@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0830: (2016-03-18 )
VKTIDMKYLRLLAKEYPTIAKTATEIINLEAIMNLPKGTEHFLSDVHGEYSAFEQVLRNGSGVVKRKIRDIFGAELDDAEINSLSTLIYYPEEKMDLIASETEDLHAWYRTTLFRLIELCQYVASKYTRSKVRKAMPEDFAYILEELLHENYNEDDKKLYYEEILQHIISLGRAEEFISALSLLIQQLVVDHLHIVGDVYDRGPYPDKIMDTLMNYHSLDFQWGNHDILWMGAASGSRVCAANVIRISARYLNLDILEDSYGISLRPLALFADEVYKDDPCTYFQPKNEENINYSNAEITQIARMHKAISIIQFKLEGEIIKRRKEFDMNHRLLLQFIDYKKGTIQLKGKEYQLLDNHFPTINPENPYELTDAERELIGKITAAFKNCRRLQKHVQFLYSKGSMFLTYNGNLLYHGCIPLHKDGTFMEMKLRGEKYAGRALLEQFEILTREAYVRPTGTKEKKYACDIVWYLWTGAISSLFGKSEMTTFERYFVAEKETHTEEKNPYYKLRNNELICKQILEEFELDGECGHIINGHTPVKEGKGESPIKASGKMLVIDGGFAKAYHKETNLAGYTLLFNSYGLQLVSHQPFTTKEDAIKNETDILSTRQVIEMEINRKRVRDTDIGAKLSEQAEDLKLLLDAYRNGLLHENR
Atome Classification :
(20 SA)
----.........10......-----------..--20.-....-.-..30...----.-....40....-..-..50-.------........60........70........80........90.....----...100.......110..-......120--------------------....-.-----...130--......-...140.......150---.......-..160.....------..170..------------------.......180...-----..-------.----.-----190--..-.......200....-----...210.....--------.---.220...-....230---------.-...-------...240-...------...---..250.......260......-.270--------..-----------..--------...280--.---.-...------------..-------..290.----.----.....300.-----.-.....--------310---....-----...320.......330..--.----.----------------....340.---.-.....350----........360--....--....370.......380-........390.......400-........410...--.....420.......-430.......440.......--450.......460.......470.......480.......490.......500..-.....510........520--........530..----------.....540----------.........550....-.--..560.-.......570.......580------.......590.-----....-..600.......610.--------------......620.......630.......640.......650.---------------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----VKTI
D
M
K
Y
L
R
L
L
A
K
EYP-----------
T
I
--
A
K
T
-
A
T
E
I
-
I
-
N
L
E
A
I
MN----L-PK
G
T
E
H
F
L
S
D
-VH-G
E
Y
--
S
------
A
F
E
Q
V
L
RNGS
G
V
V
K
R
K
I
R
D
I
FGAELDDAEINS
L
S
T
L
I
YYP
E
E
K
M
D
----
L
I
ASE
T
E
D
L
H
A
W
Y
R
T
-
T
L
-
F
R
L
I
E
L
C
Q
---------------------
Y
V
A
S
-
K
-----
Y
T
R
S
----
K
V
R
K
AM-
P
E
D
F
A
Y
I
L
E
E
L
L
HE-----NYNE
D
D
K
-
K
L
Y
Y
E
E
I
L
Q
H
------
I
I
S--LG------------------
R
A
E
E
F
I
S
A
L
S
L
L
I
-----
Q
Q
-------
L
----
V
-----
V
----
D
H
-
L
H
I
V
G
D
V
YDRGPY
P
-----
D
K
I
M
D
T
L
M
NYH--------S---
L
D
F
QWGN-H
D
I
L
W
M
G---------A-ASG-------S
R
V
C
A
--
A
N
V
------
I
R
I
---
S
A
R
Y
L
N
L
D
I
LEDSYG
I
S
L
R
P
L
-
A
L
F
A
--------
D
E
-----------VY--------KDDP----C---T-YFQ------------PK-------NEENIN----Y----S
N
A
E
I
T
Q
I
A
-----
R
-
M
H
K
A
I
--------
S
I
I
---
Q
F
K
L-----E
G
E
I
I
K
R
R
K
EFD
M
N
-
H
R
L
--
L
----
L
----------------
Q
F
IDYKK
G
---
T
-
I
Q
LKGK
E
-----
Y
Q
L
L
D
NHFPT---INPE--NPYEL
T
D
A
E
R
E
L
I
G
K
I
--
T
A
A
F
K
N
C
R
R
L
Q
K
H
V
Q
F
L
Y
SK--G
S
M
F
L
T
YNG
N
-
L
L
Y
--HGCIPLHKDG
T
F
M
E
M
-
K
LRGE
K
Y
A
G
R
A
L
L
E
Q
F
E
I
L
T
--
R
EAYVRPTGTKE
K
K
Y
A
C
D
I
V
W
Y
L
W
T
G
A
I
S
S
L
FGKSE
M
T
T
F
E
R
Y
F
VAEKETHTEEK-NP
Y
Y
K
L-RN
N
E
L
I
C
K
Q
I
L
---
E
EFELDGECGHII----------NGHTPV------------KEGKGESPIKASG
K
M
L
-
V
--IDG-G
F
-
A
K
A
Y
HKETNLA
G
Y
T
L
L
F
NSY------
G
L
Q
L
VSHQPFT-----T
K
E
D
-AIKNE
T
D
I
L
S
T
R
Q
V
I
E
--------------
M
EINRKRVRDTDIG
A
K
L
S
E
Q
A
E
D
L
K
L
L
L
D
A
Y
RNGLLHENR---------------------------------------------------
31
Fugue
87.74
20%
-41
- C1 -
4GA6
3
AMPPA_THEKO
A:
[1-493]
-----
M
K
A
K
I
R
I
L
D
M
F
S
G
R
Y
T
-----------
V
L
I
N
E
E
D
-
A
K
E
A
K
L
-
H
P
D
D
L
V
K
----
I
-
E
A
G
K
K
A
V
Y
G
S
-
V
A
-
L
S
-------------
N
L
V
G
K
G
E
V
G
I
S
R
D
V
L
D
L
H
N
---------------
F
S
E
G
E
T
V
S
----
V
I
P
A
G
T
P
----------------
E
S
V
R
---------------------
Y
I
K
K
-
K
-----
M
H
G
E
----
K
L
R
----
K
V
E
I
E
A
I
V
R
D
I
V
------------
D
R
-
K
L
R
D
I
E
I
S
S
F
------
V
T
A
--
L
E
------------------
I
N
G
L
D
M
D
E
I
A
A
L
T
-----
I
A
-------
M
----
A
-----
E
----------
T
G
D
M
L
D
I
D
R
K
P
-----------
I
M
D
V
H
--------
S
---
I
G
G
V
P
G
N
K
T
N
I
L
V
V
P
---------
I
-
V
A
A
-------
A
G
L
-----
T
I
------
P
K
T
---
S
S
R
A
I
T
------
S
A
A
G
T
A
D
V
V
-
E
V
F
A
--------
D
----------------------------------------------------------------
V
S
----
F
----
S
L
D
E
I
K
R
I
V
-----
E
-
K
V
G
A
C
--------
L
V
W
---
G
G
A
L
NLA
P
A
D
D
I
T
I
K
A
E
R
A
L
S
I
D
P
T
G
L
--
M
----
L
----------------
A
S
I
M
S
K
K
Y
---
A
-
M
---
G
S
Q
-----
Y
V
L
I
D
--
I
P
T
G
KG
V
K
V
E
--
T
V
E
E
A
R
S
L
A
R
D
F
I
---------
E
L
G
K
R
L
G
Q
Y
V
E
V
A
I
T
Y
--
G
G
Q
P
I
---
G
H
-
T
V
----
G
P
A
L
E
A
R
E
A
L
S
A
L
M
-
T
G
K
G
P
G
S
L
I
E
K
A
T
G
L
A
G
I
L
L
--
E
M
G
G
V
A
P
A
G
T
-------------------------------------------------------
G
K
K
M
A
K
E
I
L
---
E
S
G
K
A
W
E
K
M
K
E
I
I
----------
E
A
Q
G
G
D
------------
P
N
I
K
P
E
E
I
P
I
G
D
----------------
K
T
Y
T
F
T
A
A
T
S
G
Y
V
T
A
I
D
N
R
------
A
I
T
A
I
A
R
A
A
G
A
-----
P
E
D
K
-
G
A
G
I
E
L
Y
V
K
V
G
E
K
V
K
E
----------------------
G
D
P
L
F
T
I
H
A
E
H
E
A
R
L
D
Q
A
I
V
L
A
R
R
T
E
P
I
R
I
E
----------------------------------------------------
35
Fugue
69.97
16%
-52
* C3 *
4C91
2
?
A:
[32-854]
EQFV
I
F
T
P
A
G
N
H
F
P
L
V
A
N
G
V
P
C
P
I
Y
I
D
SSED
K
G
V
--
M
I
A
-
A
G
N
L
-
Q
Q
D
I
L
Q
V
C
G
K
K
P
E
L
-
L
T
S
T
S
S
K
R
C
I
-
I
A
-
G
T
Y
GT
P
------
F
I
K
K
L
M
S
A
G
K
---------
I
D
K
K
E
L
D
G
K
N
E
K
Y
I
L
Q
V
I
A
N
P
C
E
G
I
D
EAV
V
I
I
G
S
D
-------
R
R
G
-
T
I
-
Y
G
I
Y
E
L
S
E
Q
M
GVSPWYWWADVPVMKQA
N
V
Y
I
K
P
G
Q
-----
Y
S
D
G
EPAV
T
Y
R
G
I
F
-
L
N
D
E
A
P
C
L
T
R
W
V
K
H
-----
T
Y
G
T
N
Y
G
D
H
R
F
Y
A
R
V
C
E
L
------
I
L
R
--
L
K
GNFLWPAMWSWAFYADDP
Q
N
S
K
T
A
S
E
M
G
V
I
I
G
T
S
HH
E
P
-------
M
----
A
-----
R
----
N
H
-
Q
E
W
S
R
K
R
K
E
Y
G
A
W
D
YTTN-
Q
K
V
I
D
Q
F
F
R
-
E
--------
G
---
I
E
R
M
Q
G
T
-
E
D
I
V
T
I
G
---------
M
N
V
K
L
-------
L
E
N
V
V
--
K
N
Q
------
R
K
I
---
I
E
E
V
T
K
R
P
A
K
E
T
P
Q
V
W
A
L
Y
K
E
-
V
L
D
Y
--------
Y
D
K
G
M
R
V
P
DDVIM
L
L
--------
C
D
D
N
WGNV
C
---
R
-
L
P
N
------------
A
K
-------
E
R
K
H
P
G
G
W
G
M
Y
----
Y
H
V
D
Y
V
G
A
P
-----
R
-
N
S
K
W
L
--------
N
V
T
---
P
I
Q
N
-----
M
W
E
Q
L
Q
L
T
Y
D
Y
G
V
E
-
K
L
W
--
I
----
L
----------------
N
V
G
D
-----------
L
K
P
M
E
-----
Y
P
I
T
L
F
M
D
M
A
---
W
N
P
K
QF
N
V
S
N
L
L
D
H
P
R
R
F
C
A
Q
Q
FG
E
D
Q
A
D
E
A
M
R
I
L
N
L
Y
S
K
Y
N
G
R
VT
G
E
M
L
D
R
N
T
Y
N
-
L
-----------
E
T
G
E
W
K
Q
V
-
S
D
E
Y
L
K
L
E
A
E
A
L
R
Q
Y
I
S
L
-------------
K
P
E
Y
K
D
A
Y
K
Q
L
I
L
F
P
V
Q
A
M
A
N
L
Y
E
M
Y
Y
A
Q
A
M
N
H
K
L
Y
K
E
N
N
P
Q
A
N
E
W
A
D
K
V
E
Q
A
-
F
A
R
D
K
A
L
S
D
D
Y
---
N
N
I
M
S
G
G
K
W
K
N
M
M
IQKHIGYTSW
N
D
N
F
P
A
DTLP
K
I
Y
R
IENP
E
K
A
V
G
G
Y
V
F
T
G
Q
D
G
Y
I
-
A
--
I
E
-----
A
E
H
Y
Y
S
A
K
A
A
P
D
T
E
W
T
V
I
P
Y
MGRTL
S
G
M
A
L
M
P
Y
T
Q
P
T
DG
A
S
I
S
Y
K
I
-
K
L
P
K
G
I
D
K
V
T
V
H
V
I
V
K
STLAFHDRK
G
H
E
Y
S
I
G
F
E
G
G
K
D
Q
T
I
N
F
N
H
N
L
N
E
L
P
E
N
V
Y
S
I
Y
Y
P
T
V
A
R
R
I
V
E
K
K
A
K
L
N
V
P
NTSDG
M
Q
T
I
T
F
K
P
LDPG
I
V
L
E
K
LVVDYGGYKKSYLFMNE
S
K
S
K
R
E
37
Fugue
66.56
15%
9
- C3 -
4U3E
6
?
A:
[12-670]
-------------------
S
G
-----------
L
V
--
G
S
H
M
K
V
Q
Y
-
S
-
F
E
R
E
F
E
E
----
L
M
S
D
L
L
S
K
Y
G
Y
E
M
F
Q
M
D
G
L
--
G
------
D
Q
L
D
V
V
K
F
T
E
D
F
V
R
R
G
I
I
E
S
T
I
D
A
N
A
N
V
R
V
T
N
I
S
T
Y
F
I
E
I
S
K
P
H
T
----
Y
L
Y
S
----
L
Y
R
I
W
Q
K
M
K
E
M
F
G
K
G
V
A
D
E
---------------------
F
V
E
A
-
Q
I
N
GA
V
Y
L
H
D
----
R
H
H
A
A
L
M
P
Y
C
F
A
Y
T
L
K
P
I
V
E
K
GLPFI
K
T
I
K
S
E
P
-
A
K
H
L
S
T
F
I
Q
H
------
V
I
Q
--
F
V
M
-----------------
F
A
S
N
Q
S
S
G
A
V
G
L
P
-----
D
F
-------
F
----
V
-----------
W
M
W
Y
F
V
K
K
D
L
K
E
G
I
I
P
-----
R
D
K
L
D
W
Y
I
E
Q
H
--------
F
---
Q
I
L
T
Y
S
L
-
N
Q
P
I
R
T
T
---------
Q
-
S
P
Y
-------
T
N
F
T
Y
LD
R
N
Y
------
I
K
A
I
F
E
G
E
R
Y
P
D
G
S
L
I
T
D
H
V
E
D
I
I
A
L
Q
-
K
H
Y
W
--------
E
W
-----------
V
S
--------
R
E
R
E
----
R
---
Q
M
F
T
F
------------
P
V
-------
L
T
A
S
L
L
----
Y
----
K
D
G
K
F
L
D
E
D
-----
S
-
A
R
F
I
N
--------
K
I
N
M--
K
W
Q
D
-----
T
N
W
Y
I
S
D
S
I
D
A
V
A
S
-
C
E
K
--
L
---------------------------
K
G
---
R
M
N
S
I
G
G
S
D
LNIGS
F
K
V
I
T
V
N
L
P
R
---
I
A
L
E
--
S
G
G
D
R
E
K
Y
L
Q
I
L
R
H
R
V
--
Q
L
I
K
K
A
L
A
A
V
R
E
I
I
K
E
R
I
S
E
--
G
L
L
P
L
Y
E
N
G
L
M
L
L
N
RQ
Y
G
T
I
G
V
T
G
V
W
E
S
A
S
I
M
G
L
T
T
E
D
I
D
G
L
K
Y
T
E
E
G
E
V
F
V
--
D
N
V
L
D
T
I
R
E
E
A
E
K
G
Y
H
E
Y
G
-
F
T
F
N
I
E
Q
V
P
A
E
K
A
A
V
T
L
A
Q
K
D
R
F
L
F
G
E
K
Q
P
F
E
I
Y
S
-
N
Q
W
V
P
L
M
A
N
T
D
-----
V
L
---
N
R
I
R
Y
S
G
K
W
D
K
K
V
----------
S
G
G
A
I
L
------------
H
I
N
L
G
E
S
F
K
T
E
E
E
S
F
N
M
V
K
M
I
A
D
M
G
V
M
Y
F
A
F
N
T
K
I
S
V
C
E
D
G
H
A
F
--
Y
------
G
E
R
C
P
V
C
G
K
A
K
-----
V
D
E
Y
M
R
I
V
G
Y
L
V
P
V
S
A
F
N
K
E
R
--------------
R
E
I
E
Y
P
R
R
Q
F
Y
D
---
S
L
T
I
R
-----------------------------------------------------------------------
36
Fugue
59.39
11%
-32
- C1 -
2BIB
12
?
A:
[1-540]
-----
Q
E
S
S
G
N
K
I
H
F
I
----------------
N
V
--
Q
E
G
-
G
S
D
A
-
I
-
I
L
E
S
-----------
N
G
H
F
A
M
V
D
-
T
G
-
E
D
Y
--
D
FPDGSD
S
R
Y
P
W
R
E
G
I
E
T
S
Y
K
H
V
L
T
D
R
V
F
R
R
L
K
E
L
S
V
Q
K
L
D
F
I
L
--------------
V
T
H
T
H
S
D
H
I
G
N
V
D
-
E
L
-
L
S
T
Y
P
V
D
R
---------------------
V
Y
L
K
-
K
-----
Y
S
D
S
----
R
I
T
N
S
E
-
R
L
W
D
N
L
Y
G
Y
D
K
V
L
Q
-----
T
A
T
E
T
G
V
-
S
V
I
Q
N
------------
I
T
--
Q
G
------------------
D
A
H
F
Q
F
G
D
M
D
I
Q
L
-----
Y
N
-------
Y
----------------------
E
N
E
T
D
S
S
G
E
L
-----
K
K
I
W
D
D
N
S
N
S
L
--------
I
---
S
V
V
K
V
N
G
-
K
K
I
Y
L
G
G
DLDNVHGAE
D
-
K
Y
G
-------
P
L
I
G
K
--
V
D
L
------
M
K
F
---
N
H
H
H
D
T
N
K
S
N
T
K
D
F
I
K
N
L
S
P
S
-
L
I
V
Q
--------
T
S
-----------
D
S
--------
L
P
W
K
--------
N
-
G
V
D
------------
S
E
-------
Y
V
N
W
L
K
----
E
----
R
G
I
E
R
I
N
A
A
-----
S
-
K
D
Y
D
A
--------
T
V
F
---
D
I
R
K
-----
D
G
F
V
N
I
S
T
S
Y
K
P
I
P
-
S
F
Q
--
A
----
G
----------------
W
H
K
S
A
Y
G
N
---
W
-
W
Y
Q
A
P
D
S
-----
T
G
E
Y
A
V
G
W
N
E
---
I
E
-----------------------------------------
G
--
E
W
Y
Y
F
N
Q
T
G
I
-
L
L
Q
--
N
Q
W
K
K
W
N
N
H
W
F
Y
L
T
D
-
S
-------
G
A
S
A
K
N
W
K
K
I
D
G
--
I
W
Y
Y
F
N
K
E
N
Q
M
E
I
G
W
V
Q
D
---------------
K
E
Q
W
Y
Y
L
D
V
D
G
S
M
K
T
G
W
L
Q
Y
M
G
-
Q
W
Y
Y
F
A
-
P
S
G
E
M
K
M
G
W
V
K
D
KE
T
W
Y
Y
M
D
S
T
-
G
V
M
K
----------
T
G
E
I
E
V
--------------
A
G
Q
H
Y
Y
L
E
D
S
G
A
M
K
---------------
Q
G
W
H
K
K
A
N
D
W
Y
F
Y
K
T
D
------
G
S
R
A
V
G
W
I
K
D
K
-----
D
K
W
Y
-
F
L
K
E
N
G
Q
L
L
V
N
G
K
T
P
E
--------------
G
Y
T
V
D
S
S
------
G
A
W
L
V
D
V
S
I
E
K
-------------------------------------------------------------------
30
Fugue
57.12
14%
-44
- C1 -
2QJC
3
?
A:
[8-249]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
A
N
-
V
V
T
L
P
N
V
T
G
R
------
V
I
I
--
V
G
------------------
D
I
H
G
C
R
A
Q
L
E
D
L
L
-----
R
A
-------
V
----
S
-----
F
KQGS
D
T
-
L
V
A
V
G
D
L
V
N
K
G
P
D
S
-----
F
G
V
V
R
L
L
K
R
L
---------
G
---
A
Y
S
V
L
G
N
-
H
D
A
K
L
L
K
---------
L
-
V
K
K
-------
L
S
L
A
P
--
L
A
Q
------
S
I
P
---
T
D
V
E
T
Y
L
S
Q
L
P
H
I
I
R
I
P
A
H
N
V
M
V
A
H
A
GLHPQRPV
D
R
-----------
Q
Y
--------
E
D
E
V
----
T
TMR
N
-
L
I
E
------------
K
V
-------
T
L
T
A
T
E
----
E
----
T
N
D
G
G
K
P
W
A
-----
S
M
W
R
G
P
E
--------
T
V
V
F
G
H
D
A
R
R
-----
G
L
Q
E
Q
Y
K
P
L
A
I
G
L
D
-
S
R
C
--
V
YG
G
R
L
----------------
S
A
A
V
F
P
G
G
---
C
-
I
I
S
V
P
G
W
-----
N
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
56.21
11%
-38
- C1 -
2DFJ
2
APAH_SHIFL
A:
[2-268]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
------
T
Y
L
--
I
G
------------------
D
V
H
G
C
Y
D
E
L
I
A
L
L
-----
H
K
-------
V
EFTP
G
-----
K
----
D
T
-
L
W
L
T
G
D
L
V
A
R
G
P
G
S
-----
L
D
V
L
R
Y
V
K
S
L
G
--------
D
S--
V
R
L
V
L
G
N
-
H
D
L
H
L
L
A
---------
V
-
F
A
G
-------
I
S
---------------
R
N
---
K
P
K
D
R
L
T
P
L
L
E
A
P
D
A
D
E
L
L
N
W
-
L
R
R
Q
--------
P
L
-----------
L
Q
--------
I
D
E
E
----
K
---
K
-
L
V
M
------------
A
H
AGITPQW
D
L
Q
T
A
K
----
E
----
C
A
R
D
V
E
A
V
L
-----
S
-
S
D
S
Y
P
--------
F
F
L
---
D
A
M
Y
-----
G
D
M
P
N
N
W
S
P
E
L
R
G
L
-
G
R
L
--
R
----
F
----------------
I
T
N
A
F
T
R
M
---
R
-
F
C
F
P
N
G
Q
-----
L
D
M
Y
S
K
E
S
P
E
---
E
A
P
A
--
P
L
K
P
W
F
A
I
P
G
P
V
A
E
E
Y
--
S
I
A
F
G
H
W
A
S
L
E
G
K
-----
G
T
--
P
E
G
I
Y
A
L
D
T
G
-
C
C
W
--
G
G
S
L
T
C
L
R
W
E
D
K
Q
Y
F
-
V
Q
P
S
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
Fugue
55.58
14%
-32
- C1 -
3QFM
2
?
A:
[11-268]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
T
K
------
I
A
L
--
L
S
------------------
D
I
H
G
N
T
T
A
L
E
A
V
L
-----
A
D
-------
A
----
R
Q
L
G--
V
----
D
E
-
Y
W
L
L
G
D
I
L
M
P
G
T
G
R
-----
R
R
I
L
D
L
L
D
Q
L
P
--------
I
---
T
A
R
V
L
G
N
-
W
E
D
S
L
W
H
---------
G
-
V
R
K
ELDSTR
P
S
Q
R
Y
L
--
L
R
Q
------
C
Q
Y
---
V
L
E
E
I
S
L
E
E
I
E
V
L
H
N
Q
P
L
Q
I
H
-
R
Q
F
G
--------
D
L
-----------
T
V
G
I
S
HHLPD
K
N
W
G
----
R
---
E
-
L
I
H
------------
T
G
-------
K
Q
E
E
F
D
----
R
L
V
T
H
P
P
C
D
I
A
V
Y
G
-----
H
-
I
H
Q
Q
L
L
R
Y
G
TGG
Q
L
I
V
---
N
P
G
S
-----
I
G
Q
P
F
F
L
D
A
Q
L
R
K
D
-
L
R
A
--
Q
----
Y
----------------
M
I
L
E
F
D
D
K
GLV
D
-
M
D
F
R
R
V
D
-----
Y
D
V
A
A
E
L
Q
L
A
---
K
D
L
R
--
L
P
Y
F
E
V
Y
Y
E
S
L
V
N
G
I
H
--
H
T
H
H
Q
E
F
L
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
54.62
17%
-26
- C1 -
1G5B
4
PP_LAMBD
A:
[1-219]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
R
Y
Y
E
K
I
D
G
S
KYR
N
I
W
V
V
G
DL
H
G
------------------
C
Y
T
N
L
M
N
K
L
D
T
I
G
-----
F
D
-------
N
----
K
-----
K
----
D
L
-
L
I
S
V
G
D
L
V
D
R
G
A
E
N
-----
V
E
C
L
E
L
I
T
F
-
P
--------
W
---
F
R
A
V
R
G
N
-
H
E
Q
M
M
I
D
---------
G
-
L
S
E
RGNV---
N
H
W
L
L
--
N
G
G
------
G
W
F
---
F
N
L
D
Y
D
K
E
I
L
A
K
A
L
A
H
K
A
D
E
L
-
P
L
I
I
--------
E
L
-----------
V
S
--------
K
D
K
K
----
Y
---
V
-
I
C
H
ADYPFD
E
Y
E
F
GK
P
V
-------
D
H
Q
Q
V
I
----
W
----
N
R
E
R
I
S
N
S
Q
N
GI
V
K
E
-
I
K
G
A
D
--------
T
F
I
F
G
H
T
P
A
V
-----
K
P
L
K
F
A
N
Q
M
Y
I
D
T
G
-
A
V
F
CG
N
----
L
----------------
T
L
I
Q
V
Q
G
A
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
Fugue
51.02
9%
-27
* C1 *
1NNW
3
?
A:
[2-252]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
Y
V
A
V
------
L
A
N
--
I
A
------------------
G
N
L
P
A
L
T
A
A
L
S
R
I
-----
E
E
-------
M
----
R
E
E
G
Y
E
I
----
E
K
-
Y
Y
I
L
G
N
I
V
G
L
F
P
Y
P
-----
K
E
V
I
E
V
I
K
D
L
T
--------
K
K
EN
V
K
I
I
R
G
K
-
Y
D
Q
I
I
A
M
---------
S
-
D
P
H
-------
A
T
D
P
G
--
Y
I
D
K
LELP
G
H
V
K
---
K
A
L
K
F
T
W
E
K
L
G
H
E
G
R
E
Y
L
R
D
L
-
P
I
Y
L
--------
V
D
-----------
K
I
--------
G
G
N
E
----
V
---
F
-
G
V
Y
GSP---------
I
N
-------
P
F
D
G
E
V
----
L
----
A
E
Q
P
T
S
Y
Y
E
-----
A
-
I
M
R
P
V
--------
K
D
Y
---
E
M
L
I
-----
V
A
S
P
M
Y
P
V
D
A
M
T
R
Y
-
G
R
V
--
V
----
C
PGSVGFPPGKEHKA
T
F
A
L
V
D
V
D
T
L
---
K
-
P
K
F
I
E
V
E
-----
Y
D
K
K
I
I
E
E
R
I
---
R
A
E
G
--
L
P
E
E
I
I
K
I
L
Y
H
G
G
R
P
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
50.27
20%
8
- C2 -
1QWZ
3
?
A:
[21-218]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
-
E
D
K
Q
E
R
A
N
Y
E
K
L
Q
Q
K
F
Q
M
L
M
S
K
H
Q
A
H
V
R
P
Q
F
E
S
L
E
K
I
N
K
D
I
V
G
W
I
K
L
S
G
T
S
L
N
Y
P
V
L
Q
G
K
T
N
H
D
Y
L
N
L
D
F
E
R
E
H
R
R
K
-
G
S
I
F
M
D
-
F
R
N
E
L
--
K
N
L
N
---
H
N
T
I
L
---
Y
G
H
H
V
----------
G
D
N
T
M
F
------------
D
----------------
V
--
L
E
D
-
Y
L
-
K
Q
S
F
Y
E
K
H
K
I
I
E
F
D
N
K
Y
G
K
Y
------
Q
L
Q
V
F
S
A
Y
K
T
T
-----
T
K
D
N
-
Y
I
R
T
D
F
E
N
D
Q
D
Y
Q
Q
F
L
--------------
D
E
T
K
R
K
S
V
I
N
S
D
V
N
V
T
V
K
D
R
I
M
T
L
S
T
C
E
D
A
Y
------------------------------------------------------------
7
PsiBlast_PDB
49.67
20%
13
- C2 -
1QXA
2
?
A:
[22-218]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
D
K
Q
E
R
A
N
Y
E
K
L
Q
Q
K
F
Q
M
L
M
S
K
H
Q
A
H
V
R
P
Q
F
E
S
L
E
K
I
N
K
D
I
V
G
W
I
K
L
S
G
T
S
L
N
Y
P
V
L
Q
G
K
T
N
H
D
Y
L
N
L
D
F
E
R
E
H
R
R
K
-
G
S
I
F
M
D
-
F
R
N
E
L
--
K
N
L
N
---
H
N
T
I
L
---
Y
G
H
H
V
----------
G
D
N
T
M
F
------------
D
----------------
V
--
L
E
D
-
Y
L
-
K
Q
S
F
Y
E
K
H
K
I
I
E
F
D
N
K
Y
G
K
Y
------
Q
L
Q
V
F
S
A
Y
K
T
T
-----
T
K
D
N
-
Y
I
R
T
D
F
E
N
D
Q
D
Y
Q
Q
F
L
--------------
D
E
T
K
R
K
S
V
I
N
S
D
V
N
V
T
V
K
D
R
I
M
T
L
S
T
C
E
D
A
Y
------------------------------------------------------------
8
PsiBlast_PDB
49.06
20%
10
- C2 -
1NG5
-
?
A:
[5-198]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
E
R
A
N
Y
E
K
L
Q
Q
K
F
Q
M
L
M
S
K
H
Q
A
H
V
R
P
Q
F
E
S
L
E
K
I
N
K
D
I
V
G
W
I
K
L
S
G
T
S
L
N
Y
P
V
L
Q
G
K
T
N
H
D
Y
L
N
L
D
F
E
R
E
H
R
R
K
-
G
S
I
F
M
D
-
F
R
N
E
L
--
K
N
L
N
---
H
N
T
I
L
---
Y
G
H
H
V
----------
G
D
N
T
M
F
------------
D
----------------
V
--
L
E
D
-
Y
L
-
K
Q
S
F
Y
E
K
H
K
I
I
E
F
D
N
K
Y
G
K
Y
------
Q
L
Q
V
F
S
A
Y
K
T
T
-----
T
K
D
N
-
Y
I
R
T
D
F
E
N
D
Q
D
Y
Q
Q
F
L
--------------
D
E
T
K
R
K
S
V
I
N
S
D
V
N
V
T
V
K
D
K
I
M
T
L
S
T
C
E
D
A
Y
------------------------------------------------------------
17
HHSearch
43.66
19%
34
- C2 -
1AUI
2
PP2BA_HUMAN
A:
[93-249]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
------------------
Q
F
F
D
L
M
K
L
F
E
V
G
G
-----
S
P
------------
A
-----
N
----
T
R
-
Y
L
F
L
G
D
Y
V
D
R
G
Y
F
S
-----
I
E
C
V
L
Y
L
W
A
L
K
I
L
Y
P
K---
T
---
L
F
L
L
R
G
N
-
H
E
C
R
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
HHSearch
42.99
17%
-8
- C2 -
1NNW
1
?
A:
[12-81]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
------------------
N
L
P
A
L
T
A
A
L
S
R
I
E
-----
E
M
R
E
E
G
---
Y
----
E
-----
I
----
E
K
-
Y
Y
I
L
G
N
I
V
G
L
F
P
Y
P
-----
K
E
V
I
E
V
I
K
D
L
T
K
K
E-----
N
---
V
K
I
I
R
G
K
-
Y
D
Q
I
I
A
M
---------
S
-
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
HHSearch
42.51
18%
44
- C2 -
1FJM
3
PP1A_RABIT
A:
[67-133]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
------------------
Q
Y
Y
D
L
L
R
L
F
E
Y
G
G
-----
F
P
------------
P
-----
E
----
S
N
-
Y
L
F
L
G
D
Y
V
D
R
G
K
Q
S
-----
L
E
T
I
C
L
L
L
A
Y
K
I
K
Y
P
E---
N
---
F
F
L
L
R
G
N
-
H
E
C
A
S
I
N
---------
R
-
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
42.42
26%
21
- C2 -
2DFJ
2
APAH_SHIFL
A:
[11-76]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
------------------
C
Y
D
E
L
I
A
L
L
H
K
V
E
-----
F
T
-------
P
----
G
-----
K
----
D
T
-
L
W
L
T
G
D
L
V
A
R
G
P
G
S
-----
L
D
V
L
R
Y
V
K
S
L
G
D-------
S
---
V
R
L
V
L
G
N
-
H
D
L
H
L
L
A
---------
V
-
F
A
G
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
40.39
19%
27
- C2 -
2Z72
2
?
A:
[81-158]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
------------------
Q
Y
D
V
L
L
T
L
L
K
K
Q
K
-----
I
I
DSDGNWA
F
----
G
-----
E
----
G
H
-
M
V
M
T
G
D
I
F
D
R
G
H
Q
V
-----
N
E
V
L
W
F
M
Y
Q
L
D
Q
Q
A
R
D
A
G
G
M
---
V
H
L
L
M
G
N
-
H
E
Q
M
V
L
G
---------
G
-
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
HHSearch
39.63
20%
46
- C2 -
3H63
3
PPP5_HUMAN
A:
[71-136]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
F
Y
D
L
L
N
I
F
E
L
N
G
-----
L
P
-------
S
----
E
-----
T
----
N
P
-
Y
I
F
N
G
D
F
V
D
R
G
S
F
S
-----
V
E
V
I
L
T
L
F
G
F
K
L
L
Y
P
D---
H
---
F
H
L
L
R
G
N
-
H
E
T
D
N
M
N
---------
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
HHSearch
37.99
25%
27
- C2 -
3IB7
5
CPDA_MYCTU
A:
[51-114]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
R
L
G
E
L
L
E
Q
L
N
-----
Q
S
G------
L
----
R
-----
P
----
D
A
-
I
V
F
T
G
D
L
A
D
K
G
E
P
A
A
Y
R
K
L
R
G
L
V
E
P
F
A
A
Q
L
G
A
------
E
---
L
V
W
V
M
G
N
-
H
D
D
R
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
HHSearch
37.55
25%
45
- C2 -
3RQZ
2
?
A:
[18-74]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
E
A
V
L
S
D
A
G
-------------------
R
-----
V
----
D
D
-
I
W
S
L
G
D
I
V
G
Y
G
P
R
P
-----
R
E
C
V
E
L
V
R
V
L
A
--------
P
---
N
I
S
V
I
G
N
-
H
D
W
A
C
I
G
---------
R
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------