@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1005: (2016-03-20 )
MEKIGFVGTGVMGSSMAGHLLEAGYEVLVYTRTKTKAEDLLDKGALWVETPGELANKVDILISMVGYPKDVEELYLGENGFLENLAVGTVAIDMTTSSPALAKKMAEFGREKGIGVLDAPVSGGDIGAKNGTLSIMVGGSEDVFLKVKPIFDILGSSVILQGDAGAGQHTKMVNQIAIASNMIGVTEAIIYAEAAGLNPSRVLDSISGGAAGSWSLANLIPRVLKDDFSPGFFIKHFIKDMGIAISEAKQMGLELPGLTLAEKMYQTLAEQGLSEEGTQALIKYYR
Atome Classification :
(22 SA)
---.........10........20........30........40...-.....50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.-......170.......180.......190.......200.......210.....--..220-------....-----...230.......240.......250.......260.......270.......280....---
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---MEKIGFVGTGVM
G
S
S
M
A
G
H
L
L
EAG
Y
E
V
L
V
Y
TRTK
T
K
A
E
D
L
L
DKG-
A
L
W
V
E
T
P
G
E
L
A
N
K
V
D
I
L
I
S
MVGYP
K
D
V
E
E
L
YLGENGFLENL
A
V
G
T
V
A
I
D
MTTS
S
P
A
L
A
K
K
M
A
E
F
G
REKGI
G
V
LDAPVSGGDIGAKN
G
T
L
S
I
M
VGGS
E
D
V
F
L
K
V
K
P
I
F
D
ILGS
S
V
I
L
QGD-AGA
G
Q
H
T
K
M
V
N
Q
I
A
I
A
S
N
M
I
G
V
T
E
A
I
I
Y
AEAAGL
N
P
S
R
V
L
D
S
ISGGAAGS
W
S
L
A
--
N
L
I
P
R
-------
V
L
K
D-----DFSP
G
F
F
I
K
H
F
I
K
D
MG
I
A
I
S
E
A
K
Q
MGLELP
G
L
T
L
A
E
K
M
Y
Q
T
L
A
EQGLS
E
E
G
T
Q
A
L
I
K
YYR---
63
HHSearch
96.79
41%
-105
- C1 -
3WS7
3
?
A:
[20-303]
---
H
M
R
V
G
F
I
G
L
G
I
M
G
G
P
M
A
T
H
L
L
K
A
G
F
L
A
A
V
Y
N
R
T
R
E
K
T
K
P
F
A
E
A
G
-
V
Y
V
A
E
S
P
A
D
L
A
K
R
V
D
V
V
I
V
M
V
S
D
A
P
D
V
E
Q
V
L
F
G
P
S
G
V
V
E
G
A
R
P
G
L
I
V
V
D
M
S
T
N
S
P
D
W
A
R
K
F
A
E
R
L
A
Q
Y
G
I
E
F
L
D
A
P
V
T
G
G
Q
K
G
A
I
E
G
T
L
T
I
M
V
G
G
K
E
E
L
F
H
R
L
L
P
I
F
K
A
M
G
R
D
I
V
Y
M
G
P
-
V
G
Y
G
Q
A
M
K
L
V
N
Q
V
V
V
A
L
N
T
V
A
M
V
E
G
L
K
L
A
K
A
L
G
L
D
M
D
K
V
A
E
V
L
T
---
A
R
S
G
A
I
E
--
L
Y
L
P
K
-------
L
L
K
G
-----
D
L
S
P
G
F
K
A
E
H
L
K
K
D
L
G
Y
V
L
E
E
A
R
K
R
G
V
K
L
P
G
A
E
L
A
Y
E
L
Y
R
K
M
V
E
D
G
A
G
S
L
G
I
H
A
L
G
F
Y
-----
59
HHSearch
95.45
38%
-105
- C1 -
1VPD
2
?
A:
[6-290]
----
M
K
V
G
F
I
G
L
G
I
M
G
K
P
M
S
K
N
L
L
K
A
G
Y
S
L
V
V
S
D
R
N
P
E
A
I
A
D
V
I
A
A
G
-
A
E
T
A
S
T
A
K
A
I
A
E
Q
C
D
V
I
I
T
M
L
P
N
S
P
H
V
K
E
V
A
L
G
E
N
G
I
I
E
G
A
K
P
G
T
V
L
I
D
M
S
S
I
A
P
L
A
S
R
E
I
S
D
A
L
K
A
K
G
V
E
M
L
D
A
P
V
S
G
G
E
P
K
A
I
D
G
T
L
S
V
M
V
G
G
D
K
A
I
F
D
K
Y
Y
D
L
M
K
A
M
A
G
S
V
V
H
T
G
D
-
I
G
A
G
N
V
T
K
L
A
N
Q
V
I
V
A
L
N
I
A
A
M
S
E
A
L
T
L
A
T
K
A
G
V
N
P
D
L
V
Y
Q
A
I
R
G
G
L
A
G
S
T
V
L
D
--
A
K
A
P
M
-------
V
M
D
R
-----
N
F
K
P
G
F
R
I
D
L
H
I
K
D
L
A
N
A
L
D
T
S
H
G
V
G
A
Q
L
P
L
T
A
A
V
M
E
M
M
Q
A
L
R
A
D
G
H
G
N
D
D
H
S
A
L
A
C
Y
Y
E
---
1
PsiBlast_PDB
95.16
41%
-107
- C1 -
3WS7
3
?
A:
[22-300]
-----
R
V
G
F
I
G
L
G
I
M
G
G
P
M
A
T
H
L
L
K
A
G
F
L
A
A
V
Y
N
R
T
R
E
K
T
K
P
F
A
E
A
G
-
V
Y
V
A
E
S
P
A
D
L
A
K
R
V
D
V
V
I
V
M
V
S
D
A
P
D
V
E
Q
V
L
F
G
P
S
G
V
V
E
G
A
R
P
G
L
I
V
V
D
M
S
T
N
S
P
D
W
A
R
K
F
A
E
R
L
A
Q
Y
G
I
E
F
L
D
A
P
V
T
G
G
Q
K
G
A
I
E
G
T
L
T
I
M
V
G
G
K
E
E
L
F
H
R
L
L
P
I
F
K
A
M
G
R
D
I
V
Y
M
G
P
-
V
G
Y
G
Q
A
M
K
L
V
N
Q
V
V
V
A
L
N
T
V
A
M
V
E
G
L
K
L
A
K
A
L
G
L
D
M
D
K
V
A
E
V
L
T
---
A
R
S
G
A
I
E
--
L
Y
L
P
K
-------
L
L
K
G
-----
D
L
S
P
G
F
K
A
E
H
L
K
K
D
L
G
Y
V
L
E
E
A
R
K
R
G
V
K
L
P
G
A
E
L
A
Y
E
L
Y
R
K
M
V
E
D
G
A
G
S
L
G
I
H
A
L
--------
5
PsiBlast_PDB
93.78
36%
-107
- C1 -
1VPD
2
?
A:
[7-290]
-----
K
V
G
F
I
G
L
G
I
M
G
K
P
M
S
K
N
L
L
K
A
G
Y
S
L
V
V
S
D
R
N
P
E
A
I
A
D
V
I
A
A
G
-
A
E
T
A
S
T
A
K
A
I
A
E
Q
C
D
V
I
I
T
M
L
P
N
S
P
H
V
K
E
V
A
L
G
E
N
G
I
I
E
G
A
K
P
G
T
V
L
I
D
M
S
S
I
A
P
L
A
S
R
E
I
S
D
A
L
K
A
K
G
V
E
M
L
D
A
P
V
S
G
G
E
P
K
A
I
D
G
T
L
S
V
M
V
G
G
D
K
A
I
F
D
K
Y
Y
D
L
M
K
A
M
A
G
S
V
V
H
T
G
D
-
I
G
A
G
N
V
T
K
L
A
N
Q
V
I
V
A
L
N
I
A
A
M
S
E
A
L
T
L
A
T
K
A
G
V
N
P
D
L
V
Y
Q
A
I
R
G
G
L
A
G
S
T
V
L
D
--
A
K
A
P
M
-------
V
M
D
R
-----
N
F
K
P
G
F
R
I
D
L
H
I
K
D
L
A
N
A
L
D
T
S
H
G
V
G
A
Q
L
P
L
T
A
A
V
M
E
M
M
Q
A
L
R
A
D
G
H
G
N
D
D
H
S
A
L
A
C
Y
Y
E
---
2
PsiBlast_PDB
93.55
40%
-105
- C1 -
3W6Z
1
?
A:
[22-300]
-----
R
V
G
F
I
G
L
G
I
M
G
G
P
M
A
T
H
L
L
K
A
G
F
L
A
A
V
Y
N
R
T
R
E
K
T
K
P
F
A
E
A
G
-
V
Y
V
A
E
S
P
A
D
L
A
K
R
V
D
V
V
I
V
M
V
S
D
A
P
D
V
E
Q
V
L
F
G
P
S
G
V
V
E
G
A
R
P
G
L
I
V
V
D
M
S
T
N
S
P
D
W
A
R
K
F
A
E
R
L
A
Q
Y
G
I
E
F
L
D
A
P
V
T
G
G
Q
K
G
A
I
E
G
T
L
T
I
M
V
G
G
K
E
E
L
F
H
R
L
L
P
I
F
K
A
M
G
R
D
I
V
Y
M
G
P
-
V
G
Y
G
Q
A
M
M
L
V
N
Q
V
V
V
A
L
N
T
V
A
M
V
E
G
L
K
L
A
K
A
L
G
L
D
M
D
K
V
A
E
V
L
T
R
G
A
A
R
S
G
A
I
E
--
L
Y
L
P
K
-------
L
L
K
G
-----
D
L
S
P
G
F
K
A
E
H
L
K
K
D
L
G
Y
V
L
E
E
A
R
K
R
G
V
K
L
P
G
A
E
L
A
Y
E
L
Y
R
K
M
V
E
D
G
A
G
S
L
G
I
H
A
L
--------
55
HHSearch
90.83
29%
-104
- C1 -
3PDU
3
?
A:
[1-286]
---
M
T
T
Y
G
F
L
G
L
G
I
M
G
G
P
M
A
A
N
L
V
R
A
G
F
D
V
T
V
W
N
R
N
P
A
K
C
A
P
L
V
A
L
G
-
A
R
Q
A
S
S
P
A
E
V
C
A
A
C
D
I
T
I
A
M
L
A
D
P
A
A
A
R
E
V
C
F
G
A
N
G
V
L
E
G
I
G
G
G
R
G
Y
I
D
M
S
T
V
D
D
E
T
S
T
A
I
G
A
A
V
T
A
R
G
G
R
F
L
E
A
P
V
S
G
T
K
K
P
A
E
D
G
T
L
I
I
L
A
A
G
D
Q
S
L
F
T
D
A
G
P
A
F
A
A
L
G
K
K
C
L
H
L
G
E
-
V
G
Q
G
A
R
M
K
L
V
V
N
M
I
M
G
Q
M
M
T
A
L
G
E
G
M
A
L
G
R
N
C
G
L
D
G
G
Q
L
L
E
V
L
D
A
G
A
M
A
N
P
M
F
K
--
G
K
G
Q
M
-------
L
L
S
G
-----
E
F
P
T
S
F
P
L
K
H
M
Q
K
D
L
R
L
A
V
E
L
G
D
R
L
G
Q
P
L
H
G
A
A
T
A
N
E
S
F
K
R
A
R
A
A
G
H
A
D
E
D
F
A
A
V
F
R
V
L
E
---
27
PsiBlast_CBE
90.16
31%
-107
- C1 -
3PEF
4
?
E:
[2-285]
----
Q
K
F
G
F
I
G
L
G
I
M
G
S
A
M
A
K
N
L
V
K
A
G
C
S
V
T
I
W
N
R
S
P
E
K
A
E
E
L
A
A
L
G
-
A
E
R
A
A
T
P
C
E
V
V
E
S
C
P
V
T
F
A
M
L
A
D
P
A
A
A
E
E
V
C
F
G
K
H
G
V
L
E
G
I
G
E
G
R
G
Y
V
D
M
S
T
V
D
P
A
T
S
Q
R
I
G
V
A
V
V
A
K
G
G
R
F
L
E
A
P
V
S
G
S
K
K
P
A
E
D
G
T
L
I
I
L
A
A
G
D
R
N
L
Y
D
E
A
M
P
G
F
E
K
M
G
K
K
I
I
H
L
G
D
-
V
G
K
G
A
E
M
K
L
V
V
N
M
V
M
G
G
M
M
A
C
F
C
E
G
L
A
L
G
E
K
A
G
L
A
T
D
A
I
L
D
V
I
G
A
G
A
M
A
N
P
M
F
A
--
L
K
G
G
L
-------
I
R
D
R
-----
N
F
A
P
A
F
P
L
K
H
M
Q
K
D
L
R
L
A
V
A
L
G
D
R
V
G
Q
P
L
V
A
S
A
A
A
N
E
L
F
K
G
A
R
A
A
G
F
G
D
E
D
F
S
A
I
F
K
T
Y
----
75
Fugue
89.71
29%
-107
- C1 -
3DOJ
1
GLYR1_ARATH
A:
[18-309]
GSH
M
M
E
V
G
F
L
G
L
G
I
M
G
K
A
M
S
M
N
L
L
K
N
G
F
K
V
T
V
W
N
R
T
L
S
K
C
D
E
L
V
E
H
G
-
A
S
V
C
E
S
P
A
E
V
I
K
K
C
K
Y
T
I
A
M
L
S
D
P
C
A
A
L
S
V
V
F
D
K
G
G
V
L
E
Q
I
C
E
G
K
G
Y
I
D
M
S
T
V
D
A
E
T
S
L
K
I
N
E
A
I
T
G
K
G
G
R
F
V
E
G
P
V
S
G
S
K
K
P
A
E
D
G
Q
L
I
I
L
A
A
G
D
K
A
L
F
E
E
S
I
P
A
F
D
V
L
G
K
R
S
F
Y
L
G
Q
-
V
G
N
G
A
K
M
K
L
I
V
N
M
I
M
G
S
M
M
N
A
F
S
E
G
L
V
L
A
D
K
S
G
L
S
S
D
T
L
L
D
I
L
D
L
G
A
M
T
N
P
M
F
K
--
G
K
G
P
S
-------
M
N
K
S
-----
S
Y
P
P
A
F
P
L
K
H
Q
Q
K
D
M
R
L
A
L
A
L
G
D
E
N
A
V
S
M
P
V
A
A
A
A
N
E
A
F
K
K
A
R
S
L
G
L
G
D
L
D
F
S
A
V
I
E
A
V
K
FSR
57
HHSearch
89.51
31%
-104
- C1 -
3PEF
6
?
A:
[1-286]
---
S
Q
K
F
G
F
I
G
L
G
I
M
G
S
A
M
A
K
N
L
V
K
A
G
C
S
V
T
I
W
N
R
S
P
E
K
A
E
E
L
A
A
L
G
-
A
E
R
A
A
T
P
C
E
V
V
E
S
C
P
V
T
F
A
M
L
A
D
P
A
A
A
E
E
V
C
F
G
K
H
G
V
L
E
G
I
G
E
G
R
G
Y
V
D
M
S
T
V
D
P
A
T
S
Q
R
I
G
V
A
V
V
A
K
G
G
R
F
L
E
A
P
V
S
G
S
K
K
P
A
E
D
G
T
L
I
I
L
A
A
G
D
R
N
L
Y
D
E
A
M
P
G
F
E
K
M
G
K
K
I
I
H
L
G
D
-
V
G
K
G
A
E
M
K
L
V
V
N
M
V
M
G
G
M
M
A
C
F
C
E
G
L
A
L
G
E
K
A
G
L
A
T
D
A
I
L
D
V
I
G
A
G
A
M
A
N
P
M
F
A
--
L
K
G
G
L
-------
I
R
D
R
-----
N
F
A
P
A
F
P
L
K
H
M
Q
K
D
L
R
L
A
V
A
L
G
D
R
V
G
Q
P
L
V
A
S
A
A
A
N
E
L
F
K
G
A
R
A
A
G
F
G
D
E
D
F
S
A
I
F
K
T
Y
E
---
26
PsiBlast_CBE
89.45
31%
-105
- C1 -
3PEF
1
?
F:
[2-285]
----
Q
K
F
G
F
I
G
L
G
I
M
G
S
A
M
A
K
N
L
V
K
A
G
C
S
V
T
I
W
N
R
S
P
E
K
A
E
E
L
A
A
L
G
-
A
E
R
A
A
T
P
C
E
V
V
E
S
C
P
V
T
F
A
M
L
A
D
P
A
A
A
E
E
V
C
F
G
K
H
G
V
L
E
G
I
G
E
G
R
G
Y
V
D
M
S
T
V
D
P
A
T
S
Q
R
I
G
V
A
V
V
A
K
G
G
R
F
L
E
A
P
V
S
G
S
K
K
P
A
E
D
G
T
L
I
I
L
A
A
G
D
R
N
L
Y
D
E
A
M
P
G
F
E
K
M
G
K
K
I
I
H
L
G
D
-
V
G
K
G
A
E
M
K
L
V
V
N
M
V
M
G
G
M
M
A
C
F
C
E
G
L
A
L
G
E
K
A
G
L
A
T
D
A
I
L
D
V
I
G
A
G
A
M
A
N
P
M
F
A
--
L
K
G
G
L
-------
I
R
D
R
-----
N
F
A
P
A
F
P
L
K
H
M
Q
K
D
L
R
L
A
V
A
L
G
D
R
V
G
Q
P
L
V
A
S
A
A
A
N
E
L
F
K
G
A
R
A
A
G
F
G
D
E
D
F
S
A
I
F
K
T
Y
----
7
PsiBlast_PDB
89.23
31%
-105
- C1 -
3PEF
6
?
A:
[2-285]
----
Q
K
F
G
F
I
G
L
G
I
M
G
S
A
M
A
K
N
L
V
K
A
G
C
S
V
T
I
W
N
R
S
P
E
K
A
E
E
L
A
A
L
G
-
A
E
R
A
A
T
P
C
E
V
V
E
S
C
P
V
T
F
A
M
L
A
D
P
A
A
A
E
E
V
C
F
G
K
H
G
V
L
E
G
I
G
E
G
R
G
Y
V
D
M
S
T
V
D
P
A
T
S
Q
R
I
G
V
A
V
V
A
K
G
G
R
F
L
E
A
P
V
S
G
S
K
K
P
A
E
D
G
T
L
I
I
L
A
A
G
D
R
N
L
Y
D
E
A
M
P
G
F
E
K
M
G
K
K
I
I
H
L
G
D
-
V
G
K
G
A
E
M
K
L
V
V
N
M
V
M
G
G
M
M
A
C
F
C
E
G
L
A
L
G
E
K
A
G
L
A
T
D
A
I
L
D
V
I
G
A
G
A
M
A
N
P
M
F
A
--
L
K
G
G
L
-------
I
R
D
R
-----
N
F
A
P
A
F
P
L
K
H
M
Q
K
D
L
R
L
A
V
A
L
G
D
R
V
G
Q
P
L
V
A
S
A
A
A
N
E
L
F
K
G
A
R
A
A
G
F
G
D
E
D
F
S
A
I
F
K
T
Y
----
30
PsiBlast_CBE
89.17
31%
-103
- C1 -
3PEF
2
?
B:
[2-285]
----
Q
K
F
G
F
I
G
L
G
I
M
G
S
A
M
A
K
N
L
V
K
A
G
C
S
V
T
I
W
N
R
S
P
E
K
A
E
E
L
A
A
L
G
-
A
E
R
A
A
T
P
C
E
V
V
E
S
C
P
V
T
F
A
M
L
A
D
P
A
A
A
E
E
V
C
F
G
K
H
G
V
L
E
G
I
G
E
G
R
G
Y
V
D
M
S
T
V
D
P
A
T
S
Q
R
I
G
V
A
V
V
A
K
G
G
R
F
L
E
A
P
V
S
G
S
K
K
P
A
E
D
G
T
L
I
I
L
A
A
G
D
R
N
L
Y
D
E
A
M
P
G
F
E
K
M
G
K
K
I
I
H
L
G
D
-
V
G
K
G
A
E
M
K
L
V
V
N
M
V
M
G
G
M
M
A
C
F
C
E
G
L
A
L
G
E
K
A
G
L
A
T
D
A
I
L
D
V
I
G
A
G
A
M
A
N
P
M
F
A
--
L
K
G
G
L
-------
I
R
D
R
-----
N
F
A
P
A
F
P
L
K
H
M
Q
K
D
L
R
L
A
V
A
L
G
D
R
V
G
Q
P
L
V
A
S
A
A
A
N
E
L
F
K
G
A
R
A
A
G
F
G
D
E
D
F
S
A
I
F
K
T
Y
----
24
PsiBlast_CBE
89.11
31%
-105
- C1 -
3PEF
4
?
H:
[2-285]
----
Q
K
F
G
F
I
G
L
G
I
M
G
S
A
M
A
K
N
L
V
K
A
G
C
S
V
T
I
W
N
R
S
P
E
K
A
E
E
L
A
A
L
G
-
A
E
R
A
A
T
P
C
E
V
V
E
S
C
P
V
T
F
A
M
L
A
D
P
A
A
A
E
E
V
C
F
G
K
H
G
V
L
E
G
I
G
E
G
R
G
Y
V
D
M
S
T
V
D
P
A
T
S
Q
R
I
G
V
A
V
V
A
K
G
G
R
F
L
E
A
P
V
S
G
S
K
K
P
A
E
D
G
T
L
I
I
L
A
A
G
D
R
N
L
Y
D
E
A
M
P
G
F
E
K
M
G
K
K
I
I
H
L
G
D
-
V
G
K
G
A
E
M
K
L
V
V
N
M
V
M
G
G
M
M
A
C
F
C
E
G
L
A
L
G
E
K
A
G
L
A
T
D
A
I
L
D
V
I
G
A
G
A
M
A
N
P
M
F
A
--
L
K
G
G
L
-------
I
R
D
R
-----
N
F
A
P
A
F
P
L
K
H
M
Q
K
D
L
R
L
A
V
A
L
G
D
R
V
G
Q
P
L
V
A
S
A
A
A
N
E
L
F
K
G
A
R
A
A
G
F
G
D
E
D
F
S
A
I
F
K
T
Y
----
62
HHSearch
89.08
29%
-107
- C1 -
3DOJ
1
GLYR1_ARATH
A:
[21-306]
---
M
M
E
V
G
F
L
G
L
G
I
M
G
K
A
M
S
M
N
L
L
K
N
G
F
K
V
T
V
W
N
R
T
L
S
K
C
D
E
L
V
E
H
G
-
A
S
V
C
E
S
P
A
E
V
I
K
K
C
K
Y
T
I
A
M
L
S
D
P
C
A
A
L
S
V
V
F
D
K
G
G
V
L
E
Q
I
C
E
G
K
G
Y
I
D
M
S
T
V
D
A
E
T
S
L
K
I
N
E
A
I
T
G
K
G
G
R
F
V
E
G
P
V
S
G
S
K
K
P
A
E
D
G
Q
L
I
I
L
A
A
G
D
K
A
L
F
E
E
S
I
P
A
F
D
V
L
G
K
R
S
F
Y
L
G
Q
-
V
G
N
G
A
K
M
K
L
I
V
N
M
I
M
G
S
M
M
N
A
F
S
E
G
L
V
L
A
D
K
S
G
L
S
S
D
T
L
L
D
I
L
D
L
G
A
M
T
N
P
M
F
K
--
G
K
G
P
S
-------
M
N
K
S
-----
S
Y
P
P
A
F
P
L
K
H
Q
Q
K
D
M
R
L
A
L
A
L
G
D
E
N
A
V
S
M
P
V
A
A
A
A
N
E
A
F
K
K
A
R
S
L
G
L
G
D
L
D
F
S
A
V
I
E
A
V
K
---
28
PsiBlast_CBE
88.86
31%
-103
- C1 -
3PEF
3
?
D:
[2-285]
----
Q
K
F
G
F
I
G
L
G
I
M
G
S
A
M
A
K
N
L
V
K
A
G
C
S
V
T
I
W
N
R
S
P
E
K
A
E
E
L
A
A
L
G
-
A
E
R
A
A
T
P
C
E
V
V
E
S
C
P
V
T
F
A
M
L
A
D
P
A
A
A
E
E
V
C
F
G
K
H
G
V
L
E
G
I
G
E
G
R
G
Y
V
D
M
S
T
V
D
P
A
T
S
Q
R
I
G
V
A
V
V
A
K
G
G
R
F
L
E
A
P
V
S
G
S
K
K
P
A
E
D
G
T
L
I
I
L
A
A
G
D
R
N
L
Y
D
E
A
M
P
G
F
E
K
M
G
K
K
I
I
H
L
G
D
-
V
G
K
G
A
E
M
K
L
V
V
N
M
V
M
G
G
M
M
A
C
F
C
E
G
L
A
L
G
E
K
A
G
L
A
T
D
A
I
L
D
V
I
G
A
G
A
M
A
N
P
M
F
A
--
L
K
G
G
L
-------
I
R
D
R
-----
N
F
A
P
A
F
P
L
K
H
M
Q
K
D
L
R
L
A
V
A
L
G
D
R
V
G
Q
P
L
V
A
S
A
A
A
N
E
L
F
K
G
A
R
A
A
G
F
G
D
E
D
F
S
A
I
F
K
T
Y
----
10
PsiBlast_PDB
88.65
29%
-107
- C1 -
3DOJ
1
GLYR1_ARATH
A:
[21-306]
---
M
M
E
V
G
F
L
G
L
G
I
M
G
K
A
M
S
M
N
L
L
K
N
G
F
K
V
T
V
W
N
R
T
L
S
K
C
D
E
L
V
E
H
G
-
A
S
V
C
E
S
P
A
E
V
I
K
K
C
K
Y
T
I
A
M
L
S
D
P
C
A
A
L
S
V
V
F
D
K
G
G
V
L
E
Q
I
C
E
G
K
G
Y
I
D
M
S
T
V
D
A
E
T
S
L
K
I
N
E
A
I
T
G
K
G
G
R
F
V
E
G
P
V
S
G
S
K
K
P
A
E
D
G
Q
L
I
I
L
A
A
G
D
K
A
L
F
E
E
S
I
P
A
F
D
V
L
G
K
R
S
F
Y
L
G
Q
-
V
G
N
G
A
K
M
K
L
I
V
N
M
I
M
G
S
M
M
N
A
F
S
E
G
L
V
L
A
D
K
S
G
L
S
S
D
T
L
L
D
I
L
D
L
G
A
M
T
N
P
M
F
K
--
G
K
G
P
S
-------
M
N
K
S
-----
S
Y
P
P
A
F
P
L
K
H
Q
Q
K
D
M
R
L
A
L
A
L
G
D
E
N
A
V
S
M
P
V
A
A
A
A
N
E
A
F
K
K
A
R
S
L
G
L
G
D
L
D
F
S
A
V
I
E
A
V
K
---
61
HHSearch
88.38
29%
-107
- C1 -
3G0O
2
?
A:
[7-293]
---
D
F
H
V
G
I
V
G
L
G
S
M
G
M
G
A
A
R
S
C
L
R
A
G
L
S
T
W
G
A
D
L
N
P
Q
A
C
A
N
L
L
A
E
G
A
C
G
A
A
A
S
A
R
E
F
A
G
V
V
D
A
L
V
I
L
V
V
N
A
A
Q
V
R
Q
V
L
F
--
D
G
V
A
H
L
M
K
P
G
S
A
V
M
V
S
S
T
I
S
S
A
D
A
Q
E
I
A
A
A
L
T
A
L
N
L
N
M
L
D
A
P
V
S
G
G
A
V
K
A
A
Q
G
E
M
T
V
M
A
S
G
S
E
A
A
F
T
R
L
K
P
V
L
D
A
V
A
S
N
V
Y
R
I
S
D
T
P
G
A
G
S
T
V
K
I
I
H
Q
L
L
A
G
V
H
I
A
A
A
A
E
A
M
A
L
A
A
R
A
G
I
P
L
D
V
M
Y
D
V
V
T
H
A
A
G
N
S
W
M
F
E
--
N
R
M
Q
H
-------
V
V
D
G
-----
D
Y
T
P
R
S
A
V
D
I
F
V
K
D
L
G
L
V
A
D
T
A
K
A
L
R
F
P
L
P
L
A
S
T
A
L
N
M
F
T
S
A
S
N
A
G
Y
G
K
E
D
D
S
A
V
I
K
I
F
----
11
PsiBlast_PDB
88.11
28%
-103
- C1 -
3PDU
3
?
A:
[1-283]
---
M
T
T
Y
G
F
L
G
L
G
I
M
G
G
P
M
A
A
N
L
V
R
A
G
F
D
V
T
V
W
N
R
N
P
A
K
C
A
P
L
V
A
L
G
-
A
R
Q
A
S
S
P
A
E
V
C
A
A
C
D
I
T
I
A
M
L
A
D
P
A
A
A
R
E
V
C
F
G
A
N
G
V
L
E
G
I
G
G
G
R
G
Y
I
D
M
S
T
V
D
D
E
T
S
T
A
I
G
A
A
V
T
A
R
G
G
R
F
L
E
A
P
V
S
G
T
K
K
P
A
E
D
G
T
L
I
I
L
A
A
G
D
Q
S
L
F
T
D
A
G
P
A
F
A
A
L
G
K
K
C
L
H
L
G
E
-
V
G
Q
G
A
R
M
K
L
V
V
N
M
I
M
G
Q
M
M
T
A
L
G
E
G
M
A
L
G
R
N
C
G
L
D
G
G
Q
L
L
E
V
L
D
A
G
A
M
A
N
P
M
F
K
--
G
K
G
Q
M
-------
L
L
S
G
-----
E
F
P
T
S
F
P
L
K
H
M
Q
K
D
L
R
L
A
V
E
L
G
D
R
L
G
Q
P
L
H
G
A
A
T
A
N
E
S
F
K
R
A
R
A
A
G
H
A
D
E
D
F
A
A
V
F
R
------
64
HHSearch
87.89
27%
-106
* C1 *
2UYY
2
GLYR1_HUMAN
A:
[30-315]
---
D
K
K
I
G
F
L
G
L
G
L
M
G
S
G
I
V
S
N
L
L
K
M
G
H
T
V
T
V
W
N
R
T
A
E
K
C
D
L
F
I
Q
E
G
-
A
R
L
G
R
T
P
A
E
V
V
S
T
C
D
I
T
F
A
C
V
S
D
P
K
A
A
K
D
L
V
L
G
P
S
G
V
L
Q
G
I
R
P
G
K
C
Y
V
D
M
S
T
V
D
A
D
T
V
T
E
L
A
Q
V
I
V
S
R
G
G
R
F
L
E
A
P
V
S
G
N
Q
Q
L
S
N
D
G
M
L
V
I
L
A
A
G
D
R
G
L
Y
E
D
C
S
S
C
F
Q
A
M
G
K
T
S
F
F
L
G
E
-
V
G
N
A
A
K
M
M
L
I
V
N
M
V
Q
G
S
F
M
A
T
I
A
E
G
L
T
L
A
Q
V
T
G
Q
S
Q
Q
T
L
L
D
I
L
N
Q
G
Q
L
A
S
I
F
L
D
--
Q
K
C
Q
N
-------
I
L
Q
G
-----
N
F
K
P
D
F
Y
L
K
Y
I
Q
K
D
L
R
L
A
I
A
L
G
D
A
V
N
H
P
T
P
M
A
A
A
A
N
E
V
Y
K
R
A
K
A
L
D
Q
S
D
N
D
M
S
A
V
Y
R
A
Y
I
---
29
PsiBlast_CBE
87.86
31%
-104
- C1 -
3PEF
2
?
C:
[2-285]
----
Q
K
F
G
F
I
G
L
G
I
M
G
S
A
M
A
K
N
L
V
K
A
G
C
S
V
T
I
W
N
R
S
P
E
K
A
E
E
L
A
A
L
G
-
A
E
R
A
A
T
P
C
E
V
V
E
S
C
P
V
T
F
A
M
L
A
D
P
A
A
A
E
E
V
C
F
G
K
H
G
V
L
E
G
I
G
E
G
R
G
Y
V
D
M
S
T
V
D
P
A
T
S
Q
R
I
G
V
A
V
V
A
K
G
G
R
F
L
E
A
P
V
S
G
S
K
K
P
A
E
D
G
T
L
I
I
L
A
A
G
D
R
N
L
Y
D
E
A
M
P
G
F
E
K
M
G
K
K
I
I
H
L
G
D
-
V
G
K
G
A
E
M
K
L
V
V
N
M
V
M
G
G
M
M
A
C
F
C
E
G
L
A
L
G
E
K
A
G
L
A
T
D
A
I
L
D
V
I
G
A
G
A
M
A
N
P
M
F
A
--
L
K
G
G
L
-------
I
R
D
R
-----
N
F
A
P
A
F
P
L
K
H
M
Q
K
D
L
R
L
A
V
A
L
G
D
R
V
G
Q
P
L
V
A
S
A
A
A
N
E
L
F
K
G
A
R
A
A
G
F
G
D
E
D
F
S
A
I
F
K
T
Y
----
56
HHSearch
86.82
34%
-105
- C1 -
3OBB
5
SERDH_PSEAE
A:
[3-295]
---
M
K
Q
I
A
F
I
G
L
G
H
M
G
A
P
M
A
T
N
L
L
K
A
G
Y
L
L
N
V
F
D
L
V
Q
S
A
V
D
G
L
V
A
A
G
-
A
S
A
A
R
S
A
R
D
A
V
Q
G
A
D
V
V
I
S
M
L
P
A
S
Q
H
V
E
G
L
Y
L
D
D
D
G
L
L
A
H
I
A
P
-
T
L
V
L
E
C
S
T
I
A
P
T
S
A
R
K
I
H
A
A
A
R
E
R
G
L
A
M
L
D
A
P
V
S
G
G
T
A
G
A
A
A
G
T
L
T
F
M
V
G
G
D
A
E
A
L
E
K
A
R
P
L
F
E
A
M
G
R
N
I
F
H
A
G
P
-
D
G
A
G
Q
V
A
K
V
C
N
N
Q
L
L
A
V
L
M
I
G
T
A
E
A
M
A
L
G
V
A
N
G
L
E
A
K
V
L
A
E
I
M
R
R
S
S
G
G
N
W
A
L
E
--
V
Y
N
P
W
PGVMENA
P
A
S
R
-----
D
Y
S
G
G
F
M
A
Q
L
M
A
K
D
L
G
L
A
Q
E
A
A
Q
A
S
A
S
S
T
P
M
G
S
L
A
L
S
L
Y
R
L
L
L
K
Q
G
Y
A
E
R
D
F
S
V
V
Q
K
L
F
D
---
17
PsiBlast_PDB
84.80
32%
-107
- C1 -
3OBB
5
SERDH_PSEAE
A:
[4-294]
----
K
Q
I
A
F
I
G
L
G
H
M
G
A
P
M
A
T
N
L
L
K
A
G
Y
L
L
N
V
F
D
L
V
Q
S
A
V
D
G
L
V
A
A
G
-
A
S
A
A
R
S
A
R
D
A
V
Q
G
A
D
V
V
I
S
M
L
P
A
S
Q
H
V
E
G
L
Y
L
D
D
D
G
L
L
A
H
I
A
P
-
T
L
V
L
E
C
S
T
I
A
P
T
S
A
R
K
I
H
A
A
A
R
E
R
G
L
A
M
L
D
A
P
V
S
G
G
T
A
G
A
A
A
G
T
L
T
F
M
V
G
G
D
A
E
A
L
E
K
A
R
P
L
F
E
A
M
G
R
N
I
F
H
A
G
P
-
D
G
A
G
Q
V
A
K
V
C
N
N
Q
L
L
A
V
L
M
I
G
T
A
E
A
M
A
L
G
V
A
N
G
L
E
A
K
V
L
A
E
I
M
R
R
S
S
G
G
N
W
A
L
E
VY
N
P
W
P
G
-------
V
M
E
N
APASR
D
Y
S
G
G
F
M
A
Q
L
M
A
K
D
L
G
L
A
Q
E
A
A
Q
A
S
A
S
S
T
P
M
G
S
L
A
L
S
L
Y
R
L
L
L
K
Q
G
Y
A
E
R
D
F
S
V
V
Q
K
L
F
----