@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0835: (2016-03-19 )
VSKNVKKIVITLFALIMTVGLASGFIAPIKASADTNNFTVKVEYVDADGAEIAPSDILTDYHYVSTPKDIPGYKLREIPHNATGNITDTGIIVRYIYDKTIDVRYVDETGKDLLPVVEIINSEAAVLETISDYTFVKKDISIDGLHIIFRYKKNISTIPDFGKPNQVTVNYLDENKTPIAPSLYLSGLFNEAYNVPMKKIKGYTLLKYDSEILGVFTESPQTINIIYQKKAPEQAPSMEPLPDPTVPESPQVEKSKIKKSKIETTEKRTTSKVKIAPKALKLTKVEQKKQETKDSLPKTGDSSVNLLITCLGIIAISCGVYLLVQQSQKRRRKE
Atome Classification :
(20 SA)
-------.........10...--.....20........30.......----.40..----......50........---60.--...----.------------------.------..70...-------......80.----...-----.....---90........-100-........--110.......120........130-----.......140.---......150........160-----.......170--.....--....180..-------------....--.----------190---..--.-.-.------.---...200-.......210..------.-.-.------.---.220...-..-----------..230...---....-240......-----------.250.......260.......270....-..-----------.280--------........290.......300.......310....-...320--........330..------------------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
-------VSK
N
V
K
K
I
V
I
T
L
F
A
--
L
I
M
T
V
G
LASGFIA
P
I
KASADTN
N
F
----
T
V
K
V
E
----
Y
VDADGAEIA
P
S
D
I
LT---DYH--YVS----T------------------P------KDI-PGY-------
K
L
REIPH-N----ATG-----NITD
T
---
G
I
I
V
R
Y
I
YDK-
T
I
--
D
V
R
Y
VDET--GK
D
L
L
P
V
V
E
I
IN-S
E
A
A
V
L
E
T
ISD-----
Y
T
F
V
KKDISID---
G
L
H
I
I
F
R
-YKKNISTIPDFG-----KP
N
Q
V
T
V
N
----
Y
LDEN--KTPI
A
P
S
L
Y
-------------
L
S
G
L
--
F
----------
N
-----
E
A--Y-N-V------
P
---
M
K
KIK
G
-
Y
T
L
L
KYD
S
E
I
L
G
------
V
-F-T------E---SP
Q
T
I
N
I
-
I
Y
-----------QKKAPEQA---PSME-PLPDPTVPE-----------SPQ
V
E
K
S
K
I
K
K
SKIETTEKRTT
S
K
V
K
IA-P
K
-----------
A
L
K
---------
L
T
K
V
E
Q
K
K
Q
E
T
K
DSLPKTGDS
S
V
N
L
L
I
T
C
L
G
I
I
A
I
-SCGV
Y
---
L
L
V
Q
Q
S
Q
K
R
RRKE------------------------------------------
29
Fugue
81.68
90%
-63
- C8 -
2KT7
-
?
A:
[34-135]
-----------------------------------------
M
D
T
N
N
F
----
T
V
K
V
E
----
Y
V
D
A
D
G
A
E
I
A
P
S
D
T
L
T
---
D
Y
H
--
Y
V
S
----
T
------------------
P
------
K
D
I
-
P
G
Y
-------
K
L
R
E
I
P
H
-
N
----
A
T
G
-----
N
I
T
D
T
---
G
I
I
V
R
Y
I
Y
D
K
-
I
I
--
D
V
S
Y
V
D
E
T
--
G
K
D
L
L
P
V
V
E
I
I
N
-
S
E
A
A
V
L
E
H
H
H
H
-----
H
H
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
81.20
96%
-64
- C8 -
2KT7
-
?
A:
[35-129]
------------------------------------------
D
T
N
N
F
----
T
V
K
V
E
----
Y
V
D
A
D
G
A
E
I
A
P
S
D
T
L
T
---
D
Y
H
--
Y
V
S
----
T
------------------
P
------
K
D
I
-
P
G
Y
-------
K
L
R
E
I
P
H
-
N
----
A
T
G
-----
N
I
T
D
T
---
G
I
I
V
R
Y
I
Y
D
K
-
I
I
--
D
V
S
Y
V
D
E
T
--
G
K
D
L
L
P
V
V
E
I
I
N
-
S
E
A
A
V
L
E
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
37
Fugue
77.88
20%
-9
* C7 *
4CI0
4
?
A:
[2-386]
-----------
S
E
R
I
V
I
S
------------------------
P
T
S
R
Q
----
E
G
H
A
E
----
L
V
----
M
E
V
D
D
E
G
I
V
T
---
K
G
R
--
Y
F
S
----
I
------------------
T
PVRG
L
E
K
M
V
-
T
G
K
-------
A
P
E
T
A
P
V
-
M
----
V
Q
R
ICGVC
P
I
P
H
T
---
L
A
S
V
E
A
I
D
D
S
L
D
I
--
E
V
P
K
A
G
R
L
--
L
R
E
L
T
L
A
A
H
H
V
N
-
S
H
A
I
H
H
F
L
I
A
P
------
D
F
V
P
E
N
L
M
A
D
---
A
I
N
S
V
S
E
-
I
R
K
N
A
Q
Y
V
V
D
M
V
A
GEGI
H
P
S
D
V
R
I
G
----
G
M
A
D
N
--
I
T
E
L
A
R
K
R
L
-------------
Y
A
R
L
K
Q
L
----------
K
-----
P
K
--
V
-
N
-
E
------
H
---
V
E
L
M
I
G
-
L
I
E
D
K
G
L
P
E
G
L
G
------
V
-
H
-
N
------
Q
---
P
T
L
A
S
H
Q
-
I
Y
GDRTKFDLDR
F
T
E
I
M
P
E
S
W
YDD
P
E
I
A
-
K
R
A
C
S
T
I
P
L
Y
DG
R
N
V
E
V
G
P
R
A
R
M
V
E
F
Q
G
F
K
E
R
G
V
V
A
Q
H
V
A
R
A
L
E
M
K
T
A
L
S
R
-----------
A
I
E
---------
I
L
D
E
L
D
T
S
A
P
V
R
A
D
F
D
E
R
G
T
G
K
-----
L
G
I
G
A
I
E
A
-
P
R
G
L
D
---
V
H
M
A
K
V
E
N
G
K
I
Q
F
Y
S
A
L
V
P
T
T
W
N
I
P
T
M
G
P
A
T
EGFHHEY
G
P
H
V
I
R
A
Y
DPCLSCATH
5
HHSearch
77.22
96%
-62
- C8 -
2KT7
-
?
A:
[38-122]
---------------------------------------------
N
F
----
T
V
K
V
E
----
Y
V
D
A
D
G
A
E
I
A
P
S
D
T
L
T
---
D
Y
H
--
Y
V
S
----
T
------------------
P
------
K
D
I
-
P
G
Y
-------
K
L
R
E
I
P
H
-
N
----
A
T
G
-----
N
I
T
D
T
---
G
I
I
V
R
Y
I
Y
D
K
-
I
I
--
D
V
S
Y
V
D
E
T
--
G
K
D
L
L
P
V
V
E
I
I
N
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
Fugue
76.66
16%
-9
- C7 -
1F52
2
GLNA_SALTY
A:
[101-468]
--------
D
R
D
P
R
S
I
A
K
R
A
E
D
--
Y
L
R
A
T
G
I
A
-----------
D
T
V
L
F
----
G
P
E
P
E
----
F
F
L
F
D
D
I
R
F
G
A
S
I
S
G
S
---
H
V
A
--
I
D
D
----
I
EGAWNSSTKYEGGNKGHR
P
------
G
V
K
-
G
G
Y
FPVPPVD
S
A
Q
D
I
R
S
-
E
----
M
C
L
-----
V
M
E
Q
M
---
G
L
V
V
E
A
H
H
H
E
-
V
A
TA
G
Q
N
E
V
A
T
R
--
F
N
T
M
T
K
K
A
D
E
I
Q
-
I
Y
K
Y
V
V
H
N
V
A
H
R
F
G
K
T
A
T
F
M
P
K
P
M
F
G
D
N
G
S
G
M
H
C
H
M
S
L
A
K
N
G
T
N
L
F
S
G
D
------
K
Y
A
G
L
S
E
Q
----
A
L
Y
Y
I
--
G
G
V
I
K
H
A
K
A
-------------
I
N
A
L
--
A
----------
N
-----
P
T
--
T
-
N
-
S
------
Y
---
K
R
L
V
P
G
-
Y
-----
E
A
P
V
M
L
------
A
-
Y
-
S
------
A
---
R
N
R
S
A
S
I
R
I
P
-----------
V
V
A
-
S
P
K
A
---
R
R
I
E
V
R
F
P
D
P
A
A
-------------
N
P
Y
L
C
F
A
A
L
L
M
A
G
L
D
G
I
K
N
K
I
H
P
G
E
P
M
D
-
K
N
-----------
L
Y
D
---------
L
P
P
E
E
A
K
E
---
I
P
Q
V
A
G
S
L
E
E
A
L
N
A
L
D
L
D
R
E
F
L
K
A
-
G
-
G
V
F
T
D
E
A
I
D
A
Y
I
A
L
R
R
E
-
E
D
D
R
V
R
M
TPH
P
V
E
F
E
L
YYSV-----------------------
30
Fugue
76.65
87%
-65
- C8 -
2KVZ
-
?
A:
[1-85]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
D
F
G
-----
K
P
N
Q
V
T
V
N
----
Y
L
D
E
N
--
N
T
S
I
A
P
S
L
Y
-------------
L
S
G
L
--
F
----------
N
-----
E
A
--
Y
-
N
-
V
------
P
---
M
K
K
I
K
G
-
Y
T
L
L
K
Y
D
S
E
I
L
G
------
V
-
F
-
T
------
E
---
S
P
Q
T
I
N
I
-
I
Y
-----------
Q
K
K
A
P
E
Q
A
---
L
E
H
H
-
H
H
H
H
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
75.96
97%
-75
- C8 -
2KVZ
-
?
A:
[2-77]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
F
G
-----
K
P
N
Q
V
T
V
N
----
Y
L
D
E
N
--
N
T
S
I
A
P
S
L
Y
-------------
L
S
G
L
--
F
----------
N
-----
E
A
--
Y
-
N
-
V
------
P
---
M
K
K
I
K
G
-
Y
T
L
L
K
Y
D
S
E
I
L
G
------
V
-
F
-
T
------
E
---
S
P
Q
T
I
N
I
-
I
Y
-----------
Q
K
K
A
P
E
Q
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
HHSearch
73.68
97%
-76
- C8 -
2KVZ
-
?
A:
[6-77]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
N
Q
V
T
V
N
----
Y
L
D
E
N
--
N
T
S
I
A
P
S
L
Y
-------------
L
S
G
L
--
F
----------
N
-----
E
A
--
Y
-
N
-
V
------
P
---
M
K
K
I
K
G
-
Y
T
L
L
K
Y
D
S
E
I
L
G
------
V
-
F
-
T
------
E
---
S
P
Q
T
I
N
I
-
I
Y
-----------
Q
K
K
A
P
E
Q
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
32
Fugue
63.01
18%
-9
- C9 -
4IIK
18
SIDD_LEGPH
A:
[1-314]
------------
M
R
S
I
I
T
Q
I
C
NG
V
L
H
G
Q
S
Y
Q
S
G
-----
S
N
D
L
D
K
G
N
S
----
E
I
F
A
S
S
L
F
V
H
L
N
E
Q
G
K
E
I
K
D
S
D
------
D
K
I
--
V
I
G
----
Y
------------------
T
------
K
D
---------------------------
G
-----
M
A
F
Q
I
---
V
V
D
G
F
Y
G
C
E
R
-
Q
A
--
V
F
S
F
I
D
N
Y
--------
V
L
P
L
I
D
-
N
F
S
L
D
L
T
R
Y
P
D
---------
S
K
K
V
T
E
S
---
L
I
H
T
I
Y
S
-
L
R
S
K
H
A
P
L
A
E
F
-------
T
M
S
L
C
V
T
----
Y
Q
K
D
E
--------
Q
L
F
-------------
C
A
G
F
--
G
----------
I
-----
G
D
--
T
-
G
-
I
------
A
---
I
K
R
N
E
G
T
I
E
Q
L
V
C
H
T
E
V
D
G
FKD---
A
-
F
-
D
------
N
---
Y
S
S
A
N
I
D
-
L
V
-----------
I
E
R
N
S
V
F
N
---
T
K
V
M
-
P
-
G
D
E
L
V
G
Y
-----------
T
Y
V
P
P
M
L
E
M
T
E
K
E
F
E
V
-
E
K
R
I
V
R
H
L
N
L
D
-
P
G
-----------
N
F
D
DKDP
L
F
S
Q
L
L
Q
V
V
K
S
K
Q
K
Q
L
V
E
Q
A
K
E
T
G
Q
I
Q
R
F
G
D
D
F
T
V
G
R
L
V
I
-
P
D
--
Q
---
L
L
I
N
Q
L
R
I
H
A
L
S
-------------------------------------------
7
HHSearch
62.48
31%
-34
- C8 -
2KVZ
-
?
A:
[6-72]
---------------------------------------------
P
N
----
Q
V
T
V
N
----
Y
L
D
E
N
N
T
S
I
A
P
S
L
Y
L
S
GLF
N
E
A
--
Y
N
V
----
P
------------------
M
------
K
K
I
-
K
G
Y
-------
T
L
L
K
Y
D
S
-
E
----
I
L
G
-----
V
F
T
E
S
---
P
Q
T
I
N
I
I
Y
Q
K
-
K
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
8
HHSearch
62.31
31%
-38
- C8 -
2KT7
-
?
A:
[38-101]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
N
F
T
V
K
V
E
----
Y
V
D
A
D
--
G
A
E
I
A
P
S
D
T
-------------
L
T
---------------
D
-----
Y
H
--
Y
-
V
-
S
------
T
---
P
K
D
I
P
G
-
Y
K
L
R
E
I
P
H
N
A
T
G
------
N
-
I
-
T
------
D
---
T
G
I
I
V
R
Y
-
I
Y
-----------
D
K
I
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
Fugue
60.88
15%
-23
- C9 -
4XNV
15
P2RY1_HUMAN (first)
A:
[38-382]
SFKCA
L
T
K
T
G
F
Q
F
Y
Y
L
P
A
V
Y
I
--
L
V
F
I
I
G
F
L
G
N
S
V
A
I
W
M
F
V
F
H
M
K
P
W
S
G
I
S
V
Y
M
F
N
----
L
A
L
A
D
F
L
Y
V
L
T
L
P
A
L
I
---
F
Y
Y
--
F
N
K
----
T
------------------
D
WIF---
G
D
A
-
M
C
K
-------
L
Q
R
F
I
F
H
V
N
----
L
Y
G
-----
S
I
L
F
L
---
T
C
I
S
A
H
R
Y
S
G
-
V
V
--
Y
P
K
S
L
-------------
G
R
L
K
-
K
K
N
A
I
C
I
S
V
L
V
-----
W
L
I
V
V
V
A
I
S
P
-------
I
L
F
Y
-
S
G
T
G
V
R
-----------
K
N
K
T
I
T
C
Y
----
D
T
T
S
D
--
E
Y
L
R
S
Y
F
I
Y
-------------
S
M
C
T
--
T
----------
V
-----
A
M
--
F
-
C
-
V
------
P
---
L
V
L
I
L
G
-
C
Y
G
L
I
V
R
A
L
I
Y
K
------
M
-
K
-
K
------
Y
---
T
C
T
V
C
G
Y
-
I
Y
-----------
N
P
E
D
G
D
P
D
---
N
G
V
N
-
P
G
T
D
F
K
D
I
V
-----------
C
P
L
C
G
V
G
K
D
Q
F
E
E
V
E
E
P
L
R
R
K
S
I
Y
L
V
I
I
-
V
L
T
V
F
A
V
S
Y
I
P
F
H
V
M
K
---------
T
M
N
L
R
A
R
L
D
F
Q
T
P
A
M
C
A
F
N
D
R
V
Y
A
T
Y
Q
V
T
R
G
L
A
S
L
N
S
C
V
N
P
---
I
L
Y
F
L
A
G
D
T
F
R
R
R
------------------------------------------
4
PsiBlast_PDB
59.19
24%
-46
- C9 -
4FAJ
3
?
A:
[132-264]
---------------------------------------------------------------
S
D
G
T
Q
I
T
A
S
D
F
V
A
---
A
W
Q
--
R
V
V
----
D
------------------
P
------
K
T
V
S
P
N
V
-------
E
L
F
S
A
I
K
-
N
A
K
E
I
A
S
G
-----
K
Q
A
K
D
---
T
L
A
V
K
S
I
G
E
K
-
T
L
--
E
I
E
L
V
E
P
T
PY
F
T
D
L
L
S
L
T
A
Y
Y
P
V
Q
Q
K
A
I
K
E
Y
G
K
D
-----
Y
G
V
S
Q
K
A
I
V
T
N
---
G
A
F
--------
N
L
T
N
L
E
G
V
G
-----
T
S
D
K
W
T
I
S
KNKE
Y
W
D
Q
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
20
HHSearch
51.92
22%
-68
- C8 -
2KYW
-
?
A:
[4-67]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
A
T
I
T
----
Y
V
D
D
D
KG
G
A
Q
V
G
D
I
V
T
-------------
V
T
G
K
--
T
----------
D
-----
D
S
T
T
Y
-
T
-
V
------
T
---
I
--
P
D
G
-
Y
E
Y
V
G
T
D
G
---
G
------
V
-
V
-
S
------
S
---
D
G
K
T
V
T
I
-
T
F
-----------
A
A
D
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
HHSearch
51.05
21%
-17
- C8 -
3I57
1
?
A:
[2-75]
----------------------------------------------
Q
----
K
V
H
V
Q
----
Y
I
D
G
E
T
D
Q
M
L
R
Q
D
D
L
D
G
Y
T
D
E
T
IP
Y
S
T
A
E
G
I
K
------------------
K
------
F
E
G
-
D
G
Y
-------
E
L
F
K
D
N
F
-
P
----
A
G
E
-----
K
F
D
N
D
DT
N
D
Q
F
Y
T
V
I
F
K
H
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
HHSearch
50.59
21%
-13
- C8 -
3I57
1
?
A:
[2-78]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
K
V
H
V
Q
----
Y
I
D
G
E
--
T
D
Q
M
L
R
Q
D
D
-------------
L
D
G
Y
--
T
----------
D
-----
E
T
--
I
-
P
-
Y
ST
A
E
G
I
K
---
K
F
E
G
D
G
-
Y
E
L
F
K
D
N
F
P
A
G
E
------
K
-
F
-
D
------
N
DDT
N
D
Q
F
Y
T
V
-
I
F
-----------
K
H
H
R
E
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
HHSearch
50.59
13%
-1
- C8 -
3LYY
-
?
A:
[4-102]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
S
T
E
T
I
H
----
Y
V
N
E
D
--
G
D
Q
V
F
E
D
G
G
G
K
L
D
F
T
R
T
V
T
I
D
D
V
T
N
E
--
V
VEYGEWTPVT
D
-----
D
E
--
F
-
A
A
V
------
T
---
S
P
D
K
D
G
-
Y
T
P
D
T
S
E
V
A
A
Q
K
P
D
M
T
D
G
P
D
G
-
T
------
V
---
K
D
V
E
V
T
V
-
T
Y
-----------
T
A
N
P
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
HHSearch
47.26
18%
-25
- C8 -
2LFI
-
?
A:
[9-108]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
V
V
T
Q
T
I
H
----
Y
R
Y
E
D
--
G
A
V
A
H
D
D
H
V
V
S
L
I
F
T
Q
S
G
K
R
D
L
T
N
G
K
--
E
I
W
D-------
S
K
W
S
L
T
Q
T
--
F
E
A
-
L
------
P
---
S
P
V
I
I
G
-
Y
T
A
D
K
P
M
V
G
P
D
E
------
V
-
T
V
D
SKNFLD
K
---
Q
N
R
E
E
T
V
-
I
Y
-----------
S
A
N
T
I
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
41.49
30%
-1
- C9 -
4H0N
2
?
A:
[88-145]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Y
L
D
D
N
--
D
P
R
T
N
S
F
L
Y
-------------
L
I
G
I
--
L
----------
D
-----
Q
L
--
D
-
N
-
V
------
D
Y
I
L
M
E
N
V
K
G
-
F
E
----
N
S
T
V
R
N
------
L
-
F
-
I
------
D
---
K
L
K
E
C
N
F
-
I
Y
-----------
Q
E
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
33
Fugue
41.30
14%
158
- C9 -
1L2P
-
ATPF_ECOLI
A:
[62-122]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
D
-
Q
L
K
K
A
K
A
E
A
-----------
Q
V
I
I
E
Q
A
N
K
R
R
S
Q
I
L
D
E
A
K
A
E
A
E
Q
E
R
T
K
-
I
V
-----------
A
Q
A
---------
Q
A
E
I
E
A
E
R
K
R
A
R
E
E
L
R
K
----------------------------------------------------------------------------------