@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0669: (2016-03-17 )
MMNKENPLNKYHTGKFEKQRQDYPGLQSKMTPVPDTGESSYQGANKLTGKKAFVTGGDSGIGRAAVIAYAREGADVAINYHPDEEVDAQEVKAIVEEAGQKCVLLPGDLRKEGLAKDLVKKAYNELGGLDILVLNAGLQQYQLDIQKLPAEQLRDTFEVNVFSVVFAIQEALNYLKAGASIILTSSIQGVKPSAHLVDYAMTKSSLISLTKSLAAQLGEKGIRINAVAPGPIWTALQISGGQPQDSIPEFGQDQPLGRAGQPAELASAYVLLASDEASYTTGQVYGITGGAPIN
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.....--.---.180.......190.-......200.......210.......220.......230.......---240.......250.......260.......270.......280.......290..
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MMNKENPLNKYHTG
K
F
E
K
Q
R
QDYPGLQSKMTPVPDTGESSYQGANKLTGK
K
A
F
V
TGGDSGI
G
R
A
A
V
I
AYAREG
A
D
V
A
I
N
YHPDEEV
D
A
Q
E
V
K
A
I
V
E
EAG
Q
K
C
V
LLP
G
D
L
R
K
E
G
L
A
K
D
L
V
K
K
A
Y
N
ELG
G
L
D
I
L
V
LNAG
L
Q
Q
Y
Q
L
D
I
Q
KL
P
A
E
Q
L
R
D
T
F
E
V
N
V
F
S
V
V
F
A
I
Q
E
A
L
N
Y
L
KA--G---
A
S
I
I
L
T
SSIQGVKPS-
A
H
L
V
D
Y
A
M
T
K
S
S
L
I
S
L
T
K
S
L
A
A
Q
LGEKG
I
R
I
N
A
VAPGP
I
W
T
A
L
Q
IS---GGQPQDSIPEFGQDQPLGRAGQ
P
A
E
L
A
S
A
Y
V
L
L
ASDEASYTTG
Q
V
Y
GITGGAPIN
22
PsiBlast_CBE
93.10
61%
-72
- C2 -
3R3S
3
?
C:
[3-290]
--
H
L
Y
D
P
T
T
Q
Y
Y
T
G
E
Y
P
K
Q
K
Q
P
A
P
G
V
Q
A
K
M
T
P
V
P
D
C
G
E
K
S
Y
V
G
S
G
R
L
K
D
R
K
A
L
V
T
G
G
D
S
G
I
G
R
A
A
A
I
A
Y
A
R
E
G
A
D
V
A
I
N
Y
L
P
A
E
E
E
D
A
Q
Q
V
K
A
L
I
E
E
C
G
R
K
A
V
L
L
P
G
D
L
S
D
E
S
F
A
R
S
L
V
H
K
A
R
E
A
L
G
G
L
D
I
L
A
L
V
A
G
K
Q
T
A
I
P
E
I
K
D
L
T
S
E
Q
F
Q
Q
T
F
A
V
N
V
F
A
L
F
W
I
T
Q
E
A
I
P
L
L
P
K
--
G
---
A
S
I
I
T
T
S
S
I
Q
A
Y
Q
P
S
-
P
H
L
L
D
Y
A
A
T
K
A
A
I
L
N
Y
S
R
G
L
A
K
Q
V
A
E
K
G
I
R
V
N
I
V
A
P
G
P
I
W
T
A
L
Q
I
S
---
G
G
Q
T
Q
D
K
I
P
Q
F
G
Q
Q
T
P
M
K
R
A
G
Q
P
A
E
L
A
P
V
Y
V
Y
L
A
S
Q
E
S
S
Y
V
T
A
E
V
H
G
V
C
G
G
----
23
PsiBlast_CBE
92.80
61%
-71
- C2 -
3R3S
4
?
B:
[3-290]
--
H
L
Y
D
P
T
T
Q
Y
Y
T
G
E
Y
P
K
Q
K
Q
P
A
P
G
V
Q
A
K
M
T
P
V
P
D
C
G
E
K
S
Y
V
G
S
G
R
L
K
D
R
K
A
L
V
T
G
G
D
S
G
I
G
R
A
A
A
I
A
Y
A
R
E
G
A
D
V
A
I
N
Y
L
P
A
E
E
E
D
A
Q
Q
V
K
A
L
I
E
E
C
G
R
K
A
V
L
L
P
G
D
L
S
D
E
S
F
A
R
S
L
V
H
K
A
R
E
A
L
G
G
L
D
I
L
A
L
V
A
G
K
Q
T
A
I
P
E
I
K
D
L
T
S
E
Q
F
Q
Q
T
F
A
V
N
V
F
A
L
F
W
I
T
Q
E
A
I
P
L
L
P
K
--
G
---
A
S
I
I
T
T
S
S
I
Q
A
Y
Q
P
S
-
P
H
L
L
D
Y
A
A
T
K
A
A
I
L
N
Y
S
R
G
L
A
K
Q
V
A
E
K
G
I
R
V
N
I
V
A
P
G
P
I
W
T
A
L
Q
I
S
---
G
G
Q
T
Q
D
K
I
P
Q
F
G
Q
Q
T
P
M
K
R
A
G
Q
P
A
E
L
A
P
V
Y
V
Y
L
A
S
Q
E
S
S
Y
V
T
A
E
V
H
G
V
C
G
G
----
114
HHSearch
92.44
60%
-72
- C2 -
3R3S
3
?
A:
[3-293]
--
H
L
Y
D
P
T
T
Q
Y
Y
T
G
E
Y
P
K
Q
K
Q
P
A
P
G
V
Q
A
K
M
T
P
V
P
D
C
G
E
K
S
Y
V
G
S
G
R
L
K
D
R
K
A
L
V
T
G
G
D
S
G
I
G
R
A
A
A
I
A
Y
A
R
E
G
A
D
V
A
I
N
Y
L
P
A
E
E
E
D
A
Q
Q
V
K
A
L
I
E
E
C
G
R
K
A
V
L
L
P
G
D
L
S
D
E
S
F
A
R
S
L
V
H
K
A
R
E
A
L
G
G
L
D
I
L
A
L
V
A
G
K
Q
T
A
I
P
E
I
K
D
L
T
S
E
Q
F
Q
Q
T
F
A
V
N
V
F
A
L
F
W
I
T
Q
E
A
I
P
L
L
P
K
--
G
---
A
S
I
I
T
T
S
S
I
Q
A
Y
Q
P
S
-
P
H
L
L
D
Y
A
A
T
K
A
A
I
L
N
Y
S
R
G
L
A
K
Q
V
A
E
K
G
I
R
V
N
I
V
A
P
G
P
I
W
T
A
L
Q
I
S
---
G
G
Q
T
Q
D
K
I
P
Q
F
G
Q
Q
T
P
M
K
R
A
G
Q
P
A
E
L
A
P
V
Y
V
Y
L
A
S
Q
E
S
S
Y
V
T
A
E
V
H
G
V
C
G
G
E
H
L
-
21
PsiBlast_CBE
91.76
61%
-70
- C2 -
3R3S
3
?
D:
[3-290]
--
H
L
Y
D
P
T
T
Q
Y
Y
T
G
E
Y
P
K
Q
K
Q
P
A
P
G
V
Q
A
K
M
T
P
V
P
D
C
G
E
K
S
Y
V
G
S
G
R
L
K
D
R
K
A
L
V
T
G
G
D
S
G
I
G
R
A
A
A
I
A
Y
A
R
E
G
A
D
V
A
I
N
Y
L
P
A
E
E
E
D
A
Q
Q
V
K
A
L
I
E
E
C
G
R
K
A
V
L
L
P
G
D
L
S
D
E
S
F
A
R
S
L
V
H
K
A
R
E
A
L
G
G
L
D
I
L
A
L
V
A
G
K
Q
T
A
I
P
E
I
K
D
L
T
S
E
Q
F
Q
Q
T
F
A
V
N
V
F
A
L
F
W
I
T
Q
E
A
I
P
L
L
P
K
--
G
---
A
S
I
I
T
T
S
S
I
Q
A
Y
Q
P
S
-
P
H
L
L
D
Y
A
A
T
K
A
A
I
L
N
Y
S
R
G
L
A
K
Q
V
A
E
K
G
I
R
V
N
I
V
A
P
G
P
I
W
T
A
L
Q
I
S
---
G
G
Q
T
Q
D
K
I
P
Q
F
G
Q
Q
T
P
M
K
R
A
G
Q
P
A
E
L
A
P
V
Y
V
Y
L
A
S
Q
E
S
S
Y
V
T
A
E
V
H
G
V
C
G
G
----
1
PsiBlast_PDB
91.54
61%
-70
- C2 -
3R3S
3
?
A:
[3-290]
--
H
L
Y
D
P
T
T
Q
Y
Y
T
G
E
Y
P
K
Q
K
Q
P
A
P
G
V
Q
A
K
M
T
P
V
P
D
C
G
E
K
S
Y
V
G
S
G
R
L
K
D
R
K
A
L
V
T
G
G
D
S
G
I
G
R
A
A
A
I
A
Y
A
R
E
G
A
D
V
A
I
N
Y
L
P
A
E
E
E
D
A
Q
Q
V
K
A
L
I
E
E
C
G
R
K
A
V
L
L
P
G
D
L
S
D
E
S
F
A
R
S
L
V
H
K
A
R
E
A
L
G
G
L
D
I
L
A
L
V
A
G
K
Q
T
A
I
P
E
I
K
D
L
T
S
E
Q
F
Q
Q
T
F
A
V
N
V
F
A
L
F
W
I
T
Q
E
A
I
P
L
L
P
K
--
G
---
A
S
I
I
T
T
S
S
I
Q
A
Y
Q
P
S
-
P
H
L
L
D
Y
A
A
T
K
A
A
I
L
N
Y
S
R
G
L
A
K
Q
V
A
E
K
G
I
R
V
N
I
V
A
P
G
P
I
W
T
A
L
Q
I
S
---
G
G
Q
T
Q
D
K
I
P
Q
F
G
Q
Q
T
P
M
K
R
A
G
Q
P
A
E
L
A
P
V
Y
V
Y
L
A
S
Q
E
S
S
Y
V
T
A
E
V
H
G
V
C
G
G
----
29
PsiBlast_CBE
84.13
47%
-76
- C2 -
3I3O
3
?
C:
[22-290]
-----------------------
P
G
I
E
S
L
M
N
P
L
P
Q
F
E
D
P
N
Y
K
G
S
E
K
L
K
G
K
N
V
L
I
T
G
G
D
S
G
I
G
R
A
V
S
I
A
F
A
K
E
G
A
N
I
A
I
A
Y
L
-
D
E
E
G
D
A
N
E
T
K
Q
Y
V
E
K
E
G
V
K
C
V
L
L
P
G
D
L
S
D
E
Q
H
C
K
D
I
V
Q
E
T
V
R
Q
L
G
S
L
N
I
L
V
N
N
V
A
Q
Q
Y
P
Q
Q
G
L
E
Y
I
T
A
E
Q
L
E
K
T
F
R
I
N
I
F
S
Y
F
H
V
T
K
A
A
L
S
H
L
K
Q
--
G
---
D
V
I
I
N
T
A
S
I
V
A
Y
E
G
N
-
E
T
L
I
D
Y
S
A
T
K
G
A
I
V
A
F
T
R
S
L
S
Q
S
L
V
Q
K
G
I
R
V
N
G
V
A
P
G
P
I
W
T
P
L
-
I
P
---
S
S
F
D
E
K
K
V
S
Q
F
G
S
N
V
P
M
Q
R
P
G
Q
P
Y
E
L
A
P
A
Y
V
Y
L
A
S
S
D
S
S
Y
V
T
G
Q
M
I
H
V
N
G
G
V
I
V
N
28
PsiBlast_CBE
83.90
47%
-74
- C2 -
3I3O
5
?
D:
[22-290]
-----------------------
P
G
I
E
S
L
M
N
P
L
P
Q
F
E
D
P
N
Y
K
G
S
E
K
L
K
G
K
N
V
L
I
T
G
G
D
S
G
I
G
R
A
V
S
I
A
F
A
K
E
G
A
N
I
A
I
A
Y
L
-
D
E
E
G
D
A
N
E
T
K
Q
Y
V
E
K
E
G
V
K
C
V
L
L
P
G
D
L
S
D
E
Q
H
C
K
D
I
V
Q
E
T
V
R
Q
L
G
S
L
N
I
L
V
N
N
V
A
Q
Q
Y
P
Q
Q
G
L
E
Y
I
T
A
E
Q
L
E
K
T
F
R
I
N
I
F
S
Y
F
H
V
T
K
A
A
L
S
H
L
K
Q
--
G
---
D
V
I
I
N
T
A
S
I
V
A
Y
E
G
N
-
E
T
L
I
D
Y
S
A
T
K
G
A
I
V
A
F
T
R
S
L
S
Q
S
L
V
Q
K
G
I
R
V
N
G
V
A
P
G
P
I
W
T
P
L
-
I
P
---
S
S
F
D
E
K
K
V
S
Q
F
G
S
N
V
P
M
Q
R
P
G
Q
P
Y
E
L
A
P
A
Y
V
Y
L
A
S
S
D
S
S
Y
V
T
G
Q
M
I
H
V
N
G
G
V
I
V
N
30
PsiBlast_CBE
83.87
47%
-76
- C2 -
3I3O
5
?
B:
[22-290]
-----------------------
P
G
I
E
S
L
M
N
P
L
P
Q
F
E
D
P
N
Y
K
G
S
E
K
L
K
G
K
N
V
L
I
T
G
G
D
S
G
I
G
R
A
V
S
I
A
F
A
K
E
G
A
N
I
A
I
A
Y
L
-
D
E
E
G
D
A
N
E
T
K
Q
Y
V
E
K
E
G
V
K
C
V
L
L
P
G
D
L
S
D
E
Q
H
C
K
D
I
V
Q
E
T
V
R
Q
L
G
S
L
N
I
L
V
N
N
V
A
Q
Q
Y
P
Q
Q
G
L
E
Y
I
T
A
E
Q
L
E
K
T
F
R
I
N
I
F
S
Y
F
H
V
T
K
A
A
L
S
H
L
K
Q
--
G
---
D
V
I
I
N
T
A
S
I
V
A
Y
E
G
N
-
E
T
L
I
D
Y
S
A
T
K
G
A
I
V
A
F
T
R
S
L
S
Q
S
L
V
Q
K
G
I
R
V
N
G
V
A
P
G
P
I
W
T
P
L
-
I
P
---
S
S
F
D
E
K
K
V
S
Q
F
G
S
N
V
P
M
Q
R
P
G
Q
P
Y
E
L
A
P
A
Y
V
Y
L
A
S
S
D
S
S
Y
V
T
G
Q
M
I
H
V
N
G
G
V
I
V
N
3
PsiBlast_PDB
83.77
47%
-77
- C2 -
3IJR
5
?
A:
[22-290]
-----------------------
P
G
I
E
S
L
M
N
P
L
P
Q
F
E
D
P
N
Y
K
G
S
E
K
L
K
G
K
N
V
L
I
T
G
G
D
S
G
I
G
R
A
V
S
I
A
F
A
K
E
G
A
N
I
A
I
A
Y
L
-
D
E
E
G
D
A
N
E
T
K
Q
Y
V
E
K
E
G
V
K
C
V
L
L
P
G
D
L
S
D
E
Q
H
C
K
D
I
V
Q
E
T
V
R
Q
L
G
S
L
N
I
L
V
N
N
V
A
Q
Q
Y
P
Q
Q
G
L
E
Y
I
T
A
E
Q
L
E
K
T
F
R
I
N
I
F
S
Y
F
H
V
T
K
A
A
L
S
H
L
K
Q
--
G
---
D
V
I
I
N
T
A
S
I
V
A
Y
E
G
N
-
E
T
L
I
D
Y
S
A
T
K
G
A
I
V
A
F
T
R
S
L
S
Q
S
L
V
Q
K
G
I
R
V
N
G
V
A
P
G
P
I
W
T
P
L
-
I
P
---
S
S
F
D
E
K
K
V
S
Q
F
G
S
N
V
P
M
Q
R
P
G
Q
P
Y
E
L
A
P
A
Y
V
Y
L
A
S
S
D
S
S
Y
V
T
G
Q
M
I
H
V
N
G
G
V
I
V
N
27
PsiBlast_CBE
83.71
47%
-74
- C2 -
3I3O
3
?
E:
[22-290]
-----------------------
P
G
I
E
S
L
M
N
P
L
P
Q
F
E
D
P
N
Y
K
G
S
E
K
L
K
G
K
N
V
L
I
T
G
G
D
S
G
I
G
R
A
V
S
I
A
F
A
K
E
G
A
N
I
A
I
A
Y
L
-
D
E
E
G
D
A
N
E
T
K
Q
Y
V
E
K
E
G
V
K
C
V
L
L
P
G
D
L
S
D
E
Q
H
C
K
D
I
V
Q
E
T
V
R
Q
L
G
S
L
N
I
L
V
N
N
V
A
Q
Q
Y
P
Q
Q
G
L
E
Y
I
T
A
E
Q
L
E
K
T
F
R
I
N
I
F
S
Y
F
H
V
T
K
A
A
L
S
H
L
K
Q
--
G
---
D
V
I
I
N
T
A
S
I
V
A
Y
E
G
N
-
E
T
L
I
D
Y
S
A
T
K
G
A
I
V
A
F
T
R
S
L
S
Q
S
L
V
Q
K
G
I
R
V
N
G
V
A
P
G
P
I
W
T
P
L
-
I
P
---
S
S
F
D
E
K
K
V
S
Q
F
G
S
N
V
P
M
Q
R
P
G
Q
P
Y
E
L
A
P
A
Y
V
Y
L
A
S
S
D
S
S
Y
V
T
G
Q
M
I
H
V
N
G
G
V
I
V
N
26
PsiBlast_CBE
83.38
47%
-76
- C2 -
3I3O
1
?
F:
[22-290]
-----------------------
P
G
I
E
S
L
M
N
P
L
P
Q
F
E
D
P
N
Y
K
G
S
E
K
L
K
G
K
N
V
L
I
T
G
G
D
S
G
I
G
R
A
V
S
I
A
F
A
K
E
G
A
N
I
A
I
A
Y
L
-
D
E
E
G
D
A
N
E
T
K
Q
Y
V
E
K
E
G
V
K
C
V
L
L
P
G
D
L
S
D
E
Q
H
C
K
D
I
V
Q
E
T
V
R
Q
L
G
S
L
N
I
L
V
N
N
V
A
Q
Q
Y
P
Q
Q
G
L
E
Y
I
T
A
E
Q
L
E
K
T
F
R
I
N
I
F
S
Y
F
H
V
T
K
A
A
L
S
H
L
K
Q
--
G
---
D
V
I
I
N
T
A
S
I
V
A
Y
E
G
N
-
E
T
L
I
D
Y
S
A
T
K
G
A
I
V
A
F
T
R
S
L
S
Q
S
L
V
Q
K
G
I
R
V
N
G
V
A
P
G
P
I
W
T
P
L
-
I
P
---
S
S
F
D
E
K
K
V
S
Q
F
G
S
N
V
P
M
Q
R
P
G
Q
P
Y
E
L
A
P
A
Y
V
Y
L
A
S
S
D
S
S
Y
V
T
G
Q
M
I
H
V
N
G
G
V
I
V
N
2
PsiBlast_PDB
83.34
47%
-75
- C2 -
3I3O
5
?
A:
[22-290]
-----------------------
P
G
I
E
S
L
M
N
P
L
P
Q
F
E
D
P
N
Y
K
G
S
E
K
L
K
G
K
N
V
L
I
T
G
G
D
S
G
I
G
R
A
V
S
I
A
F
A
K
E
G
A
N
I
A
I
A
Y
L
-
D
E
E
G
D
A
N
E
T
K
Q
Y
V
E
K
E
G
V
K
C
V
L
L
P
G
D
L
S
D
E
Q
H
C
K
D
I
V
Q
E
T
V
R
Q
L
G
S
L
N
I
L
V
N
N
V
A
Q
Q
Y
P
Q
Q
G
L
E
Y
I
T
A
E
Q
L
E
K
T
F
R
I
N
I
F
S
Y
F
H
V
T
K
A
A
L
S
H
L
K
Q
--
G
---
D
V
I
I
N
T
A
S
I
V
A
Y
E
G
N
-
E
T
L
I
D
Y
S
A
T
K
G
A
I
V
A
F
T
R
S
L
S
Q
S
L
V
Q
K
G
I
R
V
N
G
V
A
P
G
P
I
W
T
P
L
-
I
P
---
S
S
F
D
E
K
K
V
S
Q
F
G
S
N
V
P
M
Q
R
P
G
Q
P
Y
E
L
A
P
A
Y
V
Y
L
A
S
S
D
S
S
Y
V
T
G
Q
M
I
H
V
N
G
G
V
I
V
N
24
PsiBlast_CBE
82.73
47%
-77
- C2 -
3I3O
6
?
H:
[22-290]
-----------------------
P
G
I
E
S
L
M
N
P
L
P
Q
F
E
D
P
N
Y
K
G
S
E
K
L
K
G
K
N
V
L
I
T
G
G
D
S
G
I
G
R
A
V
S
I
A
F
A
K
E
G
A
N
I
A
I
A
Y
L
-
D
E
E
G
D
A
N
E
T
K
Q
Y
V
E
K
E
G
V
K
C
V
L
L
P
G
D
L
S
D
E
Q
H
C
K
D
I
V
Q
E
T
V
R
Q
L
G
S
L
N
I
L
V
N
N
V
A
Q
Q
Y
P
Q
Q
G
L
E
Y
I
T
A
E
Q
L
E
K
T
F
R
I
N
I
F
S
Y
F
H
V
T
K
A
A
L
S
H
L
K
Q
--
G
---
D
V
I
I
N
T
A
S
I
V
A
Y
E
G
N
-
E
T
L
I
D
Y
S
A
T
K
G
A
I
V
A
F
T
R
S
L
S
Q
S
L
V
Q
K
G
I
R
V
N
G
V
A
P
G
P
I
W
T
P
L
-
I
P
---
S
S
F
-----
S
Q
F
G
S
N
V
P
M
Q
R
P
G
Q
P
Y
E
L
A
P
A
Y
V
Y
L
A
S
S
D
S
S
Y
V
T
G
Q
M
I
H
V
N
G
G
V
I
V
N
13
PsiBlast_PDB
76.15
31%
-85
- C2 -
3AY6
2
DHG4_BACME
A:
[13-257]
----------------------------------------------
L
K
D
K
V
V
V
I
T
G
G
S
T
G
L
G
R
A
M
A
V
R
F
G
Q
E
E
A
K
V
V
I
N
Y
Y
N
N
E
E
-
E
A
L
D
A
K
K
E
V
E
E
A
G
G
Q
A
I
I
V
Q
G
D
V
T
K
E
E
D
V
V
N
L
V
Q
T
A
I
K
E
F
G
T
L
D
V
M
I
N
N
A
G
V
E
N
-
P
V
P
S
H
E
L
S
L
D
N
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
--
N
DIK
G
N
V
I
N
M
S
S
V
H
E
M
I
P
W
-
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
M
N
T
P
I
N
A
E
---
K
F
A
D
P
V
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
K
P
E
E
V
A
A
V
A
A
F
L
A
S
S
Q
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
----
55
PsiBlast_CBE
76.01
31%
-85
- C2 -
3AY6
2
DHG4_BACME
C:
[13-257]
----------------------------------------------
L
K
D
K
V
V
V
I
T
G
G
S
T
G
L
G
R
A
M
A
V
R
F
G
Q
E
E
A
K
V
V
I
N
Y
Y
N
N
E
E
-
E
A
L
D
A
K
K
E
V
E
E
A
G
G
Q
A
I
I
V
Q
G
D
V
T
K
E
E
D
V
V
N
L
V
Q
T
A
I
K
E
F
G
T
L
D
V
M
I
N
N
A
G
V
E
N
-
P
V
P
S
H
E
L
S
L
D
N
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
--
N
DIK
G
N
V
I
N
M
S
S
V
H
E
M
I
P
W
-
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
M
N
T
P
I
N
A
E
---
K
F
A
D
P
V
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
K
P
E
E
V
A
A
V
A
A
F
L
A
S
S
Q
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
----
16
PsiBlast_PDB
75.79
31%
-86
- C2 -
3AUU
1
DHG4_BACME
A:
[13-257]
----------------------------------------------
L
K
D
K
V
V
V
I
T
G
G
S
T
G
L
G
R
A
M
A
V
R
F
G
Q
E
E
A
K
V
V
I
N
Y
Y
N
N
E
E
-
E
A
L
D
A
K
K
E
V
E
E
A
G
G
Q
A
I
I
V
Q
G
D
V
T
K
E
E
D
V
V
N
L
V
Q
T
A
I
K
E
F
G
T
L
D
V
M
I
N
N
A
G
V
E
N
-
P
V
P
S
H
E
L
S
L
D
N
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
--
N
DIK
G
N
V
I
N
M
S
S
V
H
E
M
I
P
W
-
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
M
N
T
P
I
N
A
E
---
K
F
A
D
P
V
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
K
P
E
E
V
A
A
V
A
A
F
L
A
S
S
Q
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
----
14
PsiBlast_PDB
75.72
31%
-84
- C2 -
3AUS
-
DHG4_BACME
A:
[5-249]
----------------------------------------------
L
K
D
K
V
V
V
I
T
G
G
S
T
G
L
G
R
A
M
A
V
R
F
G
Q
E
E
A
K
V
V
I
N
Y
Y
N
N
E
E
-
E
A
L
D
A
K
K
E
V
E
E
A
G
G
Q
A
I
I
V
Q
G
D
V
T
K
E
E
D
V
V
N
L
V
Q
T
A
I
K
E
F
G
T
L
D
V
M
I
N
N
A
G
V
E
N
-
P
V
P
S
H
E
L
S
L
D
N
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
--
N
DIK
G
N
V
I
N
M
S
S
V
H
E
M
I
P
W
-
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
M
N
T
P
I
N
A
E
---
K
F
A
D
P
V
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
K
P
E
E
V
A
A
V
A
A
F
L
A
S
S
Q
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
----
58
PsiBlast_CBE
75.57
31%
-87
- C2 -
3AUT
1
DHG4_BACME
B:
[13-257]
----------------------------------------------
L
K
D
K
V
V
V
I
T
G
G
S
T
G
L
G
R
A
M
A
V
R
F
G
Q
E
E
A
K
V
V
I
N
Y
Y
N
N
E
E
-
E
A
L
D
A
K
K
E
V
E
E
A
G
G
Q
A
I
I
V
Q
G
D
V
T
K
E
E
D
V
V
N
L
V
Q
T
A
I
K
E
F
G
T
L
D
V
M
I
N
N
A
G
V
E
N
-
P
V
P
S
H
E
L
S
L
D
N
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
--
N
DIK
G
N
V
I
N
M
S
S
V
H
E
M
I
P
W
-
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
M
N
T
P
I
N
A
E
---
K
F
A
D
P
V
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
K
P
E
E
V
A
A
V
A
A
F
L
A
S
S
Q
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
----
15
PsiBlast_PDB
75.16
31%
-82
- C2 -
3AUT
-
DHG4_BACME
A:
[13-257]
----------------------------------------------
L
K
D
K
V
V
V
I
T
G
G
S
T
G
L
G
R
A
M
A
V
R
F
G
Q
E
E
A
K
V
V
I
N
Y
Y
N
N
E
E
-
E
A
L
D
A
K
K
E
V
E
E
A
G
G
Q
A
I
I
V
Q
G
D
V
T
K
E
E
D
V
V
N
L
V
Q
T
A
I
K
E
F
G
T
L
D
V
M
I
N
N
A
G
V
E
N
-
P
V
P
S
H
E
L
S
L
D
N
W
N
K
V
I
D
T
N
L
T
G
A
F
L
G
S
R
E
A
I
K
Y
F
V
E
--
N
DIK
G
N
V
I
N
M
S
S
V
H
E
M
I
P
W
-
P
L
F
V
H
Y
A
A
S
K
G
G
M
K
L
M
T
E
T
L
A
L
E
Y
A
P
K
G
I
R
V
N
N
I
G
P
G
A
M
N
T
P
I
N
A
E
---
K
F
A
D
P
V
Q
R
A
D
V
E
S
M
I
P
M
G
Y
I
G
K
P
E
E
V
A
A
V
A
A
F
L
A
S
S
Q
A
S
Y
V
T
G
I
T
L
F
A
D
G
G
----
97
PsiBlast_CBE
74.72
35%
-76
- C2 -
3TOX
1
?
E:
[4-256]
--------------------------------------------
S
R
L
E
G
K
I
A
I
V
T
G
A
S
S
G
I
G
R
A
A
A
L
L
F
A
R
E
G
A
K
V
V
V
T
A
R
N
G
N
A
L
--
A
E
L
T
D
E
I
A
G
G
G
G
E
A
A
A
L
A
G
D
V
G
D
E
A
L
H
E
A
L
V
E
L
A
V
R
R
F
G
G
L
D
T
A
F
N
N
A
G
A
L
G
A
M
G
E
I
S
S
L
S
V
E
G
W
R
E
T
L
D
T
N
L
T
S
A
F
L
A
A
K
Y
Q
V
P
A
I
A
A
LG
G
---
G
S
L
T
F
T
S
S
F
V
G
H
T
A
G
F
A
G
V
A
P
Y
A
A
S
K
A
G
L
I
G
L
V
Q
A
L
A
V
E
L
G
A
R
G
I
R
V
N
A
L
L
P
G
G
T
D
T
P
A
N
F
A
NLP
G
A
A
P
E
T
R
G
F
V
E
G
L
-
H
A
L
K
R
I
A
R
P
E
E
I
A
E
A
A
L
Y
L
A
S
D
G
A
S
F
V
T
G
A
A
L
L
A
D
G
G
A
S
V
T