@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1026: (2016-03-20 )
MTETRTEKKKKTTSTFTKVMKIASVALLGIIFFSITGLAAKYYITVQNTFSKINVPLESSNKTLSDLEKKKPFSVLLMGSDARAGEKNGRADTIILATANKQQNAVEMVSIPRDTKVDYGNGDIGKINASYSNGGPSGTVSAVEKLMPGVPVDYFISINMEGFKDLVDAVGGITVYNDIDLTEVNSKFVKGNITLNGTEALQYVRIRHEDPRGDFGRQDRQRDVIIGIANKVISSSGVSNFESIMKAVGDNFQTNMTLTDITSMAANYSSVLKNVDSQELKGEGEMIYSESYGFDLYYFAPDKTDLERIITMFKKSLDITE
Atome Classification :
(20 SA)
----------------------------------------------------------.........10-........20...---...-----------..-----30........40...---.....50...---...---..60........70........----80--.--.-...----..-.90........100.......-.110.....---.---.120--.-.-.-------..---....130.......140.------..-.--.-..150.......160.......170.......-180--------.-----.--------.----------.--..--.--------190.....----..200.......210......------------------.220........230------......-..240.......250..-.....260....-------.-....270-.-.--......280......-.--290.......-.300-......-...310....------...320
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
----------------------------------------------------------MTET
R
T
E
K
KKK-
T
T
S
T
F
T
K
V
M
K
I
A
S
---
V
A
L
-----------
L
G
-----
I
I
F
F
S
I
TGL
A
A
K
Y
Y
I
---
T
V
QNTF
S
K
I
N
---
V
PL---ESSN
K
T
L
S
D
L
EKKK
P
F
S
V
L
L
MG----SD--A--R-AGE----KN-GRA
D
T
I
I
L
A
TANK-QQN
A
V
E
M
-VSIPRDTKV---D---YG----N-G-D-------I
G
---
K
I
N
A
SYSNGGPSG
T
V
S
A
V
------
E
K
-L--M-PGVP
V
D
Y
F
I
S
I
N
M
E
G
F
K
D
L
V
D
AVGG
I
T
V
YNDI-
D
L
T--------E-----V--------N----------S--
K
F
--
V
--------
K
G
N
I
T
LN
G
----
T
E
A
L
Q
Y
V
R
I
RHEDPRGDFGRQ------------------DRQ-R
D
V
I
I
G
I
A
N
K
-------
V
ISSSG-V
S
N
F
E
S
I
M
K
A
VGDNFQT-N
M
T
L
T
D
--
I
T
S
M
-------
A
-
A
N
Y
S
S
-
V
-
L
-
K
--NV
D
S
Q
E
LKGEG
E
M
I
Y
-S--ES-YG
F
D
L
Y
Y
-FA---P
D
K
T
D
L
-
E
R
I
I
T
M
F
K
K
S------LDITE
12
HHSearch
99.08
95%
-92
- C4 -
3OWQ
-
?
A:
[70-320]
------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
P
F
S
V
L
L
M
G
----
S
D
---------------
N
-
G
R
A
D
T
I
I
L
A
T
A
N
K
-
Q
Q
N
A
V
E
M
-
V
S
I
P
R
D
T
K
V
---
D
---
Y
G
----
N
---
D
-------
I
G
---
K
I
N
A
S
Y
S
N
G
G
P
S
G
T
V
S
A
V
------
E
K
-
L
--
M
P
G
-
V
P
V
D
Y
F
I
S
I
N
M
E
G
F
K
D
L
V
D
A
V
G
G
I
T
V
Y
N
D
I
-
D
L
T
--------
E
-----
V
--------
N
----------
S
--
K
F
--
V
--------
K
G
N
I
T
L
N
G
----
T
D
A
L
Q
Y
V
R
I
R
H
E
D
P
R
G
D
F
G
R
Q
------------------
D
R
Q
-
R
D
V
I
I
G
I
A
N
K
-------
V
I
S
--------
E
S
I
M
K
A
V
G
D
N
F
Q
T
-
N
M
T
L
T
D
--
I
T
S
M
-------
A
-
T
N
Y
S
S
-
V
-
L
-
K
--
N
V
D
S
Q
E
L
K
G
E
G
E
M
I
Y
-
S
--
E
S
-
Y
G
F
D
L
Y
Y
-
F
A
---
P
D
E
T
D
L
-
E
R
V
I
N
M
F
K
K
S
------
L
D
I
T
-
1
PsiBlast_PDB
98.56
91%
-92
- C4 -
3OWQ
-
?
A:
[70-320]
------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
P
F
S
V
L
L
M
G
----
S
D
---------------
N
-
G
R
A
D
T
I
I
L
A
T
A
N
K
-
Q
Q
N
A
V
E
M
-
V
S
I
P
R
D
T
K
V
---
D
---
Y
G
----
N
---
D
-------
I
G
---
K
I
N
A
S
Y
S
N
G
G
P
S
G
T
V
S
A
V
------
E
K
-
L
--
M
-
P
G
V
P
V
D
Y
F
I
S
I
N
M
E
G
F
K
D
L
V
D
A
V
G
G
I
T
V
Y
N
D
I
-
D
L
T
--------
E
-----
V
--------
N
----------
S
--
K
F
--
V
--------
K
G
N
I
T
L
N
G
----
T
D
A
L
Q
Y
V
R
I
R
H
E
D
P
R
G
D
F
G
R
Q
------------------
D
R
Q
-
R
D
V
I
I
G
I
A
N
K
-------
V
I
S
--------
E
S
I
M
K
A
V
G
D
N
F
Q
T
-
N
M
T
L
T
D
--
I
T
S
M
-------
A
-
T
N
Y
S
S
-
V
-
L
-
K
--
N
V
D
S
Q
E
L
K
G
E
G
E
M
I
Y
-
S
--
E
S
-
Y
G
F
D
L
Y
Y
-
F
A
---
P
D
E
T
D
L
-
E
R
V
I
N
M
F
K
K
S
------
L
D
I
T
-
14
HHSearch
82.30
40%
-68
- C4 -
3QFI
-
?
A:
[54-306]
-------------------------------------------------------------------------------------------------------------------------------------------------------
A
N
I
D
A
Q
E
P
F
S
V
L
L
M
G
----
I
D
--
T
--
G
-
D
------------
D
T
T
M
V
V
T
I
N
P
-
K
E
N
K
S
T
M
-
I
S
L
D
R
D
I
L
T
---
D
---
I
V
----
G
-
N
D
T
-------
Q
D
---
K
L
N
H
A
Y
A
F
G
G
A
E
M
A
I
N
T
V
------
Q
E
-
L
--
L
-
D
-
I
P
I
H
H
Y
V
S
I
N
M
K
G
L
K
D
L
I
D
A
V
G
G
I
E
V
D
N
T
I
G
E
F
T
-----------------------
G
----------
I
--
T
V
--
P
--------
A
G
K
I
K
L
D
G
----
T
T
G
L
A
Y
A
R
M
R
H
E
D
P
E
G
D
V
G
R
Q
------------------
R
R
Q
-
R
E
V
V
E
K
I
V
R
K
-------
V
M
S
F
D
-----
Y
R
K
I
L
D
A
V
E
A
N
V
K
T
-
D
L
T
W
D
D
--
M
M
D
I
-------
Q
-
S
K
Y
L
S
-
A
-
F
-
K
--
T
I
D
S
E
Q
L
Q
G
Y
S
A
T
I
D
----------
D
I
Y
Y
-
Q
V
---
L
D
P
N
S
L
-
Y
K
T
Q
T
T
L
R
K
Q
------
L
G
L
K
-
2
PsiBlast_PDB
80.96
38%
-68
- C4 -
3QFI
-
?
A:
[53-307]
------------------------------------------------------------------------------------------------------------------------------------------------------
T
A
N
I
D
A
Q
E
P
F
S
V
L
L
M
G
----
I
D
--
T
GD---------------
D
T
T
M
V
V
T
I
N
P
-
K
E
N
K
S
T
M
-
I
S
L
D
R
D
I
L
T
---
D
I--
V
G
----
N
-
D
-
T
-------
Q
D
---
K
L
N
H
A
Y
A
F
G
G
A
E
M
A
I
N
T
V
------
Q
E
-
L
--
L
-
D
-
I
P
I
H
H
Y
V
S
I
N
M
K
G
L
K
D
L
I
D
A
V
G
G
I
E
V
D
N
T
I
G
E
F
T
-----------------------
G
----------
I
--
T
V
--
P
--------
A
G
K
I
K
L
D
G
----
T
T
G
L
A
Y
A
R
M
R
H
E
D
P
E
G
D
V
G
R
Q
------------------
R
R
Q
-
R
E
V
V
E
K
I
V
R
K
-------
V
M
S
F
D
-----
Y
R
K
I
L
D
A
V
E
A
N
V
K
T
-
D
L
T
W
D
D
--
M
M
D
I
-------
Q
-
S
K
Y
L
S
-
A
-
F
-
K
--
T
I
D
S
E
Q
L
Q
G
-----
Y
-
S
--
A
T
-
I
D
-
D
I
Y
Y
-
Q
V
---
L
D
P
N
S
L
-
Y
K
T
Q
T
T
L
R
K
Q
------
L
G
L
K
E
17
HHSearch
80.55
27%
-50
- C4 -
2XXP
3
?
A:
[125-383]
----------------------------------------------------------------------------------------------------------------------------------------------------------
S
K
N
Q
S
F
N
I
Y
V
S
G
----
I
D
--
T
--
Y
-
G
P
I
S---
S
V
-
S
R
S
D
V
N
I
L
M
T
V
N
R
-
D
T
K
K
I
L
L
-
T
T
T
P
R
D
A
Y
V
---
P
---
I
A
----
D
-
G
-
G
NNQ----
K
D
---
K
L
T
H
A
G
I
Y
-
G
V
D
S
S
I
H
T
L
------
E
N
-
L
--
Y
-
G
-
V
D
I
N
Y
Y
V
R
L
N
F
T
S
F
L
K
M
I
D
L
L
G
G
V
D
V
H
N
D
Q
-
E
F
S
--------
A
-----
L
HG------
K
----------
F
--
H
F
--
P
--------
V
G
N
V
H
L
D
S
----
E
Q
A
L
G
F
V
R
E
R
Y
S
L
A
D
G
D
R
D
R
G
------------------
R
N
Q
-
Q
K
V
I
V
A
I
L
Q
K
-------
L
T
S
T
E
A
-
L
K
N
Y
S
T
I
I
N
S
L
Q
D
S
I
Q
T
-
N
V
P
L
E
T
--
M
I
N
L
-------
V
-
N
A
Q
L
E
S
G
G
N
-
Y
--
K
V
N
S
Q
D
L
K
G
T
G
R
M
D
L
P
S
--
Y
A
M
P
D
S
N
L
Y
V
-
M
E
---
I
D
D
S
S
L
-
A
V
V
K
A
A
I
Q
D
V
------
M
E
---
9
PsiBlast_PDB
78.22
29%
-53
- C4 -
2XXQ
6
?
A:
[126-349]
-----------------------------------------------------------------------------------------------------------------------------------------------------------
K
N
Q
S
F
N
I
Y
V
S
G
----
I
D
--
T
--
Y
-
G
P
I
----
S
S
V
S
R
S
D
V
N
I
L
M
T
V
N
R
-
D
T
K
K
I
L
L
-
T
T
T
P
A
D
A
Y
V
PIA
D
---
G
G
----
N
-
N
-
Q
-------
K
D
---
K
L
----
T
H
A
G
I
Y
G
V
D
S
S
I
------
H
T
-
L
E
N
L
-
Y
G
V
D
I
N
Y
Y
V
R
L
N
F
T
S
F
L
K
M
I
D
L
L
G
G
V
D
V
H
N
D
Q
-
E
F
S
--------
A
-----
L
--------
H
----------
G
--
K
F
H
F
P
--------
V
G
N
V
H
L
D
S
----
E
Q
A
L
G
F
V
R
E
R
Y
S
L
A
D
G
D
R
D
R
G
------------------
R
N
Q
-
Q
K
V
I
V
A
I
L
Q
K
-------
L
T
S
T
E
A
-
L
K
N
Y
S
T
I
I
N
S
L
Q
D
S
I
Q
T
-
N
V
P
L
E
T
--
M
I
N
L
V
N
A
Q
L
E
S
G
-
G
N
Y
K
----------
V
N
S
Q
D
L
K
G
T
G
R
M
--------------------------------------------------
24
Fugue
77.98
22%
-53
- C4 -
3TEL
9
?
A:
[14-385]
--------------------S
E
Y
S
L
S
V
A
V
L
ADSEIENVTQLT
S
V
T
A
PTGTD
N
E
N
I
Q
K
L
L
A
D
I
K
S
S
Q
N
T
D
L
T
V
N
Q
S
S
S
Y
L
A
A
Y
K
---
S
L
I
-----------
A
G
ETK
A
I
V
L
N
S
V
F
E
N
I
I
E
L
E
Y
P
---
D
Y
A
S
K
I
K
K
I
Y
---
T
K
G
---
F
T
K
K
V
E
A
P
K
T
S
K
N
Q
S
F
N
I
Y
V
S
G
----
I
D
--
T
--
Y
G
P
I
S
----
S
V
-
S
R
S
D
V
N
I
L
M
T
V
N
R
-
D
T
K
K
I
L
L
-
T
T
T
P
A
D
A
Y
V
---
P
IAD
G
G
----
N
-
N
-
Q
-------
K
D
---
K
L
T
H
A
G
I
Y
G
-
V
D
S
S
I
H
T
L
------
E
N
-
L
--
Y
--
G
V
D
I
N
Y
Y
V
R
L
N
F
T
S
F
L
K
M
I
D
L
L
G
G
V
D
V
H
N
D
Q
-
E
F
S
--------
A
-----
L
--------
H
GK--------
F
--
H
F
--
P
--------
V
G
N
V
H
L
D
S
----
E
Q
A
L
G
F
V
R
E
R
Y
S
L
A
D
G
D
R
D
R
G
------------------
R
N
Q
-
Q
K
V
I
V
A
I
L
Q
K
-------
L
T
S
T
E
A
-
L
K
N
Y
S
T
I
I
N
S
L
Q
D
S
I
Q
T
-
N
V
P
L
E
T
--
M
I
N
L
-------
V
-
N
A
Q
L
E
-
S
-
G
-
G
N
Y
K
V
N
S
Q
D
L
K
G
T
G
R
M
D
L
-
P
SY
A
M
-
P
D
S
N
L
Y
V
-
M
E
---
I
D
D
S
S
L
-
A
V
V
K
A
A
I
Q
D
V
------
M
E
G
R
-
5
PsiBlast_PDB
77.88
29%
-55
- C4 -
3TEP
9
?
A:
[126-349]
-----------------------------------------------------------------------------------------------------------------------------------------------------------
K
N
Q
S
F
N
I
Y
V
S
G
----
I
D
--
T
--
Y
-
G
P
I
----
S
S
V
S
R
S
D
V
N
I
L
M
T
V
N
R
-
D
T
K
K
I
L
L
-
T
T
T
P
R
D
A
Y
V
PIA
D
---
G
G
----
N
-
N
-
Q
-------
K
D
---
K
L
----
T
H
A
G
I
Y
G
V
D
S
S
I
------
H
T
-
L
E
N
L
-
Y
G
V
D
I
N
Y
Y
V
R
L
N
F
T
S
F
L
K
M
I
D
L
L
G
G
V
D
V
H
N
D
Q
-
E
F
S
--------
A
-----
L
--------
H
----------
G
--
K
F
H
F
P
--------
V
G
N
V
H
L
D
S
----
E
Q
A
L
G
F
V
R
E
R
Y
S
L
A
D
G
D
R
D
R
G
------------------
R
N
Q
-
Q
K
V
I
V
A
I
L
Q
K
-------
L
T
S
T
E
A
-
L
K
N
Y
S
T
I
I
N
S
L
Q
D
S
I
Q
T
-
N
V
P
L
E
T
--
M
I
N
L
V
N
A
Q
L
E
S
G
-
G
N
Y
K
----------
V
N
S
Q
D
L
K
G
T
G
R
M
--------------------------------------------------
8
PsiBlast_PDB
77.54
29%
-56
- C4 -
3TEL
9
?
A:
[126-349]
-----------------------------------------------------------------------------------------------------------------------------------------------------------
K
N
Q
S
F
N
I
Y
V
S
G
----
I
D
--
T
--
Y
-
G
P
I
----
S
S
V
S
R
S
D
V
N
I
L
M
T
V
N
R
-
D
T
K
K
I
L
L
-
T
T
T
P
A
D
A
Y
V
PIA
D
---
G
G
----
N
-
N
-
Q
-------
K
D
---
K
L
----
T
H
A
G
I
Y
G
V
D
S
S
I
------
H
T
-
L
E
N
L
-
Y
G
V
D
I
N
Y
Y
V
R
L
N
F
T
S
F
L
K
M
I
D
L
L
G
G
V
D
V
H
N
D
Q
-
E
F
S
--------
A
-----
L
--------
H
----------
G
--
K
F
H
F
P
--------
V
G
N
V
H
L
D
S
----
E
Q
A
L
G
F
V
R
E
R
Y
S
L
A
D
G
D
R
D
R
G
------------------
R
N
Q
-
Q
K
V
I
V
A
I
L
Q
K
-------
L
T
S
T
E
A
-
L
K
N
Y
S
T
I
I
N
S
L
Q
D
S
I
Q
T
-
N
V
P
L
E
T
--
M
I
N
L
V
N
A
Q
L
E
S
G
-
G
N
Y
K
----------
V
N
S
Q
D
L
K
G
T
G
R
M
--------------------------------------------------
7
PsiBlast_PDB
77.33
29%
-53
- C4 -
2XXP
2
?
A:
[126-349]
-----------------------------------------------------------------------------------------------------------------------------------------------------------
K
N
Q
S
F
N
I
Y
V
S
G
----
I
D
--
T
--
Y
-
G
P
I
----
S
S
V
S
R
S
D
V
N
I
L
M
T
V
N
R
-
D
T
K
K
I
L
L
-
T
T
T
P
R
D
A
Y
V
PIA
D
---
G
G
----
N
-
N
-
Q
-------
K
D
---
K
L
----
T
H
A
G
I
Y
G
V
D
S
S
I
------
H
T
-
L
E
N
L
-
Y
G
V
D
I
N
Y
Y
V
R
L
N
F
T
S
F
L
K
M
I
D
L
L
G
G
V
D
V
H
N
D
Q
-
E
F
S
--------
A
-----
L
--------
H
----------
G
--
K
F
H
F
P
--------
V
G
N
V
H
L
D
S
----
E
Q
A
L
G
F
V
R
E
R
Y
S
L
A
D
G
D
R
D
R
G
------------------
R
N
Q
-
Q
K
V
I
V
A
I
L
Q
K
-------
L
T
S
T
E
A
-
L
K
N
Y
S
T
I
I
N
S
L
Q
D
S
I
Q
T
-
N
V
P
L
E
T
--
M
I
N
L
V
N
A
Q
L
E
S
G
-
G
N
Y
K
----------
V
N
S
Q
D
L
K
G
T
G
R
M
--------------------------------------------------
6
PsiBlast_PDB
76.97
29%
-54
- C4 -
3TFL
6
?
A:
[126-349]
-----------------------------------------------------------------------------------------------------------------------------------------------------------
K
N
Q
S
F
N
I
Y
V
S
G
----
I
D
--
T
--
Y
-
G
P
I
----
S
S
V
S
R
S
D
V
N
I
L
M
T
V
N
R
-
D
T
K
K
I
L
L
-
T
T
T
P
R
D
A
Y
V
PIA
D
---
G
G
----
N
-
N
-
Q
-------
K
D
---
K
L
----
T
H
A
G
I
Y
G
V
D
S
S
I
------
H
T
-
L
E
N
L
-
Y
G
V
D
I
N
Y
Y
V
R
L
N
F
T
S
F
L
K
M
I
D
L
L
G
G
V
D
V
H
N
D
Q
-
E
F
S
--------
A
-----
L
--------
H
----------
G
--
K
F
H
F
P
--------
V
G
N
V
H
L
D
S
----
E
Q
A
L
G
F
V
R
E
R
Y
S
L
A
D
G
D
R
D
R
G
------------------
R
N
Q
-
Q
K
V
I
V
A
I
L
Q
K
-------
L
T
S
T
E
A
-
L
K
N
Y
S
T
I
I
N
S
L
Q
D
S
I
Q
T
-
N
V
P
L
E
T
--
M
I
N
L
V
N
A
Q
L
E
S
G
-
G
N
Y
K
----------
V
N
S
Q
D
L
K
G
T
G
R
M
--------------------------------------------------
22
Fugue
74.13
31%
-60
* C4 *
3MEJ
1
YWTF_BACSU
A:
[7-279]
----------------------------------------------------------------------------------------------------------------------------------
H
V
S
L
A
---
R
G
E
---
Q
S
V
K
R
I
K
E
F
D
P
G
K
D
S
F
S
V
L
L
L
G
----
I
D
---------------
Q
-
A
R
S
D
A
N
V
L
V
T
F
N
R
-
K
E
K
T
A
-
K
M
L
S
I
P
R
D
A
Y
V
---
N
---
I
P
----
G
-
H
-
G
-------
Y
D
---
K
F
T
H
A
H
A
Y
G
G
V
D
L
T
V
K
T
V
------
E
E
M
L
-----
D
I
P
V
D
Y
V
V
E
S
N
F
T
A
F
E
D
V
V
N
E
L
N
G
V
K
V
T
V
K
S
-
D
K
V
--------
I
-----
Q
--------
Q
----------
I
--
K
K
--
D
T
K
GK
V
V
L
Q
K
G
T
H
T
L
D
G
----
E
E
A
L
A
Y
V
R
T
R
----
K
S
D
L
L
R
G
------------------
Q
R
Q
M
E
-
V
L
S
A
I
I
D
K
-------
S
K
S
L
D
T
M
G
Q
N
L
------------
K
M
N
L
S
L
K
D
--
A
I
G
L
-------
F
-
P
F
I
T
S
---
L
-
K
--
S
V
E
S
I
Q
L
T
G
Y
D
Y
E
P
A
----------
G
V
Y
Y
-
F
K
---
L
N
Q
Q
K
L
-
Q
E
V
K
K
E
L
Q
N
D
------
L
G
V
L
-
16
HHSearch
63.31
37%
19
- C4 -
3OKZ
-
?
A:
[51-321]
------------------------------------------------------------------------------------------------------------------------------------------------------
S
H
A
I
E
E
T
K
P
F
S
I
L
L
M
G
----
V
D
--
T
--
G
-
S
E
H
RKSK
W
S
-
G
N
S
D
S
M
I
L
V
T
I
N
P
-
K
T
N
K
T
T
M
-
T
S
L
E
R
D
V
L
I
---
K
---
L
S
----
G
-
P
-
K
NNGQTGV
E
A
---
K
L
N
A
A
Y
A
S
G
G
A
E
M
A
L
M
T
V
------
Q
D
-
L
--
L
-
D
-
I
N
V
D
Y
F
M
Q
I
N
M
Q
G
L
V
D
L
V
N
A
V
G
G
I
T
V
T
N
K
F
-
D
F
P
--------
I
-----
S
IAANEPEY
K
----------
A
--
V
V
--
E
--------
P
G
T
H
K
I
N
G
----
E
Q
A
L
V
Y
S
R
M
R
Y
D
D
P
E
G
D
Y
G
R
Q
------------------
K
R
Q
-
R
E
V
I
Q
K
V
L
K
K
-------
I
L
A
L
N
S
-
I
S
S
Y
K
K
I
L
S
A
V
S
N
N
M
Q
T
-
N
I
E
I
S
S
K
T
I
P
N
L
-------
L
-
A
Y
K
-
D
-
S
-
L
-
E
--
H
I
K
S
Y
Q
L
K
G
E
D
A
T
L
S
-----
D
----
G
G
S
Y
-
Q
I
---
L
T
K
K
H
L
-
L
A
V
Q
N
R
I
K
K
E
------
L
D
K
K
-
4
PsiBlast_PDB
60.86
37%
24
- C4 -
3OKZ
-
?
A:
[54-289]
---------------------------------------------------------------------------------------------------------------------------------------------------------
I
E
E
T
K
P
F
S
I
L
L
M
G
V
DTG
S
E
--
H
--
R
-
K
S
K
----
W
S
-
G
N
S
D
S
M
I
L
V
T
I
N
P
-
K
T
N
K
T
T
M
-
T
S
L
E
R
D
V
L
I
---
K
---
L
S
G
P
KN
N
-
G
-
Q
-------
T
G
VEA
K
L
N
A
A
Y
A
S
G
G
A
E
M
A
L
M
T
V
------
Q
D
-
L
--
L
--
D
I
N
V
D
Y
F
M
Q
I
N
M
Q
G
L
V
D
L
V
N
A
V
G
G
I
T
V
T
N
K
F
-
D
F
P
ISIAANEP
E
-----
Y
--------
K
----------
A
--
V
V
--
E
--------
P
G
T
H
K
I
N
G
----
E
Q
A
L
V
Y
S
R
M
R
Y
D
D
P
E
G
D
Y
G
R
Q
------------------
K
R
Q
-
R
E
V
I
Q
K
V
L
K
K
-------
I
L
A
L
N
S
-
I
S
S
Y
K
K
I
L
S
A
V
S
N
N
M
Q
T
-
N
I
E
I
S
S
K
T
I
P
N
L
-------
L
-
A
-
Y
K
D
-
S
-
L
-
E
--
H
I
K
S
Y
Q
L
K
G
E
-----------------------------------------------------
3
PsiBlast_PDB
58.92
36%
24
- C4 -
3NXH
-
YVHJ_BACSU
A:
[73-331]
-----------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
K
P
F
S
I
L
F
M
G
----
I
E
DY
A
--
T
-
K
G
Q
----
K
--
G
R
S
D
S
L
I
V
V
T
L
D
P
-
K
N
K
T
M
K
M
-
L
S
I
P
R
D
T
R
V
---
Q
---
L
A
------------------S
K
T
K
I
N
A
A
Y
S
K
G
G
K
D
E
T
V
E
T
V
------
E
N
-
F
--
L
-
Q
-
I
P
I
D
K
Y
V
T
V
D
F
D
G
F
K
D
V
I
N
E
V
G
G
I
D
V
D
V
P
---------------------------------------------------------
E
M
H
L
N
G
----
E
E
A
L
A
Y
A
---------
D
F
G
R
N
------------------
D
R
Q
-
K
Q
I
L
N
A
L
I
D
R
-------
M
S
---------
D
K
I
A
E
K
A
S
E
N
V
E
T
-
N
I
R
I
T
E
--
G
L
A
L
-------
Q
-
Q
I
Y
S
G
-
F
-
T
S
K
--
K
I
D
T
L
S
I
T
G
S
D
L
Y
L
G
-
P
--
N
N
-----
T
Y
Y
-
F
E
---
P
D
A
T
N
L
-
E
K
V
R
K
T
L
Q
E
H
------
L
D
Y
T
-
15
HHSearch
57.61
37%
14
- C4 -
3NXH
-
YVHJ_BACSU
A:
[74-331]
------------------------------------------------------------------------------------------------------------------------------------------------------------
K
K
P
F
S
I
L
F
M
G
----
I
E
--
D
--
Y
-
A
T
K
G---
Q
K
-
G
R
S
D
S
L
I
V
V
T
L
D
P
-
K
N
K
T
M
K
M
-
L
S
I
P
R
D
T
R
V
---
Q
---
L
A
--------
S
-------
K
T
---
K
I
N
A
A
Y
S
K
G
G
K
D
E
T
V
E
T
V
------
E
N
-
F
--
L
-
Q
-
I
P
I
D
K
Y
V
T
V
D
F
D
G
F
K
D
V
I
N
E
V
G
G
I
D
V
D
V
P
---------------------------------------------------------
E
M
H
L
N
G
----
E
E
A
L
A
Y
A
---------
D
F
G
R
N
------------------
D
R
Q
-
K
Q
I
L
N
A
L
I
D
R
-------
M
S
---------
D
K
I
A
E
K
A
S
E
N
V
E
T
-
N
I
R
I
T
E
--
G
L
A
L
-------
Q
-
Q
I
Y
S
G
F
T
-
S
-
K
--
K
I
D
T
L
S
I
T
G
S
D
L
Y
L
G
--------
P
N
N
T
Y
Y
-
F
E
---
P
D
A
T
N
L
-
E
K
V
R
K
T
L
Q
E
H
------
L
D
Y
T
-
10
PsiBlast_PDB
57.00
30%
18
- C4 -
3PE5
-
?
A:
[109-309]
---------------------------------------------------------------------------------------------------------------------------------------------------------------
L
N
I
M
L
F
G
----
S
D
--
E
--
R
-
P
G
E
----
T
G
Y
G
R
S
D
T
M
M
L
L
S
I
D
N
-
R
N
K
K
L
K
L
-
T
S
F
M
R
D
T
Y
V
---
N
---
V
P
----
E
-
W
-
G
-------
D
T
---
K
L
T
H
A
Y
S
Y
G
G
P
A
L
A
I
E
T
I
------
E
R
-
N
--
F
--
G
I
D
I
D
R
Y
A
V
V
Y
F
D
T
F
P
G
I
V
D
T
L
G
G
I
E
V
--
E
M
-
T
Q
T
--------
E
-----
A
--------
D
V
M
N
E
S
V
GPEF
A
--
N
F
--
T
--------
E
G
K
N
T
L
N
G
----
A
T
A
L
V
Y
V
R
I
R
Y
-
G
V
G
D
D
F
G
R
T
------------------
Q
R
Q
-
R
D
F
M
L
Q
V
L
N
K
-------
V
K
G
T
R
D
-
V
G
T
L
L
T
L
L
T
K
I
L
P
G
V
T
T
-
N
I
S
V
N
E
--
M
A
G
L
-------
A
-
G
---------------------------------------------------------------------------
13
HHSearch
56.09
27%
42
- C4 -
3PE5
-
?
A:
[104-361]
----------------------------------------------------------------------------------------------------------------------------------------------------------
K
D
P
M
V
L
N
I
M
L
F
G
----
S
D
--
E
--
R
-
P
G
E
T---
G
Y
-
G
R
S
D
T
M
M
L
L
S
I
D
N
-
R
N
K
K
L
K
L
-
T
S
F
M
R
D
T
Y
V
---
N
---
V
P
----
E
-
W
-
G
-------
D
T
---
K
L
T
H
A
Y
S
Y
G
G
P
A
L
A
I
E
T
I
------
E
R
-
N
--
F
-
G
-
I
D
I
D
R
Y
A
V
V
Y
F
D
T
F
P
G
I
V
D
T
L
G
G
I
E
V
E
M
T
Q
-
T
E
A
--------
D
V
M
N
E
S
V
GPE-----
F
----------
A
--
N
F
--
T
--------
E
G
K
N
T
L
N
G
----
A
T
A
L
V
Y
V
R
I
R
Y
G
V
-
G
D
D
F
G
R
T
------------------
Q
R
Q
-
R
D
F
M
L
Q
V
L
N
K
-------
V
K
G
T
R
D
-
V
G
T
L
L
T
L
L
T
K
I
L
P
G
V
T
T
-
N
I
S
V
N
E
--
M
A
G
L
-------
A
-
G
G
A
I
S
S
Y
M
D
-
Y
--
P
M
Y
Q
F
R
L
P
E
D
G
A
F
S
A
-
V
--
D
---
V
D
A
G
N
V
L
A
I
---
D
D
W
D
A
A
R
E
H
L
Q
R
F
I
Y
E
D
-----------
29
Fugue
48.02
16%
-37
- C3 -
2IUT
3
FTSK_PSEAE
A:
[70-477]
LPPLSLLDPAEVKQKSYS
P
E
S
L
E
A
M
S
R
L
L
E
I
K
L
K
E
F
G
V
E
V
S
V
D
S
V
H
P
G
PV
I
T
R
F
E
I
Q
P
A
A
G
V
K
V
S
R
I
S
N
-
L
A
K
D
L
A
R
S
L
A
V
I
S
---
V
R
V
V
EVIPGKT
T
V
G
I
E
-----
I
P
N
E
D
R
Q
M
V
R
F
S
E
V
L
S
S
P
E
Y
D
E
H
K
S
T
V
P
---
L
A
L
GHD
I
G
G
R
P
I
I
T
D
L
A
K
M
P
H
--
L
L
V
A
G
----
T
T
-----
G
-
S
G
-----
K
S
-
V
G
V
N
A
M
L
L
S
I
L
F
K
S
T
P
S
E
A
R
L
-
I
M
I
-----------------------
D
-------
P
K
---
M
L
E
L
S
I
Y
E
G
I
P
H
L
L
C
P
V
V
------
T
D
-
M
--
K
-
E
A
A
N
A
L
R
W
S
V
A
E
M
E
R
R
Y
R
L
M
A
A
M
G
V
R
-------
N
L
A
--------
G
-----
F
--------
N
----------
R
--
K
V
--
K
--------
D
A
E
E
A
G
T
P
----
L
T
D
P
L
F
R
R
E
S
P
D
D
E
P
P
Q
L
S
T
L
P
T
I
V
V
V
V
DEF
A
D
M
M
M
I
V
G
K
K
V
-
E
E
L
I
A
R
I
A
Q
K
ARAAG
I
H
L
I
L
A
T
Q
-
R
P
S
V
D
V
I
T
G
L
I
K
A
N
I
P
T
-
R
I
A
F
Q
----
V
S
S
-------
K
-
I
D
S
R
T
-
I
-
L
-
D
--
Q
G
G
A
E
Q
L
L
G
H
G
D
M
L
Y
-
L
--
P
P
-
G
T
G
L
P
I
R
-
V
H
G
A
F
V
S
D
D
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-
H
R
V
V
E
A
W
K
L
R
G
A
P
D
Y
I
E
D
I
L
A
25
Fugue
45.98
13%
-22
* C2 *
2E7J
3
SPSS1_ARCFU
A:
[8-371]
-------------------------------------------------DFINIDPLQ
T
G
G
K
L
T
E
E
A
R
Q
-
A
L
L
E
W
P
P
I
H
D
F
I
H
N
Q
L
P
K
F
-----------
L
G
-----
C
D
V
A
R
V
T
N
G
A
R
E
A
K
F
---
A
V
M
H
S
L
A
K
K
D
A
W
V
V
M
D
---
E
N
C
H
Y
S
S
Y
V
A
A
E
R
A
G
L
N
I
A
L
V
P
----
K
T
--
D
--
Y
-
P
D
Y
----
A
I
-
T
P
E
N
F
A
Q
T
I
E
E
T
K
-
K
R
G
E
V
V
L
-
A
L
I
T
Y
-
P
D
G
---
N
---
Y
G
----
N
L
P
-
D
-------
V
K
---
K
I
A
K
V
C
S
E
Y
D
V
P
L
L
V
N
G
A
YAIGR
M
P
V
-
S
--
L
-
K
E
I
G
A
D
-
F
I
V
G
S
G
H
K
S
M
A
A
S
G
P
I
G
V
M
G
M
K
E
E
W
-
A
E
I
--------
V
-----
L
--------
R
----------
R
SE
K
Y
--
K
--------
N
K
E
V
E
L
L
G
CTAR
G
A
T
I
I
T
L
M
A
S
F
P
H
V
R
E
R
I
K
R
W
------------------
D
E
E
-
V
E
K
A
R
R
F
A
A
E
-------
M
E
K
L
-
G
-
I
K
Q
L
G
D
N
P
H
N
H
D
L
M
F
F
H
-
A
E
V
L
Y
E
--
I
S
K
K
-------
A
K
G
G
R
F
F
-
L
-
Y
-
R
--
E
L
K
S
R
K
I
H
G
I
K
P
----
G
--
L
T
-
R
Y
F
K
L
S
T
-
Y
G
---
L
S
D
E
E
V
-
D
Y
V
L
N
A
F
K
E
I
------
I
E
K
Y
S