@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0253: (2016-03-13 )
MNELLKIFLSMALTSVILIPLVWILRRIFNRYLSKGKIYYSWLIVFFFLTIPFAYIFFSFTKDNAFMWRNKTEFDGVTSIVMDQSGIVLQHDFKTVFWMTVLDYIWVAWLVIFLLTFIYRIASYRNFKKYVFSGARRVDDLEQLDILAETIEELNIKRPVELMINPLISSPIFLGLKKNVIVIPDETFSNVELHYIFKHELVHCKRKDMYYVWMVQFFTCIYWFNPLMYLMNKRIQMDRELACDEAVLATLSKSKYIGYGDTLLSSLAKSGNYKESYVAVSLHENTKALKERLMFIANYKAQNKKHNILFSISMIVLCIVGVLFSAFQADVFTLEKKKGITIERRK
Atome Classification :
(20 SA)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------.........10...--.....20-........30........40........50........60.....-...70........80...-.....90........100.......110.......120-.......130.......140.......150-.......160....-.---..170.----.....-.180....---...190---.......200.......210.......220.......230.......240........250.......260.......270.----......280.......290.......300.......310..--.....320.------......-330.....-----..340....-----------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
N
E
L
L
K
I
F
L
S
M
A
L
T
--
S
V
I
L
I
P
L
-
V
W
I
L
R
R
I
F
N
R
Y
LSKGK
I
Y
Y
S
W
L
I
V
F
F
F
L
T
I
P
F
A
Y
I
F
F
S
FTKD
N
A
F
-
M
WRNKTEFDG
V
T
S
I
V
MDQ-S
G
I
V
L
Q
HD
F
K
T
V
F
W
M
T
V
L
D
Y
I
W
V
A
W
L
V
I
F
L
L
T
F
I
Y
R
I
A
-
S
Y
R
N
F
K
K
Y
V
F
SGARRVD
D
L
E
Q
L
D
I
L
A
E
T
I
E
-ELNIKR
P
V
E
L
M
I
N
P
-L---ISS
P
I
F
----LGLKK-
N
V
I
V
IPDE---TFSN
V
E
---
L
H
Y
I
F
K
H
E
L
V
H
CKRK
D
M
Y
Y
V
W
M
V
Q
F
F
T
C
I
Y
W
F
N
P
L
M
Y
L
M
N
K
R
I
QMDREL-A
C
D
E
A
V
L
A
T
L
SKSKYIGY
G
D
T
L
L
S
S
L
A
KSGNY----K
E
S
Y
V
A
V
S
LHE
N
T
K
A
L
K
E
R
L
M
F
I
ANYKAQNKKH
N
I
L
F
S
I
S
M
--
I
V
L
C
I
V
G
V
L
------
F
S
A
F
Q
A
-
D
V
F
T
L
EKK-----K
G
I
TIERRK-----------
35
Fugue
91.20
17%
-120
- C2 -
4BS9
1
?
A:
[3-781]
PTALQIKPHFHVEIIEP
K
Q
V
Y
L
L
G
EQ
G
N
H
A
L
T
G
Q
L
Y
C
Q
I
LPFLNGEYT
R
E
Q
I
V
E
K
L
DGQVP
E
E
Y
I
D
F
V
L
S
R
L
V
E
K
GYLTEVAPELS
L
E
V
A
A
F
W
S
E
L
GIAPSV
V
A
E
G
L
K
Q
P
V
T
V
T
T
A
G
KGIR
E
G
I
V
A
N
L
A
A
A
L
E
E
A
G
I
Q
V
S
D
PTAQ
L
Q
V
V
L
T
DDYLQ
P
E
L
A
A
I
N
K
E
A
L
E
R
Q
Q
P
W
L
L
V
KPVGS
I
L
W
L
G
PLFVPGETGC
W
H
C
L
A
Q
R
L
Q
G
N
R
E
V
E
A
S
V
L
Q
Q
K
R
A
L
QERP
T
A
R
A
T
L
P
S
T
L
Q
T
G
L
Q
W
A
A
T
E
I
A
K
W
M
V
K
R
H
L
N
A
I
APGTARFPTLAG
K
I
F
T
F
N
QTTL
E
L
K
A
H
P
L
S
R
R
PQCPTCGDRE
T
L
Q
R
R
G
F
E
P
L
K
L
E
S
R
P
KHPE
Q
T
V
Q
K
Y
QHLIGPITGVVTELVRSR
A
S
G
L
C
E
A
I
E
R
Y
S
G
IFQGD
E
P
R
K
R
A
T
LAELGDLAIH
P
E
Q
C
L
HFS
D
R
Q
Y
D
N
R
E
S
S
N
E
R
A
T
V
T
H
D
W
I
P
Q
R
F
D
A
S
--
K
A
H
D
W
T
P
-
V
W
S
L
T
E
Q
T
H
K
Y
L
P
T
A
L
C
Y
Y
R
Y
----------------
P
F
P
P
E
H
R
F
--------------
C
R
S
D
S
-
N
G
N
A
A
G
N
T
L
E
E
A
I
L
Q
G
F
M
E
L
V
E
R
D
S
V
C
L
W
W
Y
N
R
V
S
R
P
A
V
D
L
S
S
F
D
E
P
Y
F
L
Q
L
Q
Q
F
Y
Q
T
Q
N
R
D
L
W
V
L
D
L
T
A
D
L
G
I
------------------
P
A
F
----
V
G
V
S
N
-
R
--------------------------------
K
A
G
S
S
E
R
I
I
L
G
F
G
A
H
L
D
P
T
V
A
I
L
R
A
L
T
E
V
N
Q
I
G
L
E
L
D
A
T
D
W
L
V
N
A
T
L
A
A
S
P
Y
L
V
A
D
A
S
--
Q
P
L
K
T
A
K
D
Y
----
P
R
R
W
--------
S
D
D
I
Y
T
D
V
M
T
C
V
E
I
A
K
Q
A
G
L
E
T
L
V
L
D
Q
T
R
PD
I
G
L
N
V
V
K
V
I
V
P
G
M
R
F
W
S
R
F
G
S
G
R
L
Y
D
V
P
V
K
-----
L
G
W
R
E
Q
P
L
A
EAQMNPTPMPF
43
Fugue
73.23
15%
-103
- C1 -
1L9V
-
NSP2_ROTSR
A:
[1-313]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
E
-
L
A
C
F
C
Y
P
H
L
E
ND
S
Y
K
F
I
P
F
N
N
L
A
I
K
A
M
L
T
A
K
V
D
K
K
D
M
D
K
F
Y
D
S
I
I
Y
G
I
A
P
P
P
Q
F
K
K
R
Y
N
T
N
D
N
S
R
G
M
N
F
E
T
I
M
F
T
K
V
A
M
L
I
C
E
A
L
N
S
L
K
V
T
Q
A
N
V
S
N
V
L
S
R
V
V
S
-------
I
R
H
L
E
N
L
V
I
R
K
E
-
N
P
Q
-------------------
D
I
L
F
H
S
---
K
D
L
L
L
K
S
T
L
I
A
I
G
Q
-
S
---
K
E
I
E
T
T
----
I
T
A
E
G
-
G
E
I
V
F
Q
N
A
---
A
F
T
M
W
K
---
L
T
Y
L
E
-
H
Q
L
M
P
-
I
L
D
Q
N
F
I
E
Y
K
V
T
L
N
E
------------
D
K
P
I
S
D
V
H
V
K
-
E
L
V
A
E
L
R
W
Q
Y
N
K
F
A
V
I
T
H
G
K
G
H
Y
R
I
V
K
Y
S
S
V
A
----
N
H
A
D
R
V
Y
A
T
F
K
S
N
V
K
T
G
V
N
N
D
F
N
L
L
D
Q
R
I
I
W
Q
N
W
Y
A
F
T
S
S
M
--
K
Q
----
G
N
T
------
L
D
V
C
K
R
-
L
L
F
Q
K
M
K
P
EKNPF
K
G
L
S
T
D
R
K
M
D
E
V
S-------
1
PsiBlast_PDB
65.80
32%
-129
- C2 -
4JIU
1
?
A:
[4-72]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
L
L
E
H
A
K
D
-
I
L
G
Y
Q
R
P
V
K
V
R
I
R
P
-
L
---
K
M
S
I
A
R
----
V
S
F
K
Y
-
G
T
I
T
L
-
D
P
---
A
V
L
N
L
E
E
E
E
M
F
Y
I
L
I
H
E
L
A
H
L
K
A
E
T
S
Y
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
62.84
36%
-89
- C2 -
4JIX
9
Y123_METJA
A:
[14-83]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
V
N
E
I
L
I
-
S
L
N
I
N
E
S
I
N
I
E
I
K
P
-
M
KQK
I
A
S
F
S
F
KTK
T
L
R
L
N
K
-
Y
V
V
----
E
---
N
F
D
E
E
L
---
L
H
Y
I
I
L
H
E
L
I
H
F
K
I
K
S
I
N
H
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_CBE
61.19
37%
-88
- C2 -
4JIX
6
Y123_METJA
B:
[14-81]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
I
V
N
E
I
L
I
-
S
L
N
I
N
E
S
I
N
I
E
I
K
P
-
M
KQK
I
A
S
F
S
F
KTK
T
L
R
L
N
K
-
Y
V
V
----
E
---
N
F
D
E
E
L
---
L
H
Y
I
I
L
H
E
L
I
H
F
K
I
K
S
I
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
57.86
16%
-62
- C2 -
3CQB
3
HTPX_VIBPA
A:
[24-106]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
E
H
W
L
L
E
T
V
G
R
Q
A
Q
-
Q
A
G
I
G
M
-
P
T
V
A
I
Y
D
S
A
---
D
I
N
A
F
A
----
T
G
A
K
-D
S
L
V
A
V
S
T
G
L
L
H
N
M
T
R
D
E
---
A
E
A
V
L
A
H
E
V
S
H
I
A
N
G
D
M
V
T
M
T
L
M
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
48.87
31%
-1
- C2 -
1YFS
-
SYA_AQUAE
A:
[99-158]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
G
D
Y
F
K
K
E
A
I
E
Y
A
W
E
F
V
T
E
V
L
K
L
P
K
E
K
L
Y
V
S
V
Y
K
D
D
E
E
-
A
Y
R
I
W
N
E
H
I
G
I
P
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
47.05
31%
0
- C2 -
3HTZ
-
SYA_AQUAE
A:
[98-158]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
G
D
Y
F
K
K
E
A
I
E
Y
A
W
E
F
V
T
E
V
L
K
L
P
K
E
K
L
Y
V
S
V
Y
K
D
D
E
E
-
A
Y
R
I
W
N
E
H
I
G
I
P
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
46.81
31%
11
- C2 -
1YFT
-
SYA_AQUAE
A:
[99-158]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
G
D
Y
F
K
K
E
A
I
E
Y
A
W
E
F
V
T
E
V
L
K
L
P
K
E
K
L
Y
V
S
V
Y
K
D
D
E
E
-
A
Y
R
I
W
N
E
H
I
G
I
P
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
46.58
31%
3
- C2 -
1YFR
-
SYA_AQUAE
A:
[99-158]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
G
D
Y
F
K
K
E
A
I
E
Y
A
W
E
F
V
T
E
V
L
K
L
P
K
E
K
L
Y
V
S
V
Y
K
D
D
E
E
-
A
Y
R
I
W
N
E
H
I
G
I
P
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
46.14
31%
-2
- C2 -
1RIQ
-
SYA_AQUAE
A:
[98-157]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
G
D
Y
F
K
K
E
A
I
E
Y
A
W
E
F
V
T
E
V
L
K
L
P
K
E
K
L
Y
V
S
V
Y
K
D
D
E
E
-
A
Y
R
I
W
N
E
H
I
G
I
P
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
HHSearch
45.53
17%
-29
- C2 -
3DTE
-
IRRE_DEIDV
A:
[62-134]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
-
H
V
I
L
I
N
S
Q
----
V
R
P
E
R
---
Q
R
F
T
L
A
H
E
I
S
H
A
L
L
L
G
D
D
D
L
L
S
D
--------
L
H
D
--
E
Y
E
G
D
R
L
E
Q
V
I
E
T
-
L
C
N
V
G
A
A
A
L
L
M
---------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
44.52
31%
0
- C2 -
1YGB
-
SYA_AQUAE
A:
[99-158]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
G
D
Y
F
K
K
E
A
I
E
Y
A
W
E
F
V
T
E
V
L
K
L
P
K
E
K
L
Y
V
S
V
Y
K
D
D
E
E
-
A
Y
R
I
W
N
E
H
I
G
I
P
S
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
Fugue
36.18
23%
137
- C2 -
2CPG
1
COPG_STRAG
A:
[1-43]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
K
K
R
L
T
I
T
L
S
E
S
V
L
E
N
L
E
K
M
A
R
E
M
GLS
K
S
A
M
I
S
V
A
L
E
N
Y
K
K
G
Q
----------------------------------------------------------------------------------
40
Fugue
35.78
6%
34
- C2 -
2JVG
-
SBI_STAAM
A:
[195-266]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
M
V
S
I
E
K
A
I
V
R
H
D
E
R
V
-
K
S
A
N
D
A
I
S
K
L
N
E
K
D
S
I
E
N
R
R
L
A
Q
R
E
V
N
K
A
P
M
D
----
V
K
E
H
L
Q
K
Q
L
D
A
L
V
A
Q
K
D
A
E
K
K
V
A
---------------------------------------------------------------------------
34
Fugue
33.42
21%
297
- C2 -
1WNN
-
?
A:
[1-23]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
T
P
A
Q
R
Q
A
R
L
L
R
M
S
A
Y
A
A
K
R
Q
A
S
-----------------------------------------------------------------
39
Fugue
30.60
17%
275
* C2 *
3DVK
-
B:
[1-23]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
H
M
G
K
I
Y
A
A
M
M
I
M
D
Y
Y
K
Q
S
K
V
K
K
-----------------------------------------------------------------
38
Fugue
30.08
18%
201
- C2 -
1R48
-
PROP_ECOLI
A:
[1-33]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
C
G
G
D
N
I
E
Q
K
I
D
D
I
D
H
E
I
A
-
D
L
Q
A
K
R
T
R
L
V
Q
Q
H
P
-
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
Fugue
30.07
20%
246
- C2 -
1BB1
1
?
A:
[4-34]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
E
I
A
----
A
I
E
Y
E
Q
A
A
I
K
E
E
I
A
A
I
K
D
K
I
A
A
I
K
E
Y
I
A
A
I
--------------------------------------------------------------------
37
Fugue
28.74
20%
206
- C2 -
3TQ2
1
?
A:
[4-36]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
V
S
A
L
K
E
K
V
S
A
L
K
E
Q
F
L
M
L
M
F
K
V
S
A
L
K
E
K
V
S
A
L
K
E
-----------------------------------------------------------