@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1544: (2016-03-26 )
MGEAIVITSGKGGVGKTTSTANLGTALALQGKKVCLIDMDIGLRNLDVVLGLENRIIYDLVDVVEGRCKIHQAMIKDKRFDDLLFLLPAAQTTDKNAVSGEQMVDLINQLRPDYDFILIDCPAGIETGYKNAVAGADKAIVVTTPEISAVRDADRIIGLLEKEDIEPPKLIINRIRTQMMMNGDVMDIDEITTHLSIELLGIIIDDDEVIRSSNSGDPVAMLPNNRASQGYRNIARRILGESIPLMSIETKKAGFFARLKQLFSGK
Atome Classification :
(21 SA)
.........10........20........30........40........50........60........70........80.....---...90....-....100.......110.--.......120.......130.......140.......150.......160---....--------...--------.---.170...-....180..-.....190....-------...200.......210......-.220-.......230.......240.......250..-.....260....
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MG
E
A
I
V
I
TSGKGGVGKTTSTANLG
T
A
L
ALQG
K
K
V
C
L
I
DMDIGL
R
N
L
D
V
V
LGLEN
R
I
I
Y
D
L
V
D
V
VE
G
R
C
K
I
H
Q
A
M
I
KDKRFD
D
L
L
F
L
---LPAAQTTDK-NAV
S
G
E
Q
M
V
D
L
I
N
Q
LR-P--DY
D
F
I
L
I
DCPAGIETGYKNAVAGAD
K
A
I
V
V
TTPE
I
S
A
VR
D
A
D
R
I
I
G
L
L
-----
E
KED--------IE
P
--------
P
---
K
L
I
I
N
R
I
-
R
T
Q
M
MMNGD-VM
D
I
D
E
I
T
T
H
L
S
-------
I
E
L
L
G
I
I
ID
D
D
E
V
IRSSNSGD
P
-
V
A
ML-PNNRA
S
Q
G
Y
R
N
I
A
R
R
I
LGESI
P
L
M
S
I
ETKK
A
G
-
F
F
A
R
L
K
Q
L
FSGK
115
Fugue
94.66
44%
-101
- C2 -
3Q9L
3
MIND_ECOLI
A:
[2-258]
-
A
R
I
I
V
V
T
S
G
K
G
G
V
G
K
T
T
S
S
A
A
I
A
T
G
L
A
Q
K
G
K
K
T
V
V
I
D
F
A
I
G
L
R
N
L
D
L
I
M
G
C
E
R
R
V
V
Y
D
F
V
N
V
I
Q
G
D
A
T
L
N
Q
A
L
I
K
D
K
R
T
E
N
-
L
Y
I
---
L
P
A
S
Q
T
R
D
K
-
D
A
L
T
R
E
G
V
A
K
V
L
D
D
L
K
A
M
--
D
F
E
F
I
V
C
D
S
P
A
G
I
E
T
G
A
L
M
A
L
Y
F
A
D
E
A
I
I
T
T
N
P
E
V
S
S
V
R
D
S
D
R
I
L
G
I
L
-----
A
S
K
S
--------
R
R
A
E
N
GEEPI
K
E
---
H
L
L
L
T
R
Y
-
N
P
G
R
V
S
R
G
D
-
M
L
S
M
E
D
V
L
E
I
L
R
-------
I
K
L
V
G
V
I
P
E
D
Q
S
V
L
R
A
S
N
Q
G
E
P
-
V
I
L
D
-
I
N
A
D
A
G
K
A
Y
A
D
T
V
E
R
L
L
G
E
E
R
P
F
R
F
I
E
E
-----------------
23
PsiBlast_CBE
94.64
44%
-110
- C2 -
3R9J
2
MIND_ECOLI
B:
[2-258]
-
A
R
I
I
V
V
T
S
G
K
G
G
V
G
K
T
T
S
S
A
A
I
A
T
G
L
A
Q
K
G
K
K
T
V
V
I
D
F
A
I
G
L
R
N
L
D
L
I
M
G
C
E
R
R
V
V
Y
D
F
V
N
V
I
Q
G
D
A
T
L
N
Q
A
L
I
K
D
K
R
T
E
N
-
L
Y
I
---
L
P
A
S
Q
T
R
D
K
-
D
A
L
T
R
E
G
V
A
K
V
L
D
D
L
K
-
A
M-
D
F
E
F
I
V
C
D
S
P
A
G
I
E
T
G
A
L
M
A
L
Y
F
A
D
E
A
I
I
T
T
N
P
E
V
S
S
V
R
D
S
D
R
I
L
G
I
L
ASKS---------------
E
--------
P
IKE
H
L
L
L
T
R
Y
-
N
P
G
R
V
S
R
G
D
-
M
L
S
M
E
D
V
L
E
I
L
R
-------
I
K
L
V
G
V
I
P
E
D
Q
S
V
L
R
A
S
N
Q
G
E
P
-
V
I
L
D
-
I
N
A
D
A
G
K
A
Y
A
D
T
V
E
R
L
L
G
E
E
R
P
F
R
F
I
E
E
-----------------
4
PsiBlast_PDB
94.64
44%
-105
- C2 -
3R9I
4
MIND_ECOLI
A:
[2-258]
-
A
R
I
I
V
V
T
S
G
K
G
G
V
G
K
T
T
S
S
A
A
I
A
T
G
L
A
Q
K
G
K
K
T
V
V
I
D
F
A
I
G
L
R
N
L
D
L
I
M
G
C
E
R
R
V
V
Y
D
F
V
N
V
I
Q
G
D
A
T
L
N
Q
A
L
I
K
D
K
R
T
E
N
-
L
Y
I
---
L
P
A
S
Q
T
R
D
K
-
D
A
L
T
R
E
G
V
A
K
V
L
D
D
L
K
-
A
M
-
D
F
E
F
I
V
C
D
S
P
A
G
I
E
T
G
A
L
M
A
L
Y
F
A
D
E
A
I
I
T
T
N
P
E
V
S
S
V
R
D
S
D
R
I
L
G
I
L
A
SKS
R
R
A
E
N
--------
G
E
E
--------
P
I
K
E
H
L
L
L
T
R
Y
-
N
P
G
R
V
S
R
G
D
-
M
L
S
M
E
D
V
L
E
I
L
R
-------
I
K
L
V
G
V
I
P
E
D
Q
S
V
L
R
A
S
N
Q
G
E
P
-
V
I
L
D
-
I
N
A
D
A
G
K
A
Y
A
D
T
V
E
R
L
L
G
E
E
R
P
F
R
F
I
E
E
-----------------
5
PsiBlast_PDB
94.48
44%
-110
- C2 -
3R9J
2
MIND_ECOLI
A:
[2-258]
-
A
R
I
I
V
V
T
S
G
K
G
G
V
G
K
T
T
S
S
A
A
I
A
T
G
L
A
Q
K
G
K
K
T
V
V
I
D
F
A
I
G
L
R
N
L
D
L
I
M
G
C
E
R
R
V
V
Y
D
F
V
N
V
I
Q
G
D
A
T
L
N
Q
A
L
I
K
D
K
R
T
E
N
-
L
Y
I
---
L
P
A
S
Q
T
R
D
K
-
D
A
L
T
R
E
G
V
A
K
V
L
D
D
L
K
-
A
M
-
D
F
E
F
I
V
C
D
S
P
A
G
I
E
T
G
A
L
M
A
L
Y
F
A
D
E
A
I
I
T
T
N
P
E
V
S
S
V
R
D
S
D
R
I
L
G
I
L
A
S---------------
G
E
E
--------
P
I
K
E
H
L
L
L
T
R
Y
-
N
P
G
R
V
S
R
G
D
-
M
L
S
M
E
D
V
L
E
I
L
R
-------
I
K
L
V
G
V
I
P
E
D
Q
S
V
L
R
A
S
N
Q
G
E
P
-
V
I
L
D
-
I
N
A
D
A
G
K
A
Y
A
D
T
V
E
R
L
L
G
E
E
R
P
F
R
F
I
E
E
-----------------
26
PsiBlast_CBE
94.33
44%
-108
- C2 -
3R9I
4
MIND_ECOLI
B:
[2-258]
-
A
R
I
I
V
V
T
S
G
K
G
G
V
G
K
T
T
S
S
A
A
I
A
T
G
L
A
Q
K
G
K
K
T
V
V
I
D
F
A
I
G
L
R
N
L
D
L
I
M
G
C
E
R
R
V
V
Y
D
F
V
N
V
I
Q
G
D
A
T
L
N
Q
A
L
I
K
D
K
R
T
E
N
-
L
Y
I
---
L
P
A
S
Q
T
R
----
A
L
T
R
E
G
V
A
K
V
L
D
D
L
K
-
A
M
-
D
F
E
F
I
V
C
D
S
P
A
G
I
E
T
G
A
L
M
A
L
Y
F
A
D
E
A
I
I
T
T
N
P
E
V
S
S
V
R
D
S
D
R
I
L
G
I
L
A
SKS
R
R
A
E
N
--------
G
E
E
--------
P
I
K
E
H
L
L
L
T
R
Y
-
N
P
G
R
V
S
R
G
D
-
M
L
S
M
E
D
V
L
E
I
L
R
-------
I
K
L
V
G
V
I
P
E
D
Q
S
V
L
R
A
S
N
Q
G
E
P
-
V
I
L
D
-
I
N
A
D
A
G
K
A
Y
A
D
T
V
E
R
L
L
G
E
E
R
P
F
R
F
I
E
E
-----------------
125
HHSearch
94.32
45%
-98
* C2 *
3Q9L
3
MIND_ECOLI
A:
[2-254]
-
A
R
I
I
V
V
T
S
G
K
G
G
V
G
K
T
T
S
S
A
A
I
A
T
G
L
A
Q
K
G
K
K
T
V
V
I
D
F
A
I
G
L
R
N
L
D
L
I
M
G
C
E
R
R
V
V
Y
D
F
V
N
V
I
Q
G
D
A
T
L
N
Q
A
L
I
K
D
K
R
T
E
N
-
L
Y
I
---
L
P
A
S
Q
T
R
D
K
-
D
A
L
T
R
E
G
V
A
K
V
L
D
D
L
K
A
M
--
D
F
E
F
I
V
C
D
S
P
A
G
I
E
T
G
A
L
M
A
L
Y
F
A
D
E
A
I
I
T
T
N
P
E
V
S
S
V
R
D
S
D
R
I
L
G
I
L
-----
A
S
K
S
R
R
A
E
N
GEE
P
I
K
--------
E
---
H
L
L
L
T
R
Y
-
N
P
G
R
V
S
R
G
D
-
M
L
S
M
E
D
V
L
E
I
L
R
-------
I
K
L
V
G
V
I
P
E
D
Q
S
V
L
R
A
S
N
Q
G
E
P
-
V
I
L
D
-
I
N
A
D
A
G
K
A
Y
A
D
T
V
E
R
L
L
G
E
E
R
P
F
R
---------------------
24
PsiBlast_CBE
93.94
44%
-106
- C2 -
3R9I
4
MIND_ECOLI
D:
[2-258]
-
A
R
I
I
V
V
T
S
G
K
G
G
V
G
K
T
T
S
S
A
A
I
A
T
G
L
A
Q
K
G
K
K
T
V
V
I
D
F
A
I
G
L
R
N
L
D
L
I
M
G
C
E
R
R
V
V
Y
D
F
V
N
V
I
Q
G
D
A
T
L
N
Q
A
L
I
K
D
K
R
T
E
N
-
L
Y
I
---
L
P
A
S
Q
T
R
D
K
-
D
A
L
T
R
E
G
V
A
K
V
L
D
D
L
K
-
A
M-
D
F
E
F
I
V
C
D
S
P
A
G
I
E
T
G
A
L
M
A
L
Y
F
A
D
E
A
I
I
T
T
N
P
E
V
S
S
V
R
D
S
D
R
I
L
G
I
L
ASKSR
R
A
E
N
--------
G
E
E
--------
P
IKE
H
L
L
L
T
R
Y
-
N
P
G
R
V
S
R
G
D
-
M
L
S
M
E
D
V
L
E
I
L
R
-------
I
K
L
V
G
V
I
P
E
D
Q
S
V
L
R
A
S
N
Q
G
E
P
-
V
I
L
D
-
I
N
A
D
A
G
K
A
Y
A
D
T
V
E
R
L
L
G
E
E
R
P
F
R
F
I
E
E
-----------------
3
PsiBlast_PDB
93.83
44%
-104
- C2 -
3Q9L
3
MIND_ECOLI
A:
[2-258]
-
A
R
I
I
V
V
T
S
G
K
G
G
V
G
K
T
T
S
S
A
A
I
A
T
G
L
A
Q
K
G
K
K
T
V
V
I
D
F
A
I
G
L
R
N
L
D
L
I
M
G
C
E
R
R
V
V
Y
D
F
V
N
V
I
Q
G
D
A
T
L
N
Q
A
L
I
K
D
K
R
T
E
N
-
L
Y
I
---
L
P
A
S
Q
T
R
D
K
-
D
A
L
T
R
E
G
V
A
K
V
L
D
D
L
K
-
A
M
-
D
F
E
F
I
V
C
D
S
P
A
G
I
E
T
G
A
L
M
A
L
Y
F
A
D
E
A
I
I
T
T
N
P
E
V
S
S
V
R
D
S
D
R
I
L
G
I
L
A
SKS
R
R
A
E
N
--------
G
E
E
--------
P
I
K
E
H
L
L
L
T
R
Y
-
N
P
G
R
V
S
R
G
D
-
M
L
S
M
E
D
V
L
E
I
L
R
-------
I
K
L
V
G
V
I
P
E
D
Q
S
V
L
R
A
S
N
Q
G
E
P
-
V
I
L
D
-
I
N
A
D
A
G
K
A
Y
A
D
T
V
E
R
L
L
G
E
E
R
P
F
R
F
I
E
E
-----------------
25
PsiBlast_CBE
93.67
44%
-110
- C2 -
3R9I
4
MIND_ECOLI
C:
[2-258]
-
A
R
I
I
V
V
T
S
G
K
G
G
V
G
K
T
T
S
S
A
A
I
A
T
G
L
A
Q
K
G
K
K
T
V
V
I
D
F
A
I
G
L
R
N
L
D
L
I
M
G
C
E
R
R
V
V
Y
D
F
V
N
V
I
Q
G
D
A
T
L
N
Q
A
L
I
K
D
K
R
T
E
N
-
L
Y
I
---
L
P
A
S
Q
T
R
----
A
L
T
R
E
G
V
A
K
V
L
D
D
L
K
-
A
M-
D
F
E
F
I
V
C
D
S
P
A
G
I
E
T
G
A
L
M
A
L
Y
F
A
D
E
A
I
I
T
T
N
P
E
V
S
S
V
R
D
S
D
R
I
L
G
I
L
ASKSR
R
A
E
N
--------
G
E
E
--------
P
IKE
H
L
L
L
T
R
Y
-
N
P
G
R
V
S
R
G
D
-
M
L
S
M
E
D
V
L
E
I
L
R
-------
I
K
L
V
G
V
I
P
E
D
Q
S
V
L
R
A
S
N
Q
G
E
P
-
V
I
L
D
-
I
N
A
D
A
G
K
A
Y
A
D
T
V
E
R
L
L
G
E
E
R
P
F
R
F
I
E
E
-----------------
27
PsiBlast_CBE
93.60
44%
-104
- C2 -
3Q9L
3
MIND_ECOLI
B:
[2-258]
-
A
R
I
I
V
V
T
S
G
K
G
G
V
G
K
T
T
S
S
A
A
I
A
T
G
L
A
Q
K
G
K
K
T
V
V
I
D
F
A
I
G
L
R
N
L
D
L
I
M
G
C
E
R
R
V
V
Y
D
F
V
N
V
I
Q
G
D
A
T
L
N
Q
A
L
I
K
D
K
R
T
E
N
-
L
Y
I
---
L
P
A
S
Q
T
R
D
K
-
D
A
L
T
R
E
G
V
A
K
V
L
D
D
L
K
-
A
M-
D
F
E
F
I
V
C
D
S
P
A
G
I
E
T
G
A
L
M
A
L
Y
F
A
D
E
A
I
I
T
T
N
P
E
V
S
S
V
R
D
S
D
R
I
L
G
I
L
ASKSR
R
A
E
N
--------
G
E
E
--------
P
IKE
H
L
L
L
T
R
Y
-
N
P
G
R
V
S
R
G
D
-
M
L
S
M
E
D
V
L
E
I
L
R
-------
I
K
L
V
G
V
I
P
E
D
Q
S
V
L
R
A
S
N
Q
G
E
P
-
V
I
L
D
-
I
N
A
D
A
G
K
A
Y
A
D
T
V
E
R
L
L
G
E
E
R
P
F
R
F
I
E
E
-----------------
1
PsiBlast_PDB
93.28
51%
-117
- C2 -
4V03
2
?
A:
[2-246]
-
A
E
V
I
V
I
T
S
G
K
G
G
V
G
K
T
T
L
T
A
N
I
G
T
A
L
A
K
L
G
K
K
V
L
L
I
D
A
D
---
R
N
L
D
M
I
L
G
L
E
N
R
I
V
Y
D
I
L
D
V
L
E
G
R
V
P
Y
E
K
A
L
V
K
D
K
R
G
L
S
L
-
W
L
---
L
P
---------
V
I
D
I
E
K
W
N
K
T
V
E
E
I
K
-
N
SG
N
Y
D
Y
I
L
V
D
S
P
A
G
I
E
K
G
F
Q
I
A
V
S
P
A
D
K
A
L
I
V
V
N
P
E
V
S
S
I
R
D
A
D
R
V
I
G
L
L
-----
E
S
M
D
--------
K
R
N
--------
Y
---
K
V
I
V
N
R
I
-
K
W
E
M
V
K
R
G
A
-
M
L
S
V
E
D
I
V
D
I
L
K
-------
A
E
I
I
G
I
I
P
E
E
P
K
L
V
D
F
T
N
R
G
E
P
-
I
V
L
D
-
E
K
F
P
A
S
Q
A
I
I
D
T
A
R
R
L
M
G
E
S
I
P
L
----------------------
2
PsiBlast_PDB
93.09
50%
-113
- C2 -
4V02
2
?
A:
[2-246]
-
A
E
V
I
V
I
T
S
G
K
G
G
V
G
K
T
T
L
T
A
N
I
G
T
A
L
A
K
L
G
K
K
V
L
L
I
D
A
A
I
G
L
R
N
L
D
M
I
L
G
L
E
N
R
I
V
Y
D
I
L
D
V
L
E
G
R
V
P
Y
E
K
A
L
V
K
D
K
R
G
L
S
L
-
W
L
---
L
P
A
-------
D
V
I
D
I
E
K
W
N
K
T
V
E
E
I
K
-
N
SG
N
Y
D
Y
I
L
V
D
S
P
A
G
I
E
K
G
F
Q
I
A
V
S
P
A
D
K
A
L
I
V
V
N
P
E
V
S
S
I
R
D
A
D
R
V
I
G
L
L
-----
E
S
M
D
--------
K
R
N
--------
Y
---
K
V
I
V
N
R
I
-
K
W
E
M
V
K
R
G
A
-
M
L
S
V
E
D
I
V
D
I
L
K
-------
A
E
I
I
G
I
I
P
E
E
P
K
L
V
D
F
T
N
R
G
E
P
-
I
V
L
D
-
E
K
F
P
A
S
Q
A
I
I
D
T
A
R
R
L
M
G
E
S
I
P
L
----------------------
21
PsiBlast_CBE
91.91
51%
-116
- C2 -
4V03
2
?
B:
[2-246]
-
A
E
V
I
V
I
T
S
G
K
G
G
V
G
K
T
T
L
T
A
N
I
G
T
A
L
A
K
L
G
K
K
V
L
L
I
D
A
D
---
R
N
L
D
M
I
L
G
L
E
N
R
I
V
Y
D
I
L
D
V
L
E
G
R
V
P
Y
E
K
A
L
V
K
D
K
R
G
L
S
L
-
W
L
---
L
P
A
--------
V
I
D
I
E
K
W
N
K
T
V
E
E
I
K
-
N
SG
N
Y
D
Y
I
L
V
D
S
P
A
G
I
E
K
G
F
Q
I
A
V
S
P
A
D
K
A
L
I
V
V
N
P
E
V
S
S
I
R
D
A
D
R
V
I
G
L
L
-----
E
S
M
D
--------
K
R
N
--------
Y
---
K
V
I
V
N
R
I
-
K
W
E
M
V
K
R
G
A
-
M
L
S
V
E
D
I
V
D
I
L
K
-------
A
E
I
I
G
I
I
P
E
E
P
K
L
V
D
F
T
N
R
G
E
P
-
I
V
L
D
-
E
K
F
P
A
S
Q
A
I
I
D
T
A
R
R
L
M
G
E
S
I
P
L
----------------------
22
PsiBlast_CBE
90.44
50%
-112
- C2 -
4V02
2
?
B:
[2-246]
-
A
E
V
I
V
I
T
S
G
K
G
G
V
G
K
T
T
L
T
A
N
I
G
T
A
L
A
K
L
G
K
K
V
L
L
I
D
A
A
I
G
L
R
N
L
D
M
I
L
G
L
E
N
R
I
V
Y
D
I
L
D
V
L
E
G
R
V
P
Y
E
K
A
L
V
K
D
K
R
G
L
S
L
-
W
L
---
L
P
A
--------
V
I
D
I
E
K
W
N
K
T
V
E
E
I
K
-
N
SG
N
Y
D
Y
I
L
V
D
S
P
A
G
I
E
K
G
F
Q
I
A
V
S
P
A
D
K
A
L
I
V
V
N
P
E
V
S
S
I
R
D
A
D
R
V
I
G
L
L
-----
E
S
M
D
--------
K
R
N
--------
Y
---
K
V
I
V
N
R
I
-
K
W
E
M
V
K
R
G
A
-
M
L
S
V
E
D
I
V
D
I
L
K
-------
A
E
I
I
G
I
I
P
E
E
P
K
L
V
D
F
T
N
R
G
E
P
-
I
V
L
D
-
E
K
F
P
A
S
Q
A
I
I
D
T
A
R
R
L
M
G
E
S
I
P
L
----------------------
127
HHSearch
77.54
31%
-102
- C2 -
1G3Q
2
?
A:
[1-236]
M
G
R
I
I
S
I
V
S
G
K
G
G
T
G
K
T
T
V
T
A
N
L
S
V
A
L
G
D
R
G
R
K
V
L
A
V
D
G
D
L
T
M
A
N
L
S
L
V
L
G
V
D
D
P
D
-
V
T
L
H
D
V
L
A
G
E
A
N
V
E
D
A
I
Y
M
T
-
Q
F
D
N
-
V
Y
V
---
L
P
G
A
V
D
W
E
H
V
L
K
A
D
P
R
K
L
P
E
V
I
K
S
L
K
-
D
--
K
F
D
F
I
L
I
D
C
P
A
G
L
Q
L
D
A
M
S
A
M
L
S
G
E
E
A
L
L
V
T
N
P
E
I
S
C
L
T
D
T
M
K
V
G
I
V
L
-----
K
K
A
G
--------
L
A
I
--------
L
---
G
F
V
L
N
R
Y
-
G
R
S
D
R
D
-----
I
P
P
E
A
A
E
D
V
M
E
-------
V
P
L
L
A
V
I
P
E
D
P
A
I
R
E
G
T
L
E
G
I
P
-
A
V
K
Y
K
P
E
S
K
G
A
K
A
F
V
K
L
A
E
E
I
E
K
L
--------------------------
8
PsiBlast_PDB
76.94
31%
-101
- C2 -
1G3R
2
?
A:
[1-233]
M
G
R
I
I
S
I
V
S
G
K
G
G
T
G
K
T
T
V
T
A
N
L
S
V
A
L
G
D
R
G
R
K
V
L
A
V
D
G
D
L
T
M
A
N
L
S
L
V
L
G
V
D
D
P
D
V
T
-
L
H
D
V
L
A
G
E
A
N
V
E
D
A
-
I
Y
M
T
Q
F
D
N
V
Y
V
L
---
P
G
A
V
D
W
E
H
V
-
L
K
A
D
P
R
K
L
P
E
V
I
K
S
L
K
-
D
--
K
F
D
F
I
L
I
D
C
P
A
G
L
Q
L
D
A
M
S
A
M
L
S
G
E
E
A
L
L
V
T
N
P
E
I
S
C
L
T
D
T
M
K
V
G
I
V
L
-----
K
K
A
G
--------
L
A
I
--------
L
---
G
F
V
L
N
R
Y
G
R
S
D
R
D
I
P
P
E
-
A
A
E
-----
D
V
M
E
-------
V
P
L
L
A
V
I
P
E
D
P
A
I
R
E
G
T
L
E
G
I
P
A
V
K
Y
K
-
P
E
S
K
G
A
K
A
F
V
K
L
A
E
E
I
-----------------------------
7
PsiBlast_PDB
76.68
31%
-102
- C2 -
1G3Q
2
?
A:
[1-233]
M
G
R
I
I
S
I
V
S
G
K
G
G
T
G
K
T
T
V
T
A
N
L
S
V
A
L
G
D
R
G
R
K
V
L
A
V
D
G
D
L
T
M
A
N
L
S
L
V
L
G
V
D
D
P
D
V
T
-
L
H
D
V
L
A
G
E
A
N
V
E
D
A
-
I
Y
M
T
Q
F
D
N
V
Y
V
L
---
P
G
A
V
D
W
E
H
V
-
L
K
A
D
P
R
K
L
P
E
V
I
K
S
L
K
-
D
--
K
F
D
F
I
L
I
D
C
P
A
G
L
Q
L
D
A
M
S
A
M
L
S
G
E
E
A
L
L
V
T
N
P
E
I
S
C
L
T
D
T
M
K
V
G
I
V
L
-----
K
K
A
G
--------
L
A
I
--------
L
---
G
F
V
L
N
R
Y
G
R
S
D
R
D
I
P
P
E
-
A
A
E
-----
D
V
M
E
-------
V
P
L
L
A
V
I
P
E
D
P
A
I
R
E
G
T
L
E
G
I
P
A
V
K
Y
K
-
P
E
S
K
G
A
K
A
F
V
K
L
A
E
E
I
-----------------------------
10
PsiBlast_PDB
76.45
30%
-105
- C2 -
4RZ2
-
?
A:
[33-292]
----
I
A
V
T
S
G
K
G
G
V
G
K
S
N
V
S
L
N
F
S
L
S
L
S
K
L
G
F
R
V
L
L
L
D
M
D
I
G
M
G
N
I
D
I
L
L
G
E
S
S
S
L
A
--
L
A
D
W
F
S
A
R
L
P
L
S
E
-
L
V
K
S
G
P
-
E
H
L
S
Y
I
A
G
G
T
G
A
A
Q
W
Q
G
L
-
D
T
A
S
I
D
R
F
L
T
E
L
Q
A
V
A
-
S
--
Q
Y
D
Y
L
I
F
D
M
G
A
G
A
S
G
E
R
L
Y
F
L
K
S
V
D
D
V
F
V
V
T
T
P
E
P
T
A
M
T
D
A
Y
A
M
M
K
Y
M
-----
H
A
A
G
--------
S
E
A
--------
P
F
--
S
V
I
V
N
R
A
-
G
K
E
R
----
E
-
G
Y
E
V
F
E
R
L
K
H
V
T
G
R
FLN
K
D
I
A
L
L
G
I
I
P
E
D
R
T
V
A
R
A
V
V
S
Q
T
P
-
F
V
L
L
D
P
A
A
K
A
S
K
A
V
R
Q
M
A
F
R
Y
----
A
P
----------R
F
F
A
K
L
R
Q
L
F
---
124
HHSearch
75.88
33%
-97
- C2 -
1HYQ
-
?
A:
[2-233]
-
V
R
T
I
T
V
A
S
G
K
G
G
T
G
K
T
T
I
T
A
N
L
G
V
A
L
A
Q
L
G
H
D
V
T
I
V
D
A
D
I
T
M
A
N
L
E
L
I
L
G
M
E
G
L
P
-
V
T
L
Q
N
V
L
A
G
E
A
R
I
D
E
A
I
Y
V
--
G
P
G
G
-
V
K
V
---
V
P
A
G
V
S
L
E
G
L
R
K
A
N
P
E
K
L
E
D
V
L
T
Q
I
M
-
E
--
S
T
D
I
L
L
L
D
A
P
A
G
L
E
R
S
A
V
I
A
I
A
A
A
Q
E
L
L
L
V
V
N
P
E
I
S
S
I
T
D
G
L
K
T
K
I
V
A
-----
E
R
L
G
--------
T
K
V
--------
L
---
G
V
V
V
N
R
I
-
T
T
L
G
I
E
-----
M
A
K
N
E
I
E
A
I
L
E
-------
A
K
V
I
G
L
I
P
E
D
P
E
V
R
R
A
A
A
Y
G
K
P
-
V
V
L
R
S
P
N
S
P
A
A
R
A
I
V
E
L
A
N
Y
I
A
----------------------------
9
PsiBlast_PDB
74.85
32%
-98
- C2 -
1ION
2
?
A:
[5-233]
----
I
S
I
V
S
G
K
G
G
T
G
K
T
T
V
T
A
N
L
S
V
A
L
G
E
M
G
R
K
V
L
A
V
D
G
D
L
T
M
A
N
L
S
L
V
L
G
V
D
D
V
N
I
-
T
L
H
D
V
L
A
G
D
A
K
L
E
D
A
-
I
Y
M
T
Q
F
E
N
V
Y
I
L
---
P
G
A
V
D
W
E
H
V
-
I
K
A
D
P
R
K
L
P
E
V
I
K
S
L
K
-
G
--
K
Y
D
F
I
L
I
D
C
P
A
G
L
Q
L
R
A
M
S
A
M
L
S
G
E
E
A
I
L
V
T
N
P
E
I
S
C
L
T
D
T
M
K
V
G
M
V
L
-----
K
K
A
G
--------
L
A
I
--------
L
---
G
F
I
L
N
R
Y
G
R
S
E
R
D
I
P
P
E
A
A
Q
D
V
M
D
V
P
-------------
L
L
A
V
I
P
E
D
P
V
I
R
E
G
T
L
E
G
I
P
A
V
K
Y
K
-
P
E
S
K
G
A
Q
A
F
I
K
L
A
E
E
V
-----------------------------
11
PsiBlast_PDB
74.14
30%
-98
- C2 -
4RZ3
2
?
A:
[33-272]
----
I
A
V
T
S
G
K
G
G
V
G
K
S
N
V
S
L
N
F
S
L
S
L
S
K
L
G
F
R
V
L
L
L
D
M
A
I
G
M
G
N
I
D
I
L
L
G
E
S
S
S
L
A
--
L
A
D
W
F
S
A
R
L
P
L
S
E
-
L
V
K
S
G
P
-
E
H
L
S
Y
I
A
GG
T
G
A
A
Q
W
Q
G
L
-
D
T
A
S
I
D
R
F
L
T
E
L
Q
A
V
A
-
S
--
Q
Y
D
Y
L
I
F
D
M
G
A
G
A
S
G
E
R
L
Y
F
L
K
S
V
D
D
V
F
V
V
T
T
P
E
P
T
A
M
T
D
A
Y
A
M
M
K
Y
M
-----
H
A
A
G
--------
S
E
A
--------
P
F
--
S
V
I
V
N
R
A
-
G
K
E
R
----
E
-
G
Y
E
V
F
E
R
L
K
H
V
T
G
R
F
LN
K
D
I
A
L
L
G
I
I
P
E
D
R
T
V
A
R
A
V
V
S
Q
T
P
-
F
V
L
L
D
P
A
A
K
A
S
K
A
V
R
Q
M
A
F
R
Y
----
A
P
-----------------------