@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1084: (2016-03-21 )
MSILVTGANGQLGTELVQLLKEHNLTVTEWDKDSVDIVDKAAVKKAMLDLKPEWIIHCAAFTNVEAAEDELKNVNWEVNVDGTENISEAAEIVGAKLVYISTDYVFDGTKKEAYLPDDKTNPLNQYGIAKLAGEKVALEKNSQTYVIRTSWVFGKYGNNFVYSMLKLAETHKELKVVNDQLGRPTYTYDLADFIRFVIEKNPAYGIYQFSNSGTATWFEFATEILKDKDVTVNPCTSDEFPQKAERPKTSIMSLEKVEKLGFNIPTWQDALVRFKK
Atome Classification :
(20 SA)
---.........10........20.-..-------.....30------.....--....40........50........60-.........70........80........90........100.......110.......120.......130.......140.....-..150..---.....160...-....-170.......180.......190.----.....-.200-....----.....210.......220..--.---..-.-.-230----..--......240.......250.......-260.-..-..-----...270....----------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---
M
S
I
L
V
TGANGQ
L
G
T
E
L
V
Q
L
L
K
E-HN-------
L
T
V
TEW-------DKD
S
V
--
D
I
V
D
K
A
A
V
K
K
A
M
L
DLKP
E
W
I
I
H
C
A
A
--FTNV
E
A
A
E
D
E
L
KNV
N
W
E
V
NVDGTE
N
I
S
E
A
A
E
IVG
A
K
L
V
Y
I
S
T
D
Y
V
FDGTKKEAYLPDDKTN
P
L
N
QY
G
I
A
K
LAG
E
K
V
A
LEKNS
Q
T
Y
V
I
-
R
T
S
W
V
FG---KYG
N
N
F
V
Y
S
M
L
-
K
L
A
E
-
T
H
K
E
L
K
V
V
N
DQLGR
P
T
Y
T
Y
D
L
A
D
F
----
I
R
F
V
I
-EK---NPA
Y
----
G
I
Y
Q
FSNSG
T
A
T
W
F
E
F
A
T
E
I
--L---KD-K-D-VT-----VN--PCTSDEFP
Q
K
AERP
K
T
S
I
M
S
L
E
K
V
E
K
-L-GF-NI-P
T
-----
W
Q
D
A
L
V
RFKK----------
33
HHSearch
94.93
43%
-80
- C1 -
1VL0
2
?
A:
[13-287]
---
M
K
I
L
I
T
G
A
N
G
Q
L
G
R
E
I
Q
K
Q
L
K
G
-
K
N
-------
V
E
V
I
P
T
-------
D
V
Q
D
L
--
D
I
T
N
V
L
A
V
N
K
F
F
N
E
K
K
P
N
V
V
I
N
C
A
A
--
H
T
A
V
D
K
C
E
E
Q
-
Y
D
L
A
Y
K
I
N
A
I
G
P
K
N
L
A
A
A
A
Y
S
V
G
A
E
I
V
Q
I
S
T
D
Y
V
F
D
G
E
A
K
E
P
I
T
E
F
D
E
V
N
P
Q
S
A
Y
G
K
T
K
L
E
G
E
N
F
V
K
A
L
N
P
K
Y
Y
I
V
-
R
T
A
W
L
Y
G
---
D
G
-
N
N
F
V
K
T
M
I
-
N
L
G
K
-
T
H
D
E
L
K
V
V
H
D
Q
V
G
T
P
T
S
T
V
D
L
A
R
V
----
V
L
K
V
I
-
D
E
----
K
N
Y
----
G
T
F
H
C
T
C
K
G
I
C
S
W
Y
D
F
A
V
E
I
--
F
---
R
L
T
G
I
D
-
V
K
-----
V
T
--
P
C
T
T
E
E
F
P
R
P
A
K
R
P
K
Y
S
V
L
R
N
Y
M
L
E
L
-
T
T
G
D
-
I
T
-
R
E
-----
W
K
E
S
L
K
E
Y
I
-----------
22
PsiBlast_CBE
93.53
41%
-81
- C1 -
3SC6
5
?
E:
[8-280]
-----
V
I
I
T
G
A
N
G
Q
L
G
K
Q
L
Q
E
E
L
N
P
-
E
E
-------
Y
D
I
Y
P
F
-------
D
K
K
L
L
--
D
I
T
N
I
S
Q
V
Q
Q
V
V
Q
E
I
R
P
H
I
I
I
H
C
A
A
--
Y
T
K
V
D
Q
A
E
K
E
-
R
D
L
A
Y
V
I
N
A
I
G
A
R
N
V
A
V
A
S
Q
L
V
G
A
K
L
V
Y
I
S
T
D
Y
V
F
Q
G
D
R
P
E
G
Y
D
E
F
H
N
P
A
P
I
N
I
Y
G
A
S
K
Y
A
G
E
Q
F
V
K
E
L
H
N
K
Y
F
I
V
-
R
T
S
W
L
Y
G
---
K
Y
G
N
N
F
V
K
T
M
I
-
R
L
G
K
-
E
R
E
E
I
S
V
V
A
D
Q
I
G
S
P
T
Y
V
A
D
L
N
V
M
----
I
N
K
L
I
-
H
T
---
S
-
L
Y
----
G
T
Y
H
V
S
N
T
G
S
C
S
W
F
E
F
A
K
K
I
--
F
---
S
Y
-
A
-
N
-
M
K
-----
V
N
VL
P
V
S
T
E
E
F
---
A
A
R
P
K
Y
S
I
F
Q
H
N
M
L
R
L
-
N
-
G
F
L
Q
M
-
P
S
-----
W
E
E
G
L
E
R
F
------------
25
PsiBlast_CBE
92.75
41%
-84
- C1 -
3SC6
5
?
B:
[8-280]
-----
V
I
I
T
G
A
N
G
Q
L
G
K
Q
L
Q
E
E
L
N
P
-
E
E
-------
Y
D
I
Y
P
F
-------
D
K
K
L
L
--
D
I
T
N
I
S
Q
V
Q
Q
V
V
Q
E
I
R
P
H
I
I
I
H
C
A
A
--
Y
T
K
V
D
Q
A
E
K
E
-
R
D
L
A
Y
V
I
N
A
I
G
A
R
N
V
A
V
A
S
Q
L
V
G
A
K
L
V
Y
I
S
T
D
Y
V
F
Q
G
D
R
P
E
G
Y
D
E
F
H
N
P
A
P
I
N
I
Y
G
A
S
K
Y
A
G
E
Q
F
V
K
E
L
H
N
K
Y
F
I
V
-
R
T
S
W
L
Y
G
---
K
Y
G
N
N
F
V
K
T
M
I
-
R
L
G
K
-
E
R
E
E
I
S
V
V
A
D
Q
I
G
S
P
T
Y
V
A
D
L
N
V
M
----
I
N
K
L
I
-
H
T
---
S
-
L
Y
----
G
T
Y
H
V
S
N
T
G
S
C
S
W
F
E
F
A
K
K
I
--
F
---
S
Y
-
A
-
N
-
M
K
-----
V
N
V
L
P
V
S
T
----
A
A
A
A
R
P
K
Y
S
I
F
Q
H
N
M
L
R
L
-
N
-
G
F
L
Q
M
-
P
S
-----
W
E
E
G
L
E
R
F
------------
24
PsiBlast_CBE
90.75
41%
-80
- C1 -
3SC6
3
?
C:
[8-280]
-----
V
I
I
T
G
A
N
G
Q
L
G
K
Q
L
Q
E
E
L
N
P
-
E
E
-------
Y
D
I
Y
P
F
-------
D
K
K
L
L
--
D
I
T
N
I
S
Q
V
Q
Q
V
V
Q
E
I
R
P
H
I
I
I
H
C
A
A
--
Y
T
K
V
D
Q
A
E
K
E
-
R
D
L
A
Y
V
I
N
A
I
G
A
R
N
V
A
V
A
S
Q
L
V
G
A
K
L
V
Y
I
S
T
D
Y
V
F
Q
G
D
R
P
E
G
Y
D
E
F
H
N
P
A
P
I
N
I
Y
G
A
S
K
Y
A
G
E
Q
F
V
K
E
L
H
N
K
Y
F
I
V
-
R
T
S
W
L
Y
G
---
K
Y
G
N
N
F
V
K
T
M
I
-
R
L
G
K
-
E
R
E
E
I
S
V
V
A
D
Q
I
G
S
P
T
Y
V
A
D
L
N
V
M
----
I
N
K
L
I
-
H
T
---
S
-
L
Y
----
G
T
Y
H
V
S
N
T
G
S
C
S
W
F
E
F
A
K
K
I
--
F
---
S
Y
-
A
-
N
-
M
K
-----
V
N
V
L
P
V
S
T
E
E
F
G
A
A
A
A
R
P
K
Y
S
I
F
Q
H
N
M
L
R
L
-
N
-
G
F
L
Q
M
-
P
S
-----
W
E
E
G
L
E
R
F
------------
1
PsiBlast_PDB
90.22
41%
-78
- C1 -
3SC6
3
?
A:
[8-280]
-----
V
I
I
T
G
A
N
G
Q
L
G
K
Q
L
Q
E
E
L
N
P
-
E
E
-------
Y
D
I
Y
P
F
-------
D
K
K
L
L
--
D
I
T
N
I
S
Q
V
Q
Q
V
V
Q
E
I
R
P
H
I
I
I
H
C
A
A
--
Y
T
K
V
D
Q
A
E
K
E
-
R
D
L
A
Y
V
I
N
A
I
G
A
R
N
V
A
V
A
S
Q
L
V
G
A
K
L
V
Y
I
S
T
D
Y
V
F
Q
G
D
R
P
E
G
Y
D
E
F
H
N
P
A
P
I
N
I
Y
G
A
S
K
Y
A
G
E
Q
F
V
K
E
L
H
N
K
Y
F
I
V
-
R
T
S
W
L
Y
G
---
K
Y
G
N
N
F
V
K
T
M
I
-
R
L
G
K
-
E
R
E
E
I
S
V
V
A
D
Q
I
G
S
P
T
Y
V
A
D
L
N
V
M
----
I
N
K
L
I
-
H
T
---
S
-
L
Y
----
G
T
Y
H
V
S
N
T
G
S
C
S
W
F
E
F
A
K
K
I
--
F
---
S
Y
-
A
-
N
-
M
K
-----
V
N
V
L
P
V
S
T
E
E
F
G
A
A
A
A
R
P
K
Y
S
I
F
Q
H
N
M
L
R
L
-
N
-
G
F
L
Q
M
-
P
S
-----
W
E
E
G
L
E
R
F
------------
23
PsiBlast_CBE
88.96
41%
-76
- C1 -
3SC6
3
?
D:
[8-280]
-----
V
I
I
T
G
A
N
G
Q
L
G
K
Q
L
Q
E
E
L
N
P
-
E
E
-------
Y
D
I
Y
P
F
-------
D
K
K
L
L
--
D
I
T
N
I
S
Q
V
Q
Q
V
V
Q
E
I
R
P
H
I
I
I
H
C
A
A
--
Y
T
K
V
D
Q
A
E
K
E
-
R
D
L
A
Y
V
I
N
A
I
G
A
R
N
V
A
V
A
S
Q
L
V
G
A
K
L
V
Y
I
S
T
D
Y
V
F
Q
G
D
R
P
E
G
Y
D
E
F
H
N
P
A
P
I
N
I
Y
G
A
S
K
Y
A
G
E
Q
F
V
K
E
L
H
N
K
Y
F
I
V
-
R
T
S
W
L
Y
G
---
K
Y
G
N
N
F
V
K
T
M
I
-
R
L
G
K
-
E
R
E
E
I
S
V
V
A
D
Q
I
G
S
P
T
Y
V
A
D
L
N
V
M
----
I
N
K
L
I
-
H
T
---
S
-
L
Y
----
G
T
Y
H
V
S
N
T
G
S
C
S
W
F
E
F
A
K
K
I
--
F
---
S
Y
-
A
-
N
-
M
K
-----
V
N
VL
P
V
S
T
E
E
F
G
A
A
A
A
R
P
K
Y
S
I
F
Q
H
N
M
L
R
L
-
N
-
G
F
L
Q
M
-
P
S
-----
W
E
E
G
L
E
R
F
------------
32
HHSearch
86.96
42%
-76
- C1 -
3SC6
3
?
A:
[6-282]
---
E
R
V
I
I
T
G
A
N
G
Q
L
G
K
Q
L
Q
E
E
L
N
P
-
E
E
-------
Y
D
I
Y
P
F
-------
D
K
K
L
L
--
D
I
T
N
I
S
Q
V
Q
Q
V
V
Q
E
I
R
P
H
I
I
I
H
C
A
A
--
Y
T
K
V
D
Q
A
E
K
E
-
R
D
L
A
Y
V
I
N
A
I
G
A
R
N
V
A
V
A
S
Q
L
V
G
A
K
L
V
Y
I
S
T
D
Y
V
F
Q
G
D
R
P
E
G
Y
D
E
F
H
N
P
A
P
I
N
I
Y
G
A
S
K
Y
A
G
E
Q
F
V
K
E
L
H
N
K
Y
F
I
V
-
R
T
S
W
L
Y
G
---
K
Y
G
N
N
F
V
K
T
M
I
-
R
L
G
K
-
E
R
E
E
I
S
V
V
A
D
Q
I
G
S
P
T
Y
V
A
D
L
N
V
M
----
I
N
K
L
I
-
H
T
----
S
L
Y
----
G
T
Y
H
V
S
N
T
G
S
C
S
W
F
E
F
A
K
K
I
--
F
---
S
Y
A
N
-
M
K
V
N
-----
V
L
--
P
V
S
T
E
E
F
G
A
A
A
A
R
P
K
Y
S
I
F
Q
-
H
N
M
L
R
-
L
N
G
F
-
L
Q
M
P
S
-----
W
E
E
G
L
E
R
F
F
I
----------
21
PsiBlast_CBE
85.78
41%
-77
- C1 -
3SC6
2
?
F:
[8-280]
-----
V
I
I
T
G
A
N
G
Q
L
G
K
Q
L
Q
E
E
L
N
P
-
E
E
-------
Y
D
I
Y
P
F
-------
D
K
K
L
L
--
D
I
T
N
I
S
Q
V
Q
Q
V
V
Q
E
I
R
P
H
I
I
I
H
C
A
A
--
Y
T
K
V
D
Q
A
E
K
E
-
R
D
L
A
Y
V
I
N
A
I
G
A
R
N
V
A
V
A
S
Q
L
V
G
A
K
L
V
Y
I
S
T
D
Y
V
F
Q
G
D
R
P
E
G
Y
D
E
F
H
N
P
A
P
I
N
I
Y
G
A
S
K
Y
A
G
E
Q
F
V
K
E
L
H
N
K
Y
F
I
V
-
R
T
S
W
L
Y
G
---
K
Y
G
N
N
F
V
K
T
M
I
-
R
L
G
K
-
E
R
E
E
I
S
V
V
A
D
Q
I
G
S
P
T
Y
V
A
D
L
N
V
M
----
I
N
K
L
I
-
H
T
---
S
-
L
Y
----
G
T
Y
H
V
S
N
T
G
S
C
S
W
F
E
F
A
K
K
I
--
F
---
S
Y
-
A
-
N
-
M
K
-----
V
N
VL
P
V
S
T
E
E
F
G
A
A
A
A
R
P
K
Y
S
I
F
Q
H
N
M
L
R
L
-
N
-
G
F
L
Q
M
-
P
S
-----
W
E
E
G
L
E
R
F
------------
2
PsiBlast_PDB
84.84
45%
-82
- C1 -
1VL0
2
?
A:
[15-263]
-----
I
L
I
T
G
A
N
G
Q
L
G
R
E
I
Q
K
Q
L
K
G
-
K
N
-------
V
E
V
I
P
T
-------
D
V
Q
D
L
--
D
I
T
N
V
L
A
V
N
K
F
F
N
E
K
K
P
N
V
V
I
N
C
A
A
--
H
T
A
V
D
K
C
E
E
Q
Y
-
D
L
A
Y
K
I
N
A
I
G
P
K
N
L
A
A
A
A
Y
S
V
G
A
E
I
V
Q
I
S
T
D
Y
V
F
D
G
E
A
K
E
P
I
T
E
F
D
E
V
N
P
Q
S
A
Y
G
K
T
K
L
E
G
E
N
F
V
K
A
L
N
P
K
Y
Y
I
V
-
R
T
A
W
L
Y
G
---
D
-
G
N
N
F
V
K
T
M
I
-
N
L
G
K
-
T
H
D
E
L
K
V
V
H
D
Q
V
G
T
P
T
S
T
V
D
L
A
R
V
----
V
L
K
V
I
D
E
K
---
N
--
Y
----
G
T
F
H
C
T
C
K
G
I
C
S
W
Y
D
F
A
V
E
I
F
R
L
---
T
G
-
I
-
D
-
V
K
-----
V
T
--
P
C
T
T
E
E
F
P
R
P
A
K
R
P
K
Y
S
V
L
-------------------------------------------
55
Fugue
79.51
34%
-81
- C1 -
4NDN
1
MAT2B_HUMAN
F:
[15-323]
IPN
R
R
V
L
V
T
G
A
T
G
L
L
G
R
A
V
H
K
E
F
Q
Q
-
N
N
-------
W
H
A
V
G
C
GFRRARP
K
F
E
Q
V
--
N
L
L
D
S
N
A
V
H
H
I
I
H
D
F
Q
P
H
V
I
V
H
C
A
A
ER
R
P
D
V
D
A
A
S
--------
Q
L
N
V
D
A
S
G
N
L
A
K
E
A
A
A
V
G
A
F
L
I
Y
I
S
S
D
Y
V
F
D
G
T
N
P
P
-
Y
R
E
E
D
I
P
A
P
L
N
L
Y
G
K
T
K
L
D
G
E
K
A
V
L
E
N
N
L
G
A
A
V
L
-
R
I
P
I
L
Y
G
EVE
K
L
E
E
S
A
V
T
V
M
F
-
D
K
V
Q
F
S
N
K
S
A
N
M
D
H
W
Q
Q
R
F
P
T
H
V
K
D
V
A
T
V
----
C
R
Q
L
A
-
E
K
---
R
M
L
D
PSIK
G
T
F
H
W
S
G
N
E
Q
M
T
K
Y
E
M
A
C
A
I
--
A
---
D
A
-
F
-
N
-
L
P
SSH--
L
R
--
P
I
T
-
D
S
P
V
L
G
A
Q
R
P
R
N
A
Q
L
D
C
S
K
L
E
T
-
L
-
G
I
-
G
Q
-
R
T
PFRIG
I
K
E
S
L
W
P
F
L
I
DKRWRQTVFH
3
PsiBlast_PDB
79.11
35%
-70
- C1 -
1KBZ
-
RMLD_SALTY
A:
[1-289]
---
M
N
I
L
L
F
G
K
T
G
Q
V
G
W
E
L
Q
R
S
L
A
P
V
G
N
-------
L
I
A
L
D
V
-------
H
S
K
E
F
CG
D
F
S
N
P
K
G
V
A
E
T
V
R
K
L
R
P
D
V
I
V
N
A
A
A
--
H
T
A
V
D
K
A
E
S
E
-
P
E
L
A
Q
L
L
N
A
T
S
V
E
A
I
A
K
A
A
N
E
T
G
A
W
V
V
H
Y
S
T
D
Y
V
F
P
G
T
G
D
I
P
W
Q
E
T
D
A
T
S
P
L
N
V
Y
G
K
T
K
L
A
G
E
K
-
A
L
Q
D
N
C
P
K
H
L
I
F
R
T
S
W
V
Y
A
---
G
K
G
N
N
F
A
K
T
M
L
-
R
L
A
K
-
E
R
Q
T
L
S
V
I
N
D
Q
Y
G
A
P
T
G
A
E
L
L
A
D
C
T
A
H
A
I
R
V
A
L
-
N
K
---
P
E
V
A
----
G
L
Y
H
L
V
A
G
G
T
T
T
W
H
D
Y
A
A
L
V
--
F
D
E
A
R
K
-
A
-
G
-
I
T
LALT
E
L
N
--
A
V
P
T
S
A
Y
P
T
P
A
S
R
P
G
N
S
R
L
N
T
E
K
F
Q
R
N
F
-
D
L
-
I
L
-
P
Q
-----
W
E
L
G
V
K
R
M
------------
10
PsiBlast_PDB
78.00
31%
-81
- C1 -
4NDN
2
MAT2B_HUMAN
E:
[20-294]
-----
V
L
V
T
G
A
T
G
L
L
G
R
A
V
H
K
E
F
Q
Q
-
N
N
WH
A
V
G
C
G
F
R
R
A
R
P
-------
K
F
E
Q
V
--
N
L
L
D
S
N
A
V
H
H
I
I
H
D
F
Q
P
H
V
I
V
H
C
A
A
--
E
R
R
P
D
V
V
E
N
Q
-
P
D
A
A
S
Q
L
N
V
D
A
S
G
N
L
A
K
E
A
A
A
V
G
A
F
L
I
Y
I
S
S
D
Y
V
F
D
G
T
N
P
-
P
Y
R
E
E
D
I
P
A
P
L
N
L
Y
G
K
T
K
L
D
G
E
K
A
V
L
E
N
N
L
G
A
A
V
L
-
R
I
P
I
L
Y
G
EVE
K
L
E
E
S
A
V
T
V
M
F
D
K
V
Q
F
-
S
N
K
S
A
N
M
D
H
W
Q
Q
R
F
P
T
H
V
K
D
V
A
T
V
----
C
R
Q
L
A
-
E
K
RML
D
P
S
I
K
---
G
T
F
H
W
S
G
N
E
Q
M
T
K
Y
E
M
A
C
A
I
--
A
---
D
A
-
F
-
N
-
L
P
S
S
H--
L
R
--
P
I
T
-
D
S
P
V
L
G
A
Q
R
P
R
N
A
Q
L
D
C
S
K
L
E
T
-
L
-
G
I
-------------------------------
8
PsiBlast_PDB
76.40
31%
-80
- C1 -
4KTV
1
MAT2B_HUMAN
E:
[24-298]
-----
V
L
V
T
G
A
T
G
L
L
G
R
A
V
H
K
E
F
Q
Q
-
N
N
WH
A
V
G
C
G
F
R
R
A
R
P
-------
K
F
E
Q
V
--
N
L
L
D
S
N
A
V
H
H
I
I
H
D
F
Q
P
H
V
I
V
H
C
A
A
--
E
R
R
P
D
V
V
E
N
Q
-
P
D
A
A
S
Q
L
N
V
D
A
S
G
N
L
A
K
E
A
A
A
V
G
A
F
L
I
Y
I
S
S
D
Y
V
F
D
G
T
N
P
-
P
Y
R
E
E
D
I
P
A
P
L
N
L
Y
G
K
T
K
L
D
G
E
K
A
V
L
E
N
N
L
G
A
A
V
L
-
R
I
P
I
L
Y
G
EV
E
K
L
E
E
S
A
V
T
V
M
F
D
K
V
Q
F
-
S
N
K
S
A
N
M
D
H
W
Q
Q
R
F
P
T
H
V
K
D
V
A
T
V
----
C
R
Q
L
A
-
E
K
R
M
L
D
P
S
I
K
---
G
T
F
H
W
S
G
N
E
Q
M
T
K
Y
E
M
A
C
A
I
--
A
---
D
A
-
F
-
N
-
L
P
SSH--
L
R
--
P
I
T
-
D
S
P
V
L
G
A
Q
R
P
R
N
A
Q
L
D
C
S
K
L
E
T
-
L
-
G
I
-------------------------------
7
PsiBlast_PDB
76.32
31%
-76
- C1 -
4KTT
-
MAT2B_HUMAN
E:
[24-298]
-----
V
L
V
T
G
A
T
G
L
L
G
R
A
V
H
K
E
F
Q
Q
-
N
N
WH
A
V
G
C
G
F
R
R
A
R
P
-------
K
F
E
Q
V
--
N
L
L
D
S
N
A
V
H
H
I
I
H
D
F
Q
P
H
V
I
V
H
C
A
A
--
E
R
R
P
D
V
V
E
N
Q
-
P
D
A
A
S
Q
L
N
V
D
A
S
G
N
L
A
K
E
A
A
A
V
G
A
F
L
I
Y
I
S
S
D
Y
V
F
D
G
T
N
P
-
P
Y
R
E
E
D
I
P
A
P
L
N
L
Y
G
K
T
K
L
D
G
E
K
A
V
L
E
N
N
L
G
A
A
V
L
-
R
I
P
I
L
Y
G
EVE
K
L
E
E
S
A
V
T
V
M
F
D
K
V
Q
F
-
S
N
K
S
A
N
M
D
H
W
Q
Q
R
F
P
T
H
V
K
D
V
A
T
V
----
C
R
Q
L
A
-
E
K
R
M
L
D
P
S
I
K---
G
T
F
H
W
S
G
N
E
Q
M
T
K
Y
E
M
A
C
A
I
--
A
---
D
A
-
F
-
N
-
L
P
SSH--
L
R
--
P
I
T
-
D
S
P
V
L
--
Q
R
P
R
N
A
Q
L
D
C
S
K
L
E
T
-
L
-
G
I
-------------------------------
5
PsiBlast_PDB
76.19
35%
-69
- C1 -
1KC3
2
RMLD_SALTY
A:
[1-289]
---
M
N
I
L
L
F
G
K
T
G
Q
V
G
W
E
L
Q
R
S
L
A
P
V
G
N
-------
L
I
A
L
D
V
-------
H
S
K
E
F
CG
D
F
S
N
P
K
G
V
A
E
T
V
R
K
L
R
P
D
V
I
V
N
A
A
A
--
H
T
A
V
D
K
A
E
S
E
-
P
E
L
A
Q
L
L
N
A
T
S
V
E
A
I
A
K
A
A
N
E
T
G
A
W
V
V
H
Y
S
T
D
Y
V
F
P
G
T
G
D
I
P
W
Q
E
T
D
A
T
S
P
L
N
V
Y
G
K
T
K
L
A
G
E
K
-
A
L
Q
D
N
C
P
K
H
L
I
F
R
T
S
W
V
Y
A
---
G
K
G
N
N
F
A
K
T
M
L
-
R
L
A
K
-
E
R
Q
T
L
S
V
I
N
D
Q
Y
G
A
P
T
G
A
E
L
L
A
D
C
T
A
H
A
I
R
V
A
L
-
N
K
---
P
E
V
A
----
G
L
Y
H
L
V
A
G
G
T
T
T
W
H
D
Y
A
A
L
V
--
F
D
E
A
R
K
-
A
-
G
-
I
T
LALT
E
L
N
--
A
V
P
T
S
A
Y
P
T
P
A
S
R
P
G
N
S
R
L
N
T
E
K
F
Q
R
N
F
-
D
L
-
I
L
-
P
Q
-----
W
E
L
G
V
K
R
M
------------
6
PsiBlast_PDB
75.88
35%
-68
- C1 -
1N2S
1
RMLD_SALTY
A:
[1-289]
---
M
N
I
L
L
F
G
K
T
G
Q
V
G
W
E
L
Q
R
S
L
A
P
V
G
N
-------
L
I
A
L
D
V
-------
H
S
K
E
F
CG
D
F
S
N
P
K
G
V
A
E
T
V
R
K
L
R
P
D
V
I
V
N
A
A
A
--
H
T
A
V
D
K
A
E
S
E
-
P
E
L
A
Q
L
L
N
A
T
S
V
E
A
I
A
K
A
A
N
E
T
G
A
W
V
V
H
Y
S
T
D
Y
V
F
P
G
T
G
D
I
P
W
Q
E
T
D
A
T
S
P
L
N
V
Y
G
K
T
K
L
A
G
E
K
-
A
L
Q
D
N
C
P
K
H
L
I
F
R
T
S
W
V
Y
A
---
G
K
G
N
N
F
A
K
T
M
L
-
R
L
A
K
-
E
R
Q
T
L
S
V
I
N
D
Q
Y
G
A
P
T
G
A
E
L
L
A
D
C
T
A
H
A
I
R
V
A
L
-
N
K
---
P
E
V
A
----
G
L
Y
H
L
V
A
G
G
T
T
T
W
H
D
Y
A
A
L
V
--
F
D
E
A
R
K
-
A
-
G
-
I
T
LALT
E
L
N
--
A
V
P
T
S
A
Y
P
T
P
A
S
R
P
G
N
S
R
L
N
T
E
K
F
Q
R
N
F
-
D
L
-
I
L
-
P
Q
-----
W
E
L
G
V
K
R
M
------------
26
PsiBlast_CBE
75.58
31%
-76
- C1 -
2YDX
7
MAT2B_HUMAN
E:
[5-278]
-----
V
L
V
T
G
A
T
G
L
L
G
R
A
V
H
K
E
F
Q
Q
-
N
N
WHAVGCG
F
R
R
A
R
P
-------
K
F
E
Q
V
--
N
L
L
D
S
N
A
V
H
H
I
I
H
D
F
Q
P
H
V
I
V
H
C
A
A
--
E
R
R
P
D
V
V
E
N
Q
-
P
D
A
A
S
Q
L
N
V
D
A
S
G
N
L
A
K
E
A
A
A
V
G
A
F
L
I
Y
I
S
S
D
Y
V
F
D
G
T
N
P
-
P
Y
R
E
E
D
I
P
A
P
L
N
L
Y
G
K
T
K
L
D
G
E
K
A
V
L
E
N
N
L
G
A
A
V
L
-
R
I
P
I
L
Y
G
EVE
K
L
E
E
S
A
V
T
V
M
F
D
K
V
Q
F
-
S
N
K
S
A
N
M
D
H
W
Q
Q
R
F
P
T
H
V
K
D
V
A
T
V
----
C
R
Q
L
A
-
E
K
RML
D
P
S
I
K---
G
T
F
H
W
S
G
N
E
Q
M
T
K
Y
E
M
A
C
A
I
--
A
---
D
A
-
F
-
N
-
L
P
SSH--
L
R
--
P
I
T
-
D
S
P
V
L
G
A
Q
R
P
R
N
A
Q
L
D
C
S
K
L
E
T
-
L
-
G
--------------------------------
4
PsiBlast_PDB
75.48
35%
-72
- C1 -
1KC1
3
RMLD_SALTY
A:
[1-289]
---
M
N
I
L
L
F
G
K
T
G
Q
V
G
W
E
L
Q
R
S
L
A
P
V
G
N
-------
L
I
A
L
D
V
-------
H
S
K
E
F
CG
D
F
S
N
P
K
G
V
A
E
T
V
R
K
L
R
P
D
V
I
V
N
A
A
A
--
H
T
A
V
D
K
A
E
S
E
-
P
E
L
A
Q
L
L
N
A
T
S
V
E
A
I
A
K
A
A
N
E
T
G
A
W
V
V
H
Y
S
T
D
Y
V
F
P
G
T
G
D
I
P
W
Q
E
T
D
A
T
S
P
L
N
V
Y
G
K
T
K
L
A
G
E
K
-
A
L
Q
D
N
C
P
K
H
L
I
F
R
T
S
W
V
Y
A
---
G
K
G
N
N
F
A
K
T
M
L
-
R
L
A
K
-
E
R
Q
T
L
S
V
I
N
D
Q
Y
G
A
P
T
G
A
E
L
L
A
D
C
T
A
H
A
I
R
V
A
L
-
N
K
---
P
E
V
A
----
G
L
Y
H
L
V
A
G
G
T
T
T
W
H
D
Y
A
A
L
V
--
F
D
E
A
R
K
-
A
-
G
-
I
T
LALT
E
L
N
--
A
V
P
T
S
A
Y
P
T
P
A
S
R
P
G
N
S
R
L
N
T
E
K
F
Q
R
N
F
-
D
L
-
I
L
-
P
Q
-----
W
E
L
G
V
K
R
M
------------
28
PsiBlast_CBE
75.32
31%
-75
- C1 -
2YDX
6
MAT2B_HUMAN
C:
[5-278]
-----
V
L
V
T
G
A
T
G
L
L
G
R
A
V
H
K
E
F
Q
Q
-
N
N
WHAVGCG
F
R
R
A
R
P
-------
K
F
E
Q
V
--
N
L
L
D
S
N
A
V
H
H
I
I
H
D
F
Q
P
H
V
I
V
H
C
A
A
--
E
R
R
P
D
V
V
E
N
Q
-
P
D
A
A
S
Q
L
N
V
D
A
S
G
N
L
A
K
E
A
A
A
V
G
A
F
L
I
Y
I
S
S
D
Y
V
F
D
G
T
N
P
-
P
Y
R
E
E
D
I
P
A
P
L
N
L
Y
G
K
T
K
L
D
G
E
K
A
V
L
E
N
N
L
G
A
A
V
L
-
R
I
P
I
L
Y
G
EVE
K
L
E
E
S
A
V
T
V
M
F
D
K
V
Q
F
-
S
N
K
S
A
N
M
D
H
W
Q
Q
R
F
P
T
H
V
K
D
V
A
T
V
----
C
R
Q
L
A
-
E
K
RML
D
P
S
I
K---
G
T
F
H
W
S
G
N
E
Q
M
T
K
Y
E
M
A
C
A
I
--
A
---
D
A
-
F
-
N
-
L
P
SSH--
L
R
--
P
I
T
-
D
S
P
V
L
G
A
Q
R
P
R
N
A
Q
L
D
C
S
K
L
E
T
-
L
-
G
--------------------------------
9
PsiBlast_PDB
74.78
31%
-73
- C1 -
2YDX
7
MAT2B_HUMAN
A:
[5-278]
-----
V
L
V
T
G
A
T
G
L
L
G
R
A
V
H
K
E
F
Q
Q
-
N
N
WH
A
V
G
C
G
F
R
R
A
R
P
-------
K
F
E
Q
V
--
N
L
L
D
S
N
A
V
H
H
I
I
H
D
F
Q
P
H
V
I
V
H
C
A
A
--
E
R
R
P
D
V
V
E
N
Q
-
P
D
A
A
S
Q
L
N
V
D
A
S
G
N
L
A
K
E
A
A
A
V
G
A
F
L
I
Y
I
S
S
D
Y
V
F
D
G
T
N
P
-
P
Y
R
E
E
D
I
P
A
P
L
N
L
Y
G
K
T
K
L
D
G
E
K
A
V
L
E
N
N
L
G
A
A
V
L
-
R
I
P
I
L
Y
G
EVE
K
L
E
E
S
A
V
T
V
M
F
D
K
V
Q
F
-
S
N
K
S
A
N
M
D
H
W
Q
Q
R
F
P
T
H
V
K
D
V
A
T
V
----
C
R
Q
L
A
-
E
K
R
M
L
D
P
S
I
K---
G
T
F
H
W
S
G
N
E
Q
M
T
K
Y
E
M
A
C
A
I
--
A
---
D
A
-
F
-
N
-
L
P
SSH--
L
R
--
P
I
T
-
D
S
P
V
L
G
A
Q
R
P
R
N
A
Q
L
D
C
S
K
L
E
T
-
L
-
G
--------------------------------