@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1268: (2016-03-23 )
LFKFNDEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCNEIIEEELGISEFVDFGEVPKPQEIRHILSDYVIGQERAKKALAVAVYNHYKRINSNETKEDEVELSKSNICLIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQSADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQELIQIDTGNILFIVGGAFDGIEQIVKNRMGEKVIGFGTDNAKLKDDETYLSRVVPEDLLKFGLIPEFIGRLPVIATLEQLDEAALVSILTEPKNALVKQYKRMLELDDVELEFEPTALIEIAKEAIERKTGARGLRSIIEQIMLEVMFEIPSRDDITKCIITEKAARGEEEPQLQLEDGSIIPIKTSA
Atome Classification :
(21 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260-.......270..--.....----280.......290.......300.......310.......320.......330.......340.......350......-----.360.......370.......380.......390.......400.......410.......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
LFKFNDEKG
Q
L
K
C
S
FCGK
T
Q
D
Q
V
R
K
L
VAGP
G
V
Y
I
C
D
E
C
I
E
L
C
N
E
I
I
E
E
E
LG
I
S
E
F
V
DFGEVP
K
P
Q
E
I
R
H
I
L
S
D
Y
VI
G
Q
E
R
A
K
K
A
L
A
V
A
V
Y
N
H
Y
K
RINSNETK
E
D
E
VELSKS
N
I
C
L
IGPTGS
G
K
T
L
L
A
Q
T
L
A
R
I
LNVPFAIADATSLTEAGYV
G
E
D
V
E
N
I
L
L
K
L
I
Q
SADY
D
V
E
K
AEK
G
I
I
Y
I
D
E
I
D
K
V
A
RKSENPSITRDVS
G
E
G
V
Q
Q
A
L
L
K
I
L
E
G
T
V
ASVPPQGGRKH
P
H
Q
E
L
I
Q
IDTG
N
I
L
F
I
VGG
A
F
D
G
I
E
Q
I
V
K
N
RMGE-
K
V
I
G
FGTDNAKL--K
D
D
E
T
----
Y
L
S
R
V
V
P
E
D
L
L
K
FG
L
I
P
E
F
IGRL
P
V
I
A
T
L
E
Q
L
D
E
A
A
L
V
S
I
LTEP
K
N
A
L
V
K
Q
Y
K
R
M
LELD
D
V
E
L
EFE
P
T
A
L
I
E
I
A
K
E
A
I
E
-----
R
KT
G
A
R
G
L
R
S
I
I
E
Q
I
M
L
E
V
M
F
EIP
S
R
D
D
I
T
K
C
I
I
T
E
KAARGEEEP
Q
L
Q
LEDG
S
I
I
P
I
KTSA
42
PsiBlast_CBE
95.65
63%
-125
- C3 -
3HWS
4
CLPX_ECOLI
B:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
T
S
-
N
G
V
E
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
T
E
A
G
Y
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
Q
I
D
K
I
S
R
-------------
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
---------
R
K
H
P
Q
Q
E
F
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
T
-------------------
A
S
E
G
E
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
--------------
23
PsiBlast_CBE
95.14
64%
-128
- C3 -
4I63
1
CLPX_ECOLI
D:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
T
S
----
E
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
T
--
G
Y
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
E
I
D
K
I
S
R
K
S
D
N
P
---
R
D
V
S
G
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
----------------
F
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
T
-
G
S
-----------------S
E
G
E
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
--------------
41
PsiBlast_CBE
94.99
63%
-129
- C3 -
3HWS
3
CLPX_ECOLI
D:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
T
S
-
N
G
V
E
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
T
E
A
G
Y
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
Q
I
D
K
I
S
R
----------
V
S
G
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
V
A
A
V
P
-------------
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
T
-
G
-----------------
A
S
E
G
E
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
--------------
26
PsiBlast_CBE
94.96
64%
-122
- C3 -
4I5O
1
CLPX_ECOLI
E:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
T
S
-
N
G
V
E
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
T
E
A
G
Y
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
E
I
D
K
I
S
R
K
S
D
N
P
---
R
D
V
S
G
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
----------------
F
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
T
-
G
S
----------------
A
SE
G
E
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
--------------
22
PsiBlast_CBE
94.58
64%
-124
- C3 -
4I63
1
CLPX_ECOLI
E:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
T
S
----
E
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
T
--
G
Y
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
E
I
D
K
I
S
R
K
S
D
N
P
---
R
D
V
S
G
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
----------------
F
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
T
-
G
S
--------------
D
K
A
S
E
G
E
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
--------------
3
PsiBlast_PDB
94.27
64%
-129
- C3 -
4I63
1
CLPX_ECOLI
A:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
T
S
-----
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
T
--
G
Y
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
E
I
D
K
I
S
R
K
S
D
N
P
---
R
D
V
S
G
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
----------------
F
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
T
-
G
S
-----------------S
E
G
E
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
--------------
136
HHSearch
94.18
62%
-117
- C3 -
3HWS
4
CLPX_ECOLI
A:
[3-352]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
T
S
-
N
G
V
E
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
T
E
A
G
Y
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
Q
I
D
K
I
S
R
K
S
D
N
P
---
R
D
V
S
G
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
----------------
F
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
T
G
S
-----------DK
A
S
E
G
E
----
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
I
Y
------------
5
PsiBlast_PDB
94.00
63%
-121
- C3 -
3HWS
4
CLPX_ECOLI
A:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
T
S
-
N
G
V
E
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
T
E
A
G
Y
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
Q
I
D
K
I
S
R
K
S
D
N
P
---
R
D
V
S
G
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
----------------
F
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
T
-
G
S
--------------
D
K
A
S
E
G
E
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
--------------
24
PsiBlast_CBE
93.90
64%
-130
- C3 -
4I63
1
CLPX_ECOLI
B:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
T
S
-----
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
T
--
G
Y
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
E
I
D
K
I
S
R
K
-------
R
D
V
S
G
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
----------------
F
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
T
-
G
S
-----------------S
E
G
E
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
--------------
34
PsiBlast_CBE
93.75
64%
-130
- C3 -
4I4L
1
CLPX_ECOLI
B:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
T
----
V
E
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
---
G
Y
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
E
I
D
K
I
S
R
K
--------
D
V
S
G
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
----------------
F
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
T
-------------------
A
S
E
G
E
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
--------------
36
PsiBlast_CBE
93.50
64%
-122
- C3 -
4I34
1
CLPX_ECOLI
B:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
T
S
-
N
G
V
E
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
T
E
A
G
Y
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
E
I
D
K
I
S
R
K
--------
D
V
S
G
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
----------------
F
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
T
-
G
S
----------------
A
S
E
G
E
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
--------------
2
PsiBlast_PDB
93.49
64%
-131
- C3 -
4I5O
1
CLPX_ECOLI
A:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
T
S
-
N
---
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
---
G
Y
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
E
I
D
K
I
S
R
K
S
------
R
D
V
S
G
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
----------------
F
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
T
-
G
S
----------------
A
S
E
G
E
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
--------------
29
PsiBlast_CBE
93.47
64%
-129
- C3 -
4I5O
1
CLPX_ECOLI
B:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
--------
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
T
E
A
G
Y
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
E
I
D
K
I
S
R
K
S
------
R
D
V
S
G
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
----------------
F
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
T
-
G
S
----------------
A
S
E
G
E
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
--------------
1
PsiBlast_PDB
93.22
64%
-125
- C3 -
4I34
1
CLPX_ECOLI
A:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
T
S
-
N
G
V
E
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
T
E
A
G
Y
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
E
I
D
K
I
S
R
K
S
D
N
P
---
R
D
V
S
G
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
----------------
F
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
T
-------------------
A
S
E
G
E
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
--------------
27
PsiBlast_CBE
93.12
64%
-131
- C3 -
4I5O
1
CLPX_ECOLI
D:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
-------
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
T
E
A
G
Y
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
E
I
D
K
I
S
R
---------
D
V
S
G
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
----------------
F
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
T
-------------------
A
S
E
G
E
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
--------------
31
PsiBlast_CBE
92.95
64%
-132
- C3 -
4I4L
2
CLPX_ECOLI
E:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
--------
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
T
-
A
G
Y
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
E
I
D
K
I
S
R
-------------
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
-----------------
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
---------------------E
G
E
-
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
--------------
28
PsiBlast_CBE
92.70
64%
-116
- C3 -
4I5O
1
CLPX_ECOLI
C:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
T
S
-
N
G
V
E
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
T
E
A
G
Y
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
E
I
D
K
I
S
R
K
S
D
N
P
---
R
D
V
S
G
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
----------------
F
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
T
-
G
S
----------------
A
S
E
G
E
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
--------------
40
PsiBlast_CBE
92.46
63%
-122
- C3 -
3HWS
1
CLPX_ECOLI
E:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
T
S
-
N
G
V
E
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
T
E
A
G
Y
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
Q
I
D
K
I
S
R
-------------
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
V
A
A
-------------
F
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
T
-
G
S
----------------
A
SEGE
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
--------------
32
PsiBlast_CBE
92.37
64%
-127
* C3 *
4I4L
1
CLPX_ECOLI
D:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
T
S
---
V
E
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
T
--
G
Y
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
E
I
D
K
I
S
R
K
S
------
R
D
V
S
G
E
G
V
Q
Q
A
L
L
K
L
I
E
G
T
----------------
F
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
T
-------------------
A
S
E
G
E
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
--------------
38
PsiBlast_CBE
92.28
63%
-132
- C3 -
4I81
1
CLPX_ECOLI
B:
[3-350]
------------------------------------------------------------
L
P
T
P
H
E
I
R
N
H
L
D
D
Y
V
I
G
Q
E
Q
A
K
K
V
L
A
V
A
V
Y
N
H
Y
K
R
L
R
N
G
D
T
S
-
N
G
V
E
L
G
K
S
N
I
L
L
I
G
P
T
G
S
G
K
T
L
L
A
E
T
L
A
R
L
L
D
V
P
F
T
M
A
D
A
T
T
L
-----
V
G
E
D
V
E
N
I
I
Q
K
L
L
Q
K
C
D
Y
D
V
Q
K
A
Q
R
G
I
V
Y
I
D
Q
I
D
K
I
S
R
K
-------------
G
V
Q
Q
A
L
L
K
L
I
E
G
T
-----------------
L
Q
V
D
T
S
K
I
L
F
I
C
G
G
A
F
A
G
L
D
K
V
I
S
H
R
V
E
T
-------------------
A
S
E
G
E
L
L
A
Q
V
E
P
E
D
L
I
K
F
G
L
I
P
E
F
I
G
R
L
P
V
V
A
T
L
N
E
L
S
E
E
A
L
I
Q
I
L
K
E
P
K
N
A
L
T
K
Q
Y
Q
A
L
F
N
L
E
G
V
D
L
E
F
R
D
E
A
L
D
A
I
A
K
K
A
M
A
-----
R
K
T
G
A
R
G
L
R
S
I
V
E
A
A
L
L
D
T
M
Y
D
L
P
S
M
E
D
V
E
K
V
V
I
D
E
S
V
I
D
G
Q
S
E
P
L
L
--------------
137
HHSearch
45.67
36%
-84
- C3 -
1G41
2
HSLU_HAEIN
A:
[249-440]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
Q
N
G
I
V
F
I
D
E
I
D
K
I
C
K
K
G
E
Y
S
--
G
A
D
V
S
R
E
G
V
Q
R
D
L
L
P
L
V
E
G
S
T
V
S
-----------
T
K
H
G
M
V
K
T
D
H
I
L
F
I
A
S
G
A
F
Q
V
--------------------------------------------
A
R
P
S
D
L
I
P
E
L
Q
G
R
L
P
I
R
V
E
L
T
A
L
S
A
A
D
F
E
R
I
L
T
E
P
H
A
S
L
T
E
Q
Y
K
A
L
M
A
T
E
G
V
N
I
A
F
T
T
D
A
V
K
K
I
A
E
A
A
F
R
V
N
E
K
T
E
N
I
G
A
R
R
L
H
T
V
M
E
R
L
M
D
K
I
S
F
S
A
S
D
M
N
G
-
Q
T
V
N
I
D
A
A
Y
V
A
D
A
L
G
E
V
V
E
N
E
D
L
S
--------