@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1429: (2016-03-24 )
MQNKRLIILLECAIFAAVAMVLSFIPLDIGSSFSISLGMIPMYVIAIRRGFWAAGFAGLLWGLLHFLTGKAYILMPSQAIIEYILAFSFIAFSGVFSKQVRSNLAANQLKKAIEWAWGTMIIGGLARYFWHYVAGVLFWGAYAFQGWGAQLFSIVMNGASCLGTVLVSGIIISILLKTSPKLFLPK
Atome Classification :
(20 SA)
....-.....10----.........20........30........40........50........60........70........80........90........100.......110.......120.......130...----....140.......150.......160.......170.......180....--
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MQNK-
R
L
I
I
L
L
-----
E
C
A
I
F
A
A
V
A
M
V
L
S
F
IPLDIGSS
F
S
I
SL
G
M
I
P
M
Y
V
I
A
I
RRG
F
W
A
A
G
F
A
G
L
L
W
G
L
L
H
F
LTG
K
A
Y
I
L
M
P
S
Q
A
I
I
E
Y
I
L
A
F
S
F
I
A
F
S
G
V
F
S
K
Q
V
R
S
N
L
A
A
N
Q
L
K
K
A
I
E
W
A
W
G
T
M
I
I
G
G
L
A
R
Y
F
W
H
Y
V
A
G
----
V
L
F
W
G
A
Y
A
F
Q
G
W
G
A
Q
L
F
S
I
V
M
N
G
A
S
C
L
G
T
V
L
V
S
G
I
I
I
S
I
L
LKTSPKLFLPK--
9
PsiBlast_CBE
97.86
99%
-176
- C1 -
4TKR
11
?
B:
[29-213]
M
Q
N
K
-
R
L
I
I
L
L
-----
E
C
A
I
F
A
A
V
A
M
V
L
S
F
I
P
L
D
I
G
S
S
F
S
I
S
L
G
M
I
P
M
Y
V
I
A
I
R
R
G
F
W
A
A
G
F
A
G
L
L
W
G
L
L
H
F
L
T
G
K
A
Y
I
L
M
P
S
Q
A
I
I
E
Y
I
L
A
F
S
F
I
A
F
S
G
V
F
S
K
Q
V
R
S
N
L
A
A
N
Q
L
K
K
A
I
E
W
A
W
G
T
M
I
I
G
G
V
A
R
Y
F
W
H
Y
V
A
G
----
V
L
F
W
G
A
Y
A
F
Q
G
W
G
A
Q
L
F
S
I
V
M
N
G
A
S
C
L
G
T
V
L
V
S
G
I
I
I
S
I
L
L
K
T
S
P
K
L
F
L
P
---
1
PsiBlast_PDB
96.75
99%
-175
- C1 -
4TKR
7
?
A:
[31-213]
--
N
K
-
R
L
I
I
L
L
-----
E
C
A
I
F
A
A
V
A
M
V
L
S
F
I
P
L
D
I
G
S
S
F
S
I
S
L
G
M
I
P
M
Y
V
I
A
I
R
R
G
F
W
A
A
G
F
A
G
L
L
W
G
L
L
H
F
L
T
G
K
A
Y
I
L
M
P
S
Q
A
I
I
E
Y
I
L
A
F
S
F
I
A
F
S
G
V
F
S
K
Q
V
R
S
N
L
A
A
N
Q
L
K
K
A
I
E
W
A
W
G
T
M
I
I
G
G
V
A
R
Y
F
W
H
Y
V
A
G
----
V
L
F
W
G
A
Y
A
F
Q
G
W
G
A
Q
L
F
S
I
V
M
N
G
A
S
C
L
G
T
V
L
V
S
G
I
I
I
S
I
L
L
K
T
S
P
K
L
F
L
P
---
11
PsiBlast_CBE
74.42
37%
-167
- C1 -
4MES
16
?
B:
[7-178]
--
N
V
-
R
L
--
L
T
-----
E
I
A
F
M
A
A
L
A
F
I
I
S
L
I
P
N
T
V
Y
G
W
I
I
V
E
I
A
C
I
P
I
L
L
L
S
L
R
R
G
L
T
A
G
L
V
G
G
L
I
W
G
I
L
S
M
I
T
G
H
A
Y
I
L
S
L
S
Q
A
F
L
E
Y
L
V
A
P
V
S
L
G
I
A
G
L
F
----
R
Q
K
T
A
P
L
K
L
A
P
V
L
---
L
G
T
F
-
V
A
V
L
L
K
Y
F
F
H
F
I
A
G
----
I
I
F
W
S
Q
Y
A
W
K
G
W
G
A
V
A
Y
S
L
A
V
N
G
I
S
G
I
L
T
A
I
A
A
F
V
I
L
I
I
F
V
K
K
F
P
K
L
F
I
----
16
PsiBlast_CBE
74.34
37%
-165
- C1 -
3RLB
8
?
B:
[17-188]
--
N
V
-
R
L
--
L
T
-----
E
I
A
F
M
A
A
L
A
F
I
I
S
L
I
P
N
T
V
Y
G
W
I
I
V
E
I
A
C
I
P
I
L
L
L
S
L
R
R
G
L
T
A
G
L
V
G
G
L
I
W
G
I
L
S
M
I
T
G
H
A
Y
I
L
S
L
S
Q
A
F
L
E
Y
L
V
A
P
V
S
L
G
I
A
G
L
F
----
R
Q
K
T
A
P
L
K
L
A
P
V
L
---
L
G
T
F
-
V
A
V
L
L
K
Y
F
F
H
F
I
A
G
----
I
I
F
W
S
Q
Y
A
W
K
G
W
G
A
V
A
Y
S
L
A
V
N
G
I
S
G
I
L
T
A
I
A
A
F
V
I
L
I
I
F
V
K
K
F
P
K
L
F
I
----
4
PsiBlast_PDB
74.06
37%
-163
- C1 -
3RLB
8
?
A:
[17-188]
--
N
V
-
R
L
--
L
T
-----
E
I
A
F
M
A
A
L
A
F
I
I
S
L
I
P
N
T
V
Y
G
W
I
I
V
E
I
A
C
I
P
I
L
L
L
S
L
R
R
G
L
T
A
G
L
V
G
G
L
I
W
G
I
L
S
M
I
T
G
H
A
Y
I
L
S
L
S
Q
A
F
L
E
Y
L
V
A
P
V
S
L
G
I
A
G
L
F
----
R
Q
K
T
A
P
L
K
L
A
P
V
L
---
L
G
T
F
-
V
A
V
L
L
K
Y
F
F
H
F
I
A
G
----
I
I
F
W
S
Q
Y
A
W
K
G
W
G
A
V
A
Y
S
L
A
V
N
G
I
S
G
I
L
T
A
I
A
A
F
V
I
L
I
I
F
V
K
K
F
P
K
L
F
I
----
7
PsiBlast_PDB
73.69
37%
-161
- C1 -
4POP
29
THIT_LACLM
A:
[17-188]
--
N
V
-
R
L
--
L
T
-----
E
I
A
F
M
A
A
L
A
F
I
I
S
L
I
P
N
T
V
Y
G
W
I
I
V
E
I
A
C
I
P
I
L
L
L
S
L
R
R
G
L
T
A
G
L
V
G
G
L
I
W
G
I
L
S
M
I
T
G
H
A
Y
I
L
S
L
S
Q
A
F
L
E
Y
L
V
A
P
V
S
L
G
I
A
G
L
F
----
R
Q
K
T
A
P
L
K
L
A
P
V
L
---
L
G
T
F
-
V
A
V
L
L
K
Y
F
F
H
F
I
A
G
----
I
I
F
W
S
Q
Y
A
W
K
G
W
G
A
V
A
Y
S
L
A
V
N
G
I
S
G
I
L
T
A
I
A
A
F
V
I
L
I
I
F
V
K
K
F
P
K
L
F
I
----
2
PsiBlast_PDB
73.52
37%
-161
- C1 -
4MES
29
?
A:
[7-178]
--
N
V
-
R
L
--
L
T
-----
E
I
A
F
M
A
A
L
A
F
I
I
S
L
I
P
N
T
V
Y
G
W
I
I
V
E
I
A
C
I
P
I
L
L
L
S
L
R
R
G
L
T
A
G
L
V
G
G
L
I
W
G
I
L
S
M
I
T
G
H
A
Y
I
L
S
L
S
Q
A
F
L
E
Y
L
V
A
P
V
S
L
G
I
A
G
L
F
----
R
Q
K
T
A
P
L
K
L
A
P
V
L
---
L
G
T
F
-
V
A
V
L
L
K
Y
F
F
H
F
I
A
G
----
I
I
F
W
S
Q
Y
A
W
K
G
W
G
A
V
A
Y
S
L
A
V
N
G
I
S
G
I
L
T
A
I
A
A
F
V
I
L
I
I
F
V
K
K
F
P
K
L
F
I
----
6
PsiBlast_PDB
73.39
37%
-167
- C1 -
4MUU
22
?
A:
[17-188]
--
N
V
-
R
L
--
L
T
-----
E
I
A
F
M
A
A
L
A
F
I
I
S
L
I
P
N
T
V
Y
G
W
I
I
V
E
I
A
C
I
P
I
L
L
L
S
L
R
R
G
L
T
A
G
L
V
G
G
L
I
W
G
I
L
S
M
I
T
G
H
A
Y
I
L
S
L
S
Q
A
F
L
E
Y
L
V
A
P
V
S
L
G
I
A
G
L
F
----
R
Q
K
T
A
P
L
K
L
A
P
V
L
---
L
G
T
F
-
V
A
V
L
L
K
Y
F
F
H
F
I
A
G
----
I
I
F
W
S
Q
Y
A
W
K
G
W
G
A
V
A
Y
S
L
A
V
N
G
I
S
G
I
L
T
A
I
A
A
F
V
I
L
I
I
F
V
K
K
F
P
K
L
F
I
----
8
PsiBlast_PDB
73.18
37%
-166
- C1 -
4POV
25
THIT_LACLM
A:
[17-188]
--
N
V
-
R
L
--
L
T
-----
E
I
A
F
M
A
A
L
A
F
I
I
S
L
I
P
N
T
V
Y
G
W
I
I
V
E
I
A
C
I
P
I
L
L
L
S
L
R
R
G
L
T
A
G
L
V
G
G
L
I
W
G
I
L
S
M
I
T
G
H
A
Y
I
L
S
L
S
Q
A
F
L
E
Y
L
V
A
P
V
S
L
G
I
A
G
L
F
----
R
Q
K
T
A
P
L
K
L
A
P
V
L
---
L
G
T
F
-
V
A
V
L
L
K
Y
F
F
H
F
I
A
G
----
I
I
F
W
S
Q
Y
A
W
K
G
W
G
A
V
A
Y
S
L
A
V
N
G
I
S
G
I
L
T
A
I
A
A
F
V
I
L
I
I
F
V
K
K
F
P
K
L
F
I
----
15
PsiBlast_CBE
72.97
37%
-163
- C1 -
4MHW
13
?
B:
[17-188]
--
N
V
-
R
L
--
L
T
-----
E
I
A
F
M
A
A
L
A
F
I
I
S
L
I
P
N
T
V
Y
G
W
I
I
V
E
I
A
C
I
P
I
L
L
L
S
L
R
R
G
L
T
A
G
L
V
G
G
L
I
W
G
I
L
S
M
I
T
G
H
A
Y
I
L
S
L
S
Q
A
F
L
E
Y
L
V
A
P
V
S
L
G
I
A
G
L
F
----
R
Q
K
T
A
P
L
K
L
A
P
V
L
---
L
G
T
F
-
V
A
V
L
L
K
Y
F
F
H
F
I
A
G
----
I
I
F
W
S
Q
Y
A
W
K
G
W
G
A
V
A
Y
S
L
A
V
N
G
I
S
G
I
L
T
A
I
A
A
F
V
I
L
I
I
F
V
K
K
F
P
K
L
F
I
----
10
PsiBlast_CBE
72.85
37%
-164
- C1 -
4N4D
14
?
B:
[7-178]
--
N
V
-
R
L
--
L
T
-----
E
I
A
F
M
A
A
L
A
F
I
I
S
L
I
P
N
T
V
Y
G
W
I
I
V
E
I
A
C
I
P
I
L
L
L
S
L
R
R
G
L
T
A
G
L
V
G
G
L
I
W
G
I
L
S
M
I
T
G
H
A
Y
I
L
S
L
S
Q
A
F
L
E
Y
L
V
A
P
V
S
L
G
I
A
G
L
F
----
R
Q
K
T
A
P
L
K
L
A
P
V
L
---
L
G
T
F
-
V
A
V
L
L
K
Y
F
F
H
F
I
A
G
----
I
I
F
W
S
Q
Y
A
W
K
G
W
G
A
V
A
Y
S
L
A
V
N
G
I
S
G
I
L
T
A
I
A
A
F
V
I
L
I
I
F
V
K
K
F
P
K
L
F
I
----
5
PsiBlast_PDB
72.77
37%
-161
- C1 -
4MHW
22
?
A:
[17-188]
--
N
V
-
R
L
--
L
T
-----
E
I
A
F
M
A
A
L
A
F
I
I
S
L
I
P
N
T
V
Y
G
W
I
I
V
E
I
A
C
I
P
I
L
L
L
S
L
R
R
G
L
T
A
G
L
V
G
G
L
I
W
G
I
L
S
M
I
T
G
H
A
Y
I
L
S
L
S
Q
A
F
L
E
Y
L
V
A
P
V
S
L
G
I
A
G
L
F
----
R
Q
K
T
A
P
L
K
L
A
P
V
L
---
L
G
T
F
-
V
A
V
L
L
K
Y
F
F
H
F
I
A
G
----
I
I
F
W
S
Q
Y
A
W
K
G
W
G
A
V
A
Y
S
L
A
V
N
G
I
S
G
I
L
T
A
I
A
A
F
V
I
L
I
I
F
V
K
K
F
P
K
L
F
I
----
13
PsiBlast_CBE
72.76
37%
-161
- C1 -
4POP
8
THIT_LACLM
B:
[17-188]
--
N
V
-
R
L
--
L
T
-----
E
I
A
F
M
A
A
L
A
F
I
I
S
L
I
P
N
T
V
Y
G
W
I
I
V
E
I
A
C
I
P
I
L
L
L
S
L
R
R
G
L
T
A
G
L
V
G
G
L
I
W
G
I
L
S
M
I
T
G
H
A
Y
I
L
S
L
S
Q
A
F
L
E
Y
L
V
A
P
V
S
L
G
I
A
G
L
F
----
R
Q
K
T
A
P
L
K
L
A
P
V
L
---
L
G
T
F
-
V
A
V
L
L
K
Y
F
F
H
F
I
A
G
----
I
I
F
W
S
Q
Y
A
W
K
G
W
G
A
V
A
Y
S
L
A
V
N
G
I
S
G
I
L
T
A
I
A
A
F
V
I
L
I
I
F
V
K
K
F
P
K
L
F
I
----
14
PsiBlast_CBE
72.51
37%
-166
- C1 -
4MUU
15
?
B:
[17-188]
--
N
V
-
R
L
--
L
T
-----
E
I
A
F
M
A
A
L
A
F
I
I
S
L
I
P
N
T
V
Y
G
W
I
I
V
E
I
A
C
I
P
I
L
L
L
S
L
R
R
G
L
T
A
G
L
V
G
G
L
I
W
G
I
L
S
M
I
T
G
H
A
Y
I
L
S
L
S
Q
A
F
L
E
Y
L
V
A
P
V
S
L
G
I
A
G
L
F
----
R
Q
K
T
A
P
L
K
L
A
P
V
L
---
L
G
T
F
-
V
A
V
L
L
K
Y
F
F
H
F
I
A
G
----
I
I
F
W
S
Q
Y
A
W
K
G
W
G
A
V
A
Y
S
L
A
V
N
G
I
S
G
I
L
T
A
I
A
A
F
V
I
L
I
I
F
V
K
K
F
P
K
L
F
I
----
12
PsiBlast_CBE
72.46
37%
-163
- C1 -
4POV
12
THIT_LACLM
B:
[17-188]
--
N
V
-
R
L
--
L
T
-----
E
I
A
F
M
A
A
L
A
F
I
I
S
L
I
P
N
T
V
Y
G
W
I
I
V
E
I
A
C
I
P
I
L
L
L
S
L
R
R
G
L
T
A
G
L
V
G
G
L
I
W
G
I
L
S
M
I
T
G
H
A
Y
I
L
S
L
S
Q
A
F
L
E
Y
L
V
A
P
V
S
L
G
I
A
G
L
F
----
R
Q
K
T
A
P
L
K
L
A
P
V
L
---
L
G
T
F
-
V
A
V
L
L
K
Y
F
F
H
F
I
A
G
----
I
I
F
W
S
Q
Y
A
W
K
G
W
G
A
V
A
Y
S
L
A
V
N
G
I
S
G
I
L
T
A
I
A
A
F
V
I
L
I
I
F
V
K
K
F
P
K
L
F
I
----
3
PsiBlast_PDB
72.44
37%
-159
- C1 -
4N4D
19
?
A:
[7-178]
--
N
V
-
R
L
--
L
T
-----
E
I
A
F
M
A
A
L
A
F
I
I
S
L
I
P
N
T
V
Y
G
W
I
I
V
E
I
A
C
I
P
I
L
L
L
S
L
R
R
G
L
T
A
G
L
V
G
G
L
I
W
G
I
L
S
M
I
T
G
H
A
Y
I
L
S
L
S
Q
A
F
L
E
Y
L
V
A
P
V
S
L
G
I
A
G
L
F
----
R
Q
K
T
A
P
L
K
L
A
P
V
L
---
L
G
T
F
-
V
A
V
L
L
K
Y
F
F
H
F
I
A
G
----
I
I
F
W
S
Q
Y
A
W
K
G
W
G
A
V
A
Y
S
L
A
V
N
G
I
S
G
I
L
T
A
I
A
A
F
V
I
L
I
I
F
V
K
K
F
P
K
L
F
I
----
17
HHSearch
70.25
34%
-166
- C1 -
3RLB
8
?
A:
[17-189]
-----
N
V
R
L
L
T
-----
E
I
A
F
M
A
A
L
A
F
I
I
S
L
I
P
N
T
V
Y
G
W
I
I
V
E
I
A
C
I
P
I
L
L
L
S
L
R
R
G
L
T
A
G
L
V
G
G
L
I
W
G
I
L
S
M
I
T
G
H
A
Y
I
L
S
L
S
Q
A
F
L
E
Y
L
V
A
P
V
S
L
G
I
A
G
L
F
R
Q
K
T
A
P
L
--------
K
L
A
P
V
L
L
G
T
F
V
A
V
L
L
K
Y
F
F
H
F
I
A
G
----
I
I
F
W
S
Q
Y
A
W
K
G
W
G
A
V
A
Y
S
L
A
V
N
G
I
S
G
I
L
T
A
I
A
A
F
V
I
L
I
I
F
V
K
K
F
P
K
L
F
I
H
---
23
Fugue
69.73
34%
-163
* C1 *
3RLB
8
?
A:
[17-192]
-----
N
V
R
L
L
T
-----
E
I
A
F
M
A
A
L
A
F
I
I
S
L
I
P
N
T
V
Y
G
W
I
I
V
E
I
A
C
I
P
I
L
L
L
S
L
R
R
G
L
T
A
G
L
V
G
G
L
I
W
G
I
L
S
M
I
T
G
H
A
Y
I
L
S
L
S
Q
A
F
L
E
Y
L
V
A
P
V
S
L
G
I
A
G
L
F
R
Q
K
T
A
--------
P
L
K
L
A
P
V
L
L
G
T
F
V
A
V
L
L
K
Y
F
F
H
F
I
A
G
----
I
I
F
W
S
Q
Y
A
W
K
G
W
G
A
V
A
Y
S
L
A
V
N
G
I
S
G
I
L
T
A
I
A
A
F
V
I
L
I
I
F
V
K
K
F
P
K
L
F
I
H
S
NY
29
Fugue
55.45
19%
-145
- C1 -
3P5N
1
RIBU_STAAH
A:
[10-188]
Q
Q
N
K
-
R
L
I
T
I
S
-----
M
L
S
A
I
A
F
V
L
T
F
I
K
F
P
I
P
F
L
P
P
Y
L
T
L
D
F
S
D
V
P
S
L
L
A
T
F
T
F
G
P
V
A
G
I
I
V
A
L
V
K
N
L
L
N
Y
L
F
S
M
G
D
---
P
V
G
P
F
A
N
F
L
A
G
A
S
F
L
L
T
A
Y
A
I
Y
K
N
K
R
S
---
T
K
S
L
I
T
G
L
I
I
A
T
I
V
M
T
I
V
L
S
I
L
N
Y
F
V
L
L
-------
P
L
Y
G
M
K
V
I
I
V
S
G
I
I
P
F
N
I
I
K
G
I
V
I
S
I
V
F
I
L
L
Y
R
R
L
A
N
F
L
K
R
-----------
25
Fugue
54.61
22%
-219
- C1 -
1Q77
-
Y178_AQUAE
A:
[1-138]
-
S
N
A
M
K
V
L
L
V
L
T
DAYS
D
C
--
E
K
A
I
T
Y
A
V
N
F
S
E
---------
K
L
G
A
-
E
L
D
I
L
A
V
L
E
D
V
Y
N
L
E
R
A
N
V
T
F
G
L
P
F
----
P
P
E
I
K
E
E
S
K
K
R
I
E
R
R
L
R
E
V
W
E
K
L
T
G
------------
S
T
E
I
P
G
V
E
Y
R
-----
I
G
P
L
S
E
E
V
K
K
F
V
E
G
KGYE
L
V
V
W
A
C
Y
P
---------------
S
A
Y
L
C
K
V
I
D
G
L
N
L
A
S
L
I
V
K
-----------