@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0744: (2016-03-18 )
MLEVKHLKKSYKLGKKNETPVLKDINVTIQDGEFAAIIGKSGSGKSTLLNIISGLDTDYEGKVLYNGEDLQDIDLDAYHFNHIGFIFQSFHLVNHMSVVENVKVPLYLNPELSESDRNARALDLLKQVGLEDFASKKPTQLSGGQKQRVAIARSLANNPDMIIADEPTGALDSVTSDEIIKLLKALAAKGTTVIVVTHDLNIADQTDAVLRLADGEVISFERKKEVVQKVTHKNEKKLRLNWWATAKISFKSFFNRKFRNLLVALGTSIGIIAILLAFGLGNGVNQSLSKIFGTTFSPNQITTYYKEDGGSKSPEPTTPLTSSEIKKIKQLYEDENITEIYERTTVQGIKFEYDGEYLKGISGEMQEANFKPSRYEDLTVKDEYLLSGKMVTSDETGAVIPSSVAKAILGKKDSDELTKSDGDKLIGKKITLVYAGRNSDTKNTVKTETTISGITNPSKEGFARGFDVSTKTMNDFIKTTGIEKPILSVDAFTKTTAEAEEIVEKYEDNKDWANYSITNANAFVDTFSQFTDIIVYLIAFIAGLSLAVAGVMIAIVLYIGVVERTREIGVFRAIGYRKRHIRGLFMMEASYIIILANVLSSLVAVTIAKIASPILETKIGFEDMIHISFWNFLVTLAITITIGFIFSIYPSNKAAKLDAAEALRSE
Atome Classification :
(47 SA)
---.........10........20...-.....30........40........50........60......---..70----.--...-...---.--.--80.-...-------...--.90........100-..--....--.--110-..-----..--....120.......--.130-.....-..140.......150.......160.......170.----......180.....-.-.-190.......200.-..-.-..-.210.......220.......230.......240.......250.......260...-------------....270.......280......-.290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---ML
E
V
K
H
L
K
K
S
YKLGKKNET
P
V
L
K
D
-
I
N
V
T
I
QDG
E
F
A
A
I
IGKSGS
G
K
S
T
L
L
N
I
I
S
GLDTDYE
G
K
V
L
YNG---EDL-----Q--DID-LD
A
---
Y
--
H
--
F
N
H
-
I
G
F
-------
I
F
Q
--
S
F
H
L
V
N
H
M
S
V
V
ENV-K
V
--
P
L
Y
L--N--PE--LS-----ES--DR
N
A
R
-
A
L
D
L
L
K
QV--G
L
E
D
-
F
ASKK-PTQLSGG
Q
K
Q
R
V
A
I
A
R
S
LANNP
D
M
I
I
ADEPTGALDS----V
T
S
D
E
I
I
K
L
L
K
A
L
A-A-K-G
T
T
V
I
V
V
THDLNIA-DQ-T-
D
A
-
V
L
R
LADG
E
V
I
S
F
E
R
K
K
E
V
V
Q
K
V
THKNE
K
K
L
R
L
N
W
W
A
T
A
K
I
S
F
K
S
F
F
N
R
K
F
R
N
L
L
V
A
L-------------GT
S
I
G
I
I
A
I
L
L
A
F
GLGN
G
V
N
Q
S
L
-
S
K
I
FGTTFSPN
Q
I
T
T
Y
Y
KEDGGSKSPEPTTPL
T
S
S
E
I
K
K
I
K
Q
L
YEDE
N
I
T
E
I
Y
E
RTTVQ
G
I
K
F
E
YDG
E
Y
L
K
GISGE
M
Q
EANFKPSRYED
L
T
VK
D
E
Y
L
LSG
K
M
VTSDETGAV
I
P
S
S
V
A
K
A
I
LGKKD
S
D
E
LTKSDGDKLI
G
K
K
I
T
L
V
Y
AGRNSDTKN
T
V
KT
E
T
T
ISGITNP
S
K
E
GFARGFDV
S
T
K
T
M
N
D
F
I
K
TTGIEKPILSV
D
A
FTKTTA
E
A
E
E
I
V
E
K
YEDNKDWA
N
Y
S
ITN
A
N
A
F
V
D
T
F
S
Q
F
T
D
I
I
V
Y
L
I
A
F
I
A
G
L
S
L
A
V
A
G
V
M
I
A
I
V
L
Y
I
G
V
V
E
R
T
R
EI
G
V
F
R
AIG
Y
R
K
R
H
I
R
G
L
F
M
MEAS
Y
I
I
I
L
A
N
V
L
S
S
L
V
A
V
T
I
A
K
I
A
S
P
I
L
E
TKIG
F
E
D
M
I
H
I
S
F
W
N
F
L
V
T
L
A
I
T
I
T
I
G
F
I
F
S
IYPSNKAAK
L
D
A
A
E
A
LRSE
21
PsiBlast_CBE
76.14
48%
-86
- C2 -
1L2T
4
Y796_METJA
B:
[1-223]
---
M
I
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
-
I
Y
A
L
K
N
-
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
IKT
N
D
L
-----
D
--
D
D
E
-
L
T
K
---
I
--
R
--
R
D
K
-
I
G
F
-------
V
F
Q
--
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
-
E
L
--
P
L
I
F
KY
R
--
G
A
--
M
S
-----
G
E
--
E
R
R
K
R
-
A
L
E
C
L
K
M
A
--
E
L
E
E
R
F
A
N
H
K
-
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
----
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
-
E
-
E
D
G
K
T
V
V
V
V
T
H
D
I
N
V
A
-
R
F
-
G
-
E
R
-
I
I
Y
L
K
D
G
E
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
75.52
48%
-74
- C2 -
1F3O
2
Y796_METJA
A:
[2-228]
----
I
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
-
I
Y
A
L
K
N
-
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
IKT
N
D
L
-----
D
--
D
D
E
-
L
T
K
---
I
--
R
--
R
D
K
-
I
G
F
-------
V
F
Q
--
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
-
E
L
--
P
L
I
F
--
K
--
Y
R
--
G
A
-----
M
S
G
E
E
R
R
K
R
-
A
L
E
C
L
K
M
A
--
E
L
E
E
R
F
A
N
H
K
-
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
E
P
T
G
A
L
D
S
----
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
-
E
-
E
D
G
K
T
V
V
V
V
T
H
D
I
N
V
A
-
R
F
-
G
-
E
R
-
I
I
Y
L
K
D
G
E
V
E
R
E
E
K
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
104
Fugue
75.48
26%
-63
- C2 -
1Z47
1
?
A:
[11-355]
GSM
T
I
E
F
V
G
V
E
K
I
Y
P
----
G
G
A
R
S
V
R
G
-
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
G
---
K
R
V
-----
T
--
D
L
P
-
P
Q
K
----------
R
N
-
V
G
L
-------
V
F
Q
--
N
Y
A
L
F
Q
H
M
T
V
Y
D
N
V
-
S
F
--
G
L
R
E
-----
K
R
--
V
P
-----
K
D
--
E
M
D
A
R
-
V
R
E
L
L
R
F
M
--
R
L
E
S
-
Y
A
N
R
F
-
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
----
Q
I
R
R
E
L
R
T
F
V
R
Q
V
H
-
D
-
E
M
G
V
T
S
V
F
V
T
H
D
Q
E
E
A
-
L
E
V
A
-
D
R
-
V
L
V
L
H
E
G
N
V
E
Q
F
G
T
P
E
E
V
Y
E
K
P
G
---------
T
L
F
V
A
S
F
I
G
E
S
N
V
W
T
R
A
V
Q
N
G
R
I
E
V
AG
A
A
L
P
V
DPAVSE
G
S
E
V
A
V
V
V
R
P
K
D
V
E
L
Q
P
A
S
E
R
E
A
H
A
Q
V
V
R
S
A
F
K
G
S
Y
S
A
C
W
I
R
T
K
D
G
E
V
W
E
V
H
V
P
S
A
D
R
H
R
W
S
P
G
A
W
V
H
M
N
V
T
R
W
F
I
F
P
R
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
75.29
48%
-85
- C2 -
3TIF
7
Y796_METJA
B:
[1-223]
---
M
V
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
-
I
Y
A
L
K
N
-
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
IKT
N
D
L
-----
D
--
D
D
E
-
L
T
K
---
I
--
R
--
R
D
K
-
I
G
F
-------
V
F
Q
--
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
-
E
L
--
P
L
I
F
--
K
--
Y
R
GA
M
S
-----
G
E
--
E
R
R
K
R
-
A
L
E
C
L
K
M
A
--
E
L
E
E
R
F
A
N
H
K
-
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
----
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
-
E
-
E
D
G
K
T
V
V
V
V
T
H
D
I
N
V
A
-
R
F
-
G
-
E
R
-
I
I
Y
L
K
D
G
E
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
74.77
48%
-81
- C2 -
1L2T
4
Y796_METJA
A:
[1-223]
---
M
I
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
-
I
Y
A
L
K
N
-
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
IKT
N
D
L
-----
D
--
D
D
E
-
L
T
K
---
I
--
R
--
R
D
K
-
I
G
F
-------
V
F
Q
--
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
-
E
L
--
P
L
I
F
KY
R
--
G
A
--
M
S
-----
G
E
--
E
R
R
K
R
-
A
L
E
C
L
K
M
A
--
E
L
E
E
R
F
A
N
H
K
-
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
G
A
L
D
S
----
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
-
E
-
E
D
G
K
T
V
V
V
V
T
H
D
I
N
V
A
-
R
F
-
G
-
E
R
-
I
I
Y
L
K
D
G
E
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
74.05
48%
-78
- C2 -
3TIF
7
Y796_METJA
A:
[1-223]
---
M
V
K
L
K
N
V
T
K
T
Y
K
M
G
E
E
I
-
I
Y
A
L
K
N
-
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
IKT
N
D
L
-----
D
--
D
D
E
-
L
T
K
---
I
--
R
--
R
D
K
-
I
G
F
-------
V
F
Q
--
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
-
E
L
--
P
L
I
F
--
K
--
Y
R
G
A
M
S
-----
G
E
--
E
R
R
K
R
-
A
L
E
C
L
K
M
A
--
E
L
E
E
R
F
A
N
H
K
-
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
----
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
-
E
-
E
D
G
K
T
V
V
V
V
T
H
D
I
N
V
A
-
R
F
-
G
-
E
R
-
I
I
Y
L
K
D
G
E
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
130
HHSearch
73.52
48%
-75
- C2 -
3TIF
7
Y796_METJA
A:
[1-230]
---
M
V
K
L
K
N
V
T
K
T
Y
K
M
G
-
E
E
I
I
Y
A
L
K
N
-
V
N
L
N
I
K
E
G
E
F
V
S
I
M
G
P
S
G
S
G
K
S
T
M
L
N
I
I
G
C
L
D
K
P
T
E
G
E
V
Y
I
D
N
---
I
K
T
-----
N
--
D
L
D
-
D
D
E
L
T
K
I
--
R
--
R
D
K
-
I
G
F
-------
V
F
Q
--
Q
F
N
L
I
P
L
L
T
A
L
E
N
V
-
E
L
--
P
L
I
F
--
K
--
Y
R
G
A
M
S
-----
G
E
--
E
R
R
K
R
-
A
L
E
C
L
K
M
A
--
E
L
E
E
R
F
A
N
H
K
-
P
N
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
N
N
P
P
I
I
L
A
D
Q
P
T
W
A
L
D
S
----
K
T
G
E
K
I
M
Q
L
L
K
K
L
N
-
E
E
D
-
G
K
T
V
V
V
V
T
H
D
I
N
V
A
-
R
F
-
G
-
E
R
-
I
I
Y
L
K
D
G
E
V
E
R
E
E
K
L
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
72.44
38%
-78
- C2 -
3C4J
4
?
B:
[24-256]
---
M
I
D
V
H
Q
L
K
K
S
F
-----
G
S
L
E
V
L
K
G
-
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
---
I
N
L
-----
K
AK
D
T
N
-
L
N
K
---
V
--
R
---
E
E
-
V
G
M
-------
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
--
A
P
M
K
--
V
--
R
K
--
W
P
-----
R
E
--
K
A
E
A
K
-
A
M
E
L
L
D
K
V
--
G
L
K
D
-
K
A
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
----
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
-
R
E
-
V
G
D
R
-
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
72.31
38%
-78
- C2 -
2OLJ
4
?
A:
[24-256]
---
M
I
D
V
H
Q
L
K
K
S
F
-----
G
S
L
E
V
L
K
G
-
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
---
I
N
L
-----
K
AK
D
T
N
-
L
N
K
---
V
--
R
---
E
E
-
V
G
M
-------
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
--
A
P
M
K
--
V
--
R
K
--
W
P
-----
R
E
--
K
A
E
A
K
-
A
M
E
L
L
D
K
V
--
G
L
K
D
-
K
A
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
----
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
-
R
E
-
V
G
D
R
-
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
103
Fugue
72.15
25%
-57
- C2 -
3TUZ
3
METN_ECOLI
H:
[23-362]
--H
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
-
R
T
I
Q
A
L
N
N
-
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
---
Q
E
L
-----
T
--
T
L
S
-
E
S
E
---
L
--
T
KA
R
R
Q
-
I
G
M
-------
I
F
Q
--
H
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
--
P
L
E
L
--
D
---
N
--
T
P
-----
K
D
--
E
V
K
R
R
-
V
T
E
L
L
S
L
V
--
G
L
G
D
-
K
H
D
S
Y
-
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
----
A
T
T
R
S
I
L
E
L
L
K
D
I
N
-
R
-
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
-
K
R
I
C
-
D
C
-
V
A
V
I
S
N
G
E
L
I
E
----
Q
D
T
V
S
E
V
F
S
H
P
K
T
P
L
A
Q
K
F
I
Q
S
T
L
H
L
D
I
P
E
D
Y
Q
E
R
L
Q
A
E
P
F
T
-------------
D
C
V
P
M
L
R
L
E
F
T
G
Q
S
V
D
A
P
L
L
S
E
T
-
A
R
R
F
N
V
N
N
N
I
I
S
A
Q
M
D
Y
A
G
G
V
K
F
G
I
M
L
T
E
M
H
G
T
Q
Q
D
T
Q
A
A
I
A
W
L
Q
E
H
H
V
K
V
E
V
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
71.76
38%
-74
- C2 -
3C4J
3
?
A:
[24-256]
---
M
I
D
V
H
Q
L
K
K
S
F
-----
G
S
L
E
V
L
K
G
-
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
---
I
N
L
-----
K
AK
D
T
N
-
L
N
K
---
V
--
R
---
E
E
-
V
G
M
-------
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
--
A
P
M
K
--
V
--
R
K
--
W
P
-----
R
E
--
K
A
E
A
K
-
A
M
E
L
L
D
K
V
--
G
L
K
D
-
K
A
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
----
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
-
R
E
-
V
G
D
R
-
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
PsiBlast_CBE
71.41
38%
-70
- C2 -
2OLK
2
?
B:
[24-256]
---
M
I
D
V
H
Q
L
K
K
S
F
-----
G
S
L
E
V
L
K
G
-
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
---
I
N
L
-----
K
AK
D
T
N
-
L
N
K
---
V
--
R
---
E
E
-
V
G
M
-------
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
--
A
P
M
K
--
V
--
R
K
--
W
P
-----
R
E
--
K
A
E
A
K
-
A
M
E
L
L
D
K
V
--
G
L
K
D
-
K
A
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
----
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
-
R
E
-
V
G
D
R
-
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
PsiBlast_CBE
71.25
38%
-73
- C2 -
2OLK
1
?
D:
[24-256]
---
M
I
D
V
H
Q
L
K
K
S
F
-----
G
S
L
E
V
L
K
G
-
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
---
I
N
L
-----
K
AK
D
T
N
-
L
N
K
---
V
--
R
---
E
E
-
V
G
M
-------
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
--
A
P
M
K
--
V
--
R
K
--
W
P
-----
R
E
--
K
A
E
A
K
-
A
M
E
L
L
D
K
V
--
G
L
K
D
-
K
A
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
----
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
-
R
E
-
V
G
D
R
-
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
71.19
38%
-76
- C2 -
2OUK
1
?
A:
[24-256]
---
M
I
D
V
H
Q
L
K
K
S
F
-----
G
S
L
E
V
L
K
G
-
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
---
I
N
L
-----
K
AK
D
T
N
-
L
N
K
---
V
--
R
---
E
E
-
V
G
M
-------
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
--
A
P
M
K
--
V
--
R
K
--
W
P
-----
R
E
--
K
A
E
A
K
-
A
M
E
L
L
D
K
V
--
G
L
K
D
-
K
A
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
----
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
-
R
E
-
V
G
D
R
-
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
PsiBlast_CBE
70.77
35%
-85
- C2 -
3TUZ
1
METN_ECOLI
C:
[24-251]
---
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
-
I
Q
A
L
N
N
-
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
---
Q
E
L
-----
T
--
T
L
S
-
E
S
E
---
L
TK
A
--
R
R
Q
-
I
G
M
-------
I
F
Q
--
H
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
--
P
L
E
L
D-
N
--
T
P
--
K
D
-----
E
V
--
K
R
--
R
-
V
T
E
L
L
S
L
V
--
G
L
G
D
-
K
H
D
S
Y
-
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
----
A
T
T
R
S
I
L
E
L
L
K
D
I
N
-
R
-
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
-
K
R
I
C
-
D
C
-
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
70.59
38%
-71
- C2 -
2Q0H
4
?
B:
[24-256]
---
M
I
D
V
H
Q
L
K
K
S
F
-----
G
S
L
E
V
L
K
G
-
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
---
I
N
L
-----
K
AK
D
T
N
-
L
N
K
---
V
--
R
---
E
E
-
V
G
M
-------
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
--
A
P
M
K
--
V
--
R
K
--
W
P
-----
R
E
--
K
A
E
A
K
-
A
M
E
L
L
D
K
V
--
G
L
K
D
-
K
A
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
----
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
-
R
E
-
V
G
D
R
-
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
48
PsiBlast_CBE
70.40
33%
-71
- C2 -
1Z47
1
?
A:
[15-236]
----
I
E
F
V
G
V
E
K
I
Y
P
G
G
A
R
S
----
V
R
G
-
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
G
---
K
R
V
-----
T
--
D
L
P
-
P
Q
K
----------
R
N
-
V
G
L
-------
V
F
Q
--
N
Y
A
L
F
Q
H
M
T
V
Y
D
N
V
-
S
F
--
G
L
R
---
E
--
K
R
--
V
P
-----
K
D
--
E
M
D
A
R
-
V
R
E
L
L
R
F
M
--
R
L
E
S
-
Y
A
N
R
F
-
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
----
Q
I
R
R
E
L
R
T
F
V
R
Q
V
H
-
D
-
E
M
G
V
T
S
V
F
V
T
H
D
Q
E
E
A
L
E
V
-
A
-
D
R
-
V
L
V
L
H
E
G
N
V
E
Q
F
G
T
P
E
E
V
Y
E
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
PsiBlast_PDB
70.29
38%
-69
- C2 -
2OLK
1
?
A:
[24-256]
---
M
I
D
V
H
Q
L
K
K
S
F
-----
G
S
L
E
V
L
K
G
-
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
---
I
N
L
-----
K
AK
D
T
N
-
L
N
K
---
V
--
R
---
E
E
-
V
G
M
-------
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
--
A
P
M
K
--
V
--
R
K
--
W
P
-----
R
E
--
K
A
E
A
K
-
A
M
E
L
L
D
K
V
--
G
L
K
D
-
K
A
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
----
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
-
R
E
-
V
G
D
R
-
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
47
PsiBlast_CBE
70.21
33%
-71
- C2 -
1Z47
1
?
B:
[15-236]
----
I
E
F
V
G
V
E
K
I
Y
P
G
G
A
R
S
----
V
R
G
-
V
S
F
Q
I
R
E
G
E
M
V
G
L
L
G
P
S
G
S
G
K
T
T
I
L
R
L
I
A
G
L
E
R
P
T
K
G
D
V
W
I
G
G
---
K
R
V
-----
T
--
D
L
P
-
P
Q
K
----------
R
N
-
V
G
L
-------
V
F
Q
--
N
Y
A
L
F
Q
H
M
T
V
Y
D
N
V
-
S
F
--
G
L
R
---
E
--
K
R
--
V
P
-----
K
D
--
E
M
D
A
R
-
V
R
E
L
L
R
F
M
--
R
L
E
S
-
Y
A
N
R
F
-
P
H
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
A
P
R
P
Q
V
L
L
F
D
E
P
F
A
A
I
D
T
----
Q
I
R
R
E
L
R
T
F
V
R
Q
V
H
-
D
-
E
M
G
V
T
S
V
F
V
T
H
D
Q
E
E
A
L
E
V
-
A
-
D
R
-
V
L
V
L
H
E
G
N
V
E
Q
F
G
T
P
E
E
V
Y
E
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
PsiBlast_PDB
70.13
35%
-83
- C2 -
3TUI
1
METN_ECOLI
C:
[24-251]
---
M
I
K
L
S
N
I
T
K
V
F
H
Q
G
T
R
T
-
I
Q
A
L
N
N
-
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
G
---
Q
E
L
-----
T
--
T
L
S
-
E
S
E
---
L
TK
A
--
R
R
Q
-
I
G
M
-------
I
F
Q
--
H
F
N
L
L
S
S
R
T
V
F
G
N
V
-
A
L
--
P
L
E
L
D-
N
--
T
P
--
K
D
-----
E
V
--
K
R
--
R
-
V
T
E
L
L
S
L
V
--
G
L
G
D
-
K
H
D
S
Y
-
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
----
A
T
T
R
S
I
L
E
L
L
K
D
I
N
-
R
-
R
L
G
L
T
I
L
L
I
T
H
E
M
D
V
V
-
K
R
I
C
-
D
C
-
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
PsiBlast_CBE
69.80
38%
-67
- C2 -
2OLJ
3
?
B:
[24-256]
---
M
I
D
V
H
Q
L
K
K
S
F
-----
G
S
L
E
V
L
K
G
-
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
---
I
N
L
-----
K
AK
D
T
N
-
L
N
K
---
V
--
R
---
E
E
-
V
G
M
-------
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
--
A
P
M
K
--
V
--
R
K
--
W
P
-----
R
E
--
K
A
E
A
K
-
A
M
E
L
L
D
K
V
--
G
L
K
D
-
K
A
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
----
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
-
R
E
-
V
G
D
R
-
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
69.79
38%
-69
- C2 -
2Q0H
4
?
A:
[24-256]
---
M
I
D
V
H
Q
L
K
K
S
F
-----
G
S
L
E
V
L
K
G
-
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
---
I
N
L
-----
K
AK
D
T
N
-
L
N
K
---
V
--
R
---
E
E
-
V
G
M
-------
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
--
A
P
M
K
--
V
--
R
K
--
W
P
-----
R
E
--
K
A
E
A
K
-
A
M
E
L
L
D
K
V
--
G
L
K
D
-
K
A
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
----
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
-
R
E
-
V
G
D
R
-
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
69.63
38%
-70
- C2 -
3C41
3
?
J:
[3-235]
---
M
I
D
V
H
Q
L
K
K
S
F
-----
G
S
L
E
V
L
K
G
-
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
---
I
N
L
-----
K
AK
D
T
N
-
L
N
K
---
V
--
R
---
E
E
-
V
G
M
-------
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
--
A
P
M
K
--
V
--
R
K
--
W
P
-----
R
E
--
K
A
E
A
K
-
A
M
E
L
L
D
K
V
--
G
L
K
D
-
K
A
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
----
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
-
R
E
-
V
G
D
R
-
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
69.61
38%
-71
- C2 -
3C41
3
?
K:
[3-235]
---
M
I
D
V
H
Q
L
K
K
S
F
-----
G
S
L
E
V
L
K
G
-
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
---
I
N
L
-----
K
AK
D
T
N
-
L
N
K
---
V
--
R
---
E
E
-
V
G
M
-------
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
--
A
P
M
K
--
V
--
R
K
--
W
P
-----
R
E
--
K
A
E
A
K
-
A
M
E
L
L
D
K
V
--
G
L
K
D
-
K
A
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
----
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
-
R
E
-
V
G
D
R
-
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
PsiBlast_CBE
69.60
38%
-67
- C2 -
2OLK
1
?
C:
[24-256]
---
M
I
D
V
H
Q
L
K
K
S
F
-----
G
S
L
E
V
L
K
G
-
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
G
---
I
N
L
-----
K
AK
D
T
N
-
L
N
K
---
V
--
R
---
E
E
-
V
G
M
-------
V
F
Q
--
R
F
N
L
F
P
H
M
T
V
L
N
N
I
-
T
L
--
A
P
M
K
--
V
--
R
K
--
W
P
-----
R
E
--
K
A
E
A
K
-
A
M
E
L
L
D
K
V
--
G
L
K
D
-
K
A
H
A
Y
-
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
----
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
-
R
E
-
V
G
D
R
-
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
F
D
R
P
Q
H
E
R
T
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
67.99
36%
-76
- C2 -
4YMV
1
?
J:
[16-231]
-----------------------
V
L
K
G
-
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
---
V
K
I
-----
N
--
N
G
K
-
V
N
I
---
N
--
K
--
V
R
Q
K
V
G
M
-------
V
F
Q
--
H
F
N
L
F
P
H
L
T
A
I
E
N
I
-
T
L
--
A
P
V
K
--
V
--
K
K
--
M
N
-----
K
K
--
E
A
E
E
L
-
A
V
D
L
L
A
K
V
--
G
L
L
D
-
K
K
D
Q
Y
-
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
----
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
-
R
E
-
V
G
D
R
-
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
--
K
N
E
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
PsiBlast_CBE
67.88
36%
-75
- C2 -
4YMV
1
?
A:
[16-231]
-----------------------
V
L
K
G
-
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
---
V
K
I
-----
N
--
N
G
K
-
V
N
I
---
N
--
K
--
V
R
Q
K
V
G
M
-------
V
F
Q
--
H
F
N
L
F
P
H
L
T
A
I
E
N
I
-
T
L
--
A
P
V
K
--
V
--
K
K
--
M
N
-----
K
K
--
E
A
E
E
L
-
A
V
D
L
L
A
K
V
--
G
L
L
D
-
K
K
D
Q
Y
-
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
----
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
-
R
E
-
V
G
D
R
-
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
--
K
N
E
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
PsiBlast_CBE
67.79
36%
-79
- C2 -
4YMU
2
?
A:
[16-231]
-----------------------
V
L
K
G
-
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
---
V
K
I
-----
N
--
N
G
K
-
V
N
I
---
N
--
K
--
V
R
Q
K
V
G
M
-------
V
F
Q
--
H
F
N
L
F
P
H
L
T
A
I
E
N
I
-
T
L
--
A
P
V
K
--
V
--
K
K
--
M
N
-----
K
K
--
E
A
E
E
L
-
A
V
D
L
L
A
K
V
--
G
L
L
D
-
K
K
D
Q
Y
-
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
----
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
-
R
E
-
V
G
D
R
-
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
--
K
N
E
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
67.25
39%
-67
- C2 -
4U00
3
?
A:
[19-235]
-----------------------
V
L
K
G
-
I
H
L
E
V
A
P
G
E
K
L
V
I
I
G
P
S
G
S
G
K
S
T
L
I
R
T
I
N
R
L
E
D
F
Q
E
G
E
V
V
V
D
G
---
L
S
V
-----
K
--
D
D
R
-
A
L
R
---
E
--
I
--
R
R
E
-
V
G
M
-------
V
F
Q
--
Q
F
N
L
F
P
H
M
T
V
L
E
N
V
-
T
L
--
A
P
M
R
--
V
--
R
R
--
W
P
-----
R
E
--
K
A
E
K
K
-
A
L
E
L
L
E
R
V
--
G
I
L
D
-
Q
A
R
K
Y
-
P
A
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
----
E
M
V
G
E
V
L
D
V
M
R
D
L
A
-
Q
-
G
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
-
R
E
-
V
A
D
R
-
V
V
F
M
D
G
G
Q
I
V
E
E
G
R
P
E
E
I
---
F
T
R
P
K
E
E
R
T
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
67.20
36%
-75
- C2 -
4YMU
2
?
J:
[16-231]
-----------------------
V
L
K
G
-
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
G
---
V
K
I
-----
N
--
N
G
K
-
V
N
I
---
N
--
K
--
V
R
Q
K
V
G
M
-------
V
F
Q
--
H
F
N
L
F
P
H
L
T
A
I
E
N
I
-
T
L
--
A
P
V
K
--
V
--
K
K
--
M
N
-----
K
K
--
E
A
E
E
L
-
A
V
D
L
L
A
K
V
--
G
L
L
D
-
K
K
D
Q
Y
-
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
----
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
-
N
-
E
-
G
M
T
M
V
V
V
T
H
E
M
G
F
A
-
R
E
-
V
G
D
R
-
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
F
Y
R
A
--
K
N
E
R
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
118
HHSearch
63.61
31%
-63
- C2 -
3FVQ
3
FBPC_NEIG1
A:
[4-234]
---
A
L
H
I
G
H
L
S
K
S
F
Q
-----
N
T
P
V
L
N
D
-
I
S
L
S
L
D
P
G
E
I
L
F
I
I
G
A
S
G
C
G
K
T
T
L
L
R
C
L
A
G
F
E
Q
P
D
S
G
E
I
S
L
S
G
---
K
T
I
-----
F
--
S
K
N
T
N
L
P
---
V
--
R
--
E
R
R
-
L
G
Y
-------
L
V
Q
--
E
G
V
L
F
P
H
L
T
V
Y
R
N
I
-
A
Y
--
G
L
G
N
--
G
--
K
G
--
R
------
T
A
--
Q
E
R
Q
R
-
I
E
A
M
L
E
L
T
--
G
I
S
E
-
L
A
G
R
Y
-
P
H
E
L
S
G
G
Q
Q
Q
R
A
A
L
A
R
A
L
A
P
D
P
E
L
I
L
L
D
E
P
F
S
A
L
D
E
----
Q
L
R
R
Q
I
R
E
D
M
I
A
A
L
R
A
-
N
-
G
K
S
A
V
F
V
S
H
D
R
E
E
A
L
Q
Y
-
A
-
D
R
-
I
A
V
M
K
Q
G
R
I
L
Q
T
A
S
P
H
E
L
Y
R
Q
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
71
PsiBlast_CBE
62.44
32%
-68
- C2 -
4HLU
3
ECFA1_THEMA
C:
[26-246]
-----------------------
V
L
K
D
-
V
N
A
E
F
E
T
G
K
I
Y
V
V
V
G
K
N
G
S
G
K
T
T
L
L
K
I
L
A
G
L
-
L
A
A
A
G
E
I
F
L
D
G
---
S
P
A
-----
D
--
P
F
L
-
L
R
-----------
K
N
-
V
G
Y
-------
V
F
Q
NP
S
S
Q
I
I
G
-
A
T
V
E
E
D
V
-
A
F
--
S
L
E
I
--
M
--
G
---
L
D
-----
E
S
--
E
M
R
K
R
-
I
K
K
V
L
E
L
V
--
G
L
S
G
-
L
A
A
A
D
-
P
L
N
L
S
G
G
Q
K
Q
R
L
A
I
A
S
M
L
A
R
D
T
R
F
L
A
L
D
E
P
V
S
M
L
D
P
----
P
S
Q
R
E
I
F
Q
V
L
E
S
L
K
-
N
-
E
-
G
K
G
I
I
L
V
T
H
E
L
E
Y
L
-
D
D
-
M
-
D
F
-
I
L
H
I
S
N
G
T
I
D
F
C
G
S
W
E
E
F
V
E
R
E
F
D
D
V
E
I
P
F
K
W
K
L
W
K
K
C
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
70
PsiBlast_CBE
62.19
32%
-67
- C2 -
4HLU
2
ECFA1_THEMA
D:
[26-246]
-----------------------
V
L
K
D
-
V
N
A
E
F
E
T
G
K
I
Y
V
V
V
G
K
N
G
S
G
K
T
T
L
L
K
I
L
A
G
L
-
L
A
A
A
G
E
I
F
L
D
G
---
S
P
A
-----
D
--
P
F
L
-
L
R
-----------
K
N
-
V
G
Y
-------
V
F
Q
NP
S
S
Q
I
I
G
-
A
T
V
E
E
D
V
-
A
F
--
S
L
E
I
--
M
--
G
---
L
D
-----
E
S
--
E
M
R
K
R
-
I
K
K
V
L
E
L
V
--
G
L
S
G
-
L
A
A
A
D
-
P
L
N
L
S
G
G
Q
K
Q
R
L
A
I
A
S
M
L
A
R
D
T
R
F
L
A
L
D
E
P
V
S
M
L
D
P
----
P
S
Q
R
E
I
F
Q
V
L
E
S
L
K
-
N
-
E
-
G
K
G
I
I
L
V
T
H
E
L
E
Y
L
-
D
D
-
M
-
D
F
-
I
L
H
I
S
N
G
T
I
D
F
C
G
S
W
E
E
F
V
E
R
E
F
D
D
V
E
I
P
F
K
W
K
L
W
K
K
C
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
PsiBlast_CBE
60.92
38%
-81
- C2 -
1B0U
4
HISP_SALTY
A:
[21-231]
-----------------------
V
L
K
G
-
V
S
L
Q
A
R
A
G
D
V
I
S
I
I
G
S
S
G
S
G
K
S
T
F
L
R
C
I
N
F
L
E
K
P
S
E
G
A
I
I
V
N
G
---
Q
N
I
N
L
V
R
D
K
--
D
G
Q
-
L
K
V
---
A
--
D
--
K
N
Q
-
L
R
L
L
R
T
R
L
T
M
V
F
Q
--
H
F
N
L
W
S
H
M
T
V
L
E
N
V
M
E
A
--
P
I
Q
V
--
L
--
G
---
L
S
-----
K
H
--
D
A
R
E
R
-
A
L
K
Y
L
A
K
V
--
G
I
D
E
-
R
A
Q
G
K
Y
P
V
H
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
E
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
----
E
L
V
G
E
V
L
R
I
M
Q
Q
L
A
-
E
-
E
-
G
K
T
M
V
V
V
T
H
E
M
G
F
A
-
R
H
-
V
-
S
S
H
V
I
F
L
H
Q
G
K
I
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
52
PsiBlast_CBE
57.82
32%
-50
- C2 -
2HYD
3
Y1866_STAAM
B:
[340-565]
----
I
D
I
D
H
V
S
F
Q
Y
N
---
D
N
E
A
P
I
L
K
D
-
I
N
L
S
I
E
K
G
E
T
V
A
F
V
G
M
S
G
G
G
K
S
T
L
I
N
L
I
P
R
F
Y
D
V
T
S
G
Q
I
L
I
D
G
---
H
N
I
-----
K
--
D
F
--
L
T
G
---
S
--
L
--
R
N
Q
-
I
G
L
-------
V
Q
Q
--
D
-
N
I
L
F
S
D
T
V
K
E
N
I
-
L
L
GR
P
T
A
T
--
D
--
E
E
--
V
V
-----
E
A
--
A
K
M
A
N
-
A
H
D
F
I
M
N
L
PQ
G
Y
D
T
-
E
V
G
E
R
-
G
V
K
L
S
G
G
Q
K
Q
R
L
S
I
A
R
I
F
L
N
N
P
P
I
L
I
L
D
E
A
T
S
A
L
D
-----
L
E
S
E
S
I
I
Q
E
A
L
D
V
L
-
S
-
K
-
D
R
T
T
L
I
V
A
H
R
L
S
T
I
-
T
H
-
A
-
D
K
-
I
V
V
I
E
N
G
H
I
V
E
T
G
T
H
R
E
L
I
A
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
53
PsiBlast_CBE
57.64
32%
-50
- C2 -
2HYD
3
Y1866_STAAM
A:
[340-565]
----
I
D
I
D
H
V
S
F
Q
Y
N
---
D
N
E
A
P
I
L
K
D
-
I
N
L
S
I
E
K
G
E
T
V
A
F
V
G
M
S
G
G
G
K
S
T
L
I
N
L
I
P
R
F
Y
D
V
T
S
G
Q
I
L
I
D
G
---
H
N
I
-----
K
--
D
F
--
L
T
G
---
S
--
L
--
R
N
Q
-
I
G
L
-------
V
Q
Q
--
D
-
N
I
L
F
S
D
T
V
K
E
N
I
-
L
L
GR
P
T
A
T
--
D
--
E
E
--
V
V
-----
E
A
--
A
K
M
A
N
-
A
H
D
F
I
M
N
L
PQ
G
Y
D
T
-
E
V
G
E
R
-
G
V
K
L
S
G
G
Q
K
Q
R
L
S
I
A
R
I
F
L
N
N
P
P
I
L
I
L
D
E
A
T
S
A
L
D
-----
L
E
S
E
S
I
I
Q
E
A
L
D
V
L
-
S
-
K
-
D
R
T
T
L
I
V
A
H
R
L
S
T
I
-
T
H
-
A
-
D
K
-
I
V
V
I
E
N
G
H
I
V
E
T
G
T
H
R
E
L
I
A
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
50
PsiBlast_CBE
57.05
32%
-50
- C2 -
2ONJ
4
Y1866_STAAM
B:
[340-565]
----
I
D
I
D
H
V
S
F
Q
Y
N
---
D
N
E
A
P
I
L
K
D
-
I
N
L
S
I
E
K
G
E
T
V
A
F
V
G
M
S
G
G
G
K
S
T
L
I
N
L
I
P
R
F
Y
D
V
T
S
G
Q
I
L
I
D
G
---
H
N
I
-----
K
--
D
F
--
L
T
G
---
S
--
L
--
R
N
Q
-
I
G
L
-------
V
Q
Q
--
D
-
N
I
L
F
S
D
T
V
K
E
N
I
-
L
L
GR
P
T
A
T
--
D
--
E
E
--
V
V
-----
E
A
--
A
K
M
A
N
-
A
H
D
F
I
M
N
L
PQ
G
Y
D
T
-
E
V
G
E
R
-
G
V
K
L
S
G
G
Q
K
Q
R
L
S
I
A
R
I
F
L
N
N
P
P
I
L
I
L
D
E
A
T
S
A
L
D
-----
L
E
S
E
S
I
I
Q
E
A
L
D
V
L
-
S
-
K
-
D
R
T
T
L
I
V
A
H
R
L
S
T
I
-
T
H
-
A
-
D
K
-
I
V
V
I
E
N
G
H
I
V
E
T
G
T
H
R
E
L
I
A
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
68
PsiBlast_CBE
56.22
33%
-62
- C2 -
2FF7
1
A:
[18-231]
------------------
K
P
D
S
P
V
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
---
H
D
L
-----
A
--
L
A
D
-
P
N
----
W
--
L
--
R
R
Q
-
V
G
V
-------
V
L
Q
--
D
N
V
L
L
N
R
-
S
I
I
D
N
I
-
S
L
--
A
-----
N
--
P
G
--
M
S
V
E
K
V
I
Y
A
--
A
K
L
A
G
-
A
H
D
F
I
S
E
L
RE
G
Y
N
T
-
I
V
G
E
Q
-
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
----
E
S
E
H
V
I
M
R
N
M
H
K
I
--
C
-
K
-
G
R
T
V
I
I
I
A
H
R
L
S
T
V
-
K
N
-
A
-
D
R
-
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
78
PsiBlast_CBE
56.18
33%
-61
- C2 -
3B5J
1
A:
[14-227]
------------------
K
P
D
S
P
V
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
A
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
---
H
D
L
-----
A
--
L
A
D
-
P
N
----
W
--
L
--
R
R
Q
-
V
G
V
-------
V
L
Q
--
D
N
V
L
L
N
R
-
S
I
I
D
N
I
-
S
L
--
A
-----
N
--
P
G
--
M
S
V
E
K
V
I
Y
A
--
A
K
L
A
G
-
A
H
D
F
I
S
E
L
RE
G
Y
N
T
-
I
V
G
E
Q
-
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
----
E
S
E
H
V
I
M
R
N
M
H
K
I
--
C
-
K
-
G
R
T
V
I
I
I
A
H
R
L
S
T
V
-
K
N
-
A
-
D
R
-
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
51
PsiBlast_CBE
56.16
32%
-48
- C2 -
2ONJ
4
Y1866_STAAM
A:
[340-565]
----
I
D
I
D
H
V
S
F
Q
Y
N
---
D
N
E
A
P
I
L
K
D
-
I
N
L
S
I
E
K
G
E
T
V
A
F
V
G
M
S
G
G
G
K
S
T
L
I
N
L
I
P
R
F
Y
D
V
T
S
G
Q
I
L
I
D
G
---
H
N
I
-----
K
--
D
F
--
L
T
G
---
S
--
L
--
R
N
Q
-
I
G
L
-------
V
Q
Q
--
D
-
N
I
L
F
S
D
T
V
K
E
N
I
-
L
L
GR
P
T
A
T
--
D
--
E
E
--
V
V
-----
E
A
--
A
K
M
A
N
-
A
H
D
F
I
M
N
L
PQ
G
Y
D
T
-
E
V
G
E
R
-
G
V
K
L
S
G
G
Q
K
Q
R
L
S
I
A
R
I
F
L
N
N
P
P
I
L
I
L
D
E
A
T
S
A
L
D
-----
L
E
S
E
S
I
I
Q
E
A
L
D
V
L
-
S
-
K
-
D
R
T
T
L
I
V
A
H
R
L
S
T
I
-
T
H
-
A
-
D
K
-
I
V
V
I
E
N
G
H
I
V
E
T
G
T
H
R
E
L
I
A
K
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
77
PsiBlast_CBE
55.81
33%
-57
- C2 -
2FFB
1
A:
[18-231]
------------------
K
P
D
S
P
V
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
---
H
D
L
-----
A
--
L
A
D
-
P
N
----
W
--
L
--
R
R
Q
-
V
G
V
-------
V
L
Q
--
D
N
V
L
L
N
R
-
S
I
I
D
N
I
-
S
L
--
A
-----
N
--
P
G
--
M
S
V
E
K
V
I
Y
A
--
A
K
L
A
G
-
A
H
D
F
I
S
E
L
RE
G
Y
N
T
-
I
V
G
E
Q
-
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
----
E
S
E
H
V
I
M
R
N
M
H
K
I
--
C
-
K
-
G
R
T
V
I
I
I
A
H
R
L
S
T
V
-
K
N
-
A
-
D
R
-
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
72
PsiBlast_CBE
55.69
33%
-64
- C2 -
2PMK
1
A:
[14-227]
------------------
K
P
D
S
P
V
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
---
H
D
L
-----
A
--
L
A
D
-
P
N
----
W
--
L
--
R
R
Q
-
V
G
V
-------
V
L
Q
--
D
N
V
L
L
N
R
-
S
I
I
D
N
I
-
S
L
--
A
-----
N
--
P
G
--
M
S
V
E
K
V
I
Y
A
--
A
K
L
A
G
-
A
H
D
F
I
S
E
L
RE
G
Y
N
T
-
I
V
G
E
Q
-
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
E
A
T
S
A
L
D
Y
----
E
S
E
H
V
I
M
R
N
M
H
K
I
--
C
-
K
-
G
R
T
V
I
I
I
A
H
R
L
S
T
V
-
K
N
-
A
-
D
R
-
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
76
PsiBlast_CBE
55.11
33%
-58
- C2 -
2FGK
2
HLYBP_ECOLX
A:
[18-231]
------------------
K
P
D
S
P
V
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
---
H
D
L
-----
A
--
L
A
D
-
P
N
----
W
--
L
--
R
R
Q
-
V
G
V
-------
V
L
Q
--
D
N
V
L
L
N
R
-
S
I
I
D
N
I
-
S
L
--
A
-----
N
--
P
G
--
M
S
V
E
K
V
I
Y
A
--
A
K
L
A
G
-
A
H
D
F
I
S
E
L
RE
G
Y
N
T
-
I
V
G
E
Q
-
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
----
E
S
E
H
V
I
M
R
N
M
H
K
I
--
C
-
K
-
G
R
T
V
I
I
I
A
H
R
L
S
T
V
-
K
N
-
A
-
D
R
-
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
74
PsiBlast_CBE
54.98
33%
-59
- C2 -
2FGK
2
HLYBP_ECOLX
C:
[18-231]
------------------
K
P
D
S
P
V
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
---
H
D
L
-----
A
--
L
A
D
-
P
N
----
W
--
L
--
R
R
Q
-
V
G
V
-------
V
L
Q
--
D
N
V
L
L
N
R
-
S
I
I
D
N
I
-
S
L
--
A
-----
N
--
P
G
--
M
S
VEKVI
Y
A
--
A
K
L
A
G
-
A
H
D
F
I
S
E
L
RE
G
Y
N
T
-
I
V
G
E
Q
-
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
----
E
S
E
H
V
I
M
R
N
M
H
K
I
--
C
-
K
-
G
R
T
V
I
I
I
A
H
R
L
S
T
V
-
K
N
-
A
-
D
R
-
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
73
PsiBlast_CBE
54.76
33%
-60
- C2 -
2FGK
2
D:
[18-231]
------------------
K
P
D
S
P
V
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
---
H
D
L
-----
A
--
L
A
D
-
P
N
----
W
--
L
--
R
R
Q
-
V
G
V
-------
V
L
Q
--
D
N
V
L
L
N
R
-
S
I
I
D
N
I
-
S
L
--
A
-----
N
--
P
G
--
M
S
VEKVI
Y
A
--
A
K
L
A
G
-
A
H
D
F
I
S
E
L
RE
G
Y
N
T
-
I
V
G
E
Q
-
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
----
E
S
E
H
V
I
M
R
N
M
H
K
I
--
C
-
K
-
G
R
T
V
I
I
I
A
H
R
L
S
T
V
-
K
N
-
A
-
D
R
-
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
75
PsiBlast_CBE
53.20
33%
-58
- C2 -
2FGK
2
HLYBP_ECOLX
B:
[18-231]
------------------
K
P
D
S
P
V
I
L
D
N
I
N
L
S
I
K
Q
G
E
V
I
G
I
V
G
R
S
G
S
G
K
S
T
L
T
K
L
I
Q
R
F
Y
I
P
E
N
G
Q
V
L
I
D
G
---
H
D
L
-----
A
--
L
A
D
-
P
N
----
W
--
L
--
R
R
Q
-
V
G
V
-------
V
L
Q
--
D
N
V
L
L
N
R
-
S
I
I
D
N
I
-
S
L
--
A
-----
N
--
P
G
--
M
S
VEKVI
Y
A
--
A
K
L
A
G
-
A
H
D
F
I
S
E
L
RE
G
Y
N
T
-
I
V
G
E
Q
-
G
A
G
L
S
G
G
Q
R
Q
R
I
A
I
A
R
A
L
V
N
N
P
K
I
L
I
F
D
Q
A
T
S
A
L
D
Y
----
E
S
E
H
V
I
M
R
N
M
H
K
I
--
C
-
K
-
G
R
T
V
I
I
I
A
H
R
L
S
T
V
-
K
N
-
A
-
D
R
-
I
I
V
M
E
K
G
K
I
V
E
Q
G
K
H
K
E
L
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
54
PsiBlast_CBE
52.34
39%
-59
- C2 -
1VCI
1
?
A:
[10-208]
---
M
V
E
V
K
L
E
N
L
T
K
R
F
G
--
N
F
T
A
V
N
K
--
L
N
L
T
I
K
D
G
E
F
L
V
L
L
G
P
S
G
C
G
K
T
T
T
L
R
M
I
A
G
L
E
E
P
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E
G
R
I
-
Y
F
G
---
D
-------
R
--
D
V
T
-
Y
L
P
---
P
--
K
--
D
R
N
-
I
S
M
-------
V
F
Q
--------
H
M
T
V
Y
E
N
I
-
A
F
--
P
L
----
K
KF
P
K
---
D
-----
E
I
--
D
K
R
V
R
W
A
A
E
L
L
Q
-----
I
E
E
-
L
L
N
R
Y
-
P
A
Q
L
S
G
G
Q
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Q
R
V
A
V
A
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A
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L
L
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K
L
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Q
K
L
K
-
V
-----
T
T
I
Y
V
T
H
D
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------