@TOME V2.3
(Nov 2016)
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo0999: (2016-03-20 )
MLEKNYKFLLWIYIFWFLGSVLLVSLHIIPPELTAVQSLFLVFTGVFAAVFFIMQYGKWLGSAITLLIFVVSTCIEWMQLSYTDEYIGSTLGGSVYGIPITMGFIWVGMVAGTHIIAREITLKINIDWIRGGIYSFIAATMVMIFEVLIEPITMQSKQLYITQNGFTILQLSDFINWWLLGLILHLMIYFILSLTDSWERLKYPDLKSEIVIVYWIIIAFFVFLSFYLDLWTSIAIIIVSNIIFTACYFFSLEKETQTKKKSE
Atome Classification :
(14 SA)
----------------------------------------------------------------........-.-10...--.....--------20-----------...-......------30.-.-......40....----------------------....50...-----.....60.---------------......-.70.------.......80..-.......90....-....-100-.--.......-.-110.....-----..---120.......---130.-----------....--..140.--..----...-.150-..--.----....160.......170------........180------------...------...----.-.190---..-...---....200.--......210....-----.....---------220-..----...-...230.......240-.....--------...250.......260.---------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------------------------------------------MLEKN
Y
K
F
-
L
-
L
W
I
Y
I
--
F
W
F
L
G
--------
S
------------
V
L
L
-
V
S
LHII------P
P
E
-
L
-
T
A
V
Q
S
L
F
L
V
F
T
G
----------------------
V
F
A
A
V
F
F
I
M
-----
Q
Y
G
K
W
L
G
S
---------------
A
I
T
L
L
I
-
F
V
V
S
------
T
C
I
E
W
M
Q
L-S
Y
-
T
D
E
Y
I
G
S
TLGG
S
V
-
Y
G
I
P
-
I
---
T
--
M
G
F
I
W
V
G
-
M
-
V
AG
T
H
I
I
A
-----
R
E
---
I
T
L
K
I
N
I
D
W
I
---
R
G
G
I
-----------
Y
S
F
I
--
A
A
T
M
V
M
--
I
F
----
E
V
L
-IEPI-TM--Q----
S
K
Q
L
Y
I
TQN
G
F
T
I
L
Q
-
L
------
S
D
F
I
N
W
W
L
L
G
-------------
L
I
L
------
H
L
M
----
I
-
Y
F
-----
I
L
-SLT---D
S
W
E
RLKY--PDLKS
E
I
--
V
I
V
Y
-----
W
I
I
I
A
---------
F
F
--
V
F
----
L
S
F
-
Y
L
D
L
W
T
S
I
A
I
I
I
V
S
N
--
I
I
F
T
A
--------
C
Y
F
FSLEKETQTKKKSE---------------
10
Fugue
74.57
20%
-186
* C5 *
3B7F
21
?
A:
[16-393]
----------------------------------------------------------------
S
A
P
E
S
G
P
V
M
L
-
L
V
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K
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A
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A
--------
S
D
PARR
T
W
E
L
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P
V
F
L
G
H
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H
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Q
DPRE
P
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R
M
L
M
A
A
R
T
L
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P
T
V
F
R
S
DDGGG
N
W
T
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A
TRPPAFNKAPGR
V
V
D
H
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F
W
L
T
P
G
H
AS
E
P
G
T
W
Y
A
G
---------------
T
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G
L
-
F
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DHGA
S
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P
V
A
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N
D
-
H
P
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D
--
P
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S
G
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V
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-----
D
A
---
G
T
-----
D
W
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A
-----------
A
N
F
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--
P
D
P
N
V
---------
E
F
G
-
H
D
P
H
-
C
V
--
V
Q
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PA
A
P
D
I
L
Y
Q
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N
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C
G
I
Y
R
M
D
------
R
R
E
G
V
W
K
R
I
G
DAMPREVGDIG
F
P
I
V
V
------
H
Q
R
DPR
T
V
-
W
V
-----
F
P
M
D
G
S
---
D
V
W
P
R
V
S
---
P
G
G
K
P
A
V
--
Y
V
T
R
DAGE
S
W
Q
R
Q
D
R
GLPTDQAW
L
T
--
V
K
----
R
Q
A
M
T
A
D
A
H
A
P
V
G
V
Y
F
G
T
T
G
G
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I
W
A
S
ADEGEHWQ
C
I
A
S
H
L
P
H
I
Y
A
V
Q
S
A
R
P
---------------
12
Fugue
74.46
16%
-154
- C6 -
4QT4
-
PTH_STRPZ
A:
[1-189]
----------------------------------------------------------------------------
M
V
K
M
--
I
V
G
L
G
--------
N
----------------------------------------------------------------------------------
P
G
S
K
Y
E
K
T
---------------
K
H
N
I
G
F
-
M
A
I
D
------
N
I
V
K
N
L
D
V
-
T
F
-
T
D
D
K
N
F
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A
Q
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G
S
T
-
F
I
N
H
-
E
---
K
--
V
Y
F
V
K
P
T
-
T
F
M
N
N
S
G
I
A
V
-----
K
A
---
L
L
T
Y
Y
N
I
D
--------------------------
I
T
D
L
I
V
--
I
Y
----
D
D
L
------
D
M
--
E
----
V
S
K
L
R
L
R
S
K
G
-------------
S
A
G
G
H
N
G
I
K
S
-------------
I
I
A
------
H
I
G
------------------
T
---
Q
E
F
N
R
I
K
V
G
I
G
R
P
L
K
G
M
--
T
V
I
N
-----
H
V
M
G
Q
---------
F
---------------
N
T
E
D
N
I
A
I
S
L
T
L
D
--
R
V
V
N
A
--------
V
K
F
Y
L
Q
E
N
D
F
E
K
T
M
Q
K
F
NG-------------
17
Fugue
69.97
17%
-137
- C4 -
19HC
15
CYC9_DESDA
A:
[1-292]
---------------------------------------------------------------A
A
L
E
P
T
D
S
G
-
A
-
P
S
A
I
V
--
M
F
P
V
G
EKPNPKGA
A
------------
M
K
P
-
V
V
F
N
H
L
------
I
H
E
-
K
-
K
I
A
D
C
E
T
C
H
H
T
G
D---------------------
P
V
S
C
S
T
C
H
T
-----
V
E
G
K
A
E
G
D
---------------
Y
I
T
L
D
R
-
A
M
H
A
------
T
D
I
A
A
R
A
K
-
G
N
-
T
P
T
S
C
V
S
C
H
Q
S
E
T
-
K
E
R
R
-
E
---
C
--
A
G
C
H
A
I
T
-
T
-
P
K
D
D
E
A
W
C
-----
A
T
CHD
I
T
P
S
M
T
P
S
E
M
---
Q
K
G
I
-----------
A
G
T
L
L
P
G
D
N
E
A
L
--
A
A
----
E
T
V
-
L
A
E
A
-
T
V
--
A
----
P
V
S
P
M
L
A
P
Y
K
V
V
I
D
A
-
L
ADKYEP
S
D
F
T
H
R
R
H
L
T
-------------
S
L
M
E
S
I
K
DD
K
L
A
----
Q
-
A
F
H
DKPE
I
L
-
C
A
T
CHH
R
S
P
L
S
L
T
P
--
P
K
C
G
S
C
H
--
T
K
E
I
-----
D
A
A
D
P
---------
G
R
PN
L
M
----
A
A
Y
-
H
L
E
C
M
G
C
H
K
G
M
A
V
A
R
--
P
R
D
T
D
--------
C
--------
T
T
C
H
K
A
A
A
---------------
11
Fugue
61.96
14%
-150
* C6 *
4YMU
2
?
C:
[1-214]
-----------------------------------------------------------------
M
T
V
D
F
L
S
-
M
-
V
K
Y
T
P
--
L
F
I
S
G
--------
L
------------
I
M
T
-
L
K
L
T
F
L
------
A
V
T
-
I
-
G
V
L
M
G
L
F
I
A
L
M
K
----------------------
M
--------------------
S
---------------
S
I
K
P
I
K
-
L
V
A
S
------
S
Y
I
E
V
I
R
--------------------
G
T
P
-
L
---
L
--
V
Q
L
L
L
I
Y
-
N
-
G
L
M
Q
----------------
F
G
M
N
I
P
A
F
---
T
A
G
V
-----------
S
A
L
A
--
I
N
S
S
A
Y
--
V
A
----
E
I
I
-
R
A
G
I
-
Q
A
VD
P
----
G
Q
N
E
A
A
R
S
L
G
M
T
H
A
M
-
A
------
M
R
Y
V
------------------------------------------------
I
I
---
P
Q
A
I
K
N
I
L
--
P
A
L
G
N
E
F
--
I
V
M
L
-----
K
E
S
A
I
---------
V
S
--
V
I
GFAD
L
T
R
-
Q
A
D
I
I
Q
S
V
T
Y
R
Y
F
E
P
--
Y
I
I
I
A
--------
A
I
Y
F
V
M
T
L
T
F
S
K
L
L
S
L
F
ERRL-----------
16
Fugue
59.18
10%
-140
- C5 -
3B9W
2
?
A:
[8-369]
IN
E
A
R
L
V
A
Q
Y
N
Y
S
I
N
I
L
A
M
L
L
V
G
F
G
F
L
M
VFVRRY
G
F
S
A
T
T
G
T
Y
L
V
V
A
T
G
L
P
L
Y
I
L
L
R
A
N
GIFGH
A
L
T
P
H
S
V
D
-
A
-
V
I
Y
A
E
--
F
A
V
A
T
--------
G
------------
L
I
A
-
M
G
A
V
L
G
------
R
L
R
-
V
-
F
Q
Y
A
L
L
A
L
F
I
V
P
----------------------
V
Y
L
L
N
E
W
L
V
-----
L
D
N
A
S
G
L
T
EGFQDSAGSIAI
H
A
F
G
A
Y
F
G
L
-
G
V
S
I
------
A
L
T
T
A
A
Q
R
-
A
Q
-
P
I
E
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A
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D
R
F
S
M
-
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G
S
M
-
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------
L
W
L
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P
S
-
F
-
A
T
A
I
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E
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Q
M
---
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Q
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I
V
N
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A
---
L
C
G
A
-----------
T
L
A
T
--
Y
F
L
S
A
L
--
F
H
KGKA
S
I
V
-
D
M
A
N
-
A
A
--
L
----
A
G
G
V
A
I
G
S
V
C
N
I
V
G
P
-
V
------
G
A
F
V
I
G
L
L
G
G
-------------
A
I
S
------
V
V
G
----
F
-
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F
-----
I
Q
-
P
M
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---
E
S
K
A
K
T
I
D
--
T
C
G
V
H
N
L
HG
L
P
G
L
-----
L
G
G
F
S
---------
A
I
--
L
I
----
V
P
G
-
I
A
V
A
Q
L
T
G
I
G
I
T
L
A
L
--
A
L
I
G
G
--------
V
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A
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L
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G
T
T
K
Q
A
Y
EDSHEFIHLAGPEDE
15
Fugue
56.69
20%
-179
- C3 -
4PW1
1
?
A:
[16-252]
---------------------------------------------------------------N
L
L
Y
L
N
S
G
E
-
E
-
L
N
L
Y
P
---
W
N
L
Y
--------
T
----------------------------
G
Q
E
-
Q
-
E
L
F
E
E
E
I
V
S
F
A
A
----------------------
N
S
V
R
I
---
L
-----
G
G
G
S
W
T
D
E
---------------
E
L
Y
P
L
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F
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Y
S
G-----
Q
D
L
R
F
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A
L
-
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K
------
D
G
R
R
-
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---
L
D
P
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F
S
-
Y
-
V
N
Q
D
E
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E
A
T
A
D
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M
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Q
---
A
L
G
K
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Q
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E
---
K
F
L
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-----------
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P
L
P
--
K
T
D
N
A
F
Y
M
F
F
M
---
R
C
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M
L
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D
Q
M
R
K
--
E
----
Q
Y
S
D
Y
I
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D
N
L
Y
T
I
W
E
-
L
------
V
L
K
S
E
F
T
S
L
S
-------------
Y
D
N
------
H
I
Y
----
A
M
Y
-------------------------
S
N
D
G
G
T
S
M
-
V
L
I
Y
-----
S
P
I
E
E
---------
R
F
--
V
G
----
F
S
L
-
K
Y
------------------------------------------------------------
14
Fugue
50.21
15%
-118
- C2 -
2XQH
4
?
A:
[23-280]
----------------------------------------------SDAKASGEF
S
V
A
V
G
NG
A
R
A
T
E
K
A
S
T
A
-
V
G
S
W
A
A
A
--
D
G
K
Q
S
--------
T
------------
A
L
G
-
V
G
T
Y
A
Y
------
A
N
A
-
S
-
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A
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S
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A
F
V
D
N
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----------------------
A
-------------
T
Y
G
T
A
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N
---------------
R
A
K
V
D
K
-
D
A
T
E
------
G
T
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L
G
A
K
A
-
T
V
-
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N
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--
N
S
V
A
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G
A
--
N
S
V
T
-
T
---
R
--
D
N
E
V
Y
I
G
-
Y
-
K
T
G
T
E
--------------
S
D
K
T
Y
G
T
R
V
---
L
G
G
L
SDGTRNSDAAT
V
G
Q
L
--
N
R
K
V
G
G
--
V
Y
----
D
D
V
-
K
A
R
I
-
T
V
--
E
----
S
E
K
Q
K
K
Y
T
D
Q
K
T
S
E
V
-
N
------
E
K
V
E
A
R
T
T
V
G
-------------
V
---------------------------------
D
S
D
G
K
L
T
R
--
A
E
G
A
T
K
T
--
I
A
V
N
-----
D
G
L
V
A
---------
L
S
--
G
R
----
T
D
R
-
I
D
Y
A
V
G
A
I
D
G
R
V
T
R
N
--
T
Q
S
I
E
--------
K
N
S
K
A
I
A
A
N
T
R
T
--------------------
4
PsiBlast_PDB
37.70
34%
14
- C7 -
3NYA
1
ADRB2_HUMAN (first)
A:
[102-133]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
M
K
---------
M
W
--
T
F
----
G
N
F
-
W
C
E
F
W
T
S
I
D
V
L
C
V
T
A
--
S
I
W
T
L
--------
C
-------------------------------
2
PsiBlast_PDB
36.10
34%
12
- C7 -
3NY8
4
ENLYS_BPT4
A:
[102-133]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
M
K
---------
M
W
--
T
F
----
G
N
F
-
W
C
E
F
W
T
S
I
D
V
L
C
V
T
A
--
S
I
W
T
L
--------
C
-------------------------------
3
PsiBlast_PDB
35.64
34%
14
- C7 -
3NY9
2
ADRB2_HUMAN (first)
A:
[102-133]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
M
K
---------
M
W
--
T
F
----
G
N
F
-
W
C
E
F
W
T
S
I
D
V
L
C
V
T
A
--
S
I
W
T
L
--------
C
-------------------------------
1
PsiBlast_PDB
32.28
34%
11
- C7 -
3D4S
1
ENLYS_BPT4
A:
[102-133]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
L
M
K
---------
M
W
--
T
F
----
G
N
F
-
W
C
E
F
W
T
S
I
D
V
L
C
V
T
A
--
S
I
W
T
L
--------
C
-------------------------------
6
HHSearch
29.37
15%
611
* C7 *
2L8S
-
A:
[30-42]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
W
K
I
G
F
F
K
R
P
L
K
K
-----------------
5
HHSearch
19.93
21%
288
- C7 -
2RDD
-
YAJC_ECOLI
B:
[12-30]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
G
L
I
--------
F
Y
F
M
I
L
R
P
Q
Q
K
R
T
K
E
-----------------
8
HHSearch
3.01
13%
1046
- C1 -
3L32
-
PHOSP_RABVR
A:
[91-98]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
L
L
-
F
------
Q
S
Y
L
D
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------