@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0724: (2016-03-18 )
MRIWIKSLLVITACIFSLTLLNTKYTFYSPTVKLESAKVVYKLNNEPFNVRLDVPLVNQMDAPTLFNGCEVTSLAMLLQFNGKRVTKNELANNLSTTPIEQNGLHGNPDKAFVGSISGDSPGLGVNHAPIAKLAAKYVNEAHVHDISGNSIQDIITVLSTGAPVWIITTTDYHAPKNWQTVQTKEGKKKITYSMHSVIITGFDKNNFYINDPYGHKNRAVKRSVLEEGWSAMGKQAIYLSRP
Atome Classification :
(20 SA)
--------------------------.........10........20..-.-.....30........40.---.......50.....-.-..----60.........70....-------------....80.-----..--.--..-----...90........100..-.....110---......-...-120-.........130.....-.--.140..--.-....150----........-160-.-......170--....---.--..-.180..---------.--.----.-..190---.......200..----.---------.---...-----210--...-..-----.-----...220.......230-..------...-.-.240-----
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--------------------------MR
I
W
I
K
S
L
L
V
I
T
A
C
I
F
S
L
T
L
LNT-
K
-
Y
T
F
YS
P
T
V
K
L
ES
A
K
V
V
Y
K
---LNNE
P
F
N
V
R
LDVPL-V-NQ----M-DAPTLFNG
C
E
V
T
S
L
A
-------------
M
L
L
QF-N-----GK--R--V
T
-----
K
N
E
L
ANNLSTTPIEQNGL-HGNPDK-----
A
F
V
GSI-SGD-S---PGLGVN
H
A
P
I
A
K
L
A
A
K
Y
-
V
--
N
EA
H
V
H--D-ISG
N
S
-
I
----
Q
D
I
I
T
V
LS-TGA-
P
-
V
W
I
I
TTTD---YHAP---K--N
W
-
Q
T
VQTK---------E--G----K-
K
K
I
T
Y
---
S
M
H
S
V
I
I
T
G
FDK----N---------
N
---
F
Y
I-----N----DPY-GH-----K-----
N
R
A
V
K
R
S
V
L
E
E
G
W
S
AM-GK------
Q
A
I
-Y-LSRP-----
44
Fugue
96.39
37%
-91
- C6 -
3ERV
2
?
A:
[29-228]
----------------------------------------------------------------------------
D
E
K
V
I
L
S
N
V
P
F
-
I
-
Q
Q
----
L
---
P
E
L
D
R
G
C
E
V
T
S
L
A
-------------
M
M
L
Q
Y
-
A
-----
G
I
--
T
--
V
D
-----
K
M
K
L
A
N
E
I
K
K
V
D
F
M
N
D
G
V
-
R
G
N
P
N
E
-----
G
F
V
G
N
I
Y
T
F
S
-
E
---
S
G
Y
G
V
Y
H
G
P
L
F
Q
L
A
K
K
Y
-
L
--
P
N
-
K
A
V
--
D
-
L
T
G
K
S
-
I
----
E
E
L
Y
K
S
V
K
-
A
G
Q
-
P
-
V
V
I
I
T
N
A
T
---
F
A
P
L
DE-
D
--
E
F
-
T
T
W
E
T
N
---------
N
--
G
----
D
-
V
S
I
T
Y
---
N
E
H
C
V
V
L
I
G
Y
D
Q
----
E
---------
S
---
V
Y
I
-----
R
----
D
P
L
K
D
S
-----
L
-----
D
V
K
V
P
R
E
K
F
E
Q
A
W
V
Q
M
-
G
S
------
Q
A
I
-
S
-
Y
V
K
R
SK---
1
PsiBlast_PDB
94.07
37%
-90
- C6 -
3ERV
2
?
A:
[29-226]
----------------------------------------------------------------------------
D
E
K
V
I
L
S
N
V
P
F
-
I
-
Q
Q
----
L
---
P
E
L
D
R
G
C
E
V
T
S
L
A
-------------
M
M
L
Q
Y
-
A
-----
G
I
--
T
--
V
D
-----
K
M
K
L
A
N
E
I
K
K
V
D
F
M
N
D
G
V
-
R
G
N
P
N
E
-----
G
F
V
G
N
I
Y
T
F
S
-
E
---
S
G
Y
G
V
Y
H
G
P
L
F
Q
L
A
K
K
Y
-
L
--
P
N
K
A
V
---
D
-
L
T
G
K
S
-
I
----
E
E
L
Y
K
S
V
K
-
A
G
Q
-
P
-
V
V
I
I
T
N
A
T
---
F
-
A
P
LDE
D
--
E
F
-
T
T
W
E
T
N
---------
N
--
G
----
D
-
V
S
I
T
Y
---
N
E
H
C
V
V
L
I
G
Y
D
Q
----
E
---------
S
---
V
Y
I
-----
R
----
D
P
L
-
K
D
-----
S
L----
D
V
K
V
P
R
E
K
F
E
Q
A
W
V
Q
M
-
G
S
------
Q
A
I
S
Y
-
V
K
R
------
21
HHSearch
93.73
38%
-89
* C6 *
3ERV
2
?
A:
[29-226]
----------------------------------------------------------------------------
D
E
K
V
I
L
S
N
V
P
F
-
I
-
Q
Q
----
L
---
P
E
L
D
R
G
C
E
V
T
S
L
A
-------------
M
M
L
Q
Y
-
A
-----
G
I
--
T
--
V
D
-----
K
M
K
L
A
N
E
I
K
K
V
D
F
M
N
D
G
V
-
R
G
N
P
N
E
-----
G
F
V
G
N
I
-
Y
T
F
S
E
---
S
G
Y
G
V
Y
H
G
P
L
F
Q
L
A
K
K
Y
L
P
--
N
--
K
A
V
--
D
-
L
T
G
K
S
-
I
----
E
E
L
Y
K
S
V
K
-
A
G
Q
-
P
-
V
V
I
I
T
N
A
T
---
F
A
P
L
---
D
ED
E
F
-
T
T
W
E
T
N
---------
N
--
G
----
D
-
V
S
I
T
Y
---
N
E
H
C
V
V
L
I
G
Y
D
Q
----
E
---------
S
---
V
Y
I
-----
R
----
D
P
L
-
K
D
-----
S
L----
D
V
K
V
P
R
E
K
F
E
Q
A
W
V
Q
M
-
G
S
------
Q
A
I
-
S
-
Y
V
K
R
-----
23
HHSearch
62.00
20%
-80
- C6 -
3K8U
-
?
A:
[5-132]
-----------------------------------------------------------------------------------
H
Y
K
L
-
V
-
P
Q
----
I
-
D
----
T
R
D
C
G
P
A
V
L
A
-------------
S
V
A
K
H
-
Y
-----
G
S
--
N
--
Y
S
-----
I
A
Y
L
R
E
L
S
K
T
N
K
---------------------------------
Q
--
G
T
T
A
L
G
I
V
E
A
A
K
K
L
-
G
--
F
E
--
T
R
--
S
-
I
K
-
A
D
-
M
----
T
L
F
-
D
Y
N
D
-
L
T
Y
-
P
-
F
I
V
H
V
I
K
G
--------------------------------------------
K
R
---
L
Q
H
Y
Y
V
V
Y
G
S
Q
N
----
N
---------
Q
---
L
I
I
-----
G
----
D
P
D
-
P
S
V----
K
-----
V
T
R
M
S
K
E
R
F
Q
S
E
W
T
--------------------------
26
HHSearch
60.59
19%
-90
- C6 -
2BU3
3
?
A:
[77-232]
------------------------------------------------------------------------------------------------------
N
Q
A
Y
C
G
V
A
S
I
I
-------------
M
V
L
N
S
-
L
-----
G
I
--
N
--
A
-Y
R
V
F
T
Q
D
N
F
F
S
---
T
K
A
V
--------
I
A
P
------
E
V
---------
V
---
A
R
Q
G
M
T
L
D
E
L
G
R
L
I
A
S
Y
-
G
--
V
K
V
K
V
N
--
H
-
A
S
D
T
N
-
I
E
D
F
R
K
Q
V
A
E
N
L
K
Q
D
G
N
-
F
-
V
I
V
N
Y
L
R
K
---
E
I
G
-------------------------------------
Q
E
R
---
G
G
H
I
S
P
L
A
A
Y
N
E
QT--
D
---------
R
---
F
L
I
-----
M
----
D
V
S
-
R
Y
KY---
P
-----
P
V
W
V
K
T
T
D
L
W
K
A
M
---------------------------
45
Fugue
48.27
13%
-53
- C6 -
3K8U
-
?
A:
[5-141]
-----------------------------------------------------------------------------------
H
Y
K
L
-
V
-
P
Q
----
I
-
D
T
R
D
----
C
G
P
A
V
L
A
-------------
S
V
A
K
H
-
Y
-----
G
S
--
N
--
Y
S
-----
I
A
Y
L
R
E
L
S
K
T
N
K
---
Q
G
T
-
T
A
L
G
I
V
-----
E
A
A
K
K
L
-
G
F
E
-
T
---
R
S
I
K
A
D
M
T
L
F
D
Y
N
D
L
T
Y
-
P
--
F
I
V
H
V
I
--
K
---
G
K
R
-
L
----
Q
H
Y
Y
V
V
Y
G
-
S
Q
N
-
N
---
Q
L
I
I
G
D
---
P
D
P
S
---
V
--
K
V
-
T
R
M
S
K
E
---------
R
--
F
----
Q
-
S
E
W
T
G
---
L
A
I
F
L
A
P
Q
--------------------------------------------------------------------------------------------
25
HHSearch
47.82
11%
-67
- C6 -
1X9Y
-
SSPB_STAAU
A:
[228-365]
---------------------------------------------------------------------------------
L
K
N
F
K
I
R
E
-
Q
Q
----
F
-
D
----
N
S
W
C
A
G
F
S
M
A
-------------
A
L
L
N
A
-
T
-----
K
N
--
T
DT
Y
N
-----
A
H
D
I
M
R
T
L
Y
P
E
V
-------
S
E
Q
D
--------
L
P
N
-----------
C
--
A
T
F
P
N
Q
M
I
E
Y
G
K
S
Q
-
G
--
R
D
I
H
-
Y
--
Q
-
E
G
V
P
S
-
Y
----
N
Q
V
D
Q
L
T
K
-
D
N
V
-
G
-
I
M
I
L
A
Q
--------------------
S
V
S
Q
---------
N
---------
P
N
D
P
H
---
L
G
H
A
L
A
V
V
G
N
A
K
I
ND
Q
E
---------
K
---
L
I
Y
-----
W
----
N
P
W
-
D
T
-----
E
---------------------------------------------
43
HHSearch
47.21
18%
-108
- C6 -
2BDZ
1
MEX1_JACME
A:
[117-179]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
-
E
----
I
S
L
I
Q
A
I
A
-
N
-
Q
-
P
-
V
S
V
V
T
D
S
R
---
G
R
G
--------
F
-
Q
F
Y
K
G
G
---------
I
Y-
E
----
G
-
P
C
G
T
N
---
T
D
H
A
V
T
A
V
G
Y
G
K
----
T
---------
Y
---
L
L
L
-----
K
----
N
S
W
-
G
P
---------------------------------------------------
27
HHSearch
46.96
13%
-62
- C6 -
1PXV
2
SSPB_STAAU
A:
[15-154]
------------------------------------------------------------------------------
E
N
T
L
K
N
F
K
I
-
R
-
E
Q
----
Q
F
D
----
N
S
W
A
A
G
F
S
M
A
-------------
A
L
L
N
A
-
T
-----
K
N
TD
T
--
Y
N
-----
A
H
D
I
M
R
T
L
Y
P
E
V
S
E
-----
Q
D
L
P
N
C
-----------------------
A
T
F
P
N
Q
M
I
E
Y
G
K
S
Q
-
G
--
R
D
I
H
Y
Q
--
E
--
G
V
P
S
-
Y
----
N
Q
V
D
Q
L
T
K
-
D
N
--
V
-
G
I
M
I
L
A
--------------------
Q
S
V
S
---------
Q
-------
N
-
P
N
D
P
H
---
L
G
H
A
L
A
V
V
G
N
A
K
I
ND
Q
E
---------
K
---
L
I
Y
-----
W
----
N
P
W
-
D
T
---------------------------------------------------
52
Fugue
46.88
14%
-55
- C2 -
1EF1
1
MOES_HUMAN
A:
[1-294]
T
I
S
V
R
V
T
T
MD
A
E
L
E
F
A
I
Q
PNTT
G
K
Q
L
F
D
Q
V
V
K
T
I
G
L
R
E
V
W
F
F
G
L
Q
Y
Q
D
T
-
K
-----
G
F
S
T
W
L
K
L
N
K
K
V
T
A
QDV
R
K
E
S
P
L
L
F
K
F
R
A
K
F
-
Y
-
P
E
----
D
-
V
S
E
E
L
I
Q
--
D
I
T
Q
R
L
-------------
F
F
L
Q
V
-
K
E
G
I
L
N
D
D
--
I
--
Y
C
-----
P
P
E
T
A
V
L
L
A
S
Y
A
V
Q
S
K
Y
G
-
D
F
N
K
E
V
-----
H
K
S
G
Y
L
-
A
G
D
-
K
LLP
Q
R
V
L
E
Q
H
K
L
N
K
D
Q
W
E
E
R
-
I
--
Q
V
W
H
E
E
H
R
G
M
L
R
E
D
A
-
V
----
L
E
Y
L
K
I
A
Q
-
D
L
E
M
Y
G
V
N
Y
F
S
I
K
N
---
K
K
G
S
---
E
--
L
W
-
L
G
V
D
A
L
G
L
N
I
Y
E
QND
R
--
L
----
T
-
P
K
I
G
F
---
P
W
S
E
I
R
N
I
S
F
N
D
----
K
---------
K
---
F
V
I
-----
K
P
IDK
K
A
P
-
D
F
-----
V
-----
F
Y
A
P
R
L
R
I
N
K
R
I
L
A
L
C
M
G
N
------
H
E
L
-
Y
M
R
R
R
K
P----
30
HHSearch
46.45
18%
-51
- C6 -
3OIS
-
?
A:
[190-286]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
-
I
----
D
H
L
K
A
C
L
A
-
V
G
S
-
P
-
F
V
F
G
F
S
V
Y
---
N
S
W
V
---
G
--
N
N
S
L
P
V
R
I
P
---------
L
--
P
T---
K
-
N
D
T
L
E
---
G
G
H
A
V
L
C
V
G
Y
D
D
----
E
IR-------
H
---
F
R
I
-----
R
----
N
S
W
-
G
N
NVGED
G
-----
Y
F
W
M
P
Y
E
Y
I
S
N
T
Q
L
A
D
-
D
F
------
W
V
I
------------
22
HHSearch
45.06
9%
-67
- C6 -
1CV8
2
A:
[8-155]
--------------------------------------------------------------------------------
K
L
E
N
F
K
I
-
R
E
T
Q
----
G
-
N
----
N
G
W
C
A
G
Y
T
M
S
-------------
A
L
L
N
A
-
T
-----
Y
N
TN
K
--
Y
H
-----
A
E
A
V
M
R
F
L
H
P
N
L
Q
G
----------
Q
-----
Q
F
Q
--------
F
---
T
--
G
L
T
P
R
E
M
I
Y
F
G
Q
T
Q
-
G
--
R
S
P
Q
L
L
--
N
--
R
M
T
T
-
Y
----
N
E
V
D
N
L
T
K
-
N
N
K
-
G
-
I
A
I
L
G
S
R
V
------------------
E
S
R
---------------------
N
G
M
H
---
A
G
H
A
M
A
V
V
G
N
A
K
----
L
NNG
Q
E
----
V
---
I
I
I
-----
W
----
N
P
W
-
D
N
-----
G
-----
F
M
T
Q
D
A
K
N
N
-------------------------------
28
HHSearch
44.34
16%
-111
- C6 -
3BB7
-
?
A:
[276-338]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
----
D
I
V
F
S
E
L
T
-
K
G
H
-
P
-
L
I
Y
G
G
V
-----------------------------------------------
D
---
A
G
H
A
F
V
I
D
G
Y
N
K
A---
G
---------
L
---
V
S
V
-----
N
----
W
G
W
-
N
G
-----
D
V----
D
G
Y
Y
K
I
D
L
L
N
------------------------------
41
HHSearch
43.08
14%
-94
- C6 -
3U8E
1
?
A:
[116-186]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
----
S
A
L
L
D
A
V
A
-
K
-
Q
-
P
-
V
S
V
N
I
Y
T
S
S
T
S
F
Q
L
Y
---
T
--
G
P
-
G
I
F
A
G
S
---------
S
--
C
----
S
-
D
D
P
A
T
---
V
D
H
T
V
L
I
V
G
Y
G
S
----
N
GTN
A
D
----
Y
---
W
I
V
-----
K
----
N
S
W
-
G
----------------------------------------------------
33
HHSearch
42.26
11%
-76
- C6 -
1DEU
-
CATZ_HUMAN
A:
[137-220]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
-
R
----
E
K
M
M
A
E
I
Y
-
A
N
G
-
P
-
I
S
C
G
I
M
A
T
E
R
-
L
A
N
Y
---
T
---
G
-
G
I
Y
A
E
------------------
Y
-
Q
D
T
T
Y
---
I
N
H
V
V
S
V
A
G
W
G
I
S
DG
T
E
---------
Y
---
W
I
V
-----
R
----
N
S
W
-
G
E
-----
P
WGERG
W
L
R
I
V
T
S
T
Y
K
------------------------------
53
Fugue
41.83
14%
-43
- C3 -
3GN6
6
?
A:
[22-321]
--------------------------
F
N
P
W
T
D
A
A
L
D
T
I
V
N
-
Q
A
L
T
L
Y
A
E
M
R
V
V
P
A
H
H
D
A
F
L
A
A
I
D
T
V
S
A
K
---
L
R
V
L
P
G
F
L
S
L
A
L
K
Q
M
S
-
G
D
STMV
K
-
N
Y
P
E
T
Y
K
G
V
L
A
T
A
Y
L
D
G
V
A
A
GTQ
P
Y
F
Y
N
L
F
V
R
F
A
D
-----
G
R
--
A
--
A
R
-----
A
A
G
F
E
A
L
F
E
T
H
I
H
P
L
L
H
A
M
A
D
G
P
E
L
L
A
Y
R
A
V
L
Q
S
V
V
-
A
G
D
-
R
---
H
A
I
Y
R
G
A
E
E
I
R
S
F
L
R
R
P
-
V
EL
P
E
R
E
T
V
--
T
-
V
E
N
H
V
M
V
P---
E
D
K
H
A
A
W
E
-
P
Q
V
-
A
-
I
L
L
Q
V
A
Q
D
---
T
F
E
P
---
Q
--
D
E
-
P
S
G
V
G
L
---------
P
--
G
----
A
-
R
D
N
R
Y
Y
R
K
A
L
S
T
E
I
L
R
N
A
H
A
----
D
---------
G
G
L
R
A
Y
I
M
H
G
V
W
E
----
S
V
W
-
D
H
-----
E
-----
N
S
H
L
D
P
R
F
L
A
A
A
G
P
V
G
-
A
A
AVVGP
V
E
P
F
-
Y
-
L
T
R
R
L
V
V
A
D
42
HHSearch
41.82
10%
-70
- C6 -
2O6X
-
CATLL_FASHE
A:
[216-283]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
-
E
----
V
E
L
K
N
L
V
G
-
A
E
G
-
P
-
A
A
V
A
V
D
V
E
---
S
-
D
--------
F
-
M
M
Y
R
S
G
---------
I
Y
Q
S
----
Q
T
C
S
P
L
R
---
V
N
H
A
V
L
A
V
G
Y
G
T
Q
GG
T
D
---------
Y
---
W
I
V
-----
K
----
N
S
W
-
G
----------------------------------------------------
32
HHSearch
41.36
13%
-75
- C6 -
3I06
1
CYSP_TRYCR
A:
[121-185]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
-
E
----
A
Q
I
A
A
W
L
A
-
V
N
G
-
P
-
V
A
V
A
V
D
A
S
---
S
W
M
T
---
Y
--
T
G
-
G
V
M
T
-------------------
S
-
C
V
S
E
Q
---
L
D
H
G
V
L
L
V
G
Y
N
D
SAA
V
P
---------
Y
---
W
I
I
-----
K
----
N
S
W
-
T
----------------------------------------------------
39
HHSearch
41.27
14%
-69
- C6 -
2WBF
4
X:
[157-228]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
----
K
I
I
K
T
E
V
M
-
N
K
G
-
S
-
V
I
A
Y
I
K
A
E
-----
N
V
---------
M
G
Y
E
F
S
---------
G
--
K
KVKN
L
-
C
G
D
D
T
---
A
D
H
A
V
N
I
V
G
Y
G
N
----
Y
VNSEGEKKS
Y
---
W
I
V
-----
R
----
N
S
W
-
G
----------------------------------------------------
37
HHSearch
40.19
15%
-82
- C6 -
3CBJ
-
?
A:
[162-228]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
-
E
----
K
D
I
M
A
E
I
Y
-
K
N
G
-
P
-
V
E
G
A
F
S
V
Y
---
S
D
F
L
---
L
Y-
K
S
-
G
V
Y
Q
H
V
-------------------
T
G
E
M
M
---
G
G
H
A
I
R
I
L
G
W
G
V
E
NG
T
P
---------
Y
---
W
L
V
-----
A
----
N
S
W
-
N
----------------------------------------------------