@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0626: (2016-03-17 )
MWKKHKWLIIAVLLLVIYVAPLFILGGNSHVRIHDNLDSNVTWYKMVLDSGDYTAKVGTANIDQIMDDSVPRDSFDSEFVGIDWLYMIFSTPIAFAMSQLITRVFAFLGLFLWARDYLIKDKKYLVPIYFVSLAFALTPFWPSGMLSTLGMPLALWAFLNIRNNKRRIWNVVILTLLPFYSSLILGFCFFLVMVGCIWLYDVFKKKQVHIRFLLSMLYMGLIYVIVNYRFIYAMFLHPEPDSRSEFSLPNLSFLSSIRLSFKNFIFGHTHDQALAGYVILPILLLVLVLIIIKREWVKEKLFLWLFGFNLFLSFWYGFWWYRGWNVIKEHVEIMRTFNFSRFHFLQPFLFYGLFALAIVYLIKKGNWWRKLAYVAIVLQLIVVFANNSEIYYRTGNGSPSINQFYATEQMEEIKDYIGKPQSSYRVGSIGLHPSVSQESGFYTVDGYVNSYPLAYKRAFRKIIAGELDKSPVLEDYYDNWGNRCYIFSAELGKNYDFGKDSKKHIKQLDFNTEAFKKVGGEYVLSAVPIDNASEVGLQFEKAFDNKESYWKIYLYKATN
Atome Classification :
(20 SA)
-------------------.........10........20........30........40-........50.......--.60-.........70........80-.......-----..90........100---------........110.....---..120.------.....--.130--.......140----.---------.-----.----.....150----------...------....160....-...170.......180..----..------------------...190....---------...200.......210...--....220.......230.......240...----------------....250---------........---------.260.......270...-....280.....-..290-----........300...-..--------------------------..310...-----....-320.-------------------------......-----330.....-..340....-----------------.--------..--------350...-----------------------------....360.--......370.......380-----.......----..390..-.------....400-........410.......420-------.......--430.......440.......450......-.460--------.........470.......480........490.......500.......----510........-520.......530.......540.......550.......-------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------------------MWKK
H
K
W
L
I
I
A
V
L
L
L
V
I
Y
V
A
P
L
F
I
LGGN
S
H
V
R
I
HDNLDSN
V
-
T
W
Y
K
M
V
LDSGD
Y
T
A
KVG--T
A
--
N
I
D
Q
I
MDDSVPRDSFDSE
F
V
--
G
I
D
W
L
Y
M
-----
I
FS
T
P
I
A
F
A
M
S
Q
L
I
----------
T
R
V
F
A
F
L
G
L
F
L
W
A
R
D
Y
---LIKDK
K
------
Y
L
V
P
I
--
Y
F
V
S
--
L
A
F
A
LTPFW-----P---------S-----
G
----
M
L
S
TLG
M
P
----------
L
A
L
------
W
A
F
L
NIRNNK
R
-
R
I
W
N
V
V
I
L
T
L
L
P
F
Y
S
S
L
I
----
L
G
------------------
F
C
F
F
L
V
M
V
G
C
---------
I
W
L
Y
D
V
F
K
KK
Q
V
H
I
R
F
L
L
S
--
M
L
Y
M
G
L
I
Y
V
I
V
N
Y
R
F
I
Y
A
M
F
LHPEPDSRSE----------------FSLP
N
-----------
L
S
F
L
S
S
I
R
---------
L
S
F
K
N
F
IFGHTH
D
Q
A
L
A
-
G
Y
V
I
L
P
I
L
L
L
V
L
-
V
L
I
I
------
I
K
R
E
W
V
K
E
K
L
F
L
W
L
-
F
G
--------------------------
F
N
L
F
L
S
F
W
-----
Y
G
F
W
-
W
Y
R
G
-------------------------
W
N
V
I
K
E
-----
H
V
E
I
M
R
TF-NF
S
R
F
H
F
L
Q
-----------------
P
--------
F
L
--------
F
Y
G
L
F
A
-----------------------------
L
A
I
V
Y
L
IK--KG
N
W
W
R
K
L
A
Y
V
A
I
V
L
Q
L
-------
I
V
V
F
ANN----
S
E
I
Y
Y
RT-G------NGSPS
I
--
N
Q
F
Y
A
T
E
Q
M
E
E
I
K
D
Y
IGKPQS-------S
Y
R
VGSI--GLHPSVSQESG
F
Y
T
VDGYVNSY
P
L
A
Y
K
R
A
-
F
R
----------
K
I
I
A
GELDKSP
V
L
E
D
Y
Y
D
NW-G
N
R
C
Y
I
F
SAELGKNYDFGK
D
S
K
K
H
I
K
Q
LD----F-
N
T
E
A
F
K
KVG-G
E
Y
V
L
S
AVPIDN
A
S
E
V
G
L
Q
F
E
K
AFDNKE
S
Y
W
K
I
Y
L
Y
KATN-------------------
34
Fugue
90.25
16%
-94
- C5 -
4UI9
-
APC5_HUMAN
O:
[27-756]
KDWVTPYKIAVLVLLSEMS
R
T
G
E
G
A
V
S
L
V
E
R
R
R
L
N
Q
Q
L
L
P
L
L
Q
G
P
D
I
T
V
S
K
L
L
K
L
I
E
E
S
C
P
Q
L
A
N
S
V
Q
I
R
I
K
L
M
A
E
G
E
--
L
K
--
D
M
E
Q
F
F
D
D
L
S
D
S
F
S
G
T
E
P
E
V
--
H
K
T
S
V
V
G
-----
L
F
L
R
H
M
I
L
A
Y
S
K
L
------------
S
F
S
Q
V
F
K
L
Y
T
A
L
Q
Q
Y
---
F
Q
S
D
E
N
KKPLSQ
K
Q
A
E
F
--
F
L
S
Q
--
Q
A
S
L
L
K
N
D
E
TKALT
P
---------
A
-----
S
----
L
Q
K
E
L
N
N
L
----------
L
K
F
NPDFAE
A
H
Y
L
S
Y
L
N
N
L
R
V
Q
D
V
F
S
S
T
H
S
L
L
H
Y
F
D
R
L
I
----
L
T
GAESKSNGEEGYGRSLRY
A
A
L
N
L
A
A
L
H
C
RFGHYQQAE
L
A
L
Q
E
A
I
R
I
A
Q
E
S
N
D
H
V
C
L
--
Q
H
C
L
S
W
L
Y
V
L
G
Q
K
R
S
D
S
Y
V
L
L
E
H
S
V
K
K
A
V
H
----------------
F
G
L
P
Y
-----------
L
A
S
L
G
I
Q
S
---------
L
V
Q
Q
R
A
F
A
G
K
T
A
N
K
L
M
D
-
A
L
K
D
S
D
L
L
H
W
K
H
S
L
S
E
L
------
I
D
I
S
I
A
Q
K
T
A
I
W
R
L
-
Y
G
RSTMALQQAQMLLSMNSLEQQNNTES
F
A
V
A
L
C
H
L
-----
A
E
L
H
-
A
E
Q
G
CFAAASEVLKHLKERFPPNSQHAQL
W
M
L
C
D
Q
-----
K
I
Q
F
D
R
A
M
-
N
D
G
K
Y
H
L
A
D
-----------------
S
--------
L
V
TGITALNS
I
E
G
V
Y
R
-----------------------------
K
A
V
V
L
Q
A
Q
NQ
M
S
E
A
H
K
L
L
Q
K
L
L
V
H
C
Q
K
LKNTEMV
I
S
V
L
L
S
V
----
A
E
L
Y
W
R
S
-
S
------
S
--------
P
T
I
A
L
P
M
L
L
Q
A
L
A
L
S
K
E
Y
R
L
-------
Q
Y
L
A
S
E
T
--
V
L
N
L
A
F
A
Q
L
I
---------
L
G
I
P
E
Q
A
L
S
L
-
L
H
----------
M
A
I
E
P
I
L
A
D
G
A
I
L
D
K
G
R
A
M
F
L
V
A
K
C
Q
V
A
S
A
A
S
Y
D
Q
P
K
K
A
E
A
L
E
A
A
I
E
N
L
N
----
E
-
A
K
N
Y
F
A
K
V
D
C
K
E
R
I
R
D
V
V
Y
F
Q
A
R
L
Y
H
T
L
G
K
T
Q
E
R
N
R
C
A
M
L
F
R
Q
L
H
Q
E
L
P
S
VPLINHL------------
38
Fugue
83.18
17%
-81
- C2 -
4K3C
-
?
A:
[1-532]
-----------------------------------
Y
N
I
S
E
M
R
I
I
G
D
T
Q
K
--
L
D
N
E
L
N
Q
L
L
-
T
H
F
K
----
A
G
Q
L
F
R
K
T
E
--
L
S
--
I
I
E
E
Q
I
K
Q
I
L
G
D
R
G
Y
G
S
A
K
V
--
D
L
Y
P
K
F
N
EEDHT
V
Q
I
N
F
I
V
D
A
G
R
R
I
Y
----------
V
R
K
I
R
F
E
G
N
D
V
T
A
D
S
T
---
L
R
R
E
M
R
------
Q
Q
E
G
A
--
W
L
S
T
S
A
V
S
L
A
K
S
R
L
E
-----
R
---------
T
-----
G
----
F
Y
E
T
V
E
M
S
M
P
T
VKNTDD
Q
V
D
I
------
I
Y
K
I
K
E
R
N
T
G
S
-
I
N
F
G
V
G
Y
G
S
G
S
G
L
S
Y
N
A
G
----
I
T
------------------
Q
D
N
F
L
G
M
G
S
S
---------
L
G
L
N
G
S
R
N
T
D
S
T
N
V
N
L
S
Y
T
--
E
P
Y
F
T
K
D
G
V
S
L
G
G
N
I
F
Y
E
D
Y
D
N
S
A
R
K
A
S
A
A
----------------
Y
--
K
R
-----------
K
T
Y
G
A
S
G
T
---------
L
G
F
P
V
-------
D
E
N
N
S
-
Y
Y
L
G
L
G
Y
T
H
D
K
L
-
R
N
V
--------
E
R
E
Y
T
R
E
K
Y
V
N
S
M
K
F
P
--------------------------
I
N
P
Q
N
S
H
Y
D
R
I
Q
S
A
D
F
D
-
L
S
F
G
-------------------------
W
N
Y
N
N
L
-----
N
R
G
Y
F
P
T
A
-
G
S
S
A
N
I
S
G
K
-----------------
L
T
L
PGSDN
K
Y
Y
--------
Q
V
G
T
N
F
-----------------------------
S
G
Y
I
P
L
N
S
--
E
H
K
W
----------------------
V
I
A
T
K
----
G
G
L
A
Y
T
N
-
S
------
F
G
G
K
E
V
PF
Y
Q
L
Y
S
A
G
G
M
G
S
L
R
G
F
A
G
---------------
G
S
I
--
G
P
K
A
I
Y
Y
R
E
D
G
F
K
A
P
S
Q
D
V
I
G
G
N
A
M
V
N
A
S
-
L
E
----------
L
I
I
P
A
P
F
I
S
D
K
----
Y
Q
H
N
V
-
R
T
S
V
F
V
D
A
A
T
V
W
-
N
T
K
W
K
Q
S
K
A
D
Y
P
N
L
P
D
----
F
G
D
Y
K
R
V
R
A
S
A
-
G
I
A
L
Q
W
Q
S
P
I
G
P
L
S
F
S
Y
A
K
P
I
K
K
Y
A
G
D
E
I
E
Q
F
Q
F
T
V
G
S
T
F
-------------------
37
Fugue
82.01
13%
-115
- C9 -
3NZT
12
?
A:
[26-525]
-------------------
Y
D
F
K
K
I
N
N
L
R
G
I
E
R
E
T
L
R
V
T
D
C
G
N
L
A
T
S
N
H
---
P
D
G
L
G
H
K
L
-
T
N
N
S
I
T
V
D
F
S
E
N
L
L
E
L
I
--
T
K
--
P
H
D
S
-------------------
I
D
K
A
I
G
-----
E
L
Y
Q
L
S
A
F
T
L
D
N
M
H
----------
S
------
D
E
I
I
L
N
T
S
M
---
P
L
S
A
N
D
------
N
D
I
Q
E
AD
F
G
S
S
--
N
S
G
R
M
K
R
V
Y
-----
R
---------
K
-----
G
----
L
S
A
R
Y
G
K
I
----------
M
Q
I
-----------------------------------
I
----
S
G
------------------
I
H
Y
N
F
S
F
D
--------------
K
D
L
I
S
N
I
A
T
N
K
Q
V
S
I
S
--
D
I
Y
F
D
V
L
N
N
Y
F
E
F
M
W
L
L
P
Y
L
F
G
A
S
P
I
C
A
K
T
----------------
S
V
K
N
K
-----------
P
D
Y
L
S
V
L
D
DKFYVGEYA
T
S
L
R
M
S
D
L
G
S
P
A
Q
K
D
L
A
I
S
Y
D
N
V
K
A
Y
V
K
D
L
-
I
Q
A
T
D
DTF
A
D
Y
K
R
I
G
L
Y
N
S
Q
G
Q
R
I
-
Q
L
--------------------------
N
D
G
I
L
Q
I
E
-----
N
E
Y
Y
S
A
I
R
P
-------------------------
K
Q
I
A
K
R
-----
G
E
R
P
A
C
A
L
-
Y
N
R
G
V
E
Y
V
E
V
R
VLDVDPFEPVGIS
K
D
T
--------
A
L
--------
F
V
E
V
M
L
-----------------------------
M
T
C
L
D
K
D
A
--
K
K
Y
H
K
D
I
I
K
Q
A
K
Q
N
L
T
A
-------
V
A
I
Q
G
R
N
----
P
Q
L
K
L
K
K
L
D
------
D
D
S
E
I
L
--
L
K
D
Y
A
L
E
L
F
D
E
I
E
A
V
A
K
K
M
P
------------------------------------
K
E
Y
L
D
A
V
E
I
Q
-
K
R
----------
K
V
L
D
I
S
Q
T
P
S
A
K
I
I
E
L
A
R
Q
H
-
G
Y
K
K
F
I
L
D
I
S
R
R
V
S
Q
Q
F
R
S
Y
E
L
P
A
A
I
V
A
K
----
L
-
K
D
Q
A
G
Q
S
V
A
-
A
E
K
E
L
V
A
N
D
K
I
S
L
D
E
Y
I
N
R
Y
Y
K
S
S
K
G
C
C
-------------------------------
31
Fugue
75.00
9%
-108
* C9 *
1VA6
7
GSH1_ECOLI
A:
[1-515]
-------------------
M
I
P
D
V
S
Q
A
L
A
W
L
E
K
H
P
Q
A
L
K
G
I
Q
R
G
L
E
R
E
T
L
R
V
N
A
D
-------------------
G
T
L
A
--
T
T
--
G
H
P
E
A
L
G
S
A
L
T
H
K
W
I
T
T
D
F
A
--
E
A
---
L
L
-----
E
F
I
T
P
V
D
----
G
D
I
----------
E
H
M
L
T
F
M
R
D
L
H
R
Y
T
A
R
---
N
M
G
D
E
----------------
R
M
--
W
P
L
S
M
P
S
Y
I
-----
A
---------
E
-----
G
--------
Q
D
I
E
----------
L
A
Q
------
Y
G
T
S
N
-
T
G
R
F
K
-
T
L
Y
R
E
G
L
K
N
R
Y
G
A
L
M
Q
T
I
----
S
G
------------------
V
H
Y
N
F
S
L
P
M
A
---------
F
W
Q
A
K
S
G
D
I
S
G
A
D
A
K
E
K
I
S
--
A
G
Y
F
R
V
I
R
N
Y
Y
R
F
G
W
V
I
P
Y
L
F
G
A
S
P
A
I
S
S
S
----------------
F
L
T
S
L
P
F
E
K
T
ESG
M
Y
Y
L
P
Y
A
T
S
L
R
---------
L
S
D
L
G
Y
---
T
N
K
S
Q
S
N
L
-
G
I
T
F
N
D
L
Y
E
Y
V
A
-
G
L
K
Q
------
A
I
K
T
P
S
E
E
Y
A
K
I
G
I
-
E
K
--------------------------
D
G
K
R
L
Q
I
N
-----
S
N
V
L
-
Q
I
E
N
-------------------------
E
L
Y
A
P
I
-----
R
P
K
R
V
T
R
S
-
G
E
S
P
S
D
A
L
L
-----------------
R
GG------
I
E
--------
Y
I
E
V
R
S
-----------------------------
L
D
I
N
P
F
S
P
--
I
G
V
D
E
Q
Q
V
R
F
L
D
L
F
M
V
W
-------
C
A
L
-----------------------
A
D
A
P
E
M
--
S
S
S
E
L
A
C
T
R
V
N
W
N
R
V
I
L
E
G
R
K
-------
P
--------
G
L
T
L
G
I
G
C
E
T
A
Q
F
P
L
P
Q
V
G
K
D
L
F
R
D
L
K
R
V
-
A
Q
----------
T
L
D
S
I
N
--
G
G
E
A
Y
Q
K
V
C
D
E
L
-
V
A
C
F
D
N
P
D
L
T
F
S
A
R
I
L
R
S
M
I
D
T
T
G
K
A
F
A
E
----
A
-
Y
R
N
L
L
R
E
E
P
-
L
E
I
L
R
E
E
D
F
V
A
E
R
E
A
S
E
R
R
Q
Q
E
M
E
A
A
D
T
E
P
F
A
V
W
L
E
-----------------------
30
Fugue
69.04
10%
-98
- C5 -
1Z3I
10
?
X:
[1-644]
-------------------
L
G
L
R
R
A
--------------------
G
V
R
K
A
L
H
D
P
F
E
D
G
A
L
-
V
L
Y
E
P
P
A
I
S
A
H
D
L
I
K
A
D
--
K
E
KL
P
V
H
V
V
V
D
P
V
L
S
K
V
L
R
P
H
Q
R
E
--
G
V
K
F
L
W
D
-----
C
V
T
G
R
R
I
E
N
S
Y
G
C
I
MADEMGLGKT
L
Q
C
I
T
L
I
W
T
L
L
K
Q
S
P
D
CKP
E
I
D
K
V
I
------
V
V
S
P
S
--
S
L
V
R
--
N
W
Y
N
E
V
G
K
W
-----
L
---------
G
-----
G
----
R
V
Q
P
V
A
I
D
GGSKDEI---
D
S
K
------
L
V
N
F
I
S
Q
Q
G
M
R
-
I
P
T
P
I
L
I
I
S
Y
E
T
F
R
L
H
A
E
VLHK
G
K
------------------
V
G
L
V
I
C
D
E
G
H
RLKNSD---
N
Q
T
Y
L
A
L
N
S
M
N
A
Q
R
R
V
L
I
S
GT
P
I
Q
N
D
L
L
E
Y
F
S
L
V
H
F
V
N
S
G
I
L
G
T
A
Q
E
F
K
K
R
----------------
F
---
E
-----------
I
P
I
L
K
G
R
D
---------
A
D
A
S
D
K
D
R
A
A
G
E
Q
K
L
Q
E
-
L
I
S
I
V
N
R
C
L
I
R
R
-
T
S
D
I
------
L
S
K
Y
L
P
V
K
I
E
Q
V
V
C
-
C
N
--------------------------
L
T
P
L
Q
K
E
L
-----
Y
K
L
F
-
L
K
Q
A
-------------------------
K
P
V
E
S
L
QTGKI
S
V
S
S
L
S
S
I
-
T
S
L
K
K
L
C
N
H
-----------------
P
--------
A
L
--------
I
Y
E
K
C
L
TGEEGFDGALDLFPQNYSTKAVEPQLSGK
M
L
V
L
D
Y
I
L
--
A
M
T
R
T
T
T
S
D
K
V
V
L
V
S
N
Y
-------
T
Q
T
L
D
L
F
----
E
K
L
C
R
N
R
-
R
------
Y
L
Y
V
R
L
--
D
G
T
M
S
I
K
K
R
A
K
I
V
E
R
F
N
N
P
S
S
PEFIFML
S
S
K
A
G
G
C
--
G
L
N
L
I
G
A
N
R
L
V
M
F
D
P
D
W
N
P
A
N
D
E
Q
A
M
A
R
V
-
W
R
DGQKKTCYIY
R
L
L
S
T
G
T
I
E
E
K
I
L
Q
R
Q
A
H
K
K
-
A
L
S
S
C
V
V
D
E
E
Q
D
V
E
R
H
F
S
L
G
E
L
R
E
L
F
S
L
N
EKTL
S
-
D
T
H
D
R
F
R
C
R
-
R
C
V
N
G
R
Q
V
R
P
P
P
D
D
S
D
C
T
C
D
L
S
N
W
H
H
C
A
D
K
R
G
L
R
D
P
V
L
Q
A
SWDAAVSFVFHQRSHEDQR
32
Fugue
62.48
21%
-107
- C5 -
4QT4
-
PTH_STRPZ
A:
[1-189]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
V
K
-
M
I
V
G
------
L
G
N
P
G
S
K
Y
E
K
T
K
H
N
-
I
G
--------------------------
F
M
A
I
D
N
I
V
-----
K
N
L
D
-
V
T
F
T
-------------------------
D
D
K
-
N
F
-----
K
A
Q
I
G
S
T
F
I
N
H
E
K
V
Y
F
V
K
-----------------
P
--------
T
T
--------
F
M
N
N
S
G
-----------------------------
I
A
V
K
A
L
L
T
--
Y
Y
N
I
D
--------
I
T
D
L
-------
I
V
I
Y
D
D
L
DMEV
S
K
L
R
L
R
S
-
K
GSAGGH
N
G
I
K
S
I
--
I
A
H
I
G
T
Q
E
F
N
R
I
K
V
G
I
G
R
P
L
K
-------
G
M
T
V
I
N
H
V
M
G
Q
F
N
T
E
D
N
I
A
I
S
L
T
L
D
R
V
V
N
A
V
K
F
Y
L
Q
E
N
D
F
E
----------
K
T
M
Q
K
F
N
G
---------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
52.64
21%
-98
- C4 -
3J5Q
-
TRPV1_RAT
D:
[316-473]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
D
R
F
V
K
R
I
F
Y
F
N
F
F
V
Y
--
C
L
Y
M
I
I
F
T
A
A
A
Y
Y
R
P
V
E
G
L
P
P
Y
K
L
K
N
T
V
G
D
YFRVTGEILSVSGGVY
F
F
F
R
G
-----------
I
Q
Y
F
L
Q
R
R
---------
P
S
------
V
D
S
Y
S
E
I
L
F
-
F
V
Q
S
L
F
M
L
V
S
V
V
-
L
Y
F
S
------
Q
R
K
E
Y
V
A
S
M
V
F
S
L
A
-
M
G
--------------------------
W
T
N
M
L
Y
Y
T
-----
R
G
F
Q
-
Q
M
G
I
-------------------------
Y
A
V
M
I
E
-----
K
M
-
I
L
R
---
D
L
C
R
F
M
F
V
Y
-----------------
L
--------
V
F
--------
L
F
G
-
F
S
-----------------------------
T
A
V
V
T
L
I
E
--
D
G
K
Y
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
52.10
21%
-83
- C4 -
3J5R
-
TRPV1_RAT
B:
[316-473]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
D
R
F
V
K
R
I
F
Y
F
N
F
F
V
Y
--
C
L
Y
M
I
I
F
T
A
A
A
Y
Y
R
P
V
E
G
L
P
P
Y
K
L
K
N
T
V
G
D
YFRVTGEILSVSGGVY
F
F
F
R
G
-----------
I
Q
Y
F
L
Q
R
R
---------
P
S
------
V
D
S
Y
S
E
I
L
F
-
F
V
Q
S
L
F
M
L
V
S
V
V
-
L
Y
F
S
------
Q
R
K
E
Y
V
A
S
M
V
F
S
L
A
-
M
G
--------------------------
W
T
N
M
L
Y
Y
T
-----
R
G
F
Q
-
Q
M
G
I
-------------------------
Y
A
V
M
I
E
-----
K
M
-
I
L
R
---
D
L
C
R
F
M
F
V
Y
-----------------
L
--------
V
F
--------
L
F
G
-
F
S
-----------------------------
T
A
V
V
T
L
I
E
--
D
G
K
Y
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
50.75
21%
-100
- C4 -
3J5P
-
TRPV1_RAT
B:
[316-473]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
W
D
R
F
V
K
R
I
F
Y
F
N
F
F
V
Y
--
C
L
Y
M
I
I
F
T
A
A
A
Y
Y
R
P
V
E
G
L
P
P
Y
K
L
K
N
T
V
G
D
YFRVTGEILSVSGGVY
F
F
F
R
G
-----------
I
Q
Y
F
L
Q
R
R
---------
P
S
------
V
D
S
Y
S
E
I
L
F
-
F
V
Q
S
L
F
M
L
V
S
V
V
-
L
Y
F
S
------
Q
R
K
E
Y
V
A
S
M
V
F
S
L
A
-
M
G
--------------------------
W
T
N
M
L
Y
Y
T
-----
R
G
F
Q
-
Q
M
G
I
-------------------------
Y
A
V
M
I
E
-----
K
M
-
I
L
R
---
D
L
C
R
F
M
F
V
Y
-----------------
L
--------
V
F
--------
L
F
G
-
F
S
-----------------------------
T
A
V
V
T
L
I
E
--
D
G
K
Y
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
46.09
36%
76
- C10 -
3JAZ
-
?
A:
[103-162]
------------------------------------------------
H
V
R
S
E
D
N
T
L
R
Y
N
-
W
M
L
G
V
Y
A
R
S
T
N
Y
T
T
P
V
G
Q
L
V
V
--
N
A
P
A
I
L
N
Y
S
N
P
Q
D
A
F
N
S
V
F
V
A
L
G
I
D
Y
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
45.23
36%
81
- C10 -
3JB0
1
?
A:
[103-162]
------------------------------------------------
H
V
R
S
E
D
N
T
L
R
Y
N
-
W
M
L
G
V
Y
A
R
S
T
N
Y
T
T
P
V
G
Q
L
V
V
--
N
A
P
A
I
L
N
Y
S
N
P
Q
D
A
F
N
S
V
F
V
A
L
G
I
D
Y
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
45.05
21%
-63
- C4 -
3WAJ
2
?
A:
[107-244]
---------------------------------------------------------------------------------------------------------------------------
A
V
L
A
F
I
P
A
I
----------
G
G
V
L
A
I
L
P
V
Y
L
L
T
R
E
V
---
F
-
D
----------
K
R
A
A
--
V
I
A
A
--
F
L
I
A
I
V
P
G
Q
F
----
L
---------
Q
R
S
ILG
F
NDH
H
I
W
E
A
F
W
Q
V
----------
S
A
L
------
G
T
F
L
L
A
Y
N
R
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
44.13
36%
83
- C10 -
3JB1
-
?
A:
[103-162]
------------------------------------------------
H
V
R
S
E
D
N
T
L
R
Y
N
-
W
M
L
G
V
Y
A
R
S
T
N
Y
T
T
P
V
G
Q
L
V
V
--
N
A
P
A
I
L
N
Y
S
N
P
Q
D
A
F
N
S
V
F
V
A
L
G
I
D
Y
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
44.07
36%
86
- C10 -
3IZX
-
?
A:
[103-162]
------------------------------------------------
H
V
R
S
E
D
N
T
L
R
Y
N
-
W
M
L
G
V
Y
A
R
S
T
N
Y
T
T
P
V
G
Q
L
V
V
--
N
A
P
A
I
L
N
Y
S
N
P
Q
D
A
F
N
S
V
F
V
A
L
G
I
D
Y
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
43.78
36%
79
- C10 -
3JB3
1
?
A:
[103-162]
------------------------------------------------
H
V
R
S
E
D
N
T
L
R
Y
N
-
W
M
L
G
V
Y
A
R
S
T
N
Y
T
T
P
V
G
Q
L
V
V
--
N
A
P
A
I
L
N
Y
S
N
P
Q
D
A
F
N
S
V
F
V
A
L
G
I
D
Y
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
43.55
36%
84
- C10 -
3JB2
1
?
A:
[103-162]
------------------------------------------------
H
V
R
S
E
D
N
T
L
R
Y
N
-
W
M
L
G
V
Y
A
R
S
T
N
Y
T
T
P
V
G
Q
L
V
V
--
N
A
P
A
I
L
N
Y
S
N
P
Q
D
A
F
N
S
V
F
V
A
L
G
I
D
Y
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
43.23
36%
87
- C10 -
3JAY
1
?
A:
[103-162]
------------------------------------------------
H
V
R
S
E
D
N
T
L
R
Y
N
-
W
M
L
G
V
Y
A
R
S
T
N
Y
T
T
P
V
G
Q
L
V
V
--
N
A
P
A
I
L
N
Y
S
N
P
Q
D
A
F
N
S
V
F
V
A
L
G
I
D
Y
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
HHSearch
42.78
17%
-48
- C4 -
3RCE
2
PGLB_CAMLR
A:
[100-207]
--------------------------------------------------------------------------------------------------------------------------
E
S
I
I
L
Y
M
S
T
F
----------
F
A
S
L
I
V
V
P
I
I
L
I
A
R
E
Y
---
K
-
L
----------
T
T
Y
G
--
F
I
A
A
--
L
L
G
S
I
A
N
S
Y
-----
Y
N
R
T
MSGYYD
T
-----
D
----
M
L
V
L
V
L
P
M
----------
L
I
L
------
L
T
F
I
R
L
T
I
N
K
D
-
I
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
42.65
36%
109
- C10 -
3IZ3
-
?
A:
[103-166]
------------------------------------------------
H
V
R
S
E
D
N
T
L
R
Y
N
-
W
M
L
G
V
Y
A
R
S
T
N
Y
T
T
P
V
G
Q
L
V
V
--
N
A
P
A
I
L
N
Y
S
N
P
Q
D
A
F
N
S
V
F
V
A
L
G
I
D
Y
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
41.85
36%
104
* C10 *
3J17
-
?
A:
[103-167]
------------------------------------------------
H
V
R
S
E
D
N
T
L
R
Y
N
-
W
M
L
G
V
Y
A
R
S
T
N
Y
T
T
P
V
G
Q
L
V
V
--
N
A
P
A
I
L
N
Y
S
N
P
Q
D
A
F
N
S
V
F
V
A
L
G
I
D
Y
I
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------