@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0601: (2016-03-17 )
MHKHHLSKKLFFAGLVLFIIGAIGVAFTMNTGKMIEKGEPLTKQWDLSTENIKKIAFSSERDASIEWKESTTGKNYIELKGNYSANDKKAIQQLEPVSEDGTSFDITVPEEDDWYNGFGKIYAYGKQKVTIYLTKDTKLADLEVKSHSGDIDVADFKVKKFVSSTNSGELKVTNLEANTAQMATSSGDLTLSNIKANSSIETDSGKTELTNLTGDLEVNGGSGDVNVAGVKAKKLKIAIDSGDIELTSGTVTDLAVLTTSSGDIDANTKGKIQAESDSGSIELAGATNNVTAKTSSGDIDVAFTKQVKNIEINSDSGEVELELPGDFKAIYEASSNSGSVKAPTSDSNTDNRVTVKTSSGDIKIEK
Atome Classification :
(20 SA)
...--......---10........20........30......----..40........50........60........70....---....80........90........100.......110.......120..-.....130......-----------.140.......150..--...---------.-.-160----...-....-.170..-...------------..180.-.-.....-----190.......200.---..-----...----.210.......-220......-------..230.....-.--------.-240---.-....---....250-..-.....260........270...-.-...280--..-......290...-..-....300-.......310.----------------....----..320.......330.......340.-----......350.......360.-...------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
H
K
--
H
H
L
S
K
K
---
L
F
F
A
G
L
V
L
F
I
I
G
AI
G
V
A
F
TMNTGKMIEK----GEPLTKQWDL
S
T
E
N
I
K
K
IAFSSERDA
S
I
E
W
KESTTGK
N
---
Y
I
E
L
KGNYSA
N
D
K
K
A
I
Q
Q
LEPVSEDG
T
S
F
D
I
TVPEED
D
W
Y
NGF
G
K
I
Y
A
Y-G
K
Q
K
V
T
I
Y
L
TKD
T
K
-----------
L
A
D
L
E
V
KSHSGDID
V
A
--
D
F
K
---------
V
-
K
-
K
F
-----
V
SS-TNSG-
E
L
K
V
T
N-LEA------------N
T
A
Q
MA-T-SSG
D
L
-----
T
L
S
N
I
KANSSIETD---SG-----K
T
E
----
L
TN
L
T
G
D
L
E
V
N-G-GSGD
V
N
V
-------AG
V
K
A
K
K
L
K
I
-
A
--------
I
-D-----S-G
D
I
E
---LTSGT
V
T
-
D
L
-
A
V
L
TTS-SGDIDANTKG
K
I
Q
AE-S-DSG
S
I
---
E
L
-AGATN
N
V
--
T
AK-TS-SG
D
I
D
V
A
-
F
T
K
Q
V
K
N
I
E
IN----------------SDS
G
----
E
V
E
L
ELPGD
F
K
A
I
YEASSNSGSVKAP-----TSDSNTD
N
R
V
T
V
K
TSSG
D
I
K
-IEK------
31
Fugue
80.84
21%
-5
- C5 -
3PET
11
?
A:
[4-221]
----------------------------------------------------------------------------------------------------------------
G
I
Q
P
S
K
K
L
I
T
R
D
Y
K
V
K
E
F
N
K
I
D
A
G
-
T
V
G
N
I
Y
Y
T
Q
S
T
D
G
K
T
D
L
Q
I
Y
G
P
D
N
I
V
A
L
I
Q
V
A
V
K
D
N
T
L
F
L
S
--
I
D
K
---------
S
-
K
-
K
V
-------
R
-
N
F
K
K
M
K
I
T
I
T
S
-
P
T
L
------------
N
G
I
S
F
--
K
-
G
V
G
D
V
-----
H
I
E
N
G
L
T
T
D
N
L
D
I
E
S
KG
V
G
-----
N
V
D
----
I
Q
S
L
T
C
Q
K
L
N
V
Q
S
M
G
V
G
D
V
K
L
-------
E
G
-
T
A
Q
I
A
A
L
-
H
--------
S
-
K
-----
G
V
G
N
I
E
---
A
G
N
L
R
A
N
-
A
V
-
E
A
S
S
Q
G
-
V
G
D
I
T
C
N
A
T
E
S
I
D
A
A
V
R
-
G
V
G
S
I
---
K
Y
-
K
G
S
P
T
I
K
--
S
L
S
-
K
K
G
V
G
T
I
K
N
I
-------------------------------------------------------------------------------------------------
22
HHSearch
72.33
18%
-22
- C5 -
3PET
11
?
A:
[9-184]
----------------------------------------------
K
K
L
I
T
R
D
Y
K
V
--
K
E
F
N
K
I
D
A
G
T
--
V
G
N
I
Y
Y
T
Q
S
T
D
G
K
T
---
D
L
Q
I
Y
G
P
--
D
N
I
V
A
L
----
I
Q
V
A
V
K
D
N
T
L
F
L
S
I
D
K
S
K
-
K
V
R
------
N
F
-
K
K
M
K
I
T
I
T
S
P
T
--------------
L
N
G
I
S
F
K
-
G
V
G
D
V
H
I
E
N-
G
L
T
---------
T
-
D
-
N
L
-----
D
I
E
S
K
G
V
G
-
N
V
D
I
Q
S
-
L
T
C
------------
Q
K
L
N
V
Q
-
S
M
G
V
G
D
V
-----
K
L
E
G
T
A
Q
------------------------------
I
A
A
L
H
S
K
-
G
V
G
N
I
E
A
-------
G
N
L
R
A
N
A
V
E
A
-
S
--------
S
Q
G
-----
V
-
G
D
I
T
---
C
N
---------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
Fugue
68.54
16%
4
* C5 *
3JX8
8
?
A:
[4-250]
-------------------------------------
D
K
R
I
D
----
G
N
G
N
P
E
T
R
E
I
K
I
S
D
Y
D
E
I
T
F
V
G
--
S
A
D
F
E
Y
E
Q
S
D
K
A
P
----
Y
L
S
V
T
I
D
-----
E
N
L
F
D
Y
L
V
T
E
V
E
G
G
---
T
L
K
I
Y
P
K
S
I
K
K
G
F
N
N
N
S
Y
D
L
-
R
P
T
V
Y
K
I
K
S
N
S
K
-
E
-----------
L
K
E
L
N
T
V
G
-
S
G
S
F
I
I
S
--
K
P
T
---------
K
-
V
-
N
R
M
----
E
I
N
M
A
G
S
G
-
N
V
E
L
R
G
P
V
K
G
------------
Y
K
L
E
C
N
M
A
-
G
S
G
N
I
-----
I
A
K
D
I
Q
L
D
N
L
S
C
S
L
---
A
S
S
G
---
E
I
E
----
V
I
G
T
V
D
R
A
S
F
N
-
V
A
G
S
G
E
I
K
A
-------
F
D
C
Q
A
R
K
A
E
C
-
N
--------
I
-
A
-------
S
S
G
E
---
I
S
V
Y
A
T
Q
-
I
L
-
D
A
N
I
V
G
-
S
G
E
I
H
Y
K
G
D
P
E
I
S
K
S
-
I
M
G
S
G
S
I
---
N
K
-
V
K
----------------------------------------------------------------------------------------------------------------------
32
Fugue
66.72
16%
34
* C2 *
3S40
-
?
A:
[3-300]
--
K
--
T
K
F
E
K
----------
V
L
L
I
V
N
P
-----
K
A
G
Q
G
D
L
H
T
N
----
L
T
K
I
V
P
P
L
A
A
A
F
P
D
L
H
I
L
H
T
K
E
Q
G
D
A
T
K
Y
C
Q
E
F
A
S
K
V
D
---
L
I
I
V
F
G
G
-
D
G
T
V
F
E
C
T
N
G
L
A
P
L
E
I
R
P
T
L
A
I
I
P
G
G
T
C
N
D
F
S
R
T
L
G
-------------
V
P
Q
N
I
A
E
-----------
A
A
K
L
I
T
K
E
H
V
K
P
V
D
V
A
--
K
A
N
---------
G
-
Q
-
H
F
-----
L
N
F
-
W
G
I
G
-
K
I
G
Y
Y
---------------------------------------------------------------------------------------
L
-------
S
T
I
E
T
F
P
V
K
I
-
T
--------
Y
-
D
-----
G
----
Q
---
V
Y
E
D
E
A
V
-
L
V
M
V
G
N
G
E
Y
-
L
G
G
I
P
S
F
I
P
N
-----------------------------
V
K
-
C
D
-
D
G
T
L
D
I
F
-
V
V
K
S
T
G
I
Q
A
F
K
----------------
D
Y
I
G
----
K
K
L
F
E
D
S
N
E
-
N
D
I
F
H
V
K
A
K
S
I
H
I
E
T
E
E
E
K
E
V
D
T
D
S
S
L
H
T
P
C
Q
I
E
L
L
Q
G
H
F
T
M
I
Y
N
PAVV--
6
PsiBlast_PDB
64.62
21%
-4
* C6 *
4AQ1
2
?
A:
[390-549]
------------------------------------------------------------------------------------------------------------------------------------
M
F
A
G
-
E
T
K
T
V
A
M
Y
---
D
T
K
-----------
N
G
D
P
E
T
K
P
----
V
D
F
K
--
D
A
T
---------
V
-
R
-
S
L
NPII
A
T
A
A
-
I
N
G
S
-
E
L
L
V
T
----
A
------------
N
A
G
Q
S
G
-
K
-
A
S
F
E
V
-----
T
F
K
D
---------
N
---
T
K
-----
R
T
--------
F
T
V
D
V
K
K
E
-
P
-
V
L
Q
D
I
K
V
-------
D
A
T
S
V
K
L
S
D
E
-
A
--------
V
-
G
-----
G
-
G
E
V
E
---
G
V
N
Q
K
T
I
-
K
V
-
S
A
V
D
Q
Y
-
G
K
E
I
K
F
G
T
K
G
K
V
T
V
T
-
T
-
N
T
E
G
L
---
V
I
-
K
N
V
N
S
D
N
--
T
I
D
-
F
D
-
S
G
N
-----------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
62.41
26%
6
- C5 -
3RGZ
3
BRI1_ARATH
A:
[84-225]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
N
S
H
I
N
G
S
V
S
G
F
---
K
C
-----
S
A
S
----
L
T
S
L
--
D
L
S
R
N
-
S
-
L
S
G
P
V
T
T
LTSLGSC
S
G
L
K
F
L
N
V
S
S
N
T
--------
L
-
D
F
P
G
KV
S
-
G
G
L
K
---
L
N
S
L
E
V
L
-
D
L
-
S
A
N
S
I
S
-
G
----
A
N
V
V
G
W
V
L
S
D
-
G
-
C
G
E
L
K
---
H
L
-
A
I
S
G
N
K
I
---------
S
G
D
V
D
V
S
-
R
C
V
N
L
E
F
L
D
V
S
----------------
S
N
N
F
----
S
T
G
I
P
F
L
G
D
C
S
A
L
------------------------------------------------
7
PsiBlast_PDB
62.01
26%
13
- C5 -
3RGX
3
BRI1_ARATH
A:
[84-233]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
N
S
H
I
N
G
S
V
S
G
F
---
K
C
-----
S
A
S
----
L
T
S
L
--
D
L
S
R
N
-
S
-
L
S
G
P
V
T
T
LTSLGSC
S
G
L
K
F
L
N
V
S
S
N
T
--------
L
-
D
F
P
G
KV
S
-
G
G
L
K
---
L
N
S
L
E
V
L
-
D
L
-
S
A
N
S
I
S
-
G
----
A
N
V
V
G
W
V
L
S
D
-
G
-
C
G
E
L
K
---
H
L
-
A
I
S
G
N
K
I
---------
S
G
D
V
D
V
S
-
R
C
V
N
L
E
F
L
D
V
S
----------------
S
N
N
F
----
S
T
G
I
P
F
L
G
D
C
S
A
L
------------------------------------------------
34
Fugue
61.50
19%
6
- C5 -
4QRK
2
?
A:
[9-220]
---------------------------------------------------------------------------------------------------------------------------------------
K
-
P
K
E
E
I
K
I
V
E
P
N
G
A
E
-----------
K
T
K
L
N
L
N
F
G
V
G
K
L
N
I
S
G
N
E
E
K
---------
L
M
K
G
K
F
-----
I
Y
S
-
E
N
E
W
-
K
P
E
I
K
Y
-
E
V
K
------------
D
--------
K
D
G
E
L
-----
E
I
S
Q
P
G
L
K
S
---------
G
-----
N
V
S
----
L
N
N
K
R
N
E
W
N
I
N
-
L
-
N
E
K
I
P
T
E
-------
I
K
L
S
L
G
T
G
E
F
-
K
--------
A
-
D
-----
L
-
S
K
I
N
---
L
K
E
L
N
V
G
M
G
V
-
G
K
V
D
L
D
I
S
G
N
Y
K
N
N
V
K
V
N
I
E
G
G
-
V
-
G
E
A
T
V
---
Y
L
P
K
S
I
G
V
K
I
--
K
A
E
-
K
G
-
V
G
A
V
N
A
N
G
F
I
V
E
G
E
N
I
Y
K
N
----------------
S
Q
Y
G
KSK
N
S
I
E
V
N
I
E
A
G
V
G
A
I
N
I
K
Q
K
-------------------------------------------
10
PsiBlast_PDB
60.51
26%
13
- C5 -
3RJ0
4
BRI1_ARATH
A:
[81-224]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
N
S
H
I
N
G
S
V
S
G
F
---
K
C
-----
S
A
S
----
L
T
S
L
--
D
L
S
R
N
-
S
-
L
S
G
P
V
T
T
LTSLGSC
S
G
L
K
F
L
N
V
S
S
N
T
--------
L
-
D
F
P
G
KV
S
-
G
G
L
K
---
L
N
S
L
E
V
L
-
D
L
-
S
A
N
S
I
S
-
G
----
A
N
V
V
G
W
V
L
S
D
-
G
-
C
G
E
L
K
---
H
L
-
A
I
S
G
N
K
I
---------
S
G
D
V
D
V
S
-
R
C
V
N
L
E
F
L
D
V
S
----------------
S
N
N
F
----
S
T
G
I
P
F
L
G
D
C
S
A
L
------------------------------------------------
11
PsiBlast_PDB
60.47
26%
16
- C5 -
4LSX
2
BRI1_ARATH
A:
[83-224]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
N
S
H
I
N
G
S
V
S
G
F
---
K
C
-----
S
A
S
----
L
T
S
L
--
D
L
S
R
N
-
S
-
L
S
G
P
V
T
T
LTSLGSC
S
G
L
K
F
L
N
V
S
S
N
T
--------
L
-
D
F
P
G
KV
S
-
G
G
L
K
---
L
N
S
L
E
V
L
-
D
L
-
S
A
N
S
I
S
-
G
----
A
N
V
V
G
W
V
L
S
D
-
G
-
C
G
E
L
K
---
H
L
-
A
I
S
G
N
K
I
---------
S
G
D
V
D
V
S
-
R
C
V
N
L
E
F
L
D
V
S
----------------
S
N
N
F
----
S
T
G
I
P
F
L
G
D
C
S
A
L
------------------------------------------------
12
PsiBlast_PDB
60.06
26%
17
- C5 -
4M7E
1
BRI1_ARATH
A:
[83-224]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
N
S
H
I
N
G
S
V
S
G
F
---
K
C
-----
S
A
S
----
L
T
S
L
--
D
L
S
R
N
-
S
-
L
S
G
P
V
T
T
LTSLGSC
S
G
L
K
F
L
N
V
S
S
N
T
--------
L
-
D
FPGKV
S
-
G
G
L
K
---
L
N
S
L
E
V
L
-
D
L
-
S
A
N
S
I
S
-
G
----
A
N
V
V
G
W
V
L
S
D
-
G
-
C
G
E
L
K
---
H
L
-
A
I
S
G
N
K
I
---------
S
G
D
V
D
V
S
-
R
C
V
N
L
E
F
L
D
V
S
----------------
S
N
N
F
----
S
T
G
I
P
F
L
G
D
C
S
A
L
------------------------------------------------
18
PsiBlast_PDB
59.92
21%
23
- C7 -
4O3Y
1
?
A:
[353-511]
------------------------------------------------------------------------------------------------------------------------------
Y
M
K
F
G
Q
L
W
Q
K
E
G
E
Q
------
T
K
D
N
S
-----------
L
F
L
Q
G
E
R
T
A
T
D
K
I
P
V
G
G
-
N
Y
K
Y
--------
V
-
G
-
T
W
-----
D
A
L
-
V
S
K
G
-
T
N
W
V
A
E
-
A
D
N
------------
N
R
E
S
G
Y
-
R
-
S
E
F
D
V
-----
N
F
G
D
K
K
V
S
G
K
L
F
D
K
---
G
G
-----
I
V
P
----
V
F
M
I
N
A
D
I
K
G
N
-
G
-
F
T
G
T
A
N
T
-------
T
D
T
G
-----
F
-
A
--------
L
-
D
-----
S
---
S
Q
---
H
G
N
A
V
F
S
-
D
I
-
K
V
N
G
G
F
-
Y
G
P
T
A
G
E
L
G
G
Q
F
H
H
K
-
S
-
D
N
G
S
V
------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
59.48
21%
23
- C7 -
4O49
1
?
A:
[353-511]
------------------------------------------------------------------------------------------------------------------------------
Y
M
K
F
G
Q
L
W
Q
K
E
G
E
Q
------
T
K
D
N
S
-----------
L
F
L
Q
G
E
R
T
A
T
D
K
I
P
V
G
G
-
N
Y
K
Y
--------
V
-
G
-
T
W
-----
D
A
L
-
V
S
K
G
-
T
N
W
V
A
E
-
A
D
N
------------
N
R
E
S
G
Y
-
R
-
S
E
F
D
V
-----
N
F
G
D
K
K
V
S
G
K
L
F
D
K
---
G
G
-----
I
V
P
----
V
F
M
I
N
A
D
I
K
G
N
-
G
-
F
T
G
T
A
N
T
-------
T
D
T
G
-----
F
-
A
--------
L
-
D
-----
S
----
Q
---
H
G
N
A
V
F
S
-
D
I
-
K
V
N
G
G
F
-
Y
G
P
T
A
G
E
L
G
G
Q
F
H
H
K
-
S
-
D
N
G
S
V
------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
59.36
25%
-24
- C5 -
3PET
4
?
A:
[131-202]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
L
N
V
Q
-
S
M
G
V
G
D
V
K
L
-------
E
G
T
-
A
Q
I
A
A
L
-
H
--------
S
K
G
-----
V
-
G
N
I
E
---
A
G
N
L
R
---------------------
A
N
A
V
E
A
S
S
Q
-
G
V
G
D
I
---
T
C
-
N
A
T
-
E
S
I
--
D
A
A
V
R
G
-
V
G
S
I
K
Y
K
-------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
58.96
21%
28
* C7 *
4O3Z
5
?
A:
[353-511]
------------------------------------------------------------------------------------------------------------------------------
Y
M
K
F
G
Q
L
W
Q
K
E
G
E
Q
------
T
K
D
N
S
-----------
L
F
L
Q
G
E
R
T
A
T
D
K
I
P
V
G
G
-
N
Y
K
Y
--------
V
-
G
-
T
W
-----
D
A
L
-
V
S
K
G
-
T
N
W
V
A
E
-
A
D
N
------------
N
R
E
S
G
Y
-
R
-
S
E
F
D
V
-----
N
F
G
D
K
K
V
S
G
K
L
F
D
K
---
G
G
-----
I
V
P
----
V
F
M
I
N
A
D
I
K
G
N
-
G
-
F
T
G
T
A
N
T
-------
T
D
T
G
-----
F
-
A
--------
L
-
D
-----
S
----
Q
---
H
G
N
A
V
F
S
-
D
I
-
K
V
N
G
G
F
-
Y
G
P
T
A
G
E
L
G
G
Q
F
H
H
K
-
S
-
D
N
G
S
V
------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
58.91
26%
13
- C5 -
3RIZ
3
BRI1_ARATH
A:
[81-225]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
N
S
H
I
N
G
S
V
S
G
F
---
K
C
-----
S
A
S
----
L
T
S
L
--
D
L
S
R
N
-
S
-
L
S
G
P
V
T
T
LTSLGSC
S
G
L
K
F
L
N
V
S
S
N
T
--------
L
-
D
F
P
G
KV
S
-
G
G
L
K
---
L
N
S
L
E
V
L
-
D
L
-
S
A
N
S
I
S
-
G
----
A
N
V
V
G
W
V
L
S
D
-
G
-
C
G
E
L
K
---
H
L
-
A
I
S
G
N
K
I
---------
S
G
D
V
D
V
S
-
R
C
V
N
L
E
F
L
D
V
S
----------------
S
N
N
F
----
S
T
G
I
P
F
L
G
D
C
S
A
L
------------------------------------------------
15
PsiBlast_PDB
57.81
21%
28
- C7 -
3PQS
3
?
A:
[351-509]
------------------------------------------------------------------------------------------------------------------------------
Y
M
K
F
G
Q
L
W
Q
K
E
G
E
Q
------
T
K
D
N
S
-----------
L
F
L
Q
G
E
R
T
A
T
D
K
I
P
V
G
G
-
N
Y
K
Y
--------
V
-
G
-
T
W
-----
D
A
L
-
V
S
K
G
-
T
N
W
V
A
E
-
A
D
N
------------
N
R
E
S
G
Y
-
R
-
S
E
F
D
V
-----
N
F
G
D
K
K
V
S
G
K
L
F
D
K
---
G
G
-----
I
V
P
----
V
F
M
I
N
A
D
I
K
G
N
-
G
-
F
T
G
T
A
N
T
-------
T
D
T
G
-----
F
-
A
--------
L
-
D
-----
S
-
G
S
S
Q
---
H
G
N
A
V
F
S
-
D
I
-
K
V
N
G
G
F
-
Y
G
P
T
A
G
E
L
G
G
Q
F
H
H
K
-
S
-
D
N
G
S
V
------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
56.15
24%
45
- C3 -
3PWX
1
?
A:
[3-182]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
S
D
-
D
P
M
A
-
S
I
K
L
L
N
-
L
E
R
------------
E
N
S
A
I
A
-
Q
-
Y
Q
S
N
I
A
N
L
K
T
T
L
S
S
Q
E
T
H
L
D
S
V
S
E
---
S
L
-----
K
S
M
R
D
I
V
L
W
G
A
N
G
S
L
T
D
Q
-
D
-
R
S
G
M
I
T
E
-------
L
K
S
Y
R
D
S
I
E
S
-
S
--------
F
-
N
-----
A
-
Q
D
E
E
GHF
L
F
S
G
T
K
T
-
D
T
-
A
A
L
N
K
S
-
S
G
A
Y
------
V
V
E
G
N
-
S
-
D
V
R
V
V
---
T
V
-
A
K
G
V
T
M
D
--
S
N
M
-
T
A
-
Q
E
I
L
D
I
G
-
G
G
K
N
V
L
N
-
Q
I
D
----------------
A
L
I
A
----
E
F
E
K
P
S
P
-
N
F
Q
A
E
V
D
A
S
L
N
A
-----------------------------------------
33
Fugue
55.35
11%
21
* C4 *
1UYP
6
BFRA_THEMA
A:
[1-432]
L
F
K
PN
Y
H
F
F
P
I
TGW
M
N
D
P
N
G
L
I
F
W
K
G
K
Y
H
M
F
Y
Q
Y
N
P
R
K
P
E
W
G
N
I
C
W
G
H
A
V
S
D
--
D
L
V
H
W
R
H
L
P
V
A
L
Y
P
D
D
E
T
H
G
V
F
S
G
S
A
V
E
K
D
G
K
M
F
L
V
Y
T
Y
Y
R
D
P
T
H
N
K
G
E
K
E
T
Q
C
V
V
M
S
E
N
G
L
D
F
V
K
Y
D
G
N
P
V
I
S
K
P
P
E
E
G
T
H
-
A
F
R
D
P
K
V
N
R
S
N
G
E
W
-----------
R
M
V
L
G
S
G
K
D
E
K
I
G
R
V
L
--
L
Y
T
S
DDLF
H
W
K
Y
E
-
G
-
A
I
-----
F
E
D
-
E
T
T
K
-
E
I
E
C
P
D
-
L
V
R
I
GE
K
D
I
L
I
Y
S
I
T
S
T
N
S
V
L
-
F
-
S
M
G
E
L
-----
K
E
G
K
L
N
V
E
K
R
G
L
L
D
---
H
G
T
D
F
Y
A
A
Q
T
----
F
F
G
T
D
R
V
V
V
I
G
-
W
-
L
Q
S
W
L
R
T
-------
G
L
Y
P
T
K
R
E
G
W
-
N
G
V
M
S
L
P
R
E
L
-
Y
-----
V
-
E
N
N
E
---
L
K
V
K
P
V
D
-
E
L
-
L
A
L
R
K
R
-
K
V
F
E
T
A
K
S
G
T
F
L
L
D
V
-
K
-
E
N
S
Y
E
---
I
V
-
C
E
F
S
G
E
I
--
E
L
R
-
M
G
-
N
E
S
E
E
V
V
-
I
T
K
S
R
D
E
L
I
V
D
TTRSGVS
G
G
E
V
R
K
S
T
V
E
D
E
A
----
T
N
R
I
R
A
F
L
D
S
C
S
V
E
F
F
F
N
D
S
I
A
F
S
F
R
-----
I
H
P
E
N
V
Y
N
I
L
S
V
K
S
N
Q
V
K
L
E
-
V
F
E
L
E
NIWL
2
PsiBlast_PDB
49.31
25%
120
- C- -
4BML
-
?
A:
[209-331]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
S
V
D
T
N
---
I
L
-----
N
R
E
----
I
G
N
S
Q
G
D
M
--
N
-
S
-
G
K
G
L
Y
S
I
-------
A
G
I
R
I
L
K
S
N
N
-
L
--------
A
-
G
-----
L
-
Y
G
Q
D
---
L
S
S
A
A
V
T
-
G
--------------
E
N
N
D
Y
Q
V
D
A
S
-
A
-
L
A
G
L
I
F
H
R
E
A
-
A
G
C
I
Q
S
V
A
P
T
I
Q
-
T
T
-
S
G
D
F
N
V
Q
-
Y
Q
G
D
L
I
V
G
K
L
A
----------------
M
G
C
G
----
S
L
R
T
S
V
A
G
S
F
Q
A
-------------------------------------------------