@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1315: (2016-03-23 )
MFKKLFRQDENILNSELAEDLPIPRHVAIIMDGNGRWAKKRFLPRIAGHKEGMDVVKRVTRYANAIGIDVLTLYAFSTENWKRPTDEVDFLMKLPVEFFDSFVPELIEENVRVNVMGYRENLPDHTMRAVEKAIADTAHCTGLTLNFALNYGGRSEIITAAKEAMKELELEGKSADDLTEEKLNDHLMSSGLGDPDLLIRTSGELRLSNFMLWQLAYSEFYFTDTHWPDFSKEDFLQAIIEYQNRSRRFGGL
Atome Classification :
(55 SA)
.........10..----......20..--......30........40...-...-..50........60........70........80........90........100.......110-.......120.......130.......140.......150.......160...-....170..----....----.180.......190.----......200.......210.......220.......230.......240.......250
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
F
K
K
L
F
R
Q
D
E
N
I
L
----
N
S
E
L
A
E
DLPI--P
R
H
V
A
I
I
MDGNG
R
W
A
K
K
R
F
L
P
-
R
IA-GHK
E
G
M
D
V
V
K
R
V
T
R
Y
A
N
AIG
I
D
V
L
T
L
Y
A
FSTENWKRP
T
D
E
V
D
F
L
M
KL
P
V
E
F
F
D
S
F
V
P
E
L
I
EEN
V
R
-
V
N
V
M
GYRENL
P
D
H
T
M
R
A
V
E
K
A
I
ADTAHCT
G
L
T
L
N
F
A
LNYGG
R
S
E
I
I
T
A
A
K
E
A
M
-
K
E
L
ELEGKS----AD
D
L
----
T
E
E
K
L
N
D
H
L
M
SSGLG----DP
D
L
L
I
RTSG
E
L
R
L
S
N
F
M
L
W
Q
L
A
Y
S
E
F
Y
F
TDTHWPDF
S
K
E
D
F
L
Q
A
I
I
E
Y
Q
N
R
S
RRFGGL
3
PsiBlast_PDB
93.21
52%
-94
- C8 -
4U82
3
ISPT_STAAN
A:
[19-253]
---------------------
L
D
S
S
N
I
--
P
E
H
I
A
I
I
M
D
G
N
G
R
W
A
K
K
R
K
M
P
-
R
I
K
-
G
H
Y
E
G
M
Q
T
I
K
K
I
T
R
I
A
S
D
I
G
V
K
Y
L
T
L
Y
A
F
S
T
E
N
W
S
R
P
E
S
E
V
N
Y
I
M
N
L
P
V
N
F
L
K
T
F
L
P
E
L
I
E
K
N
V
K
-
V
E
T
I
G
F
T
D
K
L
P
K
S
T
I
E
A
I
N
N
A
K
E
K
T
A
N
N
T
G
L
K
L
I
F
A
I
N
Y
G
G
R
A
E
L
V
H
S
I
K
N
M
F
-
D
E
L
H
Q
Q
G
L
N
----
S
D
I
I
----
D
E
T
Y
I
N
N
H
L
M
T
K
D
Y
P
----
D
P
E
L
L
I
R
T
S
G
E
Q
R
I
S
N
F
L
I
W
Q
V
S
Y
S
E
F
I
F
N
Q
K
L
W
P
D
F
D
E
D
E
L
I
K
C
I
K
I
Y
Q
S
R
Q
R
R
F
G
G
L
2
PsiBlast_PDB
93.08
52%
-93
- C8 -
4H8E
3
ISPT_STAAN
A:
[19-253]
---------------------
L
D
S
S
N
I
--
P
E
H
I
A
I
I
M
D
G
N
G
R
W
A
K
K
R
K
M
P
-
R
I
K
-
G
H
Y
E
G
M
Q
T
I
K
K
I
T
R
I
A
S
D
I
G
V
K
Y
L
T
L
Y
A
F
S
T
E
N
W
S
R
P
E
S
E
V
N
Y
I
M
N
L
P
V
N
F
L
K
T
F
L
P
E
L
I
E
K
N
V
K
-
V
E
T
I
G
F
T
D
K
L
P
K
S
T
I
E
A
I
N
N
A
K
E
K
T
A
N
N
T
G
L
K
L
I
F
A
I
N
Y
G
G
R
A
E
L
V
H
S
I
K
N
M
F
-
D
E
L
H
Q
Q
G
L
N
----
S
D
I
I
----
D
E
T
Y
I
N
N
H
L
M
T
K
D
Y
P
----
D
P
E
L
L
I
R
T
S
G
E
Q
R
I
S
N
F
L
I
W
Q
V
S
Y
S
E
F
I
F
N
Q
K
L
W
P
D
F
D
E
D
E
L
I
K
C
I
K
I
Y
Q
S
R
Q
R
R
F
G
G
L
6
PsiBlast_PDB
92.52
53%
-90
- C8 -
4Q9O
2
ISPT_STRR6
A:
[13-240]
--------------------------
V
--
P
A
H
I
G
I
I
M
D
G
N
G
R
W
A
K
K
R
M
Q
P
-
R
V
F
-
G
H
K
A
G
M
E
A
L
Q
T
V
T
K
A
A
N
K
L
G
V
K
V
I
T
V
Y
A
F
S
T
E
N
W
T
R
P
D
Q
E
V
K
F
I
M
N
L
P
V
E
F
Y
D
N
Y
V
P
E
L
H
A
N
N
V
K
-
I
Q
M
I
G
E
T
D
R
L
P
K
Q
T
F
E
A
L
T
K
A
E
E
L
T
K
N
N
T
G
L
I
L
N
F
A
L
N
Y
G
G
R
A
E
I
T
Q
A
L
K
L
I
S
-
Q
D
V
L
D
A
K
I
N
----
P
G
D
I
----
T
E
E
L
I
G
N
Y
L
F
T
Q
H
L
P
KDLR
D
P
D
L
I
I
R
T
S
G
E
L
R
L
S
N
F
L
P
W
Q
G
A
Y
S
E
L
Y
F
T
D
T
L
W
P
D
F
D
E
A
A
L
Q
E
A
I
L
A
Y
N
R
R
H
------
4
PsiBlast_PDB
92.51
52%
-90
- C8 -
3WYI
2
?
A:
[17-247]
-------------------
E
E
L
D
S
S
N
I
--
P
E
H
I
A
I
I
M
D
G
N
G
R
W
A
K
K
R
K
M
P
-
R
I
K
-
G
H
Y
E
G
M
Q
T
I
K
K
I
T
R
I
A
S
D
I
G
V
K
Y
L
T
L
Y
A
F
S
T
E
N
W
S
R
P
E
S
E
V
N
Y
I
M
N
L
P
V
N
F
L
K
T
F
L
P
E
L
I
E
K
N
V
K
-
V
E
T
I
G
F
T
D
K
L
P
K
S
T
I
E
A
I
N
N
A
K
E
K
T
A
N
N
T
G
L
K
L
I
F
A
I
N
Y
G
G
R
A
E
L
V
H
S
I
K
N
M
F
-
D
E
L
H
Q
Q
G
L
N
----
S
D
I
I
----
D
E
T
Y
I
N
N
H
L
M
T
K
D
Y
P
----
D
P
E
L
L
I
R
T
S
G
E
Q
R
I
S
N
F
L
I
W
Q
V
S
Y
S
E
F
I
F
N
Q
K
L
W
P
D
F
D
E
D
E
L
I
K
C
I
K
I
Y
Q
S
R
Q
------
49
PsiBlast_CBE
92.48
48%
-89
- C8 -
1X08
3
UPPS_ECOLI
A:
[13-240]
------------------------
L
P
A
HG
C
R
H
V
A
I
I
M
A
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
E
N
W
N
R
P
A
Q
E
V
S
A
L
M
E
L
F
V
W
A
L
D
S
E
V
K
S
L
H
R
H
N
V
R
-
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
-
E
K
V
Q
Q
G
N
L
Q
----
P
D
Q
I
----
D
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
----
P
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
E
------
10
PsiBlast_PDB
92.45
48%
-89
- C8 -
1X07
3
UPPS_ECOLI
A:
[10-240]
---------------------
S
E
K
L
P
A
HG
C
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
E
N
W
N
R
P
A
Q
E
V
S
A
L
M
E
L
F
V
W
A
L
D
S
E
V
K
S
L
H
R
H
N
V
R
-
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
-
E
K
V
Q
Q
G
N
L
Q
----
P
D
Q
I
----
D
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
----
P
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
E
------
9
PsiBlast_PDB
92.42
48%
-88
- C8 -
1X06
4
UPPS_ECOLI
A:
[12-240]
-----------------------
K
L
P
A
HG
C
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
E
N
W
N
R
P
A
Q
E
V
S
A
L
M
E
L
F
V
W
A
L
D
S
E
V
K
S
L
H
R
H
N
V
R
-
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
-
E
K
V
Q
Q
G
N
L
Q
----
P
D
Q
I
----
D
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
----
P
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
E
------
12
PsiBlast_PDB
92.13
48%
-85
- C8 -
2E99
3
UPPS_ECOLI
A:
[14-240]
-------------------------
P
A
HG
C
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
E
N
W
N
R
P
A
Q
E
V
S
A
L
M
E
L
F
V
W
A
L
D
S
E
V
K
S
L
H
R
H
N
V
R
-
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
-
E
K
V
Q
Q
G
N
L
Q
----
P
D
Q
I
----
D
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
----
P
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
E
------
22
PsiBlast_CBE
91.86
53%
-92
- C8 -
4Q9O
2
ISPT_STRR6
B:
[13-240]
--------------------------
V
--
P
A
H
I
G
I
I
M
D
G
N
G
R
W
A
K
K
R
M
Q
P
-
R
V
F
-
G
H
K
A
G
M
E
A
L
Q
T
V
T
K
A
A
N
K
L
G
V
K
V
I
T
V
Y
A
F
S
T
E
N
W
T
R
P
D
Q
E
V
K
F
I
M
N
L
P
V
E
F
Y
D
N
Y
V
P
E
L
H
A
N
N
V
K
-
I
Q
M
I
G
E
T
D
R
L
P
K
Q
T
F
E
A
L
T
K
A
E
E
L
T
K
N
N
T
G
L
I
L
N
F
A
L
N
Y
G
G
R
A
E
I
T
Q
A
L
K
L
I
S
-
Q
D
V
L
D
A
K
I
N
----
P
G
D
I
----
T
E
E
L
I
G
N
Y
L
F
T
Q
H
L
P
KDLR
D
P
D
L
I
I
R
T
S
G
E
L
R
L
S
N
F
L
P
W
Q
G
A
Y
S
E
L
Y
F
T
D
T
L
W
P
D
F
D
E
A
A
L
Q
E
A
I
L
A
Y
N
R
R
H
------
48
PsiBlast_CBE
91.33
48%
-87
- C8 -
1X09
3
UPPS_ECOLI
A:
[9-239]
--------------------
L
S
E
K
L
P
A
HG
C
R
H
V
A
I
I
M
A
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
E
N
W
N
R
P
A
Q
E
V
S
A
L
M
E
L
F
V
W
A
L
D
S
E
V
K
S
L
H
R
H
N
V
R
-
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
-
E
K
V
Q
Q
G
N
L
Q
----
P
D
Q
I
----
D
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
----
P
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
-------
5
PsiBlast_PDB
91.09
53%
-91
- C8 -
4Q9M
12
ISPT_STRR6
A:
[13-240]
--------------------------
V
--
P
A
H
I
G
I
I
M
D
G
N
G
R
W
A
K
K
R
M
Q
P
-
R
V
F
-
G
H
K
A
G
M
E
A
L
Q
T
V
T
K
A
A
N
K
L
G
V
K
V
I
T
V
Y
A
F
S
T
E
N
W
T
R
P
D
Q
E
V
K
F
I
M
N
L
P
V
E
F
Y
D
N
Y
V
P
E
L
H
A
N
N
V
K
-
I
Q
M
I
G
E
T
D
R
L
P
K
Q
T
F
E
A
L
T
K
A
E
E
L
T
K
N
N
T
G
L
I
L
N
F
A
L
N
Y
G
G
R
A
E
I
T
Q
A
L
K
L
I
S
-
Q
D
V
L
D
A
K
I
N
----
P
G
D
I
----
T
E
E
L
I
G
N
Y
L
F
T
Q
H
L
P
KDLR
D
P
D
L
I
I
R
T
S
G
E
L
R
L
S
N
F
L
P
W
Q
G
A
Y
S
E
L
Y
F
T
D
T
L
W
P
D
F
D
E
A
A
L
Q
E
A
I
L
A
Y
N
R
R
H
------
23
PsiBlast_CBE
90.95
53%
-91
- C8 -
4Q9M
8
ISPT_STRR6
B:
[13-239]
--------------------------
V
--
P
A
H
I
G
I
I
M
D
G
N
G
R
W
A
K
K
R
M
Q
P
-
R
V
F
-
G
H
K
A
G
M
E
A
L
Q
T
V
T
K
A
A
N
K
L
G
V
K
V
I
T
V
Y
A
F
S
T
E
N
W
T
R
P
D
Q
E
V
K
F
I
M
N
L
P
V
E
F
Y
D
N
Y
V
P
E
L
H
A
N
N
V
K
-
I
Q
M
I
G
E
T
D
R
L
P
K
Q
T
F
E
A
L
T
K
A
E
E
L
T
K
N
N
T
G
L
I
L
N
F
A
L
N
Y
G
G
R
A
E
I
T
Q
A
L
K
L
I
S
-
Q
D
V
L
D
A
K
I
N
----
P
G
D
I
----
T
E
E
L
I
G
N
Y
L
F
T
Q
H
L
P
KDLR
D
P
D
L
I
I
R
T
S
G
E
L
R
L
S
N
F
L
P
W
Q
G
A
Y
S
E
L
Y
F
T
D
T
L
W
P
D
F
D
E
A
A
L
Q
E
A
I
L
A
Y
N
R
R
-------
51
PsiBlast_CBE
90.91
43%
-97
- C8 -
4ONC
1
DPDS_MYCTU
A:
[55-280]
--------------------------
L
--
P
N
H
V
A
I
V
M
D
G
N
G
R
W
A
T
Q
R
G
L
A
-
R
T
E
-
G
H
K
M
G
E
A
V
V
I
D
I
A
C
G
A
I
E
L
G
I
K
W
L
S
L
Y
A
F
S
T
E
N
W
K
R
S
P
E
E
V
R
F
L
M
G
F
N
R
D
V
V
R
R
R
R
D
T
L
K
K
L
G
V
R
-
I
R
W
V
G
S
R
P
R
L
W
R
S
V
I
N
E
L
A
V
A
E
E
M
T
K
S
N
D
V
I
T
I
N
Y
C
V
N
Y
G
G
R
T
E
I
T
E
A
T
R
E
I
A
-
R
E
V
A
A
G
R
L
N
----
P
E
R
I
----
T
E
S
T
I
A
R
H
L
Q
R
P
D
I
P
----
D
V
D
L
F
L
R
T
S
G
E
Q
R
S
S
N
F
M
L
W
Q
A
A
Y
A
E
Y
I
F
Q
D
K
L
W
P
D
Y
D
R
R
D
L
W
A
A
C
E
E
Y
A
S
R
T
R
R
----
8
PsiBlast_PDB
90.49
48%
-87
- C8 -
1V7U
2
UPPS_ECOLI
A:
[13-239]
------------------------
L
P
A
HG
C
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
E
N
W
N
R
P
A
Q
E
V
S
A
L
M
E
L
F
V
W
A
L
D
S
E
V
K
S
L
H
R
H
N
V
R
-
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
-
E
K
V
Q
Q
G
N
L
Q
----
P
D
Q
I
----
D
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
----
P
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
-------
46
PsiBlast_CBE
90.38
48%
-90
- C8 -
1UEH
9
UPPS_ECOLI
B:
[17-241]
---------------------------G-
C
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
E
N
W
N
R
P
A
Q
E
V
S
A
L
M
E
L
F
V
W
A
L
D
S
E
V
K
S
L
H
R
H
N
V
R
-
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
-
E
K
V
Q
Q
G
N
L
Q
----
P
D
Q
I
----
D
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
----
P
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
E
R
-----
35
PsiBlast_CBE
89.51
48%
-95
- C8 -
3WYJ
1
UPPS_ECOLI
A:
[14-240]
-------------------------
P
A
HG
C
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
-----
P
A
Q
E
V
S
A
L
M
E
L
F
V
W
A
L
D
S
E
V
K
S
L
H
R
H
N
V
R
-
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
-
E
K
V
Q
Q
G
N
L
Q
----
P
D
Q
I
----
D
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
----
P
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
E
------
37
PsiBlast_CBE
89.05
48%
-94
- C8 -
3SH0
2
UPPS_ECOLI
B:
[13-240]
------------------------
L
P
A
HG
C
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
------
A
Q
E
V
S
A
L
M
E
L
F
V
W
A
L
D
S
E
V
K
S
L
H
R
H
N
V
R
-
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
-
E
K
V
Q
Q
G
N
L
Q
----
P
D
Q
I
----
D
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
----
P
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
E
------
11
PsiBlast_PDB
88.99
48%
-87
- C8 -
2E98
4
UPPS_ECOLI
A:
[15-240]
--------------------------
A
HG
C
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
E
N
W
N
R
P
A
Q
E
V
S
A
L
M
E
L
F
V
W
A
L
D
S
E
V
K
S
L
H
R
H
N
V
R
-
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
-
E
K
V
Q
Q
G
N
L
Q
----
P
D
Q
I
----
D
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
----
P
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
E
------
70
HHSearch
88.74
54%
-99
- C8 -
1F75
1
UPPS_MICLU
A:
[14-242]
--------------------
N
I
N
A
A
Q
I
--
P
K
H
I
A
I
I
M
D
G
N
G
R
W
A
K
Q
K
K
M
P
-
R
I
K
-
G
H
Y
E
G
M
Q
T
V
R
K
I
T
R
Y
A
S
D
L
G
V
K
Y
L
T
L
Y
A
F
------------
N
Y
L
M
K
L
P
G
D
F
L
N
T
F
L
P
E
L
I
E
K
N
V
K
-
V
E
T
I
G
F
I
D
D
L
P
D
H
T
K
K
A
V
L
E
A
K
E
K
T
K
H
N
T
G
L
T
L
V
F
A
L
N
Y
G
G
R
K
E
I
I
S
A
V
Q
L
I
A
-
E
R
Y
K
S
G
E
I
S
----
L
D
E
I
----
S
E
T
H
F
N
E
Y
L
F
T
A
N
M
P
----
D
P
E
L
L
I
R
T
S
G
E
E
R
L
S
N
F
L
I
W
Q
C
S
Y
S
E
F
V
F
I
D
E
F
W
P
D
F
N
E
E
S
L
A
Q
C
I
S
I
Y
Q
N
R
-------
39
PsiBlast_CBE
88.67
48%
-92
- C8 -
3SGV
3
UPPS_ECOLI
A:
[17-238]
---------------------------G-
C
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
E
N
W
N
R
P
A
Q
E
V
S
A
L
M
E
L
F
V
W
A
L
D
S
E
V
K
S
L
H
R
H
N
V
R
-
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
-
E
K
V
Q
Q
G
N
L
Q
----
P
D
Q
I
----
D
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
----
P
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
--------
18
PsiBlast_PDB
88.59
48%
-94
- C8 -
3SGT
1
UPPS_ECOL6
B:
[13-240]
------------------------
L
P
A
HG
C
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
E
N
---
P
A
Q
E
V
S
A
L
M
E
L
F
V
W
A
L
D
S
E
V
K
S
L
H
R
H
N
V
R
-
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
-
E
K
V
Q
Q
G
N
L
Q
----
P
D
Q
I
----
D
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
----
P
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
E
------
34
PsiBlast_CBE
88.01
48%
-91
- C8 -
4H2J
1
UPPS_ECOLI
A:
[13-240]
------------------------
L
P
A
HG
C
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
E
-----------
L
M
E
L
F
V
W
A
L
D
S
E
V
K
S
L
H
R
H
N
V
R
-
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
-
E
K
V
Q
Q
G
N
L
Q
----
P
D
Q
I
----
D
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
----
P
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
E
------
15
PsiBlast_PDB
87.52
48%
-94
- C8 -
2E9D
2
UPPS_ECOLI
A:
[16-240]
---------------------------HG
C
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
-------
A
Q
E
V
S
A
L
M
E
L
F
V
W
A
L
D
S
E
V
K
S
L
H
R
H
N
V
R
-
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
-
E
K
V
Q
Q
G
N
L
Q
----
P
D
Q
I
----
D
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
----
P
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
E
------
42
PsiBlast_CBE
87.21
48%
-95
- C8 -
2E9A
1
UPPS_ECOLI
B:
[17-242]
---------------------------G-
C
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
------------
A
L
M
E
L
F
V
W
A
L
D
S
E
V
K
S
L
H
R
H
N
V
R
-
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
-
E
K
V
Q
Q
G
N
L
Q
----
P
D
Q
I
----
D
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
----
P
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
E
R
R
----
59
PsiBlast_CBE
87.13
43%
-94
- C8 -
2VG2
9
DPDS_MYCTU
A:
[55-282]
--------------------------
L
--
P
N
H
V
A
I
V
M
D
G
N
G
R
W
A
T
Q
R
G
L
A
-
R
T
E
-
G
H
K
M
G
E
A
V
V
I
D
I
A
C
G
A
I
E
L
G
I
K
W
L
S
L
Y
A
F
S
T
E
N
W
K
R
S
P
E
E
V
R
F
L
M
G
F
N
R
D
V
V
R
R
R
R
D
T
L
K
K
L
G
V
R
-
I
R
W
V
G
S
R
P
R
L
W
R
S
V
I
N
E
L
A
V
A
E
E
M
T
K
S
N
D
V
I
T
I
N
Y
C
V
N
Y
G
G
R
T
E
I
T
E
A
T
R
E
I
A
-
R
E
V
A
A
G
R
L
N
----
P
E
R
I
----
T
E
S
T
I
A
R
H
L
Q
R
P
D
I
P
----
D
V
D
L
F
L
R
T
S
G
E
Q
R
S
S
N
F
M
L
W
Q
A
A
Y
A
E
Y
I
F
Q
D
K
L
W
P
D
Y
D
R
R
D
L
W
A
A
C
E
E
Y
A
S
R
T
R
R
F
G
--
33
PsiBlast_CBE
87.12
48%
-93
- C8 -
4H2J
1
UPPS_ECOLI
B:
[17-239]
---------------------------G-
C
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
------------
L
M
E
L
F
V
W
A
L
D
S
E
V
K
S
L
H
R
H
N
V
R
-
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
-
E
K
V
Q
Q
G
N
L
Q
----
P
D
Q
I
----
D
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
----
P
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
-------
50
PsiBlast_CBE
86.69
43%
-98
- C8 -
4ONC
2
DPDS_MYCTU
B:
[55-282]
--------------------------
L
--
P
N
H
V
A
I
V
M
D
G
N
G
R
W
A
T
Q
R
G
L
A
-
R
T
E
-
G
H
K
M
G
E
A
V
V
I
D
I
A
C
G
A
I
E
L
G
I
K
W
L
S
L
Y
A
F
S
T
E
N
W
K
R
S
P
E
E
V
R
F
L
M
G
F
N
R
D
V
V
R
R
R
R
D
T
L
K
K
L
G
V
R
-
I
R
W
V
G
S
R
P
R
L
W
R
S
V
I
N
E
L
A
V
A
E
E
M
T
K
S
N
D
V
I
T
I
N
Y
C
V
N
Y
G
G
R
T
E
I
T
E
A
T
R
E
I
A
-
R
E
V
A
A
G
R
L
N
----
P
E
R
I
----
T
E
S
T
I
A
R
H
L
Q
R
P
D
I
P
----
D
V
D
L
F
L
R
T
S
G
E
Q
R
S
S
N
F
M
L
W
Q
A
A
Y
A
E
Y
I
F
Q
D
K
L
W
P
D
Y
D
R
R
D
L
W
A
A
C
E
E
Y
A
S
R
T
R
R
F
G
--
44
PsiBlast_CBE
86.52
48%
-91
- C8 -
2E98
3
UPPS_ECOLI
B:
[17-243]
---------------------------G-
C
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
----------
S
A
L
M
E
L
F
V
W
A
L
D
S
E
V
K
S
L
H
R
H
N
V
R
-
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
-
E
K
V
Q
Q
G
N
L
Q
----
P
D
Q
I
----
D
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
----
P
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
E
R
R
F
---
20
PsiBlast_PDB
86.52
48%
-97
- C8 -
3SGX
2
UPPS_ECOLI
A:
[17-238]
---------------------------G-
C
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
E
-----------
L
M
E
L
F
V
W
A
L
D
S
E
V
K
S
L
H
R
H
N
V
R
-
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
-
E
K
V
Q
Q
G
N
L
Q
----
P
D
Q
I
----
D
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
----
P
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
--------
13
PsiBlast_PDB
86.47
48%
-92
- C8 -
2E9A
2
UPPS_ECOLI
A:
[14-240]
-------------------------
P
A
HG
C
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
---------
V
S
A
L
M
E
L
F
V
W
A
L
D
S
E
V
K
S
L
H
R
H
N
V
R
-
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
-
E
K
V
Q
Q
G
N
L
Q
----
P
D
Q
I
----
D
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
----
P
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
E
------
57
PsiBlast_CBE
86.46
43%
-96
- C8 -
2VG2
8
DPDS_MYCTU
C:
[55-282]
--------------------------
L
--
P
N
H
V
A
I
V
M
D
G
N
G
R
W
A
T
Q
R
G
L
A
-
R
T
E
-
G
H
K
M
G
E
A
V
V
I
D
I
A
C
G
A
I
E
L
G
I
K
W
L
S
L
Y
A
F
S
T
E
N
W
K
R
S
P
E
E
V
R
F
L
M
G
F
N
R
D
V
V
R
R
R
R
D
T
L
K
K
L
G
V
R
-
I
R
W
V
G
S
R
P
R
L
W
R
S
V
I
N
E
L
A
V
A
E
E
M
T
K
S
N
D
V
I
T
I
N
Y
C
V
N
Y
G
G
R
T
E
I
T
E
A
T
R
E
I
A
-
R
E
V
A
A
G
R
L
N
----
P
E
R
I
----
T
E
S
T
I
A
R
H
L
Q
R
P
D
I
P
----
D
V
D
L
F
L
R
T
S
G
E
Q
R
S
S
N
F
M
L
W
Q
A
A
Y
A
E
Y
I
F
Q
D
K
L
W
P
D
Y
D
R
R
D
L
W
A
A
C
E
E
Y
A
S
R
T
R
R
F
G
--
32
PsiBlast_CBE
86.46
48%
-94
- C8 -
4H2M
1
UPPS_ECOLI
A:
[15-240]
--------------------------
A
HG
C
R
H
V
A
I
I
M
D
G
N
G
R
W
A
K
K
Q
G
K
I
-
R
A
F
-
G
H
K
A
G
A
K
S
V
R
R
A
V
S
F
A
A
N
N
G
I
E
A
L
T
L
Y
A
F
S
S
------------
L
M
E
L
F
V
W
A
L
D
S
E
V
K
S
L
H
R
H
N
V
R
-
L
R
I
I
G
D
T
S
R
F
N
S
R
L
Q
E
R
I
R
K
S
E
A
L
T
A
G
N
T
G
L
T
L
N
I
A
A
N
Y
G
G
R
W
D
I
V
Q
G
V
R
Q
L
A
-
E
K
V
Q
Q
G
N
L
Q
----
P
D
Q
I
----
D
E
E
M
L
N
Q
H
V
C
M
H
E
L
A
----
P
V
D
L
V
I
R
T
G
G
E
H
R
I
S
N
F
L
L
W
Q
I
A
Y
A
E
L
Y
F
T
D
V
L
W
P
D
F
D
E
Q
D
F
E
G
A
L
N
A
F
A
N
R
E
------
54
PsiBlast_CBE
86.41
43%
-97
- C8 -
2VG3
7
DPDS_MYCTU
B:
[55-282]
--------------------------
L
--
P
N
H
V
A
I
V
M
D
G
N
G
R
W
A
T
Q
R
G
L
A
-
R
T
E
-
G
H
K
M
G
E
A
V
V
I
D
I
A
C
G
A
I
E
L
G
I
K
W
L
S
L
Y
A
F
S
T
E
N
W
K
R
S
P
E
E
V
R
F
L
M
G
F
N
R
D
V
V
R
R
R
R
D
T
L
K
K
L
G
V
R
-
I
R
W
V
G
S
R
P
R
L
W
R
S
V
I
N
E
L
A
V
A
E
E
M
T
K
S
N
D
V
I
T
I
N
Y
C
V
N
Y
G
G
R
T
E
I
T
E
A
T
R
E
I
A
-
R
E
V
A
A
G
R
L
N
----
P
E
R
I
----
T
E
S
T
I
A
R
H
L
Q
R
P
D
I
P
----
D
V
D
L
F
L
R
T
S
G
E
Q
R
S
S
N
F
M
L
W
Q
A
A
Y
A
E
Y
I
F
Q
D
K
L
W
P
D
Y
D
R
R
D
L
W
A
A
C
E
E
Y
A
S
R
T
R
R
F
G
--
56
PsiBlast_CBE
86.40
43%
-101
- C8 -
2VG2
5
DPDS_MYCTU
D:
[55-282]
--------------------------
L
--
P
N
H
V
A
I
V
M
D
G
N
G
R
W
A
T
Q
R
G
L
A
-
R
T
E
-
G
H
K
M
G
E
A
V
V
I
D
I
A
C
G
A
I
E
L
G
I
K
W
L
S
L
Y
A
F
S
T
E
N
W
K
R
S
P
E
E
V
R
F
L
M
G
F
N
R
D
V
V
R
R
R
R
D
T
L
K
K
L
G
V
R
-
I
R
W
V
G
S
R
P
R
L
W
R
S
V
I
N
E
L
A
V
A
E
E
M
T
K
S
N
D
V
I
T
I
N
Y
C
V
N
Y
G
G
R
T
E
I
T
E
A
T
R
E
I
A
-
R
E
V
A
A
G
R
L
N
----
P
E
R
I
----
T
E
S
T
I
A
R
H
L
Q
R
P
D
I
P
----
D
V
D
L
F
L
R
T
S
G
E
Q
R
S
S
N
F
M
L
W
Q
A
A
Y
A
E
Y
I
F
Q
D
K
L
W
P
D
Y
D
R
R
D
L
W
A
A
C
E
E
Y
A
S
R
T
R
R
F
G
--