@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0183: (2016-03-12 )
MDASTSFAILPSNVKQKTAFERKVNQVKAASWTNNCLTGTLDIGQFSCYFVNEKIARVTVNPFGEVDLTPSIAAIHDNEKQAAKFTETNDCYELHFADKEVIVCKNPFQIIMKQAGKRIFQTEGLAINRDKEHQISIQSEPGTAIFGLGEKTGALNKAGSIISMWNTDVYSPHNKDTVELYQSIPFMIADTAKTTYGLFYDNSHRTEFDFQSFEEMYTVLAEGGQANLYIIFGEDVKEVVANYTDLTGKTPLPPKWSLGYHQSRYSYTSEEEVERIANTFKEKEIPLDCVFMDIHYMDDFRVFTFNPDTFPNGPELIARLREQNIDVVPIVDPGIKKDVDYSVYQEGIKNNYFCTKLEGSIYYGDVWPGVSAFPDFLSTTVQHWWGSLHKFYTDLGIRGIWNDMNEPSVFNESKTMDLDVVHNLDGKNVTHKEAHNLYGLYMSKATFEGLKRLVPNERPFSLTRAGYAGVQRYSAVWTGDNRSHWEHLEMSLPMIMNLGLSGVAFTGADVGGFSSDCTKEMLIRWTQAGAFLPYFRNHCVQDSIYQEPWAFGADAEKIVKQYIELRYAFLPYIYTEFQKTAESGLPLVRPLYMEFKDERDLIQVNDQFMLGENILVAPIVREGQAKRLVRLPKGLWFNYWTKEQFVGGDYIIADAPIDTMPIYIKAGTILPVGSSVQNTKETQELTLEVYLDSETATGYVYNDDGKSYQYESGAVSKTTLTATFKNGEVLINATHQGEANLQQKVTTIQVFGEKIDKITRAGI
Atome Classification :
(24 SA)
---------------------------------------.........10........20........30........40...---.....50........60.....-.-..70.......-.80........90........100.......110.-.-.-.....120...-.....----------.130-.......140--.......150-...---.---...--160-.....---....170-.......180......----.--190-.--.......200.......--210...-.-------------------------------------------------------------------------------------------------------------------------------------------------------...--.220-.......230.......240.......250.......260.......270.......280.......290....-----..--.300.......310-........320.......330......--.-----340--.........350......-.-360.......---------------------370-.........380...-..-..390.-.--------......400.......410-------------------------.--------------------------.--------------------..--------------------.-------------------.--------------------------.------------.-----------------420.----------...--.----..----------------..430.......440.......450.......460.......470..-..-...480.......490.......500.......510..--.------.-----------------------...520.......530.......540.......550--.---.--....--.560.......570.......580.......590.......600.......610.......620.......630..-..---...640..-----...-...650----........660.......670--------------------.---.......680-..--.--...-..690-.--.-.....700.......-710........720.......730....-.-.---..740.--........750--.......760.------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------------------------MDAST
S
F
A
ILPSNV
K
Q
K
T
A
F
E
R
K
V
N
Q
V
K
AASWTNN
C
L
T
G
T
L
DIG---
Q
F
S
C
Y
F
VNE
K
I
A
R
V
T
VNPFGEV-D-LTP
S
I
A
A
IHDN-
E
K
Q
A
AKFTETND
C
Y
E
L
H
FAD
K
E
V
I
V
CK
N
P
F
Q
I
-
I
M
-
K
-Q-AGK
R
I
F--QTE-G
L
A
IN----------RDK
E
-
H
Q
I
S
I
QSEPG--
T
A
I
F
G
LGEKT-GAL---N---KAG--
S
---
I
I
S
M
W---NTDVYSP-HN
K
D
T
V
E
L
Y
Q
SIP
F
M
I----A--DT--A--K
T
T
Y
G
L
F
YDNSHRTEF
D
--
F
-
Q
S
F
E
-
E
-------------------------------------------------------------------------------------------------------------------------------------------------------
M
Y
T
--
V
L
AE-GGQA
N
L
Y
I
I
FGE
D
V
K
E
V
V
A
NYTDLTGKTPLPPKWSLGYHQSRYSYT
S
E
E
E
V
E
R
I
A
N
T
F
K
EKEIP
L
D
C
V
F
M
D
I
H
Y
-----MD--
D
F
R
V
F
T
FNPDTFP--N
G
P
E
L
I
A
R
L
R
EQNI
D
V
V
PIVDPGIKKD--V-----
D
----
Y
S
V
Y
Q
E
G
IKNN
Y
F
C
T
KLE-
G
-
S
I
Y
YGDVWP
G
---------------------
V
---
S
A
F
P
D
F
L
S
T
T
V
Q
H
W
W
-
G
S
-
L
H
K
F
-
Y
-
T
--------
D
LGI
R
G
IWNDMNEPSVFN--------------------------E--------------------------S--------------------K
T
--------------------
M
-------------------
D
--------------------------
L
------------
D
-----------------
V
--
V
----------HNL--D----GK----------------NV
T
H
K
E
A
H
N
L
Y
G
L
Y
M
S
K
A
T
F
E
G
L
K
R
LVPNERPFS
L
T
R
A
G
YAG
V
Q
R
Y
S
-
A
V
-
W
TGDNR
S
H
W
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H
L
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M
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M
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M
NLGLSG
V
A
FTGADVGGF
S
--
S
------
D
-----------------------
C
T
K
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M
L
I
R
W
TQAGA
F
L
P
Y
F
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N
HCVQ
D
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YQEPWAFG--A---
D
--
A
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K
I
--
V
K
Q
Y
I
E
L
R
Y
A
F
L
P
Y
I
Y
T
E
F
Q
K
T
A
ESGLP
L
V
R
P
L
Y
M
E
FKDERDLIQVND
Q
F
MLGEN
I
L
V
A
P
IVREG
Q
A
K
R
L
V
RLPKG-
L
W
---
F
NYW
T
-
K
E-----QFV-GG
D
Y
I
-----
I
ADAPIDT
M
P
I
Y
I
KAG
T
I
L
P---------------------V---GSSVQNTKE--T
Q
--
E
--
L
T
L
-
E
V
Y
LD-S--E-TA
T
G
Y
V
YNDDGK
S
Y
Q
-Y-ESGA
V
S
K
T
T
L
T
A
T
FKN
G
E
V
L
-
I
N
ATH-Q-G---EA
N
--
L
--
Q
Q
K
V
T
T
I
Q
V
F
G
--
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K
I
D
K
I
TRAGI------------------------------------------
56
Fugue
94.60
25%
-71
- C3 -
4BA0
12
OL4AG_CELJU
A:
[35-817]
--------------------------------------------------------------
A
V
F
Y
K
E
H
K
L
R
N
D
G
L
V
I
T
T
N
Q
G
---
N
I
R
L
Q
F
K
S
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A
A
I
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L
Y
R
A
D
S
K
----
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L
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-
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--
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----
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--
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-----
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V
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--
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-
D
-------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
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--
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K
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----
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D
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K
A
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K
D
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G
-
Q
P
K
A
F
E
L
Y
F
G
---------------------
N
---
G
G
I
I
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V
F
S
K
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G
S
R
W
F
-
S
S
-
I
Y
K
D
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L
-
S
--------
K
Q
G
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A
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W
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G
D
L
G
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P
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M
H
P
--------------------------
E
---------------------------------------------------------------------------------------------------------------------------------
D
-----------------
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--
Q
----------
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--
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------------------------
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-----------------------
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F
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K
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D
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-----
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Y
Q
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-----
T
L
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D
L
H
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V
L
V
K
A
G
A
F
M
P
---------------------
Y
---
V
P
A
V
S
T
T
E
D
YR
S
D
--
S
--
L
E
I
-
H
Y
Y
A
D
-
A
SV
P
-
L
A
Q
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F
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-
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R
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D
L
L
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A
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-
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--
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--
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A
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T
L
V
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H
N
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D
Q
Y
Q
H
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D
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N
G
K
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I
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A
QADCASTPAL
A
C
Y
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QERR
Q
L
Q
L
V
F
T
W
G
R
E
A
L
N
L
R
L
H
K
36
HHSearch
91.92
27%
-64
* C3 *
3LPP
5
SUIS_HUMAN
A:
[113-851]
----------------------------------------------------------------------------------
V
---
L
F
T
T
Q
N
Q
T
P
N
R
F
R
F
K
I
T
D
P
N
N
R
R
Y
-
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V
P
H
-
Q
Y
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K
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F
------------
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----------
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--
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G
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---
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--
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----
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--
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--
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-------------------------------------------------------------------------------------------------------------------------------------------------------
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--
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RANGT
T
----
Y
A
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W
P
G
---------------------
L
---
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W
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N
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Q
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M
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S
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F
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--------------------------
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--------------------------
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--------------------
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T
KGCNVNKLN-----------
Y
-------------------
P
PFTPDILDKLMY--------------
S
------------
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-----------------
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--
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----------
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D
A-
V
----
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N
----------------
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-----------------------
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S
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A
-
I
W
---
Y
D
Y
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S
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G
A
-----
K
R
P
W
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K
Q
R
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-----
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M
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A
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L
H
L
R
G
G
Y
I
I
P
---------------------
I
---
Q
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T
A
--
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L
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N-
N
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T
A
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D
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T
--
T
L
A
F
Q
T
V
K
I
L
G
--
L
T
---------------------------------------------------
40
HHSearch
90.76
34%
-79
- C3 -
3NSX
3
?
A:
[41-658]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
A
F
T
Y
I
M
D
E
D
--
D
I
V
Y
G
L
G
E
S
N
-
R
G
I
---
N
---
K
R
G
--
Y
---
C
Y
I
S
N
---
C
T
D
D
P
I
H
--
T
E
D
K
R
S
L
Y
G
A
H
N
F
I
I
----
V
--
S
G
-----
K
T
T
F
G
L
F
F
D
Y
P
S
K
L
T
F
D
--
I
-
G
Y
T
R
M
D
-------------------------------------------------------------------------------------------------------------------------------------------------------
T
L
K
--
V
S
C
E
-
N
A
D
L
D
I
Y
V
I
E
G
E
N
A
Y
D
I
V
K
Q
F
R
R
V
I
G
R
S
Y
I
P
P
K
F
A
F
G
F
G
Q
S
R
W
G
Y
T
T
K
E
D
F
R
A
V
A
K
G
Y
R
E
N
H
I
P
I
D
M
I
Y
M
D
I
D
Y
-----
M
Q
--
D
F
K
D
F
T
V
N
E
K
N
F
P
--
D
F
P
E
F
V
K
E
M
K
D
Q
E
L
R
L
I
P
I
I
D
A
G
V
K
V
E
--
K
-----
G
----
Y
E
V
Y
E
E
G
V
K
N
N
Y
F
C
K
R
E
D
-
G
-
S
D
F
V
A
A
V
W
P
G
---------------------
D
---
T
H
F
P
D
M
L
N
P
E
A
R
K
W
F
-
G
D
-
K
Y
R
F
-
L
-
I
--------
D
Q
G
I
E
G
F
W
N
D
M
N
E
P
A
I
F
Y
--------------------------
S
--------------------------
S
--------------------
E
G
--------------------
L
A
E
A
K
E
F
A
G
E
F
A
K
DTEGKIH
P
--------------------------
W
------------
A
M
Q
A
K
M
K
D
I
VNS
P
E
D
Y
K
R
F
--
Y
----------
H
N
V
--
N
----
G
K
----------------
K
I
R
H
D
K
V
H
N
L
F
G
Y
N
M
T
R
A
A
G
E
A
F
E
R
I
D
P
E
K
R
F
L
M
F
S
R
S
S
Y
I
G
M
H
R
Y
G
-
G
I
-
W
M
G
A
N
K
S
W
W
S
H
I
L
L
N
L
K
M
L
P
S
L
N
M
C
G
F
M
Y
T
G
A
D
L
G
G
F
G
--
D
------
D
-----------------------
T
T
R
D
L
L
L
R
F
L
A
L
G
V
F
T
P
L
M
R
D
H
A
A
E
G
T
R
E
Q
E
C
Y
Q
F
E
--
N
-------
I
E
D
--
F
R
S
V
I
N
A
R
Y
R
L
V
P
Y
L
Y
S
E
Y
M
K
A
A
L
N
D
D
M
Y
F
K
P
L
G
F
V
Y
P
D
D
K
M
A
I
R
V
E
D
Q
L
M
L
G
N
E
I
M
I
A
P
V
Y
E
Q
N
A
R
G
R
Y
V
Y
L
P
E
E
M
K
F
---
I
K
F
M
P
-
D
G
S
I
S
E
E
V
L
E
-
K
G
-
V
H
-----
Y
V
D
V
A
L
N
E
V
P
L
F
I
R
S
G
K
C
I
P
---------------------
V
---
A
E
A
A
E
C
V
K
D
--
I
D
TE
N
--
M
Q
L
-
I
G
Y
E
-------
G
S
S
Y
T
L
Y
E
D
D
G
I
H
K
D
-
Y
-
D
K
K
--------------------------------------------------------------------------------------------------------
37
HHSearch
90.36
27%
-63
- C3 -
3TOP
1
MGA_HUMAN
A:
[88-854]
--------------------------------------------------------------------------------------
R
L
D
V
T
Y
H
K
N
E
M
L
Q
F
K
I
Y
D
P
N
K
N
R
Y
-
E
V
P
V
-
P
L
N
I
P
S
-----------
M
P
S
S
T
P
E
G
Q
L
Y
D
V
L
I
K
K
N
P
F
G
I
-
E
I
R
R
-
K
S
T
G
T
I
I
W
--
D
S
Q
-
L
L
G
F
T
----------
F
S
D
M
F
I
R
I
S
T
R
L
P
-
S
--
K
Y
L
Y
G
F
G
E
T
E
-
H
R
S
---
Y
---
R
R
D
--
L
E
W
H
T
W
G
M
F
---
S
R
D
Q
P
P
----
G
Y
K
K
N
S
Y
G
V
H
P
Y
Y
M
----
G
--
L
E
E-
D
--
G
S
A
H
G
V
L
L
L
N
S
N
A
M
D
V
T
--
F
-
Q
P
L
--
P
-------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
T
--
Y
R
T
T
-
G
G
V
L
D
F
Y
V
F
L
G
P
T
P
E
L
V
T
Q
Q
Y
T
E
L
I
G
R
P
V
M
V
P
Y
W
S
L
G
F
Q
L
C
R
Y
G
Y
Q
N
D
S
E
I
A
S
L
Y
D
E
M
V
A
A
Q
I
P
Y
D
V
Q
Y
S
D
I
D
Y
-----
M
E
--
R
Q
L
D
F
T
L
S
P
-
K
F
A
--
G
F
P
A
L
I
N
R
M
K
A
D
G
M
R
V
I
L
I
L
D
P
A
I
S
G
N
ET
Q
-----
P
----
Y
P
A
F
T
R
G
V
E
D
D
V
F
I
K
Y
P
N
D
G
-
D
I
V
W
G
K
V
W
P
D
FPDVVVNGSLD
W
D
S
Q
V
E
L
YR
A
Y
---
V
A
F
P
D
F
F
R
N
S
T
A
K
W
W
-
K
R
-
E
I
E
E
-
L
-
Y
N
NPQNPER
S
L
K
F
D
G
M
W
I
D
M
N
E
P
S
S
F
V
--------------------------
N
--------------------------
G
--------------------
A
V
SPGCRDASLNHPPY------
M
-------------------
P
--------------------------
H
LESRDRGLSS--
K
-----------------
T
--
L
----------
C
M
E
S
Q
Q
I
L
PD
G
S
----------------
L
V
Q
H
Y
N
V
H
N
L
Y
G
W
S
Q
T
R
P
T
Y
E
A
V
Q
E
V
-
T
G
Q
R
G
V
V
I
T
R
S
T
F
P
S
S
G
R
W
A
-
G
H
-
W
L
G
D
N
T
A
A
W
D
Q
L
K
K
S
I
I
G
M
M
E
F
S
L
F
G
I
S
Y
T
G
A
D
I
C
G
F
F
--
Q
------
D
-----------------------
A
E
Y
E
M
C
V
R
W
M
Q
L
G
A
F
Y
P
F
S
R
N
H
N
T
I
G
T
R
R
Q
D
P
V
S
W
D
--
V
---
A
--
F
V
N
I
--
S
R
T
V
L
Q
T
R
Y
T
L
L
P
Y
L
Y
T
L
M
H
K
A
H
T
E
G
V
T
V
V
R
P
L
L
H
E
F
V
S
D
Q
V
T
W
D
I
D
S
Q
F
L
L
G
P
A
F
L
V
S
P
V
L
E
R
N
A
R
N
V
T
A
Y
F
P
R
A
-
R
W
---
Y
D
Y
Y
T
-
G
V
-----
D
I
N
A
R
G
E
W
K
-----
T
L
P
A
P
L
D
H
I
N
L
H
V
R
G
G
Y
I
L
P
---------------------
W
---
Q
E
P
A
L
N
T
H
L
--
S
R
Q
K
F
--
M
G
F
-
K
I
A
L
D
-
D
E-
G
-
T
A
G
G
W
L
F
W
D
D
G
Q
S
I
D
-
T
Y
G
K
G
L
Y
Y
L
A
S
F
S
A
S
Q
N
--
T
M
Q
-
S
H
I
I
F
-
N
-
N
---
Y
I
T
GT
N
--
P
L
K
L
G
Y
I
E
I
W
G
--
V
G
---------------------------------------------------
59
Fugue
89.76
25%
-64
- C3 -
2QMJ
14
MGA_HUMAN
A:
[7-870]
VNELERINCIPDQPPT
K
A
T
C
D
Q
R
G
C
C
W
N
PQGAVSVPW
C
Y
Y
S
K
N
H
S
Y
H
V
E
G
N
L
V
N
T
N
A
G
F
T
A
R
L
K
N
L
P
S
S
P
V
F
G
S
----
N
V
D
N
V
---
L
L
T
A
E
Y
Q
T
S
N
R
F
H
F
K
L
T
D
Q
T
N
N
-
R
-
F
E
V
P
H
E
H
V
Q
S
F
-
S
G
N
----
A
A
A
S
L
T
Y
Q
V
E
I
S
R
Q
P
F
-----
S
I
K
V
-
T
R
-
R
-
S
-
N
N
R
V
L
F
--
D
S
S
-
I
G
P
L
L
----------
F
A
D
Q
-
F
L
Q
L
S
T
R
L
P
S
--
T
N
V
Y
G
L
G
E
H
V
-
H
Q
Q
YRH
D
---
M
N
W
--
K
---
T
W
P
I
F
---
N
R
D
T
T
P
N
-
G
N
G
T
N
--
L
Y
G
A
Q
T
F
F
L
----
C
LE
D
A
--
S
--
G
L
S
F
G
V
F
L
M
N
S
N
A
M
E
V
V
--
L
-
Q
P
-
A
-
P
-------------------------------------------------------------------------------------------------------------------------------------------------------
A
I
T
--
Y
R
T
I
-
G
G
I
L
D
F
Y
V
F
L
G
N
T
P
E
Q
V
V
Q
E
Y
L
E
L
I
G
R
P
A
L
P
S
Y
W
A
L
G
F
H
L
S
R
Y
E
Y
G
T
L
D
N
M
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V
V
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R
N
R
A
A
Q
L
P
Y
D
V
Q
H
A
D
I
D
Y
-----
M
D
--
E
R
R
D
F
T
Y
D
S
V
D
F
K
--
G
F
P
E
F
V
N
E
L
H
N
N
G
Q
K
L
V
I
I
V
D
P
A
I
S
N
N
--
S
SSSK-
P
----
Y
G
P
Y
D
R
G
S
D
M
K
I
W
V
N
S
S
D
-
G
V
T
P
L
I
G
E
V
W
P
G
---------------------
Q
---
T
V
F
P
D
Y
T
N
P
N
C
A
V
W
W
-
T
K
E
F
E
L
F
-
H
-
N
--------
Q
V
E
F
D
G
I
W
I
D
M
N
E
V
S
N
F
V
DGSVSGCSTNNLNNPPFTPRILDGYL
F
--------------------------
C
--------------------
K
T
--------------------
L
-------------------
C
--------------------------
M
------------
D
-----------------
A
--
V
----------
Q
H
W
--
G
------------------------
K
Q
Y
D
I
H
N
L
Y
G
Y
S
M
A
V
A
T
A
E
A
A
K
T
V
F
P
N
K
R
S
F
I
L
T
R
S
T
F
A
G
S
G
K
F
A
-
A
H
-
W
L
G
D
N
T
A
T
W
D
D
L
R
W
S
I
P
G
V
L
E
F
N
L
F
G
I
P
M
V
G
P
D
I
C
G
F
A
--
L
------
D
-----------------------
T
P
E
E
L
C
R
R
W
M
Q
L
G
A
F
Y
P
F
S
R
N
H
N
G
Q
G
Y
K
D
Q
D
P
A
S
F
G
AD
S
---
L
--
L
L
N
S
--
S
R
H
Y
L
N
I
R
Y
T
L
L
P
Y
L
Y
T
L
F
F
R
A
H
S
R
G
D
T
V
A
R
P
L
L
H
E
F
Y
E
D
N
S
T
W
D
V
H
Q
Q
F
L
W
G
P
G
L
L
I
T
P
V
L
D
E
G
A
E
K
V
M
A
Y
V
P
D
A
-
V
W
---
Y
D
Y
E
T
G
S
Q
-----
V
R
W
-
R
K
Q
K
V
-----
E
M
E
L
P
G
D
K
I
G
L
H
L
R
G
G
Y
I
F
P
---------------------
T
---
Q
Q
P
N
T
T
T
L
A
--
S
R
--
K
N
P
L
G
L
-
I
I
A
L
D
-
E
--
N
K
E
A
K
G
E
L
F
W
D
D
G
E
T
K
D
-
T
-
V
A
N
K
V
Y
-
L
L
C
E
F
S
V
T
Q
N
R
L
E
-
V
N
I
S
Q
-
S
T
Y
---
K
D
P
--
N
--
N
L
A
F
N
E
I
K
I
L
G
----
T
E
E
P
S
N
V
T
V
K
H
NGVPST
S
P
T
V
T
Y
D
SNLK
V
A
I
I
T
DIDLLLG
E
A
Y
T
V
E
W
A
H--
35
HHSearch
89.47
27%
-63
- C3 -
3L4Y
10
MGA_HUMAN
A:
[84-822]
---------------------------------------------------------------------------------
N
V
---
L
L
T
A
E
Y
Q
T
S
N
R
F
H
F
K
L
T
D
Q
T
N
N
R
F
-
E
V
P
H
-
E
H
V
Q
S
F
------------
S
G
N
A
A
A
S
L
T
Y
Q
V
E
I
S
R
Q
P
F
S
I
-
K
V
T
R
-
R
S
N
N
R
V
L
F
--
D
S
S
-
I
G
P
L
L
----------
F
A
D
Q
F
L
Q
L
S
T
R
L
P
-
S
--
T
N
V
Y
G
L
G
E
H
V
-
H
Q
Q
---
Y
RHD
M
N
W
--
K
---
T
W
P
I
F
---
N
R
D
T
T
P
N
---
G
N
G
T
N
L
Y
G
A
Q
T
F
F
L
----
C
--
L
E
--
D
AS
G
L
S
F
G
V
F
L
M
N
S
N
A
M
E
V
V
--
L
-
Q
P
A
--
P
-------------------------------------------------------------------------------------------------------------------------------------------------------
A
I
T
--
Y
R
T
I
-
G
G
I
L
D
F
Y
V
F
L
G
N
T
P
E
Q
V
V
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Y
L
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L
I
G
R
P
A
L
P
S
Y
W
A
L
G
F
H
L
S
R
Y
E
Y
G
T
L
D
N
M
R
E
V
V
E
R
N
R
A
A
Q
L
P
Y
D
V
Q
H
A
D
I
D
Y
-----
M
D
--
E
R
R
D
F
T
Y
D
S
V
D
F
K
--
G
F
P
E
F
V
N
E
L
H
N
N
G
Q
K
L
V
I
I
V
D
P
A
I
S
N
N
--
S
SSSK-
P
----
Y
G
P
Y
D
R
G
S
D
M
K
I
W
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---------------------
Q
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--------------------------
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--------------------------
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--------------------
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N
-------------------
P
--------------------------
P
FTPRILDGYLFC
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-----------------
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--
T
----------------------------------------------------