@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0109: (2016-03-12 )
MLKINTTTFNPQILYIANCYTNEVRVGENHHHDFLEISIICEGNVIYDIEGERVKLGKGDMLIFNPGVSHYDITEPGMTNAQLHIGFRNFALEGYTRNTFPFKKAFLRKKEEESAILSISKQIIEEKDAGKPGYDLILKAFVMQLIIHVLREATPEQLENNGVKLSTDEQQKQILVNEIIHYMEKHHTEDVSLSTLSQTMYISPAYISKVFKEETGESPINYLIKIRLTRAEELLKNKDVSVKQAANMVGYNDAYYFSKLFKKYYGFPPSENWRKSS
Atome Classification :
(20 SA)
--------------------------------------------------------------------------.........10........20........30..--......40.......------------.50--........60....-....70----.---------------.....--..80........90-------...-------.....--100.......110--....----...-.120....---...130.....--..140.......150-....------------------------...160.......170...----------....---180..------------....-..-190.......200.......210.......220.......230......--..240.......250----------------........260....---...270....-.----------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------------------------------------------------------------------
M
L
K
I
NTTTFN
P
Q
I
L
Y
I
ANCYTN
E
V
RVGENHHH
D
--
F
L
E
I
S
I
I
CEG
N
V
I
Y
D------------IEG--
E
R
V
KLGKG
D
M
L
I
FN-PGVSHY----D---------------ITEPG--MTN
A
Q
L
H
I
G
F
R
N
F
A
-------LEG-------YTRNT--F
P
F
K
K
A
F
L
R
K
K
E
---E
E
S
A
----
I
L
S
-
I
S
K
Q
I
I
E
E---KDAGK
P
G
Y
D
L
I
--
L
K
A
F
V
M
Q
L
I
I
H
V
L
R
E-A
T
P
E
------------------------
Q
L
ENNG
V
K
LS
T
D
E
Q
Q
K
Q
I
L
----------
V
N
E
I
---
I
H
-
Y
M
------------
E
K
HH-TE-DV
S
L
S
T
LS
Q
T
M
Y
I
S
P
A
Y
I
S
K
V
F
K
E
ETGE
S
P
I
N
Y
L
I
K
I
R
L
T
R
A
-
E
E
L
L
KN--KDV
S
V
K
Q
A
A
N
MVGY-----------------N
D
A
Y
Y
F
S
K
L
F
K
K
YYG---FPPSENWRKS-S----------
1
PsiBlast_PDB
78.17
34%
-77
- C2 -
3OOU
1
?
A:
[4-105]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
P
I
----------
I
Q
N
V
---
L
S
-
Y
I
------------
T
E
H
F
-
S
E
-
G
M
S
L
K
T
L
G
N
D
F
H
I
N
A
V
Y
L
G
Q
L
F
Q
K
E
M
G
E
H
F
T
D
Y
L
N
R
Y
R
V
N
Y
A
K
E
E
L
L
Q
T
--
K
D
-
N
L
T
I
I
A
G
K
S
G
Y
-----------------
T
D
M
A
Y
F
Y
R
Q
F
K
K
H
T
G
---
E
T
P
N
R
-
Y
R
K
-------------
21
HHSearch
77.71
25%
-73
- C2 -
3MN2
2
?
A:
[3-106]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
----------
V
R
Q
V
---
E
E
-
Y
I
------------
E
A
N
W
-
M
R
-
P
I
T
I
E
K
L
T
A
L
T
G
I
S
S
R
G
I
F
K
A
F
Q
R
S
R
G
Y
S
P
M
A
F
A
K
R
V
R
L
Q
H
A
-
H
N
L
L
S
D
GA
T
P
T
T
V
T
A
A
A
L
S
C
G
F
-----------------
S
N
L
G
H
F
A
R
D
Y
R
D
M
F
G
---
E
K
P
S
E
T
L
Q
R
A
------------
19
HHSearch
77.14
14%
-63
- C2 -
3GBG
1
TCPN_VIBC3
A:
[22-270]
----------------------------------------------------------------------------------------------------
F
N
N
L
Y
I
N
--
D
Y
K
M
F
W
I
D
S
G
I
A
K
L
I
------------
D
K
N
CL
V
S
Y
E
I
N
S
S
S
I
I
L
L
K
-
K
N
S
I
Q
R
----
F
---------------
S
L
T
S
L
SD
E
N
I
N
V
S
V
I
T
I
S
D
S
F
-------
I
R
S
-------
L
K
S
Y
I
LG---
N
K
D
L
L
L
W
N
C
----
E
H
N
----
D
I
A
-
V
L
S
E
V
V
N
G
---
F
R
E
-
I
N
Y
S
D
E
F
--
L
K
V
F
F
S
G
F
F
S
K
V
E
K
K
-
Y
N
S
-----------------------------------
I
F
I
T
D
D
L
D
A
----------
M
E
K
I
---
S
C
-
L
V
------------
K
S
D
I
-
T
R
-
N
W
R
W
A
D
I
C
G
E
L
R
T
N
R
M
I
L
K
K
E
L
E
-
S
R
G
V
K
F
R
E
L
I
N
S
I
R
I
S
Y
S
-
I
S
L
M
K
T
--
G
E
F
K
I
K
Q
I
A
Y
Q
S
G
F
-----------------
A
S
V
S
Y
F
S
T
V
F
K
S
T
M
N
---
V
A
P
S
E
Y
L
F
M
L
------------
44
Fugue
76.82
12%
-46
- C2 -
3GBG
1
TCPN_VIBC3
A:
[4-273]
-----------------------------------------------------------------------KKS
F
Q
T
N
V
Y
R
M
S
K
F
D
T
Y
I
F
N
N
L
Y
I
N
D
Y
K
M
F
W
I
D
S
G
-----------
I
A
K
L
I
D
K
------------
N
C
L
--
V
S
Y
E
I
N
S
S
S
I
I
L
L
K
K
N
S
I
Q
R
F
----
S
---------------
L
T
S
L
S
--
D
E
N
I
N
V
S
V
I
T
I
S
D
S
-------
F
I
R
-------
S
L
K
S
Y
--
I
L
G
N
K
D
L
L
L
W
N
----------------
C
E
H
N
D
I
A
V
---
L
S
E
V
V
N
G
F
R
E
I
--
N
Y
S
--
D
E
F
L
K
V
F
F
S
G
-
F
F
S
K
------------------------
V
E
K
K
Y
N
S
I
F
I
T
D
D
L
D
---
A
----------
M
E
K
I
---
S
C
-
L
V
------------
K
S
D
I
-
T
R
-
N
W
R
W
A
D
I
C
G
E
L
R
T
N
R
M
I
L
K
K
E
L
E
S
-
R
G
V
K
F
R
E
L
I
N
S
I
R
I
S
Y
S
-
I
S
L
M
K
T
--
G
E
F
K
I
K
Q
I
A
Y
Q
S
G
F
-----------------
A
S
V
S
Y
F
S
T
V
F
K
S
T
M
N
---
V
A
P
S
E
Y
L
F
M
L
-
T
GV--------
20
HHSearch
76.75
24%
-75
- C2 -
3W6V
2
?
A:
[37-140]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
D
P
----------
L
A
E
V
---
V
A
-
W
A
------------
L
E
H
L
-
H
E
-
Q
F
D
V
E
T
L
A
A
R
A
Y
M
S
R
R
T
F
D
R
R
F
R
S
L
T
G
S
A
P
L
Q
W
L
I
T
Q
R
V
L
Q
A
-
Q
R
L
L
E
T
--
S
D
Y
S
V
D
E
V
A
G
R
C
G
F
-----------------
R
S
P
V
A
L
R
G
H
F
R
R
Q
L
G
---
S
S
P
A
A
Y
R
A
A
Y
------------
3
PsiBlast_PDB
76.73
26%
-84
- C2 -
3W6V
2
?
A:
[40-133]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
E
V
---
V
A
-
W
A
------------
L
E
H
L
-
H
E
-
Q
F
D
V
E
T
L
A
A
R
A
Y
M
S
R
R
T
F
D
R
R
F
R
S
L
T
G
S
A
P
L
Q
W
L
I
T
Q
R
V
L
Q
A
-
Q
R
L
L
E
T
--
S
D
Y
S
V
D
E
V
A
G
R
C
G
F
-----------------
R
S
P
V
A
L
R
G
H
F
R
R
Q
L
G
---
S
S
P
-------------------
25
HHSearch
76.69
27%
-82
- C2 -
2K9S
-
A:
[3-106]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
R
----------
V
R
E
A
---
C
Q
-
Y
I
------------
S
D
H
L
-
A
D
S
N
F
D
I
A
S
V
A
Q
H
V
C
L
S
P
S
R
L
S
H
L
F
R
Q
Q
L
G
I
S
V
L
S
W
R
E
D
Q
R
I
S
Q
A
-
K
L
L
L
S
T
--
T
R
M
P
I
A
T
V
G
R
N
V
G
F
-----------------
D
D
Q
L
Y
F
S
R
V
F
K
K
C
T
G
---
A
S
P
S
E
F
R
A
G
C
------------
24
HHSearch
75.57
29%
-76
- C2 -
3OOU
1
?
A:
[4-107]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
P
I
----------
I
Q
N
V
---
L
S
-
Y
I
------------
T
E
H
F
-
S
E
-
G
M
S
L
K
T
L
G
N
D
F
H
I
N
A
V
Y
L
G
Q
L
F
Q
K
E
M
G
E
H
F
T
D
Y
L
N
R
Y
R
V
N
Y
A
-
K
E
E
L
L
Q
--
T
K
D
N
L
T
I
I
A
G
K
S
G
Y
-----------------
T
D
M
A
Y
F
Y
R
Q
F
K
K
H
T
G
---
E
T
P
N
R
Y
R
K
I
H
------------
4
PsiBlast_PDB
74.74
30%
-83
- C2 -
4FE7
-
XYLR_ECOLI
A:
[307-402]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
I
Q
A
---
M
H
-
Y
I
------------
R
N
H
A
-
C
K
-
G
I
K
V
D
Q
V
L
D
A
V
G
I
S
R
S
N
L
E
K
R
F
K
E
E
V
G
E
T
I
H
A
M
I
H
A
E
K
L
E
K
A
-
R
S
L
L
I
S
--
T
T
L
S
I
N
E
I
S
Q
M
C
G
Y
-----------------
P
S
L
Q
Y
F
Y
S
V
F
K
K
A
Y
D
---
T
T
P
K
E
-----------------
2
PsiBlast_PDB
74.64
28%
-88
- C2 -
2K9S
-
A:
[5-101]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
R
E
A
---
C
Q
-
Y
I
------------
S
D
H
L
-
A
D
S
N
F
D
I
A
S
V
A
Q
H
V
C
L
S
P
S
R
L
S
H
L
F
R
Q
Q
L
G
I
S
V
L
S
W
R
E
D
Q
R
I
S
Q
A
-
K
L
L
L
S
T
--
T
R
M
P
I
A
T
V
G
R
N
V
G
F
-----------------
D
D
Q
L
Y
F
S
R
V
F
K
K
C
T
G
---
A
S
P
S
E
-----------------
27
HHSearch
73.99
30%
-75
- C2 -
3LSG
1
?
A:
[3-103]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
----------
K
E
L
I
---
Q
N
-
I
I
------------
E
E
S
Y
T
D
S
-
Q
F
T
L
S
V
L
S
E
K
L
D
L
S
S
G
Y
L
S
I
M
F
K
K
N
F
G
I
P
F
Q
D
Y
L
L
Q
K
R
M
E
K
A
-
K
L
L
L
L
T
--
T
E
L
K
N
Y
E
I
A
E
Q
V
G
F
-----------------
E
D
V
N
Y
F
I
T
K
F
K
K
Y
Y
Q
---
I
T
P
K
Q
Y
R
E
--------------
7
PsiBlast_PDB
73.73
32%
-78
- C2 -
3LSG
1
?
A:
[6-100]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
----------
I
Q
N
I
---
I
E
---------------
E
S
Y
T
-
D
S
-
Q
F
T
L
S
V
L
S
E
K
L
D
L
S
S
G
Y
L
S
I
M
F
K
K
N
F
G
I
P
F
Q
D
Y
L
L
Q
K
R
M
E
K
A
-
K
L
L
L
L
T
--
T
E
L
K
N
Y
E
I
A
E
Q
V
G
F
-----------------
E
D
V
N
Y
F
I
T
K
F
K
K
Y
Y
Q
---
I
T
P
K
Q
-----------------
6
PsiBlast_PDB
73.45
24%
-88
- C2 -
3OIO
2
?
A:
[6-104]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
P
K
----------
L
T
E
A
---
V
S
-
L
M
------------
E
A
N
I
-
E
E
-
P
L
S
T
D
D
I
A
Y
Y
V
G
V
S
R
R
Q
L
E
R
L
F
K
Q
Y
L
G
T
V
P
S
K
Y
Y
L
E
L
R
L
N
R
A
-
R
Q
L
L
Q
Q
--
T
S
K
S
I
V
Q
I
G
L
A
C
G
F
-----------------
S
S
G
P
H
F
S
S
T
Y
R
N
H
F
N
---
I
T
P
R
E
-----------------
23
HHSearch
72.06
24%
-76
- C2 -
3OIO
2
?
A:
[6-109]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
P
K
----------
L
T
E
A
---
V
S
-
L
M
------------
E
A
N
I
-
E
E
-
P
L
S
T
D
D
I
A
Y
Y
V
G
V
S
R
R
Q
L
E
R
L
F
K
Q
Y
L
G
T
V
P
S
K
Y
Y
L
E
L
R
L
N
R
A
-
R
Q
L
L
Q
Q
--
T
S
K
S
I
V
Q
I
G
L
A
C
G
F
-----------------
S
S
G
P
H
F
S
S
T
Y
R
N
H
F
N
---
I
T
P
R
E
E
R
A
Q
R
------------
46
Fugue
71.90
15%
-36
* C1 *
4DNH
2
?
A:
[2-387]
--------------------------------------------------------------------------
L
V
S
I
D
L
P
I
E
G
R
L
A
R
Y
D
L
T
---
G
R
P
V
P
F
N
S
R
D
A
K
--
A
F
S
R
V
A
F
A
A
A
H
V
V
A
D
PLADNDPWL
A
P
A
I
D
W
--
E
R
T
L
A
F
R
H
R
L
W
D
L
G
-
L
G
V
A
E
S
M---
D
TAQRGMGLG
W
P
E
A
R
E
L
I
R
R
S
--
L
A
E
A
R
G
R
P
D
A
L
I
A
C
G
A
G
TDHL
A
P
G
-------
P
D
V
S
I
--
D
D
I
L
A
A
Y
E
S
Q
I
E
---
A
I
E
A
E
GGR
I
I
L
M
A
S
R
A
L
A
A
A
AKG
P
E
D
Y
I
R
V
Y
D
R
V
--
L
S
Q
V
K
E
P
V
I
I
H
W
L
G
E
M
F
D
P
A
LEGYWGNAD
H
M
A
A
M
K
T
C
L
D
V
L
E
A
H
A
A
K
V
D
G
I
K
I
S
L
L
S
K
E
K
E
I
V
M
---------
R
R
Q
L
PKG
V
R
M
Y
T
GDDFN
Y
A
E
L
I
A
G
D
E
E
G
-
H
S
-
D
A
L
L
G
I
F
D
A
I
A
P
V
A
S
A
A
L
E
A
L
G
S
G
R
--
N
G
E
F
F
E
L
L
E
P
T
V
P
L
S
-
R
H
I
F
K
A
--
P
T
R
F
Y
K
T
G
V
V
F
L
A
Y
L
N
GLQDHFVMIGGQQSA
R
S
L
V
H
L
A
E
L
F
R
L
A
D
K
A
GA
L
A
D
P
E
L
A
T
A
R
M
R
R
V
L
A
M
H
GV--
8
PsiBlast_PDB
71.30
25%
-79
- C2 -
1XS9
2
MARA_ECOLI
A:
[14-109]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
T
----------
I
H
S
I
---
L
D
-
W
I
------------
E
D
N
L
-
E
S
-
P
L
S
L
E
K
V
S
E
R
S
G
Y
S
K
W
H
L
Q
R
M
F
K
K
E
T
G
H
S
L
G
Q
Y
I
R
S
R
K
M
T
E
I
-
A
Q
K
L
K
E
--
S
N
E
P
I
L
Y
L
A
E
R
Y
G
F
-----------------
E
S
Q
Q
T
L
T
R
T
F
K
N
Y
F
D
---
V
P
P
-------------------
39
Fugue
71.15
22%
-52
* C2 *
1BL0
2
MARA_ECOLI
A:
[9-124]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
I
T
----------
I
H
S
I
---
L
D
-
W
I
------------
E
D
N
L
-
E
S
-
P
L
S
L
E
K
V
S
E
R
S
G
Y
S
K
W
H
L
Q
R
M
F
K
K
E
T
G
H
S
L
G
Q
Y
I
R
S
R
K
M
T
E
I
-
A
Q
K
L
K
E
--
S
N
E
P
I
L
Y
L
A
E
R
Y
G
F
-----------------
E
S
Q
Q
T
L
T
R
T
F
K
N
Y
F
D
---
V
P
P
H
K
Y
R
M
T
N
-
M
QGESRFLHPL
42
Fugue
70.93
15%
-30
- C2 -
4FE7
1
XYLR_ECOLI
A:
[21-409]
MFT
K
R
H
R
I
T
L
L
F
N
ANK
A
Y
D
R
Q
V
V
E
G
V
G
E
Y
L
Q
A
S
QSEWDIFIEEFRWLGD
G
V
I
A
DFDD
K
Q
I
E
Q
A
L
ADVD
V
P
I
V
G
V
G
G
S
Y
H
L
A
E
S
Y
P
P
V
H
Y
I
A
T
D
N
Y
A
L
V
E
S
A
F
L
H
L
K
E
K
G
V
N
R
F
A
F
Y
G
L
P
E
S
S
G
K
------------
R
W
A
--
T
E
R
E
Y
A
F
R
Q
L
V
A
E
E
-
K
Y
R
G
V
V
Y
Q
G
L
E
---------------
T
A
P
E
N
--
W
Q
H
A
Q
N
R
L
A
D
W
L
Q
T
-------
L
P
P
Q
T
G
I
I
A
V
T
D
A
R
A
--
R
H
I
L
Q
V
C
E
H
L
H
I
PVP
E
K
L
C
----
V
I
G
-
I
D
N
E
E
L
T
R
---
Y
L
S
R
V
A
L
S
S
V
A
Q
G
A
R
Q
M
G
Y
Q
A
A
K
L
L
H
R
L
-
L
D
K
E
------------------------
E
M
P
L
Q
R
I
L
V
P
P
V
R
V
I
E
R
R
S
TDYRSLTD
P
A
V
I
Q
A
---
M
H
-
Y
I
------------
R
N
H
A
-
C
K
-
G
I
K
V
D
Q
V
L
D
A
V
G
I
S
R
S
N
L
E
K
R
F
K
E
E
V
G
E
T
I
H
A
M
I
H
A
E
K
L
E
K
A
-
R
S
L
L
I
S
--
T
T
L
S
I
N
E
I
S
Q
M
C
G
Y
-----------------
P
S
L
Q
Y
F
Y
S
V
F
K
K
A
Y
D
---
T
T
P
K
E
Y
R
D
V
N
-
S
E---------
9
PsiBlast_PDB
70.32
25%
-68
- C2 -
1BL0
2
MARA_ECOLI
A:
[11-106]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
T
----------
I
H
S
I
---
L
D
-
W
I
------------
E
D
N
L
-
E
S
-
P
L
S
L
E
K
V
S
E
R
S
G
Y
S
K
W
H
L
Q
R
M
F
K
K
E
T
G
H
S
L
G
Q
Y
I
R
S
R
K
M
T
E
I
-
A
Q
K
L
K
E
--
S
N
E
P
I
L
Y
L
A
E
R
Y
G
F
-----------------
E
S
Q
Q
T
L
T
R
T
F
K
N
Y
F
D
---
V
P
P
-------------------
5
PsiBlast_PDB
69.55
30%
-67
- C2 -
4FE4
-
XYLR_ECOLI
A:
[287-382]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
I
Q
A
---
M
H
-
Y
I
------------
R
N
H
A
-
C
K
-
G
I
K
V
D
Q
V
L
D
A
V
G
I
S
R
S
N
L
E
K
R
F
K
E
E
V
G
E
T
I
H
A
M
I
H
A
E
K
L
E
K
A
-
R
S
L
L
I
S
--
T
T
L
S
I
N
E
I
S
Q
M
C
G
Y
-----------------
P
S
L
Q
Y
F
Y
S
V
F
K
K
A
Y
D
---
T
T
P
K
E
-----------------