@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0285: (2016-03-14 )
MKKLTKGLGILLASSLVLGLAACGGGSDDKALSTEKITIGTTAGPHQQIAEEVQKLAKKDGLEIKIKTFDDYNTPNTALNDGDLDANNYQTIPFLEQQKKDKGYKLDVAFKTVAFPMGIYSNDIKDLKNLKKGDKIAVPNDPSNEYRGLKLFEDAGVIKLKDGVEEKATKKDIAENPLDLEIVELEASQIPAQLDEVAAAAINTNFAMGAGLSINKDAIYHEPTKDNPYPNVFVVRSANKDDEVVKTLEKYYHSDEVKAFIEKEFNGSVVPAF
Atome Classification :
(20 SA)
.........10........20........30........40.....-...50......-.-.60........70........80........90........100-........110.......120.......130-.......140.......150.......160..---..-...170.......180.......190...--.--...200.......210.......220---..---.-..---.---.230.......240.......250.......260...-....270.--------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
K
K
L
T
K
G
L
G
I
L
L
A
S
S
L
V
L
G
L
AACGGGSDDKALST
E
K
I
T
I
GTTAG
P
H
-
Q
Q
I
A
E
E
V
Q
K
L
A
-
K
-KDG
L
E
I
K
I
K
T
FDDYNTPNTALNDGDLDANNYQTIP
F
L
E
Q
QKK-D-KG
Y
K
L
D
V
A
F
K
T
V
A
F
PM
G
I
YS
N
D
I
K
D
L
K
N
LKK-G
D
K
I
AVPNDPSNEYRG
L
K
L
FEDA
G
V
I
K
LKDGV---
E
E
-
K
A
T
KKDIAENPL
D
L
E
I
V
E
L
E
A
S
QI
P
A
Q
L
D
--
E
--
V
A
A
A
A
INTNFAMGAGLSINKDAIYHE---PT---K-DN---P---YP
N
V
F
V
V
RSANK
D
D
E
V
V
K
T
L
E
K
Y
Y
H
S
D
E
V
K
A
F
I
E
K
EF-NGSVVPAF--------------
1
PsiBlast_PDB
96.84
50%
-57
- C4 -
4QHQ
2
?
A:
[2-241]
------------------------------------
I
K
V
G
T
V
A
G
P
D
-
S
E
V
W
Q
V
V
Q
K
V
A
-
K
E
K
E
G
L
N
V
K
V
I
E
F
N
D
Y
V
Q
P
N
A
A
L
D
S
G
D
L
D
A
N
S
F
Q
H
Q
P
Y
L
D
S
Q
V
K
-
Q
-
R
G
Y
K
I
V
S
A
G
L
T
Y
I
S
P
I
G
V
Y
S
K
K
F
K
S
L
K
D
L
P
Q
-
G
A
K
L
A
V
P
N
D
P
S
N
E
N
R
A
L
L
L
L
Q
T
Q
G
V
I
K
L
K
A
G
A
GTG
G
N
-
N
A
T
V
L
D
I
A
E
N
P
K
K
L
K
I
S
E
L
D
A
A
Q
L
P
R
V
L
S
--
D
--
V
D
A
A
V
I
N
T
N
Y
A
L
A
A
N
L
Q
P
T
K
D
A
I
A
L
E
----
S
---
L
-
T
S
---
P
---
Y
A
N
L
I
A
V
R
A
K
D
K
D
Q
P
W
V
K
K
L
V
K
A
Y
Q
S
P
E
V
K
E
F
I
K
K
Q
F
-
K
G
S
M
V
A
S
F
--------------
3
PsiBlast_PDB
96.38
46%
-58
- C4 -
3TQW
1
?
A:
[4-240]
-----------------------------------
M
V
R
V
G
T
I
A
G
P
E
-
T
Q
L
M
E
V
A
K
Q
V
A
L
N
-
R
Y
G
L
H
V
N
I
I
T
F
S
D
Y
N
T
P
N
E
A
L
A
D
G
S
V
D
A
N
M
F
Q
H
L
P
Y
L
K
A
Q
I
E
-
M
-
R
G
Y
K
I
V
S
I
G
K
T
F
V
Y
P
M
G
L
Y
S
K
K
I
T
A
L
T
Q
L
K
T
-
G
A
K
I
A
V
P
S
D
P
S
N
E
A
R
A
L
L
L
L
E
K
A
Q
L
I
Q
L
K
T
H
-----
I
-
N
A
T
P
M
D
I
A
S
N
P
K
K
L
K
I
V
E
L
D
A
A
Q
L
S
R
S
L
G
--
D
--
V
D
L
A
A
I
N
T
N
Y
A
I
P
A
G
L
S
P
S
R
D
A
L
L
T
E
----
G
---
P
-
N
S
---
P
---
Y
A
N
V
V
A
V
R
E
D
D
K
N
D
P
R
L
K
Q
L
V
S
A
L
H
S
P
A
V
L
S
A
A
K
K
I
F
-
G
D
G
A
I
P
A
---------------
35
HHSearch
96.27
47%
-58
- C4 -
3TQW
1
?
A:
[4-240]
-----------------------------------
M
V
R
V
G
T
I
A
G
P
E
-
T
Q
L
M
E
V
A
K
Q
V
A
L
N
-
R
Y
G
L
H
V
N
I
I
T
F
S
D
Y
N
T
P
N
E
A
L
A
D
G
S
V
D
A
N
M
F
Q
H
L
P
Y
L
K
A
Q
I
E
-
M
-
R
G
Y
K
I
V
S
I
G
K
T
F
V
Y
P
M
G
L
Y
S
K
K
I
T
A
L
T
Q
L
K
T
-
G
A
K
I
A
V
P
S
D
P
S
N
E
A
R
A
L
L
L
L
E
K
A
Q
L
I
Q
L
K
T
H
-----
I
-
N
A
T
P
M
D
I
A
S
N
P
K
K
L
K
I
V
E
L
D
A
A
Q
L
S
R
S
L
G
--
D
--
V
D
L
A
A
I
N
T
N
Y
A
I
P
A
G
L
S
P
S
R
D
A
L
L
T
E
---
G
----
P
-
N
S
---
P
---
Y
A
N
V
V
A
V
R
E
D
D
K
N
D
P
R
L
K
Q
L
V
S
A
L
H
S
P
A
V
L
S
A
A
K
K
I
F
-
G
D
G
A
I
P
A
---------------
2
PsiBlast_PDB
93.03
46%
-48
- C4 -
4YAH
1
METQ_ECOLI
X:
[29-271]
--------------------------------
D
P
N
H
I
K
V
G
V
I
V
G
A
E
-
Q
Q
V
A
E
V
A
Q
K
V
A
-
K
D
K
Y
G
L
D
V
E
L
V
T
F
N
D
Y
V
L
P
N
E
A
L
S
K
G
D
I
D
A
N
A
F
Q
H
K
P
Y
L
D
Q
Q
L
K
-
D
-
R
G
Y
K
L
V
A
V
G
N
T
F
V
Y
P
I
A
G
Y
S
K
K
I
K
S
L
D
E
L
Q
D
-
G
S
Q
V
A
V
P
N
D
P
T
N
L
G
R
S
L
L
L
L
Q
K
V
G
L
I
K
L
K
D
G
V
---
G
L
-
L
P
T
V
L
D
V
V
E
N
P
K
N
L
K
I
V
E
L
E
A
P
Q
L
P
R
S
L
D
DA
Q
--
I
A
L
A
V
I
N
T
T
Y
A
S
Q
I
G
L
T
P
A
K
D
G
I
F
V
E
----
D
---
K
-
E
S
---
P
---
Y
V
N
L
I
V
T
R
E
D
N
K
D
A
E
N
V
K
K
F
V
Q
A
Y
Q
S
D
E
V
Y
E
A
A
N
K
V
F
-
N
G
G
A
V
K
G
W
--------------
5
PsiBlast_PDB
91.11
42%
0
- C- -
4K3F
-
?
A:
[3--1]
----------------------------------
E
S
L
T
V
A
A
T
P
V
P
H
-
A
E
I
L
N
V
V
K
P
L
L
-
A
-
K
E
G
V
D
L
K
I
K
E
F
T
D
Y
V
Q
P
N
V
Q
V
S
E
K
R
L
D
A
N
F
F
Q
H
Q
P
Y
L
D
E
F
N
K
-
A
-
K
G
T
D
L
V
A
V
T
G
V
H
I
E
P
L
G
A
Y
S
S
K
Y
K
K
L
D
E
L
P
S
-
G
A
T
V
V
I
P
N
D
A
T
N
G
G
R
A
L
L
L
L
D
K
A
G
V
I
K
L
K
D
N
K
---
S
I
-
T
A
T
P
K
D
I
V
D
N
P
K
N
I
K
I
R
E
L
E
A
A
T
L
P
R
V
L
T
--
Q
--
V
D
M
A
L
I
N
T
N
Y
A
L
E
A
K
L
N
P
T
K
D
A
L
A
I
E
---
G
S
-----
D
S
---
P
---
Y
V
N
I
L
V
A
R
P
D
N
K
D
S
D
A
M
Q
K
L
A
K
A
L
H
S
A
E
I
K
Q
F
I
Q
E
K
Y
-
K
G
A
V
V
P
A
F
--------------
4
PsiBlast_PDB
90.08
40%
-53
- C4 -
4IB2
7
?
A:
[6-250]
-------------------------
S
S
E
D
----
A
K
T
I
K
V
A
A
S
A
T
P
H
-
A
E
I
L
E
Q
A
K
S
I
L
-
K
-
K
E
G
Y
Q
L
E
V
T
V
F
D
D
Y
V
Q
P
N
E
V
V
E
S
G
E
F
D
A
N
Y
F
Q
H
V
P
Y
L
E
S
F
N
E
-
E
-
K
G
T
H
L
V
D
A
G
D
I
H
Y
E
P
F
G
I
Y
P
G
T
K
K
S
L
D
E
I
S
E
-
G
D
K
I
A
V
P
N
D
T
T
N
E
A
R
A
L
L
L
L
Q
D
N
G
I
I
T
L
K
D
G
A
---
G
L
-
N
A
T
V
N
D
I
E
E
N
P
Y
N
V
E
I
V
E
L
E
A
A
Q
V
A
R
V
T
G
--
E
--
T
A
Y
V
V
L
N
G
N
Y
A
L
E
A
G
Y
S
V
A
K
D
A
L
A
Y
E
---
K
S
---
D
-
S
E
---
A
A
K
T
Y
V
N
I
I
A
V
K
E
G
N
E
K
E
E
K
I
Q
A
L
V
K
A
L
K
S
D
E
I
K
E
Y
I
E
K
T
Y
-
D
G
A
V
I
P
----------------
21
PsiBlast_CBE
89.96
40%
-54
- C4 -
4IB2
8
?
B:
[10-250]
---------------------------------
A
K
T
I
K
V
A
A
S
A
T
P
H
-
A
E
I
L
E
Q
A
K
S
I
L
-
K
-
K
E
G
Y
Q
L
E
V
T
V
F
D
D
Y
V
Q
P
N
E
V
V
E
S
G
E
F
D
A
N
Y
F
Q
H
V
P
Y
L
E
S
F
N
E
-
E
-
K
G
T
H
L
V
D
A
G
D
I
H
Y
E
P
F
G
I
Y
P
G
T
K
K
S
L
D
E
I
S
E
-
G
D
K
I
A
V
P
N
D
T
T
N
E
A
R
A
L
L
L
L
Q
D
N
G
I
I
T
L
K
D
G
A
---
G
L
-
N
A
T
V
N
D
I
E
E
N
P
Y
N
V
E
I
V
E
L
E
A
A
Q
V
A
R
V
T
G
--
E
--
T
A
Y
V
V
L
N
G
N
Y
A
L
E
A
G
Y
S
V
A
K
D
A
L
A
Y
E
---
K
S
---
D
-
S
E
---
A
A
K
T
Y
V
N
I
I
A
V
K
E
G
N
E
K
E
E
K
I
Q
A
L
V
K
A
L
K
S
D
E
I
K
E
Y
I
E
K
T
Y
-
D
G
A
V
I
P
----------------
34
HHSearch
89.90
31%
-58
- C4 -
1XS5
1
TPN32_TREPA
A:
[2-237]
---------------------------------
D
E
T
V
G
V
G
V
L
S
E
P
H
-
A
R
L
L
E
I
A
K
E
E
V
-
K
-
K
Q
H
I
E
L
R
I
V
E
F
T
N
Y
V
A
L
N
E
A
V
M
R
G
D
I
L
M
N
F
F
Q
H
V
P
H
M
Q
Q
F
N
Q
-
E
-
H
N
G
D
L
V
S
V
G
N
V
H
V
E
P
L
A
L
Y
S
R
T
Y
R
H
V
S
D
F
P
A
-
G
A
V
I
A
I
P
N
D
S
S
N
E
A
R
A
L
R
L
L
E
A
A
G
F
I
R
M
R
A
G
S
---
G
L
-
F
A
T
V
E
D
V
Q
Q
N
V
R
N
V
V
L
Q
E
V
E
S
A
L
L
P
R
V
F
D
--
Q
--
V
D
G
A
V
I
N
G
N
Y
A
I
M
A
G
L
S
A
R
R
D
G
L
A
V
E
---
P
----
D
-
A
S
---
A
---
Y
A
N
V
L
V
V
K
R
G
N
E
A
D
A
R
V
Q
A
V
L
R
A
L
C
G
G
R
V
R
T
Y
L
K
E
R
Y
-
K
G
G
E
V
-----------------
15
PsiBlast_PDB
89.32
30%
-56
- C4 -
1XS5
1
TPN32_TREPA
A:
[3-240]
----------------------------------
E
T
V
G
V
G
V
L
S
E
P
H
-
A
R
L
L
E
I
A
K
E
E
V
-
K
-
K
Q
H
I
E
L
R
I
V
E
F
T
N
Y
V
A
L
N
E
A
V
M
R
G
D
I
L
M
N
F
F
Q
H
V
P
H
M
Q
Q
F
N
Q
-
E
-
H
N
G
D
L
V
S
V
G
N
V
H
V
E
P
L
A
L
Y
S
R
T
Y
R
H
V
S
D
F
P
A
-
G
A
V
I
A
I
P
N
D
S
S
N
E
A
R
A
L
R
L
L
E
A
A
G
F
I
R
M
R
A
G
S
---
G
L
-
F
A
T
V
E
D
V
Q
Q
N
V
R
N
V
V
L
Q
E
V
E
S
A
L
L
P
R
V
F
D
--
Q
--
V
D
G
A
V
I
N
G
N
Y
A
I
M
A
G
L
S
A
R
R
D
G
L
A
V
E
---
P
D
---
A
--
S
---
A
---
Y
A
N
V
L
V
V
K
R
G
N
E
A
D
A
R
V
Q
A
V
L
R
A
L
C
G
G
R
V
R
T
Y
L
K
E
R
Y
K
G
G
E
V
A
P
A
---------------
53
Fugue
87.85
40%
-55
* C4 *
1P99
2
?
A:
[40-294]
-----------------------------------
K
V
T
I
G
V
A
-
S
N
D
-
T
K
A
W
E
K
V
K
E
L
A
-
K
-
K
D
D
I
D
V
E
I
K
H
F
S
D
Y
N
L
P
N
K
A
L
N
D
G
D
I
D
M
N
A
F
Q
H
F
A
F
L
D
Q
Y
K
K
-
A
H
K
G
T
K
I
S
A
L
S
T
T
V
L
A
P
L
G
I
Y
S
D
K
I
K
D
V
K
K
V
K
D
-
G
A
K
V
V
I
P
N
D
V
S
N
Q
A
R
A
L
K
L
L
E
A
A
G
L
I
K
L
K
K
D
F
---
G
L
-
A
G
T
V
K
D
I
T
S
N
P
K
H
L
K
I
T
A
V
D
A
Q
Q
T
A
R
A
L
S
--
D
--
V
D
I
A
V
I
N
N
G
V
A
T
K
A
G
K
D
P
K
N
D
P
I
F
L
E
KSN
S
D
---
A
-
V
K
---
P
---
Y
I
N
I
V
A
V
N
D
K
D
L
D
N
K
T
Y
A
K
I
V
E
L
Y
H
S
K
E
A
Q
K
A
L
Q
E
D
V
-
K
D
G
E
K
P
V
N
L
S
K
D
E
I
K
A
I
E
T
S
L
A
7
PsiBlast_PDB
87.42
43%
-57
- C4 -
3K2D
1
?
A:
[3-228]
-------------------------------
M
D
T
S
K
V
K
V
G
V
M
A
G
A
E
-
A
Q
V
A
E
V
A
A
K
V
A
-
K
E
K
Y
G
L
D
V
E
L
V
T
F
T
D
Y
V
T
P
N
A
A
L
D
D
G
S
I
D
M
N
A
F
Q
H
K
P
Y
L
D
R
Q
V
E
-
D
-
R
D
Y
K
L
T
I
A
G
N
T
F
V
Y
P
I
A
G
Y
S
K
Q
V
K
S
V
A
A
L
A
D
-
G
V
R
I
A
V
P
N
D
P
T
N
L
G
R
S
L
L
L
L
E
Q
Q
G
L
I
K
L
R
P
E
V
---
G
L
-
L
A
T
V
R
D
I
V
E
N
P
K
N
I
T
I
M
E
L
D
A
A
Q
L
P
R
S
L
D
--
D
--
V
A
L
S
I
I
N
T
T
Y
A
S
S
I
N
L
T
P
E
K
D
G
V
F
V
E
----
D
---
K
-
E
S
---
P
---
Y
V
N
L
I
V
A
R
Q
D
N
V
Q
N
E
N
V
Q
N
F
V
K
A
Y
Q
T
E
E
V
-------------------------------
6
PsiBlast_PDB
87.24
39%
0
- C- -
4OTE
-
?
A:
[4--1]
----------------------------
D
K
-----
K
I
V
V
G
A
T
L
V
P
G
-
G
E
L
L
E
E
L
K
P
L
I
-
K
-
E
K
G
Y
T
L
E
V
K
N
F
D
D
Y
I
L
P
N
E
A
L
N
N
G
E
I
D
A
N
L
F
Q
H
E
P
Y
L
K
E
A
V
K
-
A
-
K
G
Y
K
I
M
A
G
K
K
L
Y
V
C
P
A
I
L
Y
S
Y
K
I
K
S
V
D
E
F
K
K
-
G
D
T
I
A
I
S
N
N
P
S
S
C
S
K
N
L
R
Y
L
E
S
I
G
L
L
T
L
P
K
G
----
D
G
-
L
V
S
P
K
D
I
I
E
N
P
K
G
I
Q
F
K
E
L
D
I
A
Q
I
P
S
S
L
P
--
D
--
V
T
A
A
F
I
D
T
T
Y
A
V
P
A
G
L
D
A
K
K
N
G
I
Y
T
A
---
P
I
---
N
-
D
E
-------
Y
A
N
L
L
A
F
R
T
E
D
K
D
S
E
K
I
K
V
L
Q
D
V
L
T
S
D
K
A
R
S
L
I
E
E
K
Y
-
K
G
I
V
I
P
T
F
--------------
22
PsiBlast_CBE
85.90
43%
-58
- C4 -
3K2D
1
?
B:
[8-228]
------------------------------------
V
K
V
G
V
M
A
G
A
E
-
A
Q
V
A
E
V
A
A
K
V
A
-
K
E
K
Y
G
L
D
V
E
L
V
T
F
T
D
Y
V
T
P
N
A
A
L
D
D
G
S
I
D
M
N
A
F
Q
H
K
P
Y
L
D
R
Q
V
E
-
D
-
R
D
Y
K
L
T
I
A
G
N
T
F
V
Y
P
I
A
G
Y
S
K
Q
V
K
S
V
A
A
L
A
D
-
G
V
R
I
A
V
P
N
D
P
T
N
L
G
R
S
L
L
L
L
E
Q
Q
G
L
I
K
L
R
P
E
V
---
G
L
-
L
A
T
V
R
D
I
V
E
N
P
K
N
I
T
I
M
E
L
D
A
A
Q
L
P
R
S
L
D
--
D
--
V
A
L
S
I
I
N
T
T
Y
A
S
S
I
N
L
T
P
E
K
D
G
V
F
V
E
----
D
---
K
-
E
S
---
P
---
Y
V
N
L
I
V
A
R
Q
D
N
V
Q
N
E
N
V
Q
N
F
V
K
A
Y
Q
T
E
E
V
-------------------------------
17
PsiBlast_PDB
85.13
32%
-56
- C4 -
4NTL
11
?
A:
[8-247]
-----------------------------------
E
I
T
V
A
V
Q
L
E
S
S
-
K
D
I
L
E
I
A
K
K
E
A
-
E
-
K
K
G
Y
K
I
N
I
M
E
V
S
D
N
V
A
Y
N
D
A
V
Q
H
D
E
A
D
A
N
F
A
Q
H
Q
P
F
M
E
M
F
N
K
-
E
-
K
K
A
D
L
V
A
V
Q
P
I
Y
Y
F
A
G
G
F
Y
S
K
E
Y
Q
D
A
K
D
L
P
E
-
N
A
K
V
G
I
P
S
D
P
T
N
E
G
R
A
L
A
I
L
N
A
N
G
V
I
K
L
K
E
G
V
---
G
F
-
N
G
T
V
A
D
V
V
E
N
P
K
N
I
T
F
E
S
I
D
L
L
N
L
A
K
A
Y
D
--
E
KD
I
A
M
V
F
C
Y
P
A
Y
L
E
P
A
G
L
T
-
T
K
D
A
I
L
L
E
---
D
K
---
E
A
S
K
---
H
---
Y
A
L
Q
V
V
T
R
K
G
E
K
D
S
E
K
I
K
V
L
K
E
A
M
T
T
K
E
V
A
E
Y
I
K
K
N
S
-
K
G
A
N
I
P
A
F
--------------
12
PsiBlast_PDB
85.03
40%
-59
- C4 -
1P99
2
?
A:
[40-271]
-----------------------------------
K
V
T
I
G
V
-
A
S
N
D
-
T
K
A
W
E
K
V
K
E
L
A
-
K
-
K
D
D
I
D
V
E
I
K
H
F
S
D
Y
N
L
P
N
K
A
L
N
D
G
D
I
D
M
N
A
F
Q
H
F
A
F
L
D
Q
Y
K
K
A
H
-
K
G
T
K
I
S
A
L
S
T
T
V
L
A
P
L
G
I
Y
S
D
K
I
K
D
V
K
K
V
K
D
-
G
A
K
V
V
I
P
N
D
V
S
N
Q
A
R
A
L
K
L
L
E
A
A
G
L
I
K
L
K
K
D
F
---
G
L
-
A
G
T
V
K
D
I
T
S
N
P
K
H
L
K
I
T
A
V
D
A
Q
Q
T
A
R
A
L
S
--
D
--
V
D
I
A
V
I
N
N
G
V
A
T
K
A
G
K
D
P
K
N
D
P
I
F
L
E
---
K
S
---
N
-
S
D
AVK
P
---
Y
I
N
I
V
A
V
N
D
K
D
L
D
N
K
T
Y
A
K
I
V
E
L
Y
H
S
K
E
A
Q
K
A
L
Q
E
D
------------------------
29
PsiBlast_CBE
84.51
37%
-48
- C4 -
3IR1
5
?
E:
[1-237]
----------------------------------
K
E
I
V
F
G
T
T
V
G
D
F
G
D
M
V
K
E
Q
I
Q
P
E
L
-
E
-
K
K
G
Y
T
V
K
L
V
E
F
T
D
Y
V
R
P
N
L
A
L
A
E
G
E
L
D
I
N
V
F
Q
H
K
P
Y
L
D
D
F
K
K
-
E
-
H
N
L
D
I
T
E
V
F
Q
V
P
T
A
P
L
G
L
Y
P
G
K
L
K
S
L
E
E
V
K
D
-
G
S
T
V
S
A
P
N
D
P
S
N
F
A
R
V
L
V
M
L
D
E
L
G
W
I
K
L
K
D
G
I
---
N
P
L
T
A
S
K
A
D
I
A
E
N
L
K
N
I
K
I
V
E
L
E
A
A
Q
L
P
R
S
R
A
--
D
--
V
D
F
A
V
V
N
G
N
Y
A
I
S
S
G
M
K
L
T
-
E
A
L
F
Q
E
---
P
S
------
F
---
A
---
Y
V
N
W
S
A
V
K
T
A
D
K
D
S
Q
W
L
K
D
V
T
E
A
Y
N
S
D
A
F
K
A
Y
A
H
K
R
F
-
E
G
Y
K
S
P
A
---------------
31
PsiBlast_CBE
84.40
37%
-48
- C4 -
3IR1
7
?
C:
[1-237]
----------------------------------
K
E
I
V
F
G
T
T
V
G
D
F
G
D
M
V
K
E
Q
I
Q
P
E
L
-
E
-
K
K
G
Y
T
V
K
L
V
E
F
T
D
Y
V
R
P
N
L
A
L
A
E
G
E
L
D
I
N
V
F
Q
H
K
P
Y
L
D
D
F
K
K
-
E
-
H
N
L
D
I
T
E
V
F
Q
V
P
T
A
P
L
G
L
Y
P
G
K
L
K
S
L
E
E
V
K
D
-
G
S
T
V
S
A
P
N
D
P
S
N
F
A
R
V
L
V
M
L
D
E
L
G
W
I
K
L
K
D
G
I
---
N
P
L
T
A
S
K
A
D
I
A
E
N
L
K
N
I
K
I
V
E
L
E
A
A
Q
L
P
R
S
R
A
--
D
--
V
D
F
A
V
V
N
G
N
Y
A
I
S
S
G
M
K
L
T
-
E
A
L
F
Q
E
---
P
S
------
F
---
A
---
Y
V
N
W
S
A
V
K
T
A
D
K
D
S
Q
W
L
K
D
V
T
E
A
Y
N
S
D
A
F
K
A
Y
A
H
K
R
F
-
E
G
Y
K
S
P
A
---------------
33
HHSearch
84.34
39%
-57
- C4 -
1P99
2
?
A:
[40-274]
-----------------------------------
K
V
T
I
G
V
A
S
N
D
T
--
K
A
W
E
K
V
K
E
L
A
-
K
-
K
D
D
I
D
V
E
I
K
H
F
S
D
Y
N
L
P
N
K
A
L
N
D
G
D
I
D
M
N
A
F
Q
H
F
A
F
L
D
Q
Y
K
K
-
A
H
K
G
T
K
I
S
A
L
S
T
T
V
L
A
P
L
G
I
Y
S
D
K
I
K
D
V
K
K
V
-
K
D
G
A
K
V
V
I
P
N
D
V
S
N
Q
A
R
A
L
K
L
L
E
A
A
G
L
I
K
L
K
K
D
F
---
G
L
-
A
G
T
V
K
D
I
T
S
N
P
K
H
L
K
I
T
A
V
D
A
Q
Q
T
A
R
A
L
S
--
D
--
V
D
I
A
V
I
N
N
G
V
A
T
K
A
G
K
D
P
K
N
D
P
I
F
L
E
---
K
S
NSD
A
-
V
K
---
P
---
Y
I
N
I
V
A
V
N
D
K
D
L
D
N
K
T
Y
A
K
I
V
E
L
Y
H
S
K
E
A
Q
K
A
L
Q
E
D
V
-
K
D
--------------------
8
PsiBlast_PDB
84.28
37%
-46
- C4 -
3GXA
7
?
A:
[23-259]
----------------------------------
K
E
I
V
F
G
T
T
V
G
D
F
G
D
M
V
K
E
Q
I
Q
P
E
L
-
E
-
K
K
G
Y
T
V
K
L
V
E
F
T
D
Y
V
R
P
N
L
A
L
A
E
G
E
L
D
I
N
V
F
Q
H
K
P
Y
L
D
D
F
K
K
-
E
-
H
N
L
D
I
T
E
V
F
Q
V
P
T
A
P
L
G
L
Y
P
G
K
L
K
S
L
E
E
V
K
D
-
G
S
T
V
S
A
P
N
D
P
S
N
F
A
R
V
L
V
M
L
D
E
L
G
W
I
K
L
K
D
G
I
---
N
P
L
T
A
S
K
A
D
I
A
E
N
L
K
N
I
K
I
V
E
L
E
A
A
Q
L
P
R
S
R
A
--
D
--
V
D
F
A
V
V
N
G
N
Y
A
I
S
S
G
M
K
L
T
-
E
A
L
F
Q
E
---
P
S
------
F
---
A
---
Y
V
N
W
S
A
V
K
T
A
D
K
D
S
Q
W
L
K
D
V
T
E
A
Y
N
S
D
A
F
K
A
Y
A
H
K
R
F
-
E
G
Y
K
S
P
A
---------------
23
PsiBlast_CBE
84.26
37%
-47
- C4 -
3GXA
7
?
F:
[23-259]
----------------------------------
K
E
I
V
F
G
T
T
V
G
D
F
G
D
M
V
K
E
Q
I
Q
P
E
L
-
E
-
K
K
G
Y
T
V
K
L
V
E
F
T
D
Y
V
R
P
N
L
A
L
A
E
G
E
L
D
I
N
V
F
Q
H
K
P
Y
L
D
D
F
K
K
-
E
-
H
N
L
D
I
T
E
V
F
Q
V
P
T
A
P
L
G
L
Y
P
G
K
L
K
S
L
E
E
V
K
D
-
G
S
T
V
S
A
P
N
D
P
S
N
F
A
R
V
L
V
M
L
D
E
L
G
W
I
K
L
K
D
G
I
---
N
P
L
T
A
S
K
A
D
I
A
E
N
L
K
N
I
K
I
V
E
L
E
A
A
Q
L
P
R
S
R
A
--
D
--
V
D
F
A
V
V
N
G
N
Y
A
I
S
S
G
M
K
L
T
-
E
A
L
F
Q
E
---
P
S
------
F
---
A
---
Y
V
N
W
S
A
V
K
T
A
D
K
D
S
Q
W
L
K
D
V
T
E
A
Y
N
S
D
A
F
K
A
Y
A
H
K
R
F
-
E
G
Y
K
S
P
A
---------------