@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0570: (2016-03-16 )
MKRDGHTHTEFCPHGTHDDVEEMILKAIELDFDEYSIVEHAPLSREFMNNTAGDKEAVTTASMAMSDLPYYFKKMNHIKKKYASDLLIHIGFEVDYLIGYEDFTRDFLDEYGPQTDDGVLSLHFLEGQGGFRSIDFSAEDYNEGIVQFYGGFEQAQLTYLEGVKQSIEADLGLFKPRRIGHISLCQKFQQFFGADTSNFSGEVMEEFQAILALVKKRDYELDFNTAGLFKSLCGETYPPKEIVTLARELKIPLVYGSDSHGVQDIGRGYNTYCQK
Atome Classification :
(20 SA)
.........10-..-.-....--..20.---..---------.....30-.......----------..40........50........60........70....----....80........90........100...--....110.......120.......130..-.....140.......150...---....160-.......170.......180.......190.......200.......210...---....220.......230.----....-...240.......250.......260....--...270...----------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MKRDGHTHTE--FC-P-HGT
H
--
D
D
V
E
E
---
M
I
---------
L
K
A
I
EL--DFDEY
S
I
----------
V
EHAP
L
S
R
E
F
M
NNTAGD
K
E
A
V
T
T
A
S
M
A
M
S
D
L
P
Y
Y
F
K
K
M
----
N
H
I
K
K
K
Y
AS
D
L
L
I
H
IG
F
E
V
D
Y
L
I
G
Y
E
D
F
T
R
--
D
F
L
D
EYGPQTDD
G
V
L
S
L
H
F
LEGQGG
F
R
SI-DFS
A
E
D
Y
N
E
G
I
V
Q
F
YGGF
E
Q
A
---
Q
L
T
Y
L
E
G
-
V
K
Q
S
I
E
A
D
LGLFKPRRI
G
H
I
S
L
C
Q
K
F
Q
Q
F
FGADTSNF
S
G
E
V
M
E
E
F
Q
A
I
L
A
L
V
K
---KRD
Y
E
LDF
N
T
A
G
L
F
K
S
-
L
----CGET-Y
P
P
K
E
I
V
T
L
A
R
ELK
I
P
L
V
YGSDSH
G
V
Q
D
I
G
--
R
G
Y
N
T
YCQK----------------------------------
8
HHSearch
99.83
93%
-85
- C5 -
3DCP
3
?
A:
[1-275]
M
K
R
D
G
H
T
H
T
E
--
F
C
-
P
-
H
G
T
H
--
D
D
V
E
E
---
M
V
---------
L
K
A
I
E
L
--
D
F
D
E
Y
S
I
----------
V
E
H
A
P
L
S
S
E
F
M
K
N
T
A
G
D
K
E
A
V
T
T
A
S
M
A
M
S
D
L
P
Y
Y
F
K
K
M
----
N
H
I
K
K
K
Y
A
S
D
L
L
I
H
I
G
F
E
V
D
Y
L
I
G
Y
E
D
F
T
R
--
D
F
L
N
E
Y
G
P
Q
T
D
D
G
V
L
S
L
H
F
L
E
G
Q
G
G
F
R
S
I
-
D
F
S
A
E
D
Y
N
E
G
I
V
Q
F
Y
G
G
F
E
Q
A
---
Q
L
A
Y
L
E
G
-
V
K
Q
S
I
E
A
D
L
G
L
F
K
P
R
R
M
G
H
I
S
L
C
Q
K
F
Q
Q
F
F
G
E
D
T
S
D
F
S
E
E
V
M
E
K
F
R
V
I
L
A
L
V
K
---
K
R
D
Y
E
L
D
F
N
T
A
G
L
F
K
P
-
L
----
C
G
E
T
-
Y
P
P
K
K
I
V
T
L
A
S
E
L
Q
I
P
F
V
Y
G
S
D
S
H
G
V
Q
D
I
G
--
R
G
Y
S
T
Y
C
Q
K
----------------------------------
1
PsiBlast_PDB
99.35
91%
-85
* C5 *
3DCP
3
?
A:
[2-275]
-
K
R
D
G
H
T
H
T
E
--
F
C
-
P
-
H
G
T
H
--
D
D
V
E
E
---
M
V
---------
L
K
A
I
E
L
--
D
F
D
E
Y
S
I
----------
V
E
H
A
P
L
S
S
E
F
M
K
N
T
A
G
D
K
E
A
V
T
T
A
S
M
A
M
S
D
L
P
Y
Y
F
K
K
M
----
N
H
I
K
K
K
Y
A
S
D
L
L
I
H
I
G
F
E
V
D
Y
L
I
G
Y
E
D
F
T
R
--
D
F
L
N
E
Y
G
P
Q
T
D
D
G
V
L
S
L
H
F
L
E
G
Q
G
G
F
R
S
I
-
D
F
S
A
E
D
Y
N
E
G
I
V
Q
F
Y
G
G
F
E
Q
A
---
Q
L
A
Y
L
E
G
-
V
K
Q
S
I
E
A
D
L
G
L
F
K
P
R
R
M
G
H
I
S
L
C
Q
K
F
Q
Q
F
F
G
E
D
T
S
D
F
S
E
E
V
M
E
K
F
R
V
I
L
A
L
V
K
---
K
R
D
Y
E
L
D
F
N
T
A
G
L
F
K
P
-
L
----
C
G
E
T
-
Y
P
P
K
K
I
V
T
L
A
S
E
L
Q
I
P
F
V
Y
G
S
D
S
H
G
V
Q
D
I
G
--
R
G
Y
S
T
Y
C
Q
K
----------------------------------
2
PsiBlast_PDB
69.89
27%
-78
- C5 -
2YXO
5
?
A:
[3-232]
---
D
S
H
V
H
T
P
--
L
C
-
G
-
H
-
A
E
--
G
H
P
E
A
---
Y
L
---------
E
E
A
R
A
K
--
G
L
K
G
V
V
F
----------
T
D
H
S
P
M
P
P
W
Y
------
D
P
E
S
----
R
M
R
L
E
A
L
P
F
Y
L
L
A
L
----
E
R
V
R
E
R
-
A
Q
D
L
Y
V
G
I
G
L
E
A
D
F
H
P
G
T
E
G
F
L
A
--
Q
L
L
R
R
Y
--
P
F
D
Y
V
I
G
S
V
H
Y
L
----
G
A
W
P
L
-
D
H
P
--
D
H
Q
E
E
Y
A
--
W
R
D
L
K
E
V
---
F
R
A
Y
F
Q
E
-
V
E
K
A
--
A
R
S
G
L
F
H
--
A
I
G
H
L
D
L
P
K
K
F
G
H
R
L
P
E
E
A
------
L
L
E
L
A
E
P
A
L
R
A
V
A
---
E
A
G
L
F
L
D
V
N
T
A
G
L
R
R
P
------
A
K
E
V
-
Y
P
A
P
A
L
L
R
R
A
R
E
L
G
I
G
L
V
L
G
S
D
A
H
R
P
E
E
V
G
---------------------------------------------
4
PsiBlast_PDB
69.81
27%
-78
- C5 -
2Z4G
4
?
A:
[3-232]
---
D
S
H
V
H
T
P
--
L
C
-
G
-
H
-
A
E
--
G
H
P
E
A
---
Y
L
---------
E
E
A
R
A
K
--
G
L
K
G
V
V
F
----------
T
D
H
S
P
M
P
P
W
Y
------
D
P
E
S
----
R
M
R
L
E
A
L
P
F
Y
L
L
A
L
----
E
R
V
R
E
R
-
A
Q
D
L
Y
V
G
I
G
L
E
A
D
F
H
P
G
T
E
G
F
L
A
--
Q
L
L
R
R
Y
--
P
F
D
Y
V
I
G
S
V
H
Y
L
----
G
A
W
P
L
-
D
H
P
--
D
H
Q
E
E
Y
A
--
W
R
D
L
K
E
V
---
F
R
A
Y
F
Q
E
-
V
E
K
A
--
A
R
S
G
L
F
H
--
A
I
G
H
L
D
L
P
K
K
F
G
H
R
L
P
E
E
A
------
L
L
E
L
A
E
P
A
L
R
A
V
A
---
E
A
G
L
F
L
D
V
N
T
A
G
L
R
R
P
------
A
K
E
V
-
Y
P
A
P
A
L
L
R
R
A
R
E
L
G
I
G
L
V
L
G
S
D
A
H
R
P
E
E
V
G
---------------------------------------------
29
Fugue
69.73
26%
-60
- C5 -
2YXO
5
?
A:
[1-263]
-
M
V
D
S
H
V
H
T
P
--
L
C
-
G
-
H
A
E
---
G
H
P
E
A
---
Y
L
---------
E
E
A
R
A
K
--
G
L
K
G
V
V
F
----------
T
D
H
S
P
M
P
P
W
Y
D
P
E
S
R
----------
M
R
L
E
A
L
P
F
Y
L
L
A
L
----
E
R
V
R
E
R
A
-
Q
D
L
Y
V
G
I
G
L
E
A
D
F
H
P
G
T
E
G
F
L
A
--
Q
L
L
R
R
Y
P
F
--
D
Y
V
I
G
S
V
H
Y
L
G
A
W
P
--
L
D
H
-
P
D
H
Q
E
E
Y
A
W
R
------
D
L
K
E
V
---
F
R
A
Y
F
Q
E
-
V
E
K
A
A
R
S
G
----
L
F
H
A
I
G
H
L
D
L
P
K
K
F
------
G
H
R
L
P
E
E
A
L
L
E
L
A
E
P
A
L
R
A
V
A
---
E
A
G
L
F
L
D
V
N
T
A
G
L
R
R
P
-
A
-----
K
E
V
-
Y
P
A
P
A
L
L
R
R
A
R
E
L
G
I
G
L
V
L
G
S
D
A
H
R
P
E
E
V
G
--
F
A
F
P
E
V
Q
A
L
L
A
G
L
GFR
E
A
Y
Y
F
V
EG
S
P
V
A
Y
P
L------------
3
PsiBlast_PDB
69.51
27%
-77
- C5 -
2YZ5
5
?
A:
[3-232]
---
D
S
H
V
H
T
P
--
L
C
-
G
-
H
-
A
E
--
G
H
P
E
A
---
Y
L
---------
E
E
A
R
A
K
--
G
L
K
G
V
V
F
----------
T
D
H
S
P
M
P
P
W
Y
------
D
P
E
S
----
R
M
R
L
E
A
L
P
F
Y
L
L
A
L
----
E
R
V
R
E
R
-
A
Q
D
L
Y
V
G
I
G
L
E
A
D
F
H
P
G
T
E
G
F
L
A
--
Q
L
L
R
R
Y
--
P
F
D
Y
V
I
G
S
V
H
Y
L
----
G
A
W
P
L
-
D
H
P
--
D
H
Q
E
E
Y
A
--
W
R
D
L
K
E
V
---
F
R
A
Y
F
Q
E
-
V
E
K
A
--
A
R
S
G
L
F
H
--
A
I
G
H
L
D
L
P
K
K
F
G
H
R
L
P
E
E
A
------
L
L
E
L
A
E
P
A
L
R
A
V
A
---
E
A
G
L
F
L
D
V
N
T
A
G
L
R
R
P
------
A
K
E
V
-
Y
P
A
P
A
L
L
R
R
A
R
E
L
G
I
G
L
V
L
G
S
D
A
H
R
P
E
E
V
G
---------------------------------------------
9
HHSearch
67.75
26%
-67
- C5 -
2YXO
5
?
A:
[1-239]
-
M
V
D
S
H
V
H
T
P
--
L
C
-
G
-
H
A
E
---
G
H
P
E
A
---
Y
L
---------
E
E
A
R
A
K
--
G
L
K
G
V
V
F
----------
T
D
H
S
P
M
P
P
W
Y
D
P
----------
E
S
R
M
R
L
E
A
L
P
F
Y
L
L
A
L
----
E
R
V
R
E
R
A
-
Q
D
L
Y
V
G
I
G
L
E
A
D
F
H
P
G
T
E
G
F
L
A
--
Q
L
L
R
--
R
Y
P
F
D
Y
V
I
G
S
V
H
Y
L
G
A
----
W
P
L
-
D
H
P
D
H
Q
-
E
E
---
Y
A
W
R
D
L
K
E
V
---
F
R
A
Y
F
Q
E
-
V
E
K
A
A
R
----
S
G
L
F
H
A
I
G
H
L
D
L
P
K
K
F
G
H
R
L
P
------
E
E
A
L
L
E
L
A
E
P
A
L
R
A
V
A
---
E
A
G
L
F
L
D
V
N
T
A
G
L
R
R
P
------
A
K
E
V
-
Y
P
A
P
A
L
L
R
R
A
R
E
L
G
I
G
L
V
L
G
S
D
A
H
R
P
E
E
V
G
--
F
A
F
P
E
V
Q
------------------------------------
15
HHSearch
57.95
13%
-78
- C5 -
3B0X
2
?
A:
[337-538]
V
K
G
D
L
Q
V
H
S
T
--
Y
S
---
D
G
Q
---
N
T
L
E
E
---
L
W
---------
E
A
A
K
T
M
--
G
Y
R
Y
L
A
V
----------
T
D
H
S
P
A
V
R
V
A
G
-------------
G
P
S
P
E
E
A
L
K
R
V
G
E
I
----
R
R
F
N
E
T
H
-
G
P
P
Y
L
L
A
G
A
E
V
D
I
H
P
D
G
T
L
D
-----
Y
P
D
W
V
L
R
E
L
D
L
V
L
V
S
V
H
S
R
F
N
----
L
-----
P
K
---------------------
A
D
Q
T
K
R
-
L
L
K
A
L
E
----
N
P
F
V
H
V
L
A
H
P
T
A
R
L
L
G
R
R
-
A
P
---------
I
E
A
D
W
E
A
V
F
Q
K
A
K
---
E
K
G
V
A
V
E
I
D
G
Y
Y
D
R
-----------
M
-
D
L
P
D
D
L
A
R
M
A
Y
G
M
G
L
W
I
S
L
S
T
D
A
H
Q
T
D
H
L
R
--
F
------------------------------------------
11
HHSearch
54.03
17%
-59
- C5 -
1M65
5
YCDX_ECOLI
A:
[2-207]
Y
P
V
D
L
H
M
H
T
V
--
A
S
-
T
-
H
A
Y
---
S
T
L
S
D
---
Y
I
---------
A
Q
A
K
Q
K
--
G
I
K
L
F
A
I
----------
T
D
H
G
P
D
M
E
D
A
P
------------------
H
H
W
H
F
I
N
M
------
R
I
W
P
R
V
V
D
G
V
G
I
L
R
G
I
E
A
N
I
K
N
V
D
G
-
E
I
D
---
C
S
G
K
M
F
D
S
L
D
L
I
I
A
G
F
H
E
P
V
F
----------
A
P
---------------
H
D
---
K
A
T
N
T
Q
A
-
M
I
A
T
I
A
----
S
G
N
V
H
I
I
S
H
P
G
N
P
K
Y
E
I
----------------
D
V
K
A
V
A
E
A
A
A
---
K
H
Q
V
A
L
E
I
N
N
S
S
----------------
N
C
R
E
V
A
A
A
V
R
D
A
G
G
W
V
A
L
G
S
D
S
H
T
A
F
T
M
G
---
E
F
E
E
C
L
K
-----------------------------------
12
HHSearch
49.11
17%
-62
- C5 -
2W9M
3
?
A:
[327-525]
L
R
G
M
I
H
T
H
S
T
--
W
S
---
D
G
G
---
A
S
I
R
E
---
M
A
---------
E
A
T
L
T
L
--
G
H
E
F
L
G
T
----------
A
D
H
S
R
A
A
Y
Y
A
N
-------------
G
L
T
I
E
R
L
R
E
Q
L
K
E
I
----
R
E
L
Q
R
---
A
G
L
P
I
V
A
G
S
E
V
D
I
L
D
D
G
S
L
-----
D
F
P
D
D
V
L
G
E
L
D
Y
V
V
V
S
V
H
S
N
F
T
------
L
---
D
---------------------
A
A
R
Q
T
E
R
-
L
I
R
A
V
S
----
H
P
L
V
T
V
L
G
H
A
T
G
R
L
L
L
R
R
----------
P
G
Y
A
L
D
L
D
A
V
L
G
A
C
E
---
A
N
G
T
V
V
E
I
N
A
N
A
A
R
L
D
-----------
L
D
W
R
E
A
L
R
W
--
R
E
R
L
K
F
A
I
N
T
D
A
H
V
P
G
G
L
R
--
D
------------------------------------------
13
HHSearch
47.32
16%
-55
- C5 -
3QY7
4
YWQE_BACSU
A:
[1-208]
-
M
I
D
I
H
C
H
I
L
PA
M
D
---
D
G
A
G
D
S
A
D
S
I
E
---
M
A
---------
R
A
A
V
R
Q
--
G
I
R
T
I
I
A
----------
T
P
H
H
N
N
G
V
Y
K
N
---------------
E
P
A
A
V
R
E
A
A
D
Q
L
----
N
K
R
L
I
K
E
D
I
P
L
H
V
L
P
G
Q
E
I
R
I
Y
G
E
V
E
Q
D
L
A
K
R
Q
L
L
S
--
L
N
D
T
K
Y
I
L
I
E
---------------
F
P
F
D
---------------
H
---
V
P
R
Y
A
E
Q
L
F
Y
D
L
Q
L
----
K
G
Y
I
P
V
I
A
H
P
E
R
N
R
E
I
R
----------------
E
N
P
S
L
L
Y
H
L
V
---
E
K
G
A
A
S
Q
I
T
S
G
S
L
A
G
I
------
F
G
---
K
Q
L
K
A
F
S
L
R
L
V
E
A
N
L
I
H
F
V
A
S
D
A
H
N
V
K
T
R
N
--
F
H
T
Q
E
A
-------------------------------------
14
HHSearch
47.30
13%
-53
- C5 -
3WYZ
1
?
A:
[20-191]
-------------------------
D
E
E
---
A
H
---------
E
L
A
-
S
D
--
W
F
D
E
V
V
F
----------
T
K
K
L
V
L
E
D
P
P
-------------------
D
W
G
S
L
K
E
E
L
----
K
E
L
R
G
K
Y
-
G
K
V
A
L
L
----
L
V
T
R
K
P
--
S
L
I
R
---
E
V
K
-
S
R
N
L
K
A
--
L
L
Y
V
Q
G
G
D
M
-------------------------------------
R
I
-
N
R
M
A
I
E
----
S
-
G
V
D
A
L
I
S
P
W
F
G
R
K
-
D
P
--------------
G
F
D
H
T
L
A
G
M
A
A
---
R
R
G
V
A
I
G
F
S
L
S
P
L
L
N
A
-
N
P
Y
G
R
A
Q
I
L
-
R
F
M
M
K
T
W
Q
L
V
K
K
Y
R
V
P
R
F
I
T
S
S
A
E
S
R
W
E
V
R
--
G
-
P
R
D
L
-------------------------------------
10
HHSearch
46.87
19%
-54
- C5 -
2WJE
3
CPSB_STRPN
A:
[4-218]
G
M
I
D
I
H
S
H
I
V
--
F
D
V
D
-
D
G
P
---
K
S
R
E
E
S
K
A
L
L
---------
A
E
S
Y
R
Q
--
G
V
R
T
I
V
S
----------
T
S
H
R
R
K
G
M
F
E
T
---------------
P
E
E
K
I
A
E
N
F
L
Q
V
----
R
E
I
A
K
E
V
A
S
D
L
V
I
A
Y
G
A
E
I
Y
Y
T
P
D
V
L
D
K
L
------
E
--
K
K
R
I
-
P
T
L
N
D
S
R
Y
A
L
-------
I
-
E
F
S
M
--------------
N
T
P
---
Y
R
D
I
H
S
--
A
L
S
K
I
L
M
---
L
G
I
T
P
V
I
A
H
I
E
R
Y
D
A
L
E
----------------
N
N
E
K
R
V
R
E
L
I
---
D
M
G
C
Y
T
Q
V
N
S
S
H
V
L
K
P
K
L
----
F
G
E
R
Y
K
F
M
K
K
R
A
Q
Y
F
L
E
Q
D
L
V
H
V
I
A
S
D
M
H
N
L
D
G
R
P
--
P
H
M
A
E
A
Y
------------------------------------
30
Fugue
46.26
17%
-49
- C5 -
1M65
5
YCDX_ECOLI
A:
[2-245]
Y
P
V
D
L
H
M
H
T
V
--
A
S
-
T
-
H
A
-
Y
--
S
T
L
S
D
---
Y
I
---------
A
Q
A
K
Q
K
--
G
I
K
L
F
A
I
----------
T
D
H
G
P
D
M
E
D
A
P
H
H
W
H
F
I
N
M
R
I
------------------------
W
P
R
V
V
D
G
V
G
I
L
R
G
I
E
A
N
--
I
K
N
V
D
G
E
I
--
D
C
S
G
K
M
F
D
S
L
D
L
I
I
A
G
F
H
E
-----------------------------
P
V
F
---
A
P
H
D
K
A
T
-
N
T
Q
A
M
I
A
T
I
A
S
G
N
V
H
I
I
S
H
P
G
----------------
N
P
K
Y
E
I
D
V
K
A
V
A
E
A
A
A
---
K
H
Q
V
A
L
E
I
N
N
---------------
S
-
S
N
C
R
E
V
A
A
A
V
R
D
A
G
G
W
V
A
L
G
S
D
S
H
T
A
F
T
M
G
EF
E
E
C
L
K
I
L
D
A
V
DFPPERILNVS
P
R
R
L
L
N
F
L
E
S
R
GMAPIAEFADL
21
HHSearch
44.69
14%
-43
- C5 -
1V77
-
RNP3_PYRHO
A:
[19-177]
--------------------------------
A
---------
Y
E
L
A
K
E
--
W
F
D
E
V
V
V
----------
S
I
K
F
N
E
E
V
D
K
-------------------------
E
K
L
----
R
E
-------
A
R
K
E
Y
G
K
V
A
I
L
L
S
N
P
K
P
S
L
V
R
--
D
T
V
Q
K
F
K
--
S
Y
L
I
--
Y
V
E
S
N
D
------------
L
-------------------------
R
V
-
I
R
Y
S
I
E
----
K
-
G
V
D
A
I
I
S
P
W
V
N
R
K
D
P
---
G
------------
I
D
H
V
L
A
K
L
M
V
---
K
K
N
V
A
L
G
F
S
L
R
P
L
L
Y
S
-
N
P
Y
E
R
A
N
L
L
-
R
F
M
M
K
A
W
K
L
V
E
K
Y
K
V
R
R
F
L
T
S
S
A
Q
E
K
W
D
V
R
--
Y
------------------------------------------
20
HHSearch
37.98
13%
-27
- C5 -
2HPI
3
DPO3A_THEAQ
A:
[6-279]
K
F
A
H
L
H
Q
H
T
Q
--
F
S
-
L
L
D
G
A
---
A
K
L
Q
D
---
L
L
---------
K
W
V
K
E
T
T
P
E
D
P
A
L
A
M
----------
T
D
H
G
N
L
F
G
A
V
----------------------
E
F
---
Y
----
K
K
A
T
A
---
M
G
V
K
P
I
I
G
Y
E
A
Y
V
A
A
E
S
R
F
D
R
K
--
R
G
-----
G
Y
F
H
L
T
L
L
A
K
D
F
T
G
----
Y
Q
N
L
V
R
L
A
S
R
----------
A
Y
L
E
G
F
YE
K
P
R
I
D
R
E
I
-
L
-
R
E
H
-----
A
Q
G
L
I
A
L
S
G
C
L
G
A
E
I
P
Q
F
I
L
Q
D
----
R
----
L
D
L
A
E
A
R
L
N
E
D
L
S
I
F
G
D
R
F
F
I
E
I
Q
N
H
G
L
P
E
---------
Q
K
-
K
V
N
Q
V
L
K
E
F
A
R
K
Y
G
L
G
M
V
A
T
N
D
G
H
Y
V
R
K
E
D
--
A
R
A
H
E
V
-------------------------------------
19
HHSearch
37.42
13%
-23
- C5 -
2ANU
4
?
A:
[20-219]
L
L
C
D
F
H
V
H
T
N
--
M
S
---
D
G
H
---
L
P
L
G
E
---
V
V
---------
D
L
F
G
K
H
--
G
V
D
V
V
S
I
----------
T
D
H
I
V
D
R
R
T
L
E
Q
R
K
R
N
G
E
P
L
---
G
A
I
T
E
D
K
F
Q
D
Y
L
K
R
L
W
R
E
Q
K
R
A
W
E
E
--
Y
G
M
I
L
I
P
G
V
E
I
T
N
N
T
D
L
Y
H
-
I
V
--
A
V
----
D
V
-
K
E
Y
-
V
------
D
------------
P
---------------------
S
L
P
V
E
E
-
I
V
E
K
L
K
E
---
Q
N
A
L
V
I
A
A
H
P
D
R
K
K
-----
L
S
--------
W
---
Y
L
W
A
N
M
E
R
F
K
---
D
T
F
D
A
W
E
I
A
N
R
D
D
L
-------------------
F
N
S
V
G
V
K
K
Y
R
Y
V
A
N
S
D
F
H
E
L
W
H
V
Y
--
S
W
K
T
L
V
-------------------------------------
26
HHSearch
35.95
6%
-52
- C5 -
3RYS
2
?
A:
[232-284]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
V
V
Q
R
L
V
---
A
E
Q
V
P
L
T
V
C
P
L
S
N
V
R
L
-
R
----
A
V
D
K
--
L
A
D
H
P
L
P
E
M
L
A
I
G
L
N
V
C
V
N
S
D
D
P
A
Y
-------------------------------------------------
25
HHSearch
35.70
4%
-42
- C5 -
3IAR
2
ADA_HUMAN
A:
[245-296]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
Y
N
R
L
R
---
Q
E
N
M
H
F
E
I
C
P
W
S
S
Y
L
T
-
G
----
A
W
K
P
--
D
T
E
H
A
V
I
R
L
K
N
D
Q
A
N
Y
S
L
N
T
D
D
P
L
I
-------------------------------------------------
5
PsiBlast_PDB
34.91
21%
-57
- C4 -
4FNV
-
HEPC_BACTN
A:
[135-253]
V
K
Q
D
G
G
I
N
W
E
--
Y
S
-
P
-
K
D
A
S
--
D
E
Y
Q
K
---
Q
L
H
R
HQW
F
I
P
Q
A
K
A
Y
R
V
--
S
G
D
E
K
Y
I
Q
S
W
I
E
V
Y
K
N
W
I
E
N
N
P
K
P
T
T
G
P
N
T
T
S
W
W
Q
L
Q
V
S
T
R
I
G
D
Q
V
Q
L
L
E
Y
F
K
N
S
----
V
N
F
T
P
E
W
L
S
T
F
L
V
E
F
A
E
Q
A
D
F
L
V
D
Y
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------