@TOME V2.3
(Nov 2016)
Ref.
-
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Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1589: (2016-03-26 )
VENTIVIKLGGVASDNLTEGFFRQITEWQAANKKIVLVHGGGHYITKMMEALAIPVETKNGLRVTNKATLEVTKMVLIGQVQPAITTAFQKRNISVIGLNASDTGLLEADRLSDTDLGLVGKITKVKTNLIEQLLSENIITVIAPLGINSEHDWLNVNADTAACEVASALHAEALYLLTDVPGVKNGSEIIGEIATAEIEKLQSTGVIKGGMIPKLASAAFAAENGVGQVIITDSLNNSGTKIKNKVAIG
Atome Classification :
(36 SA)
.........10.--.--.--..---..--.20........30..-..-.....40........50........60........70........80........90........100.......110-----...------------....120.......130.......140.......150.......160.......170.......180..----....----.190.......200.......210.......220.......230..-....------------.240.......250---
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
VE
N
T
I
V
I
K
LGGV--A--S--DN---L
T
--
E
G
F
F
R
Q
I
T
E
W
QA-AN-
K
K
-
I
V
L
V
HGG
G
H
Y
I
T
K
M
M
E
A
LAI
P
V
ETKN
G
L
R
VT
N
K
A
T
L
E
V
T
K
M
V
L
IGQV
Q
P
A
I
T
T
A
F
QKR
N
I
S
V
I
G
LNASDTGLLEADRL-----SDT------------DLGL
V
G
K
I
T
K
V
K
T
N
L
I
E
Q
L
L
SEN
I
I
T
V
I
A
PLGINSEH
D
W
L
N
VNAD
T
A
A
C
E
V
A
S
A
L
H
A
E
A
L
Y
L
L
TDVPGV----K
N
G
S
----
E
I
I
G
E
I
A
T
A
E
I
E
K
L
Q
STGVIKGGMI
P
K
L
A
S
A
A
F
AAENGV
G
Q
V
I
I
TD-SLNN------------SG
T
K
I
K
N
K
VAIG-----
57
HHSearch
92.52
39%
-115
- C1 -
3L86
3
ARGB_STRMU
A:
[36-279]
-
K
D
I
I
V
I
K
I
G
G
V
--
A
--
S
--
Q
Q
---
L
S
--
G
D
F
L
S
Q
I
K
N
W
Q
D
-
A
G
-
K
Q
-
L
V
I
V
H
G
G
G
F
A
I
N
K
L
M
E
E
N
Q
V
P
V
K
K
I
N
G
L
R
V
T
S
K
D
D
M
V
L
V
S
H
A
L
L
D
L
V
G
K
N
L
Q
E
K
L
R
Q
A
G
V
S
C
Q
Q
L
K
S
D
I
K
H
V
V
A
A
D
Y
L
-----
D
K
D
------------
T
Y
G
Y
V
G
D
V
T
H
I
N
K
R
V
I
E
E
F
L
E
N
R
Q
I
P
I
L
A
S
L
G
Y
S
K
E
G
D
M
L
N
I
N
A
D
Y
L
A
T
A
V
A
V
A
L
A
A
D
K
L
I
L
M
T
N
V
K
G
V
----
L
E
N
G
----
A
V
L
E
K
I
T
S
H
Q
V
Q
E
K
I
D
T
A
V
I
T
A
G
M
I
P
K
I
E
S
A
A
K
T
V
A
A
G
V
G
Q
V
L
I
G
D
-
N
L
L
-------------
T
G
T
L
I
T
A
D
---------
32
PsiBlast_CBE
91.27
38%
-122
- C1 -
2BUF
1
ARGB_PSEAE
C:
[25-273]
V
G
K
T
L
V
I
K
Y
G
G
N
--
A
ME
S
--
E
E
---
L
K
--
A
G
F
A
R
D
V
V
L
M
K
A
-
V
G
-
I
N
-
P
V
V
V
H
G
G
G
P
Q
I
G
D
L
L
K
R
L
S
I
E
S
H
F
I
D
G
M
R
V
T
D
A
A
T
M
D
V
V
E
M
V
L
G
G
Q
V
N
K
D
I
V
N
L
I
N
R
H
G
G
S
A
I
G
L
T
G
K
D
A
E
L
I
R
A
K
K
L
-----
T
V
T
R
QTPEMTK
P
E
I
I
D
I
G
H
V
G
E
V
T
G
V
N
V
G
L
L
N
M
L
V
K
G
D
F
I
P
V
I
A
P
I
G
V
G
S
N
G
E
S
Y
N
I
N
A
D
L
V
A
G
K
V
A
E
A
L
K
A
E
K
L
M
L
L
T
N
I
A
G
L
MD--
K
Q
G
Q
----
V
L
T
G
-
L
S
T
E
Q
V
N
E
L
I
A
D
G
T
I
Y
G
G
M
L
P
K
I
R
C
A
L
E
A
V
Q
G
G
V
T
S
A
H
I
I
D
----------------------------------
23
PsiBlast_CBE
90.99
38%
-119
- C1 -
2BUF
22
ARGB_PSEAE
L:
[25-273]
V
G
K
T
L
V
I
K
Y
G
G
N
--
A
ME
S
--
E
E
---
L
K
--
A
G
F
A
R
D
V
V
L
M
K
A
-
V
G
-
I
N
-
P
V
V
V
H
G
G
G
P
Q
I
G
D
L
L
K
R
L
S
I
E
S
H
F
I
D
G
M
R
V
T
D
A
A
T
M
D
V
V
E
M
V
L
G
G
Q
V
N
K
D
I
V
N
L
I
N
R
H
G
G
S
A
I
G
L
T
G
K
D
A
E
L
I
R
A
K
K
L
-----
T
V
T
RQKPEII-----
D
I
G
H
V
G
E
V
T
G
V
N
V
G
L
L
N
M
L
V
K
G
D
F
I
P
V
I
A
P
I
G
V
G
S
N
G
E
S
Y
N
I
N
A
D
L
V
A
G
K
V
A
E
A
L
K
A
E
K
L
M
L
L
T
N
I
A
G
L
MD--
K
Q
G
Q
----
V
L
T
G
-
L
S
T
E
Q
V
N
E
L
I
A
D
G
T
I
Y
G
G
M
L
P
K
I
R
C
A
L
E
A
V
Q
G
G
V
T
S
A
H
I
I
D
----------------------------------
58
HHSearch
90.92
38%
-111
- C1 -
2BTY
3
ARGB_THEMA
A:
[20-280]
Y
G
K
T
F
V
I
K
F
G
G
S
--
A
--
M
--
K
Q
---
E
N
A
K
K
A
F
I
Q
D
I
I
L
L
K
Y
-
T
G
-
I
K
-
P
I
I
V
H
G
G
G
P
A
I
S
Q
M
M
K
D
L
G
I
E
P
V
F
K
N
G
H
R
V
T
D
E
K
T
M
E
I
V
E
M
V
L
V
G
K
I
N
K
E
I
V
M
N
L
N
L
H
G
G
R
A
V
G
I
C
G
K
D
S
K
L
I
V
A
E
K
E
T----
K
H
G
------------
D
I
G
Y
V
G
K
V
K
K
V
N
P
E
I
L
H
A
L
I
E
N
D
Y
I
P
V
I
A
P
V
G
I
G
E
D
G
H
S
Y
N
I
N
A
D
T
A
A
A
E
I
A
K
S
L
M
A
E
K
L
I
L
L
T
D
V
D
G
V
----
L
K
D
G
----
K
L
I
S
T
L
T
P
D
E
A
E
E
L
I
R
D
G
T
V
T
G
G
M
I
P
K
V
E
C
A
V
S
A
V
R
G
G
V
G
A
V
H
I
I
N
-
G
G
L
E
H
A
I
L
L
E
I
F
SRKG
I
G
T
M
I
K
E
L
---------
31
PsiBlast_CBE
90.84
38%
-121
- C1 -
2BUF
1
ARGB_PSEAE
D:
[25-273]
V
G
K
T
L
V
I
K
Y
G
G
N
--
A
ME
S
--
E
E
---
L
K
--
A
G
F
A
R
D
V
V
L
M
K
A
-
V
G
-
I
N
-
P
V
V
V
H
G
G
G
P
Q
I
G
D
L
L
K
R
L
S
I
E
S
H
F
I
D
G
M
R
V
T
D
A
A
T
M
D
V
V
E
M
V
L
G
G
Q
V
N
K
D
I
V
N
L
I
N
R
H
G
G
S
A
I
G
L
T
G
K
D
A
E
L
I
R
A
K
K
L
-----
T
V
T
R
QTK
P
E
I
I
----
D
I
G
H
V
G
E
V
T
G
V
N
V
G
L
L
N
M
L
V
K
G
D
F
I
P
V
I
A
P
I
G
V
G
S
N
G
E
S
Y
N
I
N
A
D
L
V
A
G
K
V
A
E
A
L
K
A
E
K
L
M
L
L
T
N
I
A
G
L
MD--
K
Q
G
Q
----
V
L
T
G
-
L
S
T
E
Q
V
N
E
L
I
A
D
G
T
I
Y
G
G
M
L
P
K
I
R
C
A
L
E
A
V
Q
G
G
V
T
S
A
H
I
I
D
----------------------------------
28
PsiBlast_CBE
90.46
38%
-124
- C1 -
2BUF
2
ARGB_PSEAE
G:
[25-273]
V
G
K
T
L
V
I
K
Y
G
G
N
--
A
ME
S
--
E
E
---
L
K
--
A
G
F
A
R
D
V
V
L
M
K
A
-
V
G
-
I
N
-
P
V
V
V
H
G
G
G
P
Q
I
G
D
L
L
K
R
L
S
I
E
S
H
F
I
D
G
M
R
V
T
D
A
A
T
M
D
V
V
E
M
V
L
G
G
Q
V
N
K
D
I
V
N
L
I
N
R
H
G
G
S
A
I
G
L
T
G
K
D
A
E
L
I
R
A
K
K
L
-----
T
V
T
R
Q
T
PEMT
K
P
E
I
I
D
I
G
H
V
G
E
V
T
G
V
N
V
G
L
L
N
M
L
V
K
G
D
F
I
P
V
I
A
P
I
G
V
G
S
N
G
E
S
Y
N
I
N
A
D
L
V
A
G
K
V
A
E
A
L
K
A
E
K
L
M
L
L
T
N
I
A
G
L
M
D
--
K
Q
G
Q
----
V
L
T
G
-
L
S
T
E
Q
V
N
E
L
I
A
D
G
T
I
Y
G
G
M
L
P
K
I
R
C
A
L
E
A
V
Q
G
G
V
T
S
A
H
I
I
D
----------------------------------
2
PsiBlast_PDB
90.33
39%
-123
- C1 -
3L86
3
ARGB_STRMU
A:
[35-270]
M
K
D
I
I
V
I
K
I
G
G
V
--
A
--
S
--
Q
Q
---
L
S
--
G
D
F
L
S
Q
I
K
N
W
Q
D
-
A
G
-
K
Q
-
L
V
I
V
H
G
G
G
F
A
I
N
K
L
M
E
E
N
Q
V
P
V
K
K
I
N
G
L
R
V
T
S
K
D
D
M
V
L
V
S
H
A
L
L
D
L
V
G
K
N
L
Q
E
K
L
R
Q
A
G
V
S
C
Q
Q
L
K
S
D
I
K
H
V
V
A
A
D
Y
L
-----
D
K
D
------------
T
Y
G
Y
V
G
D
V
T
H
I
N
K
R
V
I
E
E
F
L
E
N
R
Q
I
P
I
L
A
S
L
G
Y
S
K
E
G
D
M
L
N
I
N
A
D
Y
L
A
T
A
V
A
V
A
L
A
A
D
K
L
I
L
M
T
N
V
K
G
V
----
L
E
N
G
----
A
V
L
E
K
I
T
S
H
Q
V
Q
E
K
I
D
T
A
V
I
T
A
G
M
I
P
K
I
E
S
A
A
K
T
V
A
A
G
V
G
Q
V
L
I
G
D
-
N
L
-------------------------------
3
PsiBlast_PDB
90.11
38%
-124
- C1 -
2BUF
-
ARGB_PSEAE
A:
[25-273]
V
G
K
T
L
V
I
K
Y
G
G
N
--
A
ME
S
--
E
E
---
L
K
--
A
G
F
A
R
D
V
V
L
M
K
A
-
V
G
-
I
N
-
P
V
V
V
H
G
G
G
P
Q
I
G
D
L
L
K
R
L
S
I
E
S
H
F
I
D
G
M
R
V
T
D
A
A
T
M
D
V
V
E
M
V
L
G
G
Q
V
N
K
D
I
V
N
L
I
N
R
H
G
G
S
A
I
G
L
T
G
K
D
A
E
L
I
R
A
K
K
L
-----
T
V
T
R
QII--------
D
I
G
H
V
G
E
V
T
G
V
N
V
G
L
L
N
M
L
V
K
G
D
F
I
P
V
I
A
P
I
G
V
G
S
N
G
E
S
Y
N
I
N
A
D
L
V
A
G
K
V
A
E
A
L
K
A
E
K
L
M
L
L
T
N
I
A
G
L
MD--
K
Q
G
Q
----
V
L
T
G
-
L
S
T
E
Q
V
N
E
L
I
A
D
G
T
I
Y
G
G
M
L
P
K
I
R
C
A
L
E
A
V
Q
G
G
V
T
S
A
H
I
I
D
----------------------------------
56
HHSearch
89.97
38%
-109
- C1 -
2BUF
-
ARGB_PSEAE
A:
[25-299]
V
G
K
T
L
V
I
K
Y
G
G
N
--
A
--
M
--
E
S
---
E
E
L
K
A
G
F
A
R
D
V
V
L
M
K
A
-
V
G
-
I
N
-
P
V
V
V
H
G
G
G
P
Q
I
G
D
L
L
K
R
L
S
I
E
S
H
F
I
D
G
M
R
V
T
D
A
A
T
M
D
V
V
E
M
V
L
G
G
Q
V
N
K
D
I
V
N
L
I
N
R
H
G
G
S
A
I
G
L
T
G
K
D
A
E
L
I
R
A
K
K
L
T
V
T
R
Q-
I
I
------------
D
I
G
H
V
G
E
V
T
G
V
N
V
G
L
L
N
M
L
V
K
G
D
F
I
P
V
I
A
P
I
G
V
G
S
N
G
E
S
Y
N
I
N
A
D
L
V
A
G
K
V
A
E
A
L
K
A
E
K
L
M
L
L
T
N
I
A
G
L
----
M
D
K
Q
G---
Q
V
L
T
G
L
S
T
E
Q
V
N
E
L
I
A
D
G
T
I
Y
G
G
M
L
P
K
I
R
C
A
L
E
A
V
Q
G
G
V
T
S
A
H
I
I
D
-
G
R
V
P
N
A
V
L
L
E
I
FTDSG
V
G
T
L
I
S
N
R
K
R
-------
1
PsiBlast_PDB
89.05
39%
-128
- C1 -
2BTY
3
ARGB_THEMA
A:
[23-254]
---
T
F
V
I
K
F
G
G
S
--
A
M
K
Q
--
E
N
---
A
K
--
K
A
F
I
Q
D
I
I
L
L
K
Y
-
T
G
-
I
K
-
P
I
I
V
H
G
G
G
P
A
I
S
Q
M
M
K
D
L
G
I
E
P
V
F
K
N
G
H
R
V
T
D
E
K
T
M
E
I
V
E
M
V
L
V
G
K
I
N
K
E
I
V
M
N
L
N
L
H
G
G
R
A
V
G
I
C
G
K
D
S
K
L
I
V
A
E
K
E
-----
T
K
H
G-----------
D
I
G
Y
V
G
K
V
K
K
V
N
P
E
I
L
H
A
L
I
E
N
D
Y
I
P
V
I
A
P
V
G
I
G
E
D
G
H
S
Y
N
I
N
A
D
T
A
A
A
E
I
A
K
S
L
M
A
E
K
L
I
L
L
T
D
V
D
G
V
----
L
K
D
G
----
K
L
I
S
T
L
T
P
D
E
A
E
E
L
I
R
D
G
T
V
T
G
G
M
I
P
K
V
E
C
A
V
S
A
V
R
G
G
V
G
A
V
H
I
------------------------------------
33
PsiBlast_CBE
88.38
38%
-115
- C1 -
2BUF
2
ARGB_PSEAE
B:
[25-273]
V
G
K
T
L
V
I
K
Y
G
G
N
--
A
ME
S
--
E
E
---
L
K
--
A
G
F
A
R
D
V
V
L
M
K
A
-
V
G
-
I
N
-
P
V
V
V
H
G
G
G
P
Q
I
G
D
L
L
K
R
L
S
I
E
S
H
F
I
D
G
M
R
V
T
D
A
A
T
M
D
V
V
E
M
V
L
G
G
Q
V
N
K
D
I
V
N
L
I
N
R
H
G
G
S
A
I
G
L
T
G
K
D
A
E
L
I
R
A
K
K
L
-----
T
V
T
RQEMT
K
P
E
I
I
--
D
I
G
H
V
G
E
V
T
G
V
N
V
G
L
L
N
M
L
V
K
G
D
F
I
P
V
I
A
P
I
G
V
G
S
N
G
E
S
Y
N
I
N
A
D
L
V
A
G
K
V
A
E
A
L
K
A
E
K
L
M
L
L
T
N
I
A
G
L
MD--
K
Q
G
Q
----
V
L
T
G
-
L
S
T
E
Q
V
N
E
L
I
A
D
G
T
I
Y
G
G
M
L
P
K
I
R
C
A
L
E
A
V
Q
G
G
V
T
S
A
H
I
I
D
----------------------------------
30
PsiBlast_CBE
87.80
38%
-123
- C1 -
2BUF
1
ARGB_PSEAE
E:
[25-273]
V
G
K
T
L
V
I
K
Y
G
G
N
--
A
ME
S
--
E
E
---
L
K
--
A
G
F
A
R
D
V
V
L
M
K
A
-
V
G
-
I
N
-
P
V
V
V
H
G
G
G
P
Q
I
G
D
L
L
K
R
L
S
I
E
S
H
F
I
D
G
M
R
V
T
D
A
A
T
M
D
V
V
E
M
V
L
G
G
Q
V
N
K
D
I
V
N
L
I
N
R
H
G
G
S
A
I
G
L
T
G
K
D
A
E
L
I
R
A
K
K
L
-----
T
V
T
II----------
D
I
G
H
V
G
E
V
T
G
V
N
V
G
L
L
N
M
L
V
K
G
D
F
I
P
V
I
A
P
I
G
V
G
S
N
G
E
S
Y
N
I
N
A
D
L
V
A
G
K
V
A
E
A
L
K
A
E
K
L
M
L
L
T
N
I
A
G
L
MD--
K
Q
G
Q
----
V
L
T
G
-
L
S
T
E
Q
V
N
E
L
I
A
D
G
T
I
Y
G
G
M
L
P
K
I
R
C
A
L
E
A
V
Q
G
G
V
T
S
A
H
I
I
D
----------------------------------
27
PsiBlast_CBE
87.52
38%
-124
- C1 -
2BUF
2
ARGB_PSEAE
H:
[25-273]
V
G
K
T
L
V
I
K
Y
G
G
N
--
A
ME
S
--
E
E
---
L
K
--
A
G
F
A
R
D
V
V
L
M
K
A
-
V
G
-
I
N
-
P
V
V
V
H
G
G
G
P
Q
I
G
D
L
L
K
R
L
S
I
E
S
H
F
I
D
G
M
R
V
T
D
A
A
T
M
D
V
V
E
M
V
L
G
G
Q
V
N
K
D
I
V
N
L
I
N
R
H
G
G
S
A
I
G
L
T
G
K
D
A
E
L
I
R
A
K
K
L
-----
T
V
T
R
Q
T
P
E
M
T
K
P
E
I
I
D
I
G
H
V
G
E
V
T
G
V
N
V
G
L
L
N
M
L
V
K
G
D
F
I
P
V
I
A
P
I
G
V
G
S
N
G
E
S
Y
N
I
N
A
D
L
V
A
G
K
V
A
E
A
L
K
A
E
K
L
M
L
L
T
N
I
A
G
L
MD--
K
Q
G
Q
----
V
L
T
G
-
L
S
T
E
Q
V
N
E
L
I
A
D
G
T
I
Y
G
G
M
L
P
K
I
R
C
A
L
E
A
V
Q
G
G
V
T
S
A
H
I
I
D
----------------------------------
26
PsiBlast_CBE
87.12
38%
-116
- C1 -
2BUF
1
ARGB_PSEAE
I:
[25-273]
V
G
K
T
L
V
I
K
Y
G
G
N
--
A
ME
S
--
E
E
---
L
K
--
A
G
F
A
R
D
V
V
L
M
K
A
-
V
G
-
I
N
-
P
V
V
V
H
G
G
G
P
Q
I
G
D
L
L
K
R
L
S
I
E
S
H
F
I
D
G
M
R
V
T
D
A
A
T
M
D
V
V
E
M
V
L
G
G
Q
V
N
K
D
I
V
N
L
I
N
R
H
G
G
S
A
I
G
L
T
G
K
D
A
E
L
I
R
A
K
K
L
-----
T
V
T
REI
I
--------
D
I
G
H
V
G
E
V
T
G
V
N
V
G
L
L
N
M
L
V
K
G
D
F
I
P
V
I
A
P
I
G
V
G
S
N
G
E
S
Y
N
I
N
A
D
L
V
A
G
K
V
A
E
A
L
K
A
E
K
L
M
L
L
T
N
I
A
G
L
MD--
K
Q
G
Q
----
V
L
T
G
-
L
S
T
E
Q
V
N
E
L
I
A
D
G
T
I
Y
G
G
M
L
P
K
I
R
C
A
L
E
A
V
Q
G
G
V
T
S
A
H
I
I
D
----------------------------------
40
PsiBlast_CBE
85.97
34%
-125
- C1 -
4USJ
2
NAGK_ARATH
B:
[58-295]
---
T
I
V
V
K
Y
G
G
A
--
A
MT
S
--
P
E
---
L
K
--
S
S
V
V
S
D
L
V
L
L
A
C
-
V
G
-
L
R
-
P
I
L
V
H
G
G
G
P
D
I
N
R
Y
L
K
Q
L
N
I
P
A
E
F
R
D
G
L
R
V
T
D
A
T
T
M
E
I
V
S
M
V
L
V
G
K
V
N
K
N
L
V
S
L
I
N
A
A
G
A
T
A
V
G
L
S
G
H
D
G
R
L
L
T
A
R
P
V
-----
P
N
S
A-----------
Q
L
G
F
V
G
E
V
A
R
V
D
P
S
V
L
R
P
L
V
D
Y
G
Y
I
P
V
I
A
S
V
A
A
D
D
S
G
Q
A
Y
N
I
N
A
D
T
V
A
G
E
L
A
A
A
L
G
A
E
K
L
I
L
L
T
D
V
A
G
I
LENK
E
D
P
S
----
S
L
I
K
E
I
D
I
K
G
V
K
K
M
I
E
D
G
K
V
A
G
G
M
I
P
K
V
K
C
C
I
R
S
L
A
Q
G
V
K
T
A
S
I
I
D
----------------------------------
22
PsiBlast_CBE
85.48
39%
-126
- C1 -
2BTY
2
ARGB_THEMA
B:
[23-254]
---
T
F
V
I
K
F
G
G
S
--
A
MK
Q
--
E
N
---
A
K
--
K
A
F
I
Q
D
I
I
L
L
K
Y
-
T
G
-
I
K
-
P
I
I
V
H
G
G
G
P
A
I
S
Q
M
M
K
D
L
G
I
E
P
V
F
K
N
G
H
R
V
T
D
E
K
T
M
E
I
V
E
M
V
L
V
G
K
I
N
K
E
I
V
M
N
L
N
L
H
G
G
R
A
V
G
I
C
G
K
D
S
K
L
I
V
A
E
K
E
-----
T
K
H
G-----------
D
I
G
Y
V
G
K
V
K
K
V
N
P
E
I
L
H
A
L
I
E
N
D
Y
I
P
V
I
A
P
V
G
I
G
E
D
G
H
S
Y
N
I
N
A
D
T
A
A
A
E
I
A
K
S
L
M
A
E
K
L
I
L
L
T
D
V
D
G
V
----
L
K
D
G
----
K
L
I
S
T
L
T
P
D
E
A
E
E
L
I
R
D
G
T
V
T
G
G
M
I
P
K
V
E
C
A
V
S
A
V
R
G
G
V
G
A
V
H
I
------------------------------------
7
PsiBlast_PDB
85.14
34%
-126
- C1 -
2RD5
3
NAGK_ARATH
A:
[38-275]
---
T
I
V
V
K
Y
G
G
A
--
A
M
T
S
--
P
E
---
L
K
--
S
S
V
V
S
D
L
V
L
L
A
C
-
V
G
-
L
R
-
P
I
L
V
H
G
G
G
P
D
I
N
R
Y
L
K
Q
L
N
I
P
A
E
F
R
D
G
L
R
V
T
D
A
T
T
M
E
I
V
S
M
V
L
V
G
K
V
N
K
N
L
V
S
L
I
N
A
A
G
A
T
A
V
G
L
S
G
H
D
G
R
L
L
T
A
R
P
V
-----
P
N
S
A-----------
Q
L
G
F
V
G
E
V
A
R
V
D
P
S
V
L
R
P
L
V
D
Y
G
Y
I
P
V
I
A
S
V
A
A
D
D
S
G
Q
A
Y
N
I
N
A
D
T
V
A
G
E
L
A
A
A
L
G
A
E
K
L
I
L
L
T
D
V
A
G
I
LENK
E
D
P
S
----
S
L
I
K
E
I
D
I
K
G
V
K
K
M
I
E
D
G
K
V
A
G
G
M
I
P
K
V
K
C
C
I
R
S
L
A
Q
G
V
K
T
A
S
I
I
D
----------------------------------
21
PsiBlast_CBE
84.89
39%
-131
- C1 -
2BTY
2
ARGB_THEMA
C:
[23-254]
---
T
F
V
I
K
F
G
G
S
--
A
MK
Q
--
E
N
---
A
K
--
K
A
F
I
Q
D
I
I
L
L
K
Y
-
T
G
-
I
K
-
P
I
I
V
H
G
G
G
P
A
I
S
Q
M
M
K
D
L
G
I
E
P
V
F
K
N
G
H
R
V
T
D
E
K
T
M
E
I
V
E
M
V
L
V
G
K
I
N
K
E
I
V
M
N
L
N
L
H
G
G
R
A
V
G
I
C
G
K
D
S
K
L
I
V
A
E
K
E
-----
T
K
H
G-----------
D
I
G
Y
V
G
K
V
K
K
V
N
P
E
I
L
H
A
L
I
E
N
D
Y
I
P
V
I
A
P
V
G
I
G
E
D
G
H
S
Y
N
I
N
A
D
T
A
A
A
E
I
A
K
S
L
M
A
E
K
L
I
L
L
T
D
V
D
G
V
----
L
K
D
G
----
K
L
I
S
T
L
T
P
D
E
A
E
E
L
I
R
D
G
T
V
T
G
G
M
I
P
K
V
E
C
A
V
S
A
V
R
G
G
V
G
A
V
H
I
------------------------------------
59
HHSearch
83.53
34%
-114
- C1 -
2RD5
3
NAGK_ARATH
A:
[35-279]
R
G
K
T
I
V
V
K
Y
G
G
A
--
A
--
M
--
T
S
---
P
E
L
K
S
S
V
V
S
D
L
V
L
L
A
C
-
V
G
-
L
R
-
P
I
L
V
H
G
G
G
P
D
I
N
R
Y
L
K
Q
L
N
I
P
A
E
F
R
D
G
L
R
V
T
D
A
T
T
M
E
I
V
S
M
V
L
V
G
K
V
N
K
N
L
V
S
L
I
N
A
A
G
A
T
A
V
G
L
S
G
H
D
G
R
L
L
T
A
R
P
V
P----
N
S
A
------------
Q
L
G
F
V
G
E
V
A
R
V
D
P
S
V
L
R
P
L
V
D
Y
G
Y
I
P
V
I
A
S
V
A
A
D
D
S
G
Q
A
Y
N
I
N
A
D
T
V
A
G
E
L
A
A
A
L
G
A
E
K
L
I
L
L
T
D
V
A
G
I
----
L
E
N
K
EDPS
S
L
I
K
E
I
D
I
K
G
V
K
K
M
I
E
D
G
K
V
A
G
G
M
I
P
K
V
K
C
C
I
R
S
L
A
Q
G
V
K
T
A
S
I
I
D
-
G
R
R
Q
-----------------------------
5
PsiBlast_PDB
83.47
33%
-117
- C1 -
2V5H
1
ARGB_SYNE7
A:
[50-287]
--
R
T
V
V
V
K
Y
G
G
A
--
A
MK
Q
--
E
E
---
L
K
--
E
A
V
M
R
D
I
V
F
L
A
C
-
V
G
-
M
R
-
P
V
V
V
H
G
G
G
P
E
I
N
A
W
L
G
R
V
G
I
E
P
Q
F
H
N
G
L
R
V
T
D
A
D
T
M
E
V
V
E
M
V
L
V
G
R
V
N
K
D
I
V
S
R
I
N
T
T
G
G
R
A
V
G
F
C
G
T
D
G
R
L
V
L
A
R
P
H
-----
D
Q
E
------------
G
I
G
F
V
G
E
V
N
S
V
N
S
E
V
I
E
P
L
L
E
R
G
Y
I
P
V
I
S
S
V
A
A
D
E
N
G
Q
S
F
N
I
N
A
D
T
V
A
G
E
I
A
A
A
L
N
A
E
K
L
I
L
L
T
D
T
R
G
I
LEDP
K
R
P
E
----
S
L
I
P
R
L
N
I
P
Q
S
R
E
L
I
A
Q
G
I
V
G
G
G
M
I
P
K
V
D
C
C
I
R
S
L
A
Q
G
V
R
A
A
H
I
I
D
----------------------------------
41
PsiBlast_CBE
82.63
34%
-119
- C1 -
2RD5
4
NAGK_ARATH
B:
[38-275]
---
T
I
V
V
K
Y
G
G
A
--
A
MT
S
--
P
E
---
L
K
--
S
S
V
V
S
D
L
V
L
L
A
C
-
V
G
-
L
R
-
P
I
L
V
H
G
G
G
P
D
I
N
R
Y
L
K
Q
L
N
I
P
A
E
F
R
D
G
L
R
V
T
D
A
T
T
M
E
I
V
S
M
V
L
V
G
K
V
N
K
N
L
V
S
L
I
N
A
A
G
A
T
A
V
G
L
S
G
H
D
G
R
L
L
T
A
R
P
V
-----
P
N
S
A-----------
Q
L
G
F
V
G
E
V
A
R
V
D
P
S
V
L
R
P
L
V
D
Y
G
Y
I
P
V
I
A
S
V
A
A
D
D
S
G
Q
A
Y
N
I
N
A
D
T
V
A
G
E
L
A
A
A
L
G
A
E
K
L
I
L
L
T
D
V
A
G
I
LENK
E
D
P
S
----
S
L
I
K
E
I
D
I
K
G
V
K
K
M
I
E
D
G
K
V
A
G
G
M
I
P
K
V
K
C
C
I
R
S
L
A
Q
G
V
K
T
A
S
I
I
D
----------------------------------
6
PsiBlast_PDB
81.86
34%
-119
- C1 -
4USJ
3
NAGK_ARATH
A:
[58-295]
---
T
I
V
V
K
Y
G
G
A
--
A
MT
S
--
P
E
---
L
K
--
S
S
V
V
S
D
L
V
L
L
A
C
-
V
G
-
L
R
-
P
I
L
V
H
G
G
G
P
D
I
N
R
Y
L
K
Q
L
N
I
P
A
E
F
R
D
G
L
R
V
T
D
A
T
T
M
E
I
V
S
M
V
L
V
G
K
V
N
K
N
L
V
S
L
I
N
A
A
G
A
T
A
V
G
L
S
G
H
D
G
R
L
L
T
A
R
P
V
-----
P
N
S
A-----------
Q
L
G
F
V
G
E
V
A
R
V
D
P
S
V
L
R
P
L
V
D
Y
G
Y
I
P
V
I
A
S
V
A
A
D
D
S
G
Q
A
Y
N
I
N
A
D
T
V
A
G
E
L
A
A
A
L
G
A
E
K
L
I
L
L
T
D
V
A
G
I
LENK
E
D
P
S
----
S
L
I
K
E
I
D
I
K
G
V
K
K
M
I
E
D
G
K
V
A
G
G
M
I
P
K
V
K
C
C
I
R
S
L
A
Q
G
V
K
T
A
S
I
I
D
----------------------------------
39
PsiBlast_CBE
80.24
33%
-119
- C1 -
2JJ4
1
ARGB_SYNE7
B:
[50-287]
--
R
T
V
V
V
K
Y
G
G
A
--
A
MK
Q
--
E
E
---
L
K
--
E
A
V
M
R
D
I
V
F
L
A
C
-
V
G
-
M
R
-
P
V
V
V
H
G
G
G
P
E
I
N
A
W
L
G
R
V
G
I
E
P
Q
F
H
N
G
L
R
V
T
D
A
D
T
M
E
V
V
E
M
V
L
V
G
R
V
N
K
D
I
V
S
R
I
N
T
T
G
G
R
A
V
G
F
C
G
T
D
G
R
L
V
L
A
R
P
H
-----
D
Q
E
------------
G
I
G
F
V
G
E
V
N
S
V
N
S
E
V
I
E
P
L
L
E
R
G
Y
I
P
V
I
S
S
V
A
A
D
E
N
G
Q
S
F
N
I
N
A
D
T
V
A
G
E
I
A
A
A
L
N
A
E
K
L
I
L
L
T
D
T
R
G
I
LEDP
K
R
P
E
----
S
L
I
P
R
L
N
I
P
Q
S
R
E
L
I
A
Q
G
I
V
G
G
G
M
I
P
K
V
D
C
C
I
R
S
L
A
Q
G
V
R
A
A
H
I
I
D
----------------------------------
4
PsiBlast_PDB
79.84
33%
-118
- C1 -
2JJ4
1
ARGB_SYNE7
A:
[50-287]
--
R
T
V
V
V
K
Y
G
G
A
--
A
MK
Q
--
E
E
---
L
K
--
E
A
V
M
R
D
I
V
F
L
A
C
-
V
G
-
M
R
-
P
V
V
V
H
G
G
G
P
E
I
N
A
W
L
G
R
V
G
I
E
P
Q
F
H
N
G
L
R
V
T
D
A
D
T
M
E
V
V
E
M
V
L
V
G
R
V
N
K
D
I
V
S
R
I
N
T
T
G
G
R
A
V
G
F
C
G
T
D
G
R
L
V
L
A
R
P
H
-----
D
Q
E
------------
G
I
G
F
V
G
E
V
N
S
V
N
S
E
V
I
E
P
L
L
E
R
G
Y
I
P
V
I
S
S
V
A
A
D
E
N
G
Q
S
F
N
I
N
A
D
T
V
A
G
E
I
A
A
A
L
N
A
E
K
L
I
L
L
T
D
T
R
G
I
LEDP
K
R
P
E
----
S
L
I
P
R
L
N
I
P
Q
S
R
E
L
I
A
Q
G
I
V
G
G
G
M
I
P
K
V
D
C
C
I
R
S
L
A
Q
G
V
R
A
A
H
I
I
D
----------------------------------
12
PsiBlast_PDB
78.21
34%
-127
- C1 -
2WXB
3
ARGB_ECOLI
A:
[3-226]
--
N
P
L
I
I
K
L
G
G
V
--
L
L
D
S
--
E
E
---
A
L
--
E
R
L
F
S
A
L
V
N
Y
R
E
-
S
H
-
Q
R
P
L
V
I
V
H
G
G
G
C
V
V
D
E
L
M
K
G
L
N
L
P
V
K
K
K
N
G
L
R
V
T
P
A
D
Q
I
D
I
I
T
G
A
L
A
G
T
A
N
K
T
L
L
A
W
A
K
K
H
Q
I
A
A
V
G
L
F
L
G
D
G
D
S
V
K
V
T
Q
L
------
D
E
------------
E
L
G
H
V
G
L
A
Q
P
G
S
P
K
L
I
N
S
L
L
E
N
G
Y
L
P
V
V
S
S
I
G
V
T
D
E
G
Q
L
M
N
V
N
A
D
Q
A
A
T
A
L
A
A
T
L
G
A
D
-
L
I
L
L
S
D
V
S
G
I
----
L
D
G
K
G---
Q
R
I
A
E
M
T
A
A
K
A
E
Q
L
I
E
Q
G
I
I
T
D
G
M
I
V
K
V
N
A
A
L
D
A
A
R
--------------------------------------------
13
PsiBlast_PDB
78.10
34%
-127
- C1 -
2X2W
2
ARGB_ECOLI
A:
[3-226]
--
N
P
L
I
I
K
L
G
G
V
--
L
L
D
S
--
E
E
---
A
L
--
E
R
L
F
S
A
L
V
N
Y
R
E
-
S
H
-
Q
R
P
L
V
I
V
H
G
G
G
C
V
V
D
E
L
M
K
G
L
N
L
P
V
K
K
K
N
G
L
R
V
T
P
A
D
Q
I
D
I
I
T
G
A
L
A
G
T
A
N
K
T
L
L
A
W
A
K
K
H
Q
I
A
A
V
G
L
F
L
G
D
G
D
S
V
K
V
T
Q
L
------
D
E
------------
E
L
G
H
V
G
L
A
Q
P
G
S
P
K
L
I
N
S
L
L
E
N
G
Y
L
P
V
V
S
S
I
G
V
T
D
E
G
Q
L
M
N
V
N
A
D
Q
A
A
T
A
L
A
A
T
L
G
A
D
-
L
I
L
L
S
D
V
S
G
I
----
L
D
G
K
G---
Q
R
I
A
E
M
T
A
A
K
A
E
Q
L
I
E
Q
G
I
I
T
D
G
M
I
V
K
V
N
A
A
L
D
A
A
R
--------------------------------------------
43
PsiBlast_CBE
76.85
34%
-123
- C1 -
2WXB
2
ARGB_ECOLI
B:
[3-226]
--
N
P
L
I
I
K
L
G
G
V
--
L
LD
S
--
E
E
---
A
L
--
E
R
L
F
S
A
L
V
N
Y
R
E
-
S
H
-
Q
R
P
L
V
I
V
H
G
G
G
C
V
V
D
E
L
M
K
G
L
N
L
P
V
K
K
K
N
G
L
R
V
T
P
A
D
Q
I
D
I
I
T
G
A
L
A
G
T
A
N
K
T
L
L
A
W
A
K
K
H
Q
I
A
A
V
G
L
F
L
G
D
G
D
S
V
K
V
T
Q
L
------
D
E
------------
E
L
G
H
V
G
L
A
Q
P
G
S
P
K
L
I
N
S
L
L
E
N
G
Y
L
P
V
V
S
S
I
G
V
T
D
E
G
Q
L
M
N
V
N
A
D
Q
A
A
T
A
L
A
A
T
L
G
A
D
-
L
I
L
L
S
D
V
S
G
I
----
L
D
G
K
G---
Q
R
I
A
E
M
T
A
A
K
A
E
Q
L
I
E
Q
G
I
I
T
D
G
M
I
V
K
V
N
A
A
L
D
A
A
R
--------------------------------------------
15
PsiBlast_PDB
75.51
33%
-109
- C1 -
3T7B
1
ARGB_YERPE
A:
[5-242]
--
N
P
L
V
I
K
L
G
G
V
--
L
--
L
--
D
S
E
E
A
L
E
--
R
L
F
T
A
L
V
T
Y
R
E
K
-
H
E
-
R
P
-
L
V
I
M
H
G
G
G
C
L
V
D
E
L
M
K
R
L
A
L
P
V
V
K
K
N
G
L
R
V
T
P
A
D
Q
I
D
I
I
T
G
A
L
A
G
T
A
N
K
T
L
L
A
W
A
V
K
H
Q
I
N
A
V
G
L
C
L
A
D
G
N
T
V
T
V
T
L
L
------
D
A
------------
E
L
G
H
V
G
K
A
Q
P
G
S
A
A
L
V
Q
T
L
L
A
A
G
Y
M
P
I
I
S
S
I
G
I
T
V
E
G
Q
L
M
N
V
N
A
D
Q
A
A
T
A
L
A
A
T
L
G
A
D
-
L
I
L
L
S
D
V
S
G
I
----
L
D
------
Q
R
I
A
E
M
T
A
Q
K
A
E
Q
L
I
A
Q
G
I
I
T
D
G
M
V
V
K
V
-
N
A
A
L
D
A
A
R
S
L
G
R
P
V
D
I
A
-
S
W
R
H
------------
S
----------------
9
PsiBlast_PDB
74.43
34%
-114
- C1 -
1OH9
4
ARGB_ECOLI
A:
[3-226]
--
N
P
L
I
I
K
L
G
G
V
--
L
LD
S
--
E
E
---
A
L
--
E
R
L
F
S
A
L
V
N
Y
R
E
-
S
H
-
Q
R
P
L
V
I
V
H
G
G
G
C
V
V
D
E
L
M
K
G
L
N
L
P
V
K
K
K
N
G
L
R
V
T
P
A
D
Q
I
D
I
I
T
G
A
L
A
G
T
A
N
K
T
L
L
A
W
A
K
K
H
Q
I
A
A
V
G
L
F
L
G
D
G
D
S
V
K
V
T
Q
L
------
D
E
------------
E
L
G
H
V
G
L
A
Q
P
G
S
P
K
L
I
N
S
L
L
E
N
G
Y
L
P
V
V
S
S
I
G
V
T
D
E
G
Q
L
M
N
V
N
A
D
Q
A
A
T
A
L
A
A
T
L
G
A
D
-
L
I
L
L
S
D
V
S
G
I
----
L
D
G
K
G---
Q
R
I
A
E
M
T
A
A
K
A
E
Q
L
I
E
Q
G
I
I
T
D
G
M
I
V
K
V
N
A
A
L
D
A
A
R
--------------------------------------------
10
PsiBlast_PDB
73.29
34%
-113
- C1 -
1OHA
3
ARGB_ECOLI
A:
[3-226]
--
N
P
L
I
I
K
L
G
G
V
--
L
LD
S
--
E
E
---
A
L
--
E
R
L
F
S
A
L
V
N
Y
R
E
-
S
H
-
Q
R
P
L
V
I
V
H
G
G
G
C
V
V
D
E
L
M
K
G
L
N
L
P
V
K
K
K
N
G
L
R
V
T
P
A
D
Q
I
D
I
I
T
G
A
L
A
G
T
A
N
K
T
L
L
A
W
A
K
K
H
Q
I
A
A
V
G
L
F
L
G
D
G
D
S
V
K
V
T
Q
L
------
D
E
------------
E
L
G
H
V
G
L
A
Q
P
G
S
P
K
L
I
N
S
L
L
E
N
G
Y
L
P
V
V
S
S
I
G
V
T
D
E
G
Q
L
M
N
V
N
A
D
Q
A
A
T
A
L
A
A
T
L
G
A
D
-
L
I
L
L
S
D
V
S
G
I
----
L
D
G
K
G---
Q
R
I
A
E
M
T
A
A
K
A
E
Q
L
I
E
Q
G
I
I
T
D
G
M
I
V
K
V
N
A
A
L
D
A
A
R
--------------------------------------------
11
PsiBlast_PDB
73.13
34%
-112
- C1 -
1OHB
3
ARGB_ECOLI
A:
[3-226]
--
N
P
L
I
I
K
L
G
G
V
--
L
LD
S
--
E
E
---
A
L
--
E
R
L
F
S
A
L
V
N
Y
R
E
-
S
H
-
Q
R
P
L
V
I
V
H
G
G
G
C
V
V
D
E
L
M
K
G
L
N
L
P
V
K
K
K
N
G
L
R
V
T
P
A
D
Q
I
D
I
I
T
G
A
L
A
G
T
A
N
K
T
L
L
A
W
A
K
K
H
Q
I
A
A
V
G
L
F
L
G
D
G
D
S
V
K
V
T
Q
L
------
D
E
------------
E
L
G
H
V
G
L
A
Q
P
G
S
P
K
L
I
N
S
L
L
E
N
G
Y
L
P
V
V
S
S
I
G
V
T
D
E
G
Q
L
M
N
V
N
A
D
Q
A
A
T
A
L
A
A
T
L
G
A
D
-
L
I
L
L
S
D
V
S
G
I
----
L
D
G
K
G---
Q
R
I
A
E
M
T
A
A
K
A
E
Q
L
I
E
Q
G
I
I
T
D
G
M
I
V
K
V
N
A
A
L
D
A
A
R
--------------------------------------------
14
PsiBlast_PDB
73.04
33%
-111
- C1 -
1GSJ
3
ARGB_ECOLI
A:
[3-226]
--
N
P
L
I
I
K
L
G
G
V
LL
D
--
S
--
E
E
---
A
L
--
E
R
L
F
S
A
L
V
N
Y
R
E
-
S
H
-
Q
R
P
L
V
I
V
H
G
G
G
C
V
V
D
E
L
M
K
G
L
N
L
P
V
K
K
K
N
G
L
R
V
T
P
A
D
Q
I
D
I
I
T
G
A
L
A
G
T
A
N
K
T
L
L
A
W
A
K
K
H
Q
I
A
A
V
G
L
F
L
G
D
G
D
S
V
K
V
T
Q
L
------
D
E
------------
E
L
G
H
V
G
L
A
Q
P
G
S
P
K
L
I
N
S
L
L
E
N
G
Y
L
P
V
V
S
S
I
G
V
T
D
E
G
Q
L
M
N
V
N
A
D
Q
A
A
T
A
L
A
A
T
L
G
A
D
-
L
I
L
L
S
D
V
S
G
I
----
L
D
G
K
G---
Q
R
I
A
E
M
T
A
A
K
A
E
Q
L
I
E
Q
G
I
I
T
D
G
M
I
V
K
V
N
A
A
L
D
A
A
R
--------------------------------------------
42
PsiBlast_CBE
72.62
34%
-119
- C1 -
2X2W
2
ARGB_ECOLI
B:
[3-226]
--
N
P
L
I
I
K
L
G
G
V
--
L
LD
S
--
E
E
---
A
L
--
E
R
L
F
S
A
L
V
N
Y
R
E
-
S
H
-
Q
R
P
L
V
I
V
H
G
G
G
C
V
V
D
E
L
M
K
G
L
N
L
P
V
K
K
K
N
G
L
R
V
T
P
A
D
Q
I
D
I
I
T
G
A
L
A
G
T
A
N
K
T
L
L
A
W
A
K
K
H
Q
I
A
A
V
G
L
F
L
G
D
G
D
S
V
K
V
T
Q
L
------
D
E
------------
E
L
G
H
V
G
L
A
Q
P
G
S
P
K
L
I
N
S
L
L
E
N
G
Y
L
P
V
V
S
S
I
G
V
T
D
E
G
Q
L
M
N
V
N
A
D
Q
A
A
T
A
L
A
A
T
L
G
A
D
-
L
I
L
L
S
D
V
S
G
I
----
L
D
G
K
G---
Q
R
I
A
E
M
T
A
A
K
A
E
Q
L
I
E
Q
G
I
I
T
D
G
M
I
V
K
V
N
A
A
L
D
A
A
R
--------------------------------------------
8
PsiBlast_PDB
69.50
34%
-111
- C1 -
1GS5
3
ARGB_ECOLI
A:
[3-226]
--
N
P
L
I
I
K
L
G
G
V
--
L
LD
S
--
E
E
---
A
L
--
E
R
L
F
S
A
L
V
N
Y
R
E
-
S
H
-
Q
R
P
L
V
I
V
H
G
G
G
C
V
V
D
E
L
M
K
G
L
N
L
P
V
K
K
K
N
G
L
R
V
T
P
A
D
Q
I
D
I
I
T
G
A
L
A
G
T
A
N
K
T
L
L
A
W
A
K
K
H
Q
I
A
A
V
G
L
F
L
G
D
G
D
S
V
K
V
T
Q
L
------
D
E
------------
E
L
G
H
V
G
L
A
Q
P
G
S
P
K
L
I
N
S
L
L
E
N
G
Y
L
P
V
V
S
S
I
G
V
T
D
E
G
Q
L
M
N
V
N
A
D
Q
A
A
T
A
L
A
A
T
L
G
A
D
-
L
I
L
L
S
D
V
S
G
I
----
L
D
G
K
G---
Q
R
I
A
E
M
T
A
A
K
A
E
Q
L
I
E
Q
G
I
I
T
D
G
M
I
V
K
V
N
A
A
L
D
A
A
R
--------------------------------------------
62
HHSearch
68.71
34%
-100
- C1 -
1GS5
3
ARGB_ECOLI
A:
[2-258]
-
M
N
P
L
I
I
K
L
G
G
V
--
L
--
L
--
D
S
---
E
E
A
L
E
R
L
F
S
A
L
V
N
Y
R
E
S
H
Q
-
R
P
-
L
V
I
V
H
G
G
G
C
V
V
D
E
L
M
K
G
L
N
L
P
V
K
K
K
N
G
L
R
V
T
P
A
D
Q
I
D
I
I
T
G
A
L
A
G
T
A
N
K
T
L
L
A
W
A
K
K
H
Q
I
A
A
V
G
L
F
L
G
D
G
D
S
V
K
V
T
Q
L
-----
D
-
E
------------
E
L
G
H
V
G
L
A
Q
P
G
S
P
K
L
I
N
S
L
L
E
N
G
Y
L
P
V
V
S
S
I
G
V
T
D
E
G
Q
L
M
N
V
N
A
D
Q
A
A
T
A
L
A
A
T
L
G
A
D
-
L
I
L
L
S
D
V
S
G
I
----
L
D
G
K
G---
Q
R
I
A
E
M
T
A
A
K
A
E
Q
L
I
E
Q
G
I
I
T
D
G
M
I
V
K
V
N
A
A
L
D
A
A
R
T
L
G
R
P
V
D
I
A
S
-
W
R
H
A
EQ
L
P
A
L
F
N
GMP-
M
G
T
R
I
L
A
----------
78
Fugue
66.21
32%
-98
- C1 -
1GS5
3
ARGB_ECOLI
A:
[1-258]
M
M
N
P
L
I
I
K
L
G
G
V
--
L
--
L
DS
E
E
---
A
L
--
E
R
L
F
S
A
L
V
N
Y
R
E
-
S
H
Q
R
P
-
L
V
I
V
H
G
G
G
C
V
V
D
E
L
M
K
G
L
N
L
P
V
K
K
K
N
G
L
R
V
T
P
A
D
Q
I
D
I
I
T
G
A
L
A
G
T
A
N
K
T
L
L
A
W
A
K
K
H
Q
I
A
A
V
G
L
F
L
G
D
G
D
S
V
K
V
T
Q
------
L
D
E
------------
E
L
G
H
V
G
L
A
Q
P
G
S
P
K
L
I
N
S
L
L
E
N
G
Y
L
P
V
V
S
S
I
G
V
T
D
E
G
Q
L
M
N
V
N
A
D
Q
A
A
T
A
L
A
A
T
L
G
A
-
D
L
I
L
L
S
D
V
S
G
I
----
L
D
G
K
G---
Q
R
I
A
E
M
T
A
A
K
A
E
Q
L
I
E
Q
G
I
I
T
D
G
M
I
V
K
V
N
A
A
L
D
A
A
R
T
L
G
R
P
V
D
I
A
S
W
R
H
A
E
------------
Q
L
P
A
L
F
N
G
M
P
M
G
T
R
I
L
A