@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1383: (2016-03-24 )
MQKNDDLLRERRKDEHVALGVKQNEQLAPSSLKDIQLIGTSIPRYNVKDIDLTTTIFGKNVPFPFYINAMTGGSRHTKKINAELAEIAREVAIPMAVGSQSAALKNSSLIDTYNIVREINPNGMILANVSPEVAIQDGLQAIEMLEANALQIHINPAQELVMQEGDRSFSHWLTRIEEYVKLSPVPIVVKEVGFGMTRETVKTLADIGVQTVDLAGKGGTNFAQIENDRRRDQAYDFLLDWGISTGQALIDMQHQDAPKIAYLASGGIRNPLDIIKALALGADSVGMAGQIIYSLKKEGVTKTIEKLELWKEQLRGLFVLANAKNIAELKTTPLIVSGELAKWGTLREINLVKLANRK
Atome Classification :
(26 SA)
.........10........20......-..30--........40........50........60........70..-.-.....80........90........100.......110.......120.......130--....----.....140--.........150.......160.......170........180.--......190.......200.......210.......220....--...230----...-.....240.......250.......260.......270.......280.......290...--....300.......310.......320.......330.......340.......350......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MQK
N
D
D
L
L
R
E
R
RKDE
H
V
A
L
GVKQNEQL-APSS--L
K
D
I
Q
L
IGTSIPRYNVKD
I
D
L
T
T
T
IFGKNVPF
P
F
Y
I
N
AMTGG-S-R
H
T
K
K
I
N
A
E
L
A
E
I
A
R
EVAI
P
M
AVGSQSAALKNSS
L
I
D
T
Y
N
I
V
R
EINPN
G
M
I
L
ANVS----
P
E
V
A
----
I
Q
D
G
L
Q
----
A
I
E
M
LEA
N
A
L
Q
I
H
IN
P
A
Q
E
L
V
M
QEGD
R
S
F
S
-
H
W
L
T
R
I
E
E
Y
V
KLS--PV
P
I
V
V
KEVGFG
M
T
R
E
T
V
K
T
L
A
DIG
V
Q
T
V
D
LAGKGGTN
F
A
Q
IE--NDR
R
R
-----
D
Q
A
-
Y
D
F
L
L
DWGIST
G
Q
A
L
I
DMQHQDAP
K
I
A
Y
L
ASGGIR
N
P
L
D
I
I
K
A
L
ALGADSVG
M
A
G
Q
I
I
Y
S
L
--
K
KE
G
V
T
K
T
I
E
K
L
E
L
W
K
E
Q
LR
G
L
F
V
L
ANAK
N
I
A
ELKTT
P
L
I
VSGELAKWGT
L
R
E
I
N
L
V
KLANRK
22
PsiBlast_CBE
94.93
41%
-97
- C3 -
1P0K
1
IDI2_BACSU
B:
[22-349]
-------------------------
E
----
T
G
--
L
D
D
I
T
F
V
H
V
S
L
P
D
L
A
L
E
Q
V
D
I
S
T
K
I
G
E
L
S
S
S
S
P
I
F
I
N
A
M
T
G
G
-
G
G
K
L
T
Y
E
I
N
K
S
L
A
R
A
A
S
Q
A
G
I
P
L
A
V
G
S
Q
M
S
A
L
K
D
P
S
E
R
L
S
Y
E
I
V
R
K
E
N
P
N
G
L
I
F
A
N
L
G
----
S
E
A
T
----
A
A
Q
A
K
E
----
A
V
E
M
I
G
A
N
A
L
Q
I
H
L
N
V
I
Q
E
I
V
M
----
R
S
F
S
-
G
A
L
K
R
I
E
Q
I
C
S
R
V
--
S
V
P
V
I
V
K
E
V
G
F
G
M
S
K
A
S
A
G
K
L
Y
E
A
G
A
A
A
V
D
I
G
G
----------------------
R
Q
--
I
S
F
F
N
S
W
G
I
S
T
A
A
S
L
A
E
I
R
-
S
E
F
P
A
S
T
M
I
A
S
G
G
L
Q
D
A
L
D
V
A
K
A
I
A
L
G
A
S
C
T
G
M
A
G
H
F
L
K
A
L
--
T
D
S
G
E
E
G
L
L
E
E
I
Q
L
I
L
E
E
L
K
L
I
M
T
V
L
G
A
R
T
I
A
D
L
Q
K
A
P
L
V
I
K
G
E
T
H
H
W
L
T
E
R
G
V
N
T
S
S
Y
S
V
R
-
56
PsiBlast_CBE
94.71
35%
-89
- C3 -
2ZRU
1
IDI2_SULSH
B:
[9-358]
-------------
V
E
H
V
E
I
A
A
F
E
N
V
D
G
-
L
S
S
S
TF
L
N
D
V
I
L
V
H
Q
G
F
P
G
I
S
F
S
E
I
N
T
K
T
K
F
F
R
K
E
I
S
V
P
V
M
V
T
G
M
T
-----
N
E
L
G
R
I
N
K
I
I
A
E
V
A
E
K
F
G
I
P
M
G
V
G
S
Q
R
V
A
I
E
K
A
E
A
R
E
S
F
A
I
V
R
K
V
A
P
T
I
P
I
I
A
N
L
G
M---
P
Q
L
V
----
K
G
Y
G
L
K
EFQD
A
I
Q
M
I
E
A
D
A
I
A
V
H
L
N
P
A
Q
E
V
F
Q
P
E
G
E
P
E
Y
Q
I
Y
A
L
E
K
L
R
D
I
S
K
E
L
--
S
V
P
I
I
V
K
E
S
G
N
G
I
S
M
E
T
A
K
L
L
Y
S
Y
G
I
K
N
F
D
T
S
G
Q
G
G
T
N
W
I
A
I
E
MI
R
D
I
R
R
GNWKA
E
S
A
-
K
N
F
-
L
D
W
G
V
P
T
A
A
S
I
M
E
V
R
Y
-
S
V
P
D
S
F
L
V
G
S
G
G
I
R
S
G
L
D
A
A
K
A
I
A
L
G
A
D
I
A
G
M
A
L
P
V
L
K
S
A
IE
G
K
E
S
L
E
Q
F
F
R
K
I
I
F
---
E
L
K
A
A
M
M
L
T
G
S
K
D
V
D
A
L
K
K
T
S
I
V
I
L
G
K
L
K
E
W
A
E
Y
R
G
I
N
L
-------
1
PsiBlast_PDB
94.41
41%
-97
- C3 -
1P0K
1
IDI2_BACSU
A:
[21-349]
------------------------
R
E
----
T
G
--
L
D
D
I
T
F
V
H
V
S
L
P
D
L
A
L
E
Q
V
D
I
S
T
K
I
G
E
L
S
S
S
S
P
I
F
I
N
A
M
T
G
G
-
G
G
K
L
T
Y
E
I
N
K
S
L
A
R
A
A
S
Q
A
G
I
P
L
A
V
G
S
Q
M
S
A
L
K
D
P
S
E
R
L
S
Y
E
I
V
R
K
E
N
P
N
G
L
I
F
A
N
L
G
----
S
E
A
T
----
A
A
Q
A
K
E
----
A
V
E
M
I
G
A
N
A
L
Q
I
H
L
N
V
I
Q
E
I
--------
F
S
-
G
A
L
K
R
I
E
Q
I
C
S
R
V
--
S
V
P
V
I
V
K
E
V
G
F
G
M
S
K
A
S
A
G
K
L
Y
E
A
G
A
A
A
V
D
I
G
G
----------------------
R
Q
--
I
S
F
F
N
S
W
G
I
S
T
A
A
S
L
A
E
I
R
-
S
E
F
P
A
S
T
M
I
A
S
G
G
L
Q
D
A
L
D
V
A
K
A
I
A
L
G
A
S
C
T
G
M
A
G
H
F
L
K
A
L
--
T
D
S
G
E
E
G
L
L
E
E
I
Q
L
I
L
E
E
L
K
L
I
M
T
V
L
G
A
R
T
I
A
D
L
Q
K
A
P
L
V
I
K
G
E
T
H
H
W
L
T
E
R
G
V
N
T
S
S
Y
S
V
R
-
4
PsiBlast_PDB
94.40
35%
-87
- C3 -
2ZRU
1
IDI2_SULSH
A:
[9-358]
-------------
V
E
H
V
E
I
A
A
F
E
N
V
D
G
-
L
S
S
S
TF
L
N
D
V
I
L
V
H
Q
G
F
P
G
I
S
F
S
E
I
N
T
K
T
K
F
F
R
K
E
I
S
V
P
V
M
V
T
G
M
T
-----
N
E
L
G
R
I
N
K
I
I
A
E
V
A
E
K
F
G
I
P
M
G
V
G
S
Q
R
V
A
I
E
K
A
E
A
R
E
S
F
A
I
V
R
K
V
A
P
T
I
P
I
I
A
N
L
G
M
---
P
Q
L
V
----
K
G
Y
G
L
K
E
F
Q
D
A
I
Q
M
I
E
A
D
A
I
A
V
H
L
N
P
A
Q
E
V
F
Q
P
E
G
E
P
E
Y
Q
I
Y
A
L
E
K
L
R
D
I
S
K
E
L
--
S
V
P
I
I
V
K
E
S
G
N
G
I
S
M
E
T
A
K
L
L
Y
S
Y
G
I
K
N
F
D
T
S
G
Q
G
G
T
N
W
I
A
I
E
M
I
R
D
I
R
R
GNWK
A
E
S
A
-
K
N
F
-
L
D
W
G
V
P
T
A
A
S
I
M
E
V
R
Y
-
S
V
P
D
S
F
L
V
G
S
G
G
I
R
S
G
L
D
A
A
K
A
I
A
L
G
A
D
I
A
G
M
A
L
P
V
L
K
S
A
I
E
G
K
E
S
L
E
Q
F
F
R
K
I
I
F
---
E
L
K
A
A
M
M
L
T
G
S
K
D
V
D
A
L
K
K
T
S
I
V
I
L
G
K
L
K
E
W
A
E
Y
R
G
I
N
L
-------
54
PsiBlast_CBE
94.25
35%
-88
- C3 -
2ZRU
1
IDI2_SULSH
D:
[9-358]
-------------
V
E
H
V
E
I
A
A
F
E
N
V
D
G
-
L
S
S
S
TF
L
N
D
V
I
L
V
H
Q
G
F
P
G
I
S
F
S
E
I
N
T
K
T
K
F
F
R
K
E
I
S
V
P
V
M
V
T
G
M
T
-----
N
E
L
G
R
I
N
K
I
I
A
E
V
A
E
K
F
G
I
P
M
G
V
G
S
Q
R
V
A
I
E
K
A
E
A
R
E
S
F
A
I
V
R
K
V
A
P
T
I
P
I
I
A
N
L
G
M---
P
Q
L
V
----
K
G
Y
G
L
K
EFQD
A
I
Q
M
I
E
A
D
A
I
A
V
H
L
N
P
A
Q
E
V
F
Q
P
E
G
E
P
E
Y
Q
I
Y
A
L
E
K
L
R
D
I
S
K
E
L
--
S
V
P
I
I
V
K
E
S
G
N
G
I
S
M
E
T
A
K
L
L
Y
S
Y
G
I
K
N
F
D
T
S
G
Q
G
G
T
N
W
I
A
I
E
MI
R
D
I
R
R
GNWKA
E
S
A
-
K
N
F
-
L
D
W
G
V
P
T
A
A
S
I
M
E
V
R
Y
-
S
V
P
D
S
F
L
V
G
S
G
G
I
R
S
G
L
D
A
A
K
A
I
A
L
G
A
D
I
A
G
M
A
L
P
V
L
K
S
A
IE
G
K
E
S
L
E
Q
F
F
R
K
I
I
F
---
E
L
K
A
A
M
M
L
T
G
S
K
D
V
D
A
L
K
K
T
S
I
V
I
L
G
K
L
K
E
W
A
E
Y
R
G
I
N
L
-------
26
PsiBlast_CBE
94.18
35%
-81
- C3 -
3VKJ
1
IDI2_SULSH
B:
[7-358]
-----------
R
K
V
E
H
V
E
I
A
A
F
E
N
V
D
G
-
L
S
S
S
TF
L
N
D
V
I
L
V
H
Q
G
F
P
G
I
S
F
S
E
I
N
T
K
T
K
F
F
R
K
E
I
S
V
P
V
M
V
T
G
M
T
G
G
-
R
-
N
E
L
G
R
I
N
K
I
I
A
E
V
A
E
K
F
G
I
P
M
G
V
G
S
Q
R
V
A
I
E
K
A
E
A
R
E
S
F
A
I
V
R
K
V
A
P
T
I
P
I
I
A
N
L
G
M---
P
Q
L
V
----
K
G
Y
G
L
K
EFQD
A
I
Q
M
I
E
A
D
A
I
A
V
H
L
N
P
A
Q
E
V
F
Q
P
E
G
E
P
E
Y
Q
I
Y
A
L
E
K
L
R
D
I
S
K
E
L
--
S
V
P
I
I
V
K
E
S
G
N
G
I
S
M
E
T
A
K
L
L
Y
S
Y
G
I
K
N
F
D
T
S
G
Q
G
G
T
N
W
I
A
I
E
MI
R
D
I
R
R
GNWKA
E
S
A
-
K
N
F
-
L
D
W
G
V
P
T
A
A
S
I
M
E
V
R
Y
-
S
V
P
D
S
F
L
V
G
S
G
G
I
R
S
G
L
D
A
A
K
A
I
A
L
G
A
D
I
A
G
M
A
L
P
V
L
K
S
A
IE
G
K
E
S
L
E
Q
F
F
R
K
I
I
F
---
E
L
K
A
A
M
M
L
T
G
S
K
D
V
D
A
L
K
K
T
S
I
V
I
L
G
K
L
K
E
W
A
E
Y
R
G
I
N
L
-------
24
PsiBlast_CBE
94.13
35%
-82
- C3 -
3VKJ
1
IDI2_SULSH
D:
[7-358]
-----------
R
K
V
E
H
V
E
I
A
A
F
E
N
V
D
G
-
L
S
S
S
TF
L
N
D
V
I
L
V
H
Q
G
F
P
G
I
S
F
S
E
I
N
T
K
T
K
F
F
R
K
E
I
S
V
P
V
M
V
T
G
M
T
G
G
-
R
-
N
E
L
G
R
I
N
K
I
I
A
E
V
A
E
K
F
G
I
P
M
G
V
G
S
Q
R
V
A
I
E
K
A
E
A
R
E
S
F
A
I
V
R
K
V
A
P
T
I
P
I
I
A
N
L
G
M---
P
Q
L
V
----
K
G
Y
G
L
K
EFQD
A
I
Q
M
I
E
A
D
A
I
A
V
H
L
N
P
A
Q
E
V
F
Q
P
E
G
E
P
E
Y
Q
I
Y
A
L
E
K
L
R
D
I
S
K
E
L
--
S
V
P
I
I
V
K
E
S
G
N
G
I
S
M
E
T
A
K
L
L
Y
S
Y
G
I
K
N
F
D
T
S
G
Q
G
G
T
N
W
I
A
I
E
MI
R
D
I
R
R
GNWKA
E
S
A
-
K
N
F
-
L
D
W
G
V
P
T
A
A
S
I
M
E
V
R
Y
-
S
V
P
D
S
F
L
V
G
S
G
G
I
R
S
G
L
D
A
A
K
A
I
A
L
G
A
D
I
A
G
M
A
L
P
V
L
K
S
A
IE
G
K
E
S
L
E
Q
F
F
R
K
I
I
F
---
E
L
K
A
A
M
M
L
T
G
S
K
D
V
D
A
L
K
K
T
S
I
V
I
L
G
K
L
K
E
W
A
E
Y
R
G
I
N
L
-------
51
PsiBlast_CBE
94.00
35%
-81
- C3 -
2ZRV
1
IDI2_SULSH
D:
[7-358]
-----------
R
K
V
E
H
V
E
I
A
A
F
E
N
V
D
G
-
L
S
S
S
TF
L
N
D
V
I
L
V
H
Q
G
F
P
G
I
S
F
S
E
I
N
T
K
T
K
F
F
R
K
E
I
S
V
P
V
M
V
T
G
M
T
G
G
-
R
-
N
E
L
G
R
I
N
K
I
I
A
E
V
A
E
K
F
G
I
P
M
G
V
G
S
Q
R
V
A
I
E
K
A
E
A
R
E
S
F
A
I
V
R
K
V
A
P
T
I
P
I
I
A
N
L
G
M---
P
Q
L
V
----
K
G
Y
G
L
K
EFQD
A
I
Q
M
I
E
A
D
A
I
A
V
H
L
N
P
A
Q
E
V
F
Q
P
E
G
E
P
E
Y
Q
I
Y
A
L
E
K
L
R
D
I
S
K
E
L
--
S
V
P
I
I
V
K
E
S
G
N
G
I
S
M
E
T
A
K
L
L
Y
S
Y
G
I
K
N
F
D
T
S
G
Q
G
G
T
N
W
I
A
I
E
MI
R
D
I
R
R
GNWKA
E
S
A
-
K
N
F
-
L
D
W
G
V
P
T
A
A
S
I
M
E
V
R
Y
-
S
V
P
D
S
F
L
V
G
S
G
G
I
R
S
G
L
D
A
A
K
A
I
A
L
G
A
D
I
A
G
M
A
L
P
V
L
K
S
A
IE
G
K
E
S
L
E
Q
F
F
R
K
I
I
F
---
E
L
K
A
A
M
M
L
T
G
S
K
D
V
D
A
L
K
K
T
S
I
V
I
L
G
K
L
K
E
W
A
E
Y
R
G
I
N
L
-------
114
HHSearch
93.92
41%
-99
- C3 -
1P0K
1
IDI2_BACSU
A:
[21-349]
----------------------------
R
E
T
G
--
L
D
D
I
T
F
V
H
V
S
L
P
D
L
A
L
E
Q
V
D
I
S
T
K
I
G
E
L
S
S
S
S
P
I
F
I
N
A
M
T
G
G
-
G
G
K
L
T
Y
E
I
N
K
S
L
A
R
A
A
S
Q
A
G
I
P
L
A
V
G
S
Q
M
S
A
L
K
D
P
S
E
R
L
S
Y
E
I
V
R
K
E
N
P
N
G
L
I
F
A
N
L
G
----
S
E
A
T
----
A
A
Q
A
K
E
----
A
V
E
M
I
G
A
N
A
L
Q
I
H
L
N
V
I
Q
E
I
--------
F
S
-
G
A
L
K
R
I
E
Q
I
C
S
R
V
--
S
V
P
V
I
V
K
E
V
G
F
G
M
S
K
A
S
A
G
K
L
Y
E
A
G
A
A
A
V
D
I
G
G
----------------------
R
Q
--
I
S
F
F
N
S
W
G
I
S
T
A
A
S
L
A
E
I
R
S
E
F
-
P
A
S
T
M
I
A
S
G
G
L
Q
D
A
L
D
V
A
K
A
I
A
L
G
A
S
C
T
G
M
A
G
H
F
L
K
A
L
--
T
D
S
G
E
E
G
L
L
E
E
I
Q
L
I
L
E
E
L
K
L
I
M
T
V
L
G
A
R
T
I
A
D
L
Q
K
A
P
L
V
I
K
G
E
T
H
H
W
L
T
E
R
G
V
N
T
S
S
Y
S
V
R
-
35
PsiBlast_CBE
93.92
35%
-81
- C3 -
3B04
2
IDI2_SULSH
B:
[7-358]
-----------
R
K
V
E
H
V
E
I
A
A
F
E
N
V
D
G
-
L
S
S
S
TF
L
N
D
V
I
L
V
H
Q
G
F
P
G
I
S
F
S
E
I
N
T
K
T
K
F
F
R
K
E
I
S
V
P
V
M
V
T
G
M
T
G
G
-
R
-
N
E
L
G
R
I
N
K
I
I
A
E
V
A
E
K
F
G
I
P
M
G
V
G
S
Q
R
V
A
I
E
K
A
E
A
R
E
S
F
A
I
V
R
K
V
A
P
T
I
P
I
I
A
N
L
G
M---
P
Q
L
V
----
K
G
Y
G
L
K
EFQD
A
I
Q
M
I
E
A
D
A
I
A
V
H
L
N
P
A
Q
E
V
F
Q
P
E
G
E
P
E
Y
Q
I
Y
A
L
E
K
L
R
D
I
S
K
E
L
--
S
V
P
I
I
V
K
E
S
G
N
G
I
S
M
E
T
A
K
L
L
Y
S
Y
G
I
K
N
F
D
T
S
G
Q
G
G
T
N
W
I
A
I
E
MI
R
D
I
R
R
GNWKA
E
S
A
-
K
N
F
-
L
D
W
G
V
P
T
A
A
S
I
M
E
V
R
Y
-
S
V
P
D
S
F
L
V
G
S
G
G
I
R
S
G
L
D
A
A
K
A
I
A
L
G
A
D
I
A
G
M
A
L
P
V
L
K
S
A
IE
G
K
E
S
L
E
Q
F
F
R
K
I
I
F
---
E
L
K
A
A
M
M
L
T
G
S
K
D
V
D
A
L
K
K
T
S
I
V
I
L
G
K
L
K
E
W
A
E
Y
R
G
I
N
L
-------
55
PsiBlast_CBE
93.78
35%
-87
- C3 -
2ZRU
1
IDI2_SULSH
C:
[9-358]
-------------
V
E
H
V
E
I
A
A
F
E
N
V
D
G
-
L
S
S
S
TF
L
N
D
V
I
L
V
H
Q
G
F
P
G
I
S
F
S
E
I
N
T
K
T
K
F
F
R
K
E
I
S
V
P
V
M
V
T
G
M
T
-----
N
E
L
G
R
I
N
K
I
I
A
E
V
A
E
K
F
G
I
P
M
G
V
G
S
Q
R
V
A
I
E
K
A
E
A
R
E
S
F
A
I
V
R
K
V
A
P
T
I
P
I
I
A
N
L
G
M---
P
Q
L
V
----
K
G
Y
G
L
K
EFQD
A
I
Q
M
I
E
A
D
A
I
A
V
H
L
N
P
A
Q
E
V
F
Q
P
E
G
E
P
E
Y
Q
I
Y
A
L
E
K
L
R
D
I
S
K
E
L
--
S
V
P
I
I
V
K
E
S
G
N
G
I
S
M
E
T
A
K
L
L
Y
S
Y
G
I
K
N
F
D
T
S
G
Q
G
G
T
N
W
I
A
I
E
MI
R
D
I
R
R
GNWKA
E
S
A
-
K
N
F
-
L
D
W
G
V
P
T
A
A
S
I
M
E
V
R
Y
-
S
V
P
D
S
F
L
V
G
S
G
G
I
R
S
G
L
D
A
A
K
A
I
A
L
G
A
D
I
A
G
M
A
L
P
V
L
K
S
A
IE
G
K
E
S
L
E
Q
F
F
R
K
I
I
F
---
E
L
K
A
A
M
M
L
T
G
S
K
D
V
D
A
L
K
K
T
S
I
V
I
L
G
K
L
K
E
W
A
E
Y
R
G
I
N
L
-------
3
PsiBlast_PDB
93.78
41%
-81
- C3 -
4N02
4
IDI2_STRPS
A:
[26-347]
-----------
R
K
D
E
H
I
L
Y
A
L
E
Q
K
S
---
S
Y
N
S
--
F
D
E
V
E
L
I
H
S
S
L
P
L
Y
N
L
D
E
I
D
L
S
T
E
F
A
G
R
K
W
D
F
P
F
Y
I
N
A
M
T
G
G
-
S
-
N
K
G
R
E
I
N
Q
K
L
A
Q
V
A
E
S
C
G
I
L
F
V
T
G
S
Y
S
A
A
L
K
N
P
T
--
D
D
S
F
S
V
K
S
S
H
P
N
L
L
L
G
T
N
I
G
----
L
D
K
P
----
V
E
L
G
L
Q
----
T
V
E
E
M
N
P
V
L
L
Q
V
H
V
N
V
M
Q
E
L
L
M
P
E
G
E
R
K
F
R
-
S
W
Q
S
H
L
A
D
Y
S
K
Q
I
--
P
V
P
I
V
L
K
E
V
G
F
G
M
D
A
K
T
I
E
R
A
Y
E
F
G
V
R
T
V
D
L
S
G
R
G
G
T
S
F
A
Y
I
E
--
N
--
R
R
-----
S
G
Q
-
R
D
Y
L
N
Q
W
G
Q
S
T
M
Q
A
L
L
N
A
Q
E
W
-
K
D
K
V
E
L
L
V
S
G
G
V
R
N
P
L
D
M
I
K
C
L
V
F
G
A
K
A
V
G
L
S
R
T
V
L
E
L
V
--
E
T
Y
T
V
E
E
V
I
G
I
V
Q
G
W
K
A
D
L
R
L
I
M
C
S
L
N
C
A
T
I
A
D
L
Q
K
V
D
Y
L
L
Y
G
K
L
------------------
21
PsiBlast_CBE
93.75
41%
-100
- C3 -
1P0N
2
IDI2_BACSU
B:
[22-349]
-------------------------
E
----
T
G
--
L
D
D
I
T
F
V
H
V
S
L
P
D
L
A
L
E
Q
V
D
I
S
T
K
I
G
E
L
S
S
S
S
P
I
F
I
N
A
M
T
G
G
-
G
G
K
L
T
Y
E
I
N
K
S
L
A
R
A
A
S
Q
A
G
I
P
L
A
V
G
S
Q
M
S
A
L
K
D
P
S
E
R
L
S
Y
E
I
V
R
K
E
N
P
N
G
L
I
F
A
N
L
G
----
S
E
A
T
----
A
A
Q
A
K
E
----
A
V
E
M
I
G
A
N
A
L
Q
I
H
L
N
V
I
Q
E
I
V
M
------
F
S
-
G
A
L
K
R
I
E
Q
I
C
S
R
V
--
S
V
P
V
I
V
K
E
V
G
F
G
M
S
K
A
S
A
G
K
L
Y
E
A
G
A
A
A
V
D
I
G
G
----------------------
R
Q
--
I
S
F
F
N
S
W
G
I
S
T
A
A
S
L
A
E
I
R
-
S
E
F
P
A
S
T
M
I
A
S
G
G
L
Q
D
A
L
D
V
A
K
A
I
A
L
G
A
S
C
T
G
M
A
G
H
F
L
K
A
L
--
T
D
S
G
E
E
G
L
L
E
E
I
Q
L
I
L
E
E
L
K
L
I
M
T
V
L
G
A
R
T
I
A
D
L
Q
K
A
P
L
V
I
K
G
E
T
H
H
W
L
T
E
R
G
V
N
T
S
S
Y
S
V
R
-
14
PsiBlast_PDB
93.75
35%
-81
- C3 -
3VKJ
1
IDI2_SULSH
A:
[7-358]
-----------
R
K
V
E
H
V
E
I
A
A
F
E
N
V
D
G
-
L
S
S
S
TF
L
N
D
V
I
L
V
H
Q
G
F
P
G
I
S
F
S
E
I
N
T
K
T
K
F
F
R
K
E
I
S
V
P
V
M
V
T
G
M
T
G
G
-
R
-
N
E
L
G
R
I
N
K
I
I
A
E
V
A
E
K
F
G
I
P
M
G
V
G
S
Q
R
V
A
I
E
K
A
E
A
R
E
S
F
A
I
V
R
K
V
A
P
T
I
P
I
I
A
N
L
G
M
---
P
Q
L
V
----
K
G
Y
G
L
K
E
F
Q
D
A
I
Q
M
I
E
A
D
A
I
A
V
H
L
N
P
A
Q
E
V
F
Q
P
E
G
E
P
E
Y
Q
I
Y
A
L
E
K
L
R
D
I
S
K
E
L
--
S
V
P
I
I
V
K
E
S
G
N
G
I
S
M
E
T
A
K
L
L
Y
S
Y
G
I
K
N
F
D
T
S
G
Q
G
G
T
N
W
I
A
I
E
M
I
R
D
I
R
R
GNWK
A
E
S
A
-
K
N
F
-
L
D
W
G
V
P
T
A
A
S
I
M
E
V
R
Y
-
S
V
P
D
S
F
L
V
G
S
G
G
I
R
S
G
L
D
A
A
K
A
I
A
L
G
A
D
I
A
G
M
A
L
P
V
L
K
S
A
I
E
G
K
E
S
L
E
Q
F
F
R
K
I
I
F
---
E
L
K
A
A
M
M
L
T
G
S
K
D
V
D
A
L
K
K
T
S
I
V
I
L
G
K
L
K
E
W
A
E
Y
R
G
I
N
L
-------
5
PsiBlast_PDB
93.72
35%
-81
- C3 -
2ZRV
1
IDI2_SULSH
A:
[7-358]
-----------
R
K
V
E
H
V
E
I
A
A
F
E
N
V
D
G
-
L
S
S
S
TF
L
N
D
V
I
L
V
H
Q
G
F
P
G
I
S
F
S
E
I
N
T
K
T
K
F
F
R
K
E
I
S
V
P
V
M
V
T
G
M
T
G
G
-
R
-
N
E
L
G
R
I
N
K
I
I
A
E
V
A
E
K
F
G
I
P
M
G
V
G
S
Q
R
V
A
I
E
K
A
E
A
R
E
S
F
A
I
V
R
K
V
A
P
T
I
P
I
I
A
N
L
G
M
---
P
Q
L
V
----
K
G
Y
G
L
K
E
F
Q
D
A
I
Q
M
I
E
A
D
A
I
A
V
H
L
N
P
A
Q
E
V
F
Q
P
E
G
E
P
E
Y
Q
I
Y
A
L
E
K
L
R
D
I
S
K
E
L
--
S
V
P
I
I
V
K
E
S
G
N
G
I
S
M
E
T
A
K
L
L
Y
S
Y
G
I
K
N
F
D
T
S
G
Q
G
G
T
N
W
I
A
I
E
M
I
R
D
I
R
R
GNWK
A
E
S
A
-
K
N
F
-
L
D
W
G
V
P
T
A
A
S
I
M
E
V
R
Y
-
S
V
P
D
S
F
L
V
G
S
G
G
I
R
S
G
L
D
A
A
K
A
I
A
L
G
A
D
I
A
G
M
A
L
P
V
L
K
S
A
I
E
G
K
E
S
L
E
Q
F
F
R
K
I
I
F
---
E
L
K
A
A
M
M
L
T
G
S
K
D
V
D
A
L
K
K
T
S
I
V
I
L
G
K
L
K
E
W
A
E
Y
R
G
I
N
L
-------
45
PsiBlast_CBE
93.62
35%
-81
- C3 -
2ZRX
3
IDI2_SULSH
D:
[7-358]
-----------
R
K
V
E
H
V
E
I
A
A
F
E
N
V
D
G
-
L
S
S
S
TF
L
N
D
V
I
L
V
H
Q
G
F
P
G
I
S
F
S
E
I
N
T
K
T
K
F
F
R
K
E
I
S
V
P
V
M
V
T
G
M
T
G
G
-
R
-
N
E
L
G
R
I
N
K
I
I
A
E
V
A
E
K
F
G
I
P
M
G
V
G
S
Q
R
V
A
I
E
K
A
E
A
R
E
S
F
A
I
V
R
K
V
A
P
T
I
P
I
I
A
N
L
G
M---
P
Q
L
V
----
K
G
Y
G
L
K
EFQD
A
I
Q
M
I
E
A
D
A
I
A
V
H
L
N
P
A
Q
E
V
F
Q
P
E
G
E
P
E
Y
Q
I
Y
A
L
E
K
L
R
D
I
S
K
E
L
--
S
V
P
I
I
V
K
E
S
G
N
G
I
S
M
E
T
A
K
L
L
Y
S
Y
G
I
K
N
F
D
T
S
G
Q
G
G
T
N
W
I
A
I
E
MI
R
D
I
R
R
GNWKA
E
S
A
-
K
N
F
-
L
D
W
G
V
P
T
A
A
S
I
M
E
V
R
Y
-
S
V
P
D
S
F
L
V
G
S
G
G
I
R
S
G
L
D
A
A
K
A
I
A
L
G
A
D
I
A
G
M
A
L
P
V
L
K
S
A
IE
G
K
E
S
L
E
Q
F
F
R
K
I
I
F
---
E
L
K
A
A
M
M
L
T
G
S
K
D
V
D
A
L
K
K
T
S
I
V
I
L
G
K
L
K
E
W
A
E
Y
R
G
I
N
L
-------
36
PsiBlast_CBE
93.59
35%
-80
- C3 -
3B03
2
IDI2_SULSH
D:
[7-358]
-----------
R
K
V
E
H
V
E
I
A
A
F
E
N
V
D
G
-
L
S
S
S
TF
L
N
D
V
I
L
V
H
Q
G
F
P
G
I
S
F
S
E
I
N
T
K
T
K
F
F
R
K
E
I
S
V
P
V
M
V
T
G
M
T
G
G
-
R
-
N
E
L
G
R
I
N
K
I
I
A
E
V
A
E
K
F
G
I
P
M
G
V
G
S
Q
R
V
A
I
E
K
A
E
A
R
E
S
F
A
I
V
R
K
V
A
P
T
I
P
I
I
A
N
L
G
M---
P
Q
L
V
----
K
G
Y
G
L
K
EFQD
A
I
Q
M
I
E
A
D
A
I
A
V
H
L
N
P
A
Q
E
V
F
Q
P
E
G
E
P
E
Y
Q
I
Y
A
L
E
K
L
R
D
I
S
K
E
L
--
S
V
P
I
I
V
K
E
S
G
N
G
I
S
M
E
T
A
K
L
L
Y
S
Y
G
I
K
N
F
D
T
S
G
Q
G
G
T
N
W
I
A
I
E
MI
R
D
I
R
R
GNWKA
E
S
A
-
K
N
F
-
L
D
W
G
V
P
T
A
A
S
I
M
E
V
R
Y
-
S
V
P
D
S
F
L
V
G
S
G
G
I
R
S
G
L
D
A
A
K
A
I
A
L
G
A
D
I
A
G
M
A
L
P
V
L
K
S
A
IE
G
K
E
S
L
E
Q
F
F
R
K
I
I
F
---
E
L
K
A
A
M
M
L
T
G
S
K
D
V
D
A
L
K
K
T
S
I
V
I
L
G
K
L
K
E
W
A
E
Y
R
G
I
N
L
-------
102
Fugue
93.55
40%
-96
- C3 -
1P0K
1
IDI2_BACSU
B:
[22-349]
-----------------------------
E
T
G
--
L
D
D
I
T
F
V
H
V
S
L
P
D
L
A
L
E
Q
V
D
I
S
T
K
I
G
E
L
S
S
S
S
P
I
F
I
N
A
M
T
G
G
G
G
-
K
L
T
Y
E
I
N
K
S
L
A
R
A
A
S
Q
A
G
I
P
L
A
V
G
S
Q
M
S
A
L
K
D
P
S
E
R
L
S
Y
E
I
V
R
K
E
N
P
N
G
L
I
F
A
N
L
G
----
S
E
A
T
----
A
A
Q
A
K
E
----
A
V
E
M
I
G
A
N
A
L
Q
I
H
L
N
V
I
Q
E
I
V
M
R
S
----
F
S
-
G
A
L
K
R
I
E
Q
I
C
S
R
V
--
S
V
P
V
I
V
K
E
V
G
F
G
M
S
K
A
S
A
G
K
L
Y
E
A
G
A
A
A
V
D
I
G
G
R
Q
I
S
F
F
N
------------------------
S
W
G
I
S
T
A
A
S
L
A
E
I
R
S
E
F
-
P
A
S
T
M
I
A
S
G
G
L
Q
D
A
L
D
V
A
K
A
I
A
L
G
A
S
C
T
G
M
A
G
H
F
L
K
A
L
--
T
D
S
G
E
E
G
L
L
E
E
I
Q
L
I
L
E
E
L
K
L
I
M
T
V
L
G
A
R
T
I
A
D
L
Q
K
A
P
L
V
I
K
G
E
T
H
H
W
L
T
E
R
G
V
N
T
S
S
Y
S
V
R
-
38
PsiBlast_CBE
93.54
35%
-81
- C3 -
3B03
1
IDI2_SULSH
B:
[7-358]
-----------
R
K
V
E
H
V
E
I
A
A
F
E
N
V
D
G
-
L
S
S
S
TF
L
N
D
V
I
L
V
H
Q
G
F
P
G
I
S
F
S
E
I
N
T
K
T
K
F
F
R
K
E
I
S
V
P
V
M
V
T
G
M
T
G
G
-
R
-
N
E
L
G
R
I
N
K
I
I
A
E
V
A
E
K
F
G
I
P
M
G
V
G
S
Q
R
V
A
I
E
K
A
E
A
R
E
S
F
A
I
V
R
K
V
A
P
T
I
P
I
I
A
N
L
G
M
---
P
Q
L
V
----
K
G
Y
G
L
K
E
F
Q
D
A
I
Q
M
I
E
A
D
A
I
A
V
H
L
N
P
A
Q
E
V
F
Q
P
E
G
E
P
E
Y
Q
I
Y
A
L
E
K
L
R
D
I
S
K
E
L
--
S
V
P
I
I
V
K
E
S
G
N
G
I
S
M
E
T
A
K
L
L
Y
S
Y
G
I
K
N
F
D
T
S
G
Q
G
G
T
N
W
I
A
I
E
M
I
R
D
I
R
R
GNWK
A
E
S
A
-
K
N
F
-
L
D
W
G
V
P
T
A
A
S
I
M
E
V
R
Y
-
S
V
P
D
S
F
L
V
G
S
G
G
I
R
S
G
L
D
A
A
K
A
I
A
L
G
A
D
I
A
G
M
A
L
P
V
L
K
S
A
I
E
G
K
E
S
L
E
Q
F
F
R
K
I
I
F
---
E
L
K
A
A
M
M
L
T
G
S
K
D
V
D
A
L
K
K
T
S
I
V
I
L
G
K
L
K
E
W
A
E
Y
R
G
I
N
L
-------
8
PsiBlast_PDB
93.48
35%
-80
- C3 -
2ZRY
3
IDI2_SULSH
A:
[7-358]
-----------
R
K
V
E
H
V
E
I
A
A
F
E
N
V
D
G
-
L
S
S
S
TF
L
N
D
V
I
L
V
H
Q
G
F
P
G
I
S
F
S
E
I
N
T
K
T
K
F
F
R
K
E
I
S
V
P
V
M
V
T
G
M
T
G
G
-
R
-
N
E
L
G
R
I
N
K
I
I
A
E
V
A
E
K
F
G
I
P
M
G
V
G
S
Q
R
V
A
I
E
K
A
E
A
R
E
S
F
A
I
V
R
K
V
A
P
T
I
P
I
I
A
N
L
G
M
---
P
Q
L
V
----
K
G
Y
G
L
K
E
F
Q
D
A
I
Q
M
I
E
A
D
A
I
A
V
H
L
N
P
A
Q
E
V
F
Q
P
E
G
E
P
E
Y
Q
I
Y
A
L
E
K
L
R
D
I
S
K
E
L
--
S
V
P
I
I
V
K
E
S
G
N
G
I
S
M
E
T
A
K
L
L
Y
S
Y
G
I
K
N
F
D
T
S
G
Q
G
G
T
N
W
I
A
I
E
M
I
R
D
I
R
R
GNWK
A
E
S
A
-
K
N
F
-
L
D
W
G
V
P
T
A
A
S
I
M
E
V
R
Y
-
S
V
P
D
S
F
L
V
G
S
G
G
I
R
S
G
L
D
A
A
K
A
I
A
L
G
A
D
I
A
G
M
A
L
P
V
L
K
S
A
I
E
G
K
E
S
L
E
Q
F
F
R
K
I
I
F
---
E
L
K
A
A
M
M
L
T
G
S
K
D
V
D
A
L
K
K
T
S
I
V
I
L
G
K
L
K
E
W
A
E
Y
R
G
I
N
L
-------
120
HHSearch
82.31
32%
-87
- C3 -
1VCF
2
IDI2_THET2
A:
[23-329]
---------------------------K
T
T
T
G
--
L
E
G
F
R
L
R
Y
Q
A
L
A
G
L
A
L
S
E
V
D
L
T
T
P
F
L
G
K
T
L
K
A
P
F
L
I
G
A
M
T
-----
E
N
G
E
R
I
N
L
A
L
A
E
A
A
E
A
L
G
V
G
M
M
L
G
S
G
R
I
L
L
E
R
P
E
A
L
R
S
F
-
R
V
R
K
V
A
P
K
A
L
L
I
A
N
L
G
----
L
A
Q
L
RRYG
R
D
D
L
L
R
----
L
V
E
M
L
E
A
D
A
L
A
F
H
V
N
P
L
Q
E
A
V
Q
R
-
G
D
T
----
D
F
R
G
L
V
E
R
L
A
E
L
L
PL
P
F
P
V
M
V
K
E
V
G
H
G
L
S
R
E
A
A
L
A
L
R
D
L
P
L
A
A
V
D
V
A
G
A
G
G
T
S
W
A
R
V
E
--
E
W
V
-------------
E
L
C
E
I
G
I
P
T
A
R
A
I
L
E
V
R
E
V
L
P
-
H
L
P
L
V
A
S
G
G
V
Y
T
G
T
D
G
A
K
A
L
A
L
G
A
D
L
L
A
V
A
R
P
L
L
R
P
A
--
L
-
E
G
A
E
R
V
A
A
W
I
G
D
Y
L
E
E
L
R
T
A
L
F
A
I
G
A
R
N
P
K
E
A
R
G
R
V
-------------------------
58
PsiBlast_CBE
71.03
34%
-65
- C3 -
3DH7
2
?
B:
[9-270]
------------
K
H
L
E
A
C
L
E
G
E
V
A
Y
Q
K
-
T
T
T
G
--
L
E
G
F
R
L
R
Y
Q
A
L
A
G
L
A
L
S
E
V
D
L
T
T
P
F
L
G
K
T
L
K
A
P
F
L
I
G
A
M
T
--------
E
R
I
N
L
A
L
A
E
A
A
E
A
L
G
V
G
M
M
L
G
S
G
R
I
L
L
E
R
P
E
A
L
R
S
F
R
-
V
R
K
V
A
P
K
A
L
L
I
A
N
L
G
LAQL
R
R
Y
G
----
R
D
D
L
L
R
----
L
V
E
M
L
E
A
D
A
L
A
F
H
V
N
P
L
Q
E
A
V
-
Q
R
G
D
T
D
F
R
-
G
L
V
E
R
L
A
E
L
L
P
L
---
P
F
P
V
M
V
K
E
V
G
H
G
L
S
R
E
A
A
L
A
L
R
D
L
P
L
A
A
V
D
V
A
G
A
G
G
T
S
W
A
R
V
E
--
E
W
V
R
F
-----
G
E
V
R
H
P
E
L
C
E
I
G
I
P
T
A
R
A
I
L
E
V
R
-
E
V
L
P
H
L
P
L
V
A
S
G
G
V
Y
T
G
T
D
---------------------------------------------------------------------------------------
15
PsiBlast_PDB
70.72
34%
-65
- C3 -
3DH7
1
?
A:
[9-270]
------------
K
H
L
E
A
C
L
E
G
E
V
A
Y
Q
K
-
T
T
T
G
--
L
E
G
F
R
L
R
Y
Q
A
L
A
G
L
A
L
S
E
V
D
L
T
T
P
F
L
G
K
T
L
K
A
P
F
L
I
G
A
M
T
--------
E
R
I
N
L
A
L
A
E
A
A
E
A
L
G
V
G
M
M
L
G
S
G
R
I
L
L
E
R
P
E
A
L
R
S
F
R
-
V
R
K
V
A
P
K
A
L
L
I
A
N
L
G
LAQL
R
R
Y
G
----
R
D
D
L
L
R
----
L
V
E
M
L
E
A
D
A
L
A
F
H
V
N
P
L
Q
E
A
V
-
Q
R
G
D
T
D
F
R
-
G
L
V
E
R
L
A
E
L
L
P
L
---
P
F
P
V
M
V
K
E
V
G
H
G
L
S
R
E
A
A
L
A
L
R
D
L
P
L
A
A
V
D
V
A
G
A
G
G
T
S
W
A
R
V
E
--
E
W
V
R
F
-----
G
E
V
R
H
P
E
L
C
E
I
G
I
P
T
A
R
A
I
L
E
V
R
-
E
V
L
P
H
L
P
L
V
A
S
G
G
V
Y
T
G
T
D
---------------------------------------------------------------------------------------
57
PsiBlast_CBE
70.18
34%
-71
- C3 -
3DH7
1
?
C:
[9-270]
------------
K
H
L
E
A
C
L
E
G
E
V
A
Y
Q
K
-
T
T
T
G
--
L
E
G
F
R
L
R
Y
Q
A
L
A
G
L
A
L
S
E
V
D
L
T
T
P
F
L
G
K
T
L
K
A
P
F
L
I
G
A
M
T
--------
E
R
I
N
L
A
L
A
E
A
A
E
A
L
G
V
G
M
M
L
G
S
G
R
I
L
L
E
R
P
E
A
L
R
--
R
-
V
R
K
V
A
P
K
A
L
L
I
A
N
L
G
LAQL
R
R
Y
G
----
R
D
D
L
L
R
----
L
V
E
M
L
E
A
D
A
L
A
F
H
V
N
P
L
Q
E
A
V
-
Q
R
G
D
T
D
F
R
-
G
L
V
E
R
L
A
E
L
L
P
L
---
P
F
P
V
M
V
K
E
V
G
H
G
L
S
R
E
A
A
L
A
L
R
D
L
P
L
A
A
V
D
V
A
G
A
G
G
T
S
W
A
R
V
E
--
E
W
V
R
F
-----
G
E
V
R
H
P
E
L
C
E
I
G
I
P
T
A
R
A
I
L
E
V
R
-
E
V
L
P
H
L
P
L
V
A
S
G
G
V
Y
T
G
T
D
---------------------------------------------------------------------------------------
16
PsiBlast_PDB
70.02
33%
-85
- C3 -
1VCF
2
IDI2_THET2
A:
[23-270]
--------------------------
K
-
T
T
T
G
--
L
E
G
F
R
L
R
Y
Q
A
L
A
G
L
A
L
S
E
V
D
L
T
T
P
F
L
G
K
T
L
K
A
P
F
L
I
G
A
M
T
-----
E
N
G
E
R
I
N
L
A
L
A
E
A
A
E
A
L
G
V
G
M
M
L
G
S
G
R
I
L
L
E
R
P
E
A
L
R
S
F
R
-
V
R
K
V
A
P
K
A
L
L
I
A
N
L
G
LAQL
R
R
Y
G
----
R
D
D
L
L
R
----
L
V
E
M
L
E
A
D
A
L
A
F
H
V
N
P
L
Q
E
A
V
-
Q
R
G
D
T
D
F
R
-
G
L
V
E
R
L
A
E
L
L
P
L
---
P
F
P
V
M
V
K
E
V
G
H
G
L
S
R
E
A
A
L
A
L
R
D
L
P
L
A
A
V
D
V
A
G
A
G
G
T
S
W
A
R
V
E
--
E
W
V
-------------
E
L
C
E
I
G
I
P
T
A
R
A
I
L
E
V
R
-
E
V
L
P
H
L
P
L
V
A
S
G
G
V
Y
T
G
T
D
---------------------------------------------------------------------------------------
17
PsiBlast_PDB
68.47
33%
-67
- C3 -
1VCG
1
IDI2_THET2
A:
[9-270]
------------
K
H
L
E
A
C
L
E
G
E
V
A
Y
Q
K
-
T
T
T
G
--
L
E
G
F
R
L
R
Y
Q
A
L
A
G
L
A
L
S
E
V
D
L
T
T
P
F
L
G
K
T
L
K
A
P
F
L
I
G
A
M
T
--------
E
R
I
N
L
A
L
A
E
A
A
E
A
L
G
V
G
M
M
L
G
S
G
R
I
L
L
E
R
P
--------
V
R
K
V
A
P
K
A
L
L
I
A
N
L
G
LAQL
R
R
Y
G
----
R
D
D
L
L
R
----
L
V
E
M
L
E
A
D
A
L
A
F
H
V
N
P
L
Q
E
A
V
-
Q
R
G
D
T
D
F
R
-
G
L
V
E
R
L
A
E
L
L
P
L
---
P
F
P
V
M
V
K
E
V
G
H
G
L
S
R
E
A
A
L
A
L
R
D
L
P
L
A
A
V
D
V
A
G
A
G
G
T
S
W
A
R
V
E
--
E
W
V
R
F
-----
G
E
V
R
H
P
E
L
C
E
I
G
I
P
T
A
R
A
I
L
E
V
R
-
E
V
L
P
H
L
P
L
V
A
S
G
G
V
Y
T
G
T
D
---------------------------------------------------------------------------------------