@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0986: (2016-03-20 )
MIKLTNVVKKFGKIEAVKGINLEVEKGSLFAFLGENGAGKSTTLSMICTESEPTSGEIYIDDEKLTFKNRKLFRQKLGVVFQENVLDDLLTVRENLYNRASLYGKTKAEITERLALVSSIMGIEDILNRRFEKLSGGQKRRAEIARAIMHDPEILLLDEPTTGLDPKTRVSVWKIIDYLREELGMTVFLTTHYLEEAKDADQLAVIHKGKIIAQGTPTNIRSRFSVDKIFFYDAKVAELQKIMKKANLPFKVSKATMRVDVITQDVEILAILNQAAGLYGSFEVIKGNLDDAFISMIKEESDD
Atome Classification :
(37 SA)
--.........--10--.----.----......20........30........40........50........60--------.....---.-------------.---.70.--.----...---...80.--------.......90.....------.---..100-.....----------..110....-.---..120-------..-....-.----.130.......140.......150.......160.......170.......180.......190-....-.-.-.----200.......210.......220----........---230.......240---........250.......260......-------------.270.......280.......290------........300.---------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
--MI
K
L
T
N
V
V
K
--
K
F--G----K----
I
E
A
VKG
I
N
L
E
V
EKG
S
L
F
A
F
LGENGAGKS
T
T
L
S
M
I
CTESEPTS
G
E
I
Y
ID--------DEKL
T
---
F
-------------
K
---
N
R
K
L
--
F
----
R
Q
K
---
L
G
V
V
F
Q
--------
E
N
V
L
D
D
L
L
T
V
R
E
N
L
------
Y
---
N
R
A
S
L-YG
K
T
K
----------
A
E
I
T
E
R
L
A
L
-
V
---
S
S
I
M
--------
G
I
-
E
D
I
L
-
N
----
R
R
F
E
KLSGG
Q
K
R
R
A
E
I
A
R
A
I
MHDP
E
I
L
L
L
DEPTTGLDP
K
T
R
V
S
V
W
K
I
I
D
Y
L
R
E
ELG
M
T
V
F
L
T
T
H
-
Y
L
E
E
-A-K-D----AD
Q
L
A
V
I
HK
G
K
I
I
AQGTPT
N
I
-
R
----SRFSV
D
K
I
---
F
FYD
A
K
V
A
E
L
Q
K
----
I
M
K
KANL
P
F
K
VSK
A
T
M
R
V
D
V
I
TQ
D
V
E
I
-------------
L
A
I
L
N
Q
AAGLYG
S
F
E
V
IKGNL
D
D
-------
A
F
I
S
M
I
K
EESDD---------------------
113
Fugue
81.39
28%
-80
- C1 -
3TUZ
3
METN_ECOLI
H:
[23-362]
-H
M
I
K
L
S
N
I
T
K
--
V
F
--
H
QGTR
T
----
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
--------
G
Q
E
L
T
TLS
E
-------------
S
---
E
L
T
K
--
A
----
R
R
Q
---
I
G
M
I
F
Q
--------
H
F
N
L
L
S
S
R
T
V
F
G
N
V
------
A
---
L
P
L
E
L
-
D
N
T
P
K
----------
D
E
V
K
R
R
V
T
E
-
L
---
L
S
L
V
--------
G
L
-
G
D
K
H
-
D
----
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
-
E
M
D
V
-
V
-
K
-
R
I---
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
-
F
----
S
H
P
K
T
P
L
A
---
Q
K
F
I
Q
S
T
L
H
L
D
I
PEDY
Q
E
R
L
Q
A
E
P
F
T
D
C
V
P
M
L
R
L
E
F
T
G
Q
S
V
D
A
-------------
P
L
L
S
E
T
A
R
R
F
N
V
N
N
N
I
I
S
A
Q
M
D
Y
AGGVKFG
I
M
L
T
E
M
H
G
T
Q
Q
D
TQAAIAWLQEHHVKVEV----
27
PsiBlast_CBE
78.89
38%
-88
- C1 -
4YMU
2
?
A:
[1-226]
--
M
I
F
V
N
D
V
Y
K
--
N
F
--
G
----
S
----
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
--------
G
V
K
I
N
---
N
-------------
G
KV-
N
I
N
K
--
V
----
R
Q
K
---
V
G
M
V
F
Q
--------
H
F
N
L
F
P
H
L
T
A
I
E
N
I
------
T
---
L
A
P
V
K
-
V
K
K
M
N
----------
K
K
E
A
E
E
L
A
V
D
L
---
L
A
K
V
--------
G
L
-
L
D
K
K
-
D
----
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
-
E
M
G
F
-
A
-
R
-
E
V---
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
-
F
----
Y
R
--------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
78.85
38%
-88
- C1 -
4YMU
2
?
J:
[1-226]
--
M
I
F
V
N
D
V
Y
K
--
N
F
--
G
----
S
----
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
--------
G
V
K
I
N
---
N
-------------
G
KV-
N
I
N
K
--
V
----
R
Q
K
---
V
G
M
V
F
Q
--------
H
F
N
L
F
P
H
L
T
A
I
E
N
I
------
T
---
L
A
P
V
K
-
V
K
K
M
N
----------
K
K
E
A
E
E
L
A
V
D
L
---
L
A
K
V
--------
G
L
-
L
D
K
K
-
D
----
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
-
E
M
G
F
-
A
-
R
-
E
V---
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
-
F
----
Y
R
--------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
78.13
38%
-90
- C1 -
4YMS
-
?
J:
[1-226]
--
M
I
F
V
N
D
V
Y
K
--
N
F
--
G
----
S
----
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
--------
G
V
K
I
N
---
N
-------------
G
KV-
N
I
N
K
--
V
----
R
Q
K
---
V
G
M
V
F
Q
--------
H
F
N
L
F
P
H
L
T
A
I
E
N
I
------
T
---
L
A
P
V
K
-
V
K
K
M
N
----------
K
K
E
A
E
E
L
A
V
D
L
---
L
A
K
V
--------
G
L
-
L
D
K
K
-
D
----
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
-
E
M
G
F
-
A
-
R
-
E
V---
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
-
F
----
Y
R
--------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
77.81
38%
-89
- C1 -
4YMW
-
?
J:
[1-226]
--
M
I
F
V
N
D
V
Y
K
--
N
F
--
G
----
S
----
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
--------
G
V
K
I
N
---
N
-------------
G
KV-
N
I
N
K
--
V
----
R
Q
K
---
V
G
M
V
F
Q
--------
H
F
N
L
F
P
H
L
T
A
I
E
N
I
------
T
---
L
A
P
V
K
-
V
K
K
M
N
----------
K
K
E
A
E
E
L
A
V
D
L
---
L
A
K
V
--------
G
L
-
L
D
K
K
-
D
----
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
-
E
M
G
F
-
A
-
R
-
E
V---
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
-
F
----
Y
R
--------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
77.61
38%
-88
- C1 -
4YMV
1
?
A:
[1-226]
--
M
I
F
V
N
D
V
Y
K
--
N
F
--
G
----
S
----
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
--------
G
V
K
I
N
---
N
-------------
G
KV-
N
I
N
K
--
V
----
R
Q
K
---
V
G
M
V
F
Q
--------
H
F
N
L
F
P
H
L
T
A
I
E
N
I
------
T
---
L
A
P
V
K
-
V
K
K
M
N
----------
K
K
E
A
E
E
L
A
V
D
L
---
L
A
K
V
--------
G
L
-
L
D
K
K
-
D
----
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
-
E
M
G
F
-
A
-
R
-
E
V---
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
-
F
----
Y
R
--------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
77.52
40%
-85
- C1 -
2IT1
-
?
A:
[4-221]
---
I
K
L
E
N
I
V
K
--
K
F
--
G
----
N
----
F
T
A
L
N
N
I
N
L
K
I
K
D
G
E
F
M
A
L
L
G
P
S
G
S
G
K
S
T
L
L
Y
T
I
A
G
I
Y
K
P
T
S
G
K
I
Y
F
D
--------
E
K
D
V
T
---
E
-------------
L
---
P
P
K
--------
D
R
N
---
V
G
L
V
F
Q
--------
N
W
A
L
Y
P
H
M
T
V
Y
K
N
I
------
A
---
F
P
L
E
L
-
R
K
A
P
R
----------
E
E
I
D
K
K
V
R
E
-
V
---
A
K
M
L
--------
H
I
-
D
K
L
L
-
N
----
R
Y
P
W
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
V
K
E
P
E
V
L
L
L
D
E
P
L
S
N
L
D
A
L
L
R
L
E
V
R
A
E
L
K
R
L
Q
K
E
L
G
I
T
T
V
Y
V
T
H
-
D
Q
A
E
-
A
L
A
-
M
----
A
D
R
I
A
V
I
R
E
G
E
I
L
Q
V
G
T
P
D
E
V
----------------------------------------------------------------------------------------------------------------------------------------
124
HHSearch
77.51
40%
-86
- C1 -
2IT1
-
?
A:
[3-224]
--
E
I
K
L
E
N
I
V
K
--
K
F
--
G
----
N
----
F
T
A
L
N
N
I
N
L
K
I
K
D
G
E
F
M
A
L
L
G
P
S
G
S
G
K
S
T
L
L
Y
T
I
A
G
I
Y
K
P
T
S
G
K
I
Y
F
D
--------
E
K
D
V
T
---
E
------------------
L
P
P
--
K
----
D
R
N
---
V
G
L
V
F
Q
--------
N
W
A
L
Y
P
H
M
T
V
Y
K
N
I
------
A
---
F
P
L
E
L
-
R
K
A
P
R
----------
E
E
I
D
K
K
V
R
E
-
V
---
A
K
M
L
--------
H
I
-
D
K
L
L
-
N
----
R
Y
P
W
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
V
K
E
P
E
V
L
L
L
D
E
P
L
S
N
L
D
A
L
L
R
L
E
V
R
A
E
L
K
R
L
Q
K
E
L
G
I
T
T
V
Y
V
T
H
-
D
Q
A
E
-
A
-
L
A
M
----
A
D
R
I
A
V
I
R
E
G
E
I
L
Q
V
G
T
P
D
E
V
-
Y
----
Y
K
--------------------------------------------------------------------------------------------------------------------------------
115
Fugue
77.22
29%
-79
- C1 -
1OXS
23
?
C:
[1-352]
MV
R
I
I
V
K
N
V
S
K
--
V
F
KK
G
----
K
----
V
V
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
F
D
--------
D
R
L
V
A
---
S
-------------
N
---
G
K
L
I
--
V
----
P
P
E
DRK
I
G
M
V
F
Q
--------
T
W
A
L
Y
P
N
L
T
A
F
E
N
I
------
A
---
F
P
L
T
N
-
M
K
M
S
K
----------
E
E
I
R
K
R
V
E
E
-
V
---
A
K
I
L
--------
D
I
-
H
H
V
L
-
N
----
H
F
P
R
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
Q
S
R
L
G
V
T
L
L
V
V
S
H
-
D
P
A
D
-
I
-
F
-
A
I---
A
D
R
V
G
V
L
V
K
G
K
L
V
Q
V
G
K
P
E
D
L
-
Y
DNPV
S
I
Q
V
A
S
L
I
GEI
N
E
L
E
G
K
V
T
N
E
G
V
----
V
I
G
S
L
R
F
P
V
S
V
S
S
D
R
A
I
I
G
I
R
P
E
D
V
K
L
SKDVIKDDSWILV
G
K
G
K
V
K
V
I
G
Y
Q
G
G
L
F
R
I
T
I
T
P
L
D
-------
S
E
E
E
I
F
T
Y
S
D
H
P
IHSGEEVLVYVRKDKIKVFEK
10
PsiBlast_PDB
77.11
36%
-85
- C1 -
1OXV
7
?
A:
[4-228]
---
I
I
V
K
N
V
S
K
--
V
F
KK
G
----
K
----
V
V
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
F
D
--------
D
-
R
L
V
---
A
-------------
S
---
N
G
K
L
--
I
VPPE
D
R
K
---
I
G
M
V
F
Q
--------
T
W
A
L
Y
P
N
L
T
A
F
E
N
I
------
A
---
F
P
L
T
N
-
M
K
M
S
K
----------
E
E
I
R
K
R
V
E
E
-
V
---
A
K
I
L
--------
D
I
-
H
H
V
L
-
N
----
H
F
P
R
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
Q
S
R
L
G
V
T
L
L
V
V
S
H
----
D
-
P
-
A
-
D
I
F
A
I
A
D
R
V
G
V
L
V
K
G
K
L
V
Q
V
G
K
P
E
D
L
----------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
77.04
38%
-88
- C1 -
4YMV
1
?
J:
[1-226]
--
M
I
F
V
N
D
V
Y
K
--
N
F
--
G
----
S
----
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
--------
G
V
K
I
N
---
N
-------------
G
KV-
N
I
N
K
--
V
----
R
Q
K
---
V
G
M
V
F
Q
--------
H
F
N
L
F
P
H
L
T
A
I
E
N
I
------
T
---
L
A
P
V
K
-
V
K
K
M
N
----------
K
K
E
A
E
E
L
A
V
D
L
---
L
A
K
V
--------
G
L
-
L
D
K
K
-
D
----
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
-
E
M
G
F
-
A
-
R
-
E
V---
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
-
F
----
Y
R
--------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
76.87
38%
-89
- C1 -
4YMT
-
?
J:
[1-226]
--
M
I
F
V
N
D
V
Y
K
--
N
F
--
G
----
S
----
L
E
V
L
K
G
V
T
L
K
V
N
K
G
E
V
V
V
I
I
G
P
S
G
S
G
K
S
T
L
L
R
C
I
N
L
L
E
E
P
T
K
G
E
V
F
I
D
--------
G
V
K
I
N
---
N
-------------
G
KV-
N
I
N
K
--
V
----
R
Q
K
---
V
G
M
V
F
Q
--------
H
F
N
L
F
P
H
L
T
A
I
E
N
I
------
T
---
L
A
P
V
K
-
V
K
K
M
N
----------
K
K
E
A
E
E
L
A
V
D
L
---
L
A
K
V
--------
G
L
-
L
D
K
K
-
D
----
Q
Y
P
I
K
L
S
G
G
Q
K
Q
R
L
A
I
A
R
A
L
A
M
Q
P
E
V
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
K
E
V
L
N
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
-
E
M
G
F
-
A
-
R
-
E
V---
G
D
R
V
I
F
M
D
D
G
V
I
V
E
E
G
T
P
E
E
I
-
F
----
Y
R
--------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
76.77
36%
-91
- C1 -
1OXV
15
?
D:
[4-228]
---
I
I
V
K
N
V
S
K
--
V
F
KK
G
----
K
----
V
V
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
F
D
--------
D
-
R
L
V
---
A
-------------
S
---
N
G
K
L
--
I
VPPE
D
R
K
---
I
G
M
V
F
Q
--------
T
W
A
L
Y
P
N
L
T
A
F
E
N
I
------
A
---
F
P
L
T
N
-
M
K
M
S
K
----------
E
E
I
R
K
R
V
E
E
-
V
---
A
K
I
L
--------
D
I
-
H
H
V
L
-
N
----
H
F
P
R
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
Q
S
R
L
G
V
T
L
L
V
V
S
H
----
D
-
P
-
A
-
D
IFAI
A
D
R
V
G
V
L
V
K
G
K
L
V
Q
V
G
K
P
E
D
L
----------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
76.53
36%
-86
- C1 -
1OXU
13
?
C:
[4-228]
---
I
I
V
K
N
V
S
K
--
V
F
KK
G
----
K
----
V
V
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
F
D
--------
D
-
R
L
V
---
A
-------------
S
---
N
G
K
L
--
I
VPPE
D
R
K
---
I
G
M
V
F
Q
--------
T
W
A
L
Y
P
N
L
T
A
F
E
N
I
------
A
---
F
P
L
T
N
-
M
K
M
S
K
----------
E
E
I
R
K
R
V
E
E
-
V
---
A
K
I
L
--------
D
I
-
H
H
V
L
-
N
----
H
F
P
R
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
Q
S
R
L
G
V
T
L
L
V
V
S
H
----
D
-
P
-
A
-
D
IFAI
A
D
R
V
G
V
L
V
K
G
K
L
V
Q
V
G
K
P
E
D
L
----------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
76.49
36%
-87
- C1 -
1OXV
4
?
B:
[4-228]
---
I
I
V
K
N
V
S
K
--
V
F
KK
G
----
K
----
V
V
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
F
D
--------
D
-
R
L
V
---
A
-------------
S
---
N
G
K
L
--
I
VPPE
D
R
K
---
I
G
M
V
F
Q
--------
T
W
A
L
Y
P
N
L
T
A
F
E
N
I
------
A
---
F
P
L
T
N
-
M
K
M
S
K
----------
E
E
I
R
K
R
V
E
E
-
V
---
A
K
I
L
--------
D
I
-
H
H
V
L
-
N
----
H
F
P
R
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
Q
S
R
L
G
V
T
L
L
V
V
S
H
----
D
-
P
-
A
-
D
IFAI
A
D
R
V
G
V
L
V
K
G
K
L
V
Q
V
G
K
P
E
D
L
----------------------------------------------------------------------------------------------------------------------------------------
129
HHSearch
76.44
34%
-80
- C1 -
1OXX
21
?
K:
[3-233]
--
R
I
I
V
K
N
V
S
K
--
V
F
--
K
----
K
GK--
V
V
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
F
D
--------
D
R
L
V
A
---
S
-------------
N
GKL
I
V
P
P
--
E
----
D
R
K
---
I
G
M
V
F
Q
--------
T
W
A
L
Y
P
N
L
T
A
F
E
N
I
------
A
---
F
P
L
T
N
-
M
K
M
S
K
----------
E
E
I
R
K
R
V
E
E
-
V
---
A
K
I
L
--------
D
I
-
H
H
V
L
-
N
----
H
F
P
R
E
L
S
G
A
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
Q
S
R
L
G
V
T
L
L
V
V
S
H
-
D
P
A
D
-
I
-
F
A
I
----
A
D
R
V
G
V
L
V
K
G
K
L
V
Q
V
G
K
P
E
D
L
-
Y
----
D
N
P
V
------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
76.25
40%
-85
- C1 -
2IT1
1
?
B:
[4-221]
---
I
K
L
E
N
I
V
K
--
K
F
--
G
----
N
----
F
T
A
L
N
N
I
N
L
K
I
K
D
G
E
F
M
A
L
L
G
P
S
G
S
G
K
S
T
L
L
Y
T
I
A
G
I
Y
K
P
T
S
G
K
I
Y
F
D
--------
E
K
D
V
T
---
E
-------------
L
---
P
P
K
--------
D
R
N
---
V
G
L
V
F
Q
--------
N
W
A
L
Y
P
H
M
T
V
Y
K
N
I
------
A
---
F
P
L
E
L
-
R
K
A
P
R
----------
E
E
I
D
K
K
V
R
E
-
V
---
A
K
M
L
--------
H
I
-
D
K
L
L
-
N
----
R
Y
P
W
Q
L
S
G
G
Q
Q
Q
R
V
A
I
A
R
A
L
V
K
E
P
E
V
L
L
L
D
E
P
L
S
N
L
D
A
L
L
R
L
E
V
R
A
E
L
K
R
L
Q
K
E
L
G
I
T
T
V
Y
V
T
H
-
D
Q
A
E
-
A
L
A
-
M
----
A
D
R
I
A
V
I
R
E
G
E
I
L
Q
V
G
T
P
D
E
V
----------------------------------------------------------------------------------------------------------------------------------------
141
HHSearch
76.09
31%
-86
- C1 -
1B0U
4
HISP_SALTY
A:
[7-245]
---
L
H
V
I
D
L
H
K
--
R
Y
--
G
----
G
----
H
E
V
L
K
G
V
S
L
Q
A
R
A
G
D
V
I
S
I
I
G
S
S
G
S
G
K
S
T
F
L
R
C
I
N
F
L
E
K
P
S
E
G
A
I
I
V
N
--------
G
Q
N
I
N
---
L
V
R
D
KDGQLKVAD
K
N
---
Q
L
R
L
--
L
----
R
T
R
---
L
T
M
V
F
Q
--------
H
F
N
L
W
S
H
M
T
V
L
E
N
V
------
M
---
E
A
P
I
Q
V
L
G
L
S
K
----------
H
D
A
R
E
R
A
L
K
-
Y
---
L
A
K
V
--------
G
I
-
D
E
R
A
Q
G
----
K
Y
P
V
H
L
S
G
G
Q
Q
Q
R
V
S
I
A
R
A
L
A
M
E
P
D
V
L
L
F
D
E
P
T
S
A
L
D
P
E
L
V
G
E
V
L
R
I
M
Q
Q
L
A
E
-
E
G
K
T
M
V
V
V
T
H
-
E
M
G
F
-
A
-
R
H
V
----
S
S
H
V
I
F
L
H
Q
G
K
I
E
E
E
G
D
P
E
Q
V
-
F
----
G
N
P
Q
------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
75.89
36%
-86
- C1 -
1OXU
7
?
A:
[4-228]
---
I
I
V
K
N
V
S
K
--
V
F
KK
G
----
K
----
V
V
A
L
D
N
V
N
I
N
I
E
N
G
E
R
F
G
I
L
G
P
S
G
A
G
K
T
T
F
M
R
I
I
A
G
L
D
V
P
S
T
G
E
L
Y
F
D
--------
D
-
R
L
V
---
A
-------------
S
---
N
G
K
L
--
I
VPPE
D
R
K
---
I
G
M
V
F
Q
--------
T
W
A
L
Y
P
N
L
T
A
F
E
N
I
------
A
---
F
P
L
T
N
-
M
K
M
S
K
----------
E
E
I
R
K
R
V
E
E
-
V
---
A
K
I
L
--------
D
I
-
H
H
V
L
-
N
----
H
F
P
R
E
L
S
G
G
Q
Q
Q
R
V
A
L
A
R
A
L
V
K
D
P
S
L
L
L
L
D
E
P
F
S
N
L
D
A
R
M
R
D
S
A
R
A
L
V
K
E
V
Q
S
R
L
G
V
T
L
L
V
V
S
H
----
D
-
P
-
A
-
D
I
F
A
I
A
D
R
V
G
V
L
V
K
G
K
L
V
Q
V
G
K
P
E
D
L
----------------------------------------------------------------------------------------------------------------------------------------
55
PsiBlast_CBE
75.78
33%
-93
- C1 -
3TUI
1
METN_ECOLI
C:
[24-254]
--
M
I
K
L
S
N
I
T
K
--
V
F
--
H
----
Q
GTRT
I
Q
A
L
N
N
V
S
L
H
V
P
A
G
Q
I
Y
G
V
I
G
A
S
G
A
G
K
S
T
L
I
R
C
V
N
L
L
E
R
P
T
E
G
S
V
L
V
D
--------
G
Q
E
L
T
---
T
-------------
L
---
S
E
S
E
--
L
TKA-
R
R
Q
---
I
G
M
I
F
Q
--------
H
F
N
L
L
S
S
R
T
V
F
G
N
V
------
A
---
L
P
L
E
L
-
D
N
T
P
K
----------
D
E
V
K
R
R
V
T
E
-
L
---
L
S
L
V
--------
G
L
-
G
D
K
H
-
D
----
S
Y
P
S
N
L
S
G
G
Q
K
Q
R
V
A
I
A
R
A
L
A
S
N
P
K
V
L
L
C
D
Q
A
T
S
A
L
D
P
A
T
T
R
S
I
L
E
L
L
K
D
I
N
R
R
L
G
L
T
I
L
L
I
T
H
-
E
M
D
V
-
V
-
K
-
R
I---
C
D
C
V
A
V
I
S
N
G
E
L
I
E
Q
D
T
V
S
E
V
-
F
----
S
H
--------------------------------------------------------------------------------------------------------------------------------
83
PsiBlast_CBE
74.34
32%
-89
- C1 -
2OLK
2
?
B:
[24-262]
--
M
I
D
V
H
Q
L
K
K
--
S
F
--
G
----
S
----
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
--------
G
I
N
L
K
---
A
-------------
K
---
D
T
N
L
NK
V
----
R
E
E
---
V
G
M
V
F
Q
--------
R
F
N
L
F
P
H
M
T
V
L
N
N
I
------
T
LAP
M
K
V
R
K
-
W
P
R
E
K
----------
A
E
-
A
K
A
M
E
L
-
L
---
D
K
V
---------
G
L
-
K
D
K
A
-
H
----
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
-
E
M
G
F
-
A
-
R
-
E
V---
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
-
F
----
D
R
P
Q
H
E
R
T
---
K
A
F
L
S
K
V
----------------------------------------------------------------------------------------------------------------
81
PsiBlast_CBE
74.03
32%
-87
- C1 -
2OLK
1
?
D:
[24-262]
--
M
I
D
V
H
Q
L
K
K
--
S
F
--
G
----
S
----
L
E
V
L
K
G
I
N
V
H
I
R
E
G
E
V
V
V
V
I
G
P
S
G
S
G
K
S
T
F
L
R
C
L
N
L
L
E
D
F
D
E
G
E
I
I
I
D
--------
G
I
N
L
K
---
A
-------------
K
---
D
T
N
L
NK
V
----
R
E
E
---
V
G
M
V
F
Q
--------
R
F
N
L
F
P
H
M
T
V
L
N
N
I
------
T
LAP
M
K
V
R
K
-
W
P
R
E
K
----------
A
E
-
A
K
A
M
E
L
-
L
---
D
K
V
---------
G
L
-
K
D
K
A
-
H
----
A
Y
P
D
S
L
S
G
G
Q
A
Q
R
V
A
I
A
R
A
L
A
M
E
P
K
I
M
L
F
D
E
P
T
S
A
L
D
P
E
M
V
G
E
V
L
S
V
M
K
Q
L
A
N
E
-
G
M
T
M
V
V
V
T
H
-
E
M
G
F
-
A
-
R
-
E
V---
G
D
R
V
L
F
M
D
G
G
Y
I
I
E
E
G
K
P
E
D
L
-
F
----
D
R
P
Q
H
E
R
T
---
K
A
F
L
S
K
V
----------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
73.24
36%
-86
- C1 -
2D62
7
?
A:
[7-230]
---
V
K
L
I
N
I
W
K
--
R
F
--
G
----
D
----
V
T
A
V
K
D
L
S
L
E
I
K
D
G
E
F
L
V
L
L
G
P
S
G
C
G
K
T
T
T
L
R
M
I
A
G
L
E
E
P
T
R
G
Q
I
Y
I
E
--------
D
N
L
V
A
---
D
-------------
P
---
E
K
G
V
--
F
V
P
PK
E
R
D
---
V
A
M
V
F
Q
--------
S
Y
A
L
Y
P
H
M
T
V
Y
D
N
I
------
A
---
F
P
L
K
L
-
R
K
V
P
K
----------
Q
E
I
D
K
R
V
R
E
-
V
---
A
E
M
L
--------
G
L
-
T
E
L
L
-
N
----
R
K
P
R
E
L
S
G
G
Q
R
Q
R
V
A
L
G
R
A
I
I
R
R
P
K
V
F
L
M
D
E
P
L
S
N
L
D
A
K
L
R
V
K
M
R
A
E
L
K
K
L
Q
R
Q
L
G
V
T
T
I
Y
V
T
H
D
Q
V
E
A
-
M
-
T
-
M
----
G
D
R
I
A
V
M
N
K
G
E
L
Q
Q
V
G
T
P
D
E
V
----------------------------------------------------------------------------------------------------------------------------------------