@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0752: (2016-03-18 )
MSVLNIEGAKLSYQKVGQGPILIFIPGANGTGDIFLPLAEQLKTSFSVVMVDRRGYGDSELTAAIPERASHAYDDYRVTRDAADIAALAKALSDVPVYILGSSSGSIVAMHVLKNHPEVVKKIAFHEPPINTFLPDSEMWQEANEKIVQTALTKNMAEAMQLFGETLHIAPIDAESMSKPAVTIDEVTKDSTTQQMKYWFTYEIRQYTSSNISLDDFKPYVHQITLLNGTDSKGSFPQDVNAFIAKQLGLTIVDIPGGHLGYIQKPAGFAKVLLSIWG
Atome Classification :
(20 SA)
------------......-...10......----.--.-20.........30.---..-.....40.-.-......50........60........70........80........90........100.......110.......120-....------...130---.....--.--..140--.--..-....-.150-.---..--...-.---------..160...--..-----..-170.--..-.....180..------....-.190.........200...-----.....-.210.-.-.---.....220....-----....230.......240....-.-..-250.....-..260.......270......-----
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
------------M
S
V
L
NI-EGAKL
S
Y
Q
KVG----Q--G-
P
-
I
L
I
F
IPGANGTG---D
I
-
F
L
P
L
A
E
Q
L
-K-TS
F
S
V
V
M
V
DRRGYG
D
S
E
L
T
A
A
I
P
E
R
A
SHAYDD
Y
R
VTR
D
A
A
D
I
A
A
L
A
K
A
LSDV
P
V
Y
I
L
GSSSG
S
I
V
A
M
H
V
L
KN
H
P
E
V
V
K
K
-
I
AFH------EPPIN----TFLP
D
--
S
--
E
M
W
Q
---
E
--
A
N
-
E
K
I
V
-
Q
T
---
A
---
L
T
--
K
N
M
-
A
---------
E
A
M
Q
L
F
GE--T
L
-----
H
I-AP-I--
D
A
-
E
SMSKP
A
V
T
I
------
D
EVT-KD--STT
Q
Q
M
K
Y
W
F
--
T
Y
E
-----
I
R
Q
YT-SS-NI-
S
-
L
---
D
D
F
K
P
Y
V
-
H
Q
I
T
-----
L
LNGTDSKGSF
P
Q
D
V
N
A
F
I
A
K
-Q-LG-
L
T
I
V
DIPG-GHLGYIQKP
A
G
F
A
K
V
L
L
S
IWG-----
97
Fugue
79.90
20%
-69
- C1 -
3WZM
1
?
A:
[15-278]
--------M
R
T
R
S
T
I
S
T
P
-
N
G
I
T
W
Y
Y
E
Q
E
G
----
T
--
G
-
P
-
D
V
V
L
V
P
D
G
L
G
E
C
---
Q
M
-
F
D
S
S
V
S
Q
I
A
A
-
Q
G
F
R
V
T
T
F
D
M
P
G
M
S
R
S
------
A
K
A
P
P
E
T
Y
T
E
V
T
A
Q
K
L
A
S
Y
V
I
S
V
L
D
A
L
D
I
K
H
A
T
V
W
G
C
A
S
G
A
S
T
V
V
A
L
L
L
G
Y
P
D
R
I
R
N
-
A
M
C
H
------
E
L
P
-------------------
T
---
K
--
L
L
-
D
H
L
S
-
N
T
---
A
---
V
L
--
E
D
E
-
E
---------
I
S
K
I
L
A
N
V
--
M
L
-----
N
D
-
V
S
-
G
--
G
S
-
E
A
W
Q
A
M
G
---------
D
E
V
H
-
A
R
--
L
H
K
N
Y
P
V
W
A
R
--
G
Y
P
-----
R
T
I
P
P
-
S
A
-
P
V
K
D
-
L
---
E
A
L
R
G
K
P
-
L
D
W
T
-----
V
G
A
A
T
P
T
E
S
F
F
D
N
I
V
T
A
T
K
A
-----
G
-
V
N
I
G
L
L
P
G
-
M
H
F
P
Y
V
S
H
P
D
V
F
A
K
Y
V
V
E
T
T
Q
K
H
L--
70
HHSearch
77.02
19%
-75
* C1 *
3OM8
2
?
A:
[10-265]
---------------
A
T
S
-
D
G
A
S
L
A
Y
R
L
D
G
----
A
AE
K
-
P
-
L
L
A
L
S
N
S
I
G
T
T
L
---
H
M
-
W
D
A
Q
L
P
A
L
-
T
-
R
H
F
R
V
L
R
Y
D
A
R
G
H
G
A
S
S
V
P
----------
P
G
P
Y
T
L
A
R
L
G
E
D
V
L
E
L
L
D
A
L
E
V
R
R
A
H
F
L
G
L
S
L
G
G
I
V
G
Q
W
L
A
L
H
A
P
Q
R
I
E
R
-
L
V
L
A
------
N
T
S
A
W
----
L
G
P
A
------
A
Q
W
D
---
E
------
R
I
A
-
A
V
---
L
---
Q
A
--
E
D
M
-
S
---------
E
T
A
A
G
F
L
G
--
N
W
-----
F
P
-
P
A
-
L
--
L
E
-
R
-
A
E
P
V
V
-----------
E
R
F
R
A
--
M
L
M
A
T
N
R
H
G
L
--
A
G
S
-----
F
A
A
V
---
R
-
D
T
-
D
L
R
---
A
Q
L
A
R
I
E
-
R
P
T
L
-----
V
I
A
G
A
Y
D
T
V
T
A
-
A
S
H
G
E
L
I
A
A
S
I
-
A
G
-
A
R
L
V
T
L
P
A
-
V
H
L
S
N
V
E
F
P
Q
A
F
E
G
A
V
L
S
F
L
G
-----
75
HHSearch
75.95
16%
-69
- C1 -
2XUA
-
?
A:
[5-263]
-------------
P
Y
A
A
V
-
N
G
T
E
L
H
Y
R
I
D
G
ERH
G
N
--
A
-
P
-
W
I
V
L
S
N
S
L
G
T
D
L
---
S
M
-
W
A
P
Q
V
A
A
L
-
S
-
K
H
F
R
V
L
R
Y
D
T
R
G
H
G
H
S
E
A
P
----------
K
G
P
Y
T
I
E
Q
L
T
G
D
V
L
G
L
M
D
T
L
K
I
A
R
A
N
F
C
G
L
S
M
G
G
L
T
G
V
A
L
A
A
R
H
A
D
R
I
E
R
-
V
A
L
C
------
N
T
A
A
R
----
I
G
S
P
E
------
V
W
V
---
P
------
R
A
V
-
K
A
---
R
----
T
--
E
G
M
-
H
---------
A
L
A
D
A
V
L
P
--
R
W
-----
F
T
-
A
D
Y
M
--
E
R
E
P
V
V
L
A
M
I
-----------
R
D
-
V
---
F
V
H
T
D
K
E
G
Y
---
A
S
N
-----
C
E
A
I
D
-
A
--
A
D
-
L
-
R
---
P
E
A
P
G
I
K
-
V
P
A
L
-----
V
I
S
G
T
H
D
L
A
A
T
-
P
A
Q
G
R
E
L
A
Q
-
A
I
A
G
-
A
R
Y
V
E
L
D
A
-
S
H
I
S
N
I
E
R
A
D
A
F
T
K
T
V
V
D
F
L
T
-----
88
HHSearch
74.70
18%
-75
- C1 -
3KXP
1
AAMHY_RHILO
A:
[53-313]
---------------
V
D
I
-
G
R
I
T
L
N
V
R
E
K
G
----
S
--
G
-
P
-
L
M
L
F
F
H
G
I
T
S
N
S
---
A
V
-
F
E
P
L
M
I
R
L
-
S
-
D
R
F
T
T
I
A
V
D
Q
R
G
H
G
L
S
D
K
P
E
----------
T
G
Y
E
A
N
D
Y
A
D
D
I
A
G
L
I
R
T
L
A
R
G
H
A
I
L
V
G
H
S
L
G
A
R
N
S
V
T
A
A
A
K
Y
P
D
L
V
R
S
-
V
V
A
I
------
D
F
T
P
Y
----
I
E
T
E
A
--
L
--
D
A
L
E
---
A
--
R
V
-
N
A
G
S
-
Q
L
---
F
---
E
----
D
I
-
K
----------
A
V
E
A
Y
L
A
--
G
R
-----
Y
P
-
N
--
I
--
P
A
-
D
A
I
-
R
I
R
-
A
--------
E
S
G
-
Y
Q
--
P
V
D
G
G
L
R
P
L
A
S
S
A
A
M
-----
A
Q
T
A
R
-
G
L
-
R
S
-
D
L
V
---
P
A
Y
R
D
V
T
-
K
P
V
L
-----
I
V
R
G
E
S
S
K
L
V
S
A
-
A
A
L
A
K
T
S
R
L
R
-
P
D
-
L
P
V
V
V
V
P
G
A
D
H
Y
V
N
E
V
S
P
E
I
T
L
K
A
I
T
N
F
I
D
-----
90
HHSearch
73.93
17%
-82
- C1 -
3WZM
1
?
A:
[21-275]
--------------
I
S
T
P
-
N
G
I
T
W
Y
Y
E
Q
E
G
----
T
--
G
-
P
-
D
V
V
L
V
P
D
G
L
G
E
C
---
Q
M
-
F
D
S
S
V
S
Q
I
-
A
A
Q
G
F
R
V
T
T
F
D
M
P
G
M
S
R
S
A
K
A
P
P
------
E
T
Y
T
E
V
T
A
Q
K
L
A
S
Y
V
I
S
V
L
D
A
L
D
I
K
H
A
T
V
W
G
C
A
S
G
A
S
T
V
V
A
L
L
L
G
Y
P
D
R
I
R
N
-
A
M
C
H
------
E
L
P
T
K
----
L
L
D
H
L
--
S
---
N
T
A
---------------
V
---
L
---
E
D
--
E
E
I
-
S
---------
K
I
L
A
N
V
M
L
--
N
D
-----
V
S
-
G
G
-
S
-----
E
A
W
Q
A
M
G
-
D
---------
E
V
-
H
A
--
R
L
H
K
N
Y
P
V
W
A
--
R
G
Y
-----
P
R
T
I
--
P
P
-
S
A
-
P
-
V
---
K
D
L
E
A
L
R
G
K
P
L
D
-----
W
T
V
G
A
A
T
P
T
E
S
F
F
D
--
N
I
V
T
A
T
K
-
A
G
-
V
N
I
G
L
L
P
G
-
M
H
F
P
Y
V
S
H
P
D
V
F
A
K
Y
V
V
E
T
T
Q
-----
69
HHSearch
73.62
15%
-77
- C1 -
3OOS
6
?
A:
[6-278]
-------------
N
I
I
K
T
-
P
R
G
K
F
E
Y
F
L
K
G
----
E
--
G
-
P
-
P
L
C
V
T
H
L
Y
S
E
Y
N
---
D
N
-
G
N
T
F
A
N
P
F
-
T
-
D
H
Y
S
V
Y
L
V
N
L
K
G
C
G
N
S
D
S
A
K
--------
N
D
S
E
Y
S
M
T
E
T
I
K
D
L
E
A
I
R
E
A
L
Y
I
N
K
W
G
F
A
G
H
S
A
G
G
M
L
A
L
V
Y
A
T
E
A
Q
E
S
L
T
K
-
I
I
V
G
------
G
A
A
A
S
----
K
E
Y
A
S
--
H
--
K
D
S
I
YCS
K
NV
K
F
-
N
R
I
V
-
S
I
M
N
A
L
---
N
D
--
D
S
T
V
Q
---------
E
E
R
K
A
L
S
R
--
E
W
-----
A
L
M
S
F
-
Y
--
S
E
-
E
K
L
E
E
A
L
-----------
K
--
L
P
--
N
S
G
K
T
V
G
N
R
L
--
N
-
Y
-----
F
R
Q
V
E
-
Y
K
-
D
Y
-
D
V
R
---
Q
K
L
K
F
V
K
-
I
P
S
F
-----
I
Y
C
G
K
H
D
V
Q
C
P
-
Y
I
F
S
C
E
I
A
N
-
L
I
P
N
-
A
T
L
T
K
F
E
E
S
N
H
N
P
F
V
E
E
I
D
K
F
N
Q
F
V
N
D
T
L
------
85
HHSearch
72.50
15%
-79
- C1 -
1IUP
3
?
A:
[9-271]
--------------
S
I
L
A
-
A
G
V
L
T
N
Y
H
D
V
G
----
E
--
G
-
Q
-
P
V
I
L
I
H
G
S
G
P
G
V
S
A
Y
A
N
-
W
R
L
T
I
P
A
L
-
S
-
K
F
Y
R
V
I
A
P
D
M
V
G
F
G
F
T
D
R
P
E
---------
N
Y
N
Y
S
K
D
S
W
V
D
H
I
I
G
I
M
D
A
L
E
I
E
K
A
H
I
V
G
N
A
F
G
G
G
L
A
I
A
T
A
L
R
Y
S
E
R
V
D
R
-
M
V
L
M
------
G
A
A
G
T
----
R
F
D
V
T
--
E
---
G
L
N
---
A
--
V
W
-
G
-
Y
T
-
P
S
---
I
---
E
----
N
M
-
R
---------
N
L
L
D
I
F
A
Y
DR
S
L
-----
V
T
-
D
E
-
L
--
A
R
-
L
R
Y
E
A
S
I
--------------
Q
P
--
G
F
Q
E
S
F
S
S
M
F
--
P
E
P
-----
R
Q
R
W
I
D
A
L
-
A
S
-
S
-
D
---
E
D
I
K
T
L
P
-
N
E
T
L
-----
I
I
H
G
R
E
D
Q
V
V
P
-
L
S
S
S
L
R
L
G
E
-
L
I
D
R
-
A
Q
L
H
V
F
G
R
C
G
H
W
T
Q
I
E
Q
T
D
R
F
N
R
L
V
V
E
F
F
N
-----
83
HHSearch
72.49
13%
-82
- C1 -
3WI7
3
DHAA_AGRFC
A:
[24-299]
--------------
D
V
P
A
-
F
G
L
Q
I
H
T
V
E
H
G
----
S
--
G
-
A
-
P
I
V
F
L
H
G
N
P
T
S
S
---
Y
L
-
W
R
H
I
F
R
R
L
-
H
-
G
H
G
R
L
L
A
V
D
L
I
G
Y
G
Q
S
S
K
P
----------
D
I
E
Y
T
L
E
N
Q
Q
R
Y
V
D
A
W
F
D
A
L
D
L
R
N
V
T
L
V
L
Q
D
Y
G
A
A
F
G
L
N
W
A
S
R
N
P
D
R
V
R
A
-
V
A
F
F
------
E
P
V
L
R
----
N
I
D
S
V
--
D
LS
P
E
F
V
---
T
--
R
R
-
A
K
L
R
Q
P
G
---
E
G
E
I
F
V
--
Q
Q
E
-
N
---------
R
F
L
T
E
L
F
P
--
W
F
-----
F
L
-
T
P
-
L
--
A
P
-
E
D
L
R
Q
Y
Q
-----------
T
P
-
F
P
TP
H
S
R
K
A
I
L
A
G
P
--
R
N
L
PVDGE
P
A
S
T
V
-
A
F
L
E
Q
-
A
-
V
---
N
W
L
N
T
S
D
-
T
P
K
L
-----
L
L
T
F
K
P
G
F
L
L
-
T
D
A
I
L
K
W
S
Q
V
T
I
-
R
N
-
L
E
I
E
A
A
G
A
G
I
H
F
V
Q
E
E
Q
P
E
T
I
A
R
L
L
D
A
W
L
T
-----
94
Fugue
72.34
17%
-75
- C1 -
1QTR
-
PIP_SERMA
A:
[4-317]
LRGLY
P
P
L
A
A
Y
D
S
G
W
L
D
T
G
D
G
H
R
I
Y
W
E
L
S
G
NP--
N
--
G
-
K
-
P
A
V
F
I
H
G
G
P
G
G
G
---
I
S
-
P
H
H
R
Q
L
F
D
-
P
-
E
R
Y
K
V
L
L
F
D
Q
R
G
C
G
R
S
R
--------
P
H
A
S
L
D
N
N
T
T
W
H
L
V
A
D
I
E
R
L
R
E
M
A
G
V
E
Q
W
L
V
F
G
G
S
W
G
S
T
L
A
L
A
Y
A
Q
T
H
P
E
R
V
S
E
-
M
V
L
R
GIFTLR
K
Q
R
L
H
----
W
Y
Y
Q
D
G
A
S
--
R
F
F
P
---
E
--
K
W
-
E
R
V
L
-
S
I
---
L
---
S
D
--
D
E
R
-
K
---------
D
V
I
A
A
Y
R
Q
--
R
L
T
SAD
P
Q
V
-
Q
L
-
E
--
A
A
-
K
L
W
S
V
W
E
G
E
T
VTLLPS
R
-
E
S
-
A
S
--
F
G
E
D
D
F
A
L
A
F
--
A
R
I
-----
E
N
H
Y
F
-
T
H
-
L
G
-
F
-
L
ESD
D
Q
L
L
R
N
V
-
P
L
I
R
H
I
P
A
V
I
V
H
G
R
Y
D
M
A
C
Q
V
Q
N
A
W
D
L
A
K
A
-
W
-
P
E
-
A
E
L
H
I
V
E
G
-
A
--
G
H
S
Y
D
E
P
G
I
L
H
Q
L
M
I
A
T
D
R
F
A
G
K
1
PsiBlast_PDB
71.31
29%
-116
- C1 -
3QYJ
-
?
A:
[8-126]
-------------
T
I
V
D
T
-
T
E
A
R
I
N
L
V
K
A
G
----
H
--
G
-
A
-
P
L
L
L
L
H
G
Y
P
Q
T
H
---
V
M
-
W
H
K
I
A
P
L
L
-
A
-
N
N
F
T
V
V
A
T
D
L
R
G
Y
G
D
S
S
R
P
A
S
V
P
H
H
I
N
Y
S
---
K
R
V
M
--
A
Q
D
Q
V
E
V
M
S
K
L
G
Y
E
Q
F
Y
V
V
G
H
D
R
G
A
R
V
A
H
R
L
A
L
D
H
P
H
R
V
K
K
-
L
A
L
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
70.93
36%
-112
- C1 -
2OCG
2
BPHL_HUMAN
A:
[9-122]
-----------------
V
-
N
G
V
Q
L
H
Y
Q
Q
T
G
----
E
--
G
-
D
H
A
V
L
L
L
P
G
M
L
G
S
G
---
E
T
D
F
G
P
Q
L
K
N
L
N
K
-
K
L
F
T
V
V
A
W
D
P
R
G
Y
G
H
S
R
----
P
P
D
R
D
F
P
A
--
D
F
-
F
E
R
D
A
K
D
A
V
D
L
M
K
A
L
K
F
K
K
V
S
L
L
G
W
S
D
G
G
I
T
A
L
I
A
A
A
K
Y
P
S
Y
I
H
K
-
M
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
70.59
36%
-110
- C1 -
2OCI
2
BPHL_HUMAN
A:
[9-122]
-----------------
V
-
N
G
V
Q
L
H
Y
Q
Q
T
G
----
E
--
G
-
D
H
A
V
L
L
L
P
G
M
L
G
S
G
---
E
T
D
F
G
P
Q
L
K
N
L
N
K
-
K
L
F
T
V
V
A
W
D
P
R
G
Y
G
H
S
R
----
P
P
D
R
D
F
P
A
--
D
F
-
F
E
R
D
A
K
D
A
V
D
L
M
K
A
L
K
F
K
K
V
S
L
L
G
W
S
D
G
G
I
T
A
L
I
A
A
A
K
Y
P
S
Y
I
H
K
-
M
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
70.38
24%
-86
- C1 -
4L0C
2
?
A:
[20-194]
-----------------------------
G
----
T
--
G
-
S
-
P
L
L
L
I
P
G
I
T
S
P
A
---
V
T
-
W
G
F
V
A
E
R
L
-
A
-
K
Y
F
D
V
H
V
V
D
V
R
G
R
G
L
S
E
S
G
D
L
----------
D
Y
S
L
D
A
M
A
D
D
L
V
A
L
A
Q
R
M
E
G
--
V
V
V
L
G
H
A
M
G
A
R
I
A
I
R
A
A
R
K
D
S
Q
V
F
S
R
-
L
I
L
V
------
D
P
P
V
S
GPGR
R
P
Y
P
A
--
K
--
W
S
W
Y
---
A
--
E
S
-
I
R
L
A
-
Q
R
---
G
---
C
T
--
A
M
E
-
M
RSYCPTWT
D
E
Q
I
E
L
R
A
E
--
W
L
-----
H
T
-
C
Q
-
Y
--
T
A
-
V
K
T
A
F
D
G
F
H
T
------
D
D
I
H
-
T
D
-----------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
70.37
35%
-110
- C1 -
2OCL
1
BPHL_HUMAN
A:
[9-122]
-----------------
V
-
N
G
V
Q
L
H
Y
Q
Q
T
G
----
E
--
G
-
D
H
A
V
L
L
L
P
G
M
L
G
S
G
---
E
T
D
F
G
P
Q
L
K
N
L
N
K
-
K
L
F
T
V
V
A
W
D
P
R
G
Y
G
H
S
R
----
P
P
D
R
D
F
P
A
--
D
F
-
F
E
R
D
A
K
D
A
V
D
L
M
K
A
L
K
F
K
K
V
S
L
L
G
W
A
D
G
G
I
T
A
L
I
A
A
A
K
Y
P
S
Y
I
H
K
-
M
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
70.36
36%
-110
- C1 -
2OCK
1
BPHL_HUMAN
A:
[9-122]
-----------------
V
-
N
G
V
Q
L
H
Y
Q
Q
T
G
----
E
--
G
-
D
H
A
V
L
L
L
P
G
M
L
G
S
G
---
E
T
D
F
G
P
Q
L
K
N
L
N
K
-
K
L
F
T
V
V
A
W
D
P
R
G
Y
G
H
S
R
----
P
P
D
R
D
F
P
A
--
D
F
-
F
E
R
D
A
K
D
A
V
D
L
M
K
A
L
K
F
K
K
V
S
L
L
G
W
S
N
G
G
I
T
A
L
I
A
A
A
K
Y
P
S
Y
I
H
K
-
M
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
89
HHSearch
69.99
16%
-88
- C1 -
3P2M
-
?
A:
[67-328]
-----------------
V
-
Q
A
G
A
I
S
A
L
R
W
G
G---
S
--
A
-
P
-
R
V
I
F
L
H
G
G
G
Q
N
A
---
H
T
-
W
D
T
V
I
V
G
L
----
G
E
P
A
L
A
V
D
L
P
G
H
G
H
S
A
W
R
E
---------
D
G
N
Y
S
P
Q
L
N
S
E
T
L
A
P
V
L
R
E
L
A
P
G
A
E
F
V
V
G
M
S
L
G
G
L
T
A
I
R
L
A
A
M
A
P
D
L
V
G
E
-
L
V
L
V
------
D
V
T
P
S
----
A
L
Q
R
H
--
A
--
E
-
L
T
---
A
-----------------------
E
R
E
-
F
---------
P
S
F
Q
A
M
L
D
--
L
T
-----
I
A
-
A
A
-
P
HR
D
V
-
K
S
L
R
R
G
V
F
----------
H
N
-
S
R
--
R
L
D
N
G
N
W
V
W
R
--
Y
D
A
-----
I
R
T
F
G
-
D
F
-
A
G
-
L
-
W
---
D
D
V
D
A
L
S
-
A
P
I
T
-----
L
V
R
G
G
S
S
G
F
V
T
D
-
Q
D
T
A
E
L
H
R
R
A
-
T
H
F
R
G
V
H
I
V
E
K
S
G
H
S
V
Q
S
D
Q
P
R
A
L
I
E
I
V
R
G
V
L
D
-----
8
PsiBlast_PDB
69.06
21%
-84
- C1 -
4O08
4
?
A:
[40-225]
---------------
I
N
V
-
N
G
V
N
L
H
Y
I
S
K
G
----
Q
--
G
-
E
-
L
M
L
F
L
H
G
F
P
D
F
S
---
H
I
-
W
R
H
Q
I
D
E
F
-
S
-
N
D
F
H
T
V
A
L
D
L
R
G
Y
N
L
S
E
K
P
S
G
L
--------
E
S
Y
E
I
D
V
L
V
E
D
I
R
Q
V
I
E
G
L
G
Y
S
S
C
T
L
V
V
H
D
W
G
A
G
I
G
W
T
F
A
Y
R
Y
P
E
Y
V
Q
K
L
I
A
F
N
------
G
P
H
P
Y
----
T
F
M
----
R
--
E
L
R
T
---
N
--
K
N
-
Q
Q
K
A
-
S
E
---
Y
---
M
K
--
W
F
Q
-
K
---------
Q
E
V
Q
D
Y
M
E
--
R
D
-----
N
F
-
S
G
-
L
---
R
-
K
L
V
I
D
P
G
V
K
K
------
G
Y
L
T
-
A
D
--
D
V
Q
A
Y
M
N
S
W
------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
68.84
24%
-110
- C1 -
4INZ
2
?
A:
[23-148]
---------------
I
N
V
-
N
G
V
N
L
H
Y
I
S
K
G
----
Q
--
G
-
E
-
L
M
L
F
L
H
G
F
P
D
F
S
---
H
I
-
W
R
H
Q
I
D
E
F
-
S
-
N
D
F
H
T
V
A
L
D
L
R
G
Y
N
L
S
E
K
P
S
G
L
--------
E
S
Y
E
I
D
V
L
V
E
D
I
R
Q
V
I
E
G
L
G
Y
S
S
C
T
L
V
V
H
D
W
G
A
G
I
G
W
T
F
A
Y
R
Y
P
E
Y
V
Q
K
L
I
A
F
N
------
G
P
H
P
Y
----
T
F
M
R
E
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
80
HHSearch
68.62
15%
-71
- C1 -
1WOM
11
RSBQ_BACSU
A:
[4-268]
---------------
M
T
S
-
I
L
S
R
N
H
V
K
V
K
G
----
S
--
G
K
A
-
S
I
M
F
A
P
G
F
G
C
D
Q
---
S
V
-
W
N
A
V
A
P
A
F
-
E
-
E
D
H
R
V
I
L
F
D
Y
V
G
S
G
H
S
D
L
R
A
Y
D
------
L
N
R
Y
Q
T
L
D
G
Y
A
Q
D
V
L
D
V
C
E
A
L
D
L
K
E
T
V
F
V
G
H
S
V
G
A
L
I
G
M
L
A
S
I
R
R
P
E
L
F
S
H
-
L
V
M
V
------
G
P
S
P
C
----
Y
L
N
D
P
--
P
--
E
Y
Y
G
---
G
--
F
E
E
E
Q
L
L
-
G
L
---
L
---
E
M
M
E
K
N
Y
-
I
---------
G
W
A
T
V
F
A
A
--
T
V
-----
L
N
-
Q
--
P
--
D
R
-
P
E
I
K
E
E
L
--------------
E
S
--
R
F
C
S
T
D
-
P
V
I
--
A
R
Q
-----
F
A
K
A
A
-
F
F
-
S
D
-
H
-
R
---
E
D
L
S
K
V
T
-
V
P
S
L
-----
I
L
Q
C
A
D
D
I
I
A
-
P
A
T
V
G
K
Y
M
H
Q
-
H
L
P
Y
-
S
S
L
K
Q
M
E
A
R
G
H
C
P
H
M
S
H
P
D
E
T
I
Q
L
I
G
D
Y
L
K
-----
11
PsiBlast_PDB
67.94
24%
-113
- C1 -
4IO0
1
?
A:
[23-140]
---------------
I
N
V
-
N
G
V
N
L
H
Y
I
S
K
G
----
Q
--
G
-
E
-
L
M
L
F
L
H
G
F
P
D
F
S
---
H
I
-
W
R
H
Q
I
D
E
F
-
S
-
N
D
F
H
T
V
A
L
D
L
R
G
Y
N
L
S
E
K
P
S
G
L
--------
E
S
Y
E
I
D
V
L
V
E
D
I
R
Q
V
I
E
G
L
G
Y
S
S
C
T
L
V
V
H
D
W
G
A
G
I
G
W
T
F
A
Y
R
Y
P
E
Y
V
Q
K
L
I
A
F
N
------
G
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------