@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1499: (2016-03-25 )
MKNTKGKKITIIISIIILILVIATFSGYYYVKSQLEPKDEASKEKITVEIPAGSSISDISTILEDKKVINNASIFSFYVKYNNDTNLKAGNYELSPAMNTDQIVKKMQEGKTVAPAKLVIPEGYTLDQIADRIVAYQPKLKKADVLKTMDDPEFVASMIKAYPETVTNDVLNKSIKHPLEGYLYPATYTFKGTDVSAEQIITEMVKATDVNIAKYRDELTKQKMSVHKFLTMSSIIEKEATENVDRKMIASVFYNRLAKDMRLQTDPTVLYALGEHKSKTTYKDLEVDSPYNTYKNNGLPPGPISNSGDSSMEAALYPEKSDYLYFLANTKTGKVYFSKTLEEHNKLKEEHITKNN
Atome Classification :
(20 SA)
---------------------------------.......-------------..--10...------.....-20.......---------.30..--------......40.....-....-50........---60.....-...------70-.-.-.....----..-------80-------....-..----..90-------.......-..100-.---..---..-------...-.110----------------....-.---..-..120.----------......130-..-----...----..140--------......-..150-.......--160-.....-.-..-170-.----...-...--.180....-.--.--.---------------190...-------..-.-.200.--....-..210....--..-...220..-......-230-.-.......240----...---.---------....250...-----------------.-...260....--------.-...270-...--.-...280.....--------.-...290....---.-..300---.........310--......---------------------------------.---.320.----------------......330-..----.....340.......350....-------------------
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
---------------------------------MKNTKG
K
-------------
K
I
--
T
I
I
I
S
------
I
I
I
L
I
-
L
V
I
A
TFS
G
Y
---------
Y
Y
V
KS--------QLEPKDE-ASK
E
K
-
I
T
V
E-IPAGSS
I
S
D
I
---
S
T
I
L
E
D
K
-
K
VI------N--N-A-
S
I
F
S
F
----
Y
V
-------
K
Y-------NNDT-NL----KAG--------
N
Y
E
LSPA-M
N
T
---
D
---
Q
I
---
V
K
-------
K
M
Q-EG------------------KTVA-
P
---
A
K
-
L
VIPEG----------Y
T
L
D
Q
I
A
D
R
-
I
V
-----AYQ----PKL
K
---------
K
A
D
V
L
K-TMD
D
P
-
E
F
V
A
S
M
I
--
K
A--Y
P
E
T
V
-
T
-
N
D
-
V
L
--
N
----
K
S
I-KHP--LE
G
Y
L
Y
P
A
-
T
--
Y
--
T
---------------FKGTDV-------
S
A
-
E
-
Q
I
I
T
E
--
M
V
K
A-TDV--
N
I
A
K
--
Y
R
-
D
E
L
T
K
-
Q
K
-
M
S
V
H
K
F
-
L
T
--
M
-
S
S
I
I
E
K
E
A
T-----E
N
V
---
D
---------
R
K
M
I
A
S
V
F
Y
N
-----------------
R
-
L
A
K
D
-MRLQT--------D-P
T
V
L
Y
A-LGE--H-KSKT--TY
K
D
L
--------E-VDSPYNTYKN---N-GLP-----PGPISNSGDSS---M
E
A
ALY---------------------------------P---EKS
D
Y
----------------
L
Y
F
L
ANTKT-
G
K
----
V
Y
F
S
K
T
L
E
E
H
N
K
L
K
E
E
HITKNN-------------------
1
PsiBlast_PDB
97.89
96%
-88
- C7 -
4IIW
5
?
A:
[35-342]
------------------------------------------------------------------------------------------------------------------
S
K
E
K
-
I
T
V
E
-
I
P
A
G
S
S
I
S
D
I
---
S
T
I
L
E
D
K
-
K
V
I
------
N
--
N
-
A
-
S
I
F
S
F
----
Y
V
-------
K
Y
-------
N
N
D
T
-
N
L
----
K
A
G
--------
N
Y
E
L
S
P
A
-
M
N
T
---
D
---
Q
I
---
V
K
-------
K
M
Q
-
E
G
------------------
K
T
V
A
-
P
---
A
K
-
L
V
I
P
E
G
----------
Y
T
L
D
Q
I
A
D
R
-
I
V
-----
A
Y
Q
----
P
K
L
K
---------
K
A
D
V
L
K
-
T
M
D
D
P
-
E
F
V
A
S
M
I
--
K
A
--
Y
P
E
T
V
-
T
-
N
D
-
V
L
--
N
----
K
S
I
-
K
H
P
--
L
E
G
Y
L
Y
P
A
-
T
--
Y
--
T
---------------
F
K
G
T
D
V
-------
S
A
-
E
-
Q
I
I
T
E
--
M
V
K
A
-
T
D
V
--
N
I
A
K
--
Y
R
-
D
E
L
T
K
-
Q
K
-
M
S
V
H
K
F
-
L
T
--
M
-
S
S
I
I
E
K
E
A
T
-----
E
N
V
---
D
---------
R
K
M
I
A
S
V
F
Y
N
-----------------
R
-
L
A
K
D
-
M
R
L
Q
T
--------
D
-
P
T
V
L
Y
A
-
L
G
E
--
H
-
K
S
K
T
--
T
Y
K
D
L
--------
E
-
V
D
S
P
Y
N
T
Y
K
N
---
N
-
G
L
P
-----
P
G
P
I
S
N
S
G
D
S
S
---
M
E
A
A
L
Y
---------------------------------
P
---
E
K
S
D
Y
----------------
L
Y
F
L
A
N
-----
K
----
V
Y
F
S
K
T
L
E
E
H
N
K
L
K
E
--------------------------
2
PsiBlast_PDB
69.46
34%
-42
- C7 -
2R1F
13
YCEG_ECOLI
A:
[11-261]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
F
----
K
A
G
--------
T
Y
R
F
T
P
Q
-
M
T
V
---
R
---
E
M
---
L
K
-------
L
L
E
-
S
G
------------------
K
E
A
Q
F
P
---
L
R
-
L
V
--
E
G
-----------------
M
R
-
L
S
-----
D
Y
L
----
K
Q
L
R
---------
E
A
P
Y
I
K
H
T
L
S
D
D
-
K
Y
-
A
T
V
A
--
Q
A
--
L
--------------------
E
L
-
E
N
P
EW
I
E
G
W
F
W
P
D
-
T
W
M
Y
--
T
---------------
A
N
T
T
D
V
-------
A
L
L
K
-
R
A
H
K
K
--
M
V
K
A
-
V
D
S
--
A
W
E
G
--
R
A
-
D
G
L
P
Y
-
K
D
-
K
N
--
Q
L
-
V
T
--
M
-
A
S
I
I
E
K
E
T
A
-----
V
A
S
---
E
---------
R
D
Q
V
A
S
V
F
I
N
-----------------
R
-
L
R
I
G
-
M
R
L
Q
T
--------
D
-
P
T
V
I
Y
G
-
M
G
E
R-
Y
-
N
G
K
L
--
S
R
A
D
L
--------
E
-
T
P
T
A
Y
N
T
Y
T
I
---
T
-
G
L
P
-----
P
G
A
I
A
T
P
G
A
D
S
---
L
K
A
A
A
H
---------------------------------
P
---
A
K
T
P
Y
----------------
L
Y
F
V
A
D
G
K
G
-
G
H
----
T
-
F
N
T
N
L
A
S
H
N
K
S
V
Q
D
Y
L
-----------------------
7
HHSearch
69.25
32%
-35
- C7 -
2R1F
13
YCEG_ECOLI
A:
[11-264]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
F
----
K
A
G
--------
T
Y
R
F
T
P
Q
-
M
T
V
---
R
---
E
M
---
L
K
-------
L
L
E
-
S
G
------------------
K
E
-
A
-
Q
---
F
P
-
L
R
L
V
E
G
----------
M
R
L
S
D
Y
L
K
Q
-
L
R
-----
E
-
A
----
P
Y
I
K
HTL------
S
D
D
K
Y
A
-
T
V
A
Q
A
--
L
------------
E
-------
L
----------
E
-
N
-
P
E
W
--
I
E
G
W
F
W
P
D
-
T
--
W
--
M
---------------
Y
T
A
-
N
T
-------
T
D
-
V
-
A
L
L
K
R
--
A
H
K
K
-
M
V
K
--
A
V
D
S
--
A
W
E
G
R
A
D
G
-
L
P
Y
K
D
K
N
Q
L
-
V
T
--
M
-
A
S
I
I
E
K
E
T
A
-----
V
A
S
---
E
---------
R
D
Q
V
A
S
V
F
I
N
-----------------
R
-
L
R
I
G
-
M
R
L
Q
T
--------
D
-
P
T
V
I
Y
G
-
M
G
E
--
R
Y
N
G
K
L
--
S
R
A
D
L
--------
E
-
T
P
T
A
Y
N
T
Y
T
I
---
T
-
G
L
P
-----
P
G
A
I
A
T
P
G
A
D
S
---
L
K
A
A
A
H
---------------------------------
P
---
A
K
T
P
Y
----------------
L
Y
F
V
A
D
-
G
K
-
G
G
----
H
T
F
N
T
N
L
A
S
H
N
K
S
V
Q
D
Y
L
K
V
L
--------------------
17
Fugue
61.51
30%
-18
- C7 -
2R1F
13
YCEG_ECOLI
A:
[11-270]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
H
F
----
K
A
G
--------
T
Y
R
F
T
P
Q
M
T
V
--------
R
E
M
--
L
K
-------
L
L
E
-
S
G
------------------
K
E
A
--
Q
---
F
P
-
L
R
L
V
E
G
M---------
R
L
S
D
Y
L
K
Q
L
-
R
E
-----
A
P
Y
----
I
K
-------------
H
T
L
S
-
D
D
K
Y
A
-
T
V
A
Q
A
L
----------------------
E
----
L
E
N
-
P
E
W
--
I
E
G
W
F
W
P
D
-
T
--
W
M
-
Y
---------------
T
A
N
T
---------
T
D
-
V
-
A
L
L
K
R
--
A
H
K
K
M
V
K
A
--
V
D
S
A
--
W
E
-
G
R
A
D
G
-
L
P
-
Y
K
D
K
N
Q
-
L
V
--
T
M
A
S
I
I
E
K
E
T
A
-----
V
A
S
---
E
---------
R
D
Q
V
A
S
V
F
I
N
-----------------
R
-
L
R
I
G
M
R
-
L
Q
T
--------
D
-
P
T
V
I
Y
G
M
G
E
R
--
Y
-
N
G
K
L
--
S
R
A
D
L
--------
E
-
T
P
T
A
Y
N
T
Y
T
I
---
T
-
G
L
P
-----
P
G
A
I
A
T
P
G
A
D
S
---
L
K
A
A
A
H
---------------------------------
P
---
A
K
T
P
Y
----------------
L
Y
F
V
A
D
-
G
K
-
G
G
----
H
T
F
N
T
N
L
A
S
H
N
K
S
V
Q
D
Y
L
K
V
L
K
E
K
NAQ--------------
24
Fugue
48.23
16%
2
- C6 -
3B7F
21
?
A:
[16-393]
---------------------------------
S
A
P
E
S
G
P
--------------------------------
V
M
L
L
V
A
T
I
K
G
A
---------
W
F
L
A
S
--------------
D
-
P
A
R
R
T
-
W
E
L
R
-
G
P
V
F
L
G
-
H
T
I
---
H
H
I
V
Q
D
P
-
R
E
P
------
E
--
R
M
L
M
A
A
R
T
L
G
P
T
V
F
R
-------
S
D
-------
D
G
G
G
-
N
W
----
T
E
A
--------
T
R
P
P
A
F
N
-
K
A
P
---
G
---
R
V
VDH
V
F
-------
W
L
T
-
P
G
------------------
H
A
S
E
-
P
G
T
W
Y
A
-
G
T
S
P
Q
G
----------
L
F
R
S
T
--
D
H
-
G
A
-----
S
W
E
----
P
---------------
V
A
G
-
F
N
D
H
P
M
R
--
R
A
W
T
--
G
G
--
E
P
D
G
P
-
K
M
H
S
-
I
L
V
D
P
----
R
D
P
-
K
H
-------
L
Y
I
G
M
S
--
S
G
G
V
---------------
F
E
S
T
D
A
-------
G
T
-
D
W
K
P
L
N
R
--
G
C
A
A
-
N
F
L
--
P
D
P
N
--
V
E
-
F
G
H
D
P
-
H
C
-
V
V
Q
H
P
---
A
--
A
-
P
D
I
L
Y
Q
Q
N
H
-----
C
G
I
Y
R
M
D
---------
R
R
---
E
G
V
W
K
-----------------
R
-
I
G
D
A
M
P
R
E
V
G
--------
D
-
I
G
F
P
I
V
-
V
H
Q
--
R
-
D
P
R
T
--
V
W
V
F
P
M
-------
D
-
G
S
D
V
W
P
R
V
S
P
---
G
-
G
K
P
-----
A
V
Y
V
T
R
D
A
G
E
S
W
Q
R
Q
D
R
G
L
P
---------------------------------
T
---
D
Q
A
W
L
T
V
K
RQA
M
T
A
D
AHAP
V
G
V
Y
F
G
--
T
T
G
-
G
E
----
I
W
A
S
A
D
E
G
E
H
W
Q
C
I
A
S
H
L
P
H
I
Y
A
V
Q
S
A
R
P------------
20
Fugue
47.88
16%
-10
* C4 *
4PEI
6
?
A:
[7-355]
-------------------------------------------------------------
Q
------
I
Q
H
I
A
-
I
V
G
S
V
H
G
K
Y
---------
R
E
M
Y
R
--------
Q
L
S
E
Y
E
K
-
S
T
G
K
E
-
I
S
F
V
-
I
C
T
G
----
D
M
---
Q
T
L
R
Y
E
A
-
D
L
V
YLKVPP
K
--
Y
-
K
-
Q
M
G
D
F
----
H
L
-------
Y
Y
-------
E
G
K
E
-
K
A
----
P
Y
L
--------
T
L
F
I
G
G
N
-
H
E
S
---
S
---
N
V
---
L
L
-------
H
L
Y
-
N
G
------------------
G
F
V
C
-
F
---
N
M
-
Y
Y
L
G
V
C
----------
S
C
I
N
I
N
G
L
R
-
I
V
-----
G
V
S
----
G
I
Y
K
---------
S
F
D
E
K
K
-
P
Y
T
Y
P
-
P
S
P
N
D
V
V
--
S
L
--
F
H
----
T
-
R
N
-
Y
V
--
I
----
Q
M
L
-
S
N
L
--
S
Q
S
-----------------------------
S
Q
I
D
I
-------
S
L
-
S
-
H
D
W
P
Q
G
I
V
M
K
G
-
N
Y
K
--
Q
L
Y
R
--
F
Q
-
P
G
F
K
K
-
D
G
-
A
S
---------
L
-
G
S
P
I
N
K
V
I
L
-----
N
T
L
---
K
---------
P
K
Y
W
I
S
G
H
M
H
---------------------
C
E
-
Y
H
A
E
E
--------
G
-
P
T
H
F
I
A
-
L
G
K
IG
Y
-
K
N
A
I
--
S
Y
L
D
L
P
L
K
Q
K
T
D
L
E
-
Y
D
K
D
W
V
C
N
L
I
M
T
W
P
-
A
F
S
-----
N
K
A
Q
F
P
D
L
S
Y
S
---
I
S
E
L
L
S
---------------------------------
K
RT
K
E
L
D
K
K
----------------
I
I
E
L
W
E
K
Y
I
-
G
L
KI--
I
Y
D
S
D
T
F
D
I
Q
F
T
S
R
R
F
Y
I
E
K
I
Y
N
E
L
NI--------------
22
Fugue
45.90
10%
-34
- C4 -
1DEA
2
NAGB_ECOLI
A:
[1-266]
---------------------------------------
M
-------------
R
L
--
I
P
L
T
T
------
A
E
Q
V
G
-
K
W
A
A
R
--------------
H
I
V
N
--------
R
I
N
A
F
K
P
-
T
A
D
R
P
-
F
V
L
G
-
L
P
T
G
G
T
P
M
T
T
---
Y
K
A
L
V
E
M
-
H
K
A
------
G
--
Q
-
V
-
S
F
K
H
V
----
V
T
-------
F
N
-------
M
D
E
Y
--------
V
G
--------
L
P
K
E
H
P
E
-
S
Y
Y
---
S
---
F
M
---
H
R
-------
N
F
F
-
D
H
------------------
V
D
I
P
-
A
---
E
N
-
I
N
L
L
N
G
-----------
N
A
P
D
I
D
A
E
-
C
R
-----
Q
Y
E
----
E
K
I
R
---------
S
Y
G
K
I
--------
H
L
F
M
G
G
V
--
G
N
--------------------------------
D
G
H
I
----
A
--
F
--
N
---------------
E
P
A
S
S
L
-------
A
S
-
R
-
T
R
I
K
T
--
L
T
H
D
-
T
R
V
--
A
N
S
R
--
F
F
-
D
N
D
V
N
-
Q
V
-
P
K
Y
A
L
T
-
V
G
--
V
-
G
T
L
L
D
---------------------------------------------------------------
A
--------
E
-
E
V
M
I
L
V
-
L
G
S
--
Q
-
K
A
L
A
--
L
Q
A
A
V
--------
E
-----------------------------
G
C
V
N
H
M
---
W
T
I
S
C
L
---------------------------------
Q
---
L
H
P
K
A
----------------
I
M
V
C
-
D
E
P
S
-
T
M
----
E
L
K
V
K
T
L
R
Y
F
N
E
L
E
A
E
N
I
K
G
L
--------------------
25
Fugue
44.40
16%
6
- C5 -
3W36
1
?
A:
[58-527]
--------IEFDLDKDN
Y
I
K
W
A
QPTDENAGQSP
T
L
A
I
L
G
P
-------------
M
D
--
V
T
V
F
L
------
W
I
N
R
V
-
V
W
L
A
A
F
D
A
L
A
PYHE
T
A
V
G
V
Y
S
Q
I
--------
P
R
R
P
S
S
E
S
A
T
N
R
N
-
L
N
I
A
A
L
H
A
Q
H
G
V
W
K
R
VLP
Q
Q
V
D
Q
L
R
-
E
L
M
------
T
--
A
-
L
-
G
L
D
P
S
----
D
E
-------
T
E
-------
N
L
S
S
-
P
V
----
G
I
G
--------
N
V
A
A
K
N
A
-
F
N
A
L
KN
D
---
G
M
---
N
F
-------
L
G
Y
-
E
G
------------------
R
K
Y
N
-
P
---
R
P
-
W
A
D
Y
T
G
----------
Y
E
P
V
N
T
A
F
K
-
V
N
NPS--
R
W
Q
----
P
Q
L
Q
---------
A
H
N
A
R
R
-
A
G
G
G
P
-
G
D
L
G
I
Y
V
--
T
Q
--
H
F
V
T
P
-
Q
-
T
A
-
R
T
--
K
----
A
H
I
F
R
D
P
--
S
R
F
R
I
P
R
P
-
E
--
F
--
S
---------------
D
H
T
N
T
R
-------
A
Y
-
K
-
R
S
V
D
E
--
I
I
D
A
-
S
A
N
LN
D
E
R
K
--
A
L
-
A
E
I
M
E
-
N
K
-
L
W
G
I
G
H
-
S
S
--
I
-
V
I
A
N
K
Y
D
Q
N
NEMG
V
H
G
W
---
C
---------
H
W
M
L
A
H
V
L
A
T
F
E
P
L
I
A
A
W
H
H
K
T
R
F
DAV
R
-
P
V
T
A
-
I
R
H
V
Y
--------
G
-
N
R
K
I
R
A
-
W
G
G
--
V
-
G
M
G
T
--
V
D
I
R
A
--------
S
-
E
W
S
S
Y
L
P
V
G
D
---
H
P
E
Y
P
-----
S
G
S
T
S
L
C
S
A
T
S
---
Q
A
A
R
R
Y
F
DSDELD
W
T
I
N
Y
P
A
GSTVVEPGITPG
K
D
L
S
I
H
I
P
---
T
W
T
D
F
----------------
T
R
T
C
A
T
S
R
V
W
G
G
----
V
H
F
Q
T
T
V
D
R
T
I
D
F
G
E
Q
F
G
D
L
A
H
E
F
V
Q
R
H
V
K
G----------
18
Fugue
44.29
16%
-3
- C4 -
5AHR
2
A:
[1-343]
--------------------------------S
M
T
C
P
F
Y
K
-------------
K
I
PG
T
G
F
T
V
------
D
A
F
Q
Y
-
G
V
V
E
G
C
T
A
Y
---------
F
L
T
H
F
--------
H
S
D
H
Y
A
G
-
L
S
K
H
F
----
T
-
F
P
V
Y
C
S
-
E
I
T
---
G
N
L
L
K
N
K
-
L
H
V
------
Q
--
E
-
Q
-
Y
I
H
P
L
-------------
P
L
-------
D
T
E
C
-
I
V
----
N
G
V
--------
K
V
V
L
L
D
A
-
N
H
C
---
P
G
A
V
M
I
---
L
F
-------
Y
L
P
-
N
G
------------------
T
V
I
L
-
H
---
T
G
------
D
----------
F
R
A
D
P
S
M
E
R
-
S
L
-----
L
A
D
----
Q
K
V
H
---------
M
L
Y
L
D
T
-
T
Y
C
S
P
-
E
Y
T
F
P
S
Q
--
Q
E
--
V
I
R
F
A
-
I
-
N
T
-
A
F
--
E
----
A
V
T
-
L
N
P
---
H
A
L
V
V
C
G
-
T
--
Y
--
S
--------------------
I
-------
G
K
-
E
-
K
V
F
L
A
--
I
A
D
V
-
L
G
S
--
K
V
G
---------------
M
S
Q
E
K
Y
-
K
T
--
L
-
Q
C
L
N
I
P
E
I
N
-----
S
L
I
---
T
---------
T
D
M
C
S
S
L
V
H
L
-----------------
L
-
P
M
M
Q
-
I
N
----------------
F
K
G
-
L
Q
S
--
H
-
L
K
K
C
GG
K
Y
N
Q
I
--------
L
-
A
F
R
P
T
V
I
P
Q
T
---
K
-
G
---------
N
I
S
I
Y
G
I
P
Y
---
S
E
H
S
S
Y
---------------------------------
L
---
E
M
K
R
F
----------------
V
Q
W
L
K
P
Q
K
I
-
I
P
----
T
V
N
V
G
T
W
K
S
R
S
T
M
E
K
Y
F
R
E
W
K
L
E
A
GY---------------
8
HHSearch
44.03
10%
-37
- C7 -
2R1F
8
YCEG_ECOLI
A:
[39-115]
---------------------------------------------------------------------------------------------------------------------
Q
-
F
P
L
R
-
L
V
E
G
M
R
L
S
D
Y
---
L
K
Q
L
R
E
A
-
P
Y
I
------
K
HT
L
-
S
-
D
D
K
Y
A
----
T
V
-------
A
Q
A
L
ELENP
E
W
I
E
G
W
F
----
W
P
D
--------
T
W
M
Y
T
A
N
-
T
T
D
---
V
---
A
L
---
L
K
-------
R
A
H
-
K
K
------------------
M
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
Fugue
42.84
19%
-13
- C2 -
4C9B
4
CWC22_HUMAN
B:
[8-291]
------------------------------------------------------------------------
D
-
P
L
L
T
R
T
G
G
A
---------
Y
I
P
P
A
--------
K
L
R
M
K
N
S
-
L
A
Y
Q
R
-
M
S
W
E
-
A
L
K
K
S
I
N
G
L
I
---
N
K
V
-----------------
N
-
I
-
S
N
I
S
I
----
I
I
-------
Q
E
-------
L
L
Q
E
-
N
I
----
V
R
G
-------------
R
G
-
L
L
S
---
R
---
S
V
---
L
Q
-------
A
Q
S
-
A
S
------------------
P
I
F
T
-
H
V
Y
-
A
A
-
L
V
A
I
I
N
----------
S
K
F
P
Q
I
G
E
L
-
I
L
K
R
L
I
L
N
F
R
----
K
G
Y
R
---------
R
N
D
K
Q
L
-
C
L
T
A
S
-
K
F
V
A
H
L
I
N
Q
N
V
--
A
H
E
V
L
-
C
-
L
E
-
M
L
--
T
----
L
L
L
-
E
R
P
------------------------------------
T
D
D
-------
S
V
-
E
--
V
A
I
G
--
F
L
K
E
-
C
G
L
--
K
L
T
Q
--
V
------
S
-
P
R
-
G
I
N
A
I
F
-
E
R
--
L
-
R
N
I
L
H
E
S
E
I
-----
D
K
R
---
V
---------
Q
Y
M
I
E
V
M
F
A
V
-----------------
R
-
K
D
G
F
-
K
D
H
P
I
--------
I
-
L
E
G
L
D
L
-
V
E
E
--
D
-
D
Q
F
T
--
H
M
L
P
L
--------
E
-------------------------------
D
D
Y
N
---
P
E
D
V
L
N
---------------------------------
V
---
F
K
M
D
P
---------------------------------
N
F
M
E
N
E
E
K
Y
K
A
I
K
K
E
I
L
-----------------------
26
Fugue
42.14
11%
-46
- C4 -
2PV7
3
TYRA_HAEIN
A:
[13-292]
-------------------------------------
G
F
K
-------------
T
I
--
N
S
D
I
H
------
K
I
V
I
V
-
G
G
Y
G
K
L
G
G
L
---------
F
A
R
Y
L
--------
R
-------------------
A
S
G
Y
P
I
S
I
L
D
R-
E
D
W
A
V
A
E
-
S
I
L
------
A
--
N
-
A
-
D
V
V
I
V
----
S
V
-------------------------------------------
P
I
-
N
L
T
---
L
---
E
T
---
I
E
-------
R
L
K
-
P
Y
---------------------
L
-
T
---
E
N
M
L
L
A
D
L
T
----------
S
V
K
R
E
P
L
A
K
M
L
E
-----
V
H
T
----
G
A
-------------------------
V
L
G
L
H
P
M-
F
G
--
A
D
I
A
S
M
A
-
K
Q
-
V
V
--
V
----
R
C
D
-
G
R
F
--
P
E
R
Y
---------------------------------------------
E
W
L
L
E
--
Q
I
Q
I
-
W
G
A
--
K
I
Y
Q
--
T
N
-
A
T
E
H
D
-
H
N
M
T
Y
I
Q
A
L
-
R
H
--
F
-
S
T
F
A
N
G
L
H
L
-----
S
K
Q
---
P
---------
I
N
--
L
A
N
L
L
A
-----------------
L
-
S
S
P
I
-
Y
R
L
E
L
--------
A
M
I
G
R
L
F
A
--------
Q
D
A
E
--
L
Y
A
D
I
--------
I
M
N
L
A
V
I
E
T
L
K
Q
---
T
-
Y
D
E
-----
A
L
T
F
F
E
N
N
D
R
Q
---
G
F
I
D
A
F
---------------------------------
H
---
K
V
R
D
W
----------------
F
-------------------
G
D
Y
S
E
Q
F
L
K
E
S
R
Q
L
L
Q
Q
A
-------------------
23
Fugue
41.91
16%
-6
* C5 *
4CZB
1
NAH1_METJA
A:
[1-415]
-------------M
E
L
M
M
A
I
G
Y
L
G
L
A
L
V
L
G
S
L
V
A
K
I
A
E
K
L
-------------
K
I
--
P
D
I
P
L
------
L
L
L
L
G
-
L
I
I
G
P
F
L
Q
I
---------
I
P
S
D
S
--------
A
M
E
I
F
E
Y
-
A
G
P
I
G
-
L
I
F
I
-
L
L
G
G
A
F
T
M
R
I
---
S
L
L
K
R
V
I
-
K
T
V
------
V
--
R
-
L
-
D
T
I
T
F
----
L
I
T
L
L
I
S
G
F
I
F
-------
N
M
V
L
-
N
L
PYTS
P
V
G
--------
Y
L
F
G
A
I
T
-
A
A
T
---
D
P--
A
T
---
L
I
-------
P
V
F
-
S
R
------------------
V
R
T
N
-
P
---
E
V
-
A
I
T
L
E
A
----------
E
S
I
F
N
D
P
L
G
-
I
V
-----
S
T
S
----
V
I
L
G
L
F
GLFSSSN
P
L
I
D
L
I
-
T
L
A
G
G
-
A
I
V
V
G
L
L
--
L
A
K
I
Y
E
K
I
I
-
I
-
H
C
-
D
F
--
H
----
E
Y
V
-
A
P
L
--
V
L
G
G
A
M
L
L
-
L
--
Y
--
V
G
DD
L
L
P
S
I
CG
Y
G
F
S
G
Y
M
A
V
A
I
-------
M
G
-
L
-
Y
L
G
D
A
--
L
F
R
A
-
D
D
I
--
D
Y
K
Y
--
I
V
-
S
F
C
D
D
-
L
S
-
L
L
A
R
V
F
-
I
F
V
F
L
-
G
A
C
I
K
L
S
M
L
-----
E
N
Y
---
F
---------
I
P
G
L
L
V
A
L
G
S
-----------------
I
F
L
A
R
P
-
L
G
V
F
L
G
L
I
GSKHS
F
-
K
E
K
L
Y
F
-
A
L
E
--
G
-
P
R
G
V
--
V
P
A
A
L
--------
A
-
V
T
V
G
I
E
I
L
K
N
---
A
-
D
K
I
-----
P
A
S
I
T
K
-------------
Y
---------------------------------
I
---
T
P
T
D
I
----------------
A
G
T
I
I
I
G
T
F
-
M
T
----
I
L
L
S
V
I
L
E
A
S
W
A
G
M
L
A
L
K
L
L
G
E
-------------------
21
Fugue
41.15
15%
-7
* C6 *
3WMT
7
FAEB1_ASPOR
A:
[18-522]
S
F
Q
A
E
C
E
S
FKAK
I
N
V
T
NANVH
S
V
T
Y
V
P
A
GVNIS
M
A
D
N
P
S
I
CGGDPITST
F
A
F
C
R
I
--
A
L
N
V
T
TSSK
S
Q
I
F
M
E
A
-
W
L
P
S
N
Y
S
G
R
---------
F
L
S
T
G
N
G
G
LGGCV
K
Y
D
D
M
A
Y
-
A
A
G
Y
G
F
A
T
V
G
-
T
N
N
G
H
F
G
N
N
G
---
V
S
F
Y
Q
N
T
-
E
V
V
------
E
--
D
-
F
-
A
Y
R
A
L
----
H
T
-------
G
V
-------
V
V
G
K
-
E
L
----
T
K
N
F
Y
P
QGYN
K
S
Y
Y
L
G
C
S
-
T
G
G
---
R
---
Q
G
---
W
K
-------
S
V
Q
-
T
F
PDDFD
G
V
V
A
G
APAFN
F
I
N
L
T
S
W
-
G
---
A
R
-
F
L
T
L
T
G
DSSAETFVT
E
T
Q
W
T
A
V
H
N
E
-
I
I
-----
R
Q
C
----
D
S
L
D
---------
G
A
K
D
-
G
-
I
I
E
D
P
-
D
L
C
Q
P
I
I
--
E
A
--
L
L
C
N
A
-
T
-
Q
S
-
S
T
--
S
GTCL
T
G
A
-
Q
V
K
--
T
V
N
G
V
F
S
A
-
T
--
Y
--
G
---------------
L
N
G
S
F
L
YPRMQPG
S
E
-
L
-
A
A
Y
S
S
--
Y
Y
S
G
-
T
P
F
--
A
Y
A
E
D
W
Y
R
-
Y
V
V
F
N
N
T
N
-
W
D
V
A
T
W
T
V
Q
--
D
-
A
A
I
A
N
A
Q
D
P
-----
Y
Q
I
---
S
TWNGDL
S
P
F
Q
K
K
G
G
K
V
L
H
Y
-----------------
H
-
G
M
E
D
-
A
I
I
S
S
--------
E
-
S
S
K
V
Y
--
Y
K
H
--
V
-
A
D
T
M
--
N
L
S
P
S
--------
E
-
L
D
S
F
Y
R
F
F
P
I
---
S
-
G
M
A
HCANA
D
G
P
S
A
I
G
Q
G
T
G
---
T
F
A
G
N
N
---------------------------------
P
---
Q
D
N
V
L
----------------
L
A
M
V
Q
W
V
E
E
-
G
V
APD
F
V
R
G
A
K
L
N
G
S
T
V
E
Y
R
R
K
H
C
K
Y
P
K
R
N
R
Y
V
G
PGSYTDENAWECV
16
HHSearch
39.09
11%
2
- C3 -
3RT3
1
ISG15_HUMAN
B:
[12-116]
-------------------------------------------------------------------------------------------------------------------
G
N
E
-
F
Q
V
S
-
L
S
S
S
M
S
V
S
E
L
---
K
A
Q
I
T
Q
K
I
G
V
H
------
A
--
F
-
Q
-
Q
R
L
A
V
----
H
P
-------
S
G
-------
V
A
L
Q
D
R
V
----
P
L
A
--------
S
Q
G
L
G
P
G
-
S
T
V
---
L
---
L
V
---
V
D
KSDEPLS
I
L
V
R
N
N
------------------
K
G
-
R
-
S
---
S
T
-
Y
E
V
R
L
T
----------
Q
T
V
A
H
L
K
Q
Q
-
V
S
-----
G
-
L
----
E
G
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
4
PsiBlast_PDB
30.10
38%
69
- C7 -
1WX1
-
COBT_THET8
A:
[24-82]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
----------
Y
-
L
E
E
V
A
L
R
-
L
A
-----
A
L
Q
GRV
K
P
E
L
G
---------
R
G
A
V
V
V
-
A
A
A
D
H
-
G
V
V
A
E
G
V
--
S
A
--
Y
P
Q
E
V
-
T
-
R
Q
M
V
L
--
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
28.26
38%
96
- C7 -
1J33
-
COBT_THET8
A:
[24-77]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
----------
Y
-
L
E
E
V
A
L
R
-
L
A
-----
A
L
Q
GRV
K
P
E
L
G
---------
R
G
A
V
V
V
-
A
A
A
D
H
-
G
V
V
A
E
G
V
--
S
A
--
Y
P
Q
E
V
-
T
-
R
Q
M
V
L
--
N
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
13
HHSearch
25.61
17%
577
* C7 *
1SPF
-
PSPC_PIG
A:
[8-19]
----------------------------------
V
N
L
K
R
L
-------------
L
V
--
V
V
V
V
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
11
HHSearch
21.20
18%
1128
- C1 -
2AFF
-
MK67I_HUMAN
B:
[232-242]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
-----
P
T
P
V
C
T
P
T
F
L
-----------------------------------------------------------------------------------------------------------------------------
5
PsiBlast_PDB
20.10
47%
114
- C7 -
4D10
-
CSN2_HUMAN
B:
[142-184]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
L
K
---------------------------------
D
---
A
K
N
D
R
----------------
L
W
F
K
T
N
T
K
L
-
G
K
----
L
Y
L
E
R
--
E
E
Y
G
K
L
Q
---------------------------