@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0298: (2016-03-14 )
MRFNTISEKMDQYISPLANKLSQQRHLKATRDAFMSMLPITLFGSIPIILKAAPVTDDTKNGFLLAWANFAEKYDLILNWISGITLGAMSLYICVGITYYLCKHYHEDFLRPLMFSIAGFFMLVLNPIKMGWDGKEVDISFLDGRGILLSIFVAIVTVEGYHWMRKKNVGRITMPDSVPASLSETFAALVPGIILMTFFSIIFIIFNLLDTTAIQFLYEKMAPSFKAADSLPFTILSIFLVHLFWFFGVHDAALAGILGPIRDGNLSINAAEKMAGQDLTNIFTTPFWTYFVIIGGSGSVLALAFLMMRSKSKQLSTVGKVGFLPSIFGISEPLIFGTPLMLNPIFFFPFIFTSVFNGVITYLCMYFGIVGKTFAVFSWQMPAPIGAFLSTMDWRAIVLVFILIFLNGLMYYPFLKVYEKNLVALEKEAEEENIAAN
Atome Classification :
(20 SA)
.........10........20.-.......30........40........50........60........70........80........90........100.......110.......120.....-..130.------....-------...140------.........150.......160.......170.......180.......190.......200......-.210.......220--........230.......240.......250..-..-...260.......270.......280.......290.......300...-..-..-310.......320.......330.......340---.........350----........360.......370-..--..-...380.......-390.-.......400.......410.......420.......430.....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MRF
N
T
I
S
E
K
M
D
Q
Y
I
S
P
L
A
N
K
L
S
-
Q
Q
R
H
L
K
A
T
R
D
A
F
M
S
M
L
P
I
T
LFGSI
P
I
I
L
K
AAPVTDDTKN
G
F
L
L
A
W
A
N
F
A
E
K
Y
D
L
I
L
N
W
I
S
G
I
T
L
G
A
M
S
L
Y
I
C
V
G
I
T
Y
Y
L
C
K
H
Y
H
E
D
F
L
R
P
L
M
F
S
I
A
G
F
F
M
L
V
L
N
P
-
I
KMG-W------DG
K
E
-------
V
D
I
S
--------
F
LDGR
G
I
L
L
S
I
F
V
A
I
V
TVEG
Y
H
W
M
R
KKNVGRITMPDSV
P
A
S
L
S
E
T
F
A
A
L
V
P
G
I
I
L
M
T
F
F
S
I
I
F
I
I
F
N
L
-
L
D
T
T
A
I
Q
F
L
Y
E
K
-M--APSFKAADSL
P
F
T
I
L
S
I
F
L
V
H
L
F
W
F
FGV
H
D
A
A
L
-
A
G
-
I
LGPIRDG
N
L
S
I
N
A
A
E
K
MAG
Q
D
L
T
N
I
FTTP
F
W
T
Y
F
V
I
IGGS
G
S
V
L
A
L
A
F
-
L
M
-
M
R
-SKS
K
Q
L
S
TVGKVGF
L
P
S
I
FGISEPLIFGTPL-----ML
N
P
I
F
F
F
P
F
I
-----
F
T
S
V
F
N
G
V
I
T
Y
L
C
M
Y
F
G
I
VGK-
T
F
--
A
V
-
F
S
WQMPA
P
I
G
A
F
L
-
S
T-M-
D
W
R
A
I
V
L
V
F
I
L
I
F
L
N
G
L
M
Y
Y
P
F
L
K
V
Y
E
K
N
L
V
A
L
E
K
EAEEENIAAN
16
Fugue
97.61
29%
-135
- C4 -
3QNQ
8
?
A:
[3-434]
-------
R
F
L
E
K
Y
V
M
P
V
A
G
K
V
A
-
E
Q
R
H
L
L
A
I
R
D
G
L
V
L
T
M
P
F
L
I
I
G
S
I
F
L
I
I
S
T
L
P
I
----
P
G
Y
S
E
F
M
A
S
L
F
G
K
N
W
N
V
A
L
G
Y
P
V
S
A
T
F
N
I
M
A
L
I
A
V
F
G
I
A
Y
R
L
G
E
Y
Y
K
V
D
A
L
A
S
G
A
L
S
L
V
T
F
L
L
A
T
P
F
Q
-
V
A
Y
I
-
M
------
P
G
T
K
-------
E
S
I
L
V
D
GVIP
A
A
L
M
G
S
Q
G
L
F
V
A
M
I
I
A
I
I
S
T
E
I
Y
R
F
L
V
Q
K
K
M
-
I
I
K
M
P
E
T
V
P
P
A
V
T
R
S
F
A
A
L
I
P
G
F
I
V
V
T
V
V
W
I
I
R
L
I
F
E
H
-
T
T
F
G
S
I
H
N
V
V
G
K
-
L
L
Q
E
P
L
S
I
L
G
A
S
L
W
G
A
V
I
A
V
I
L
V
H
V
L
W
A
C
G
I
H
G
A
T
I
-
V
G
G
V
M
S
P
I
W
L
S
L
M
D
Q
N
R
I
A
F
Q
A
G
Q
D
V
P
N
T
I
T
A
Q
F
F
D
L
W
I
Y
M
G
G
S
G
A
T
L
A
L
V
V
-
G
M
-
L
L
F
A
R
S
Q
Q
L
K
S
L
G
R
L
S
I
A
P
G
I
F
N
I
N
E
M
V
T
F
G
M
P
I
-----
V
M
N
P
L
L
L
I
P
F
I
-----
V
V
P
V
V
L
T
I
V
S
Y
F
A
M
E
W
G
L
V
A
R
-
P
S
--
G
A
A
V
T
W
T
T
P
I
L
F
S
G
Y
L
-
G
S
G
G
-
K
I
S
G
V
I
L
Q
L
V
N
F
A
L
A
F
V
I
Y
L
P
F
L
K
I
W
D
K
Q
K
I
A
E
E
K
G
E
A
-------
7
HHSearch
97.20
29%
-131
- C4 -
3QNQ
8
?
A:
[3-434]
-------
R
F
L
E
K
Y
V
M
P
V
A
G
K
V
A
-
E
Q
R
H
L
L
A
I
R
D
G
L
V
L
T
M
P
F
L
I
I
G
S
I
F
L
I
I
S
T
L
P
I
-
P
-
G
Y
S
E
F
M
A
S
L
F
G
--
K
N
W
N
V
A
L
G
Y
P
V
S
A
T
F
N
I
M
A
L
I
A
V
F
G
I
A
Y
R
L
G
E
Y
Y
K
V
D
A
L
A
S
G
A
L
S
L
V
T
F
L
L
A
T
P
F
Q
V
A
Y
I
M
P
G
TK
E
S
I
L
V
D
G
V
-------
I
P
A
A
--------
L
M
G
S
Q
G
L
F
V
A
M
I
I
A
I
I
S
T
E
I
Y
R
F
L
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Q
K
-
K
M
I
I
K
M
P
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T
V
P
P
A
V
T
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S
F
A
A
L
I
P
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F
I
V
V
T
V
V
W
I
I
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L
I
F
E
H
T
T
F
G
S
I
H
N
V
V
G
K
L
L
Q
--
E
P
L
S
I
L
G
A
S
L
W
G
A
V
I
A
V
I
L
V
H
V
L
W
A
C
G
I
H
G
A
T
I
V
G
G
-
V
M
S
P
I
W
L
S
L
M
D
Q
N
R
I
A
F
Q
A
G
Q
D
V
P
N
T
I
T
A
Q
F
F
D
L
W
I
Y
M
G
G
S
G
A
T
L
A
L
V
V
-
G
M
L
L
F
-
A
R
S
Q
Q
L
K
S
L
G
R
L
S
I
A
P
G
I
F
N
I
N
E
M
V
T
F
G
M
P
I
-----
V
M
N
P
L
L
L
I
P
F
I
-----
V
V
P
V
V
L
T
I
V
S
Y
F
A
M
E
W
G
L
V
A
R
-
P
S
GA
A
V
--
T
W
T
T
P
I
L
F
S
G
Y
L
-
G
S
-
G
G
K
I
S
G
V
I
L
Q
L
V
N
F
A
L
A
F
V
I
Y
L
P
F
L
K
I
W
D
K
Q
K
I
A
E
E
K
G
E
A
-------
1
PsiBlast_PDB
95.72
28%
-136
- C4 -
3QNQ
8
?
A:
[5-425]
---------
L
E
K
Y
V
M
P
V
A
G
K
V
A
-
E
Q
R
H
L
L
A
I
R
D
G
L
V
L
T
M
P
F
L
I
I
G
S
I
F
L
I
I
S
T
L
P
I
P
G
Y
S
E
--
F
M
A
S
L
--
F
G
K
N
W
N
V
A
L
G
Y
P
V
S
A
T
F
N
I
M
A
L
I
A
V
F
G
I
A
Y
R
L
G
E
Y
Y
K
V
D
A
L
A
S
G
A
L
S
L
V
T
F
--
L
L
A
T
P
-
F
Q
V
A
-
Y
I
MP---
G
T
K
E
S
I
L
V
D
GV
I
P
A
A
--------
L
M
G
S
Q
G
L
F
V
A
M
I
I
A
I
I
S
T
E
I
Y
R
F
L
V
Q
K
K
M
-
I
I
K
M
P
E
T
V
P
P
A
V
T
R
S
F
A
A
L
I
P
G
F
I
V
V
T
V
V
W
I
I
R
L
I
F
E
H
-
T
T
F
G
S
I
H
N
V
V
G
K
-
L
L
Q
E
P
L
S
I
L
G
A
S
L
W
G
A
V
I
A
V
I
L
V
H
V
L
W
A
C
G
I
H
G
A
T
I
V
G
G
-
V
M
S
P
I
W
L
S
L
M
D
Q
N
R
I
A
F
Q
A
G
Q
D
V
P
N
T
I
T
A
Q
F
F
D
L
W
I
Y
M
G
G
S
G
A
T
L
A
L
V
V
G
M
L
-
L
F
-
A
R
S
Q
Q
L
K
S
L
G
R
L
S
I
A
P
G
I
F
N
I
N
E
M
V
T
F
G
M
P
I
-----
V
M
N
P
L
L
L
I
P
F
I
-----
V
V
P
V
V
L
T
I
V
S
Y
F
A
M
E
W
G
L
V
A
R
P
S
G
--
A
A
-
V
T
W
T
T
P
I
L
F
S
G
Y
L
G
S
G
-
G
-
K
I
S
G
V
I
L
Q
L
V
N
F
A
L
A
F
V
I
Y
L
P
F
L
K
I
W
D
K
Q
----------------
17
Fugue
40.82
21%
194
- C4 -
1W5K
-
GCN4_YEAST
A:
[2-34]
--------
R
M
R
Q
I
E
D
R
L
E
E
I
L
S
-
K
L
H
H
I
C
N
E
L
A
R
I
R
R
L
L
G
E
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
39.35
26%
-83
- C4 -
2YIU
3
CYB_PARDE
A:
[201-330]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
P
F
V
I
A
A
L
V
V
V
H
I
W
A
F
H
T
T
G
N
N
N
P
-
T
G
-
V
--
E
V
R
R
G
------
S
K
E
E
A
K
K
D
-----
T
L
P
F
W
P
Y
F
V
I
----
K
D
L
F
A
L
A
V
-
V
L
---------
V
V
F
F
A
I
V
G
F
M
P
N
Y
L
G
H
P
D
N
Y
I
E
A
N
P
L
VTPAH
I
V
P
E
W
Y
F
L
P
F
Y
A
I
L
RA
F
T
A
D
V
W
V
V
M
L
V
N
W
L
S
F
G
I
I
D
A
-
K
F
---------------------------------------------------------------------
24
Fugue
38.67
15%
165
- C4 -
1GZL
2
GCN4_YEAST
A:
[4-46]
--------
R
M
K
Q
I
E
D
K
I
E
E
I
E
S
-
K
Q
K
K
I
E
N
E
I
A
R
I
K
K
L
L
Q
L
T
V
W
G
I
K
Q
L
Q
A
R
I
L
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
37.52
25%
-67
- C4 -
2QJY
1
CYB_RHOSH
A:
[201-301]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
P
F
V
I
A
A
L
V
A
I
H
I
W
A
F
H
S
T
G
N
N
N
P
-
T
G
-
V
---------
E
V
R
R
T
S
K
A
E
A
Q
K
D
T
----
V
P
F
W
P
Y
F
I
I
----
K
D
V
F
A
L
A
V
-
V
L
---------
L
V
F
F
A
I
V
G
F
M
P
N
Y
L
G
H
P
D
N
Y
I
E
A
N
P
L
RTPAH
I
V
P
E
W
Y
F
L
P
F
---------------------------------------------------------------------------------------------------
18
Fugue
37.33
19%
294
- C4 -
1VTP
-
?
?:
[1-26]
---
S
E
Y
A
S
K
V
D
E
Y
V
G
E
V
E
N
D
L
Q
-
K
S
K
V
A
V
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
37.15
26%
-42
- C4 -
2QJP
3
CYB_RHOSH
A:
[199-284]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
P
F
V
I
A
A
L
V
A
I
H
I
W
A
F
H
S
T
G
N
N
N
P
-
T
G
-
V
---------
E
V
R
R
T
S
K
A
E
A
Q
K
D
T
----
V
P
F
W
P
Y
F
I
I
----
K
D
V
F
A
L
A
V
-
V
L
---------
L
V
F
F
A
I
V
G
F
M
P
N
Y
L
G
H
P
D
N
Y
I
E
A
N
P
L
------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
37.13
26%
-43
- C4 -
2QJK
1
CYB_RHOSH
A:
[199-284]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
P
F
V
I
A
A
L
V
A
I
H
I
W
A
F
H
S
T
G
N
N
N
P
-
T
G
-
V
---------
E
V
R
R
T
S
K
A
E
A
Q
K
D
T
----
V
P
F
W
P
Y
F
I
I
----
K
D
V
F
A
L
A
V
-
V
L
---------
L
V
F
F
A
I
V
G
F
M
P
N
Y
L
G
H
P
D
N
Y
I
E
A
N
P
L
------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
37.12
25%
-67
- C4 -
2FYN
2
CYB_RHOSH
A:
[201-301]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
P
F
V
I
A
A
L
V
A
I
H
I
W
A
F
H
S
T
G
N
N
N
P
-
T
G
-
V
---------
E
V
R
R
T
S
K
A
E
A
Q
K
D
T
----
V
P
F
W
P
Y
F
I
I
----
K
D
V
F
A
L
A
V
-
V
L
---------
L
V
F
F
A
I
V
G
F
M
P
N
Y
L
G
H
P
D
N
Y
I
E
A
N
P
L
RTPAH
I
V
P
E
W
Y
F
L
P
F
---------------------------------------------------------------------------------------------------
21
Fugue
36.58
17%
182
- C4 -
1ZTA
-
?
?:
[1-35]
------
L
Q
R
M
K
Q
L
E
D
K
V
E
E
L
L
S
-
K
N
Y
H
L
E
N
E
V
A
R
L
K
K
L
V
G
E
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
Fugue
35.88
11%
144
- C4 -
1G1J
1
NSP4_ROTS1
A:
[1-43]
-----
I
E
K
Q
M
D
R
V
V
K
E
M
R
R
Q
L
E
M
I
D
K
L
T
T
R
E
I
E
Q
V
E
L
L
K
R
I
Y
D
K
L
T
V
Q
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
35.80
14%
397
- C4 -
1LYP
-
A:
[5-25]
-
R
L
R
K
F
R
N
K
I
K
E
K
L
K
K
I
G
Q
K
I
Q
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
32.80
11%
447
- C4 -
1LBJ
-
A:
[1-18]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
V
P
I
F
T
Y
G
E
L
Q
R
M
Q
E
K
E
R
---------
12
HHSearch
30.64
31%
618
- C4 -
2KET
-
A:
[5-20]
-
R
F
R
K
K
F
K
K
L
F
K
K
L
S
P
V
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
Fugue
30.17
40%
593
* C4 *
3GP2
-
B:
[4-20]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
F
N
A
R
R
K
L
K
G
A
I
L
T
T
M
L
A
T
A
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
24.59
18%
403
- C4 -
2KNC
-
ITA2B_HUMAN
A:
[986-1007]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
M
W
K
V
G
F
F
K
R
N
R
P
P
L
E
E
D
D
E
E
G
--------
15
HHSearch
16.53
15%
590
- C3 -
2KBV
-
SL9A1_HUMAN
A:
[450-462]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
I
I
A
Y
G
G
L
R
G
A
I
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
10.38
36%
825
- C1 -
1G92
-
POTX_PARCV
A:
[2-12]
--------------------------------------
L
P
L
L
I
L
G
S
L
L
M
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------