@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0438: (2016-03-15 )
VKKLVAWFNGLSKMWKVVVIIGAVFVVIIALTTGEDEGEQTKTKKDSNKVVKTASRPKLSTKDLALIKADLAEFEARELSSEKILKDTIKEESWSDLDFANDNINQMIGTMKRYQQEILSIDAIKRSSEASADTEAFKKIFKEWSEFKIERIQVTIDLLNGKKDSEAVFKKTYPNQIIFKKVRTNKLQTALNNLKVGYELLDSQK
Atome Classification :
(20 SA)
--------------------------------------------------------------------------------------------------------------------------------------------------------.........---10---....------.....20--.------...-----....30.-.......40------.........50.---....--...60......--..70.....---------..-.80.....-...--90..---------......-100----..-------.....110-----------.......----..120...-...-----.130--.........140....--...150---..---......160.-----.------.....170.......180..--------.....190.......---200...-------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------------------------------------------------------------------------------------------------------------------------------------------------V
K
K
L
V
A
W
F
N
---
G
----
L
S
K
M
------
W
K
V
V
V
I
I
--
G
------
A
V
F
-----
V
V
I
I
A
L
T-TGEDEGEQ-------TKTKKDSN
K
V
V
K---TASR--PKLSTK
D
L
A
L
I
--
K
A
D
L
A
E
F
E
A
---------
R
E-L
S
S
E
K
I
L
K
-
D
T
I
--KEES---------WSDLDF-AND----
N
I
-------
N
Q
M
I
G
T
-------------
M
K
R
Y
Q
Q
E
----
I
L
S
I
D
A
IK-RSS-----EA----SA
D
T
E
A
F
K
K
I
F
K
E
W
S
E--
F
K
I
E
R
----
I
Q
---
V
T
I
D
LLNGKK-----
D
------
S
E
A
V
F
K
KTYPN
Q
I
I
F
K
K
V
R
T
--------
N
K
L
Q
T
A
L
N
N
L
K
V
G
Y
E
---LLDSQK-------------------------------------------
11
HHSearch
92.16
98%
-66
- C5 -
2XL4
2
LNTA_LISMO
A:
[26-172]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
--
P
K
L
S
T
K
D
L
A
L
I
--
K
A
D
L
A
E
F
E
A
---------
R
E
-
L
S
S
E
K
I
L
K
-
D
T
I
--
K
E
E
S
---------
W
S
D
L
D
F
-
A
N
D
----
N
I
-------
N
Q
M
I
G
T
-------------
M
K
R
Y
Q
Q
E
----
I
L
S
I
D
A
I
K
-
R
A
S
-----
E
A
----
S
A
D
T
E
A
F
K
K
I
F
K
E
W
S
E
--
F
K
I
E
R
----
I
Q
---
V
T
I
D
L
L
N
G
K
K
-----
D
------
S
E
A
V
F
K
K
T
Y
P
N
Q
I
I
F
K
K
V
R
T
--------
N
K
L
Q
T
A
L
N
N
L
K
V
G
Y
E
---
L
L
D
----------------------------------------------
1
PsiBlast_PDB
91.95
97%
-66
- C5 -
2XL4
2
LNTA_LISMO
A:
[26-172]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
--
P
K
L
S
T
K
D
L
A
L
I
--
K
A
D
L
A
E
F
E
A
---------
R
E
-
L
S
S
E
K
I
L
K
-
D
T
I
--
K
E
E
S
---------
W
S
D
L
D
F
-
A
N
D
----
N
I
-------
N
Q
M
I
G
T
-------------
M
K
R
Y
Q
Q
E
----
I
L
S
I
D
A
I
K
-
R
A
S
-----
E
A
----
S
A
D
T
E
A
F
K
K
I
F
K
E
W
S
E
--
F
K
I
E
R
----
I
Q
---
V
T
I
D
L
L
N
G
K
K
-----
D
------
S
E
A
V
F
K
K
T
Y
P
N
Q
I
I
F
K
K
V
R
T
--------
N
K
L
Q
T
A
L
N
N
L
K
V
G
Y
E
---
L
L
D
----------------------------------------------
2
PsiBlast_PDB
89.95
97%
-64
- C5 -
4CIH
-
LNTA_LISMO
A:
[1-146]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
R
--
P
K
L
S
T
K
D
L
A
L
I
--
K
A
D
L
A
E
F
E
A
---------
R
E
-
L
S
S
E
K
I
L
K
-
D
T
I
--
K
E
E
S
---------
W
S
D
L
D
F
-
A
N
D
----
N
I
-------
N
Q
M
I
G
T
-------------
M
K
R
Y
Q
Q
E
----
I
L
S
I
D
A
I
K
-
R
S
S
-----
E
A
----
S
A
D
T
E
A
F
K
K
I
F
K
E
W
S
E
--
F
K
I
E
R
----
I
Q
---
V
T
I
D
L
L
N
G
K
K
-----
D
------
S
E
A
V
F
K
K
T
Y
P
N
Q
I
I
F
D
D
V
R
T
--------
N
K
L
Q
T
A
L
N
N
L
K
V
G
Y
E
---
L
L
-----------------------------------------------
24
Fugue
47.14
16%
-27
- C3 -
1YT3
11
RND_ECOLI
A:
[1-375]
M
N
Y
Q
M
I
TT
D
D
A
L
A
S
L
C
E
A
V
RAFP
A
I
A
L
D
T
E
F
V
R
T
RTYYPQLG
L
I
Q
L
F
DGE
H
L
A
L
I
D
PLGITDW
S
P
L
K
A
I
L
R
DPS
I
T
K
F
L
H
AG
S
E
D
L
E
V
F
L
N
V
FGELPQP
L
I
D
T
Q
I
L
A
A
F
C
GRPMSWG
F
A
S
M
V
E
E
Y
SG
V
T
L
D
KSESRTDWLARPLT
E
R
Q
C
E
Y
A
A
A
D
V
W
Y
L
L
P
---
I
----
T
A
K
L
------
M
V
E
T
E
A
S
--
G
------
W
L
P
-----
A
A
L
D
E
C
R
-
L
M
Q
M
R
R
Q
E
-------
V
V
A
P
E
D
A
W
R
D
I
T
---
N
A
W
Q
----
L
R
T
R
Q
L
A
C
L
--
Q
L
-
L
A
D
W
R
L
---------
R
K
-
A
R
E
R
D
L
A
V
-
N
F
V
VR
E
E
H
L
---------
W
S
V
A
R
Y
-------------------
M
P
G
S
-------------
L
G
E
L
D
S
L
----
G
L
S
-------
G
S
-----
E
I
----
R
F
H
G
K
T
L
L
A
L
V
E
K
A
Q
T
--
L
P
E
D
A
----
L
P
---
Q
P
M
L
N
L
M
D
M
P
-----
G
------
Y
R
K
A
F
K
A
I
--
K
S
L
I
T
D
V
S
E
T
--------
H
K
---------
I
S
A
E
---
L
L
A
S
R
R
Q
I
N
Q
L
L
N
W
H
W
KLKPQNNLPELISG
W
R
G
E
L
M
A
E
A
L
H
N
L
L
Q
EYPQ
25
Fugue
42.78
14%
-25
* C4 *
1CR2
3
PRIM_BPT7
A:
[1-277]
------------------------------------------------------------------------------------------------------------------------------------------M
R
E
R
I
R
E
H
L
S
S
EES
V
G
L
L
F
S
G
C
T
---
G
----
I
N
D
K
TLGARG
G
E
V
I
M
V
T
--
S
G
SGMG
K
S
T
F
-----
V
R
Q
Q
A
L
Q
-
W
G
T
A
M
G
K
K
-------
V
G
L
A
M
L
E
E
S
V
E
E
---
T
A
E
D
--
L
I
G
L
H
N
R
V
R
L
R
--
Q
S
D
S
L
K
R
E
I
---------
I
E
-
N
G
K
F
D
Q
W
F
-
D
E
L
--
F
G
N
D
T--------
F
H
L
Y
D
S
-
F
E
A
----
E
T
-------
D
R
L
L
A
K
-------------
L
A
Y
M
R
S
G
LGCD
V
I
I
L
D
H
I
S
-
I
R
K
-----
M
I
----
D
N
L
M
T
K
L
K
G
F
A
K
S
T
G
V
--
V
L
V
V
I
----
C
H
---
L
K
S
G
A
L
R
Q
L
S
-----
D
------
T
I
I
A
L
E
R
N
N
L
V
L
V
R
I
L
K
C
R
F
--------
T
G
D
T
G
I
A
G
Y
M
E
Y
N
K
E
TG
W
L
E
P
S
S
Y
-------------------------------------------
29
Fugue
41.30
16%
-11
- C2 -
4LEU
-
PP266_ARATH
A:
[71-252]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
L
I
G
--
K
------
E
A
L
-----
F
V
I
L
G
L
K
-
R
L
----------------
K
E
D
D
E
K
L
D
K
---
F
I
K
T
HV
F
R
L
L
K
L
D
M
L
A
V
--
I
G
E
L
E
R
Q
E
E
---------
T
A
-
L
A
-
I
K
M
F
E
-
V
I
Q
--
K
Q
E
W
---------
Y
Q
P
D
V
F
-
M
Y
K
----
D
L
-------
I
V
S
L
A
K
-------------
S
K
R
M
D
E
A
----
M
A
L
W
E
K
M
K
-
K
E
N
-----
L
F
----
P
-
D
S
Q
T
Y
T
E
V
I
R
G
F
L
R
D
G
C
P
A
D
A
----
M
N
---
V
Y
E
D
M
L
K
S
P
D
-----
P
------
P
E
E
L
P
F
R
V
L
L
K
G
L
L
P
H
P
L
L
R
--------
N
K
V
K
K
D
F
E
E
L
F
P
E
K
H
---
A
Y
D
P
P
E
E------------------------------------------
10
PsiBlast_PDB
39.10
25%
-8
- C5 -
2GMY
-
?
A:
[92-145]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
D
A
V
T
-
K
I
A
-----
E
T
----
G
A
P
D
D
A
F
E
T
L
R
A
H
F
S
D
--
E
E
I
V
K
----
I
T
---
V
A
I
G
A
I
N
T
W
N
-----
R
------
I
A
V
G
F
R
S
Q
H
P
-------------------------------------------------------------------------------------
17
HHSearch
39.02
32%
59
- C5 -
2FCW
2
A:
[15-39]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
A
Q
S
--
A
N
L
T
D
K
E
L
E
A
F
--
R
E
E
L
K
H
F
E
A
---------
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
Fugue
39.00
10%
-4
- C4 -
4RPC
2
?
A:
[12-261]
------------------------------------------------------------------------------------------------------------------------------------------------K
L
H
R
M
G
EP
H
G
P
K
V
L
L
I
H
---
G
AGFY
W
Q
T
C
------
F
A
R
I
I
R
D
L
K
D
------
R
Y
C
-----
L
L
I
P
E
L
E
G
H
T
A
H
P
R
E
Y
M------
V
S
V
E
E
T
A
G
K
L
G
E
---
A
L
E
E
--
L
R
-
V
D
K
V
Q
A
I
Y
--
G
V
S
L
G
A
S
V
A
---------
V
E
M
A
I
R
G
E
I
K
V
M
N
L
L
--
L
D
G
G
QYEGMGEM
T
E
Q
Y
A
N
I
M
A
D
A
----
F
L
-------
N
L
L
A
G
E
H
L
-----------
P
S
P
V
K
E
N
M
---
G
F
A
A
N
N
D
V
-
E
V
L
-----
Q
P
LIYE
H
I
T
R
E
A
L
L
H
A
L
L
A
A
Y
R
--
Y
D
L
K
A
KNAR
V
D
---
A
R
V
S
V
L
I
G
G
N
-----
E
IYGAQF
T
P
L
L
A
E
I
S
R
H
P
L
D
I
Y
E
F
P
N
R
--------
G
H
A
E
V
L
S
K
E
P
E
K
I
S
R
---
L
I
R
E
I
L
N------------------------------------------
26
Fugue
38.52
13%
-21
- C4 -
2OZE
3
?
A:
[15-298]
------------------------------------------------------------------------------------------------------------------------------------ME
K
E
E
L
K
I
L
E
E
L
R
R
I
L
S
N
K
N
E
A
I
V
I
L
N
N
Y
FKG
G
----
V
G
K
S
------
K
L
S
T
M
F
A
--
Y
------
L
T
D
K
L
N
L
K
V
L
M
I
D
K
D
-
L
Q
A
T
L
T
K
D
L
A
K
T
F
KV
E
L
P
R
V
N
F
Y
E
G
L
K
N
GN
L
A
S
S
--
I
V
H
L
T
D
N
L
D
L
I
PG
T
F
D
L
M
L
L
P
K
L
T
R
SWT
F
E
N
E
S
-
R
L
L
A
T
L
L
A
-
P
L
K
--
S
D
Y
D
---------
L
I
I
I
D
T
-
V
P
T
PS
V
Y
T
N
-------
N
A
I
V
A
S
D
Y
V
M
I
P
L
Q
AEEES
T
N
N
I
Q
N
Y
----
I
S
Y
L
I
D
L
Q
-
E
Q
F
-----
N
P
----
G
L
D
M
I
G
F
--
V
P
Y
L
V
D
T
--
D
S
A
T
I
----
K
S
---
N
L
E
E
L
Y
K
Q
H
K
-----
E
------
D
N
L
V
F
Q
N
I
I
K
R
S
N
K
V
S
T
W
S
K
NGITEHKG
Y
D
K
K
V
L
S
M
Y
K
N
V
F
F
E
---
M
L
E
R
I
I
Q
L
E
N
E
KE------------------------------------
7
PsiBlast_PDB
35.04
24%
46
- C5 -
4HSG
1
A:
[39-127]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
E
E
M
L
K
-
D
K
I
--
R
T
E
S
---------
Y
R
D
F
I
Y
-
Q
N
P
----
H
I
FKD
K
V
V
L
D
V
G
C
G
T
-------------------
G
----
I
L
S
M
F
A
A
K
-
A
G
A
-----
K
K
----
V
L
G
V
D
Q
S
E
I
L
Y
Q
A
M
D
I
--
I
R
L
N
K
----
L
E
---
D
T
I
T
L
I
K
G
K
------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
34.48
24%
47
- C5 -
4RYL
-
?
A:
[39-127]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
E
E
M
L
K
-
D
K
I
--
R
T
E
S
---------
Y
R
D
F
I
Y
-
Q
N
P
----
H
I
FKD
K
V
V
L
D
V
G
C
G
T
-------------------
G
----
I
L
S
M
F
A
A
K
-
A
G
A
-----
K
K
----
V
L
G
V
D
Q
S
E
I
L
Y
Q
A
M
D
I
--
I
R
L
N
K
----
L
E
---
D
T
I
T
L
I
K
G
K
------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
34.46
24%
47
- C5 -
4QQN
4
A:
[39-126]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
E
E
M
L
K
-
D
K
I
--
R
T
E
S
---------
Y
R
D
F
I
Y
-
Q
N
P
----
H
I
FKD
K
V
V
L
D
V
G
C
G
T
-------------------
G
----
I
L
S
M
F
A
A
K
-
A
G
A
-----
K
K
----
V
L
G
V
D
Q
S
E
I
L
Y
Q
A
M
D
I
--
I
R
L
N
K
----
L
E
---
D
T
I
T
L
I
K
G
K
------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
34.35
24%
50
- C5 -
2FYT
1
A:
[39-121]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
E
E
M
L
K
-
D
K
I
--
R
T
E
S
---------
Y
R
D
F
I
Y
-
Q
N
P
----
H
I
FKD
K
V
V
L
D
V
G
C
G
T
-------------------
G
----
I
L
S
M
F
A
A
K
-
A
G
A
-----
K
K
----
V
L
G
V
D
Q
S
E
I
L
Y
Q
A
M
D
I
--
I
R
L
N
K
----
L
E
---
D
T
I
T
L
I
K
G
K
------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
34.12
24%
49
- C5 -
3SMQ
3
A:
[39-127]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
E
E
M
L
K
-
D
K
I
--
R
T
E
S
---------
Y
R
D
F
I
Y
-
Q
N
P
----
H
I
FKD
K
V
V
L
D
V
G
C
G
T
-------------------
G
----
I
L
S
M
F
A
A
K
-
A
G
A
-----
K
K
----
V
L
G
V
D
Q
S
E
I
L
Y
Q
A
M
D
I
--
I
R
L
N
K
----
L
E
---
D
T
I
T
L
I
K
G
K
------------------------------------------------------------------------------------------------------------
16
HHSearch
33.89
22%
22
* C5 *
1AX8
-
LEP_HUMAN
A:
[50-95]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
L
-------
S
K
M
D
Q
T
-------------
L
A
V
Y
Q
Q
I
----
L
T
S
M
P
S
-
R
-
N
V
I
-----
Q
I
----
S
N
D
L
E
N
L
R
D
L
L
H
V
L
A
F
--
S
K
S
--------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
31.38
21%
-16
- C5 -
1CR5
1
SEC18_YEAST
A:
[90-131]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
--
S
Y
L
G
S
----
I
D
---
I
D
I
S
F
R
A
---VFD
Q
D
E
------
L
A
K
Q
F
V
R
C
Y
E
S
Q
I
F
---------------------------------------------------------------------------------
15
HHSearch
27.35
23%
12
- C5 -
2JEK
2
?
A:
[100-144]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
D
D
L
K
L
C
S
S
M
T
L
F
A
R
A
----
T
D
A
N
Q
D
F
V
A
L
L
A
K
Y
----
Y
G
G
G
E
----
D
R
---
R
T
V
A
L
L
A
V
-------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
25.43
38%
95
* C7 *
4GAX
-
?
A:
[124-166]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
R
L
M
R
----
K
Q
GYF
V
T
C
D
V
F
N
N
H
K
-----
D
------
E
S
G
V
F
K
Q
S
L
K
N
H
V
----------------------------------------------------------------------------------
27
Fugue
24.51
19%
349
* C6 *
3GME
-
D:
[19-39]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
A
A
G
G
H
-------
T
A
T
H
H
A
S
A
A
P
A
R
---
P
Q
P
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------