@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0877: (2016-03-19 )
MKLIINENEQLVAETVSRRIIELVKEKPASLICIAGGDTPLLTIEALIKANQAGEVDFSNTQFVGLDEWVGLGRETKGSCIQTLYDAFFDRLKNVSSEQICFFDGKATSLTDECARVDKFIDDRGGMDFILLGIGLNGHIGFNEPFVPVDVNCHVVELDDVTKRVMSKYFDTDLPLTHGISLGMQQILAAKEIFLVATGEKKIDIVKQVVEKEPTVAIPATLVKDSNTMLVVDKIAASGVEA
Atome Classification :
(22 SA)
.........10........20...-----.-----.-----...30---.........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160-.......170--....--.--..180.......190.......200.......210.......220..-.-....230.......240--------------------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
K
L
I
INE
N
E
Q
L
V
A
E
T
V
S
R
R
I
I
E
L
V
-----
K
-----E-----KPA
S
----
L
I
C
I
AGGDT
P
L
L
T
I
E
A
L
I
KANQAGEVDFSN
T
Q
F
V
G
L
D
E
W
VGLGRETK
G
S
C
I
Q
T
L
Y
D
A
F
F
D
R
L
KNVSSE
Q
I
C
F
FDGKATS
L
T
D
E
C
A
R
V
D
K
F
I
DDRGG
M
D
F
I
L
L
G
I
GLNGHIGFNEP
F
V
P
V
D
V
N
C
H
V
V
E
L
D
D
V
T
-
K
R
V
M
S
K
YFDT--DLP
L
--
T
--
H
G
I
S
L
G
M
Q
Q
I
L
A
AK
E
I
F
L
V
ATGE
K
K
I
D
I
V
K
Q
V
V
EKEP
T
V
A
I
P
A
T
L
VK-D-S
N
T
M
L
V
V
D
K
I
A
ASGVEA--------------------------------
38
HHSearch
93.80
32%
-125
- C3 -
2BKX
1
NAGB_BACSU
A:
[1-242]
M
K
V
M
E
C
Q
T
Y
E
E
L
S
Q
I
A
A
R
I
T
A
D
T
I
-----
K
-----
E
-----
K
P
D
A
----
V
L
G
L
A
T
G
G
T
P
E
G
T
Y
R
Q
L
I
R
L
H
Q
T
E
N
L
S
F
Q
N
I
T
T
V
N
L
D
E
Y
A
G
L
S
S
D
D
P
N
S
Y
H
F
Y
M
N
D
R
F
F
Q
H
I
-
D
S
K
P
S
R
H
F
I
P
N
G
N
A
D
D
L
E
A
E
C
R
R
Y
E
Q
L
V
D
S
L
G
D
T
D
I
Q
L
L
G
I
G
R
N
G
H
I
G
F
N
E
P
G
T
S
F
K
S
R
T
H
V
V
T
L
N
E
Q
T
R
Q
-
A
N
A
R
Y
F
P
S
I-
D
S
V
P
--
K
--
K
A
L
T
M
G
I
Q
T
I
L
S
S
K
R
I
L
L
L
I
S
G
K
S
K
A
E
A
V
R
K
L
L
E
G
N
I
S
E
D
F
P
A
S
A
L
H
L
H
-
S
D
V
T
V
L
I
D
R
E
A
A
S
L
R
P
---------------------------------
2
PsiBlast_PDB
93.55
32%
-117
- C3 -
2BKX
1
NAGB_BACSU
A:
[1-239]
M
K
V
M
E
C
Q
T
Y
E
E
L
S
Q
I
A
A
R
I
T
A
D
T
I
-----
K
-----
E
-----
K
P
D
A
----
V
L
G
L
A
T
G
G
T
P
E
G
T
Y
R
Q
L
I
R
L
H
Q
T
E
N
L
S
F
Q
N
I
T
T
V
N
L
D
E
Y
A
G
L
S
S
D
D
P
N
S
Y
H
F
Y
M
N
D
R
F
F
Q
H
I
D
S
K
P
S
R
H
F
-
I
P
N
G
N
A
D
D
L
E
A
E
C
R
R
Y
E
Q
L
V
D
S
L
G
D
T
D
I
Q
L
L
G
I
G
R
N
G
H
I
G
F
N
E
P
G
T
S
F
K
S
R
T
H
V
V
T
L
N
E
Q
T
-
R
Q
A
N
A
R
Y
F
P
S
I-
D
S
V
P
--
K
--
K
A
L
T
M
G
I
Q
T
I
L
S
S
K
R
I
L
L
L
I
S
G
K
S
K
A
E
A
V
R
K
L
L
E
G
N
I
S
E
D
F
P
A
S
A
L
H
L
H
-
S
D
V
T
V
L
I
D
R
E
A
A
S
------------------------------------
22
PsiBlast_CBE
92.99
32%
-118
- C3 -
2BKV
1
NAGB_BACSU
B:
[1-239]
M
K
V
M
E
C
Q
T
Y
E
E
L
S
Q
I
A
A
R
I
T
A
D
T
I
-----
K
-----
E
-----
K
P
D
A
----
V
L
G
L
A
T
G
G
T
P
E
G
T
Y
R
Q
L
I
R
L
H
Q
T
E
N
L
S
F
Q
N
I
T
T
V
N
L
D
E
Y
A
G
L
S
S
D
D
P
N
S
Y
H
F
Y
M
N
D
R
F
F
Q
H
I
D
S
K
P
S
R
H
F
-
I
P
N
G
N
A
D
D
L
E
A
E
C
R
R
Y
E
Q
L
V
D
S
L
G
D
T
D
I
Q
L
L
G
I
G
R
N
G
H
I
G
F
N
E
P
G
T
S
F
K
S
R
T
H
V
V
T
L
N
E
Q
T
-
R
Q
A
N
A
R
Y
F
P
S
I-
D
S
V
P
--
K
--
K
A
L
T
M
G
I
Q
T
I
L
S
S
K
R
I
L
L
L
I
S
G
K
S
K
A
E
A
V
R
K
L
L
E
G
N
I
S
E
D
F
P
A
S
A
L
H
L
H
-
S
D
V
T
V
L
I
D
R
E
A
A
S
------------------------------------
1
PsiBlast_PDB
92.23
32%
-116
- C3 -
2BKV
1
NAGB_BACSU
A:
[1-239]
M
K
V
M
E
C
Q
T
Y
E
E
L
S
Q
I
A
A
R
I
T
A
D
T
I
-----
K
-----
E
-----
K
P
D
A
----
V
L
G
L
A
T
G
G
T
P
E
G
T
Y
R
Q
L
I
R
L
H
Q
T
E
N
L
S
F
Q
N
I
T
T
V
N
L
D
E
Y
A
G
L
S
S
D
D
P
N
S
Y
H
F
Y
M
N
D
R
F
F
Q
H
I
D
S
K
P
S
R
H
F
-
I
P
N
G
N
A
D
D
L
E
A
E
C
R
R
Y
E
Q
L
V
D
S
L
G
D
T
D
I
Q
L
L
G
I
G
R
N
G
H
I
G
F
N
E
P
G
T
S
F
K
S
R
T
H
V
V
T
L
N
E
Q
T
-
R
Q
A
N
A
R
Y
F
P
S
I-
D
S
V
P
--
K
--
K
A
L
T
M
G
I
Q
T
I
L
S
S
K
R
I
L
L
L
I
S
G
K
S
K
A
E
A
V
R
K
L
L
E
G
N
I
S
E
D
F
P
A
S
A
L
H
L
H
-
S
D
V
T
V
L
I
D
R
E
A
A
S
------------------------------------
21
PsiBlast_CBE
92.17
32%
-117
- C3 -
2BKX
1
NAGB_BACSU
B:
[1-239]
M
K
V
M
E
C
Q
T
Y
E
E
L
S
Q
I
A
A
R
I
T
A
D
T
I
-----
K
-----
E
-----
K
P
D
A
----
V
L
G
L
A
T
G
G
T
P
E
G
T
Y
R
Q
L
I
R
L
H
Q
T
E
N
L
S
F
Q
N
I
T
T
V
N
L
D
E
Y
A
G
L
S
S
D
D
P
N
S
Y
H
F
Y
M
N
D
R
F
F
Q
H
I
D
S
K
P
S
R
H
F
-
I
P
N
G
N
A
D
D
L
E
A
E
C
R
R
Y
E
Q
L
V
D
S
L
G
D
T
D
I
Q
L
L
G
I
G
R
N
G
H
I
G
F
N
E
P
G
T
S
F
K
S
R
T
H
V
V
T
L
N
E
Q
T
-
R
Q
A
N
A
R
Y
F
P
S
I-
D
S
V
P
--
K
--
K
A
L
T
M
G
I
Q
T
I
L
S
S
K
R
I
L
L
L
I
S
G
K
S
K
A
E
A
V
R
K
L
L
E
G
N
I
S
E
D
F
P
A
S
A
L
H
L
H
-
S
D
V
T
V
L
I
D
R
E
A
A
S
------------------------------------
39
HHSearch
89.14
23%
-125
- C3 -
3HN6
1
NAGB_BORBU
A:
[22-269]
M
R
L
I
I
R
P
T
Y
E
D
I
S
K
W
A
A
N
H
V
A
Q
K
I
-----
N
E
F
SPT
K
-----
E
N
P
F
----
I
L
G
L
P
T
G
S
S
P
I
G
M
Y
K
N
L
I
E
L
N
K
N
K
K
I
S
F
Q
N
V
I
T
F
N
M
D
E
Y
I
G
I
E
E
N
H
P
E
S
Y
H
S
F
M
W
N
N
F
F
S
H
I
-
D
I
K
K
E
N
I
N
I
L
N
G
N
A
S
N
L
K
K
E
C
E
E
Y
E
K
K
I
K
S
F
G
G
I
M
L
F
V
G
G
I
G
P
D
G
H
I
A
F
N
E
P
G
S
S
L
T
S
R
T
R
I
K
T
L
T
Q
D
T
-
I
I
A
N
S
R
F
F
E
G
DV
N
K
V
P
--
K
--
N
A
L
T
V
G
I
G
T
I
M
D
S
Q
E
V
L
I
I
V
N
G
H
N
K
A
R
A
L
K
H
A
I
E
K
G
V
N
H
M
W
T
I
S
A
L
Q
L
H
-
K
N
A
I
I
V
S
D
K
N
A
T
Y
E
L
K
---------------------------------
29
Fugue
88.61
26%
-123
- C3 -
1NE7
4
GNPI1_HUMAN
A:
[1-281]
M
K
L
I
I
L
E
H
Y
S
Q
A
S
E
W
A
A
K
Y
I
R
N
R
I
-----
I
-----
Q
F
NPGP
E
K
Y
F
----
T
L
G
L
P
T
G
S
T
P
L
G
C
Y
K
K
L
I
E
Y
Y
K
N
G
D
L
S
F
K
Y
V
K
T
F
N
M
D
E
Y
V
G
L
P
R
D
H
P
E
S
Y
H
S
F
M
W
N
N
F
F
K
H
I
-
D
I
H
P
E
N
T
H
I
L
D
G
N
A
V
D
L
Q
A
E
C
D
A
F
E
E
K
I
K
A
A
G
G
I
E
L
F
V
G
G
I
G
P
D
G
H
I
A
F
N
E
P
G
S
S
L
V
S
R
T
R
V
K
T
L
A
M
D
T
-
I
L
A
N
A
R
F
F
D
G
--
E
L
T
K
VP
T
--
M
A
L
T
V
G
V
G
T
V
M
D
A
R
E
V
M
I
L
I
T
G
A
H
K
A
F
A
L
Y
K
A
I
E
E
G
V
N
H
M
W
T
V
S
A
F
Q
-
Q
H
P
R
T
V
F
V
C
D
E
D
A
T
L
E
L
K
V
K
T
V
K
Y
F
K
G
L
M
LVHNKLVDPLYSIKEKETEKSQ
40
HHSearch
88.33
26%
-121
* C3 *
1NE7
4
GNPI1_HUMAN
A:
[1-248]
M
K
L
I
I
L
E
H
Y
S
Q
A
S
E
W
A
A
K
Y
I
R
N
R
I
-----
I
-----
Q
F
NPGP
E
K
Y
F
----
T
L
G
L
P
T
G
S
T
P
L
G
C
Y
K
K
L
I
E
Y
Y
K
N
G
D
L
S
F
K
Y
V
K
T
F
N
M
D
E
Y
V
G
L
P
R
D
H
P
E
S
Y
H
S
F
M
W
N
N
F
F
K
H
I
-
D
I
H
P
E
N
T
H
I
L
D
G
N
A
V
D
L
Q
A
E
C
D
A
F
E
E
K
I
K
A
A
G
G
I
E
L
F
V
G
G
I
G
P
D
G
H
I
A
F
N
E
P
G
S
S
L
V
S
R
T
R
V
K
T
L
A
M
D
T
I
L
A
-
N
A
R
F
F
D
G
EL
T
K
V
P
--
T
--
M
A
L
T
V
G
V
G
T
V
M
D
A
R
E
V
M
I
L
I
T
G
A
H
K
A
F
A
L
Y
K
A
I
E
E
G
V
N
H
M
W
T
V
S
A
F
Q
Q
H
-
P
R
T
V
F
V
C
D
E
D
A
T
L
E
L
K
---------------------------------
44
HHSearch
87.82
30%
-130
- C3 -
2RI0
1
NAGB_STRMU
A:
[2-234]
M
K
T
I
K
V
K
N
K
T
E
G
S
K
V
A
F
R
M
L
E
E
E
I
-----
T
-----
F
------
G
A
K
----
T
L
G
L
A
T
G
S
T
P
L
E
L
Y
K
E
I
R
E
S
----
H
L
D
F
S
D
M
V
S
I
N
L
D
E
Y
V
G
L
S
A
D
D
K
Q
S
Y
A
Y
F
M
K
Q
N
L
F
A
A
K
-
P
F
K
K
S
Y
L
P
N
G
L
A
A
-
D
L
-
A
K
E
T
E
Y
Y
D
Q
I
L
A
Q
-
Y
P
I
D
L
Q
I
L
G
I
G
R
N
A
H
I
G
F
N
E
P
G
T
A
F
S
S
Q
T
H
L
V
D
L
T
P
S
T
I
A
A
N
-
S
R
F
F
E
K
A-
E
D
V
P
--
K
--
Q
A
I
S
M
G
L
A
S
I
M
S
A
K
M
I
L
L
M
A
F
G
E
E
K
A
E
A
V
A
A
M
V
K
G
P
V
T
E
E
I
P
A
S
I
L
Q
T
H
-
P
K
V
I
L
I
V
D
E
K
A
G
A
G
I
----------------------------------
28
Fugue
87.31
24%
-124
- C3 -
1DEA
2
NAGB_ECOLI
A:
[1-266]
M
R
L
I
P
L
T
T
A
E
Q
V
G
K
W
A
A
R
H
I
V
N
R
I
-----
N
-----
A
F
KPTA
D
R
P
F
----
V
L
G
L
P
T
G
G
T
P
M
T
T
Y
K
A
L
V
E
M
H
K
A
G
Q
V
S
F
K
H
V
V
T
F
N
M
D
E
Y
V
G
L
P
K
E
H
P
E
S
Y
Y
S
F
M
H
R
N
F
F
D
H
V
-
D
I
P
A
E
N
I
N
L
L
N
G
N
A
P
D
I
D
A
E
C
R
Q
Y
E
E
K
I
R
S
Y
G
K
I
H
L
F
M
G
G
V
G
N
D
G
H
I
A
F
N
E
P
A
S
S
L
A
S
R
T
R
I
K
T
L
T
H
D
T
-
R
V
A
N
S
R
F
F
D
N
--
D
V
N
Q
VP
K
--
Y
A
L
T
V
G
V
G
T
L
L
D
A
E
E
V
M
I
L
V
L
G
S
Q
K
A
L
A
L
Q
A
A
V
E
G
C
V
N
H
M
W
T
I
S
C
L
Q
-
L
H
P
K
A
I
M
V
C
D
E
P
S
T
M
E
L
K
V
K
T
L
R
Y
F
N
E
L
E
A
ENIKGL---------------
37
HHSearch
86.61
24%
-124
- C3 -
1FS5
2
NAGB_ECOLI
A:
[1-248]
M
R
L
I
P
L
T
T
A
E
Q
V
G
K
W
A
A
R
H
I
V
N
R
I
N
A
F
KP
T
-----
A
-----
D
R
P
F
----
V
L
G
L
P
T
G
G
T
P
M
T
T
Y
K
A
L
V
E
M
H
K
A
G
Q
V
S
F
K
H
V
V
T
F
N
M
D
E
Y
V
G
L
P
K
E
H
P
E
S
Y
Y
S
F
M
H
R
N
F
F
D
H
V
-
D
I
P
A
E
N
I
N
L
L
N
G
N
A
P
D
I
D
A
E
C
R
Q
Y
E
E
K
I
R
S
Y
G
K
I
H
L
F
M
G
G
V
G
N
D
G
H
I
A
F
N
E
P
A
S
S
L
A
S
R
T
R
I
K
T
L
T
H
D
T
-
R
V
A
N
S
R
F
F
D
N
DV
N
Q
V
P
--
K
--
Y
A
L
T
V
G
V
G
T
L
L
D
A
E
E
V
M
I
L
V
L
G
S
Q
K
A
L
A
L
Q
A
A
V
E
G
C
V
N
H
M
W
T
I
S
C
L
Q
L
H
-
P
K
A
I
M
V
C
D
E
P
S
T
M
E
L
K
---------------------------------
10
PsiBlast_PDB
84.06
27%
-128
- C3 -
1FS6
-
NAGB_ECOLI
A:
[1-217]
M
R
L
I
P
L
T
T
A
E
Q
V
G
K
W
A
A
R
H
I
V
N
R
I
-----
N
-----
A
F
----
K
P
T
A
D
R
P
F
V
L
G
L
P
T
G
G
T
P
M
T
T
Y
K
A
L
V
E
M
H
K
A
G
Q
V
S
F
K
H
V
V
T
F
N
M
D
E
Y
V
G
L
P
K
E
H
P
E
S
Y
Y
S
F
M
H
R
N
F
F
D
H
V
-
D
I
P
A
E
N
I
N
L
L
N
G
N
A
P
D
I
D
A
E
C
R
Q
Y
E
E
K
I
R
S
Y
G
K
I
H
L
F
M
G
G
V
G
N
D
G
H
I
A
F
N
E
P
A
S
S
L
A
S
R
T
R
I
K
T
L
T
H
D
T
-
R
V
A
N
S
R
F
F
D
N
--
D
V
N
Q
--
V
PK
Y
A
L
T
V
G
V
G
T
L
L
D
A
E
E
V
M
I
L
V
L
G
S
Q
K
A
L
A
L
Q
A
A
V
E
-----------------------------------------------------------------
12
PsiBlast_PDB
83.87
27%
-125
- C3 -
2WU1
2
NAGB_ECOLI
A:
[1-217]
M
R
L
I
P
L
T
T
A
E
Q
V
G
K
W
A
A
R
H
I
V
N
R
I
-----
N
-----
A
F
----
K
P
T
A
D
R
P
F
V
L
G
L
P
T
G
G
T
P
M
T
T
Y
K
A
L
V
E
M
H
K
A
G
Q
V
S
F
K
H
V
V
T
F
N
M
D
E
Y
V
G
L
P
K
E
H
P
E
S
Y
Y
S
F
M
H
R
N
F
F
D
H
V
-
D
I
P
A
E
N
I
N
L
L
N
G
N
A
P
D
I
D
A
E
C
R
Q
Y
E
E
K
I
R
S
Y
G
K
I
H
L
F
M
G
G
V
G
N
D
G
H
I
A
F
N
E
P
A
S
S
L
A
S
R
T
R
I
K
T
L
T
H
D
T
-
R
V
A
N
S
R
F
F
D
N
--
D
V
N
Q
--
V
PK
Y
A
L
T
V
G
V
G
T
L
L
D
A
E
E
V
M
I
L
V
L
G
S
Q
K
A
L
A
L
Q
A
A
V
E
-----------------------------------------------------------------
6
PsiBlast_PDB
83.60
27%
-123
- C3 -
1CD5
-
NAGB_ECOLI
A:
[1-217]
M
R
L
I
P
L
T
T
A
E
Q
V
G
K
W
A
A
R
H
I
V
N
R
I
-----
N
-----
A
F
----
K
P
T
A
D
R
P
F
V
L
G
L
P
T
G
G
T
P
M
T
T
Y
K
A
L
V
E
M
H
K
A
G
Q
V
S
F
K
H
V
V
T
F
N
M
D
E
Y
V
G
L
P
K
E
H
P
E
S
Y
Y
S
F
M
H
R
N
F
F
D
H
V
-
D
I
P
A
E
N
I
N
L
L
N
G
N
A
P
D
I
D
A
E
C
R
Q
Y
E
E
K
I
R
S
Y
G
K
I
H
L
F
M
G
G
V
G
N
D
G
H
I
A
F
N
E
P
A
S
S
L
A
S
R
T
R
I
K
T
L
T
H
D
T
-
R
V
A
N
S
R
F
F
D
N
--
D
V
N
Q
--
V
PK
Y
A
L
T
V
G
V
G
T
L
L
D
A
E
E
V
M
I
L
V
L
G
S
Q
K
A
L
A
L
Q
A
A
V
E
-----------------------------------------------------------------
11
PsiBlast_PDB
83.51
27%
-126
- C3 -
1FSF
-
NAGB_ECOLI
A:
[1-217]
M
R
L
I
P
L
T
T
A
E
Q
V
G
K
W
A
A
R
H
I
V
N
R
I
-----
N
-----
A
F
----
K
P
T
A
D
R
P
F
V
L
G
L
P
T
G
G
T
P
M
T
T
Y
K
A
L
V
E
M
H
K
A
G
Q
V
S
F
K
H
V
V
T
F
N
M
D
E
Y
V
G
L
P
K
E
H
P
E
S
Y
Y
S
F
M
H
R
N
F
F
D
H
V
-
D
I
P
A
E
N
I
N
L
L
N
G
N
A
P
D
I
D
A
E
C
R
Q
Y
E
E
K
I
R
S
Y
G
K
I
H
L
F
M
G
G
V
G
N
D
G
H
I
A
F
N
E
P
A
S
S
L
A
S
R
T
R
I
K
T
L
T
H
D
T
-
R
V
A
N
S
R
F
F
D
N
--
D
V
N
Q
--
V
PK
Y
A
L
T
V
G
V
G
T
L
L
D
A
E
E
V
M
I
L
V
L
G
S
Q
K
A
L
A
L
Q
A
A
V
E
-----------------------------------------------------------------
9
PsiBlast_PDB
83.42
27%
-125
- C3 -
1FS5
2
NAGB_ECOLI
A:
[1-217]
M
R
L
I
P
L
T
T
A
E
Q
V
G
K
W
A
A
R
H
I
V
N
R
I
-----
N
-----
A
F
----
K
P
T
A
D
R
P
F
V
L
G
L
P
T
G
G
T
P
M
T
T
Y
K
A
L
V
E
M
H
K
A
G
Q
V
S
F
K
H
V
V
T
F
N
M
D
E
Y
V
G
L
P
K
E
H
P
E
S
Y
Y
S
F
M
H
R
N
F
F
D
H
V
-
D
I
P
A
E
N
I
N
L
L
N
G
N
A
P
D
I
D
A
E
C
R
Q
Y
E
E
K
I
R
S
Y
G
K
I
H
L
F
M
G
G
V
G
N
D
G
H
I
A
F
N
E
P
A
S
S
L
A
S
R
T
R
I
K
T
L
T
H
D
T
-
R
V
A
N
S
R
F
F
D
N
--
D
V
N
Q
--
V
PK
Y
A
L
T
V
G
V
G
T
L
L
D
A
E
E
V
M
I
L
V
L
G
S
Q
K
A
L
A
L
Q
A
A
V
E
-----------------------------------------------------------------
8
PsiBlast_PDB
83.42
27%
-124
- C3 -
1FRZ
1
NAGB_ECOLI
A:
[1-217]
M
R
L
I
P
L
T
T
A
E
Q
V
G
K
W
A
A
R
H
I
V
N
R
I
-----
N
-----
A
F
----
K
P
T
A
D
R
P
F
V
L
G
L
P
T
G
G
T
P
M
T
T
Y
K
A
L
V
E
M
H
K
A
G
Q
V
S
F
K
H
V
V
T
F
N
M
D
E
Y
V
G
L
P
K
E
H
P
E
S
Y
Y
S
F
M
H
R
N
F
F
D
H
V
-
D
I
P
A
E
N
I
N
L
L
N
G
N
A
P
D
I
D
A
E
C
R
Q
Y
E
E
K
I
R
S
Y
G
K
I
H
L
F
M
G
G
V
G
N
D
G
H
I
A
F
N
E
P
A
S
S
L
A
S
R
T
R
I
K
T
L
T
H
D
T
-
R
V
A
N
S
R
F
F
D
N
--
D
V
N
Q
--
V
PK
Y
A
L
T
V
G
V
G
T
L
L
D
A
E
E
V
M
I
L
V
L
G
S
Q
K
A
L
A
L
Q
A
A
V
E
-----------------------------------------------------------------
7
PsiBlast_PDB
83.40
27%
-124
- C3 -
1FQO
2
NAGB_ECOLI
A:
[1-217]
M
R
L
I
P
L
T
T
A
E
Q
V
G
K
W
A
A
R
H
I
V
N
R
I
-----
N
-----
A
F
----
K
P
T
A
D
R
P
F
V
L
G
L
P
T
G
G
T
P
M
T
T
Y
K
A
L
V
E
M
H
K
A
G
Q
V
S
F
K
H
V
V
T
F
N
M
D
E
Y
V
G
L
P
K
E
H
P
E
S
Y
Y
S
F
M
H
R
N
F
F
D
H
V
-
D
I
P
A
E
N
I
N
L
L
N
G
N
A
P
D
I
D
A
E
C
R
Q
Y
E
E
K
I
R
S
Y
G
K
I
H
L
F
M
G
G
V
G
N
D
G
H
I
A
F
N
E
P
A
S
S
L
A
S
R
T
R
I
K
T
L
T
H
D
T
-
R
V
A
N
S
R
F
F
D
N
--
D
V
N
Q
--
V
PK
Y
A
L
T
V
G
V
G
T
L
L
D
A
E
E
V
M
I
L
V
L
G
S
Q
K
A
L
A
L
Q
A
A
V
E
-----------------------------------------------------------------
5
PsiBlast_PDB
82.84
27%
-123
- C3 -
1HOT
2
NAGB_ECOLI
A:
[1-217]
M
R
L
I
P
L
T
T
A
E
Q
V
G
K
W
A
A
R
H
I
V
N
R
I
-----
N
-----
A
F
----
K
P
T
A
D
R
P
F
V
L
G
L
P
T
G
G
T
P
M
T
T
Y
K
A
L
V
E
M
H
K
A
G
Q
V
S
F
K
H
V
V
T
F
N
M
D
E
Y
V
G
L
P
K
E
H
P
E
S
Y
Y
S
F
M
H
R
N
F
F
D
H
V
-
D
I
P
A
E
N
I
N
L
L
N
G
N
A
P
D
I
D
A
E
C
R
Q
Y
E
E
K
I
R
S
Y
G
K
I
H
L
F
M
G
G
V
G
N
D
G
H
I
A
F
N
E
P
A
S
S
L
A
S
R
T
R
I
K
T
L
T
H
D
T
-
R
V
A
N
S
R
F
F
D
N
--
D
V
N
Q
--
V
PK
Y
A
L
T
V
G
V
G
T
L
L
D
A
E
E
V
M
I
L
V
L
G
S
Q
K
A
L
A
L
Q
A
A
V
E
-----------------------------------------------------------------
23
PsiBlast_CBE
82.39
32%
-125
- C3 -
2RI0
3
NAGB_STRMU
B:
[29-234]
-------------------------------------------
A
K
----
T
L
G
L
A
T
G
S
T
P
L
----
E
L
Y
K
E
I
R
E
S
H
L
D
F
S
D
M
V
S
I
N
L
D
E
Y
V
G
L
S
A
D
D
K
Q
S
Y
A
Y
F
M
K
Q
N
L
F
A
A
K
P
F
K
K
S
---
Y
L
P
N
G
L
A
A
D
L
A
K
E
T
E
Y
Y
D
Q
I
L
A
Q
Y
P
-
I
D
L
Q
I
L
G
I
G
R
N
A
H
I
G
F
N
E
P
G
T
A
F
S
S
Q
T
H
L
V
D
L
T
P
S
T
-
I
A
A
N
S
R
F
F
E
K
AE
D
V
P
---
K
--
Q
A
I
S
M
G
L
A
S
I
M
S
A
K
M
I
L
L
M
A
F
G
E
E
K
A
E
A
V
A
A
M
V
K
G
P
V
T
E
E
I
P
A
S
I
L
Q
T
H
-
P
K
V
I
L
I
V
D
E
K
A
G
A
G
I
----------------------------------
15
PsiBlast_PDB
81.25
32%
-127
- C3 -
2RI1
2
NAGB_STRMU
A:
[30-235]
-------------------------------------------
A
K
----
T
L
G
L
A
T
G
S
T
P
L
----
E
L
Y
K
E
I
R
E
S
H
L
D
F
S
D
M
V
S
I
N
L
D
E
Y
V
G
L
S
A
D
D
K
Q
S
Y
A
Y
F
M
K
Q
N
L
F
A
A
K
P
F
K
K
S
---
Y
L
P
N
G
L
A
A
D
L
A
K
E
T
E
Y
Y
D
Q
I
L
A
Q
Y
P
-
I
D
L
Q
I
L
G
I
G
R
N
A
H
I
G
F
N
E
P
G
T
A
F
S
S
Q
T
H
L
V
D
L
T
P
S
T
-
I
A
A
N
S
R
F
F
E
K
AE
D
V
P
---
K
--
Q
A
I
S
M
G
L
A
S
I
M
S
A
K
M
I
L
L
M
A
F
G
E
E
K
A
E
A
V
A
A
M
V
K
G
P
V
T
E
E
I
P
A
S
I
L
Q
T
H
-
P
K
V
I
L
I
V
D
E
K
A
G
A
G
I
----------------------------------
24
PsiBlast_CBE
80.25
32%
-122
- C3 -
2RI1
2
NAGB_STRMU
B:
[30-235]
-------------------------------------------
A
K
----
T
L
G
L
A
T
G
S
T
P
L
----
E
L
Y
K
E
I
R
E
S
H
L
D
F
S
D
M
V
S
I
N
L
D
E
Y
V
G
L
S
A
D
D
K
Q
S
Y
A
Y
F
M
K
Q
N
L
F
A
A
K
P
F
K
K
S
---
Y
L
P
N
G
L
A
A
D
L
A
K
E
T
E
Y
Y
D
Q
I
L
A
Q
Y
P
-
I
D
L
Q
I
L
G
I
G
R
N
A
H
I
G
F
N
E
P
G
T
A
F
S
S
Q
T
H
L
V
D
L
T
P
S
T
-
I
A
A
N
S
R
F
F
E
K
AE
D
V
P
---
K
--
Q
A
I
S
M
G
L
A
S
I
M
S
A
K
M
I
L
L
M
A
F
G
E
E
K
A
E
A
V
A
A
M
V
K
G
P
V
T
E
E
I
P
A
S
I
L
Q
T
H
-
P
K
V
I
L
I
V
D
E
K
A
G
A
G
I
----------------------------------