@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0176: (2016-03-12 )
LNIMIALIPALLWGTVPLIITKFGGSTRQQTMGMTLGALTFAVIVFFFTDPVYTLKTVGISFITGCLWTVGQMFQLQAFKIIGVSKAMPISTGMQLVGTTLCGVILFHEWDTTLRIILGFIALALIVGGIFLTSYAEKEEDGTNALKQGLITLFISACGYVGLVVLIQGFKIDGINAILPQAIGMVISALIMTHSGGTEKRFNKRTLLLTIPGVIWAAGNVAMVHANQLVGVATGFSLSQLGVVISTIGGIILLKEKKTQKEMLFVIVGVVLVVLGGILIGVAKGA
Atome Classification :
(20 SA)
-----.........10........20----........30.....-------...----------40........50...--.....60...-----....-----.70.....--...80........90.........-100--------.......110.......120-----.-......130.......140-----------.......-.----.150.....-------...160.......170-----------......-.180....-..-.190------.-....-.-...200.....--------..210-----------...-----....220------.......230......-.---------.-240.......250-.......260.--.--------------.....270.....-..280..-..---------------------------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----LN
I
M
I
A
L
I
P
A
L
L
WGT
V
P
L
I
I
T
----KFGGSTR
Q
Q
TM
G
M
T
L
-------
G
A
L
----------
T
F
A
V
I
V
F
F
FTDP
V
Y
T
--
L
K
T
V
G
I
S
F
I
T
-----
G
C
L
W
-----
T
V
G
Q
M
F
Q
L
--
Q
A
F
K
I
I
GVSKAMPI-ST
G
M
Q
L
V
G
T
-
T
L
C
--------
G
V
I
L
F
HEW
D
T
T
L
R
I
I
L
G
F
I
A
-----
L
-
A
L
I
V
G
G
I
F
L
T
S
Y
AEKEE-------------D
G
T
N
A
L
K
-
Q
----
G
L
-
I
T
L
F
I
S
-------
A
C
G
Y
V
G
L
V
V
L
IQGFKI-----------D
G
I
N
A
I
-
L
P
Q
A
I
G
M
V
-
I
S
-
A
L
--------
I
-MTHS-G-GTEKRFNK
R
T
L
--------
L
L
TIP-----------G
V
I
-----WAAG
N
V
A
------
M
V
HAN
Q
L
V
G-VATGF
S
-
L
---------
S
-
Q
L
G
V
V
I
S
TIG
G
I
I
-
L
L
KEKKT
Q
K
E
M
--
L
--------------
F
V
I
V
G
V
V
L
V
V
L
G
G
-
I
L
I
GVAK-GA---------------------------------------------------------------------
31
Fugue
85.76
14%
-138
- C3 -
4RKK
5
EPM2A_HUMAN
A:
[1-328]
G
S
H
M
R
F
R
F
G
V
V
V
P
P
A
V
A
G
A
R
P
E
L
L
V
V
GSRP
E
L
G
R
W
E
P
R
G
A
V
R
L
R
P
AGTAAGD
G
A
L
----------
A
L
Q
E
P
G
L
W
L
G
E
V
E
L
A
AR
V
D
T
F
W
Y
K
F
L
K
R
E
PG
G
E
L
S
W
E
G
NGP
H
H
D
R
C
C
T
Y
--
N
E
N
N
L
V
D
G
V
Y
C
L
P
I
-
G
H
W
I
E
A
T
G
H
-
T
---------------
N
E
M
K
H
T
T
D
F
Y
F
N
I
A
G
H
Q
A
M
H
Y
-
S
R
I
L
P
N
I
W
L
G
S
C
P
R
Q
V
E
-------------
H
V
T
I
K
L
K
-
H
----
E
L
G
I
T
A
V
M
N
-------
F
Q
T
E
W
D
I
V
Q
N
S
S
G
C
N
R
-----------
Y
P
-
E
P
M
-
T
P
D
T
M
I
K
L
-
Y
R
-
E
E
--------
G
-
L
A
Y
I
-
W
-
M
P
T
P
D
M
S
T
E
G
R
--------
V
Q
M
L
P
-----------
Q
A
V
-----
C
L
L
H
A
L
L
E
K
GHI
V
Y
V
H
S
N
A
G
V
G
-
R
S
T
A
A
V
-
C
---------
G
-
W
L
Q
Y
V
M
G
-
W
N
L
R
K
-
V
Q
Y
F
L
M
A
K
R
P
A
--
V
--------------
Y
I
D
E
E
A
L
A
R
A
Q
E
D
-
F
F
Q
K
F
G
K
-
V
R
---------------------------------------------------------------------
28
Fugue
72.74
13%
-126
- C2 -
1SUU
-
GYRA_BORBU
A:
[506-809]
-----
E
N
I
V
V
M
L
T
K
K
---
G
F
L
K
R
L
S
Q
----
N
E
Y
K
L
Q
G
T
G
G
K
G
L
S
S
-------
F
D
L
----------
N
D
-------
G
D
E
I
V
I
--
A
L
C
V
N
T
H
D
Y
L
-----
F
M
I
S
-----
N
E
G
K
L
Y
L
I
--
N
A
Y
E
I
K
D
Q
N
I
S
E
L
I
-
N
L
G
D
---
Q
E
-
E
I
L
--------
T
I
K
N
S
K
D
L
T
D
D
A
Y
L
L
L
T
T
------------
A
S
G
K
I
A
R
F
E
S
T
D
F
K
-------------
A
G
V
I
V
I
K
-
L
N
D
KD
F
V
-
T
S
A
E
I
V
F
K
D
E
K
V
I
C
L
S
K
K
G
S
A
F
I
F
N
S
R
D
V
RLTNRGT----
Q
G
V
C
G
M
-
K
L
K
E
G
D
L
F
-
V
K
-
V
L
S
VKENP
Y
L
L
-
I
V
S
E
-
N
-
G
Y
G
K
R
L
N
M
S
K
I
--------
S
E
L
K
R
-----------
G
--------
A
T
G
Y
T
S
------
Y
K
K
S
D
K
K
A
G
-
S
V
V
D
A
I
-
A
V
S
-------
E
-
D
D
E
I
L
L
V
S
K
R
S
K
A
-
L
R
T
V
A
G
K
V
S
E
Q
--
G
--------------
K
D
A
R
G
I
Q
V
L
F
L
D
N
D
S
L
V
S
V
S
K
-
F
I
---------------------------------------------------------------------
25
Fugue
66.57
15%
-121
* C4 *
4PW1
1
?
A:
[16-252]
---------------------
N
L
L
Y
L
----
N
S
G
E
E
L
N
L
Y
P
W
N
L
Y
T
-------
G
Q
E
----------
Q
E
-----
L
F
E
E
E
I
V
S
--
F
A
A
N
S
V
R
I
L
G
-----
G
G
S
W
-----
T
D
E
E
L
Y
P
L
--
I
K
F
R
Y
S
G
---------
Q
D
L
R
F
L
K
D
M
A
--------------
L
T
E
K
D
G
R
-----
R
Y
L
V
-----
N
M
A
L
D
P
N
G
L
C
Y
F
S
Y
V
N
Q
D
E
-------------
R
E
A
T
A
D
E
M
D
------------------------
Q
A
L
G
K
L
Q
E
D
W
E
K
-----------
F
L
S
D
P
L
-
P
K
T
D
N
A
F
Y
M
F
F
M
R
C
--------
Q
M
L
S
D
Q
M
R
-
K
E
Q
Y
S
D
Y
I
G
D
N
--------
L
Y
T
I
W
-----------
E
L
V
-----
L
K
S
E
F
T
S
------
L
S
Y
D
N
H
I
Y
A
M
Y
S
N
D
G
G
-
T
---------
S
M
V
L
--
I
Y
S
P
I
E
E
--------------------------------
R
F
V
G
F
S
L
K
Y
-----------------------------------------------------------------------------------
30
Fugue
58.44
12%
-120
* C3 *
4QUV
1
?
A:
[23-427]
--F
S
W
L
V
L
M
I
A
L
P
P
L
V
Y
Y
--
L
W
I
C
V
T
----
Y
Y
Q
G
E
L
V
F
T
S
D
A
A
A
W
-------
R
R
F
W
SHVAPPT
W
H
A
A
G
L
Y
A
A
W
F
L
G
Q
A
A
L
--
Q
V
W
A
P
G
P
T
V
Q
-----
G
M
K
L
-----
P
D
G
S
R
L
D
Y
--
R
M
N
G
I
F
S
F
L
F
T
L
A
V
-
V
F
G
L
V
T
M
G
W
--
L
D
--------
A
T
V
L
Y
D
Q
L
G
P
L
L
T
V
V
N
I
F
T
F
-----
V
-
F
A
G
F
L
Y
F
W
G
P
F
Y
D
Y
F
M
G
-------------
T
A
L
N
P
R
I
-
G
----
S
L
-
D
L
K
L
F
C
-------
E
A
R
P
G
M
I
F
W
L
L
M
N
L
S
M
-----------
A
A
K
Q
Y
E
-
L
H
G
T
V
T
V
P
-
M
L
-
L
V
--------
V
-
G
F
Q
S
-
F
-
Y
L
I
D
Y
F
I
H
E
E
A
--------
V
L
T
T
W
-----------
D
I
K
HEKFG
W
M
L
C
W
G
D
------
L
V
W
L
P
F
T
Y
T
-
L
Q
A
Q
Y
L
-
V
HHT
H
D
L
P
V
W
G
-
I
I
A
I
V
A
L
N
L
A
G
Y
A
-
I
F
R
G
A
N
I
Q
K
H
H
--
F
R
R
DPNRIVWGKP
A
K
Y
I
K
T
K
Q
G
S
L
L
L
T
S
-
G
W
W
G
I
A
R
-
H
M
N
Y
F
G
D
L
M
I
A
L
S
W
C
LPAAFGSPIPY
F
H
I
V
Y
F
T
I
L
L
L
H
R
E
K
R
D
D
A
M
C
L
A
K
YG
E
D
W
L
Q
Y
R
K
K
V
PWRIVPKIY
26
Fugue
57.26
16%
-109
- C1 -
3NSW
1
?
A:
[1-106]
------------------------------------------
G
S
H
-------
M
E
Y
----------
C
P
K
M
L
S
E
I
R
Q
E
D
I
N
D
--
V
E
T
V
A
Y
V
T
V
T
-----
G
--------
K
T
A
R
S
Y
N
L
--
Q
Y
W
R
L
Y
D
V
P
K
T
A
P
S
-
Q
W
P
S
F
G
T
L
R
-
D
D
C
--------
G
N
I
---
Q
L
T
A
D
T
D
Y
V
L
G
C
K
S
-----
G
-
N
---
Q
D
C
F
V
K
L
H
D
G
L
S
Q
-------------
K
E
K
D
L
L
K
-
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
Fugue
56.50
15%
-90
- C4 -
5COZ
1
?
A:
[12-358]
----D
L
N
D
Y
E
N
V
L
N
S
L
D
E
E
Q
I
G
K
L
P
Q
----
N
I
K
C
V
V
N
D
K
---------------
L
----------
N
I
D
S
E
I
N
I
W
D
A
T
S
Y
Y
--
V
K
S
G
K
V
K
A
I
N
-----
F
S
E
------
N
K
D
K
C
Y
D
L
M
E
K
L
A
K
A
I
N
L
N
K
D
V
C
V
-
Q
S
H
R
S
E
N
G
N
-
E
I
Y
L
W
D
NNYTQ
D
S
I
A
I
R
N
D
S
A
L
A
E
T
H
D
G
K
L
A
-----
V
-
S
A
S
K
F
G
T
Y
Y
S
P
F
N
D
K
D
K
FRTDKQLMFMS
A
E
E
A
E
E
L
A
V
-
K
----
T
A
-
K
E
L
E
I
N
-------
V
C
E
K
N
E
L
Y
V
L
D
D
K
N
T
L
IFPEDDTD
K
Q
N
D
T
Y
V
F
F
M
F
P
D
V
Y
G
I
P
-
Y
S
-
R
C
--------
P
-
E
N
E
A
-
L
T
G
Y
A
N
Q
E
N
H
L
V
I
A
M
D
EKGIS
F
L
D
I
P
P
L
Y
D
W
VETT
E
T
G
E
I
-----
L
H
P
S
S
I
L
------
S
K
E
V
D
K
L
K
K
-
Y
V
T
S
G
----------------
D
I
E
V
S
E
I
S
L
E
Y
M
L
F
A
D
K
N
E
T
Y
D
I
K
P
V
--------------
W
V
V
Y
Y
Y
Q
N
Q
L
V
T
G
-
E
N
S
Y
T
Q
K
M
A
L
Y
D
V
Y
DAYTGEEYRIQ------------------------------------------------------
11
PsiBlast_PDB
51.13
28%
-63
- C5 -
4AS4
3
IMPA1_HUMAN
A:
[155-206]
-------------------
T
K
S
L
L
V
T
----
E
L
G
S
S
R
T
P
E
T
V
R
M
V
L
-------
S
N
M
----------
E
K
-----
L
F
C
I
P
V
H
G
--
I
R
S
V
G
T
A
A
V
N
-----
M
C
L
V
-----
A
T
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
50.24
28%
-72
- C5 -
1IME
-
IMPA1_HUMAN
A:
[155-206]
-------------------
T
K
S
L
L
V
T
----
E
L
G
S
S
R
T
P
E
T
V
R
M
V
L
-------
S
N
M
----------
E
K
-----
L
F
C
I
P
V
H
G
--
I
R
S
V
G
T
A
A
V
N
-----
M
C
L
V
-----
A
T
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
49.17
28%
-68
- C5 -
2HHM
-
IMPA1_HUMAN
A:
[154-205]
-------------------
T
K
S
L
L
V
T
----
E
L
G
S
S
R
T
P
E
T
V
R
M
V
L
-------
S
N
M
----------
E
K
-----
L
F
C
I
P
V
H
G
--
I
R
S
V
G
T
A
A
V
N
-----
M
C
L
V
-----
A
T
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
49.05
28%
-70
- C5 -
1AWB
2
IMPA1_HUMAN
A:
[154-205]
-------------------
T
K
S
L
L
V
T
----
E
L
G
S
S
R
T
P
E
T
V
R
M
V
L
-------
S
N
M
----------
E
K
-----
L
F
C
I
P
V
H
G
--
I
R
S
V
G
T
A
A
V
N
-----
M
C
L
V
-----
A
T
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
48.26
28%
-61
- C5 -
1IMA
1
IMPA1_HUMAN
A:
[155-206]
-------------------
T
K
S
L
L
V
T
----
E
L
G
S
S
R
T
P
E
T
V
R
M
V
L
-------
S
N
M
----------
E
K
-----
L
F
C
I
P
V
H
G
--
I
R
S
V
G
T
A
A
V
N
-----
M
C
L
V
-----
A
T
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
47.83
28%
-64
- C5 -
1IMD
-
IMPA1_HUMAN
A:
[155-206]
-------------------
T
K
S
L
L
V
T
----
E
L
G
S
S
R
T
P
E
T
V
R
M
V
L
-------
S
N
M
----------
E
K
-----
L
F
C
I
P
V
H
G
--
I
R
S
V
G
T
A
A
V
N
-----
M
C
L
V
-----
A
T
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
47.38
28%
-73
- C5 -
1IMF
-
IMPA1_HUMAN
A:
[155-206]
-------------------
T
K
S
L
L
V
T
----
E
L
G
S
S
R
T
P
E
T
V
R
M
V
L
-------
S
N
M
----------
E
K
-----
L
F
C
I
P
V
H
G
--
I
R
S
V
G
T
A
A
V
N
-----
M
C
L
V
-----
A
T
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
47.36
28%
-63
- C5 -
1IMC
-
IMPA1_HUMAN
A:
[155-206]
-------------------
T
K
S
L
L
V
T
----
E
L
G
S
S
R
T
P
E
T
V
R
M
V
L
-------
S
N
M
----------
E
K
-----
L
F
C
I
P
V
H
G
--
I
R
S
V
G
T
A
A
V
N
-----
M
C
L
V
-----
A
T
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
46.14
31%
-105
- C- -
1AAT
-
AATC_CHICK
A:
[286-332]
--------------------------------------------------------------------------------------------------------------------
Q
M
E
K
I
V
R
T
T
W
S
N
P
P
-
S
Q
G
A
R
I
V
A
T
-
T
L
T
--------
S
P
Q
L
F
A
E
W
K
D
N
V
K
T
M
A
D
R
V
L
-----
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
46.10
28%
-69
- C5 -
1IMB
1
IMPA1_HUMAN
A:
[155-206]
-------------------
T
K
S
L
L
V
T
----
E
L
G
S
S
R
T
P
E
T
V
R
M
V
L
-------
S
N
M
----------
E
K
-----
L
F
C
I
P
V
H
G
--
I
R
S
V
G
T
A
A
V
N
-----
M
C
L
V
-----
A
T
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
41.37
12%
-115
- C- -
3B5D
1
EMRE_ECOLI
A:
[37-105]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
I
C
-----
Y
C
A
S
F
W
L
------
L
A
Q
T
L
A
Y
I
P
-
T
G
I
A
Y
A
I
W
---------
S
-
G
V
G
I
V
L
I
S
L
L
S
W
G
-
F
F
G
Q
R
L
D
L
P
A
I
--------------------
I
G
M
M
L
I
C
A
G
V
-
L
I
I
N
L
L
S
------------------------------------------------------------------------
17
HHSearch
39.31
18%
-165
- C- -
3B5D
1
EMRE_ECOLI
A:
[29-105]
------------------------------------------------------------------------------------
R
L
W
P
S
V
G
T
-----
I
I
C
Y
-----
C
A
S
F
W
L
L
A
--
Q
T
L
A
Y
I
P
T
G
I
A
Y
A
I
W
S
G
-
V
G
I
V
L
I
-
S
L
L
--------
S
W
G
F
F
G
Q
R
L
D
L
P
----
A
I
I
G
-----
M
-
M
L
I
C
A
G
V
L
I
I
N
L
L
S
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
33.52
31%
22
- C5 -
2CST
1
AATC_CHICK
A:
[285-331]
--------------------------------------------------------------------------------------------------------------------
Q
M
E
K
I
V
R
T
T
W
S
N
P
P
-
S
Q
G
A
R
I
V
A
T
-
T
L
T
--------
S
P
Q
L
F
A
E
W
K
D
N
V
K
T
M
A
D
R
V
L
-----
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
25.53
21%
277
- C5 -
2JO1
-
PLM_HUMAN
A:
[23-36]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
A
G
I
L
F
I
L
G
I
-
L
I
V
L
---------------------------------------------------------------------------