@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0359: (2016-03-14 )
MLYTMKDLLAVGKEHQFAVPAFNICSFDMLKAIMEEVEANNAPVILEIHPDEIEYLGDNFVATVREYAYRSKVPVVIHMDHGGTIKDVMRAIRNGYTSVMIDASRASYEENVALTTQVVELAHKVGVSVEAELGTIGNNGSAEGGADTIIYTDPDQAEDFVSRTGIDTLAVAIGTAHGLYPKDKKPELNMPLLKELNKRLDIPFVLHGGSGNPDKEVSESVQYGVRKVNLSSDLKSVFFEEVRRVLVDNPAMYEPNQVYPSANEKVKDVVRHKLDILNTTGQADKY
Atome Classification :
(30 SA)
.........10........20........30........40........50......--..60.....-----...-70..--.......80........90........100.......110.......120.......130....-..-.140--.....---...150.......160.......170.......180.......190--.......200.......210-------------------...---------------------.---------------------.....220.......230.......240.......250.......260.......270.......280....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MLY
T
M
K
D
L
L
AVGKEHQFAV
P
A
F
N
IC
S
F
D
M
L
K
A
I
M
E
E
VEANNA
P
V
I
L
E
IHP
D
E
I
E
Y
LG--
D
N
F
V
A
T
V
R
E
-----
Y
A
Y-R-SK--V
P
V
V
I
H
MDHGG
T
I
K
D
V
M
R
A
I
RNGY
T
S
V
M
I
DASRASYEEN
V
A
L
T
T
Q
V
V
E
L
A
H
KVG
V
S
V
E
A
E
LGTI-GN-NGS---AEGGA---
D
T
I
I
Y
TD
P
D
Q
A
E
D
F
V
S
RTG
I
D
T
L
A
V
A
I
GTAHGLYPKDKKPELN
M
P
L
--
L
K
E
L
N
K
RLDI
P
F
V
L
HGGS---------------------GN
P
---------------------
D
---------------------
K
E
V
S
E
S
V
Q
Y
G
V
RKVN
L
S
S
D
L
K
S
V
F
F
E
E
V
R
R
V
LVDNPAMYEPNQVYPSA
N
E
K
V
K
D
V
V
R
H
K
L
D
I
LNTTGQADKY
34
PsiBlast_CBE
95.31
33%
-100
- C3 -
3C56
3
ALF_HELPY
B:
[1-306]
M
L
V
K
G
N
E
I
L
L
K
A
H
K
E
G
Y
G
V
G
A
F
N
F
V
N
F
E
M
L
N
A
I
F
E
A
G
N
E
E
N
S
P
L
F
I
Q
A
S
E
G
A
I
K
Y
M
G
I
-
D
M
A
V
G
M
V
K
I
-----
M
C
E
-
R
Y
P
H
--
I
P
V
A
L
H
L
D
H
G
T
T
F
E
S
C
E
K
A
V
K
A
G
F
T
S
V
M
I
D
A
S
H
H
A
F
E
E
N
L
E
L
T
S
K
V
V
K
M
A
H
N
A
G
V
S
V
E
A
E
L
G
R
L
M--------------------
V
L
V
N
P
K
E
A
E
Q
F
V
K
E
S
Q
V
D
Y
L
A
P
A
I
G
T
S
H
G
A
F
K
F
K
G
E
P
K
L
D
F
E
R
--
L
Q
E
V
K
R
L
T
N
I
P
L
V
L
H
G
A
S
---------------------
A
I
P
---------------------
D
N
V
R
K
S
Y
L
D
A
GGDLKGSKGVP
F
E
F
L
Q
E
S
V
K
G
G
I
N
K
V
N
T
D
T
D
L
R
I
A
F
I
A
E
V
R
K
V
A
N
E
D
K
S
Q
F
D
L
R
K
F
F
S
P
A
Q
L
A
L
K
N
V
V
K
E
R
M
K
L
L
G
S
A
N
K
----
7
PsiBlast_PDB
95.08
33%
-98
- C3 -
3N9R
4
?
A:
[1-306]
M
L
V
K
G
N
E
I
L
L
K
A
H
K
E
G
Y
G
V
G
A
F
N
F
V
N
F
E
M
L
N
A
I
F
E
A
G
N
E
E
N
S
P
L
F
I
Q
A
S
E
G
A
I
K
Y
M
G
I
-
D
M
A
V
G
M
V
K
I
-----
M
C
E
-
R
Y
P
H
--
I
P
V
A
L
H
L
D
H
G
T
T
F
E
S
C
E
K
A
V
K
A
G
F
T
S
V
M
I
D
A
S
H
H
A
F
E
E
N
L
E
L
T
S
K
V
V
K
M
A
H
N
A
G
V
S
V
E
A
E
L
G
R
L
M
G
I
-----------------
A
V
L
V
N
P
K
E
A
E
Q
F
V
K
E
S
Q
V
D
Y
L
A
P
A
I
G
T
S
H
G
A
F
K
F
K
G
E
P
K
L
D
F
E
R
--
L
Q
E
V
K
R
L
T
N
I
P
L
V
L
H
G
A
S
---------------------
A
I
P
---------------------
D
N
V
R
K
S
Y
L
D
A
GGDLKGSKGVP
F
E
F
L
Q
E
S
V
K
G
G
I
N
K
V
N
T
D
T
D
L
R
I
A
F
I
A
E
V
R
K
V
A
N
E
D
K
S
Q
F
D
L
R
K
F
F
S
P
A
Q
L
A
L
K
N
V
V
K
E
R
M
K
L
L
G
S
A
N
K
----
31
PsiBlast_CBE
94.85
33%
-98
- C3 -
3N9R
4
?
P:
[1-306]
M
L
V
K
G
N
E
I
L
L
K
A
H
K
E
G
Y
G
V
G
A
F
N
F
V
N
F
E
M
L
N
A
I
F
E
A
G
N
E
E
N
S
P
L
F
I
Q
A
S
E
G
A
I
K
Y
M
G
I-
D
M
A
V
G
M
V
K
I
-----
M
C
E
-
R
Y
P
H
--
I
P
V
A
L
H
L
D
H
G
T
T
F
E
S
C
E
K
A
V
K
A
G
F
T
S
V
M
I
D
A
S
H
H
A
F
E
E
N
L
E
L
T
S
K
V
V
K
M
A
H
N
A
G
V
S
V
E
A
E
L
G
R
L
M
G
I
-----------------
A
V
L
V
N
P
K
E
A
E
Q
F
V
K
E
S
Q
V
D
Y
L
A
P
A
I
G
T
S
H
G
A
F
K
F
K
G
E
P
K
L
D
F
E
R
--
L
Q
E
V
K
R
L
T
N
I
P
L
V
L
H
G
A
S
---------------------
A
I
P
---------------------
D
NVRKSYLDAGGDLKGSKGVPF
E
F
L
Q
E
S
V
K
G
G
I
N
K
V
N
T
D
T
D
L
R
I
A
F
I
A
E
V
R
K
V
A
N
E
D
K
S
Q
F
D
L
R
K
F
F
S
P
A
Q
L
A
L
K
N
V
V
K
E
R
M
K
L
L
G
S
A
N
K
----
30
PsiBlast_CBE
94.75
33%
-95
- C3 -
3N9R
2
?
U:
[1-306]
M
L
V
K
G
N
E
I
L
L
K
A
H
K
E
G
Y
G
V
G
A
F
N
F
V
N
F
E
M
L
N
A
I
F
E
A
G
N
E
E
N
S
P
L
F
I
Q
A
S
E
G
A
I
K
Y
M
G
I-
D
M
A
V
G
M
V
K
I
-----
M
C
E
-
R
Y
P
H
--
I
P
V
A
L
H
L
D
H
G
T
T
F
E
S
C
E
K
A
V
K
A
G
F
T
S
V
M
I
D
A
S
H
H
A
F
E
E
N
L
E
L
T
S
K
V
V
K
M
A
H
N
A
G
V
S
V
E
A
E
L
G
R
L
M
G
I
-----------------
A
V
L
V
N
P
K
E
A
E
Q
F
V
K
E
S
Q
V
D
Y
L
A
P
A
I
G
T
S
H
G
A
F
K
F
K
G
E
P
K
L
D
F
E
R
--
L
Q
E
V
K
R
L
T
N
I
P
L
V
L
H
G
A
S
---------------------
A
I
P
---------------------
D
NVRKSYLDAGGDLKGSKGVPF
E
F
L
Q
E
S
V
K
G
G
I
N
K
V
N
T
D
T
D
L
R
I
A
F
I
A
E
V
R
K
V
A
N
E
D
K
S
Q
F
D
L
R
K
F
F
S
P
A
Q
L
A
L
K
N
V
V
K
E
R
M
K
L
L
G
S
A
N
K
----
28
PsiBlast_CBE
94.48
33%
-97
- C3 -
3N9S
5
?
B:
[1-306]
M
L
V
K
G
N
E
I
L
L
K
A
H
K
E
G
Y
G
V
G
A
F
N
F
V
N
F
E
M
L
N
A
I
F
E
A
G
N
E
E
N
S
P
L
F
I
Q
A
S
E
G
A
I
K
Y
M
G
I
-
D
M
A
V
G
M
V
K
I
-----
M
C
E
-
R
Y
P
H
--
I
P
V
A
L
H
L
D
H
G
T
T
F
E
S
C
E
K
A
V
K
A
G
F
T
S
V
M
I
D
A
S
H
H
A
F
E
E
N
L
E
L
T
S
K
V
V
K
M
A
H
N
A
G
V
S
V
E
A
E
L
G
R
L
M-------------------
A
V
L
V
N
P
K
E
A
E
Q
F
V
K
E
S
Q
V
D
Y
L
A
P
A
I
G
T
S
H
G
A
F
K
F
K
G
E
P
K
L
D
F
E
R
--
L
Q
E
V
K
R
L
T
N
I
P
L
V
L
H
G
A
S
---------------------
A
I
P
---------------------
D
N
V
R
K
S
Y
L
D
A
GGDLKGSKGVP
F
E
F
L
Q
E
S
V
K
G
G
I
N
K
V
N
T
D
T
D
L
R
I
A
F
I
A
E
V
R
K
V
A
N
E
D
K
S
Q
F
D
L
R
K
F
F
S
P
A
Q
L
A
L
K
N
V
V
K
E
R
M
K
L
L
G
S
A
N
K
----
32
PsiBlast_CBE
94.44
33%
-95
- C3 -
3N9R
4
?
K:
[1-306]
M
L
V
K
G
N
E
I
L
L
K
A
H
K
E
G
Y
G
V
G
A
F
N
F
V
N
F
E
M
L
N
A
I
F
E
A
G
N
E
E
N
S
P
L
F
I
Q
A
S
E
G
A
I
K
Y
M
G
I-
D
M
A
V
G
M
V
K
I
-----
M
C
E
-
R
Y
P
H
--
I
P
V
A
L
H
L
D
H
G
T
T
F
E
S
C
E
K
A
V
K
A
G
F
T
S
V
M
I
D
A
S
H
H
A
F
E
E
N
L
E
L
T
S
K
V
V
K
M
A
H
N
A
G
V
S
V
E
A
E
L
G
R
L
M
G
I
-----------------
A
V
L
V
N
P
K
E
A
E
Q
F
V
K
E
S
Q
V
D
Y
L
A
P
A
I
G
T
S
H
G
A
F
K
F
K
G
E
P
K
L
D
F
E
R
--
L
Q
E
V
K
R
L
T
N
I
P
L
V
L
H
G
A
S
---------------------
A
I
P
---------------------
D
NVRKSYLDAGGDLKGSKGVPF
E
F
L
Q
E
S
V
K
G
G
I
N
K
V
N
T
D
T
D
L
R
I
A
F
I
A
E
V
R
K
V
A
N
E
D
K
S
Q
F
D
L
R
K
F
F
S
P
A
Q
L
A
L
K
N
V
V
K
E
R
M
K
L
L
G
S
A
N
K
----
29
PsiBlast_CBE
94.19
33%
-97
- C3 -
3N9R
14
?
Z:
[1-306]
M
L
V
K
G
N
E
I
L
L
K
A
H
K
E
G
Y
G
V
G
A
F
N
F
V
N
F
E
M
L
N
A
I
F
E
A
G
N
E
E
N
S
P
L
F
I
Q
A
S
E
G
A
I
K
Y
M
G
I-
D
M
A
V
G
M
V
K
I
-----
M
C
E
-
R
Y
P
H
--
I
P
V
A
L
H
L
D
H
G
T
T
F
E
S
C
E
K
A
V
K
A
G
F
T
S
V
M
I
D
A
S
H
H
A
F
E
E
N
L
E
L
T
S
K
V
V
K
M
A
H
N
A
G
V
S
V
E
A
E
L
G
R
L
M
G
I
-----------------
A
V
L
V
N
P
K
E
A
E
Q
F
V
K
E
S
Q
V
D
Y
L
A
P
A
I
G
T
S
H
G
A
F
K
F
K
G
E
P
K
L
D
F
E
R
--
L
Q
E
V
K
R
L
T
N
I
P
L
V
L
H
G
A
S
---------------------
A
I
P
---------------------
D
NVRKSYLDAGGDLKGSKGVPF
E
F
L
Q
E
S
V
K
G
G
I
N
K
V
N
T
D
T
D
L
R
I
A
F
I
A
E
V
R
K
V
A
N
E
D
K
S
Q
F
D
L
R
K
F
F
S
P
A
Q
L
A
L
K
N
V
V
K
E
R
M
K
L
L
G
S
A
N
K
----
35
PsiBlast_CBE
94.18
33%
-98
- C3 -
3C4U
2
ALF_HELPY
B:
[1-306]
M
L
V
K
G
N
E
I
L
L
K
A
H
K
E
G
Y
G
V
G
A
F
N
F
V
N
F
E
M
L
N
A
I
F
E
A
G
N
E
E
N
S
P
L
F
I
Q
A
S
E
G
A
I
K
Y
M
G
I-
D
M
A
V
G
M
V
K
I
-----
M
C
E
-
R
Y
P
H
--
I
P
V
A
L
H
L
D
H
G
T
T
F
E
S
C
E
K
A
V
K
A
G
F
T
S
V
M
I
D
A
S
H
H
A
F
E
E
N
L
E
L
T
S
K
V
V
K
M
A
H
N
A
G
V
S
V
E
A
E
L
G
R
----------------------
V
L
V
N
P
K
E
A
E
Q
F
V
K
E
S
Q
V
D
Y
L
A
P
A
I
G
T
S
H
G
A
F
K
F
K
G
E
P
K
L
D
F
E
R
--
L
Q
E
V
K
R
L
T
N
I
P
L
V
L
H
G
A
S
---------------------
A
I
P
---------------------
D
NVRKSYLDAGGDLKGSKGVPF
E
F
L
Q
E
S
V
K
G
G
I
N
K
V
N
T
D
T
D
L
R
I
A
F
I
A
E
V
R
K
V
A
N
E
D
K
S
Q
F
D
L
R
K
F
F
S
P
A
Q
L
A
L
K
N
V
V
K
E
R
M
K
L
L
G
S
A
N
K
----
33
PsiBlast_CBE
94.05
33%
-95
- C3 -
3N9R
4
?
B:
[1-306]
M
L
V
K
G
N
E
I
L
L
K
A
H
K
E
G
Y
G
V
G
A
F
N
F
V
N
F
E
M
L
N
A
I
F
E
A
G
N
E
E
N
S
P
L
F
I
Q
A
S
E
G
A
I
K
Y
M
G
I-
D
M
A
V
G
M
V
K
I
-----
M
C
E
-
R
Y
P
H
--
I
P
V
A
L
H
L
D
H
G
T
T
F
E
S
C
E
K
A
V
K
A
G
F
T
S
V
M
I
D
A
S
H
H
A
F
E
E
N
L
E
L
T
S
K
V
V
K
M
A
H
N
A
G
V
S
V
E
A
E
L
G
R
L
M
G
I
-----------------
A
V
L
V
N
P
K
E
A
E
Q
F
V
K
E
S
Q
V
D
Y
L
A
P
A
I
G
T
S
H
G
A
F
K
F
K
G
E
P
K
L
D
F
E
R
--
L
Q
E
V
K
R
L
T
N
I
P
L
V
L
H
G
A
S
---------------------
A
I
P
---------------------
D
NVRKSYLDAGGDLKGSKGVPF
E
F
L
Q
E
S
V
K
G
G
I
N
K
V
N
T
D
T
D
L
R
I
A
F
I
A
E
V
R
K
V
A
N
E
D
K
S
Q
F
D
L
R
K
F
F
S
P
A
Q
L
A
L
K
N
V
V
K
E
R
M
K
L
L
G
S
A
N
K
----
5
PsiBlast_PDB
93.76
33%
-95
- C3 -
3C52
4
ALF_HELPY
A:
[1-306]
M
L
V
K
G
N
E
I
L
L
K
A
H
K
E
G
Y
G
V
G
A
F
N
F
V
N
F
E
M
L
N
A
I
F
E
A
G
N
E
E
N
S
P
L
F
I
Q
A
S
E
G
A
I
K
Y
M
G
I
-
D
M
A
V
G
M
V
K
I
-----
M
C
E
-
R
Y
P
H
--
I
P
V
A
L
H
L
D
H
G
T
T
F
E
S
C
E
K
A
V
K
A
G
F
T
S
V
M
I
D
A
S
H
H
A
F
E
E
N
L
E
L
T
S
K
V
V
K
M
A
H
N
A
G
V
S
V
E
A
E
L
G
R
L
M
G
I
------------------
V
L
V
N
P
K
E
A
E
Q
F
V
K
E
S
Q
V
D
Y
L
A
P
A
I
G
T
S
H
G
A
F
K
F
K
G
E
P
K
L
D
F
E
R
--
L
Q
E
V
K
R
L
T
N
I
P
L
V
L
H
G
A
S
---------------------
A
I
P
---------------------
D
N
V
R
K
S
Y
L
D
A
G
G
D
L
K
GSKGVP
F
E
F
L
Q
E
S
V
K
G
G
I
N
K
V
N
T
D
T
D
L
R
I
A
F
I
A
E
V
R
K
V
A
N
E
D
K
S
Q
F
D
L
R
K
F
F
S
P
A
Q
L
A
L
K
N
V
V
K
E
R
M
K
L
L
G
S
A
N
K
----
4
PsiBlast_PDB
93.67
33%
-100
- C3 -
3C4U
2
ALF_HELPY
A:
[1-306]
M
L
V
K
G
N
E
I
L
L
K
A
H
K
E
G
Y
G
V
G
A
F
N
F
V
N
F
E
M
L
N
A
I
F
E
A
G
N
E
E
N
S
P
L
F
I
Q
A
S
E
G
A
I
K
Y
M
G
I
-
D
M
A
V
G
M
V
K
I
-----
M
C
E
-
R
Y
P
H
--
I
P
V
A
L
H
L
D
H
G
T
T
F
E
S
C
E
K
A
V
K
A
G
F
T
S
V
M
I
D
A
S
H
H
A
F
E
E
N
L
E
L
T
S
K
V
V
K
M
A
H
N
A
G
V
S
V
E
A
E
L
G
R
----------------------
V
L
V
N
P
K
E
A
E
Q
F
V
K
E
S
Q
V
D
Y
L
A
P
A
I
G
T
S
H
G
A
F
K
F
K
G
E
P
K
L
D
F
E
R
--
L
Q
E
V
K
R
L
T
N
I
P
L
V
L
H
G
A
S
---------------------
A
I
P
---------------------
D
N
V
R
K
S
Y
L
D
A
GGDLKGSKGVP
F
E
F
L
Q
E
S
V
K
G
G
I
N
K
V
N
T
D
T
D
L
R
I
A
F
I
A
E
V
R
K
V
A
N
E
D
K
S
Q
F
D
L
R
K
F
F
S
P
A
Q
L
A
L
K
N
V
V
K
E
R
M
K
L
L
G
S
A
N
K
----
41
HHSearch
93.51
35%
-102
- C3 -
1GVF
11
KBAY_ECOLI
A:
[2-285]
S
I
I
S
T
K
Y
L
L
Q
D
A
Q
A
N
G
Y
A
V
P
A
F
N
I
H
N
A
E
T
I
Q
A
I
L
E
V
C
S
E
M
R
S
P
V
I
L
A
G
T
P
G
T
F
K
H
I
A
L
-
E
E
I
Y
A
L
C
S
A
-----
Y
S
T
-
T
-
Y
N
--
M
P
L
A
L
H
L
D
H
H
E
S
L
D
D
I
R
R
K
V
H
A
G
V
R
S
A
M
I
D
G
S
H
F
P
F
A
E
N
V
K
L
V
K
S
V
V
D
F
C
H
S
Q
D
C
S
V
E
A
E
L
G
R
L
-
G
-----------------
S
A
F
L
T
D
P
Q
E
A
K
R
F
V
E
L
T
G
V
D
S
L
A
V
A
I
G
T
A
H
G
L
Y
S
--
K
T
P
K
I
D
F
Q
R
--
L
A
E
I
R
E
V
V
D
V
P
L
V
L
H
G
A
S
---------------------
D
V
P
---------------------
D
---------------------
E
F
V
R
R
T
I
E
L
G
V
T
K
V
N
V
A
T
E
L
K
I
A
F
A
G
A
V
K
A
W
F
A
E
N
P
Q
G
N
D
P
R
Y
Y
M
R
V
G
M
D
A
M
K
E
V
V
R
N
K
I
N
V
C
G
S
A
N
R
I
S
--
6
PsiBlast_PDB
93.32
33%
-97
- C3 -
3C56
3
ALF_HELPY
A:
[1-306]
M
L
V
K
G
N
E
I
L
L
K
A
H
K
E
G
Y
G
V
G
A
F
N
F
V
N
F
E
M
L
N
A
I
F
E
A
G
N
E
E
N
S
P
L
F
I
Q
A
S
E
G
A
I
K
Y
M
G
I
-
D
M
A
V
G
M
V
K
I
-----
M
C
E
-
R
Y
P
H
--
I
P
V
A
L
H
L
D
H
G
T
T
F
E
S
C
E
K
A
V
K
A
G
F
T
S
V
M
I
D
A
S
H
H
A
F
E
E
N
L
E
L
T
S
K
V
V
K
M
A
H
N
A
G
V
S
V
E
A
E
L
G
R
L
M
G
I
-----------------
A
V
L
V
N
P
K
E
A
E
Q
F
V
K
E
S
Q
V
D
Y
L
A
P
A
I
G
T
S
H
G
A
F
K
F
K
G
E
P
K
L
D
F
E
R
--
L
Q
E
V
K
R
L
T
N
I
P
L
V
L
H
G
A
S
---------------------
A
I
P
---------------------
D
N
V
R
K
S
Y
L
D
A
GGDLKGSKGVP
F
E
F
L
Q
E
S
V
K
G
G
I
N
K
V
N
T
D
T
D
L
R
I
A
F
I
A
E
V
R
K
V
A
N
E
D
K
S
Q
F
D
L
R
K
F
F
S
P
A
Q
L
A
L
K
N
V
V
K
E
R
M
K
L
L
G
S
A
N
K
----
27
PsiBlast_CBE
93.28
34%
-100
- C3 -
1RV8
6
?
B:
[1-305]
M
L
V
T
G
L
E
I
L
K
K
A
R
E
E
G
Y
G
V
G
A
F
N
V
N
N
M
E
F
L
Q
A
V
L
E
A
A
E
E
Q
R
S
P
V
I
L
A
L
S
E
G
A
M
K
Y
G
G
--
R
A
L
T
L
M
A
V
E
-----
L
A
K
-
E
-
A
R
--
V
P
V
A
V
H
L
D
H
G
S
S
Y
E
S
V
L
R
A
L
R
A
G
F
T
S
V
M
I
D
K
S
H
E
D
F
E
T
N
V
R
E
T
R
R
V
V
E
A
A
H
A
V
G
V
T
V
E
A
E
L
G
R
L
-
A
---
G
I
---
E
E
H
V
A
VD
E
K
D
A
L
L
T
N
P
E
E
A
R
I
F
M
E
R
T
G
A
D
Y
L
A
V
A
I
G
T
S
H
G
A
Y
K
G
K
G
R
P
F
I
D
H
A
R
--
L
E
R
I
A
R
L
V
P
A
P
L
V
L
H
G
A
S
---------------------
A
V
P
P
E
L
V
E
R
F
R
A
S
G
G
E
I
G
E
A
A
G
I
H
P
---------------------
E
D
I
K
K
A
I
S
L
G
I
A
K
I
N
T
D
T
D
L
R
L
A
F
T
A
L
I
R
E
A
L
N
K
N
P
K
E
F
D
P
R
K
Y
L
G
P
A
R
E
A
V
K
E
V
V
K
S
R
M
E
L
F
G
S
V
G
R
A
---
23
PsiBlast_CBE
93.23
34%
-98
- C3 -
1RVG
6
?
C:
[1-305]
M
L
V
T
G
L
E
I
L
K
K
A
R
E
E
G
Y
G
V
G
A
F
N
V
N
N
M
E
F
L
Q
A
V
L
E
A
A
E
E
Q
R
S
P
V
I
L
A
L
S
E
G
A
M
K
Y
G
G
--
R
A
L
T
L
M
A
V
E
-----
L
A
K
-
E
-
A
R
--
V
P
V
A
V
H
L
D
H
G
S
S
Y
E
S
V
L
R
A
L
R
A
G
F
T
S
V
M
I
D
K
S
H
E
D
F
E
T
N
V
R
E
T
R
R
V
V
E
A
A
H
A
V
G
V
T
V
E
A
E
L
G
R
L
-
A
---
G
I
---
E
E
H
V
A
VDE
K
D
A
L
L
T
N
P
E
E
A
R
I
F
M
E
R
T
G
A
D
Y
L
A
V
A
I
G
T
S
H
G
A
Y
K
G
K
G
R
P
F
I
D
H
A
R
--
L
E
R
I
A
R
L
V
P
A
P
L
V
L
H
G
A
S
---------------------
A
V
P
PELVERFRASGGEIGEAAGIH
P
---------------------
E
D
I
K
K
A
I
S
L
G
I
A
K
I
N
T
D
T
D
L
R
L
A
F
T
A
L
I
R
E
A
L
N
K
N
P
K
E
F
D
P
R
K
Y
L
G
P
A
R
E
A
V
K
E
V
V
K
S
R
M
E
L
F
G
S
V
G
R
A
---
25
PsiBlast_CBE
92.91
34%
-98
- C3 -
1RV8
6
?
D:
[1-305]
M
L
V
T
G
L
E
I
L
K
K
A
R
E
E
G
Y
G
V
G
A
F
N
V
N
N
M
E
F
L
Q
A
V
L
E
A
A
E
E
Q
R
S
P
V
I
L
A
L
S
E
G
A
M
K
Y
G
G
--
R
A
L
T
L
M
A
V
E
-----
L
A
K
-
E
-
A
R
--
V
P
V
A
V
H
L
D
H
G
S
S
Y
E
S
V
L
R
A
L
R
A
G
F
T
S
V
M
I
D
K
S
H
E
D
F
E
T
N
V
R
E
T
R
R
V
V
E
A
A
H
A
V
G
V
T
V
E
A
E
L
G
R
L
-
A
---
G
I
---
E
E
H
V
A
VDE
K
D
A
L
L
T
N
P
E
E
A
R
I
F
M
E
R
T
G
A
D
Y
L
A
V
A
I
G
T
S
H
G
A
Y
K
G
K
G
R
P
F
I
D
H
A
R
--
L
E
R
I
A
R
L
V
P
A
P
L
V
L
H
G
A
S
---------------------
A
V
P
PELVERFRASGGEIGEAAGIH
P
---------------------
E
D
I
K
K
A
I
S
L
G
I
A
K
I
N
T
D
T
D
L
R
L
A
F
T
A
L
I
R
E
A
L
N
K
N
P
K
E
F
D
P
R
K
Y
L
G
P
A
R
E
A
V
K
E
V
V
K
S
R
M
E
L
F
G
S
V
G
R
A
---
26
PsiBlast_CBE
92.85
34%
-96
- C3 -
1RV8
6
?
C:
[1-305]
M
L
V
T
G
L
E
I
L
K
K
A
R
E
E
G
Y
G
V
G
A
F
N
V
N
N
M
E
F
L
Q
A
V
L
E
A
A
E
E
Q
R
S
P
V
I
L
A
L
S
E
G
A
M
K
Y
G
G
--
R
A
L
T
L
M
A
V
E
-----
L
A
K
-
E
-
A
R
--
V
P
V
A
V
H
L
D
H
G
S
S
Y
E
S
V
L
R
A
L
R
A
G
F
T
S
V
M
I
D
K
S
H
E
D
F
E
T
N
V
R
E
T
R
R
V
V
E
A
A
H
A
V
G
V
T
V
E
A
E
L
G
R
L
-
A
---
G
I
---
E
E
H
V
A
VDE
K
D
A
L
L
T
N
P
E
E
A
R
I
F
M
E
R
T
G
A
D
Y
L
A
V
A
I
G
T
S
H
G
A
Y
K
G
K
G
R
P
F
I
D
H
A
R
--
L
E
R
I
A
R
L
V
P
A
P
L
V
L
H
G
A
S
---------------------
A
V
P
PELVERFRASGGEIGEAAGIH
P
---------------------
E
D
I
K
K
A
I
S
L
G
I
A
K
I
N
T
D
T
D
L
R
L
A
F
T
A
L
I
R
E
A
L
N
K
N
P
K
E
F
D
P
R
K
Y
L
G
P
A
R
E
A
V
K
E
V
V
K
S
R
M
E
L
F
G
S
V
G
R
A
---
22
PsiBlast_CBE
92.57
34%
-95
- C3 -
1RVG
5
?
D:
[1-305]
M
L
V
T
G
L
E
I
L
K
K
A
R
E
E
G
Y
G
V
G
A
F
N
V
N
N
M
E
F
L
Q
A
V
L
E
A
A
E
E
Q
R
S
P
V
I
L
A
L
S
E
G
A
M
K
Y
G
G
--
R
A
L
T
L
M
A
V
E
-----
L
A
K
-
E
-
A
R
--
V
P
V
A
V
H
L
D
H
G
S
S
Y
E
S
V
L
R
A
L
R
A
G
F
T
S
V
M
I
D
K
S
H
E
D
F
E
T
N
V
R
E
T
R
R
V
V
E
A
A
H
A
V
G
V
T
V
E
A
E
L
G
R
L
-
A
---
G
I
---
E
E
H
V
A
VDE
K
D
A
L
L
T
N
P
E
E
A
R
I
F
M
E
R
T
G
A
D
Y
L
A
V
A
I
G
T
S
H
G
A
Y
K
G
K
G
R
P
F
I
D
H
A
R
--
L
E
R
I
A
R
L
V
P
A
P
L
V
L
H
G
A
S
---------------------
A
V
P
PELVERFRASGGEIGEAAGIH
P
---------------------
E
D
I
K
K
A
I
S
L
G
I
A
K
I
N
T
D
T
D
L
R
L
A
F
T
A
L
I
R
E
A
L
N
K
N
P
K
E
F
D
P
R
K
Y
L
G
P
A
R
E
A
V
K
E
V
V
K
S
R
M
E
L
F
G
S
V
G
R
A
---
24
PsiBlast_CBE
92.49
34%
-98
- C3 -
1RVG
6
?
B:
[1-305]
M
L
V
T
G
L
E
I
L
K
K
A
R
E
E
G
Y
G
V
G
A
F
N
V
N
N
M
E
F
L
Q
A
V
L
E
A
A
E
E
Q
R
S
P
V
I
L
A
L
S
E
G
A
M
K
Y
G
G
--
R
A
L
T
L
M
A
V
E
-----
L
A
K
-
E
-
A
R
--
V
P
V
A
V
H
L
D
H
G
S
S
Y
E
S
V
L
R
A
L
R
A
G
F
T
S
V
M
I
D
K
S
H
E
D
F
E
T
N
V
R
E
T
R
R
V
V
E
A
A
H
A
V
G
V
T
V
E
A
E
L
G
R
L
-
A
---
G
I
---
E
E
H
V
A
VDE
K
D
A
L
L
T
N
P
E
E
A
R
I
F
M
E
R
T
G
A
D
Y
L
A
V
A
I
G
T
S
H
G
A
Y
K
G
K
G
R
P
F
I
D
H
A
R
--
L
E
R
I
A
R
L
V
P
A
P
L
V
L
H
G
A
S
---------------------
A
V
P
P
E
L
V
E
R
F
R
A
S
G
G
E
I
G
E
A
A
G
I
H
P
---------------------
E
D
I
K
K
A
I
S
L
G
I
A
K
I
N
T
D
T
D
L
R
L
A
F
T
A
L
I
R
E
A
L
N
K
N
P
K
E
F
D
P
R
K
Y
L
G
P
A
R
E
A
V
K
E
V
V
K
S
R
M
E
L
F
G
S
V
G
R
A
---
39
HHSearch
92.40
37%
-85
- C3 -
1RVG
8
?
A:
[1-305]
M
L
V
T
G
L
E
I
L
K
K
A
R
E
E
G
Y
G
V
G
A
F
N
V
N
N
M
E
F
L
Q
A
V
L
E
A
A
E
E
Q
R
S
P
V
I
L
A
L
S
E
G
A
M
K
Y
G
G
--
R
A
L
T
L
M
A
V
E
-----
L
A
K
-
E
-
A
R
--
V
P
V
A
V
H
L
D
H
G
S
S
Y
E
S
V
L
R
A
L
R
A
G
F
T
S
V
M
I
D
K
S
H
E
D
F
E
T
N
V
R
E
T
R
R
V
V
E
A
A
H
A
V
G
V
T
V
E
A
E
L
G
R
L
-
A
G
-
I
E
E
-----------
K
D
A
L
L
T
N
P
E
E
A
R
I
F
M
E
R
T
G
A
D
Y
L
A
V
A
I
G
T
S
H
G
A
Y
K
G
K
G
R
P
F
I
D
H
A
R
--
L
E
R
I
A
R
L
V
P
A
P
L
V
L
H
G
A
S
AVP
P
E
L
V
E
R
F
R
A
S
G
G
E
I
G
EAA
G
I
H
---------------------
P
---------------------
E
D
I
K
K
A
I
S
L
G
I
A
K
I
N
T
D
T
D
L
R
L
A
F
T
A
L
I
R
E
A
L
N
K
N
P
K
E
F
D
P
R
K
Y
L
G
P
A
R
E
A
V
K
E
V
V
K
S
R
M
E
L
F
G
S
V
G
R
A
---