@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1565: (2016-03-26 )
VNKLVLIDGNSIANRAFYALPLLNNDKGVYTNAVYGFAMMLMNVLEKEKPSHVLVAFDAGKTTFRHTTFKGYKGGRQKTPSELSEQFPFIRELLTAYDIPQYELANYEADDIIGTLTKKAEADGMEVAIITGDRDLTQLASEKTTVYITKKGIADMETNTPETLKEKYNLTPEQIIDMKGLMGDSSDNIPGIPGVGEKTALKLLHEFGGTVESVLEHAEEISGKKLKEKVLENKELAILSKELATINVDSPIECTVESTKYDGYQTEKVIPLLKEMNFTTLLKNIEGDTPEESKELKELSFEIVTELKEQHFGGKTALYVELENDNYHTANFIGLTVHSSQGTYFFTKETAESSEAFRKWVESDQTKVVYDAKKTIVAMNRIGLAISGITFDIMLASYLLNPSDSIDDFTSVAVRHDYTEVETDEAVYGKGAKRSTPEESIVAAHLARKAVAIADLEKRLVDDLEKNEQLALMEDLELPLTFVLAEMEMQGVSVDTDRLEDMKVELGGRLKTLEASIHSLAGEEFNINSPKQLGVILFEKLELPPVKKTKTGYSTAADVLESLSGKHAIIDEILLYRQLGKIQSTYIEGLLKVTDKETHKVHTRFNQTLTQTGRLSSVDPNLQNIPIRLEEGRKIRQVFVPSKPGWKMFSADYSQVELRVLAHISEDENLIYAFKHDYDIHTKTAMDVFHVEKEEVDSLMRRQAKAVNFGIVYGISDYGLSQNLGITRKEAKDFIDRYFVSYPAVKEYMQDIVRFAKEKGYVETILHRRRYIPEIVSRNFNVRGFAERTAMNTPIQGSAADIIKKAMILMSERLVSEKLEAKLLLQVHDELIFEAPEAEIAKLEEIVPDVMENAVELSVPLKVDSAFGDTWYDAK
Atome Classification :
(93 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.....--..370........380.......390.......400..---.....410.......420---.......430.......440.......450.......460.......470........480.......490.......500.......510.......520.......530.......540.......-550-.......560.......570.......580.......590.......600...---....610.......620...---....630.------.....----.640.......650.......660.......670.......680.......690.......700.......710.......720.......730.......740.......750.......760.......770.......780.......790.......800.......810...-.--------...820..-----------.....830.......840.......850..-------.....860.......870...----
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
V
N
K
L
V
L
IDGNSIANR
A
F
Y
A
LPLLNNDKGV
Y
T
N
A
V
Y
G
F
A
M
M
L
M
N
V
L
E
KEKPS
H
V
L
V
A
FDAGK
T
T
F
R
HTTFKGYKGGRQK
T
P
S
E
L
S
E
Q
F
P
F
I
R
E
L
L
T
AYDIP
Q
Y
E
LANY
E
A
D
D
I
I
G
T
L
T
K
KAEADG
M
E
V
A
I
I
TGD
R
D
L
T
Q
LASEK
T
T
V
Y
I
TKKGIADMETN
T
P
E
T
L
K
E
K
YNL
T
P
E
Q
I
I
D
M
K
GLMGDSSDNIPGIPGV
G
E
K
T
A
L
K
L
L
H
E
FG
G
T
V
E
S
V
L
E
H
A
E
E
IS
G
K
K
L
K
E
K
V
LENK
E
L
A
I
L
S
K
E
L
A
T
I
NVDS
P
I
E
C
T
V
ESTKYDGY
Q
T
E
K
V
I
P
L
L
K
EM
N
F
T
T
L
L
K
NIEGDT
P
E
E
S
K
E
L
K
E
L
S
F
E
I
V
T
E
L
K
E
QHFGG
K
T
A
L
Y
V
E
LENDNY
H
T
A
N
F
I
G
L
T
V
HSSQ
G
T
Y
F
F
TKETA
E
S
S
E
A
F
R
K
W
V
ESDQ
T
K
--
V
V
Y
D-A
K
K
T
I
V
A
MNRI
G
L
A
ISG
I
T
F
D
I
M
L
A
S
Y
LLNPSD---SI
D
D
F
T
S
V
A
V
RHDYTEVE---TDEAVYGKGAKRSTP
E
E
S
I
V
A
A
H
L
A
R
K
A
V
A
I
A
D
L
E
K
R
L
V
D
D
L
EKNE
Q
L
-
A
L
M
E
DLEL
P
L
T
F
V
L
A
E
M
EMQGVSV
D
T
D
R
L
E
D
M
K
V
E
LGGR
L
K
T
L
E
A
S
I
H
S
LAGEEFNIN
S
P
K
Q
L
G
V
I
L
F
E
KLELPPVKKT-KTG-YS
T
A
A
D
V
L
E
S
LSG
K
H
A
I
I
D
E
I
L
L
Y
R
Q
L
G
K
I
Q
S
T
Y
I
E
G
L
L
K
VTDKE
T
H
K
V
H
T
R
F
---
N
Q
T
L
TQTGRLSSVDPNLQNI---
P
I
R
LEEG
R
------
K
I
R
Q
V
----FVPSKPG
W
K
M
FSAD
Y
S
Q
V
E
L
R
V
L
A
HISEDE
N
L
I
Y
A
F
KHDYDIHT
K
T
A
M
D
V
F
HV
E
K
E
E
V
D
S
L
M
R
R
Q
A
KAV
N
F
G
I
V
Y
GISDYGLSQNLGI
T
R
K
E
A
K
D
F
I
D
R
Y
F
VS
Y
P
A
V
K
E
Y
M
Q
D
I
V
R
F
A
K
EK
G
Y
V
E
T
I
L
H
R
R
R
Y
I
P
E
I
V
SRNFNV
R
G
F
AERTAMNTPIQG
S
A
A
D
I
I
K
K
A
M
I
L
M
S
E
R
L
V
-
S
--------
E
K
L
E
A
K
L
L
-----------
L
Q
V
H
D
E
L
IFEAP
E
A
E
I
A
K
L
E
E
I
V
P
D
V
M
ENA-------
V
E
L
S
V
P
L
K
V
DSAFGDTWYDAK----
93
PsiBlast_CBE
95.74
61%
-93
- C4 -
3HT3
5
?
A:
[1-579]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
M
A
F
T
L
A
D
R
V
T
E
E
M
L
A
D
K
A
A
L
V
V
E
V
V
E
E
N
Y
H
D
A
P
I
V
G
I
A
V
V
N
E
H
G
R
F
F
L
R
P
E
T
A
L
A
D
P
Q
F
V
A
W
L
-
G
D
E
T
K
K
K
S
M
F
D
-
S
K
R
A
A
V
A
L
K
W
K
G
I
E
L
C
G
V
S
F
D
L
L
L
A
A
Y
L
L
D
P
A
Q
---
G
V
D
D
V
A
A
A
A
K
M
K
Q
Y
E
A
V
R
---
P
D
E
A
V
Y
G
K
G
A
K
R
A
V
P
D
E
P
V
L
A
E
H
L
V
R
K
A
A
A
I
W
E
L
E
R
P
F
L
D
E
L
R
R
N
E
Q
D
-
R
L
L
V
E
L
E
Q
P
L
S
S
I
L
A
E
M
E
F
A
G
V
K
V
D
T
K
R
L
E
Q
M
G
K
E
L
A
E
Q
L
G
T
V
E
Q
R
I
Y
E
L
A
G
Q
E
F
N
I
N
S
P
K
Q
L
G
V
I
L
F
E
K
L
Q
L
P
V
L
K
K
T
-
K
T
G
-
Y
S
T
S
A
D
V
L
E
K
L
A
P
Y
H
E
I
V
E
N
I
L
H
Y
R
Q
L
G
K
L
Q
S
T
Y
I
E
G
L
L
K
V
V
R
P
A
T
K
K
V
H
T
I
F
---
N
Q
A
L
T
Q
T
G
R
L
S
S
T
E
P
N
L
Q
N
I
---
P
I
R
L
E
E
G
R
------
K
I
R
Q
A
----
F
V
P
S
E
S
D
W
L
I
F
A
A
D
Y
S
Q
I
E
L
R
V
L
A
H
I
A
E
D
D
N
L
M
E
A
F
R
R
D
L
D
I
H
T
K
T
A
M
D
I
F
Q
V
S
E
D
E
V
T
P
N
M
R
R
Q
A
K
A
V
N
F
G
I
P
Y
G
I
S
D
Y
G
L
A
Q
N
L
N
I
S
R
K
E
A
A
E
F
I
E
R
Y
F
E
S
F
P
G
V
K
R
Y
M
E
N
I
V
Q
E
A
K
Q
K
G
Y
V
T
T
L
L
H
R
R
R
Y
L
P
D
I
T
S
R
N
F
N
V
R
S
F
A
E
R
M
A
M
N
T
P
I
Q
G
S
A
A
D
I
I
K
K
A
M
I
D
L
N
A
R
L
K
-
E
--------
E
R
L
Q
A
H
L
L
-----------
L
Q
V
H
D
E
L
I
L
E
A
P
K
E
E
M
E
R
L
C
R
L
V
P
E
V
M
E
Q
A
-------
V
T
L
R
V
P
L
K
V
D
Y
H
Y
G
S
T
W
Y
D
A
K
----
92
PsiBlast_CBE
95.56
61%
-92
- C4 -
3HT3
8
?
D:
[1-579]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
M
A
F
T
L
A
D
R
V
T
E
E
M
L
A
D
K
A
A
L
V
V
E
V
V
E
E
N
Y
H
D
A
P
I
V
G
I
A
V
V
N
E
H
G
R
F
F
L
R
P
E
T
A
L
A
D
P
Q
F
V
A
W
L
-
G
D
E
T
K
KK
S
M
F
D
-
S
K
R
A
A
V
A
L
K
W
K
G
I
E
L
C
G
V
S
F
D
L
L
L
A
A
Y
L
L
D
P
A
Q
---
G
V
D
D
V
A
A
A
A
K
M
K
Q
Y
E
A
V
R
---
P
D
E
A
V
Y
G
K
G
A
K
R
A
V
P
D
E
P
V
L
A
E
H
L
V
R
K
A
A
A
I
W
E
L
E
R
P
F
L
D
E
L
R
R
N
E
Q
D
-
R
L
L
V
E
L
E
Q
P
L
S
S
I
L
A
E
M
E
F
A
G
V
K
V
D
T
K
R
L
E
Q
M
G
K
E
L
A
E
Q
L
G
T
V
E
Q
R
I
Y
E
L
A
G
Q
E
F
N
I
N
S
P
K
Q
L
G
V
I
L
F
E
K
L
Q
L
P
V
L
K
K
T
-
K
T
G
-
Y
S
T
S
A
D
V
L
E
K
L
A
P
Y
H
E
I
V
E
N
I
L
H
Y
R
Q
L
G
K
L
Q
S
T
Y
I
E
G
L
L
K
V
V
R
P
A
T
K
K
V
H
T
I
F
---
N
Q
A
L
T
Q
T
G
R
L
S
S
T
E
P
N
L
Q
N
I
---
P
I
R
L
E
E
G
R
------
K
I
R
Q
A
----
F
V
P
S
E
S
D
W
L
I
F
A
A
D
Y
S
Q
I
E
L
R
V
L
A
H
I
A
E
D
D
N
L
M
E
A
F
R
R
D
L
D
I
H
T
K
T
A
M
D
I
F
Q
V
S
E
D
E
V
T
P
N
M
R
R
Q
A
K
A
V
N
F
G
I
P
Y
G
I
S
D
Y
G
L
A
Q
N
L
N
I
S
R
K
E
A
A
E
F
I
E
R
Y
F
E
S
F
P
G
V
K
R
Y
M
E
N
I
V
Q
E
A
K
Q
K
G
Y
V
T
T
L
L
H
R
R
R
Y
L
P
D
I
T
S
R
N
F
N
V
R
S
F
A
E
R
M
A
M
N
T
P
I
Q
G
S
A
A
D
I
I
K
K
A
M
I
D
L
N
A
R
L
K
-
E
--------
E
R
L
Q
A
H
L
L
-----------
L
Q
V
H
D
E
L
I
L
E
A
P
K
E
E
M
E
R
L
C
R
L
V
P
E
V
M
E
Q
A
-------
V
T
L
R
V
P
L
K
V
D
Y
H
Y
G
S
T
W
Y
D
A
K
----
75
PsiBlast_CBE
95.56
61%
-94
- C4 -
1L5U
8
DPO1_GEOSE
A:
[2-580]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
M
A
F
T
L
A
D
R
V
T
E
E
M
L
A
D
K
A
A
L
V
V
E
V
V
E
E
N
Y
H
D
A
P
I
V
G
I
A
V
V
N
E
H
G
R
F
F
L
R
P
E
T
A
L
A
D
P
Q
F
V
A
W
L
-
G
D
E
T
K
K
K
S
M
F
D
-
S
K
R
A
A
V
A
L
K
W
K
G
I
E
L
C
G
V
S
F
D
L
L
L
A
A
Y
L
L
D
P
A
Q
---
G
V
D
D
V
A
A
A
A
K
M
K
Q
Y
E
A
V
R
---
P
D
E
A
V
Y
G
K
G
A
K
R
A
V
P
D
E
P
V
L
A
E
H
L
V
R
K
A
A
A
I
W
E
L
E
R
P
F
L
D
E
L
R
R
N
E
Q
D
-
R
L
L
V
E
L
E
Q
P
L
S
S
I
L
A
E
M
E
F
A
G
V
K
V
D
T
K
R
L
E
Q
M
G
K
E
L
A
E
Q
L
G
T
V
E
Q
R
I
Y
E
L
A
G
Q
E
F
N
I
N
S
P
K
Q
L
G
V
I
L
F
E
K
L
Q
L
P
V
L
K
K
T
-
K
T
G
-
Y
S
T
S
A
D
V
L
E
K
L
A
P
Y
H
E
I
V
E
N
I
L
H
Y
R
Q
L
G
K
L
Q
S
T
Y
I
E
G
L
L
K
V
V
R
P
D
T
K
K
V
H
T
I
F
---
N
Q
A
L
T
Q
T
G
R
L
S
S
T
E
P
N
L
Q
N
I
---
P
I
R
L
E
E
G
R
------
K
I
R
Q
A
----
F
V
P
S
E
S
D
W
L
I
F
A
A
D
Y
S
Q
I
E
L
R
V
L
A
H
I
A
E
D
D
N
L
M
E
A
F
R
R
D
L
D
I
H
T
K
T
A
M
D
I
F
Q
V
S
E
D
E
V
T
P
N
M
R
R
Q
A
K
A
V
N
F
G
I
V
Y
G
I
S
D
Y
G
L
A
Q
N
L
N
I
S
R
K
E
A
A
E
F
I
E
R
Y
F
E
S
F
P
G
V
K
R
Y
M
E
N
I
V
Q
E
A
K
Q
K
G
Y
V
T
T
L
L
H
R
R
R
Y
L
P
D
I
T
S
R
N
F
N
V
R
S
F
A
E
R
M
A
M
N
T
P
I
Q
G
S
A
A
D
I
I
K
K
A
M
I
D
L
N
A
R
L
K
-
E
--------
E
R
L
Q
A
H
L
L
-----------
L
Q
V
H
D
E
L
I
L
E
A
P
K
E
E
M
E
R
L
C
R
L
V
P
E
V
M
E
Q
A
-------
V
T
L
R
V
P
L
K
V
D
Y
H
Y
G
S
T
W
Y
D
A
K
----
10
PsiBlast_PDB
95.52
61%
-96
- C4 -
2XY6
6
?
A:
[3-581]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
M
A
F
T
L
A
D
R
V
T
E
E
M
L
A
D
K
A
A
L
V
V
E
V
V
E
E
N
Y
H
D
A
P
I
V
G
I
A
V
V
N
E
H
G
R
F
F
L
R
P
E
T
A
L
A
D
P
Q
F
V
A
W
L
-
G
D
E
T
K
K
K
S
M
F
D
-
S
K
R
A
A
V
A
L
K
W
K
G
I
E
L
C
G
V
S
F
D
L
L
L
A
A
Y
L
L
D
P
A
Q
---
G
V
D
D
V
A
A
A
A
K
M
K
Q
Y
E
A
V
R
---
P
D
E
A
V
Y
G
K
G
A
K
R
A
V
P
D
E
P
V
L
A
E
H
L
V
R
K
A
A
A
I
W
A
L
E
R
P
F
L
D
E
L
R
R
N
E
Q
D
-
R
L
L
V
E
L
E
Q
P
L
S
S
I
L
A
E
M
E
F
A
G
V
K
V
D
T
K
R
L
E
Q
M
G
E
E
L
A
E
Q
L
R
T
V
E
Q
R
I
Y
E
L
A
G
Q
E
F
N
I
N
S
P
K
Q
L
G
V
I
L
F
E
K
L
Q
L
P
V
L
K
K
S
-
K
T
G
-
Y
S
T
S
A
D
V
L
E
K
L
A
P
Y
H
E
I
V
E
N
I
L
H
Y
R
Q
L
G
K
L
Q
S
T
Y
I
E
G
L
L
K
V
V
R
P
D
T
K
K
V
H
T
I
F
---
N
Q
A
L
T
Q
T
G
R
L
S
S
T
E
P
N
L
Q
N
I
---
P
I
R
L
E
E
G
R
------
K
I
R
Q
A
----
F
V
P
S
E
S
D
W
L
I
F
A
A
D
Y
S
Q
I
E
L
R
V
L
A
H
I
A
E
D
D
N
L
M
E
A
F
R
R
D
L
D
I
H
T
K
T
A
M
D
I
F
Q
V
S
E
D
E
V
T
P
N
M
R
R
Q
A
K
A
V
N
F
G
I
V
Y
G
I
S
D
Y
G
L
A
Q
N
L
N
I
S
R
K
E
A
A
E
F
I
E
R
Y
F
E
S
F
P
G
V
K
R
Y
M
E
N
I
V
Q
E
A
K
Q
K
G
Y
V
T
T
L
L
H
R
R
R
Y
L
P
D
I
T
S
R
N
F
N
V
R
S
F
A
E
R
M
A
M
N
T
P
I
Q
G
S
A
A
D
I
I
K
K
A
M
I
D
L
N
A
R
L
K
-
E
--------
E
R
L
Q
A
R
L
L
-----------
L
Q
V
H
D
E
L
I
L
E
A
P
K
E
E
M
E
R
L
C
R
L
V
P
E
V
M
E
Q
A
-------
V
T
L
R
V
P
L
K
V
D
Y
H
Y
G
S
T
W
Y
D
A
K
----
62
PsiBlast_CBE
95.45
61%
-92
- C4 -
1NKC
7
DPO1_GEOSE
A:
[2-580]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
M
A
F
T
L
A
D
R
V
T
E
E
M
L
A
D
K
A
A
L
V
V
E
V
V
E
E
N
Y
H
D
A
P
I
V
G
I
A
V
V
N
E
H
G
R
F
F
L
R
P
E
T
A
L
A
D
P
Q
F
V
A
W
L
-
G
D
E
T
K
K
K
S
M
F
D
-
S
K
R
A
A
V
A
L
K
W
K
G
I
E
L
C
G
V
S
F
D
L
L
L
A
A
Y
L
L
D
P
A
Q
---
G
V
D
D
V
A
A
A
A
K
M
K
Q
Y
E
A
V
R
---
P
D
E
A
V
Y
G
K
G
A
K
R
A
V
P
D
E
P
V
L
A
E
H
L
V
R
K
A
A
A
I
W
E
L
E
R
P
F
L
D
E
L
R
R
N
E
Q
D
-
R
L
L
V
E
L
E
Q
P
L
S
S
I
L
A
E
M
E
F
A
G
V
K
V
D
T
K
R
L
E
Q
M
G
K
E
L
A
E
Q
L
G
T
V
E
Q
R
I
Y
E
L
A
G
Q
E
F
N
I
N
S
P
K
Q
L
G
V
I
L
F
E
K
L
Q
L
P
V
L
K
K
T
-
K
T
G
-
Y
S
T
S
A
D
V
L
E
K
L
A
P
Y
H
E
I
V
E
N
I
L
H
Y
R
Q
L
G
K
L
Q
S
T
Y
I
E
G
L
L
K
V
V
R
P
D
T
K
K
V
H
T
I
F
---
N
Q
A
L
T
Q
T
G
R
L
S
S
T
E
P
N
L
Q
N
I
---
P
I
R
L
E
E
G
R
------
K
I
R
Q
A
----
F
V
P
S
E
S
D
W
L
I
F
A
A
D
Y
S
Q
I
E
L
R
V
L
A
H
I
A
E
D
D
N
L
M
E
A
F
R
R
D
L
D
I
H
T
K
T
A
M
D
I
F
Q
V
S
E
D
E
V
T
P
N
M
R
R
Q
A
K
A
V
N
F
G
I
V
Y
G
I
S
D
Y
G
L
A
Q
N
L
N
I
S
R
K
E
A
A
E
F
I
E
R
Y
F
E
S
F
P
G
V
K
R
Y
M
E
N
I
V
Q
E
A
K
Q
K
G
Y
V
T
T
L
L
H
R
R
R
Y
L
P
D
I
T
S
R
N
F
N
V
R
S
F
A
E
R
M
A
M
N
T
P
I
Q
G
S
A
A
D
I
I
K
K
A
M
I
D
L
N
A
R
L
K
-
E
--------
E
R
L
Q
A
H
L
L
-----------
L
Q
V
H
D
E
L
I
L
E
A
P
K
E
E
M
E
R
L
C
R
L
V
P
E
V
M
E
Q
A
-------
V
T
L
R
V
P
L
K
V
D
Y
H
Y
G
S
T
W
Y
D
A
K
----
46
PsiBlast_CBE
95.39
61%
-94
- C4 -
1U4B
8
DPO1_GEOSE
A:
[3-580]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
M
A
F
T
L
A
D
R
V
T
E
E
M
L
A
D
K
A
A
L
V
V
E
V
V
E
E
N
Y
H
D
A
P
I
V
G
I
A
V
V
N
E
H
G
R
F
F
L
R
P
E
T
A
L
A
D
P
Q
F
V
A
W
L
-
G
D
E
T
K
K
K
S
M
F
D
-
S
K
R
A
A
V
A
L
K
W
K
G
I
E
L
C
G
V
S
F
D
L
L
L
A
A
Y
L
L
D
P
A
Q
---
G
V
D
D
V
A
A
A
A
K
M
K
Q
Y
E
A
V
R
---
P
D
E
A
V
Y
G
K
G
A
K
R
A
V
P
D
E
P
V
L
A
E
H
L
V
R
K
A
A
A
I
W
E
L
E
R
P
F
L
D
E
L
R
R
N
E
Q
D
-
R
L
L
V
E
L
E
Q
P
L
S
S
I
L
A
E
M
E
F
A
G
V
K
V
D
T
K
R
L
E
Q
M
G
K
E
L
A
E
Q
L
G
T
V
E
Q
R
I
Y
E
L
A
G
Q
E
F
N
I
N
S
P
K
Q
L
G
V
I
L
F
E
K
L
Q
L
P
V
L
K
K
T
-
K
T
G
-
Y
S
T
S
A
D
V
L
E
K
L
A
P
Y
H
E
I
V
E
N
I
L
H
Y
R
Q
L
G
K
L
Q
S
T
Y
I
E
G
L
L
K
V
V
R
P
D
T
K
K
V
H
T
I
F
---
N
Q
A
L
T
Q
T
G
R
L
S
S
T
E
P
N
L
Q
N
I
---
P
I
R
L
E
E
G
R
------
K
I
R
Q
A
----
F
V
P
S
E
S
D
W
L
I
F
A
A
D
Y
S
Q
I
E
L
R
V
L
A
H
I
A
E
D
D
N
L
M
E
A
F
R
R
D
L
D
I
H
T
K
T
A
M
D
I
F
Q
V
S
E
D
E
V
T
P
N
M
R
R
Q
A
K
A
V
N
F
G
I
V
Y
G
I
S
D
Y
G
L
A
Q
N
L
N
I
S
R
K
E
A
A
E
F
I
E
R
Y
F
E
S
F
P
G
V
K
R
Y
M
E
N
I
V
Q
E
A
K
Q
K
G
Y
V
T
T
L
L
H
R
R
R
Y
L
P
D
I
T
S
R
N
F
N
V
R
S
F
A
E
R
M
A
M
N
T
P
I
Q
G
S
A
A
D
I
I
K
K
A
M
I
D
L
N
A
R
L
K
-
E
--------
E
R
L
Q
A
H
L
L
-----------
L
Q
V
H
D
E
L
I
L
E
A
P
K
E
E
M
E
R
L
C
R
L
V
P
E
V
M
E
Q
A
-------
V
T
L
R
V
P
L
K
V
D
Y
H
Y
G
S
T
W
Y
D
A
K
----
18
PsiBlast_PDB
95.38
61%
-95
- C4 -
4UQG
7
?
A:
[1-579]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
M
A
F
T
L
A
D
R
V
T
E
E
M
L
A
D
K
A
A
L
V
V
E
V
V
E
E
N
Y
H
D
A
P
I
V
G
I
A
V
V
N
E
H
G
R
F
F
L
R
P
E
T
A
L
A
D
P
Q
F
V
A
W
L
-
G
D
E
T
K
K
K
S
M
F
D
-
S
K
R
A
A
V
A
L
K
W
K
G
I
E
L
C
G
V
S
F
D
L
L
L
A
A
Y
L
L
D
P
A
Q
---
G
V
D
D
V
A
A
A
A
K
M
K
Q
Y
E
A
V
R
---
P
D
E
A
V
Y
G
K
G
A
K
R
A
V
P
D
E
P
V
L
A
E
H
L
V
R
K
A
A
A
I
W
A
L
E
R
P
F
L
D
E
L
R
R
N
E
Q
D
-
R
L
L
V
E
L
E
Q
P
L
S
S
I
L
A
E
M
E
F
A
G
V
K
V
D
T
K
R
L
E
Q
M
G
E
E
L
A
E
Q
L
R
T
V
E
Q
R
I
Y
E
L
A
G
Q
E
F
N
I
N
S
P
K
Q
L
G
V
I
L
F
E
K
L
Q
L
P
V
L
K
K
S
-
K
T
G
-
Y
S
T
S
A
D
V
L
E
K
L
A
P
Y
H
E
I
V
E
N
I
L
H
Y
R
Q
L
G
K
L
Q
S
T
Y
I
E
G
L
L
K
V
V
R
P
D
T
K
K
V
H
T
I
F
---
N
Q
A
L
T
Q
T
G
R
L
S
S
T
E
P
N
L
Q
N
I
---
P
I
R
L
E
E
G
R
------
K
I
R
Q
A
----
F
V
P
S
E
S
D
W
L
I
F
A
A
D
Y
S
Q
I
E
L
R
V
L
A
H
I
A
E
D
D
N
L
M
E
A
F
R
R
D
L
D
I
H
T
K
T
A
M
D
I
F
Q
V
S
E
D
E
V
T
P
N
M
R
R
Q
A
K
A
V
N
F
G
I
V
Y
G
I
S
D
Y
G
L
A
Q
N
L
N
I
S
R
K
E
A
A
E
F
I
E
R
Y
F
E
S
F
P
G
V
K
R
Y
M
E
N
I
V
Q
E
A
K
Q
K
G
Y
V
T
T
L
L
H
R
R
R
Y
L
P
D
I
T
S
R
N
F
N
V
R
S
F
A
E
R
M
A
M
N
T
P
I
Q
G
S
A
A
D
I
I
K
K
A
M
I
D
L
N
A
R
L
K
-
E
--------
E
R
L
Q
A
R
L
L
-----------
L
Q
V
H
D
E
L
I
L
E
A
P
K
E
E
M
E
R
L
C
R
L
V
P
E
V
M
E
Q
A
-------
V
T
L
R
V
P
L
K
V
D
Y
H
Y
G
S
T
W
Y
D
A
K
----
63
PsiBlast_CBE
95.37
61%
-94
- C4 -
1NKB
8
DPO1_GEOSE
A:
[2-580]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
M
A
F
T
L
A
D
R
V
T
E
E
M
L
A
D
K
A
A
L
V
V
E
V
V
E
E
N
Y
H
D
A
P
I
V
G
I
A
V
V
N
E
H
G
R
F
F
L
R
P
E
T
A
L
A
D
P
Q
F
V
A
W
L
-
G
D
E
T
K
K
K
S
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---
G
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---
P
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---
N
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P
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K
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A
----
F
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E
--------
E
R
L
Q
A
H
L
L
-----------
L
Q
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H
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L
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L
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A
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K
E
E
M
E
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L
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A
-------
V
T
L
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Y
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A
K
----