@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0433: (2016-03-15 )
VRKKRYVWLKSILVAILVFGSGVWINTSNGTNAQAATITQDTPINQIFTDTALAEKMKTVLGKTNVTDTVSQTDLDQVTTLQADRLGIKSIDGVEYLNNLTQINFSNNQLTDITPLKNLTKLVDILMNNNQIADITPLANLTNLTGLTLFNNQITDIDPLKNLTNLNRLELSSNTISDISALSGLTSLQQLSFGNQVTDLKPLANLTTLERLDISSNKVSDISVLAKLTNLESLIATNNQISDITPLGILTNLDELSLNGNQLKDIGTLASLTNLTDLDLANNQISNLAPLSGLTKLTELKLGANQISNISPLAGLTALTNLELNENQLEDISPISNLKNLTYLTLYFNNISDISPVSSLTKLQRLFFYNNKVSDVSSLANLTNINWLSAGHNQISDLTPLANLTRITQLGLNDQAWTNAPVNYKANVSIPNTVKNVTGALIAPATISDGGSYTEPDITWNLPSYTNEVSYTFSQPVTIGKGTTTFSGTVTQPLKAIFNVKFHVDGKETTKEVEAGNLLTEPAKPVKEGHTFVGWFDAQTGGTKWNFSTDKMPTNDINLYAQFSINSYTATFDNDGVTTSQTVDYQGLLQEPTAPTKEGYTFKGWYDAKTGGDKWDFATSKMPAKNITLYAQYSANSYTATFDVDGKSTTQAVDYQGLLKEPKAPTKAGYTFKGWYDEKTDGKKWDFATDKMPANDITLYAQFTKNPVAPPTTGGNTPPTTNNGGNTTPPSANIPGSDTSNTSTGNSASTTSTMNAYDPYNSKEASLPTTGDSDNALYLLLGLLAVGTAMALTKKARASK
Atome Classification :
(20 SA)
.........10........20........30.......-.40........50........60........70........80........90........100.......110.......120.......130.....--..140.......150.....--..160.......170..-.....180.......190.-.-.....200.......210.......220--.......230.......240.......---250.......260.......270.......280.......290.......300.......310.......320.......--330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.----------......580..---.....--590.......600..---.....610---------.......620..-.....630.---....-..640....-...650.....----..660.......670.------......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
VRK
K
R
Y
V
W
L
K
S
I
L
V
A
I
L
VFGS
G
V
W
I
NTSNGTNA
Q
A
A
T
I-TQDTP
I
N
Q
I
F
T
D
T
A
L
A
E
K
M
K
T
V
LGKTNVTDTVSQT
D
L
D
Q
V
T
T
LQADRLGIKSID
G
V
E
Y
L
N
N
L
T
Q
I
NFSNNQLTDIT
P
L
K
N
L
T
K
L
V
D
I
L
MNNNQIADITP--LANLTNL
T
G
L
T
L
FNNQITDI--D
P
L
K
N
LTNL
N
R
L
ELSSN-
T
I
S
D
I
S
A
L
S
G
L
T
S
L
Q
Q
LSF-G-NQVTDLKPLANL
T
T
L
E
R
LDISSNK
V
S
D
I
--
S
V
L
A
K
L
T
N
L
E
S
L
I
ATNNQISDITP
L
G
I
---LT
N
L
D
E
LSLNG
N
Q
L
K
D
I
G
T
L
A
S
LTNLTDLDLANNQISNLAPLS
G
L
T
K
L
T
E
LKL
G
A
N
QISNISPLAG
L
T
A
L
T
NLELNENQL--EDIS
P
I
SNLKN
L
T
Y
L
T
L
Y
FNNISDIS
P
V
S
S
L
T
K
L
Q
R
L
F
F
YNNKV
S
D
V
S
S
L
ANLTN
I
N
W
LSAGHNQISDLT
P
L
A
N
L
T
R
I
T
QLGLNDQAWTNAPV
N
Y
K
ANVSIP
N
T
V
K
N
VTG
A
L
IA
P
A
T
ISDGGSYTEP
D
I
T
WNLPSYTN
E
V
S
Y
TFSQ
P
V
T
IGKG
T
T
TFSG
T
V
T
Q
P
L
K
A
I
F
N
V
K
F
H
VDGKET
T
K
EVEAGNLLTEPAKPVKEG
H
T
F
V
G
W
F
DAQTGGTKWNFSTDKMPTND
I
N
L
Y
A
Q
F
S
IN
S
Y
T
A
TFD----------NDGVTTSQTV
D
---
Y
QGLL--QEPTAPTKEG
Y
T
F
K
G
---
W
Y
DAKTGG---------DKWDFATSKMPA-K
N
I
T
L
Y
A
Q
Y---SAN
S
-
Y
T
A
T
F
D
VDG-KST
T
Q
AV
D
Y
Q
G
----
L
LKEPKAPTKAG
Y
T
F
K
------
G
W
YDEKTDGKKWDFATDKMPAN
D
I
T
L
Y
A
Q
FTKNPVAPPTTGGNTPPTTNNGGNTTPPSANIPGSDTSNTSTGNSASTT
S
T
M
NAYDPYNSKEASLPTTGDSD
N
A
L
Y
L
L
L
G
L
L
A
V
G
T
A
M
A
L
T
K
KARASK
4
PsiBlast_PDB
95.98
99%
-134
- C- -
2OMY
5
INLA_LISMO
A:
[1-461]
-----------------------------------
A
T
I
-
T
Q
D
T
P
I
N
Q
I
F
T
D
T
A
L
A
E
K
M
K
T
V
L
G
K
T
N
V
T
D
T
V
S
Q
T
D
L
D
Q
V
T
T
L
Q
A
D
R
L
G
I
K
S
I
D
G
V
E
Y
L
N
N
L
T
Q
I
N
F
S
N
N
Q
L
T
D
I
T
P
L
K
N
L
T
K
L
V
D
I
L
M
N
N
N
Q
I
A
D
I
T
P
--
L
A
N
L
T
N
L
T
G
L
T
L
F
N
N
Q
I
T
D
I
--
D
P
L
K
N
L
T
N
L
N
R
L
E
L
S
S
N
-
T
I
S
D
I
S
A
L
S
G
L
T
S
L
Q
Q
L
N
F
-
G
-
N
Q
V
T
D
L
K
P
L
A
N
L
T
T
L
E
R
L
D
I
S
S
N
K
V
S
D
I
--
S
V
L
A
K
L
T
N
L
E
S
L
I
A
T
N
N
Q
I
S
D
I
T
P
L
G
I
---
L
T
N
L
D
E
L
S
L
N
G
N
Q
L
K
D
I
G
T
L
A
S
L
T
N
L
T
D
L
D
L
A
N
N
Q
I
S
N
L
A
P
L
S
G
L
T
K
L
T
E
L
K
L
G
A
N
Q
I
S
N
I
S
P
L
A
G
L
T
A
L
T
N
L
E
L
N
E
N
Q
L
--
E
D
I
S
P
I
S
N
L
K
N
L
T
Y
L
T
L
Y
F
N
N
I
S
D
I
S
P
V
S
S
L
T
K
L
Q
R
L
F
F
Y
N
N
K
V
S
D
V
S
S
L
A
N
L
T
N
I
N
W
L
S
A
G
H
N
Q
I
S
D
L
T
P
L
A
N
L
T
R
I
T
Q
L
G
L
N
D
Q
A
W
T
N
A
P
V
N
Y
K
A
N
V
S
I
P
N
T
V
K
N
V
T
G
A
L
I
A
P
A
T
I
S
D
G
G
S
Y
T
E
P
D
I
T
W
N
L
P
S
Y
T
N
E
V
S
Y
T
F
S
Q
P
V
T
I
G
K
G
T
T
T
F
S
G
T
V
T
Q
P
L
K
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
94.79
99%
-134
- C- -
2OMV
3
INLA_LISMO
A:
[1-461]
-----------------------------------
A
T
I
-
T
Q
D
T
P
I
N
Q
I
F
T
D
T
A
L
A
E
K
M
K
T
V
L
G
K
T
N
V
T
D
T
V
S
Q
T
D
L
D
Q
V
T
T
L
Q
A
D
R
L
G
I
K
S
I
D
G
V
E
Y
L
N
N
L
T
Q
I
N
F
S
N
N
Q
L
T
D
I
T
P
L
K
N
L
T
K
L
V
D
I
L
M
N
N
N
Q
I
A
D
I
T
P
--
L
A
N
L
T
N
L
T
G
L
T
L
F
N
N
Q
I
T
D
I
--
D
P
L
K
N
L
T
N
L
N
R
L
E
L
S
S
N
-
T
I
S
D
I
S
A
L
S
G
L
T
S
L
Q
Q
L
N
F
-
G
-
N
Q
V
T
D
L
K
P
L
A
N
L
T
T
L
E
R
L
D
I
S
S
N
K
V
S
D
I
--
S
V
L
A
K
L
T
N
L
E
S
L
I
A
T
N
N
Q
I
S
D
I
T
P
L
G
I
---
L
T
N
L
D
E
L
S
L
N
G
N
Q
L
K
D
I
G
T
L
A
S
L
T
N
L
T
D
L
D
L
A
N
N
Q
I
S
N
L
A
P
L
S
G
L
T
K
L
T
E
L
K
L
G
A
N
Q
I
S
N
I
S
P
L
A
G
L
T
A
L
T
N
L
E
L
N
E
N
Q
L
--
E
D
I
S
P
I
S
N
L
K
N
L
T
Y
L
T
L
Y
F
N
N
I
S
D
I
S
P
V
S
S
L
T
K
L
Q
R
L
F
F
S
N
N
K
V
S
D
V
S
S
L
A
N
L
T
N
I
N
W
L
S
A
G
H
N
Q
I
S
D
L
T
P
L
A
N
L
T
R
I
T
Q
L
G
L
N
D
Q
A
W
T
N
A
P
V
N
Y
K
A
N
V
S
I
P
N
T
V
K
N
V
T
G
A
L
I
A
P
A
T
I
S
D
G
G
S
Y
T
E
P
D
I
T
W
N
L
P
S
Y
T
N
E
V
S
Y
T
F
S
Q
P
V
T
I
G
K
G
T
T
T
F
S
G
T
V
T
Q
P
L
K
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
94.59
99%
-134
- C- -
1O6S
4
INLA_LISMO
A:
[6-466]
-----------------------------------
A
T
I
-
T
Q
D
T
P
I
N
Q
I
F
T
D
T
A
L
A
E
K
M
K
T
V
L
G
K
T
N
V
T
D
T
V
S
Q
T
D
L
D
Q
V
T
T
L
Q
A
D
R
L
G
I
K
S
I
D
G
V
E
Y
L
N
N
L
T
Q
I
N
F
S
N
N
Q
L
T
D
I
T
P
L
K
N
L
T
K
L
V
D
I
L
M
N
N
N
Q
I
A
D
I
T
P
--
L
A
N
L
T
N
L
T
G
L
T
L
F
N
N
Q
I
T
D
I
--
D
P
L
K
N
L
T
N
L
N
R
L
E
L
S
S
N
-
T
I
S
D
I
S
A
L
S
G
L
T
S
L
Q
Q
L
S
F
-
G
-
N
Q
V
T
D
L
K
P
L
A
N
L
T
T
L
E
R
L
D
I
S
S
N
K
V
S
D
I
--
S
V
L
A
K
L
T
N
L
E
S
L
I
A
T
N
N
Q
I
S
D
I
T
P
L
G
I
---
L
T
N
L
D
E
L
S
L
N
G
N
Q
L
K
D
I
G
T
L
A
S
L
T
N
L
T
D
L
D
L
A
N
N
Q
I
S
N
L
A
P
L
S
G
L
T
K
L
T
E
L
K
L
G
A
N
Q
I
S
N
I
S
P
L
A
G
L
T
A
L
T
N
L
E
L
N
E
N
Q
L
--
E
D
I
S
P
I
S
N
L
K
N
L
T
Y
L
T
L
Y
F
N
N
I
S
D
I
S
P
V
S
S
L
T
K
L
Q
R
L
F
F
Y
N
N
K
V
S
D
V
S
S
L
A
N
L
T
N
I
N
W
L
S
A
G
H
N
Q
I
S
D
L
T
P
L
A
N
L
T
R
I
T
Q
L
G
L
N
D
Q
A
W
T
N
A
P
V
N
Y
K
A
N
V
S
I
P
N
T
V
K
N
V
T
G
A
L
I
A
P
A
T
I
S
D
G
G
S
Y
T
E
P
D
I
T
W
N
L
P
S
Y
T
N
E
V
S
Y
T
F
S
Q
P
V
T
I
G
K
G
T
T
T
F
S
G
T
V
T
Q
P
L
K
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
94.41
99%
-132
- C- -
1O6V
1
INLA_LISMO
B:
[6-466]
-----------------------------------
A
T
I
-
T
Q
D
T
P
I
N
Q
I
F
T
D
T
A
L
A
E
K
M
K
T
V
L
G
K
T
N
V
T
D
T
V
S
Q
T
D
L
D
Q
V
T
T
L
Q
A
D
R
L
G
I
K
S
I
D
G
V
E
Y
L
N
N
L
T
Q
I
N
F
S
N
N
Q
L
T
D
I
T
P
L
K
N
L
T
K
L
V
D
I
L
M
N
N
N
Q
I
A
D
I
T
P
--
L
A
N
L
T
N
L
T
G
L
T
L
F
N
N
Q
I
T
D
I
--
D
P
L
K
N
L
T
N
L
N
R
L
E
L
S
S
N
-
T
I
S
D
I
S
A
L
S
G
L
T
S
L
Q
Q
L
S
F
-
G
-
N
Q
V
T
D
L
K
P
L
A
N
L
T
T
L
E
R
L
D
I
S
S
N
K
V
S
D
I
--
S
V
L
A
K
L
T
N
L
E
S
L
I
A
T
N
N
Q
I
S
D
I
T
P
L
G
I
---
L
T
N
L
D
E
L
S
L
N
G
N
Q
L
K
D
I
G
T
L
A
S
L
T
N
L
T
D
L
D
L
A
N
N
Q
I
S
N
L
A
P
L
S
G
L
T
K
L
T
E
L
K
L
G
A
N
Q
I
S
N
I
S
P
L
A
G
L
T
A
L
T
N
L
E
L
N
E
N
Q
L
--
E
D
I
S
P
I
S
N
L
K
N
L
T
Y
L
T
L
Y
F
N
N
I
S
D
I
S
P
V
S
S
L
T
K
L
Q
R
L
F
F
Y
N
N
K
V
S
D
V
S
S
L
A
N
L
T
N
I
N
W
L
S
A
G
H
N
Q
I
S
D
L
T
P
L
A
N
L
T
R
I
T
Q
L
G
L
N
D
Q
A
W
T
N
A
P
V
N
Y
K
A
N
V
S
I
P
N
T
V
K
N
V
T
G
A
L
I
A
P
A
T
I
S
D
G
G
S
Y
T
E
P
D
I
T
W
N
L
P
S
Y
T
N
E
V
S
Y
T
F
S
Q
P
V
T
I
G
K
G
T
T
T
F
S
G
T
V
T
Q
P
L
K
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
94.22
99%
-132
- C- -
1O6T
11
INLA_LISMO
A:
[5-466]
----------------------------------
S
A
T
I
-
T
Q
D
T
P
I
N
Q
I
F
T
D
T
A
L
A
E
K
M
K
T
V
L
G
K
T
N
V
T
D
T
V
S
Q
T
D
L
D
Q
V
T
T
L
Q
A
D
R
L
G
I
K
S
I
D
G
V
E
Y
L
N
N
L
T
Q
I
N
F
S
N
N
Q
L
T
D
I
T
P
L
K
N
L
T
K
L
V
D
I
L
M
N
N
N
Q
I
A
D
I
T
P
--
L
A
N
L
T
N
L
T
G
L
T
L
F
N
N
Q
I
T
D
I
--
D
P
L
K
N
L
T
N
L
N
R
L
E
L
S
S
N
-
T
I
S
D
I
S
A
L
S
G
L
T
S
L
Q
Q
L
S
F
-
G
-
N
Q
V
T
D
L
K
P
L
A
N
L
T
T
L
E
R
L
D
I
S
S
N
K
V
S
D
I
--
S
V
L
A
K
L
T
N
L
E
S
L
I
A
T
N
N
Q
I
S
D
I
T
P
L
G
I
---
L
T
N
L
D
E
L
S
L
N
G
N
Q
L
K
D
I
G
T
L
A
S
L
T
N
L
T
D
L
D
L
A
N
N
Q
I
S
N
L
A
P
L
S
G
L
T
K
L
T
E
L
K
L
G
A
N
Q
I
S
N
I
S
P
L
A
G
L
T
A
L
T
N
L
E
L
N
E
N
Q
L
--
E
D
I
S
P
I
S
N
L
K
N
L
T
Y
L
T
L
Y
F
N
N
I
S
D
I
S
P
V
S
S
L
T
K
L
Q
R
L
F
F
Y
N
N
K
V
S
D
V
S
S
L
A
N
L
T
N
I
N
W
L
S
A
G
H
N
Q
I
S
D
L
T
P
L
A
N
L
T
R
I
T
Q
L
G
L
N
D
Q
A
W
T
N
A
P
V
N
Y
K
A
N
V
S
I
P
N
T
V
K
N
V
T
G
A
L
I
A
P
A
T
I
S
D
G
G
S
Y
T
E
P
D
I
T
W
N
L
P
S
Y
T
N
E
V
S
Y
T
F
S
Q
P
V
T
I
G
K
G
T
T
T
F
S
G
T
V
T
Q
P
L
K
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
94.13
99%
-123
- C4 -
2OMX
2
INLA_LISMO
A:
[1-462]
-----------------------------------
A
T
I
-
T
Q
D
T
P
I
N
Q
I
F
T
D
T
A
L
A
E
K
M
K
T
V
L
G
K
T
N
V
T
D
T
V
S
Q
T
D
L
D
Q
V
T
T
L
Q
A
D
R
L
G
I
K
S
I
D
G
V
E
Y
L
N
N
L
T
Q
I
N
F
S
N
N
Q
L
T
D
I
T
P
L
K
N
L
T
K
L
V
D
I
L
M
N
N
N
Q
I
A
D
I
T
P
--
L
A
N
L
T
N
L
T
G
L
T
L
F
N
N
Q
I
T
D
I
--
D
P
L
K
N
L
T
N
L
N
R
L
E
L
S
S
N
-
T
I
S
D
I
S
A
L
S
G
L
T
S
L
Q
Q
L
N
F
-
S
S
N
Q
V
T
D
L
K
P
L
A
N
L
T
T
L
E
R
L
D
I
S
S
N
K
V
S
D
I
--
S
V
L
A
K
L
T
N
L
E
S
L
I
A
T
N
N
Q
I
S
D
I
T
P
L
G
I
---
L
T
N
L
D
E
L
S
L
N
G
N
Q
L
K
D
I
G
T
L
A
S
L
T
N
L
T
D
L
D
L
A
N
N
Q
I
S
N
L
A
P
L
S
G
L
T
K
L
T
E
L
K
L
G
A
N
Q
I
S
N
I
S
P
L
A
G
L
T
A
L
T
N
L
E
L
N
E
N
Q
L
--
E
D
I
S
P
I
S
N
L
K
N
L
T
Y
L
T
L
Y
F
N
N
I
S
D
I
S
P
V
S
S
L
T
K
L
Q
R
L
F
F
Y
N
N
K
V
S
D
V
S
S
L
A
N
L
T
N
I
N
W
L
S
A
G
H
N
Q
I
S
D
L
T
P
L
A
N
L
T
R
I
T
Q
L
G
L
N
D
Q
A
W
T
N
A
P
V
N
Y
K
A
N
V
S
I
P
N
T
V
K
N
V
T
G
A
L
I
A
P
A
T
I
S
D
G
G
S
Y
T
E
P
D
I
T
W
N
L
P
S
Y
T
N
E
V
S
Y
T
F
S
Q
P
V
T
I
G
K
G
T
T
T
F
S
G
T
V
T
Q
P
L
K
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
93.93
99%
-122
- C4 -
2OMZ
-
INLA_LISMO
A:
[35-496]
----------------------------------
S
A
T
I
-
T
Q
D
T
P
I
N
Q
I
F
T
D
T
A
L
A
E
K
M
K
T
V
L
G
K
T
N
V
T
D
T
V
S
Q
T
D
L
D
Q
V
T
T
L
Q
A
D
R
L
G
I
K
S
I
D
G
V
E
Y
L
N
N
L
T
Q
I
N
F
S
N
N
Q
L
T
D
I
T
P
L
K
N
L
T
K
L
V
D
I
L
M
N
N
N
Q
I
A
D
I
T
P
--
L
A
N
L
T
N
L
T
G
L
T
L
F
N
N
Q
I
T
D
I
--
D
P
L
K
N
L
T
N
L
N
R
L
E
L
S
S
N
-
T
I
S
D
I
S
A
L
S
G
L
T
S
L
Q
Q
L
S
F
-
G
-
N
Q
V
T
D
L
K
P
L
A
N
L
T
T
L
E
R
L
D
I
S
S
N
K
V
S
D
I
--
S
V
L
A
K
L
T
N
L
E
S
L
I
A
T
N
N
Q
I
S
D
I
T
P
L
G
I
---
L
T
N
L
D
E
L
S
L
N
G
N
Q
L
K
D
I
G
T
L
A
S
L
T
N
L
T
D
L
D
L
A
N
N
Q
I
S
N
L
A
P
L
S
G
L
T
K
L
T
E
L
K
L
G
A
N
Q
I
S
N
I
S
P
L
A
G
L
T
A
L
T
N
L
E
L
N
E
N
Q
L
--
E
D
I
S
P
I
S
N
L
K
N
L
T
Y
L
T
L
Y
F
N
N
I
S
D
I
S
P
V
S
S
L
T
K
L
Q
R
L
F
F
A
N
N
K
V
S
D
V
S
S
L
A
N
L
T
N
I
N
W
L
S
A
G
H
N
Q
I
S
D
L
T
P
L
A
N
L
T
R
I
T
Q
L
G
L
N
D
Q
A
W
T
N
A
P
V
N
Y
K
A
N
V
S
I
P
N
T
V
K
N
V
T
G
A
L
I
A
P
A
T
I
S
D
G
G
S
Y
T
E
P
D
I
T
W
N
L
P
S
Y
T
N
E
V
S
Y
T
F
S
Q
P
V
T
I
G
K
G
T
T
T
F
S
G
T
V
T
Q
P
L
K
G
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
93.43
99%
-133
- C- -
1O6V
1
INLA_LISMO
A:
[5-466]
----------------------------------
S
A
T
I
-
T
Q
D
T
P
I
N
Q
I
F
T
D
T
A
L
A
E
K
M
K
T
V
L
G
K
T
N
V
T
D
T
V
S
Q
T
D
L
D
Q
V
T
T
L
Q
A
D
R
L
G
I
K
S
I
D
G
V
E
Y
L
N
N
L
T
Q
I
N
F
S
N
N
Q
L
T
D
I
T
P
L
K
N
L
T
K
L
V
D
I
L
M
N
N
N
Q
I
A
D
I
T
P
--
L
A
N
L
T
N
L
T
G
L
T
L
F
N
N
Q
I
T
D
I
--
D
P
L
K
N
L
T
N
L
N
R
L
E
L
S
S
N
-
T
I
S
D
I
S
A
L
S
G
L
T
S
L
Q
Q
L
S
F
-
G
-
N
Q
V
T
D
L
K
P
L
A
N
L
T
T
L
E
R
L
D
I
S
S
N
K
V
S
D
I
--
S
V
L
A
K
L
T
N
L
E
S
L
I
A
T
N
N
Q
I
S
D
I
T
P
L
G
I
---
L
T
N
L
D
E
L
S
L
N
G
N
Q
L
K
D
I
G
T
L
A
S
L
T
N
L
T
D
L
D
L
A
N
N
Q
I
S
N
L
A
P
L
S
G
L
T
K
L
T
E
L
K
L
G
A
N
Q
I
S
N
I
S
P
L
A
G
L
T
A
L
T
N
L
E
L
N
E
N
Q
L
--
E
D
I
S
P
I
S
N
L
K
N
L
T
Y
L
T
L
Y
F
N
N
I
S
D
I
S
P
V
S
S
L
T
K
L
Q
R
L
F
F
Y
N
N
K
V
S
D
V
S
S
L
A
N
L
T
N
I
N
W
L
S
A
G
H
N
Q
I
S
D
L
T
P
L
A
N
L
T
R
I
T
Q
L
G
L
N
D
Q
A
W
T
N
A
P
V
N
Y
K
A
N
V
S
I
P
N
T
V
K
N
V
T
G
A
L
I
A
P
A
T
I
S
D
G
G
S
Y
T
E
P
D
I
T
W
N
L
P
S
Y
T
N
E
V
S
Y
T
F
S
Q
P
V
T
I
G
K
G
T
T
T
F
S
G
T
V
T
Q
P
L
K
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
93.41
99%
-124
- C4 -
2OMU
2
INLA_LISMO
A:
[1-462]
-----------------------------------
A
T
I
-
T
Q
D
T
P
I
N
Q
I
F
T
D
T
A
L
A
E
K
M
K
T
V
L
G
K
T
N
V
T
D
T
V
S
Q
T
D
L
D
Q
V
T
T
L
Q
A
D
R
L
G
I
K
S
I
D
G
V
E
Y
L
N
N
L
T
Q
I
N
F
S
N
N
Q
L
T
D
I
T
P
L
K
N
L
T
K
L
V
D
I
L
M
N
N
N
Q
I
A
D
I
T
P
--
L
A
N
L
T
N
L
T
G
L
T
L
F
N
N
Q
I
T
D
I
--
D
P
L
K
N
L
T
N
L
N
R
L
E
L
S
S
N
-
T
I
S
D
I
S
A
L
S
G
L
T
S
L
Q
Q
L
S
F
-
S
S
N
Q
V
T
D
L
K
P
L
A
N
L
T
T
L
E
R
L
D
I
S
S
N
K
V
S
D
I
--
S
V
L
A
K
L
T
N
L
E
S
L
I
A
T
N
N
Q
I
S
D
I
T
P
L
G
I
---
L
T
N
L
D
E
L
S
L
N
G
N
Q
L
K
D
I
G
T
L
A
S
L
T
N
L
T
D
L
D
L
A
N
N
Q
I
S
N
L
A
P
L
S
G
L
T
K
L
T
E
L
K
L
G
A
N
Q
I
S
N
I
S
P
L
A
G
L
T
A
L
T
N
L
E
L
N
E
N
Q
L
--
E
D
I
S
P
I
S
N
L
K
N
L
T
Y
L
T
L
Y
F
N
N
I
S
D
I
S
P
V
S
S
L
T
K
L
Q
R
L
F
F
S
N
N
K
V
S
D
V
S
S
L
A
N
L
T
N
I
N
W
L
S
A
G
H
N
Q
I
S
D
L
T
P
L
A
N
L
T
R
I
T
Q
L
G
L
N
D
Q
A
W
T
N
A
P
V
N
Y
K
A
N
V
S
I
P
N
T
V
K
N
V
T
G
A
L
I
A
P
A
T
I
S
D
G
G
S
Y
T
E
P
D
I
T
W
N
L
P
S
Y
T
N
E
V
S
Y
T
F
S
Q
P
V
T
I
G
K
G
T
T
T
F
S
G
T
V
T
Q
P
L
K
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
93.33
99%
-121
- C4 -
2OMW
5
INLA_LISMO
A:
[1-461]
-----------------------------------
A
T
I
-
T
Q
D
T
P
I
N
Q
I
F
T
D
T
A
L
A
E
K
M
K
T
V
L
G
K
T
N
V
T
D
T
V
S
Q
T
D
L
D
Q
V
T
T
L
Q
A
D
R
L
G
I
K
S
I
D
G
V
E
Y
L
N
N
L
T
Q
I
N
F
S
N
N
Q
L
T
D
I
T
P
L
K
N
L
T
K
L
V
D
I
L
M
N
N
N
Q
I
A
D
I
T
P
--
L
A
N
L
T
N
L
T
G
L
T
L
F
N
N
Q
I
T
D
I
--
D
P
L
K
N
L
T
N
L
N
R
L
E
L
S
S
N
-
T
I
S
D
I
S
A
L
S
G
L
T
S
L
Q
Q
L
N
F
-
G
-
N
Q
V
T
D
L
K
P
L
A
N
L
T
T
L
E
R
L
D
I
S
S
N
K
V
S
D
I
--
S
V
L
A
K
L
T
N
L
E
S
L
I
A
T
N
N
Q
I
S
D
I
T
P
L
G
I
---
L
T
N
L
D
E
L
S
L
N
G
N
Q
L
K
D
I
G
T
L
A
S
L
T
N
L
T
D
L
D
L
A
N
N
Q
I
S
N
L
A
P
L
S
G
L
T
K
L
T
E
L
K
L
G
A
N
Q
I
S
N
I
S
P
L
A
G
L
T
A
L
T
N
L
E
L
N
E
N
Q
L
--
E
D
I
S
P
I
S
N
L
K
N
L
T
Y
L
T
L
Y
F
N
N
I
S
D
I
S
P
V
S
S
L
T
K
L
Q
R
L
F
F
S
N
N
K
V
S
D
V
S
S
L
A
N
L
T
N
I
N
W
L
S
A
G
H
N
Q
I
S
D
L
T
P
L
A
N
L
T
R
I
T
Q
L
G
L
N
D
Q
A
W
T
N
A
P
V
N
Y
K
A
N
V
S
I
P
N
T
V
K
N
V
T
G
A
L
I
A
P
A
T
I
S
D
G
G
S
Y
T
E
P
D
I
T
W
N
L
P
S
Y
T
N
E
V
S
Y
T
F
S
Q
P
V
T
I
G
K
G
T
T
T
F
S
G
T
V
T
Q
P
L
K
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
82
HHSearch
93.09
100%
-123
- C4 -
1O6V
1
INLA_LISMO
A:
[6-465]
-----------------------------------
A
T
I
-
T
Q
D
T
P
I
N
Q
I
F
T
D
T
A
L
A
E
K
M
K
T
V
L
G
K
T
N
V
T
D
T
V
S
Q
T
D
L
D
Q
V
T
T
L
Q
A
D
R
L
G
I
K
S
I
D
G
V
E
Y
L
N
N
L
T
Q
I
N
F
S
N
N
Q
L
T
D
I
T
P
L
K
N
L
T
K
L
V
D
I
L
M
N
N
N
Q
I
A
D
I
T
P
--
L
A
N
L
T
N
L
T
G
L
T
L
F
N
N
Q
I
T
D
I
--
D
P
L
K
N
L
T
N
L
N
R
L
E
L
S
S
N
-
T
I
S
D
I
S
A
L
S
G
L
T
S
L
Q
Q
L
S
F
-
G
-
N
Q
V
T
D
L
K
P
L
A
N
L
T
T
L
E
R
L
D
I
S
S
N
K
V
S
D
I
--
S
V
L
A
K
L
T
N
L
E
S
L
I
A
T
N
N
Q
I
S
D
I
T
P
L
G
I
---
L
T
N
L
D
E
L
S
L
N
G
N
Q
L
K
D
I
G
T
L
A
S
L
T
N
L
T
D
L
D
L
A
N
N
Q
I
S
N
L
A
P
L
S
G
L
T
K
L
T
E
L
K
L
G
A
N
Q
I
S
N
I
S
P
L
A
G
L
T
A
L
T
N
L
E
L
N
E
N
Q
L
--
E
D
I
S
P
I
S
N
L
K
N
L
T
Y
L
T
L
Y
F
N
N
I
S
D
I
S
P
V
S
S
L
T
K
L
Q
R
L
F
F
Y
N
N
K
V
S
D
V
S
S
L
A
N
L
T
N
I
N
W
L
S
A
G
H
N
Q
I
S
D
L
T
P
L
A
N
L
T
R
I
T
Q
L
G
L
N
D
Q
A
W
T
N
A
P
V
N
Y
K
A
N
V
S
I
P
N
T
V
K
N
V
T
G
A
L
I
A
P
A
T
I
S
D
G
G
S
Y
T
E
P
D
I
T
W
N
L
P
S
Y
T
N
E
V
S
Y
T
F
S
Q
P
V
T
I
G
K
G
T
T
T
F
S
G
T
V
T
Q
P
L
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
93.08
99%
-129
- C- -
2OMT
2
INLA_LISMO
A:
[1-462]
-----------------------------------
A
T
I
-
T
Q
D
T
P
I
N
Q
I
F
T
D
T
A
L
A
E
K
M
K
T
V
L
G
K
T
N
V
T
D
T
V
S
Q
T
D
L
D
Q
V
T
T
L
Q
A
D
R
L
G
I
K
S
I
D
G
V
E
Y
L
N
N
L
T
Q
I
N
F
S
N
N
Q
L
T
D
I
T
P
L
K
N
L
T
K
L
V
D
I
L
M
N
N
N
Q
I
A
D
I
T
P
--
L
A
N
L
T
N
L
T
G
L
T
L
F
N
N
Q
I
T
D
I
--
D
P
L
K
N
L
T
N
L
N
R
L
E
L
S
S
N
-
T
I
S
D
I
S
A
L
S
G
L
T
S
L
Q
Q
L
S
F
-
S
S
N
Q
V
T
D
L
K
P
L
A
N
L
T
T
L
E
R
L
D
I
S
S
N
K
V
S
D
I
--
S
V
L
A
K
L
T
N
L
E
S
L
I
A
T
N
N
Q
I
S
D
I
T
P
L
G
I
---
L
T
N
L
D
E
L
S
L
N
G
N
Q
L
K
D
I
G
T
L
A
S
L
T
N
L
T
D
L
D
L
A
N
N
Q
I
S
N
L
A
P
L
S
G
L
T
K
L
T
E
L
K
L
G
A
N
Q
I
S
N
I
S
P
L
A
G
L
T
A
L
T
N
L
E
L
N
E
N
Q
L
--
E
D
I
S
P
I
S
N
L
K
N
L
T
Y
L
T
L
Y
F
N
N
I
S
D
I
S
P
V
S
S
L
T
K
L
Q
R
L
F
F
Y
N
N
K
V
S
D
V
S
S
L
A
N
L
T
N
I
N
W
L
S
A
G
H
N
Q
I
S
D
L
T
P
L
A
N
L
T
R
I
T
Q
L
G
L
N
D
Q
A
W
T
N
A
P
V
N
Y
K
A
N
V
S
I
P
N
T
V
K
N
V
T
G
A
L
I
A
P
A
T
I
S
D
G
G
S
Y
T
E
P
D
I
T
W
N
L
P
S
Y
T
N
E
V
S
Y
T
F
S
Q
P
V
T
I
G
K
G
T
T
T
F
S
G
T
V
T
Q
P
L
K
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
86
HHSearch
77.03
42%
-126
- C4 -
1O6V
1
INLA_LISMO
A:
[36-369]
----------------------------------------------------------------------------------------
V
T
D
T
V
S
Q
T
D
L
D
Q
V
T
T
L
Q
A
D
R
L
G
I
K
S
I
D
G
V
E
Y
L
N
N
L
T
Q
I
N
F
S
N
N
Q
L
T
D
I
T
P
--
L
K
N
L
T
K
L
V
D
I
L
M
N
N
N
Q
I
A
D
I
--
T
P
L
A
N
L
T
N
L
T
G
L
T
L
F
N
N
-
Q
I
T
D
I
D
P
L
K
N
L
T
N
L
N
R
L
E
L
-
S
S
N
T
I
S
D
I
S
A
L
S
G
L
T
S
L
Q
Q
L
S
F
G
N
-
Q
V
T
D
L
--
K
P
L
A
N
L
T
T
L
E
R
L
D
I
S
S
N
K
V
S
D
I
S
V
L
A
K
---
L
T
N
L
E
S
L
I
A
T
N
N
Q
I
S
D
I
T
P
L
G
I
L
T
N
L
D
E
L
S
L
N
G
N
Q
L
K
D
I
G
T
L
A
S
L
T
N
L
T
D
L
D
L
A
N
N
Q
I
S
N
L
A
P
L
S
G
L
T
K
L
T
E
L
K
L
G
A
N
Q
I
--
S
N
I
S
P
L
A
G
L
T
A
L
T
N
L
E
L
N
E
N
Q
L
E
D
I
S
P
I
S
N
L
K
N
L
T
Y
L
T
L
Y
F
N
N
I
S
D
I
S
P
V
S
S
L
T
K
L
Q
R
L
F
F
Y
N
N
K
V
S
D
V
S
S
L
A
N
L
T
N
I
N
W
L
S
A
G
H
N
Q
I
S
D
L
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
85
HHSearch
64.62
49%
-105
- C4 -
1H6U
-
?
A:
[38-342]
-------------------------------------
I
-
T
Q
P
T
A
I
N
V
I
F
P
D
P
A
L
A
N
A
I
K
I
A
A
G
K
S
N
V
T
D
T
V
T
Q
A
D
L
D
G
I
T
T
L
S
A
F
G
T
G
V
T
T
I
E
G
V
Q
Y
L
N
N
L
I
G
L
E
L
K
D
N
Q
I
T
D
L
A
P
L
K
N
L
T
K
I
T
E
L
E
L
S
G
N
P
L
K
N
V
S
A
--
I
------------------------
A
G
L
Q
S
I
K
T
L
D
L
T
S
T
-
Q
I
T
D
V
T
P
-----------------------
L
A
------------------------
G
L
S
N
L
Q
V
L
Y
L
D
L
N
Q
I
T
-----------------------------------------------
N
I
S
P
L
A
----------------------
G
L
T
N
L
Q
Y
L
S
I
G
N
A
Q
V
--
S
D
L
T
P
L
A
N
L
S
K
L
T
T
L
K
A
D
D
N
K
I
S
D
I
S
----------------------
P
L
A
S
L
P
N
L
I
E
V
H
L
K
N
N
Q
I
S
D
V
S
P
L
A
N
T
S
N
L
F
I
V
T
L
T
N
Q
T
I
T
N
Q
P
V
F
Y
N
N
N
L
V
V
P
N
V
V
K
G
P
S
G
A
P
I
A
P
A
T
I
S
D
N
G
T
Y
A
S
P
N
L
T
W
N
L
T
S
F
I
N
N
V
S
Y
T
F
N
Q
S
V
T
F
K
N
T
T
V
P
F
S
G
T
V
T
Q
P
L
T
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
64.14
45%
-118
- C4 -
4FMZ
8
?
A:
[4-343]
------------------------------------
T
L
A
T
L
P
A
P
I
N
Q
I
F
P
D
A
D
L
A
E
G
I
R
A
V
L
Q
K
A
S
V
T
D
V
V
T
Q
E
E
L
E
S
I
T
K
L
V
V
A
G
E
K
V
A
S
I
Q
G
I
E
Y
L
T
N
L
E
Y
L
N
L
N
G
N
Q
I
T
D
I
S
P
L
S
N
L
V
K
L
T
N
L
Y
I
G
T
N
K
I
T
D
I
S
A
--
L
Q
N
L
T
N
L
R
E
L
Y
L
N
E
D
N
I
S
D
I
--
S
P
L
A
N
L
T
K
M
Y
S
L
N
L
G
A
N
H
N
L
S
D
L
S
P
L
S
N
M
T
G
L
N
Y
L
T
V
T
E
-
S
K
V
K
D
V
T
P
I
A
N
L
T
D
L
Y
S
L
S
L
N
Y
N
Q
I
E
D
I
--
S
P
L
A
S
L
T
S
L
H
Y
F
T
A
Y
V
N
Q
I
T
D
I
T
P
V
A
N
---
M
T
R
L
N
S
L
K
I
G
N
N
K
I
T
D
L
S
P
L
A
N
L
S
Q
L
T
W
L
E
I
G
T
N
Q
I
S
D
I
N
A
V
K
D
L
T
K
L
K
M
L
N
V
G
S
N
Q
I
S
D
I
S
V
L
N
N
L
S
Q
L
N
S
L
F
L
N
N
N
Q
L
GN
E
D
M
E
V
I
G
G
L
T
N
L
T
T
L
F
L
S
Q
N
H
I
T
D
I
R
P
L
A
S
L
S
K
M
D
S
A
D
F
A
N
Q
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
61.10
40%
-98
- C4 -
2WQU
5
INLB_LISMO
E:
[28-288]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
L
K
K
K
S
V
T
D
A
--
V
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
I
Q
Y
---
L
P
N
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
L
A
N
L
K
N
L
G
W
L
F
L
D
E
N
K
V
K
D
L
S
S
L
K
D
L
K
K
L
K
S
L
S
L
E
H
N
G
I
S
D
I
N
G
L
V
H
L
P
Q
L
E
S
L
Y
L
G
N
N
K
I
--
T
D
I
T
V
L
S
R
L
T
K
L
D
T
L
S
L
E
D
N
Q
I
S
D
I
V
P
L
A
G
L
T
K
L
Q
N
L
Y
L
S
K
N
H
I
S
D
L
R
A
L
A
G
L
K
N
L
D
V
L
E
----------------------
L
F
S
Q
E
C
L
N
K
P
I
N
H
Q
S
N
L
V
V
P
N
T
V
K
N
T
D
G
S
L
V
T
P
E
I
I
S
D
D
G
D
Y
E
K
P
N
V
K
W
H
L
P
E
F
T
N
E
V
S
F
I
F
Y
Q
P
V
T
I
G
K
A
K
A
R
F
H
G
R
V
T
Q
P
L
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
61.03
41%
-104
- C4 -
4AW4
9
INLB_LISMO
B:
[34-310]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
D
A
V
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
--
Q
G
I
Q
Y
L
P
N
L
T
S
L
N
L
S
N
N
Q
I
T
D
I
S
P
I
Q
Y
---
L
P
N
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
L
A
N
L
K
N
L
G
W
L
F
L
D
E
N
K
V
K
D
L
S
S
L
K
D
L
K
K
L
K
S
L
S
L
E
H
N
G
I
S
D
I
N
G
L
V
H
L
P
Q
L
E
S
L
Y
L
G
N
N
K
I
--
T
D
I
T
V
L
S
R
L
T
K
L
D
T
L
S
L
E
D
N
Q
I
S
D
I
V
P
L
A
G
L
T
K
L
Q
N
L
Y
L
S
K
N
H
I
S
D
L
R
A
L
A
G
L
K
N
L
D
V
L
E
----------------------
L
F
S
Q
E
C
L
N
K
P
I
N
H
Q
S
N
L
V
V
P
N
T
V
K
N
T
D
G
S
L
V
T
P
E
I
I
S
D
D
G
D
Y
E
K
P
N
V
K
W
H
L
P
E
F
T
N
E
V
S
F
I
F
Y
Q
P
V
T
I
G
K
A
K
A
R
F
H
G
R
V
T
Q
P
L
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
60.60
41%
-101
- C4 -
4AW4
6
INLB_LISMO
C:
[34-310]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
T
D
A
V
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
--
Q
G
I
Q
Y
L
P
N
L
T
S
L
N
L
S
N
N
Q
I
T
D
I
S
P
I
Q
Y
---
L
P
N
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
L
A
N
L
K
N
L
G
W
L
F
L
D
E
N
K
V
K
D
L
S
S
L
K
D
L
K
K
L
K
S
L
S
L
E
H
N
G
I
S
D
I
N
G
L
V
H
L
P
Q
L
E
S
L
Y
L
G
N
N
K
I
--
T
D
I
T
V
L
S
R
L
T
K
L
D
T
L
S
L
E
D
N
Q
I
S
D
I
V
P
L
A
G
L
T
K
L
Q
N
L
Y
L
S
K
N
H
I
S
D
L
R
A
L
A
G
L
K
N
L
D
V
L
E
----------------------
L
F
S
Q
E
C
L
N
K
P
I
N
H
Q
S
N
L
V
V
P
N
T
V
K
N
T
D
G
S
L
V
T
P
E
I
I
S
D
D
G
D
Y
E
K
P
N
V
K
W
H
L
P
E
F
T
N
E
V
S
F
I
F
Y
Q
P
V
T
I
G
K
A
K
A
R
F
H
G
R
V
T
Q
P
L
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
60.32
36%
-75
- C4 -
1M9S
7
INLB_LISMO
A:
[27-510]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
L
K
K
K
S
V
T
D
A
--
V
T
Q
N
E
L
N
S
I
D
Q
I
I
A
N
N
S
D
I
K
S
V
Q
G
I
Q
Y
---
L
P
N
V
T
K
L
F
L
N
G
N
K
L
T
D
I
K
P
L
T
N
L
K
N
L
G
W
L
F
L
D
E
N
K
I
K
D
L
S
S
L
K
D
L
K
K
L
K
S
L
S
L
E
H
N
G
I
S
D
I
N
G
L
V
H
L
P
Q
L
E
S
L
Y
L
G
N
N
K
I
--
T
D
I
T
V
L
S
R
L
T
K
L
D
T
L
S
L
E
D
N
Q
I
S
D
I
V
P
L
A
G
L
T
K
L
Q
N
L
Y
L
S
K
N
H
I
S
D
L
R
A
L
A
G
L
K
N
L
D
V
L
E
----------------------
L
F
S
Q
E
C
L
N
K
P
I
N
H
Q
S
N
L
V
V
P
N
T
V
K
N
T
D
G
S
L
V
T
P
E
I
I
S
D
D
G
D
Y
E
K
P
N
V
K
W
H
L
P
E
F
T
N
E
V
S
F
I
F
Y
Q
P
V
T
I
G
K
A
K
A
R
F
H
G
R
V
T
Q
P
L
-----------------------------------------------------------------------
E
T
T
E
K
T
V
N
L
T
R
Y
V
KYIRG
N
A
G
I
Y
K
L
P
R
E
D
NSL
K
Q
G
T
L
AS
H
R
C
K
A
L
T
V
D
R
E
A
R
N
G
G
K
L
W
Y
R
L
K
N
I
G
W
T
K
AENLSL
D
R
Y
D
----
K
M
E
Y
D
K
G
V
T
A
Y
A
R
V
RNA
S
G
N
S
V
W
T
K
P
Y
N
T
A
G
A
K
H
V
N
K
L
S
V
Y
Q
G
K
N
M
R
I
L
R
E
A
K
T
P
I
T
T
W
Y
Q
F
S
I
GG
K
V
I
G
W
V
D
T
R
-------------------------------------------------------------------------------------------------------------------------