I
H
G
Q
P
S
S
G
K
S
F
K
L
S
I
TK-----
Q
------
D
-
D
GG
A
P
I
L
E
---
Y
I
----------------
V
K
Y
R
S
---------
Q
W
L
E
K
----------------------
K
V
Q
G
N
K
D
---
H
--
I
I
L
E
H
L
Q
W
T
M
G
Y
E
V
-
Q
I
T
A
A
N
R
----------
L
G
Y
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
45.56
17%
-33
- C3 -
3R8Q
-
A:
[48-166]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
N
L
A
P
D
S
S
S
V
---
V
V
S
G
L
M
V
A
T
K
Y
E
V
S
V
Y
A
L
K
D
T
L
T
S
R
P
A
------
Q
G
V
V
T
T
L
E
N
V
S
P
-
P
---------------------
R
RA-
R
V
---
T
-------
D
---
A
-----
T
E
T
T
I
T
I
S
W
-------
R
T
-----
K
-
T
--
E
T
I
T
G
F
---
Q
----------------
V
D
A
V
P
A
N
G
--
Q
T
P
-
I
Q
R
T
------------------------
I
K
P
D
V
R
---
S
--
Y
T
I
T
G
L
Q
P
G
T
D
Y
K
I
-
Y
L
Y
T
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
41.82
14%
13
- C3 -
3L5I
14
A:
[154-277]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
V
H
R
T
Y
---
L
R
G
N
L
A
E
S
K
C
Y
L
I
T
V
T
P
V
Y
A
D
G
P
G
----
S
P
E
-
S
I
K
A
Y
L
-
K
Q
A
P
P
S
-
K
---------------------
G
---
P
T
V
R
T
K
-------
K
---
V
-----
G
K
N
E
A
V
L
E
W
-------
D
Q
LPVDV
Q
-
N
--
G
F
I
R
N
Y
---
T
----------------
I
F
Y
R
T
I
I
G
--
N
E
--
T
A
V
N
------------------------
V
D
S
S
H
T
---
E
--
Y
T
L
S
S
L
T
S
D
T
L
Y
M
V
-
R
M
A
A
Y
T
D
----------
E
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
41.61
28%
68
- C2 -
2VL8
1
?
A:
[65-202]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
----------
S
G
R
N
K
A
L
K
K
F
---
K
E
Y
L
T
M
E
V
L
E
L
K
N
-
N
S
L
T
P
V
E
K
N
L
H
--
F
---
I
W
I
G
G
Q
--
I
N
D
T
A
I
N
Y
I
N
Q
W
K
D
V
N
S
----------
D
Y
--------
T
V
K
V
F
Y
D
S
N
A
F
L
I
N
T
L
K
K
T
I
V
E
S
A
T
N
N
T
L
E
S
F
R
ENLND
P
E
F
D
Y
N
K
F
Y
R
K
R
M
E
I
I
Y
D
K
Q
-
K
H
F
I
D
Y
Y
K
S
Q
I
E
E
N
P
E
----------------------------------------------------------------------------------------------------------------------
15
HHSearch
40.77
15%
-3
- C3 -
1QR4
-
TENA_CHICK
A:
[47-164]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
V
D
S
T
S
F
---
I
L
R
G
L
D
A
G
T
E
Y
T
I
S
L
V
A
E
K
G
R
H
K
S
------
K
P
T
T
I
K
G
S
---
T
V
V
G
-
S
---------------------
P
---
K
G
I
S
F
S
-------
D
---
I
-----
T
E
N
S
A
T
V
S
W
-------
T
P
-----
P
-
R
--
S
R
V
D
S
---
Y
R
----------------
V
S
Y
V
P
I
T
G
--
G
T
--
P
N
V
----------
V
-------------
T
V
D
G
S
K
T
---
R
--
T
K
L
V
K
L
V
P
G
V
D
Y
N
V
-
N
I
I
S
V
K
G
----------
F
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
40.47
28%
69
- C2 -
2VKD
1
?
A:
[65-199]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
----------
S
G
R
N
K
A
L
K
K
F
---
K
E
Y
L
T
M
E
V
L
E
L
K
N
-
N
S
L
T
P
V
E
K
N
L
H
--
F
---
I
W
I
G
G
Q
--
I
N
D
T
A
I
N
Y
I
N
Q
W
K
D
V
N
S
----------
D
Y
--------
T
V
K
V
F
Y
D
S
N
A
F
L
I
N
T
L
K
K
T
I
V
E
S
A
T
N
N
T
L
E
S
F
R
ENLND
P
E
F
D
Y
N
K
F
Y
R
K
R
M
E
I
I
Y
D
K
Q
-
K
H
F
I
D
Y
Y
K
S
Q
I
E
E
N
P
E
----------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
40.19
28%
73
- C2 -
2VKH
1
?
A:
[65-202]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
----------
S
G
R
N
K
A
L
K
K
F
---
K
E
Y
L
T
M
E
V
L
E
L
K
N
-
N
S
L
T
P
V
E
K
N
L
H
--
F
---
I
W
I
G
G
Q
--
I
N
D
T
A
I
N
Y
I
N
Q
W
K
D
V
N
S
----------
D
Y
--------
T
V
K
V
F
Y
D
S
N
A
F
L
I
N
T
L
K
K
T
I
V
E
S
A
T
N
N
T
L
E
S
F
RENLND
P
E
F
D
Y
N
K
F
Y
R
K
R
M
E
I
I
Y
D
K
Q
-
K
H
F
I
D
Y
Y
K
S
Q
I
E
E
N
P
E
----------------------------------------------------------------------------------------------------------------------
11
HHSearch
39.60
18%
71
- C- -
1ZLG
-
KALM_HUMAN
A:
[482-642]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
H
E
N
Y
I
---
I
L
Q
D
L
S
F
S
C
K
Y
K
V
T
V
Q
P
I
R
P
K
S
H
S
------
K
A
E
A
V
F
F
T
-
T
P
P
C
S
A
-
L
KGKSHKPIGCLGEAGHVLSKV
L
---
A
K
---
P
E
N
L
S
AS
F
I
---
V
-----
Q
D
V
N
I
T
G
H
F
S
W
K
M
A
KA
N
------
L
-
Y
--
Q
P
M
T
G
F
---
Q
----------------
V
T
W
A
E
V
T
T
--
E
S
--
R
Q
N
S
L
P
N
S
I
I
S
Q
S
Q
-------------
I
L
P
S
D
H
Y
---
V
--
L
T
V
P
N
L
R
P
S
T
L
Y
R
L
-
E
V
Q
V
L
T
P
----------
G
G
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
38.79
14%
-5
- C3 -
3L5H
1
IL6RB_HUMAN
A:
[455-576]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
R
T
Y
---
L
R
G
N
L
A
E
S
K
C
Y
L
I
T
V
T
P
V
Y
A
D
G
P
G
----
S
P
E
S
-
I
K
A
Y
L
-
K
Q
A
P
P
S
K
G
---------------------
P
---
T
V
R
T
-
K
-------
K
---
V
-----
G
K
N
E
A
V
L
E
W
-------
D
Q
LPVDV
Q
-
N
--
G
F
I
R
N
Y
---
T
----------------
I
F
Y
R
T
I
I
G
--
N
E
--
T
A
V
N
V
--------------------------
D
S
S
---
H
TE
Y
T
L
S
S
L
T
S
D
T
L
Y
M
V
-
R
M
A
A
Y
T
D
----------
E
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
Fugue
35.06
19%
280
- C2 -
2KK7
-
VATE_METJA
A:
[1-52]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
V
K
L
M
G
V
D
K
I
K
S
K
I
L
D
D
A
K
A
E
A
N
K
I
I
S
E
A
E
A
E
K
A
K
I
L
E
K
A
K
E
E
A
E
K
R
K
A
E
I
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
34.59
20%
427
- C2 -
2QDQ
-
A:
[2496-2529]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
G
I
A
Q
I
I
A
A
Q
E
E
M
L
R
K
E
R
E
L
E
E
A
R
K
K
L
A
Q
I
R
Q
Q
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
34.16
25%
111
- C2 -
3W5M
-
?
A:
[749-826]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
V
S
D
E
T
P
K
D
V
I
-
A
T
A
Y
F
A
H
S
A
D
L
A
A
R
M
A
T
E
L
G
K
D
A
A
P
Y
T
D
L
F
T
R
I
R
K
A
F
---
Q
T
A
Y
V
A
S
D
G
K
V
K
G
D
T
Q
S
A
Y
V
L
T
L
S
M
N
L
V
P
D
---------------------------------------
41
Fugue
34.12
19%
164
- C2 -
2IC6
-
?
A:
[2-72]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
T
L
K
E
V
Q
D
N
I
-------
T
L
H
E
Q
R
----
L
V
T
T
R
Q
K
L
K
D
A
E
R
A
V
E
L
D
P
--
D
D
V
N
K
S
T
L
Q
S
R
R
A
A
-
V
S
A
L
E
T
K
L
G
E
L
K
R
E
L
A
D
L
I
A
A
Q
---------------------------------------------------------------------------------------