@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1287: (2016-03-23 )
LSNPEQHIQDLALEEVMGDRFGRYSKYIIQERALPDVRDGLKPVQRRILFAMNVEGNTAEKGFRKSAKTVGNVIGNYHPHGDSSVYEAMVRMSQDWKVRNMLIEMHGNNGSVDGDPPAAMRYTEARLSPISAELLRDIEKETVDFIPNFDDTSSEPTVLPARFPNLLVNGSTGISAGYATDIPPHNLTEIIEAVIKRLDNPLCTTDDIMKIVKGPDFPTGGIIQGIDGIRKAYQTGKGRVVVRSKTEIEDIRGGRKQITIHEIPYEVNKANLVKRMDELRIEKKIEGISEVRDETDRTGLRIAVELKKDANAEGVLNYLFKNTDLQVSYNFNMVAINKKRPELMGIIPMLDAYIEHQKEIITKRSEYDIRKARARQHILEGLIKALSILDEVIKLIRGSKDKRDAKLNLQTKYDFSEKQAEAIVSLQLYRLTNTDIHELQSEAKSLAEQISVLEKILGDEAELIAVLKEELAEIKKKYKTARRTEVQAEIAEIKIDTEVLVANEDVIVSVTKEGYVKRTSQRSYAASNGAELAMKEADHAIFIQKMNSLDSLLLFTSKGNFIYRPVHELPDIRWKNLGDHVSHLASDLSAGEEIRSAIAIQAFTEEKRFLFVTKNGMTKQSAITNYKPQRYSKSMMAIKLKGDDELLSVHLIDGTEDIFLATKNGYGLRYSITEIPESGARTAGVKAINLKQDDIVIGGIVLMPNEQKHILLATQRGSLKQMKASEFEPISRAKRGLLMLRELKSNPHRFIGITLADNNDHLFIETNTDQIVEIDVANLRITDRYSNGSFVLDETMEGEPTSIWLAIPEIKDTSDAKEE
Atome Classification :
(35 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.----.----.....210.......220.......230.......240.......-250.......260.......270.......280.......290..-..-.-..300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410------------------------------.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810.......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
LS
N
P
E
Q
H
I
Q
D
L
A
L
E
E
V
M
G
D
RF
G
R
Y
S
K
Y
I
I
Q
ERAL
P
D
V
R
D
G
L
K
P
V
Q
R
R
I
L
F
A
M
NVEGN
T
A
E
K
G
F
R
K
S
A
K
T
V
G
N
V
IGNYHPHG
D
S
S
V
Y
E
A
M
V
RMSQDW
K
V
R
N
M
L
I
E
M
HGNNGSVDGDPP
A
A
M
R
Y
T
E
ARLSP
I
S
A
E
L
L
R
D
I
E
K
E
T
V
DFIPNFDDTSSEP
T
V
LPARFP
N
L
L
VNGSTGISAGYATDIPP
H
N
L
T
E
I
I
E
A
V
I
K
RLDNPLC----
T
----
T
D
D
I
M
K
I
VKGPDFPT
G
G
I
I
Q
G
I
D
G
I
R
K
A
Y
QTGK
G
R
V
V
V
RSKT
E
I
E
-
D
IRGG
R
K
Q
I
T
I
HEIPYEV
N
K
A
N
L
V
K
R
M
D
E
L
R
I
E
K
K
I
E
G
I
S
E
V
RDE-TD-R-TG
L
R
I
A
V
E
LKKDA
N
A
E
G
V
L
N
Y
L
FKNT
D
L
Q
V
S
Y
N
F
N
M
V
A
INKKRPE
L
M
G
I
I
P
M
L
D
A
Y
I
E
H
Q
K
E
I
I
T
KRSE
Y
D
I
R
K
A
R
A
R
Q
H
I
L
E
G
L
I
K
A
L
S
I
L
D
E
V
I
K
L
IRGSKDKRD
A
K
L
N
L
Q
T
K------------------------------YDF
S
E
K
Q
A
E
A
I
V
S
L
Q
L
Y
RLTNT
D
I
H
E
L
Q
S
E
A
K
S
L
A
E
Q
I
S
V
L
E
K
I
LGD
E
A
E
L
I
A
V
L
K
E
E
L
A
E
I
K
K
K
Y
K
TAR
R
T
E
V
Q
A
E
I
A
E
I
K
I
D
T
E
V
L
V
ANE
D
V
I
V
S
VTKEG
Y
V
KRTSQRSYAASNG
A
E
L
A
M
KEAD
H
A
I
F
I
Q
K
M
NSLD
S
L
L
L
F
TSKG
N
F
I
Y
R
P
V
H
ELPDI
R
W
K
N
L
G
D
H
V
S
H
L
A
S
D
L
SA
G
E
E
I
R
S
A
I
A
I
Q
A
FTEE
K
R
F
L
F
V
TKNGMTK
Q
S
AITNYK
P
Q
RYSK
S
M
M
A
I
K
LKGDD
E
L
L
S
V
H
L
IDGT
E
D
I
F
L
A
TKNGY
G
L
R
Y
S
I
TEIPESGARTAG
V
K
A
I
NLKQD
D
I
V
I
G
G
I
V
LMPNEQ
K
H
I
L
L
A
TQRG
S
L
K
Q
MKASEFE
P
I
S
R
A
K
R
G
L
L
M
L
R
E
LKSNP
H
R
F
I
G
I
T
L
ADNN
D
H
L
F
I
ETNTD
Q
I
V
E
I
D
VA
N
L
R
I
T
D
RYSNG
S
F
V
L
DETMEGEP
T
S
I
W
L
AIPEIKDTSDAKEE
8
PsiBlast_PDB
92.19
65%
-62
- C2 -
3RAF
5
PARC_STRPN
A:
[3-483]
------
N
I
Q
N
M
S
L
E
D
I
M
G
E
R
F
G
R
Y
S
K
Y
I
I
Q
D
R
A
L
P
D
I
R
D
G
L
K
P
V
Q
R
R
I
L
Y
S
M
N
K
D
S
N
T
F
D
K
S
Y
R
K
S
A
K
S
V
G
N
I
M
G
N
F
H
P
H
G
D
S
S
I
Y
D
A
M
V
R
M
S
Q
N
W
K
N
R
E
I
L
V
E
M
H
G
N
N
G
S
M
D
G
D
P
P
A
A
M
R
Y
T
E
A
R
L
S
E
I
A
G
Y
L
L
Q
D
I
E
K
K
T
V
P
F
A
W
N
F
D
D
T
E
K
E
P
T
V
L
P
A
A
F
P
N
L
L
V
N
G
S
T
G
I
S
A
G
Y
A
T
D
I
P
P
H
N
L
A
E
V
I
D
A
A
V
Y
M
I
D
H
P
T
A
----
K
----
I
D
K
L
M
E
F
L
P
G
P
D
F
P
T
G
A
I
I
Q
G
R
D
E
I
K
K
A
Y
E
T
G
K
G
R
V
V
V
R
S
K
T
E
I
E
-
K
L
K
G
G
K
E
Q
I
V
I
T
E
I
P
Y
E
I
N
K
A
N
L
V
K
K
I
D
D
V
R
V
N
N
K
V
A
G
I
A
E
V
R
D
E
-
S
D
-
R
-
D
G
L
R
I
A
I
E
L
K
K
D
A
N
T
E
L
V
L
N
Y
L
F
K
Y
T
D
L
Q
I
N
Y
N
F
N
M
V
A
I
D
N
F
T
P
R
Q
V
G
I
V
P
I
L
S
S
Y
I
A
H
R
R
E
V
I
L
A
R
S
R
F
D
K
E
K
A
E
K
R
L
H
I
V
E
G
L
I
R
V
I
S
I
L
D
E
V
I
A
L
I
R
A
S
E
N
K
A
D
A
K
E
N
L
K
V
S
------------------------------
Y
D
F
T
E
E
Q
A
E
A
I
V
T
L
Q
L
Y
R
L
T
N
T
D
V
V
V
L
Q
E
E
E
A
E
L
R
E
K
I
A
M
L
A
A
I
I
G
D
E
R
T
M
Y
N
L
M
K
K
E
L
R
E
V
K
K
K
F
A
T
P
R
L
S
S
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
PsiBlast_PDB
92.17
65%
-64
- C2 -
4KOE
5
PARC_STRPN
A:
[3-483]
------
N
I
Q
N
M
S
L
E
D
I
M
G
E
R
F
G
R
Y
S
K
Y
I
I
Q
D
R
A
L
P
D
I
R
D
G
L
K
P
V
Q
R
R
I
L
Y
S
M
N
K
D
S
N
T
F
D
K
S
Y
R
K
S
A
K
S
V
G
N
I
M
G
N
F
H
P
H
G
D
S
S
I
Y
D
A
M
V
R
M
S
Q
N
W
K
N
R
E
I
L
V
E
M
H
G
N
N
G
S
M
D
G
D
P
P
A
A
M
R
Y
T
E
A
R
L
S
E
I
A
G
Y
L
L
Q
D
I
E
K
K
T
V
P
F
A
W
N
F
D
D
T
E
K
E
P
T
V
L
P
A
A
F
P
N
L
L
V
N
G
S
T
G
I
S
A
G
Y
A
T
D
I
P
P
H
N
L
A
E
V
I
D
A
A
V
Y
M
I
D
H
P
T
A
----
K
----
I
D
K
L
M
E
F
L
P
G
P
D
F
P
T
G
A
I
I
Q
G
R
D
E
I
K
K
A
Y
E
T
G
K
G
R
V
V
V
R
S
K
T
E
I
E
-
K
L
K
G
G
K
E
Q
I
V
I
T
E
I
P
Y
E
I
N
K
A
N
L
V
K
K
I
D
D
V
R
V
N
N
K
V
A
G
I
A
E
V
R
D
E
-
S
D
-
R
-
D
G
L
R
I
A
I
E
L
K
K
D
A
N
T
E
L
V
L
N
Y
L
F
K
Y
T
D
L
Q
I
N
Y
N
F
N
M
V
A
I
D
N
F
T
P
R
Q
V
G
I
V
P
I
L
S
S
Y
I
A
H
R
R
E
V
I
L
A
R
S
R
F
D
K
E
K
A
E
K
R
L
H
I
V
E
G
L
I
R
V
I
S
I
L
D
E
V
I
A
L
I
R
A
S
E
N
K
A
D
A
K
E
N
L
K
V
S
------------------------------
Y
D
F
T
E
E
Q
A
E
A
I
V
T
L
Q
L
Y
R
L
T
N
T
D
V
V
V
L
Q
E
E
E
A
E
L
R
E
K
I
A
M
L
A
A
I
I
G
D
E
R
T
M
Y
N
L
M
K
K
E
L
R
E
V
K
K
K
F
A
T
P
R
L
S
S
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
31
PsiBlast_CBE
92.10
65%
-70
- C2 -
4I3H
3
?
B:
[651-1131]
------
N
I
Q
N
M
S
L
E
D
I
M
G
E
R
F
G
R
Y
S
K
Y
I
I
Q
D
R
A
L
P
D
I
R
D
G
L
K
P
V
Q
R
R
I
L
Y
S
M
N
K
D
S
N
T
F
D
K
S
Y
R
K
S
A
K
S
V
G
N
I
M
G
N
F
H
P
H
G
D
S
S
I
Y
D
A
M
V
R
M
S
Q
N
W
K
N
R
E
I
L
V
E
M
H
G
N
N
G
S
M
D
G
D
P
P
A
A
M
R
Y
T
E
A
R
L
S
E
I
A
G
Y
L
L
Q
D
I
E
K
K
T
V
P
F
A
W
N
F
D
D
T
E
K
E
P
T
V
L
P
A
A
F
P
N
L
L
V
N
G
S
T
G
I
S
A
G
Y
A
T
D
I
P
P
H
N
L
A
E
V
I
D
A
A
V
Y
M
I
D
H
P
T
A
----
K
----
I
D
K
L
M
E
F
L
P
G
P
D
F
P
T
G
A
I
I
Q
G
R
D
E
I
K
K
A
Y
E
T
G
K
G
R
V
V
V
R
S
K
T
E
I
E
-
K
L
K
G
G
K
E
Q
I
V
I
T
E
I
P
Y
E
I
N
K
A
N
L
V
K
K
I
D
D
V
R
V
N
N
K
V
A
G
I
A
E
V
R
D
E
-
S
D
-
R
-
D
G
L
R
I
A
I
E
L
K
K
D
A
N
T
E
L
V
L
N
Y
L
F
K
Y
T
D
L
Q
I
N
Y
N
F
N
M
V
A
I
D
N
F
T
P
R
Q
V
G
I
V
P
I
L
S
S
Y
I
A
H
R
R
E
V
I
L
A
R
S
R
F
D
K
E
K
A
E
K
R
L
H
I
V
E
G
L
I
R
V
I
S
I
L
D
E
V
I
A
L
I
R
A
S
E
N
K
A
D
A
K
E
N
L
K
V
S
------------------------------
Y
D
F
T
E
E
Q
A
E
A
I
V
T
L
Q
L
Y
R
L
T
N
T
D
V
V
V
L
Q
E
E
E
A
E
L
R
E
K
I
A
M
L
A
A
I
I
G
D
E
R
T
M
Y
N
L
M
K
K
E
L
R
E
V
K
K
K
F
A
T
P
R
L
S
S
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
9
PsiBlast_PDB
91.83
65%
-64
- C2 -
3RAD
5
PARC_STRPN
A:
[3-483]
------
N
I
Q
N
M
S
L
E
D
I
M
G
E
R
F
G
R
Y
S
K
Y
I
I
Q
D
R
A
L
P
D
I
R
D
G
L
K
P
V
Q
R
R
I
L
Y
S
M
N
K
D
S
N
T
F
D
K
S
Y
R
K
S
A
K
S
V
G
N
I
M
G
N
F
H
P
H
G
D
S
S
I
Y
D
A
M
V
R
M
S
Q
N
W
K
N
R
E
I
L
V
E
M
H
G
N
N
G
S
M
D
G
D
P
P
A
A
M
R
Y
T
E
A
R
L
S
E
I
A
G
Y
L
L
Q
D
I
E
K
K
T
V
P
F
A
W
N
F
D
D
T
E
K
E
P
T
V
L
P
A
A
F
P
N
L
L
V
N
G
S
T
G
I
S
A
G
Y
A
T
D
I
P
P
H
N
L
A
E
V
I
D
A
A
V
Y
M
I
D
H
P
T
A
----
K
----
I
D
K
L
M
E
F
L
P
G
P
D
F
P
T
G
A
I
I
Q
G
R
D
E
I
K
K
A
Y
E
T
G
K
G
R
V
V
V
R
S
K
T
E
I
E
-
K
L
K
G
G
K
E
Q
I
V
I
T
E
I
P
Y
E
I
N
K
A
N
L
V
K
K
I
D
D
V
R
V
N
N
K
V
A
G
I
A
E
V
R
D
E
-
S
D
-
R
-
D
G
L
R
I
A
I
E
L
K
K
D
A
N
T
E
L
V
L
N
Y
L
F
K
Y
T
D
L
Q
I
N
Y
N
F
N
M
V
A
I
D
N
F
T
P
R
Q
V
G
I
V
P
I
L
S
S
Y
I
A
H
R
R
E
V
I
L
A
R
S
R
F
D
K
E
K
A
E
K
R
L
H
I
V
E
G
L
I
R
V
I
S
I
L
D
E
V
I
A
L
I
R
A
S
E
N
K
A
D
A
K
E
N
L
K
V
S
------------------------------
Y
D
F
T
E
E
Q
A
E
A
I
V
T
L
Q
L
Y
R
L
T
N
T
D
V
V
V
L
Q
E
E
E
A
E
L
R
E
K
I
A
M
L
A
A
I
I
G
D
E
R
T
M
Y
N
L
M
K
K
E
L
R
E
V
K
K
K
F
A
T
P
R
L
S
S
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
91.81
65%
-66
- C2 -
4I3H
4
?
A:
[651-1131]
------
N
I
Q
N
M
S
L
E
D
I
M
G
E
R
F
G
R
Y
S
K
Y
I
I
Q
D
R
A
L
P
D
I
R
D
G
L
K
P
V
Q
R
R
I
L
Y
S
M
N
K
D
S
N
T
F
D
K
S
Y
R
K
S
A
K
S
V
G
N
I
M
G
N
F
H
P
H
G
D
S
S
I
Y
D
A
M
V
R
M
S
Q
N
W
K
N
R
E
I
L
V
E
M
H
G
N
N
G
S
M
D
G
D
P
P
A
A
M
R
Y
T
E
A
R
L
S
E
I
A
G
Y
L
L
Q
D
I
E
K
K
T
V
P
F
A
W
N
F
D
D
T
E
K
E
P
T
V
L
P
A
A
F
P
N
L
L
V
N
G
S
T
G
I
S
A
G
Y
A
T
D
I
P
P
H
N
L
A
E
V
I
D
A
A
V
Y
M
I
D
H
P
T
A
----
K
----
I
D
K
L
M
E
F
L
P
G
P
D
F
P
T
G
A
I
I
Q
G
R
D
E
I
K
K
A
Y
E
T
G
K
G
R
V
V
V
R
S
K
T
E
I
E
-
K
L
K
G
G
K
E
Q
I
V
I
T
E
I
P
Y
E
I
N
K
A
N
L
V
K
K
I
D
D
V
R
V
N
N
K
V
A
G
I
A
E
V
R
D
E
-
S
D
-
R
-
D
G
L
R
I
A
I
E
L
K
K
D
A
N
T
E
L
V
L
N
Y
L
F
K
Y
T
D
L
Q
I
N
Y
N
F
N
M
V
A
I
D
N
F
T
P
R
Q
V
G
I
V
P
I
L
S
S
Y
I
A
H
R
R
E
V
I
L
A
R
S
R
F
D
K
E
K
A
E
K
R
L
H
I
V
E
G
L
I
R
V
I
S
I
L
D
E
V
I
A
L
I
R
A
S
E
N
K
A
D
A
K
E
N
L
K
V
S
------------------------------
Y
D
F
T
E
E
Q
A
E
A
I
V
T
L
Q
L
Y
R
L
T
N
T
D
V
V
V
L
Q
E
E
E
A
E
L
R
E
K
I
A
M
L
A
A
I
I
G
D
E
R
T
M
Y
N
L
M
K
K
E
L
R
E
V
K
K
K
F
A
T
P
R
L
S
S
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
10
PsiBlast_PDB
91.65
65%
-62
- C2 -
3RAE
4
PARC_STRPN
A:
[3-483]
------
N
I
Q
N
M
S
L
E
D
I
M
G
E
R
F
G
R
Y
S
K
Y
I
I
Q
D
R
A
L
P
D
I
R
D
G
L
K
P
V
Q
R
R
I
L
Y
S
M
N
K
D
S
N
T
F
D
K
S
Y
R
K
S
A
K
S
V
G
N
I
M
G
N
F
H
P
H
G
D
S
S
I
Y
D
A
M
V
R
M
S
Q
N
W
K
N
R
E
I
L
V
E
M
H
G
N
N
G
S
M
D
G
D
P
P
A
A
M
R
Y
T
E
A
R
L
S
E
I
A
G
Y
L
L
Q
D
I
E
K
K
T
V
P
F
A
W
N
F
D
D
T
E
K
E
P
T
V
L
P
A
A
F
P
N
L
L
V
N
G
S
T
G
I
S
A
G
Y
A
T
D
I
P
P
H
N
L
A
E
V
I
D
A
A
V
Y
M
I
D
H
P
T
A
----
K
----
I
D
K
L
M
E
F
L
P
G
P
D
F
P
T
G
A
I
I
Q
G
R
D
E
I
K
K
A
Y
E
T
G
K
G
R
V
V
V
R
S
K
T
E
I
E
-
K
L
K
G
G
K
E
Q
I
V
I
T
E
I
P
Y
E
I
N
K
A
N
L
V
K
K
I
D
D
V
R
V
N
N
K
V
A
G
I
A
E
V
R
D
E
-
S
D
-
R
-
D
G
L
R
I
A
I
E
L
K
K
D
A
N
T
E
L
V
L
N
Y
L
F
K
Y
T
D
L
Q
I
N
Y
N
F
N
M
V
A
I
D
N
F
T
P
R
Q
V
G
I
V
P
I
L
S
S
Y
I
A
H
R
R
E
V
I
L
A
R
S
R
F
D
K
E
K
A
E
K
R
L
H
I
V
E
G
L
I
R
V
I
S
I
L
D
E
V
I
A
L
I
R
A
S
E
N
K
A
D
A
K
E
N
L
K
V
S
------------------------------
Y
D
F
T
E
E
Q
A
E
A
I
V
T
L
Q
L
Y
R
L
T
N
T
D
V
V
V
L
Q
E
E
E
A
E
L
R
E
K
I
A
M
L
A
A
I
I
G
D
E
R
T
M
Y
N
L
M
K
K
E
L
R
E
V
K
K
K
F
A
T
P
R
L
S
S
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
22
PsiBlast_CBE
91.57
65%
-62
- C2 -
4KPE
6
PARC_STRPN
B:
[3-483]
------
N
I
Q
N
M
S
L
E
D
I
M
G
E
R
F
G
R
Y
S
K
Y
I
I
Q
D
R
A
L
P
D
I
R
D
G
L
K
P
V
Q
R
R
I
L
Y
S
M
N
K
D
S
N
T
F
D
K
S
Y
R
K
S
A
K
S
V
G
N
I
M
G
N
F
H
P
H
G
D
S
S
I
Y
D
A
M
V
R
M
S
Q
N
W
K
N
R
E
I
L
V
E
M
H
G
N
N
G
S
M
D
G
D
P
P
A
A
M
R
Y
T
E
A
R
L
S
E
I
A
G
Y
L
L
Q
D
I
E
K
K
T
V
P
F
A
W
N
F
D
D
T
E
K
E
P
T
V
L
P
A
A
F
P
N
L
L
V
N
G
S
T
G
I
S
A
G
Y
A
T
D
I
P
P
H
N
L
A
E
V
I
D
A
A
V
Y
M
I
D
H
P
T
A
----
K
----
I
D
K
L
M
E
F
L
P
G
P
D
F
P
T
G
A
I
I
Q
G
R
D
E
I
K
K
A
Y
E
T
G
K
G
R
V
V
V
R
S
K
T
E
I
E
-
K
L
K
G
G
K
E
Q
I
V
I
T
E
I
P
Y
E
I
N
K
A
N
L
V
K
K
I
D
D
V
R
V
N
N
K
V
A
G
I
A
E
V
R
D
E
-
S
D
-
R
-
D
G
L
R
I
A
I
E
L
K
K
D
A
N
T
E
L
V
L
N
Y
L
F
K
Y
T
D
L
Q
I
N
Y
N
F
N
M
V
A
I
D
N
F
T
P
R
Q
V
G
I
V
P
I
L
S
S
Y
I
A
H
R
R
E
V
I
L
A
R
S
R
F
D
K
E
K
A
E
K
R
L
H
I
V
E
G
L
I
R
V
I
S
I
L
D
E
V
I
A
L
I
R
A
S
E
N
K
A
D
A
K
E
N
L
K
V
S
------------------------------
Y
D
F
T
E
E
Q
A
E
A
I
V
T
L
Q
L
Y
R
L
T
N
T
D
V
V
V
L
Q
E
E
E
A
E
L
R
E
K
I
A
M
L
A
A
I
I
G
D
E
R
T
M
Y
N
L
M
K
K
E
L
R
E
V
K
K
K
F
A
T
P
R
L
S
S
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
26
PsiBlast_CBE
91.56
65%
-64
- C2 -
3RAD
6
PARC_STRPN
B:
[3-483]
------
N
I
Q
N
M
S
L
E
D
I
M
G
E
R
F
G
R
Y
S
K
Y
I
I
Q
D
R
A
L
P
D
I
R
D
G
L
K
P
V
Q
R
R
I
L
Y
S
M
N
K
D
S
N
T
F
D
K
S
Y
R
K
S
A
K
S
V
G
N
I
M
G
N
F
H
P
H
G
D
S
S
I
Y
D
A
M
V
R
M
S
Q
N
W
K
N
R
E
I
L
V
E
M
H
G
N
N
G
S
M
D
G
D
P
P
A
A
M
R
Y
T
E
A
R
L
S
E
I
A
G
Y
L
L
Q
D
I
E
K
K
T
V
P
F
A
W
N
F
D
D
T
E
K
E
P
T
V
L
P
A
A
F
P
N
L
L
V
N
G
S
T
G
I
S
A
G
Y
A
T
D
I
P
P
H
N
L
A
E
V
I
D
A
A
V
Y
M
I
D
H
P
T
A
----
K
----
I
D
K
L
M
E
F
L
P
G
P
D
F
P
T
G
A
I
I
Q
G
R
D
E
I
K
K
A
Y
E
T
G
K
G
R
V
V
V
R
S
K
T
E
I
E
-
K
L
K
G
G
K
E
Q
I
V
I
T
E
I
P
Y
E
I
N
K
A
N
L
V
K
K
I
D
D
V
R
V
N
N
K
V
A
G
I
A
E
V
R
D
E
-
S
D
-
R
-
D
G
L
R
I
A
I
E
L
K
K
D
A
N
T
E
L
V
L
N
Y
L
F
K
Y
T
D
L
Q
I
N
Y
N
F
N
M
V
A
I
D
N
F
T
P
R
Q
V
G
I
V
P
I
L
S
S
Y
I
A
H
R
R
E
V
I
L
A
R
S
R
F
D
K
E
K
A
E
K
R
L
H
I
V
E
G
L
I
R
V
I
S
I
L
D
E
V
I
A
L
I
R
A
S
E
N
K
A
D
A
K
E
N
L
K
V
S
------------------------------
Y
D
F
T
E
E
Q
A
E
A
I
V
T
L
Q
L
Y
R
L
T
N
T
D
V
V
V
L
Q
E
E
E
A
E
L
R
E
K
I
A
M
L
A
A
I
I
G
D
E
R
T
M
Y
N
L
M
K
K
E
L
R
E
V
K
K
K
F
A
T
P
R
L
S
S
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
PsiBlast_CBE
91.36
65%
-63
- C2 -
3RAE
4
PARC_STRPN
B:
[3-483]
------
N
I
Q
N
M
S
L
E
D
I
M
G
E
R
F
G
R
Y
S
K
Y
I
I
Q
D
R
A
L
P
D
I
R
D
G
L
K
P
V
Q
R
R
I
L
Y
S
M
N
K
D
S
N
T
F
D
K
S
Y
R
K
S
A
K
S
V
G
N
I
M
G
N
F
H
P
H
G
D
S
S
I
Y
D
A
M
V
R
M
S
Q
N
W
K
N
R
E
I
L
V
E
M
H
G
N
N
G
S
M
D
G
D
P
P
A
A
M
R
Y
T
E
A
R
L
S
E
I
A
G
Y
L
L
Q
D
I
E
K
K
T
V
P
F
A
W
N
F
D
D
T
E
K
E
P
T
V
L
P
A
A
F
P
N
L
L
V
N
G
S
T
G
I
S
A
G
Y
A
T
D
I
P
P
H
N
L
A
E
V
I
D
A
A
V
Y
M
I
D
H
P
T
A
----
K
----
I
D
K
L
M
E
F
L
P
G
P
D
F
P
T
G
A
I
I
Q
G
R
D
E
I
K
K
A
Y
E
T
G
K
G
R
V
V
V
R
S
K
T
E
I
E
-
K
L
K
G
G
K
E
Q
I
V
I
T
E
I
P
Y
E
I
N
K
A
N
L
V
K
K
I
D
D
V
R
V
N
N
K
V
A
G
I
A
E
V
R
D
E
-
S
D
-
R
-
D
G
L
R
I
A
I
E
L
K
K
D
A
N
T
E
L
V
L
N
Y
L
F
K
Y
T
D
L
Q
I
N
Y
N
F
N
M
V
A
I
D
N
F
T
P
R
Q
V
G
I
V
P
I
L
S
S
Y
I
A
H
R
R
E
V
I
L
A
R
S
R
F
D
K
E
K
A
E
K
R
L
H
I
V
E
G
L
I
R
V
I
S
I
L
D
E
V
I
A
L
I
R
A
S
E
N
K
A
D
A
K
E
N
L
K
V
S
------------------------------
Y
D
F
T
E
E
Q
A
E
A
I
V
T
L
Q
L
Y
R
L
T
N
T
D
V
V
V
L
Q
E
E
E
A
E
L
R
E
K
I
A
M
L
A
A
I
I
G
D
E
R
T
M
Y
N
L
M
K
K
E
L
R
E
V
K
K
K
F
A
T
P
R
L
S
S
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
7
PsiBlast_PDB
91.35
65%
-62
- C2 -
3LTN
4
PARC_STRPN
A:
[3-483]
------
N
I
Q
N
M
S
L
E
D
I
M
G
E
R
F
G
R
Y
S
K
Y
I
I
Q
D
R
A
L
P
D
I
R
D
G
L
K
P
V
Q
R
R
I
L
Y
S
M
N
K
D
S
N
T
F
D
K
S
Y
R
K
S
A
K
S
V
G
N
I
M
G
N
F
H
P
H
G
D
S
S
I
Y
D
A
M
V
R
M
S
Q
N
W
K
N
R
E
I
L
V
E
M
H
G
N
N
G
S
M
D
G
D
P
P
A
A
M
R
Y
T
E
A
R
L
S
E
I
A
G
Y
L
L
Q
D
I
E
K
K
T
V
P
F
A
W
N
F
D
D
T
E
K
E
P
T
V
L
P
A
A
F
P
N
L
L
V
N
G
S
T
G
I
S
A
G
Y
A
T
D
I
P
P
H
N
L
A
E
V
I
D
A
A
V
Y
M
I
D
H
P
T
A
----
K
----
I
D
K
L
M
E
F
L
P
G
P
D
F
P
T
G
A
I
I
Q
G
R
D
E
I
K
K
A
Y
E
T
G
K
G
R
V
V
V
R
S
K
T
E
I
E
-
K
L
K
G
G
K
E
Q
I
V
I
T
E
I
P
Y
E
I
N
K
A
N
L
V
K
K
I
D
D
V
R
V
N
N
K
V
A
G
I
A
E
V
R
D
E
-
S
D
-
R
-
D
G
L
R
I
A
I
E
L
K
K
D
A
N
T
E
L
V
L
N
Y
L
F
K
Y
T
D
L
Q
I
N
Y
N
F
N
M
V
A
I
D
N
F
T
P
R
Q
V
G
I
V
P
I
L
S
S
Y
I
A
H
R
R
E
V
I
L
A
R
S
R
F
D
K
E
K
A
E
K
R
L
H
I
V
E
G
L
I
R
V
I
S
I
L
D
E
V
I
A
L
I
R
A
S
E
N
K
A
D
A
K
E
N
L
K
V
S
------------------------------
Y
D
F
T
E
E
Q
A
E
A
I
V
T
L
Q
L
Y
R
L
T
N
T
D
V
V
V
L
Q
E
E
E
A
E
L
R
E
K
I
A
M
L
A
A
I
I
G
D
E
R
T
M
Y
N
L
M
K
K
E
L
R
E
V
K
K
K
F
A
T
P
R
L
S
S
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
91.34
65%
-65
- C2 -
4KPF
5
PARC_STRPN
B:
[3-483]
------
N
I
Q
N
M
S
L
E
D
I
M
G
E
R
F
G
R
Y
S
K
Y
I
I
Q
D
R
A
L
P
D
I
R
D
G
L
K
P
V
Q
R
R
I
L
Y
S
M
N
K
D
S
N
T
F
D
K
S
Y
R
K
S
A
K
S
V
G
N
I
M
G
N
F
H
P
H
G
D
S
S
I
Y
D
A
M
V
R
M
S
Q
N
W
K
N
R
E
I
L
V
E
M
H
G
N
N
G
S
M
D
G
D
P
P
A
A
M
R
Y
T
E
A
R
L
S
E
I
A
G
Y
L
L
Q
D
I
E
K
K
T
V
P
F
A
W
N
F
D
D
T
E
K
E
P
T
V
L
P
A
A
F
P
N
L
L
V
N
G
S
T
G
I
S
A
G
Y
A
T
D
I
P
P
H
N
L
A
E
V
I
D
A
A
V
Y
M
I
D
H
P
T
A
----
K
----
I
D
K
L
M
E
F
L
P
G
P
D
F
P
T
G
A
I
I
Q
G
R
D
E
I
K
K
A
Y
E
T
G
K
G
R
V
V
V
R
S
K
T
E
I
E
-
K
L
K
G
G
K
E
Q
I
V
I
T
E
I
P
Y
E
I
N
K
A
N
L
V
K
K
I
D
D
V
R
V
N
N
K
V
A
G
I
A
E
V
R
D
E
-
S
D
-
R
-
D
G
L
R
I
A
I
E
L
K
K
D
A
N
T
E
L
V
L
N
Y
L
F
K
Y
T
D
L
Q
I
N
Y
N
F
N
M
V
A
I
D
N
F
T
P
R
Q
V
G
I
V
P
I
L
S
S
Y
I
A
H
R
R
E
V
I
L
A
R
S
R
F
D
K
E
K
A
E
K
R
L
H
I
V
E
G
L
I
R
V
I
S
I
L
D
E
V
I
A
L
I
R
A
S
E
N
K
A
D
A
K
E
N
L
K
V
S
------------------------------
Y
D
F
T
E
E
Q
A
E
A
I
V
T
L
Q
L
Y
R
L
T
N
T
D
V
V
V
L
Q
E
E
E
A
E
L
R
E
K
I
A
M
L
A
A
I
I
G
D
E
R
T
M
Y
N
L
M
K
K
E
L
R
E
V
K
K
K
F
A
T
P
R
L
S
S
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
24
PsiBlast_CBE
91.26
65%
-64
- C2 -
3RAF
5
PARC_STRPN
B:
[3-483]
------
N
I
Q
N
M
S
L
E
D
I
M
G
E
R
F
G
R
Y
S
K
Y
I
I
Q
D
R
A
L
P
D
I
R
D
G
L
K
P
V
Q
R
R
I
L
Y
S
M
N
K
D
S
N
T
F
D
K
S
Y
R
K
S
A
K
S
V
G
N
I
M
G
N
F
H
P
H
G
D
S
S
I
Y
D
A
M
V
R
M
S
Q
N
W
K
N
R
E
I
L
V
E
M
H
G
N
N
G
S
M
D
G
D
P
P
A
A
M
R
Y
T
E
A
R
L
S
E
I
A
G
Y
L
L
Q
D
I
E
K
K
T
V
P
F
A
W
N
F
D
D
T
E
K
E
P
T
V
L
P
A
A
F
P
N
L
L
V
N
G
S
T
G
I
S
A
G
Y
A
T
D
I
P
P
H
N
L
A
E
V
I
D
A
A
V
Y
M
I
D
H
P
T
A
----
K
----
I
D
K
L
M
E
F
L
P
G
P
D
F
P
T
G
A
I
I
Q
G
R
D
E
I
K
K
A
Y
E
T
G
K
G
R
V
V
V
R
S
K
T
E
I
E
-
K
L
K
G
G
K
E
Q
I
V
I
T
E
I
P
Y
E
I
N
K
A
N
L
V
K
K
I
D
D
V
R
V
N
N
K
V
A
G
I
A
E
V
R
D
E
-
S
D
-
R
-
D
G
L
R
I
A
I
E
L
K
K
D
A
N
T
E
L
V
L
N
Y
L
F
K
Y
T
D
L
Q
I
N
Y
N
F
N
M
V
A
I
D
N
F
T
P
R
Q
V
G
I
V
P
I
L
S
S
Y
I
A
H
R
R
E
V
I
L
A
R
S
R
F
D
K
E
K
A
E
K
R
L
H
I
V
E
G
L
I
R
V
I
S
I
L
D
E
V
I
A
L
I
R
A
S
E
N
K
A
D
A
K
E
N
L
K
V
S
------------------------------
Y
D
F
T
E
E
Q
A
E
A
I
V
T
L
Q
L
Y
R
L
T
N
T
D
V
V
V
L
Q
E
E
E
A
E
L
R
E
K
I
A
M
L
A
A
I
I
G
D
E
R
T
M
Y
N
L
M
K
K
E
L
R
E
V
K
K
K
F
A
T
P
R
L
S
S
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
12
PsiBlast_PDB
91.17
65%
-65
- C2 -
4KPE
5
PARC_STRPN
A:
[3-483]
------
N
I
Q
N
M
S
L
E
D
I
M
G
E
R
F
G
R
Y
S
K
Y
I
I
Q
D
R
A
L
P
D
I
R
D
G
L
K
P
V
Q
R
R
I
L
Y
S
M
N
K
D
S
N
T
F
D
K
S
Y
R
K
S
A
K
S
V
G
N
I
M
G
N
F
H
P
H
G
D
S
S
I
Y
D
A
M
V
R
M
S
Q
N
W
K
N
R
E
I
L
V
E
M
H
G
N
N
G
S
M
D
G
D
P
P
A
A
M
R
Y
T
E
A
R
L
S
E
I
A
G
Y
L
L
Q
D
I
E
K
K
T
V
P
F
A
W
N
F
D
D
T
E
K
E
P
T
V
L
P
A
A
F
P
N
L
L
V
N
G
S
T
G
I
S
A
G
Y
A
T
D
I
P
P
H
N
L
A
E
V
I
D
A
A
V
Y
M
I
D
H
P
T
A
----
K
----
I
D
K
L
M
E
F
L
P
G
P
D
F
P
T
G
A
I
I
Q
G
R
D
E
I
K
K
A
Y
E
T
G
K
G
R
V
V
V
R
S
K
T
E
I
E
-
K
L
K
G
G
K
E
Q
I
V
I
T
E
I
P
Y
E
I
N
K
A
N
L
V
K
K
I
D
D
V
R
V
N
N
K
V
A
G
I
A
E
V
R
D
E
-
S
D
-
R
-
D
G
L
R
I
A
I
E
L
K
K
D
A
N
T
E
L
V
L
N
Y
L
F
K
Y
T
D
L
Q
I
N
Y
N
F
N
M
V
A
I
D
N
F
T
P
R
Q
V
G
I
V
P
I
L
S
S
Y
I
A
H
R
R
E
V
I
L
A
R
S
R
F
D
K
E
K
A
E
K
R
L
H
I
V
E
G
L
I
R
V
I
S
I
L
D
E
V
I
A
L
I
R
A
S
E
N
K
A
D
A
K
E
N
L
K
V
S
------------------------------
Y
D
F
T
E
E
Q
A
E
A
I
V
T
L
Q
L
Y
R
L
T
N
T
D
V
V
V
L
Q
E
E
E
A
E
L
R
E
K
I
A
M
L
A
A
I
I
G
D
E
R
T
M
Y
N
L
M
K
K
E
L
R
E
V
K
K
K
F
A
T
P
R
L
S
S
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
91.10
65%
-61
- C2 -
3K9F
4
PARC_STRPN
A:
[3-483]
------
N
I
Q
N
M
S
L
E
D
I
M
G
E
R
F
G
R
Y
S
K
Y
I
I
Q
D
R
A
L
P
D
I
R
D
G
L
K
P
V
Q
R
R
I
L
Y
S
M
N
K
D
S
N
T
F
D
K
S
Y
R
K
S
A
K
S
V
G
N
I
M
G
N
F
H
P
H
G
D
S
S
I
Y
D
A
M
V
R
M
S
Q
N
W
K
N
R
E
I
L
V
E
M
H
G
N
N
G
S
M
D
G
D
P
P
A
A
M
R
Y
T
E
A
R
L
S
E
I
A
G
Y
L
L
Q
D
I
E
K
K
T
V
P
F
A
W
N
F
D
D
T
E
K
E
P
T
V
L
P
A
A
F
P
N
L
L
V
N
G
S
T
G
I
S
A
G
Y
A
T
D
I
P
P
H
N
L
A
E
V
I
D
A
A
V
Y
M
I
D
H
P
T
A
----
K
----
I
D
K
L
M
E
F
L
P
G
P
D
F
P
T
G
A
I
I
Q
G
R
D
E
I
K
K
A
Y
E
T
G
K
G
R
V
V
V
R
S
K
T
E
I
E
-
K
L
K
G
G
K
E
Q
I
V
I
T
E
I
P
Y
E
I
N
K
A
N
L
V
K
K
I
D
D
V
R
V
N
N
K
V
A
G
I
A
E
V
R
D
E
-
S
D
-
R
-
D
G
L
R
I
A
I
E
L
K
K
D
A
N
T
E
L
V
L
N
Y
L
F
K
Y
T
D
L
Q
I
N
Y
N
F
N
M
V
A
I
D
N
F
T
P
R
Q
V
G
I
V
P
I
L
S
S
Y
I
A
H
R
R
E
V
I
L
A
R
S
R
F
D
K
E
K
A
E
K
R
L
H
I
V
E
G
L
I
R
V
I
S
I
L
D
E
V
I
A
L
I
R
A
S
E
N
K
A
D
A
K
E
N
L
K
V
S
------------------------------
Y
D
F
T
E
E
Q
A
E
A
I
V
T
L
Q
L
Y
R
L
T
N
T
D
V
V
V
L
Q
E
E
E
A
E
L
R
E
K
I
A
M
L
A
A
I
I
G
D
E
R
T
M
Y
N
L
M
K
K
E
L
R
E
V
K
K
K
F
A
T
P
R
L
S
S
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
PsiBlast_PDB
91.06
65%
-68
- C2 -
4KPF
5
PARC_STRPN
A:
[3-483]
------
N
I
Q
N
M
S
L
E
D
I
M
G
E
R
F
G
R
Y
S
K
Y
I
I
Q
D
R
A
L
P
D
I
R
D
G
L
K
P
V
Q
R
R
I
L
Y
S
M
N
K
D
S
N
T
F
D
K
S
Y
R
K
S
A
K
S
V
G
N
I
M
G
N
F
H
P
H
G
D
S
S
I
Y
D
A
M
V
R
M
S
Q
N
W
K
N
R
E
I
L
V
E
M
H
G
N
N
G
S
M
D
G
D
P
P
A
A
M
R
Y
T
E
A
R
L
S
E
I
A
G
Y
L
L
Q
D
I
E
K
K
T
V
P
F
A
W
N
F
D
D
T
E
K
E
P
T
V
L
P
A
A
F
P
N
L
L
V
N
G
S
T
G
I
S
A
G
Y
A
T
D
I
P
P
H
N
L
A
E
V
I
D
A
A
V
Y
M
I
D
H
P
T
A
----
K
----
I
D
K
L
M
E
F
L
P
G
P
D
F
P
T
G
A
I
I
Q
G
R
D
E
I
K
K
A
Y
E
T
G
K
G
R
V
V
V
R
S
K
T
E
I
E
-
K
L
K
G
G
K
E
Q
I
V
I
T
E
I
P
Y
E
I
N
K
A
N
L
V
K
K
I
D
D
V
R
V
N
N
K
V
A
G
I
A
E
V
R
D
E
-
S
D
-
R
-
D
G
L
R
I
A
I
E
L
K
K
D
A
N
T
E
L
V
L
N
Y
L
F
K
Y
T
D
L
Q
I
N
Y
N
F
N
M
V
A
I
D
N
F
T
P
R
Q
V
G
I
V
P
I
L
S
S
Y
I
A
H
R
R
E
V
I
L
A
R
S
R
F
D
K
E
K
A
E
K
R
L
H
I
V
E
G
L
I
R
V
I
S
I
L
D
E
V
I
A
L
I
R
A
S
E
N
K
A
D
A
K
E
N
L
K
V
S
------------------------------
Y
D
F
T
E
E
Q
A
E
A
I
V
T
L
Q
L
Y
R
L
T
N
T
D
V
V
V
L
Q
E
E
E
A
E
L
R
E
K
I
A
M
L
A
A
I
I
G
D
E
R
T
M
Y
N
L
M
K
K
E
L
R
E
V
K
K
K
F
A
T
P
R
L
S
S
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
27
PsiBlast_CBE
91.00
65%
-63
- C2 -
3LTN
4
PARC_STRPN
B:
[3-483]
------
N
I
Q
N
M
S
L
E
D
I
M
G
E
R
F
G
R
Y
S
K
Y
I
I
Q
D
R
A
L
P
D
I
R
D
G
L
K
P
V
Q
R
R
I
L
Y
S
M
N
K
D
S
N
T
F
D
K
S
Y
R
K
S
A
K
S
V
G
N
I
M
G
N
F
H
P
H
G
D
S
S
I
Y
D
A
M
V
R
M
S
Q
N
W
K
N
R
E
I
L
V
E
M
H
G
N
N
G
S
M
D
G
D
P
P
A
A
M
R
Y
T
E
A
R
L
S
E
I
A
G
Y
L
L
Q
D
I
E
K
K
T
V
P
F
A
W
N
F
D
D
T
E
K
E
P
T
V
L
P
A
A
F
P
N
L
L
V
N
G
S
T
G
I
S
A
G
Y
A
T
D
I
P
P
H
N
L
A
E
V
I
D
A
A
V
Y
M
I
D
H
P
T
A
----
K
----
I
D
K
L
M
E
F
L
P
G
P
D
F
P
T
G
A
I
I
Q
G
R
D
E
I
K
K
A
Y
E
T
G
K
G
R
V
V
V
R
S
K
T
E
I
E
-
K
L
K
G
G
K
E
Q
I
V
I
T
E
I
P
Y
E
I
N
K
A
N
L
V
K
K
I
D
D
V
R
V
N
N
K
V
A
G
I
A
E
V
R
D
E
-
S
D
-
R
-
D
G
L
R
I
A
I
E
L
K
K
D
A
N
T
E
L
V
L
N
Y
L
F
K
Y
T
D
L
Q
I
N
Y
N
F
N
M
V
A
I
D
N
F
T
P
R
Q
V
G
I
V
P
I
L
S
S
Y
I
A
H
R
R
E
V
I
L
A
R
S
R
F
D
K
E
K
A
E
K
R
L
H
I
V
E
G
L
I
R
V
I
S
I
L
D
E
V
I
A
L
I
R
A
S
E
N
K
A
D
A
K
E
N
L
K
V
S
------------------------------
Y
D
F
T
E
E
Q
A
E
A
I
V
T
L
Q
L
Y
R
L
T
N
T
D
V
V
V
L
Q
E
E
E
A
E
L
R
E
K
I
A
M
L
A
A
I
I
G
D
E
R
T
M
Y
N
L
M
K
K
E
L
R
E
V
K
K
K
F
A
T
P
R
L
S
S
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
23
PsiBlast_CBE
90.95
65%
-63
- C2 -
4KOE
5
PARC_STRPN
B:
[3-483]
------
N
I
Q
N
M
S
L
E
D
I
M
G
E
R
F
G
R
Y
S
K
Y
I
I
Q
D
R
A
L
P
D
I
R
D
G
L
K
P
V
Q
R
R
I
L
Y
S
M
N
K
D
S
N
T
F
D
K
S
Y
R
K
S
A
K
S
V
G
N
I
M
G
N
F
H
P
H
G
D
S
S
I
Y
D
A
M
V
R
M
S
Q
N
W
K
N
R
E
I
L
V
E
M
H
G
N
N
G
S
M
D
G
D
P
P
A
A
M
R
Y
T
E
A
R
L
S
E
I
A
G
Y
L
L
Q
D
I
E
K
K
T
V
P
F
A
W
N
F
D
D
T
E
K
E
P
T
V
L
P
A
A
F
P
N
L
L
V
N
G
S
T
G
I
S
A
G
Y
A
T
D
I
P
P
H
N
L
A
E
V
I
D
A
A
V
Y
M
I
D
H
P
T
A
----
K
----
I
D
K
L
M
E
F
L
P
G
P
D
F
P
T
G
A
I
I
Q
G
R
D
E
I
K
K
A
Y
E
T
G
K
G
R
V
V
V
R
S
K
T
E
I
E
-
K
L
K
G
G
K
E
Q
I
V
I
T
E
I
P
Y
E
I
N
K
A
N
L
V
K
K
I
D
D
V
R
V
N
N
K
V
A
G
I
A
E
V
R
D
E
-
S
D
-
R
-
D
G
L
R
I
A
I
E
L
K
K
D
A
N
T
E
L
V
L
N
Y
L
F
K
Y
T
D
L
Q
I
N
Y
N
F
N
M
V
A
I
D
N
F
T
P
R
Q
V
G
I
V
P
I
L
S
S
Y
I
A
H
R
R
E
V
I
L
A
R
S
R
F
D
K
E
K
A
E
K
R
L
H
I
V
E
G
L
I
R
V
I
S
I
L
D
E
V
I
A
L
I
R
A
S
E
N
K
A
D
A
K
E
N
L
K
V
S
------------------------------
Y
D
F
T
E
E
Q
A
E
A
I
V
T
L
Q
L
Y
R
L
T
N
T
D
V
V
V
L
Q
E
E
E
A
E
L
R
E
K
I
A
M
L
A
A
I
I
G
D
E
R
T
M
Y
N
L
M
K
K
E
L
R
E
V
K
K
K
F
A
T
P
R
L
S
S
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
30
PsiBlast_CBE
90.91
65%
-61
- C2 -
3K9F
4
PARC_STRPN
B:
[3-483]
------
N
I
Q
N
M
S
L
E
D
I
M
G
E
R
F
G
R
Y
S
K
Y
I
I
Q
D
R
A
L
P
D
I
R
D
G
L
K
P
V
Q
R
R
I
L
Y
S
M
N
K
D
S
N
T
F
D
K
S
Y
R
K
S
A
K
S
V
G
N
I
M
G
N
F
H
P
H
G
D
S
S
I
Y
D
A
M
V
R
M
S
Q
N
W
K
N
R
E
I
L
V
E
M
H
G
N
N
G
S
M
D
G
D
P
P
A
A
M
R
Y
T
E
A
R
L
S
E
I
A
G
Y
L
L
Q
D
I
E
K
K
T
V
P
F
A
W
N
F
D
D
T
E
K
E
P
T
V
L
P
A
A
F
P
N
L
L
V
N
G
S
T
G
I
S
A
G
Y
A
T
D
I
P
P
H
N
L
A
E
V
I
D
A
A
V
Y
M
I
D
H
P
T
A
----
K
----
I
D
K
L
M
E
F
L
P
G
P
D
F
P
T
G
A
I
I
Q
G
R
D
E
I
K
K
A
Y
E
T
G
K
G
R
V
V
V
R
S
K
T
E
I
E
-
K
L
K
G
G
K
E
Q
I
V
I
T
E
I
P
Y
E
I
N
K
A
N
L
V
K
K
I
D
D
V
R
V
N
N
K
V
A
G
I
A
E
V
R
D
E
-
S
D
-
R
-
D
G
L
R
I
A
I
E
L
K
K
D
A
N
T
E
L
V
L
N
Y
L
F
K
Y
T
D
L
Q
I
N
Y
N
F
N
M
V
A
I
D
N
F
T
P
R
Q
V
G
I
V
P
I
L
S
S
Y
I
A
H
R
R
E
V
I
L
A
R
S
R
F
D
K
E
K
A
E
K
R
L
H
I
V
E
G
L
I
R
V
I
S
I
L
D
E
V
I
A
L
I
R
A
S
E
N
K
A
D
A
K
E
N
L
K
V
S
------------------------------
Y
D
F
T
E
E
Q
A
E
A
I
V
T
L
Q
L
Y
R
L
T
N
T
D
V
V
V
L
Q
E
E
E
A
E
L
R
E
K
I
A
M
L
A
A
I
I
G
D
E
R
T
M
Y
N
L
M
K
K
E
L
R
E
V
K
K
K
F
A
T
P
R
L
S
S
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
6
PsiBlast_PDB
90.88
65%
-68
- C2 -
3KSB
2
PARC_STRPN
A:
[3-483]
------
N
I
Q
N
M
S
L
E
D
I
M
G
E
R
F
G
R
Y
S
K
Y
I
I
Q
D
R
A
L
P
D
I
R
D
G
L
K
P
V
Q
R
R
I
L
Y
S
M
N
K
D
S
N
T
F
D
K
S
Y
R
K
S
A
K
S
V
G
N
I
M
G
N
F
H
P
H
G
D
S
S
I
Y
D
A
M
V
R
M
S
Q
N
W
K
N
R
E
I
L
V
E
M
H
G
N
N
G
S
M
D
G
D
P
P
A
A
M
R
Y
T
E
A
R
L
S
E
I
A
G
Y
L
L
Q
D
I
E
K
K
T
V
P
F
A
W
N
F
D
D
T
E
K
E
P
T
V
L
P
A
A
F
P
N
L
L
V
N
G
S
T
G
I
S
A
G
Y
A
T
D
I
P
P
H
N
L
A
E
V
I
D
A
A
V
Y
M
I
D
H
P
T
A
----
K
----
I
D
K
L
M
E
F
L
P
G
P
D
F
P
T
G
A
I
I
Q
G
R
D
E
I
K
K
A
Y
E
T
G
K
G
R
V
V
V
R
S
K
T
E
I
E
-
K
------
Q
I
V
I
T
E
I
P
Y
E
I
N
K
A
N
L
V
K
K
I
D
D
V
R
V
N
N
K
V
A
G
I
A
-
V
R
D
E
-
S
D
-
R
-
D
G
L
R
I
A
I
---
K
D
A
N
T
E
L
V
L
N
Y
L
F
K
Y
T
D
L
Q
I
N
Y
N
F
N
M
V
A
I
D
N
F
T
P
R
Q
V
G
I
V
P
I
L
S
S
Y
I
A
H
R
R
E
V
I
L
A
R
S
R
F
D
K
E
K
A
E
K
R
L
H
I
V
E
G
L
I
R
V
I
S
I
L
D
E
V
I
A
L
I
R
A
S
E
N
K
A
D
A
K
E
N
L
K
V
S
------------------------------
Y
D
F
T
E
E
Q
A
E
A
I
V
T
L
Q
L
Y
R
L
T
N
T
D
V
V
V
L
Q
E
E
E
A
E
L
R
E
K
I
A
M
L
A
A
I
I
G
D
E
R
T
M
Y
N
L
M
K
K
E
L
R
E
V
K
K
K
F
A
T
P
R
L
S
S
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
28
PsiBlast_CBE
90.71
65%
-67
- C2 -
3KSB
2
PARC_STRPN
B:
[3-483]
------
N
I
Q
N
M
S
L
E
D
I
M
G
E
R
F
G
R
Y
S
K
Y
I
I
Q
D
R
A
L
P
D
I
R
D
G
L
K
P
V
Q
R
R
I
L
Y
S
M
N
K
D
S
N
T
F
D
K
S
Y
R
K
S
A
K
S
V
G
N
I
M
G
N
F
H
P
H
G
D
S
S
I
Y
D
A
M
V
R
M
S
Q
N
W
K
N
R
E
I
L
V
E
M
H
G
N
N
G
S
M
D
G
D
P
P
A
A
M
R
Y
T
E
A
R
L
S
E
I
A
G
Y
L
L
Q
D
I
E
K
K
T
V
P
F
A
W
N
F
D
D
T
E
K
E
P
T
V
L
P
A
A
F
P
N
L
L
V
N
G
S
T
G
I
S
A
G
Y
A
T
D
I
P
P
H
N
L
A
E
V
I
D
A
A
V
Y
M
I
D
H
P
T
A
----
K
----
I
D
K
L
M
E
F
L
P
G
P
D
F
P
T
G
A
I
I
Q
G
R
D
E
I
K
K
A
Y
E
T
G
K
G
R
V
V
V
R
S
K
T
E
I
E
-
K
------
Q
I
V
I
T
E
I
P
Y
E
I
N
K
A
N
L
V
K
K
I
D
D
V
R
V
N
N
K
V
A
G
I
A
-
V
R
D
E
-
S
D
-
R
-
D
G
L
R
I
A
I
---
K
D
A
N
T
E
L
V
L
N
Y
L
F
K
Y
T
D
L
Q
I
N
Y
N
F
N
M
V
A
I
D
N
F
T
P
R
Q
V
G
I
V
P
I
L
S
S
Y
I
A
H
R
R
E
V
I
L
A
R
S
R
F
D
K
E
K
A
E
K
R
L
H
I
V
E
G
L
I
R
V
I
S
I
L
D
E
V
I
A
L
I
R
A
S
E
N
K
A
D
A
K
E
N
L
K
V
S
------------------------------
Y
D
F
T
E
E
Q
A
E
A
I
V
T
L
Q
L
Y
R
L
T
N
T
D
V
V
V
L
Q
E
E
E
A
E
L
R
E
K
I
A
M
L
A
A
I
I
G
D
E
R
T
M
Y
N
L
M
K
K
E
L
R
E
V
K
K
K
F
A
T
P
R
L
S
S
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
29
PsiBlast_CBE
90.60
65%
-65
- C2 -
3KSA
2
PARC_STRPN
B:
[3-483]
------
N
I
Q
N
M
S
L
E
D
I
M
G
E
R
F
G
R
Y
S
K
Y
I
I
Q
D
R
A
L
P
D
I
R
D
G
L
K
P
V
Q
R
R
I
L
Y
S
M
N
K
D
S
N
T
F
D
K
S
Y
R
K
S
A
K
S
V
G
N
I
M
G
N
F
H
P
H
G
D
S
S
I
Y
D
A
M
V
R
M
S
Q
N
W
K
N
R
E
I
L
V
E
M
H
G
N
N
G
S
M
D
G
D
P
P
A
A
M
R
Y
T
E
A
R
L
S
E
I
A
G
Y
L
L
Q
D
I
E
K
K
T
V
P
F
A
W
N
F
D
D
T
E
K
E
P
T
V
L
P
A
A
F
P
N
L
L
V
N
G
S
T
G
I
S
A
G
Y
A
T
D
I
P
P
H
N
L
A
E
V
I
D
A
A
V
Y
M
I
D
H
P
T
A
----
K
----
I
D
K
L
M
E
F
L
P
G
P
D
F
P
T
G
A
I
I
Q
G
R
D
E
I
K
K
A
Y
E
T
G
K
G
R
V
V
V
R
S
K
T
E
I
E
-
K
------
Q
I
V
I
T
E
I
P
Y
E
I
N
K
A
N
L
V
K
K
I
D
D
V
R
V
N
N
K
V
A
G
I
A
-
V
R
D
E
-
S
D
-
R
-
D
G
L
R
I
A
I
E
L
K
K
D
A
N
T
E
L
V
L
N
Y
L
F
K
Y
T
D
L
Q
I
N
Y
N
F
N
M
V
A
I
D
N
F
T
P
R
Q
V
G
I
V
P
I
L
S
S
Y
I
A
H
R
R
E
V
I
L
A
R
S
R
F
D
K
E
K
A
E
K
R
L
H
I
V
E
G
L
I
R
V
I
S
I
L
D
E
V
I
A
L
I
R
A
S
E
N
K
A
D
A
K
E
N
L
K
V
S
------------------------------
Y
D
F
T
E
E
Q
A
E
A
I
V
T
L
Q
L
Y
R
L
T
N
T
D
V
V
V
L
Q
E
E
E
A
E
L
R
E
K
I
A
M
L
A
A
I
I
G
D
E
R
T
M
Y
N
L
M
K
K
E
L
R
E
V
K
K
K
F
A
T
P
R
L
S
S
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
90.51
65%
-66
- C2 -
3KSA
2
PARC_STRPN
A:
[3-483]
------
N
I
Q
N
M
S
L
E
D
I
M
G
E
R
F
G
R
Y
S
K
Y
I
I
Q
D
R
A
L
P
D
I
R
D
G
L
K
P
V
Q
R
R
I
L
Y
S
M
N
K
D
S
N
T
F
D
K
S
Y
R
K
S
A
K
S
V
G
N
I
M
G
N
F
H
P
H
G
D
S
S
I
Y
D
A
M
V
R
M
S
Q
N
W
K
N
R
E
I
L
V
E
M
H
G
N
N
G
S
M
D
G
D
P
P
A
A
M
R
Y
T
E
A
R
L
S
E
I
A
G
Y
L
L
Q
D
I
E
K
K
T
V
P
F
A
W
N
F
D
D
T
E
K
E
P
T
V
L
P
A
A
F
P
N
L
L
V
N
G
S
T
G
I
S
A
G
Y
A
T
D
I
P
P
H
N
L
A
E
V
I
D
A
A
V
Y
M
I
D
H
P
T
A
----
K
----
I
D
K
L
M
E
F
L
P
G
P
D
F
P
T
G
A
I
I
Q
G
R
D
E
I
K
K
A
Y
E
T
G
K
G
R
V
V
V
R
S
K
T
E
I
E
-
K
------
Q
I
V
I
T
E
I
P
Y
E
I
N
K
A
N
L
V
K
K
I
D
D
V
R
V
N
N
K
V
A
G
I
A
-
V
R
D
E
-
S
D
-
R
-
D
G
L
R
I
A
I
E
L
K
K
D
A
N
T
E
L
V
L
N
Y
L
F
K
Y
T
D
L
Q
I
N
Y
N
F
N
M
V
A
I
D
N
F
T
P
R
Q
V
G
I
V
P
I
L
S
S
Y
I
A
H
R
R
E
V
I
L
A
R
S
R
F
D
K
E
K
A
E
K
R
L
H
I
V
E
G
L
I
R
V
I
S
I
L
D
E
V
I
A
L
I
R
A
S
E
N
K
A
D
A
K
E
N
L
K
V
S
------------------------------
Y
D
F
T
E
E
Q
A
E
A
I
V
T
L
Q
L
Y
R
L
T
N
T
D
V
V
V
L
Q
E
E
E
A
E
L
R
E
K
I
A
M
L
A
A
I
I
G
D
E
R
T
M
Y
N
L
M
K
K
E
L
R
E
V
K
K
K
F
A
T
P
R
L
S
S
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
38
PsiBlast_CBE
84.58
44%
-59
* C2 *
2Y3P
1
GYRA_ECOLI (first)
B:
[12-521]
------------
I
E
E
E
L
K
S
S
Y
L
D
Y
A
M
S
V
I
V
G
R
A
L
P
D
V
R
D
G
L
K
P
V
H
R
R
V
L
Y
A
M
N
V
L
G
N
D
W
N
K
A
Y
K
K
S
A
R
V
V
G
D
V
I
G
K
Y
H
P
H
G
D
S
A
V
Y
D
T
I
V
R
M
A
Q
P
F
S
L
R
Y
M
L
V
D
G
Q
G
N
F
G
S
I
D
G
D
S
A
A
A
M
R
Y
T
E
I
R
L
A
K
I
A
H
E
L
M
A
D
L
E
K
E
T
V
D
F
V
D
N
Y
D
G
T
E
K
I
P
D
V
M
P
T
K
I
P
N
L
L
V
N
G
S
S
G
I
A
V
G
M
A
T
N
I
P
P
H
N
L
T
E
V
I
N
G
C
L
A
Y
I
D
D
E
D
I
----
S
----
I
E
G
L
M
E
H
I
P
G
P
D
F
P
T
A
A
I
I
N
G
R
R
G
I
E
E
A
Y
R
T
G
R
G
K
V
Y
I
R
A
R
A
E
V
E
V
D
A
K
T
G
R
E
T
I
I
V
H
E
I
P
Y
Q
V
N
K
A
R
L
I
E
K
I
A
E
L
V
K
E
K
R
V
E
G
I
S
A
L
R
D
E
-
S
D
-
K
-
D
G
M
R
I
V
I
E
V
K
R
D
A
V
G
E
V
V
L
N
N
L
Y
S
Q
T
Q
L
Q
V
S
F
G
I
N
M
V
A
L
H
H
G
Q
P
K
I
M
N
L
K
D
I
I
A
A
F
V
R
H
R
R
E
V
V
T
R
R
T
I
F
E
L
R
K
A
R
D
R
A
H
I
L
E
A
L
A
V
A
L
A
N
I
D
P
I
I
E
L
I
R
H
A
P
T
P
A
E
A
K
T
A
L
V
A
N
PWQLGNVAAMLEDAARPEWLEPEFGVRDG
L
Y
Y
L
T
E
Q
Q
A
Q
A
I
L
D
L
R
L
Q
K
L
T
G
L
E
H
E
K
L
L
D
E
Y
K
E
L
L
D
Q
I
A
E
L
L
R
I
L
G
S
A
D
R
L
M
E
V
I
R
E
E
L
E
L
V
R
E
Q
F
G
D
K
R
R
T
E
I
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
36
PsiBlast_CBE
84.46
49%
-58
- C2 -
2XCR
3
GYRA_STAAN (first)
D:
[240-724]
---
P
Q
S
R
I
N
E
R
N
I
T
S
E
M
R
E
S
F
L
D
Y
A
M
S
V
I
V
A
R
A
L
P
D
V
R
D
G
L
K
P
V
H
R
R
I
L
Y
G
L
N
E
Q
G
M
T
P
D
K
S
Y
K
K
S
A
R
I
V
G
D
V
M
G
K
Y
H
P
H
G
D
S
S
I
Y
E
A
M
V
R
M
A
Q
D
F
S
Y
R
Y
P
L
V
D
G
Q
G
N
F
G
S
M
D
G
D
G
A
A
A
M
R
F
T
E
A
R
M
T
K
I
T
L
E
L
L
R
D
I
N
K
D
T
I
D
F
I
D
N
Y
D
G
N
E
R
E
P
S
V
L
P
A
R
F
P
N
L
L
A
N
G
A
S
G
I
A
V
G
M
A
T
N
I
P
P
H
N
L
T
E
L
I
N
G
V
L
S
L
S
K
N
P
D
I
----
S
----
I
A
E
L
M
E
D
I
E
G
P
D
F
P
T
A
G
L
I
L
G
K
S
G
I
R
R
A
Y
E
T
G
R
G
S
I
Q
M
R
S
R
A
V
I
E
-
E
R
G
G
G
R
Q
R
I
V
V
T
E
I
P
F
Q
V
N
K
A
R
M
I
E
K
I
A
E
L
V
R
D
K
K
I
D
G
I
T
D
L
R
D
E
-
T
S
L
R
-
T
G
V
R
V
V
I
D
V
R
K
D
A
N
A
S
V
I
L
N
N
L
Y
K
Q
T
P
L
Q
T
S
F
G
V
N
M
I
A
L
V
N
G
R
P
K
L
I
N
L
K
E
A
L
V
H
Y
L
E
H
Q
K
T
V
V
R
R
R
T
Q
Y
N
L
R
K
A
K
D
R
A
H
I
L
E
G
L
R
I
A
L
D
H
I
D
E
I
I
S
T
I
R
E
S
D
T
D
K
V
A
M
E
S
L
Q
Q
R
------------------------------
F
K
L
S
E
K
Q
A
Q
A
I
L
D
M
R
L
R
R
L
T
G
L
E
R
D
K
I
E
A
E
Y
N
E
L
L
N
Y
I
S
E
L
E
T
I
L
A
D
E
E
V
L
L
Q
L
V
R
D
E
L
T
E
I
R
D
R
F
G
D
D
R
R
T
E
I
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
18
PsiBlast_PDB
84.40
44%
-62
- C2 -
2Y3P
1
GYRA_ECOLI (first)
A:
[22-521]
----------------------
D
Y
A
M
S
V
I
V
G
R
A
L
P
D
V
R
D
G
L
K
P
V
H
R
R
V
L
Y
A
M
N
V
L
G
N
D
W
N
K
A
Y
K
K
S
A
R
V
V
G
D
V
I
G
K
Y
H
P
H
G
D
S
A
V
Y
D
T
I
V
R
M
A
Q
P
F
S
L
R
Y
M
L
V
D
G
Q
G
N
F
G
S
I
D
G
D
S
A
A
A
M
R
Y
T
E
I
R
L
A
K
I
A
H
E
L
M
A
D
L
E
K
E
T
V
D
F
V
D
N
Y
D
G
T
E
K
I
P
D
V
M
P
T
K
I
P
N
L
L
V
N
G
S
S
G
I
A
V
G
M
A
T
N
I
P
P
H
N
L
T
E
V
I
N
G
C
L
A
Y
I
D
D
E
D
I
----
S
----
I
E
G
L
M
E
H
I
P
G
P
D
F
P
T
A
A
I
I
N
G
R
R
G
I
E
E
A
Y
R
T
G
R
G
K
V
Y
I
R
A
R
A
E
V
E
V
D
A
K
T
G
R
E
T
I
I
V
H
E
I
P
Y
Q
V
N
K
A
R
L
I
E
K
I
A
E
L
V
K
E
K
R
V
E
G
I
S
A
L
R
D
E
-
S
D
-
K
-
D
G
M
R
I
V
I
E
V
K
R
D
A
V
G
E
V
V
L
N
N
L
Y
S
Q
T
Q
L
Q
V
S
F
G
I
N
M
V
A
L
H
H
G
Q
P
K
I
M
N
L
K
D
I
I
A
A
F
V
R
H
R
R
E
V
V
T
R
R
T
I
F
E
L
R
K
A
R
D
R
A
H
I
L
E
A
L
A
V
A
L
A
N
I
D
P
I
I
E
L
I
R
H
A
P
T
P
A
E
A
K
T
A
L
V
A
N
P
W
Q
LGNVAAMLEDAARPEWLEPEFGVRDG
L
Y
Y
L
T
E
Q
Q
A
Q
A
I
L
D
L
R
L
Q
K
L
T
G
L
E
H
E
K
L
L
D
E
Y
K
E
L
L
D
Q
I
A
E
L
L
R
I
L
G
S
A
D
R
L
M
E
V
I
R
E
E
L
E
L
V
R
E
Q
F
G
D
K
R
R
T
E
I
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
16
PsiBlast_PDB
83.95
49%
-60
- C2 -
2XCR
3
GYRA_STAAN (first)
B:
[240-724]
---
P
Q
S
R
I
N
E
R
N
I
T
S
E
M
R
E
S
F
L
D
Y
A
M
S
V
I
V
A
R
A
L
P
D
V
R
D
G
L
K
P
V
H
R
R
I
L
Y
G
L
N
E
Q
G
M
T
P
D
K
S
Y
K
K
S
A
R
I
V
G
D
V
M
G
K
Y
H
P
H
G
D
S
S
I
Y
E
A
M
V
R
M
A
Q
D
F
S
Y
R
Y
P
L
V
D
G
Q
G
N
F
G
S
M
D
G
D
G
A
A
A
M
R
F
T
E
A
R
M
T
K
I
T
L
E
L
L
R
D
I
N
K
D
T
I
D
F
I
D
N
Y
D
G
N
E
R
E
P
S
V
L
P
A
R
F
P
N
L
L
A
N
G
A
S
G
I
A
V
G
M
A
T
N
I
P
P
H
N
L
T
E
L
I
N
G
V
L
S
L
S
K
N
P
D
I
----
S
----
I
A
E
L
M
E
D
I
E
G
P
D
F
P
T
A
G
L
I
L
G
K
S
G
I
R
R
A
Y
E
T
G
R
G
S
I
Q
M
R
S
R
A
V
I
E
-
E
R
G
G
G
R
Q
R
I
V
V
T
E
I
P
F
Q
V
N
K
A
R
M
I
E
K
I
A
E
L
V
R
D
K
K
I
D
G
I
T
D
L
R
D
E
-
T
S
L
R
-
T
G
V
R
V
V
I
D
V
R
K
D
A
N
A
S
V
I
L
N
N
L
Y
K
Q
T
P
L
Q
T
S
F
G
V
N
M
I
A
L
V
N
G
R
P
K
L
I
N
L
K
E
A
L
V
H
Y
L
E
H
Q
K
T
V
V
R
R
R
T
Q
Y
N
L
R
K
A
K
D
R
A
H
I
L
E
G
L
R
I
A
L
D
H
I
D
E
I
I
S
T
I
R
E
S
D
T
D
K
V
A
M
E
S
L
Q
Q
R
------------------------------
F
K
L
S
E
K
Q
A
Q
A
I
L
D
M
R
L
R
R
L
T
G
L
E
R
D
K
I
E
A
E
Y
N
E
L
L
N
Y
I
S
E
L
E
T
I
L
A
D
E
E
V
L
L
Q
L
V
R
D
E
L
T
E
I
R
D
R
F
G
D
D
R
R
T
E
I
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
34
PsiBlast_CBE
83.42
49%
-61
- C2 -
2XCR
3
GYRA_STAAN (first)
U:
[240-724]
---
P
Q
S
R
I
N
E
R
N
I
T
S
E
M
R
E
S
F
L
D
Y
A
M
S
V
I
V
A
R
A
L
P
D
V
R
D
G
L
K
P
V
H
R
R
I
L
Y
G
L
N
E
Q
G
M
T
P
D
K
S
Y
K
K
S
A
R
I
V
G
D
V
M
G
K
Y
H
P
H
G
D
S
S
I
Y
E
A
M
V
R
M
A
Q
D
F
S
Y
R
Y
P
L
V
D
G
Q
G
N
F
G
S
M
D
G
D
G
A
A
A
M
R
F
T
E
A
R
M
T
K
I
T
L
E
L
L
R
D
I
N
K
D
T
I
D
F
I
D
N
Y
D
G
N
E
R
E
P
S
V
L
P
A
R
F
P
N
L
L
A
N
G
A
S
G
I
A
V
G
M
A
T
N
I
P
P
H
N
L
T
E
L
I
N
G
V
L
S
L
S
K
N
P
D
I
----
S
----
I
A
E
L
M
E
D
I
E
G
P
D
F
P
T
A
G
L
I
L
G
K
S
G
I
R
R
A
Y
E
T
G
R
G
S
I
Q
M
R
S
R
A
V
I
E
-
E
R
G
G
G
R
Q
R
I
V
V
T
E
I
P
F
Q
V
N
K
A
R
M
I
E
K
I
A
E
L
V
R
D
K
K
I
D
G
I
T
D
L
R
D
E
-
T
S
L
R
-
T
G
V
R
V
V
I
D
V
R
K
D
A
N
A
S
V
I
L
N
N
L
Y
K
Q
T
P
L
Q
T
S
F
G
V
N
M
I
A
L
V
N
G
R
P
K
L
I
N
L
K
E
A
L
V
H
Y
L
E
H
Q
K
T
V
V
R
R
R
T
Q
Y
N
L
R
K
A
K
D
R
A
H
I
L
E
G
L
R
I
A
L
D
H
I
D
E
I
I
S
T
I
R
E
S
D
T
D
K
V
A
M
E
S
L
Q
Q
R
------------------------------
F
K
L
S
E
K
Q
A
Q
A
I
L
D
M
R
L
R
R
L
T
G
L
E
R
D
K
I
E
A
E
Y
N
E
L
L
N
Y
I
S
E
L
E
T
I
L
A
D
E
E
V
L
L
Q
L
V
R
D
E
L
T
E
I
R
D
R
F
G
D
D
R
R
T
E
I
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
35
PsiBlast_CBE
83.24
49%
-57
- C2 -
2XCR
3
GYRA_STAAN (first)
S:
[240-724]
---
P
Q
S
R
I
N
E
R
N
I
T
S
E
M
R
E
S
F
L
D
Y
A
M
S
V
I
V
A
R
A
L
P
D
V
R
D
G
L
K
P
V
H
R
R
I
L
Y
G
L
N
E
Q
G
M
T
P
D
K
S
Y
K
K
S
A
R
I
V
G
D
V
M
G
K
Y
H
P
H
G
D
S
S
I
Y
E
A
M
V
R
M
A
Q
D
F
S
Y
R
Y
P
L
V
D
G
Q
G
N
F
G
S
M
D
G
D
G
A
A
A
M
R
F
T
E
A
R
M
T
K
I
T
L
E
L
L
R
D
I
N
K
D
T
I
D
F
I
D
N
Y
D
G
N
E
R
E
P
S
V
L
P
A
R
F
P
N
L
L
A
N
G
A
S
G
I
A
V
G
M
A
T
N
I
P
P
H
N
L
T
E
L
I
N
G
V
L
S
L
S
K
N
P
D
I
----
S
----
I
A
E
L
M
E
D
I
E
G
P
D
F
P
T
A
G
L
I
L
G
K
S
G
I
R
R
A
Y
E
T
G
R
G
S
I
Q
M
R
S
R
A
V
I
E
-
E
R
G
G
G
R
Q
R
I
V
V
T
E
I
P
F
Q
V
N
K
A
R
M
I
E
K
I
A
E
L
V
R
D
K
K
I
D
G
I
T
D
L
R
D
E
-
T
S
L
R
-
T
G
V
R
V
V
I
D
V
R
K
D
A
N
A
S
V
I
L
N
N
L
Y
K
Q
T
P
L
Q
T
S
F
G
V
N
M
I
A
L
V
N
G
R
P
K
L
I
N
L
K
E
A
L
V
H
Y
L
E
H
Q
K
T
V
V
R
R
R
T
Q
Y
N
L
R
K
A
K
D
R
A
H
I
L
E
G
L
R
I
A
L
D
H
I
D
E
I
I
S
T
I
R
E
S
D
T
D
K
V
A
M
E
S
L
Q
Q
R
------------------------------
F
K
L
S
E
K
Q
A
Q
A
I
L
D
M
R
L
R
R
L
T
G
L
E
R
D
K
I
E
A
E
Y
N
E
L
L
N
Y
I
S
E
L
E
T
I
L
A
D
E
E
V
L
L
Q
L
V
R
D
E
L
T
E
I
R
D
R
F
G
D
D
R
R
T
E
I
Q
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
40
PsiBlast_CBE
82.85
45%
-57
- C2 -
3IFZ
2
GYRA_MYCTU
A:
[15-499]
-------
I
E
P
V
D
I
E
Q
E
M
Q
R
S
Y
I
D
Y
A
M
S
V
I
V
G
R
A
L
P
E
V
R
D
G
L
K
P
V
H
R
R
V
L
Y
A
M
F
D
S
G
F
R
P
D
R
S
H
A
K
S
A
R
S
V
A
E
T
M
G
N
Y
H
P
H
G
D
A
S
I
Y
D
S
L
V
R
M
A
Q
P
W
S
L
R
Y
P
L
V
D
G
Q
G
N
F
G
S
P
G
N
D
P
P
A
A
M
R
Y
T
E
A
R
L
T
P
L
A
M
E
M
L
R
E
I
D
E
E
T
V
D
F
I
P
N
Y
D
G
R
V
Q
E
P
T
V
L
P
S
R
F
P
N
L
L
A
N
G
S
G
G
I
A
V
G
M
A
T
N
I
P
P
H
N
L
R
E
L
A
D
A
V
F
W
A
L
E
N
H
D
A
D
E
E
E
T
----
L
A
A
V
M
G
R
V
K
G
P
D
F
P
T
A
G
L
I
V
G
S
Q
G
T
A
D
A
Y
K
T
G
R
G
S
I
R
M
R
G
V
V
E
V
E
-
E
D
S
R
----
L
V
I
T
E
L
P
Y
Q
V
N
H
D
N
F
I
T
S
I
A
E
Q
V
R
D
G
K
L
A
G
I
S
N
I
E
D
Q
S
S
D
-
R
-
V
G
L
R
I
V
I
E
I
K
R
D
A
V
A
K
V
V
I
N
N
L
Y
K
H
T
Q
L
Q
T
S
F
G
A
N
M
L
A
I
V
D
G
V
P
R
T
L
R
L
D
Q
L
I
R
Y
Y
V
D
H
Q
L
D
V
I
V
R
R
T
T
Y
R
L
R
K
A
N
E
R
A
H
I
L
R
G
L
V
K
A
L
D
A
L
D
E
V
I
A
L
I
R
A
S
E
T
V
D
I
A
R
A
G
L
I
E
L
------------------------------
L
D
I
D
E
I
Q
A
Q
A
I
L
D
M
Q
L
R
R
L
A
A
L
E
R
Q
R
I
I
D
D
L
A
K
I
E
A
E
I
A
D
L
E
D
I
L
A
K
P
E
R
Q
R
G
I
V
R
D
E
L
A
E
I
V
D
R
H
G
D
D
R
R
T
R
I
I
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
82.73
65%
-66
- C2 -
3FOF
3
PARC_STRPN
A:
[5-479]
--------
Q
N
M
S
L
E
D
I
M
G
E
R
F
G
R
Y
S
K
Y
I
I
Q
D
R
A
L
P
D
I
R
D
G
L
K
P
V
Q
R
R
I
L
Y
S
M
N
K
D
S
N
--
D
K
S
Y
R
K
S
A
K
S
V
G
N
I
M
G
N
F
H
P
H
G
D
S
S
I
Y
D
A
M
V
R
M
S
Q
N
W
K
N
R
E
I
L
V
E
M
H
G
N
N
G
S
M
D
G
D
P
P
A
A
M
R
Y
T
E
A
R
L
S
E
I
A
G
Y
L
L
Q
D
I
E
K
K
T
V
P
F
A
W
N
F
D
D
T
E
K
E
P
T
V
L
P
A
A
F
P
N
L
L
V
N
----------
T
D
I
P
P
H
N
L
A
E
V
I
D
A
A
V
Y
M
I
D
H
P
T
A
----
K
----
I
D
K
L
M
E
F
L
P
G
P
D
F
P
T
G
A
I
I
Q
G
R
D
E
I
K
K
A
Y
E
T
G
-
G
R
V
V
V
R
S
K
T
E
I
E
-
K
L
K
G
G
K
E
Q
I
V
I
T
E
I
----
N
K
A
N
L
V
K
K
I
D
D
V
R
V
N
N
K
V
---------------------
I
E
L
-----
T
E
L
V
L
N
Y
L
F
K
Y
T
D
L
Q
I
N
Y
N
F
N
M
V
A
I
D
N
F
T
P
R
Q
V
G
I
V
P
I
L
S
S
Y
I
A
H
R
R
E
V
I
L
A
R
S
R
F
D
K
E
K
A
E
K
R
L
H
I
V
E
G
L
I
R
V
I
S
I
L
D
E
V
I
A
L
I
R
A
S
E
N
K
A
D
A
K
E
N
L
K
V
S
------------------------------
Y
D
F
T
E
E
Q
A
E
A
I
V
T
L
Q
L
Y
R
L
T
N
T
D
V
V
V
L
Q
E
E
E
A
E
L
R
E
K
I
A
M
L
A
A
I
I
G
D
E
R
T
M
Y
N
L
M
K
K
E
L
R
E
V
K
K
K
F
A
T
P
R
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
2
PsiBlast_PDB
81.85
65%
-65
- C2 -
3FOE
3
PARC_STRPN
A:
[5-479]
--------
Q
N
M
S
L
E
D
I
M
G
E
R
F
G
R
Y
S
K
Y
I
I
Q
D
R
A
L
P
D
I
R
D
G
L
K
P
V
Q
R
R
I
L
Y
S
M
N
K
D
S
N
--
D
K
S
Y
R
K
S
A
K
S
V
G
N
I
M
G
N
F
H
P
H
G
D
S
S
I
Y
D
A
M
V
R
M
S
Q
N
W
K
N
R
E
I
L
V
E
M
H
G
N
N
G
S
M
D
G
D
P
P
A
A
M
R
Y
T
E
A
R
L
S
E
I
A
G
Y
L
L
Q
D
I
E
K
K
T
V
P
F
A
W
N
F
D
D
T
E
K
E
P
T
V
L
P
A
A
F
P
N
L
L
V
N
----------
T
D
I
P
P
H
N
L
A
E
V
I
D
A
A
V
Y
M
I
D
H
P
T
-----
K
----
I
D
K
L
M
E
F
L
P
G
P
D
F
P
T
--
I
I
Q
G
R
D
E
I
K
K
A
Y
E
T
G
-
G
R
V
V
V
R
S
K
T
E
I
E
-
K
L
K
G
G
K
E
Q
I
V
I
T
E
I
----
N
K
A
N
L
V
K
K
I
D
D
V
R
V
N
N
K
V
---------------------
I
E
L
-----
T
E
L
V
L
N
Y
L
F
K
Y
T
D
L
Q
I
N
Y
N
F
N
M
V
A
I
D
N
F
T
P
R
Q
V
G
I
V
P
I
L
S
S
Y
I
A
H
R
R
E
V
I
L
A
R
S
R
F
D
K
E
K
A
E
K
R
L
H
I
V
E
G
L
I
R
V
I
S
I
L
D
E
V
I
A
L
I
R
A
S
E
N
K
A
D
A
K
E
N
L
K
V
S
------------------------------
Y
D
F
T
E
E
Q
A
E
A
I
V
T
L
Q
L
Y
R
L
T
N
T
D
V
V
V
L
Q
E
E
E
A
E
L
R
E
K
I
A
M
L
A
A
I
I
G
D
E
R
T
M
Y
N
L
M
K
K
E
L
R
E
V
K
K
K
F
A
T
P
R
L
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
39
PsiBlast_CBE
81.55
45%
-55
- C2 -
3IFZ
2
GYRA_MYCTU
B:
[29-500]
---------------------
I
D
Y
A
M
S
V
I
V
G
R
A
L
P
E
V
R
D
G
L
K
P
V
H
R
R
V
L
Y
A
M
F
D
S
G
F
R
P
D
R
S
H
A
K
S
A
R
S
V
A
E
T
M
G
N
Y
H
P
H
G
D
A
S
I
Y
D
S
L
V
R
M
A
Q
P
W
S
L
R
Y
P
L
V
D
G
Q
G
N
F
G
S
P
G
N
D
P
P
A
A
M
R
Y
T
E
A
R
L
T
P
L
A
M
E
M
L
R
E
I
D
E
E
T
V
D
F
I
P
N
Y
D
G
R
V
Q
E
P
T
V
L
P
S
R
F
P
N
L
L
A
N
G
S
G
G
I
A
V
G
M
A
T
N
I
P
P
H
N
L
R
E
L
A
D
A
V
F
W
A
L
E
N
H
D
A
D
E
E
E
T
----
L
A
A
V
M
G
R
V
K
G
P
D
F
P
T
A
G
L
I
V
G
S
Q
G
T
A
D
A
Y
K
T
G
R
G
S
I
R
M
R
G
V
V
E
V
E
-
E
D
S
R
G
R
T
S
L
V
I
T
E
L
P
Y
Q
V
N
H
D
N
F
I
T
S
I
A
E
Q
V
R
D
G
K
L
A
G
I
S
N
I
E
D
Q
S
S
D
-
R
-
V
G
L
R
I
V
I
E
I
K
R
D
A
V
A
K
V
V
I
N
N
L
Y
K
H
T
Q
L
Q
T
S
F
G
A
N
M
L
A
I
V
D
G
V
P
R
T
L
R
L
D
Q
L
I
R
Y
Y
V
D
H
Q
L
D
V
I
V
R
R
T
T
Y
R
L
R
K
A
N
E
R
A
H
I
L
R
G
L
V
K
A
L
D
A
L
D
E
V
I
A
L
I
R
A
S
E
T
V
D
I
A
R
A
G
L
I
E
L
------------------------------
L
D
I
D
E
I
Q
A
Q
A
I
L
D
M
Q
L
R
R
L
A
A
L
E
R
Q
R
I
I
D
D
L
A
K
I
E
A
E
I
A
D
L
E
D
I
L
A
K
P
E
R
Q
R
G
I
V
R
D
E
L
A
E
I
V
D
R
H
G
D
D
R
R
T
R
I
I
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
41
PsiBlast_CBE
81.54
46%
-60
- C2 -
3ILW
4
GYRA_MYCTU
B:
[8-470]
------------------------------
G
R
A
L
P
E
V
R
D
G
L
K
P
V
H
R
R
V
L
Y
A
M
F
D
S
G
F
R
P
D
R
S
H
A
K
S
A
R
S
V
A
E
T
M
G
N
Y
H
P
H
G
D
A
S
I
Y
D
S
L
V
R
M
A
Q
P
W
S
L
R
Y
P
L
V
D
G
Q
G
N
F
G
S
P
G
N
D
P
P
A
A
M
R
Y
T
E
A
R
L
T
P
L
A
M
E
M
L
R
E
I
D
E
E
T
V
D
F
I
P
N
Y
D
G
R
V
Q
E
P
T
V
L
P
S
R
F
P
N
L
L
A
N
G
S
G
G
I
A
V
G
M
A
T
N
I
P
P
H
N
L
R
E
L
A
D
A
V
F
W
A
L
E
N
H
D
A
D
E
E
E
T
----
L
A
A
V
M
G
R
V
K
G
P
D
F
P
T
A
G
L
I
V
G
S
Q
G
T
A
D
A
Y
K
T
G
R
G
S
I
R
M
R
G
V
V
E
V
E
-
E
D
S
R
G
R
T
S
L
V
I
T
E
L
P
Y
Q
V
N
H
D
N
F
I
T
S
I
A
E
Q
V
R
D
G
K
L
A
G
I
S
N
I
E
D
Q
S
S
D
-
R
-
V
G
L
R
I
V
I
E
I
K
R
D
A
V
A
K
V
V
I
N
N
L
Y
K
H
T
Q
L
Q
T
S
F
G
A
N
M
L
A
I
V
D
G
V
P
R
T
L
R
L
D
Q
L
I
R
Y
Y
V
D
H
Q
L
D
V
I
V
R
R
T
T
Y
R
L
R
K
A
N
E
R
A
H
I
L
R
G
L
V
K
A
L
D
A
L
D
E
V
I
A
L
I
R
A
S
E
T
V
D
I
A
R
A
G
L
I
E
L
------------------------------
L
D
I
D
E
I
Q
A
Q
A
I
L
D
M
Q
L
R
R
L
A
A
L
E
R
Q
R
I
I
D
D
L
A
K
I
E
A
E
I
A
D
L
E
D
I
L
A
K
P
E
R
Q
R
G
I
V
R
D
E
L
A
E
I
V
D
R
H
G
D
D
R
R
T
R
I
I
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
42
PsiBlast_CBE
81.00
46%
-59
- C2 -
3ILW
4
GYRA_MYCTU
A:
[7-470]
-----------------------------
V
G
R
A
L
P
E
V
R
D
G
L
K
P
V
H
R
R
V
L
Y
A
M
F
D
S
G
F
R
P
D
R
S
H
A
K
S
A
R
S
V
A
E
T
M
G
N
Y
H
P
H
G
D
A
S
I
Y
D
S
L
V
R
M
A
Q
P
W
S
L
R
Y
P
L
V
D
G
Q
G
N
F
G
S
P
G
N
D
P
P
A
A
M
R
Y
T
E
A
R
L
T
P
L
A
M
E
M
L
R
E
I
D
E
E
T
V
D
F
I
P
N
Y
D
G
R
V
Q
E
P
T
V
L
P
S
R
F
P
N
L
L
A
N
G
S
G
G
I
A
V
G
M
A
T
N
I
P
P
H
N
L
R
E
L
A
D
A
V
F
W
A
L
E
N
H
D
A
D
E
E
E
T
----
L
A
A
V
M
G
R
V
K
G
P
D
F
P
T
A
G
L
I
V
G
S
Q
G
T
A
D
A
Y
K
T
G
R
G
S
I
R
M
R
G
V
V
E
V
E
-
E
D
S
R
G
R
T
S
L
V
I
T
E
L
P
Y
Q
V
N
H
D
N
F
I
T
S
I
A
E
Q
V
R
D
G
K
L
A
G
I
S
N
I
E
D
Q
S
S
D
-
R
-
V
G
L
R
I
V
I
E
I
K
R
D
A
V
A
K
V
V
I
N
N
L
Y
K
H
T
Q
L
Q
T
S
F
G
A
N
M
L
A
I
V
D
G
V
P
R
T
L
R
L
D
Q
L
I
R
Y
Y
V
D
H
Q
L
D
V
I
V
R
R
T
T
Y
R
L
R
K
A
N
E
R
A
H
I
L
R
G
L
V
K
A
L
D
A
L
D
E
V
I
A
L
I
R
A
S
E
T
V
D
I
A
R
A
G
L
I
E
L
------------------------------
L
D
I
D
E
I
Q
A
Q
A
I
L
D
M
Q
L
R
R
L
A
A
L
E
R
Q
R
I
I
D
D
L
A
K
I
E
A
E
I
A
D
L
E
D
I
L
A
K
P
E
R
Q
R
G
I
V
R
D
E
L
A
E
I
V
D
R
H
G
D
D
R
R
T
R
I
I
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
61
HHSearch
80.95
46%
-59
- C2 -
3ILW
4
GYRA_MYCTU
A:
[7-470]
-----------------------------
V
G
R
A
L
P
E
V
R
D
G
L
K
P
V
H
R
R
V
L
Y
A
M
F
D
S
G
F
R
P
D
R
S
H
A
K
S
A
R
S
V
A
E
T
M
G
N
Y
H
P
H
G
D
A
S
I
Y
D
S
L
V
R
M
A
Q
P
W
S
L
R
Y
P
L
V
D
G
Q
G
N
F
G
S
P
G
N
D
P
P
A
A
M
R
Y
T
E
A
R
L
T
P
L
A
M
E
M
L
R
E
I
D
E
E
T
V
D
F
I
P
N
Y
D
G
R
V
Q
E
P
T
V
L
P
S
R
F
P
N
L
L
A
N
G
S
G
G
I
A
V
G
M
A
T
N
I
P
P
H
N
L
R
E
L
A
D
A
V
F
W
A
L
E
N
H
D
A
----
D
E
E
E
T
L
A
A
V
M
G
R
V
K
G
P
D
F
P
T
A
G
L
I
V
G
S
Q
G
T
A
D
A
Y
K
T
G
R
G
S
I
R
M
R
G
V
V
E
V
E
-
E
D
S
R
G
R
T
S
L
V
I
T
E
L
P
Y
Q
V
N
H
D
N
F
I
T
S
I
A
E
Q
V
R
D
G
K
L
A
G
I
S
N
I
E
D
Q
-
S
S
-
D
R
V
G
L
R
I
V
I
E
I
K
R
D
A
V
A
K
V
V
I
N
N
L
Y
K
H
T
Q
L
Q
T
S
F
G
A
N
M
L
A
I
V
D
G
V
P
R
T
L
R
L
D
Q
L
I
R
Y
Y
V
D
H
Q
L
D
V
I
V
R
R
T
T
Y
R
L
R
K
A
N
E
R
A
H
I
L
R
G
L
V
K
A
L
D
A
L
D
E
V
I
A
L
I
R
A
S
E
T
V
D
I
A
R
A
G
L
I
E
L
------------------------------
L
D
I
D
E
I
Q
A
Q
A
I
L
D
M
Q
L
R
R
L
A
A
L
E
R
Q
R
I
I
D
D
L
A
K
I
E
A
E
I
A
D
L
E
D
I
L
A
K
P
E
R
Q
R
G
I
V
R
D
E
L
A
E
I
V
D
R
H
G
D
D
R
R
T
R
I
I
A
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------