@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1666: (2016-03-27 )
MKSKFFIGMMTFLLSLICLTGMKAEAKSVGDISPDDISPEISDNRFQSAEGKVLPNFEVDMSISDQNNGKLSIDEDFELTSDGDIILIGTVQGQYIQGTPILNENGQLNKIPNRDQGIIMRVDRTTKKVEWARVVNYEDGNYNSQYAADKWFSSYKSITTNSSKSTFYVGGEVVNYYGDSGGGSTLIVKSIDANGNFQIAHKSYVSYGVPSRSDLTYAYFMDIQMEGNTLTMSASARYAAQGKQFIRYTLEPASLSITKNEFNPLDNTFWAKYQRTDVLKVDNKGLMAYNADVNGANQLKMSIRESENNYKEITLFDSVPEILANSSPYIFMEDRGDGNVFVVMSTPTTWYIALVNIASEQVVETKKMTMNSSTTLNSVIYSEGKGLLLGGSTHAEESIFGSEPLNKNNGYYLALGNDLNVTDSQILRTNQHNSLTTIINGVGNKVDGFFSYDGLNNDGYIQNVEYPNTYDVNPNGAMIFAEFNLQPAPVLDTGNPILAFYQGERRADFDELEGVKAYSGIDSSDVTKSITKNTFDLYTVGVQQQLYQIEYLPGSGNKTTGTRNVQLIHPLETPKLEKSYADSHGAFKVGEVVPANAIHAFNGLDSANNVTYVVTAVDDEKITVDASIKRTEGTKTAVINKEITLMTSTADETAVIDVTSVALAAGKYTSLTDVRNEGHFHIYAETMDSVSIDPKYVKLTEDPENPVDWNAPGVYYVTASLDPASGYTAKDVKVSVAVVDVGSPKVISVNMKPYNPTTALVVAEDDINGAGVYKINWAIKDANGLIIQQGVEESGATIRVQTPVPIDLSTLNDGNYTLSVSAADRIGHTSEASEKAFTVDRQAPVVTADDKITYEINTKKTEEEFLNDVNVKTEAGAVIKTNFDTMVRMDSPGDYTVLVEATDAAGNQSDPIYVIVTVEDTVAPIISADEAISYNQGNIRTEALFLTDIHATTDEPATITSDFADQVKFDTPGVYAVTLKANDISGNQAIPRTVNVTIKDVTAPVITADEAIIYEKGITKSATDFLTDIHATTNDGSAITSNFATVVDLNTPGDYDVTLSSTDTGGNISDPVTITVTVRDTTPPVITADTTITYEKGTTKTAAAFLTDVNATTNDGSAVTSNFNPISLKQVGTYQVTLSSVDENGNYALPVKVTVVVQDTQKPVISSSATSITYERGEKKQETGFFLDLAIKTDDGTPVTSDFDTAVNLDTAGTYTVTLNSEDESGNKADPVTITVTVADTEKPIITADTTITYAKGTTKTVAQFLTDIHATTNDGSTIISNFDPTVLAQEGTYTVVLNAKDESNNEADPVTVTITVVDTKGPIINALNAITYERTINKNEADFLADIEATTDDGSTITTDFNSKDLDTVGTYIVTLNAEDASGNKATPVKVTIKVEDTIPPIITADQSITYERGITKTEQAFYTDIKAATSDNSPISSDFSKIDLTKTGNYEVLLRATDQSGNKALPLKINVLVQDTIAPVIKTTSREITAERGTPMTEQQLLAKIGANTDDGSKITTDYNPAIVNTSGDYLVHLYAVDAAGNQAIPVEITIHVKDTTAPIIKADKKISYPVGTVKTVTEFLQDIHATTDDGSKITTDFDPNMLKTPGKYTIHLNAVDADGNKAKTIDVSLTVEEKVTPPKPPTPDDGGNNTNGSNGTNGSNTDITVNPTKQNTTATNESIPALGDTKSTIPVIVGMFLLATSLVLIRRK
Atome Classification :
(20 SA)
.........10........20........30........40........50........60........70........80........90........100.......110.......120.......130.......140.......150.......160.......170.......180.......190.......200.......210.......220.......230.......240.......250.......260.......270.......280.......290.......300.......310.......320.......330.......340.......350.......360.......370.......380.......390.......400.......410.......420.......430.......440.......450.......460.......470.......480.......490.......500.......510.......520.......530.......540.......550.......560.......570.......580.......590.......600.......610.......620.......630.......640.-......650.......660.......670.......680.......690.......700.......710.......720.......730.......740-........750.......760.......770.......780.......790......--.800.......810.......820.......830.......840....---...850.......860.......870--.......-880.......890.......900......------------.910.-.-------.....920.........930.......940.......950.......960.......-------------------------------970.......980.......990--..-.......1000.--.....1010......1020.....----.1030......1040...-...1050......1060......1070......-1080.......-1090.----.....1100......1110......1120-...-------.--...1130.......1140......-----1150.------.....1160......1170......1180....-----....------.1190.-.....1200------.......1210......1220.....-.1230..---.....1240....--..----.-------------1250....--...1260......1270-.......1280-------........1290.-.....1300....-..1310......1320.-.....1330..---------....1340......1350-----......1360----......1370......1380......1390......1400......1410......1420......1430......1440......1450......1460......1470......1480......1490......1500......1510......1520......1530......1540...--...1550..----------....1560......1570......1580.-.....1590......---1600......1610......1620....--..1630......1640......1650------........1660......1670......1680......1690......1700......1710
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
MKS
K
F
F
I
G
M
M
T
F
L
L
S
L
I
C
LTGMK
A
E
A
KSVGDISPDDISPEISDNRFQSAE
G
K
V
L
PN
F
E
V
D
M
S
ISDQNN
G
K
L
SIDEDFELTSDG
D
I
I
L
I
GTVQ
G
Q
Y
IQGTPILNENGQLNKIPNRDQ
G
I
I
M
R
VDRTTK
K
V
E
W
A
R
V
V
NYEDGNYNS
Q
Y
A
A
D
K
W
F
S
S
Y
K
SITTNSSK
S
T
F
Y
VG
G
E
V
V
N
Y
YGDSGG
G
S
T
L
I
V
K
S
IDANG
N
F
Q
I
A
H
K
S
Y
VSYGVPSRSD
L
T
Y
A
Y
F
M
D
I
Q
MEG
N
T
L
T
M
SASA
R
Y
A
AQG
K
Q
F
I
R
Y
TLEPA
S
L
S
I
TKNEFNPLD
N
T
F
W
AKYQRT
D
V
L
K
VDNK
G
L
M
A
YNADVNG
A
N
Q
L
K
M
S
I
RESENNY
K
E
I
T
L
F
DS
V
P
E
I
LANSS
P
Y
I
F
M
EDRGDG
N
V
F
V
V
MSTP
T
T
W
Y
I
A
L
V
NI
A
S
E
Q
V
V
E
T
K
K
M
TMNSSTT
L
N
S
V
I
YSEG
K
G
L
L
LGGSTHAEESIFGSEPLNKNN
G
Y
Y
L
A
LGNDLNV
T
D
S
Q
I
L
RTNQHN
S
L
T
T
I
I
N
GVGNKVD
G
F
F
SYDGLNNDG
Y
I
Q
NVEYPNTYDVNPN
G
A
M
I
F
A
E
FNLQPAPVLDTGN
P
I
L
A
F
YQGERRA
D
F
D
E
LEGVKAYSGI
D
S
S
D
V
T
K
S
I
TKNT
F
D
L
Y
T
V
G
V
Q
Q
Q
L
Y
Q
I
E
Y
LPGSGNKTTGT
R
N
V
Q
L
I
HPLETP
K
L
E
K
SYADSHGAFKVGEVVPAN
A
I
H
A
FNGLDSAN
N
V
T
Y
V
V
T
AVDD
E
K
I
T
V
D
A
S
I
KRTEGT
K
T
A
V
I
NK
E
I
-
T
L
M
TSTAD
E
T
A
V
I
D
V
T
S
V
A
L
AAGKYTSLTDVRNEG
H
F
H
I
Y
A
ETMDSVSIDP
K
Y
V
K
LTEDPENPVDWNAP
G
V
Y
Y
V
T
ASLDPASGYTA
K
D
V
K
V
S
V
A
V
V
DV--GS
P
K
V
I
S
V
NMKPYNP
T
T
A
L
V
V
A
EDDING
A
G
V
Y
K
I
N
W
A
I
KDAN
G
L
I
I
QQGVEESG
A
T
I
--
R
VQTPV
P
I
D
L
S
TLNDG
N
Y
T
L
S
V
S
A
A
DRIGHTSEASEK
A
F
T
VDRQA
P
V
V
---TAD
D
K
I
T
Y
E
INTKK
T
E
E
E
F
L
N
DVNVK--TEA
G
A
V
I
-KTNF
D
T
M
V
R
MDSPG
D
Y
T
V
L
V
E
ATDAAGNQ------------SD
P
I
Y
-
V
-------
I
V
TVED--TVAPIISADEAISYNQGN
I
R
T
E
A
L
F
L
T
D
IHATTDEPA
T
I
T
S
D
F
A
D
QVKF-------------------------------DTP
G
V
Y
A
V
T
L
K
ANDISGNQAI----
P
R
-
T
V
N
V
T
I
K
DVTA
P
--
V
ITAD
E
A
I
I
YEKGITK
S
A
T
D
F
L
T
D
----
I
HATTNDGSAITSN
F
A
T
V
-
V
D
LNTPGD
Y
D
V
T
L
SSTDTGGNISD
P
V
T
I
T
V
T
V
R-DTT-P
P
V
I
TAD-
T
T
I
T
Y----EKGTT
K
T
A
A
A
F
L
TDVNATTNDGSAVTSN--FN
P
-------
I
--
S
L
K
Q
V
-
G
T
Y
Q
V
T
L
S
SVDENG
N
Y
A
L
-----
P
V
K
V
T
------
V
V
V
QDTQKPVISSSA
T
S
I
T
YERGEKK---QET
G
-----
F
F
L
D
------
L
A
I
KTD-DGTPVTSD-------FD
T
A
V
NLDTA
G
T
Y
T
V
T
LNSEDESGNK-AD
P
V
-
T
I
---
T
V
T
VADT-EK
P
I
I
--TA----D-------------
T
T
-
I
T
YAK--G
T
T
K
T
V
A
Q
F
L
T
D
I
H-AT-TNDG
S
T
I
IS---------NFDPT
V
L
AQEG
T
Y
-
T
V
V
L
NAKDESNNE-AD
P
V
T
V
T
I
T
V
VDTKG
P
I
-
I
N
A
L
N
A
I
T
Y
ER---------TINKNEA
D
F
L
A
D
I
E
ATTD-----DG
S
T
I
T
TDFN----SKDLDTV
G
T
Y
I
V
T
L
NAEDASGNKAT
P
V
K
V
T
I
K
VEDTIP
P
I
ITADQS
I
T
YERGITK
T
E
Q
A
F
Y
T
D
I
K
AATSDNSPISSDF
S
K
I
D
L
TKTG
N
Y
E
V
L
L
R
ATDQSG
N
K
A
L
P
L
K
I
N
V
L
V
QDTI
A
P
V
I
KTTS
R
E
I
TAERGTPM
T
E
Q
Q
L
L
A
K
IGANTDDG
S
K
I
TTDYN
P
A
I
VNTSG
D
Y
L
V
H
L
Y
A
VDAAGN
Q
A
--
I
P
V
E
I
T
I
H
V
----------KDTTAP
I
I
KADKKISYPVG
T
V
K
T
V
T
E
F
L
Q
-
D
I
HATTDDG
S
K
I
TTD---FDPNMLKTP
G
K
Y
T
I
H
L
N
A
VDADGN
K
A
K
T
--
I
D
V
S
L
T
V
EEKVTPPKPPTPDDGGN--------NTNGSNGTNGSNT
D
I
T
V
NPTKQNTTATNESIPALGDTK
S
T
I
P
V
I
V
G
M
F
L
L
A
T
S
L
V
L
I
RRK
48
Fugue
86.14
25%
-17
- C5 -
4L3A
2
?
A:
[48-516]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
N
V
N
I
P
D
S
T
F
K
A
Y
L
N
G
L
L
G
Q
A
S
T
A
N
I
T
E
A
Q
M
D
S
L
T
Y
I
T
L
A
N
I
N
V
T
D
L
T
G
I
E
Y
A
----
H
N
I
K
D
L
T
I
N
N
I
---
H
A
T
N
Y
N
Q
I
S
G
L
S
N
L
E
R
L
R
I
M
G
A
D
V
T
S
D
K
I
P
N
L
----
S
G
L
T
N
L
T
L
L
D
L
S
H
S
A
H
D
D
S
I
L
T
K
I
N
T
L
P
K
V
T
S
I
D
L
S
Y
N
G
A
I
T
D
I
M
P
L
K
T
M
P
E
L
K
S
L
N
I
Q
F
D
G
V
H
D
Y
R
G
I
E
D
F
P
K
L
N
T
L
L
A
Y
S
--
Q
T
I
G
G
K
K
L
I
N
S
D
I
K
S
S
K
L
T
Y
N
A
E
N
Q
T
L
Y
V
P
F
S
L
M
T
E
R
T
V
N
Y
D
G
Y
V
P
D
F
V
KS
T
A
S
S
D
T
Y
F
T
M
N
E
Q
Q
V
N
G
N
R
L
T
I
T
S
D
G
--
L
T
V
S
D
V
S
-
K
T
D
F
D
N
L
E
K
M
E
Y
N
A
R
I
D
L
S
Y
Q
S
Y
N
T
P
E
Q
F
------------
Q
N
G
G
S
-
Y
T
ISM
P
I
Y
D
H
Y
F
T
V
--
D
H
S
L
N
I
T
A
D
S
E
K
T
Y
I
E
N
Q
L
V
T
E
A
T
F
L
S
D
I
H
A
K
T
D
D
G
S
T
V
T
S
D
F
A
D
K
V
D
F
-------------------------------
N
T
P
G
T
Y
T
V
T
L
Q
S
E
N
N
A
G
L
K
A
T
----
P
V
-
Q
V
N
V
T
I
K
A
--
K
T
--
T
I
T
A
D
E
K
I
T
Y
K
V
D
T
S
K
T
E
A
A
F
L
A
D
----
I
K
A
T
T
N
D
G
T
A
I
T
S
D
F
A
T
V
-
V
D
L
S
K
P
G
K
Y
V
V
T
L
N
A
E
N
D
L
Q
K
-
A
L
P
V
Q
V
M
V
I
V
E
-
K
E
T
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
1
PsiBlast_PDB
71.80
45%
-26
- C4 -
4L3A
1
?
A:
[308-496]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
S
-
K
T
D
F
D
N
L
E
K
M
E
----
Y
N
A
R
I
D
L
S
Y
Q
S
Y
N
T
P
EQFQNG
G
S
Y
T
I
S
M
P
I
Y
D
H
-------
Y
F
T
V
D
H
--
S
L
N
--
I
T
A
D
S
E
K
T
Y
I
E
N
Q
L
V
T
E
A
T
F
L
S
D
I
H
A
K
T
D
D
G
S
T
V
T
S
D
F
A
D
K
V
D
F
-------------------------------
N
T
P
G
T
Y
T
V
T
L
Q
S
E
N
N
A
G
L
K
A
T
----
P
V
-
Q
V
N
V
T
I
K
A
K
T
----
T
I
T
A
D
E
K
I
T
Y
K
V
D
T
S
K
T
E
A
A
F
L
A
D
----
I
K
A
T
T
N
D
G
T
A
I
T
S
D
F
A
T
V
-
V
D
L
S
K
P
G
K
Y
V
V
T
L
N
A
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
56
Fugue
63.82
24%
23
- C5 -
2YN5
5
?
A:
[1-283]
----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
T
P
P
N
A
P
V
V
T
Y
S
-
D
I
V
-
N
D
L
I
I
M
Q
-
G
T
----------
A
E
A
K
S
Q
L
I
I
T
D
S
E
G
N
T
Y
T
L
T
V
P
D
N
G
--
K
W
S
-------
M
--
A
I
P
Y
P
-
S
E
G
K
F
T
I
T
S
V
D
A
I
G
N
R
S
D
-----
D
V
P
L
D
------
I
M
---
K
E
V
P
V
I
S
L
S
P
D
S
D
S
G
T
V
G
D
N
I
TRD
K
Q
P
T
-----
F
I
I
G
NLESDV
V
V
V
Q
V
D
I
N
G
T
V
Y
N
A
E
K
N
ADG
V
W
F
F
T
P
G
T
P
L
A
D
G
S
Y
T
I
S
V
I
A
S
D
A
A
G
N
Q
-
K
N
S
L
-
P
I
---
T
V
T
I
D
S
T
L
T
V
P
E
I
--
A
L
----
A
AGEDNGASDSDNV
T
N
-
H
T
Q
P
K
--
F
T
L
Q
H
I
D
A
D
V
T
G
V
T
-
V
N
V
T
H
N
G
V
T
D
I
Y
Q
A
T
Q
G
AD
G
W
T
F
T
P
P
A
A
W
N
D
G
N
Y
-
T
L
S
V
T
V
V
D
R
A
G
N
S
-
Q
Q
S
A
S
L
A
V
T
V
D
S
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
14
PsiBlast_PDB
63.03
23%
33
- C4 -
4P99
20
?
A:
[73-417]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E
----
T
Y
T
T
T
V
D
A
N
G
E
W
S
V
D
V
A
G
-
S
D
L
A
A
D
T
A
F
D
A
V
V
T
S
S
D
A
A
G
N
T
V
D
T
T
G
S
S
T
H
T
V
-
D
T
E
-
A
T
A
G
T
V
T
V
N
A
I
T
S
----
D
D
V
I
N
A
S
E
A
A
G
T
V
A
V
S
G
T
A
T
G
G
D
I
A
E
G
----
D
T
-------
V
--
T
L
E
I
N
-
G
E
T
Y
T
T
--
T
V
D
A
N
G
E
W
S
V
-----
D
V
A
G
S
------
D
L
A
A
D
T
A
F
D
A
V
V
T
S
S
--------------------------
D
------
A
A
G
N
T
V
-
D
T
T
--
G
S
S
-------
T
H
T
V
D
T
E
A
T
A
G
T
V
T
V
N
A
I
T
S
D
D
V
I
N
A
-
S
E
A
A
G
T
V
---
A
V
S
G
T
A
T
-
G
G
D
I
A
--
E
G
----
D
-------------
T
V
-
T
L
E
I
N
--
G
E
T
Y
T
----------
T
T
-
V
D
A
N
G
E
W
S
V
---------
D
V
A
G
S
D
L
A
A
D
T
A
F
-
D
A
V
V
T
S
S
D
A
A
G
N
T
-
V
D
T
T
G
S
S
T
H
T
V
D
T
E
A
T
A
G
T
V
T
V
N
A
I
T
S
D
D
---------
V
I
N
A
S
E
A
A
G
T
V
A
V
S
G
T
A
T
G
G
DIA
E
G
D
T
V
T
L
E
I
N
G
E
T
Y
T
T
T
V
D
A
N
G
E
W
S
V
D
V
A
G
S
D
L
A
A
D
T
A
F
D
A
V
V
T
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
21
PsiBlast_CBE
60.33
45%
29
- C4 -
4L3A
1
?
B:
[308-440]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
V
S
-
K
T
D
F
D
N
L
E
K
M
E
----
Y
N
A
R
I
D
L
S
Y
Q
S
Y
N
T
P
EQFQNG
G
S
Y
T
I
S
M
P
I
Y
D
H
-------
Y
F
T
V
D
H
--
S
L
N
--
I
T
A
D
S
E
K
T
Y
I
E
N
Q
L
V
T
E
A
T
F
L
S
D
I
H
A
K
T
D
D
G
S
T
V
T
S
D
F
A
D
K
V
D
F
-------------------------------
N
T
P
G
T
Y
T
V
T
L
Q
S
E
N
N
A
G
L
K
A
T
----
P
V
-
Q
V
N
V
T
I
K
A
K
T
----
T
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
54
Fugue
53.07
12%
-7
* C6 *
1L3W
26
CADHF_XENLA
A:
[7-546]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
D
W
V
I
P
P
I
K
V
S
E
N
E
R
G
P
F
P
K
R
L
V
Q
I
K
S
N
K
---
D
R
F
N
K
V
Y
Y
S
I
T
G
Q
G
A
D
N
P
P
Q
G
V
F
R
I
E
--
W
E
T
G
W
M
L
V
T
R
P
L
D
R
----
E
E
Y
D
K
Y
V
L
S
S
H
A
V
S
E
N
G
S
P
V
-----------
E
E
P
M
E
-
I
-------
T
I
N
V
I
D
Q
N
D
N
R
P
K
F
T
Q
D
V
F
R
G
S
V
R
E
G
V
Q
P
G
T
Q
V
M
A
-
V
S
A
T
D
E
D
D
N
I
D
S
L
N
G
V
L
S
Y
S
I
L
K
QDPEEPIPNLFTINRETG
V
I
S
L
IGTGLDR
E
K
F
P
E
Y
T
L
T
V
Q
A
T
D
L
E
G
A
G
L
S
----
V
E
G
K
A
I
I
Q
I
T
D
A
N
D
N
--
A
P
I
F
D
P
K
T
Y
T
A
L
V
P
E
N
E
I
G
F
E
V
Q
R
----
L
S
V
T
D
L
D
M
P
G
T
P
A
W
Q
A
V
Y
K
I
R
V
N
E
G
G
F
F
N
I
T
T
D
P
E
S
N
Q
G
I
L
T
T
A
K
G
L
D
F
E
L
R
-
K
Q
Y
-
V
L
Q
I
T
V
E
-
N
A
E
P
F
----
S
V
P
L
P
T
S
T
A
T
V
T
V
T
V
E
D
V
N
E
A
P
F
F
V
P
A
V
--
S
R
V
-------
D
VS
E
D
L
S
R
-
G
E
K
I
I
S
L
V
A
Q
D
P
D
K
Q
Q
I
Q
-----
K
L
S
Y
F
------
I
G
N
D
P
A
R
W
L
T
V
N
K
D
N
G
I
V
T
G
N
G
N
L
D
R
---
E
S
E
Y
VKNN
T
Y
T
V
I
------
M
L
V
T
D
D
-
G
V
S
V
G
T
G
T
-------
G
T
L
I
L
H
V
L
D
V
N
D
N
G
P
V
P
S
P
R
V
F
T
M
C
D
-
Q
N
P
E
-
P
Q
---
V
L
T
I
S
D
A
-
D
I
P
P
N
--
T
Y
----
P
-------------
Y
K
-
V
S
L
S
H
--
G
S
D
L
T
W
-----
K
A
E
-
L
D
-
S
K
G
T
S
M
L
L
S
---------
P
T
Q
Q
L
---
K
K
G
D
Y
-
S
I
Y
V
L
L
S
D
-
A
Q
N
N
-
P
Q
L
T
V
V
N
A
T
V
C
S
C
E
G
K
A
-
I
K
C
Q
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
49
Fugue
52.83
12%
17
- C5 -
2C4X
5
?
A:
[5-254]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
E
N
Q
A
P
K
A
I
F
T
F
S
-
P
E
D
P
V
T
D
-
E
N
V
V
F
----
N
A
S
N
S
I
D
E
D
G
T
I
A
Y
Y
V
W
D
F
G
D
G
Y
E
G
T
S
T
TP
T
I
T
-------
Y
--
K
Y
K
N
P
-
G
T
Y
K
V
K
L
I
V
T
D
N
Q
G
A
-
S
S
-----
S
F
T
A
T
------
I
K
V
T
S
A
T
G
D
N
S
K
F
N
F
E
D
---
G
T
L
G
G
F
---
T
T
S
G
-----
T
N
A
T
------
G
V
V
V
N
T
-
T
E
K
A
F
K
G
E
-------
R
G
L
K
W
T
V
T
S
E
G
E
G
T
A
E
L
K
L
D
G
G
T
I
V
V
-
P
G
T
T
M
T
F
---
R
I
W
I
P
S
G
-
A
P
I
A
A
--
I
Q
----
P
-------------
Y
I
M
P
H
T
P
D
--
W
S
E
V
L
W
N
S
T
W
K
G
Y
T
M
V
K
-
T
D
D
W
N
E
I
T
L
---------
T
L
P
E
D
V
D
P
T
W
P
Q
Q
M
G
I
Q
V
Q
T
I
D
E
------
G
E
F
T
I
Y
V
D
A
I
D
W
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
52
Fugue
51.91
11%
28
* C5 *
2C26
14
?
A:
[5-254]
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
P
E
N
Q
A
P
K
A
I
F
T
F
S
-
P
E
D
P
V
T
D
-
E
N
V
V
F
----
N
A
S
N
S
I
D
E
D
G
T
I
A
Y
Y
V
W
D
F
G
D
G
Y
E
G
T
S
T
TP
T
I
T
-------
Y
--
K
Y
K
N
P
-
G
T
Y
K
V
K
L
I
V
T
D
N
Q
G
A
-
S
S
-----
S
F
T
A
T
------
I
K
V
T
S
A
T
G
D
N
S
K
F
N
F
E
D
---
G
T
L
G
G
F
---
T
T
S
G
-----
T
N
A
T
------
G
V
V
V
N
T
-
T
E
K
A
F
K
G
E
-------
R
G
L
K
W
T
V
T
S
E
G
E
G
T
A
E
L
K
L
D
G
G
T
I
V
V
-
P
G
T
T
-
M
T
---
F
R
I
W
I
P
S
-
G
A
P
I
A
--
A
I
----
Q
-------------
P
Y
-
I
M
P
H
T
PD
W
S
E
V
L
W
N
S
T
W
K
G
Y
T
-
M
V
-
K
T
D
D
W
N
E
I
T
---------
L
T
L
P
E
D
V
D
P
T
W
P
Q
-
Q
M
G
I
Q
V
Q
T
I
D
E
G
----
E
F
T
I
Y
V
D
A
I
D
W
L
E
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
25
HHSearch
49.66
21%
67
- C4 -
3PDD
4
?
A:
[59-177]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
A
V
G
A
Y
N
L
K
A
V
A
V
L
S
D
G
R
R
I
E
S
P
V
T
P
V
L
V
K
V
I
--
V
K
P
T
V
K
L
T
A
P
K
S
--
N
--
V
V
A
Y
G
------
N
E
F
L
K
I
T
A
T
A
S
D
S
D
G
K
I
S
R
V
D
F
L
V
D
G
E
V
I
GS
D
R
E
A
P
Y
E
Y
E
W
K
-
A
V
E
G
N
H
E
I
S
V
I
A
Y
D
D
D
D
A
A
S
T
P
D
S
V
K
I
F
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
15
PsiBlast_PDB
48.72
27%
71
- C4 -
4M00
2
SRAP_STAA8
A:
[365-531]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
-
A
P
T
V
-
T
V
G
N
Q
T
I
E
V
G
K
T
-
M
N
P
I
V
L
T
T
T
----
D
-------------
N
G
-
T
G
T
V
T
--
N
T
V
T
G
L
P
S
G
L
S
Y
D
S
-
A
T
-----
N
S
I
I
G
---------
T
--
P
T
K
I
G
Q
S
----
T
V
T
V
V
S
T
D
Q
A
N
N
K
-
S
T
-
T
T
F
T
I
N
V
V
D
T
T
A
P
T
-
V
T
P
I
G
D
Q
S
S
E
V
YSPIS
P
I
K
I
A
T
Q
D
N
S
G
N
A
V
T
N
T
V
T
G
L
P
-----
S
G
L
T
F
D
S
T
N
N
T
I
--
S
G
T
P
T
N
I
G
T
S
T
I
S
I
V
S
T
D
A
S
G
N
K
T
T
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
3
PsiBlast_PDB
47.62
26%
142
- C4 -
2YN5
4
?
A:
[64-186]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
T
S
V
D
A
I
G
N
R
S
D
D
V
P
L
D
I
M
K
E
V
P
V
I
S
L
SPDSD
S
G
T
V
G
D
N
I
T
R
D
K
Q
P
T
F
I
I
G
N
L
E
S
D
V
V
V
V
Q
V
D
I
N
G
T
V
Y
N
A
E
K
N
A
D
G
V
W
F
F
T
P
G
T
P
L
A
D
G
S
Y
T
I
S
V
I
A
S
D
A
A
G
N
Q
K
N
S
--
L
P
I
T
V
T
I
D
S
T
L
T
V
P
E
-----------------------------------------------------------------------------
51
Fugue
46.54
14%
6
- C5 -
4E9L
-
?
A:
[678-991]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F
V
A
G
P
L
D
A
A
H
S
S
I
T
L
N
P
D
K
P
---
V
V
G
G
T
V
T
A
I
W
T
A
K
D
A
N
D
N
P
V
T
G
L
N
P
D
A
P
S
L
S
G
A
A
A
-
A
G
S
T
A
S
G
W
T
D
N
G
D
G
T
W
T
A
Q
I
S
L
----
G
T
T
------------
A
G
E
L
D
-
V
-------
M
P
K
L
N
G
--
Q
D
A
A
A
N
A
A
K
V
T
V
V
A
D
A
L
S
S
N
Q
S
K
V
S
V
A
E
D
H
V
K
A
G
E
S
T
T
V
T
L
V
A
K
D
A
--------------------------------------------
H
G
N
A
I
S
G
L
S
L
S
----
A
S
-
L
T
G
T
A
S
E
G
A
T
V
S
--
S
W
T
E
K
G
D
G
S
Y
V
A
T
L
T
T
G
G
K
T
G
E
L
R
----
V
M
P
L
F
N
G
Q
P
A
A
T
E
A
A
Q
L
T
-
V
I
A
G
E
M
S
S
A
N
S
T
L
V
A
D
N
K
T
P
T
V
K
T
T
T
E
L
T
F
T
M
K
-
D
A
Y
G
N
P
V
T
G
L
K
-
P
D
A
P
V
----
F
S
G
A
A
S
T
G
S
E
R
P
S
A
G
N
W
T
E
K
G
N
G
V
Y
V
S
T
--
L
T
L
-------
G
--
S
A
A
G
Q
-
L
S
V
M
P
R
V
-----
N
G
Q
N
A
V
-----
A
Q
P
L
V
------
L
N
V
A
G
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
17
PsiBlast_PDB
46.40
28%
288
- C7 -
3MV7
1
?
D:
[36-128]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
D
P
G
K
G
P
E
F
L
F
T
L
Y
S
A
G
E
E
K
E
K
ER
L
K
A
T
L
T
K
K
E
S
F
L
H
I
T
A
P
K
P
E
D
S
A
T
Y
L
C
A
V
Q
D
L
G
T
S
G
S
R
L
T
F
G
E
G
T
Q
L
T
V
N
P
N
I
Q
N
---
P
D
P
A
V
Y
Q
L
R
D
S
K
S
S
--------------------
20
PsiBlast_PDB
46.10
28%
292
- C7 -
4PRP
1
TCA_HUMAN
D:
[36-128]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
D
P
G
K
G
P
E
F
L
F
T
L
Y
S
A
G
E
E
K
E
K
ER
L
K
A
T
L
T
K
K
E
S
F
L
H
I
T
A
P
K
P
E
D
S
A
T
Y
L
C
A
V
Q
D
L
G
T
S
G
S
R
L
T
F
G
E
G
T
Q
L
T
V
N
P
N
I
Q
N
---
P
D
P
A
V
Y
Q
L
R
D
S
K
S
S
--------------------
18
PsiBlast_PDB
46.09
28%
302
- C7 -
3MV8
1
?
D:
[36-128]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
D
P
G
K
G
P
E
F
L
F
T
L
Y
S
A
G
E
E
K
E
K
ER
L
K
A
T
L
T
K
K
E
S
F
L
H
I
T
A
P
K
P
E
D
S
A
T
Y
L
C
A
V
Q
D
L
G
T
S
G
S
R
L
T
F
G
E
G
T
Q
L
T
V
N
P
N
I
Q
N
---
P
D
P
A
V
Y
Q
L
R
D
S
K
S
S
--------------------
2
PsiBlast_PDB
46.03
26%
134
- C4 -
2YN3
4
?
A:
[64-195]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I
T
S
V
D
A
I
G
N
R
S
D
D
V
P
L
D
I
M
K
E
V
P
V
I
S
L
SPDSD
S
G
T
V
G
D
N
I
T
R
D
K
Q
P
T
F
I
I
G
N
L
E
S
D
V
V
V
V
Q
V
D
I
N
G
T
V
Y
N
A
E
K
N
A
D
G
V
W
F
F
T
P
G
T
P
L
A
D
G
S
Y
T
I
S
V
I
A
S
D
A
A
G
N
Q
K
N
S
--
L
P
I
T
V
T
I
D
S
T
L
T
V
P
E
-----------------------------------------------------------------------------
53
Fugue
45.84
10%
7
- C5 -
3UBF
19
A:
[1-312]
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
S
A
V
R
P
T
K
R
I
E
F
T
E
A
D
G
D
T
------------
E
G
K
---
S
-------
V
F
Q
L
E
K
--
E
T
D
K
E
T
F
K
I
R
D
D
N
P
W
V
T
V
E
T
N
G
A
V
R
V
K
K
K
W
D
Y
E
E
L
G
P
E
K
T
I
D
F
W
V
I
I
T
N
-------------------------------
K
Y
T
D
N
Q
R
V
I
I
L
V
K
D
V
N
D
E
P
P
Y
F
INR
P
L
-
P
M
Q
A
V
V
Q
L
N
A
P
P
NT
P
V
F
T
L
Q
A
R
D
P
D
T
D
H
N
I
H
Y
F
I
V
R
D
R
TGGR
F
E
V
D
E
R
S
G
V
V
R
T
R
G
---
T
-
D
L
F
Q
L
D
M
E
Y
V
L
Y
V
K
A
E
D
Q
N
G
Q
S
T
P
E
E
R
L
S
I
V
G
G
-
K
R
A
-
P
Q
F
Y
M
P
S
-
Y
E
A
E
I
----
P
E
N
Q
K
K
--
D
S
D
I
I
S
I
K
A
K
S
F
A
D
R
E
I
R
Y
T
--
L
K
A
QGQGAGT
F
--
N
I
G
P
T
S
G
I
V
K
L
A
K
E
L
D
F
E
D
L
R
Q
P
H
-----
V
Y
S
L
I
------
V
T
A
T
E
D
S
G
G
F
S
T
S
V
D
L
T
I
R
V
T
D
V
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
19
PsiBlast_PDB
45.83
28%
291
* C7 *
3MV9
2
?
D:
[36-128]
---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Q
D
P
G
K
G
P
E
F
L
F
T
L
Y
S
A
G
E
E
K
E
K
ER
L
K
A
T
L
T
K
K
E
S
F
L
H
I
T
A
P
K
P
E
D
S
A
T
Y
L
C
A
V
Q
D
L
G
T
S
G
S
R
L
T
F
G
E
G
T
Q
L
T
V
N
P
N
I
Q
N
---
P
D
P
A
V
Y
Q
L
R
D
S
K
S
S
--------------------
55
Fugue
44.85
11%
17
- C6 -
3B2M
-
PILIN_STRP1
A:
[14-307]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
G
P
G
S
A
T
T
V
H
G
E
T
-
V
V
N
G
A
K
L
T
V
T
K
N
L
D
L
V
N
S
N
A
L
I
P
N
-
T
D
F
T
F
K
I
E
-
P
D
T
-
T
V
N
E
D
-
G
-
N
K
F
K
G
----
V
A
L
N
T
P
M
T
K
V
T
Y
T
N
S
D
K
G
G
S
N
T
K
T
A
E
F
D
--
F
S
E
-------
V
--
T
F
E
K
P
-
G
V
Y
Y
Y
K
V
T
E
E
K
I
D
K
V
P
G
V
S
Y
D
T
T
S
Y
T
V
Q
------
V
H
V
L
W
N
E
E
Q
Q
K
P
V
A
T
Y
I
V
G
Y
K
E
G
S
K
V
---
P
--------
I
Q
F
K
------
N
S
L
D
S
T
-
T
L
T
V
K
K
K
V
-------
S
G
T
G
G
D
R
S
K
D
F
N
F
G
L
T
L
K
A
N
Q
Y
Y
K
A
S
-
E
K
V
M
-
I
E
---
K
T
T
K
G
G
Q
-
A
P
V
Q
T
--
E
A
S
I
D
Q
L
-------------
Y
H
-
F
T
L
K
D
--
G
E
S
I
K
V
T
N
L
P
V
G
V
D
-
Y
V
-
V
T
E
D
D
Y
K
S
E
---------
K
Y
T
T
N
V
E
V
S
P
Q
D
G
-
A
V
K
N
I
A
G
N
S
T
E
Q
E
T
S
T
D
K
D
M
T
I
T
F
T
N
K
K
V
F
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
57
Fugue
43.55
11%
14
- C5 -
3RJD
7
FCGR1_HUMAN
A:
[1-262]
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
K
A
V
I
T
L
Q
P
P
W
V
S
--
V
F
Q
E
E
T
V
T
L
H
C
E
V
L
H
L
P
G
S
S
S
T
Q
W
----
F
L
N
G
T
A
T
Q
T
S
T
P
S
Y
R
I
T
S
-
A
S
V
N
D
S
G
E
Y
R
C
Q
R
G
L
S
G
R
S
D
P
I
Q
L
E
I
H
R
G
W
L
L
L
-
Q
V
S
-
S
R
V
F
T
E
G
-
E
P
L
A
L
R
CHA
W
K
D
K
L
V
Y
N
V
L
Y
Y
R
N
G
K
A
F
K
F
F
H
W
N
S
N
L
T
--
I
L
K
-------
T
--
N
I
S
H
N
-
G
T
Y
H
C
S
G
M
G
K
H
R
Y
T
S
A
G
I
-----
S
V
T
V
K
E
LF
P
A
P
V
L
N
A
S
V
T
S
P
L
L
E
G
N
L
V
T
L
S
C
E
T
K
L
L
L
---
Q
L
Y
F
-----
S
F
Y
M
------
G
S
K
T
L
R
-
G
R
N
T
S
S
E
Y
-------
Q
I
L
T
A
R
R
E
D
S
G
L
Y
W
C
E
A
A
T
E
D
G
N
V
L
K
R
S
P
E
L
-
E
L
---
Q
V
L
G
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------