@TOME V2.3
(Nov 2016)
Ref.
-
-
Doc.
Global output mode :
Sort entries by :
Atome Result
Tools Result
PDB occurence
Core Structure Cluster
Sequence Color type :
Secondary Structure
Hydrophobicity
Disulfide Bonds
TCoffee Identity Score
Uniprot annotation
Core Structure Cluster
Contacts with Ligands
Show alignment :
Atome selection
All alignments
Only Template with Ligand
Column output:
Score:
Atome Rank Value
Tools Score
Hide column
Alignment:
Sequence Identity (%)
Tcoffee Alignment Score
Hide column
3D Common Core:
Tito PKB Score
Verify3D Score
QMean Score
Hide column
Structural Clustering:
Cluster Num
3D-Jury Struct. Score
Hide column
Modeller Result :
Model Rank
QMean Score
Dfire Score
Dope Score
Errat Score
Verify3D Score
Modeller Score
Hide column
Complexes Modeling
Show Ligands of Templates
Complexes Affinity Score
Main Binding Site Identity
Hide column
Templates Information:
Uniprot entry
Cath class
Scop class
Smart class
Prosite class
Pfam class
EC Number
Taxonomy
Experiment Method
Hide column
Sequence & Result Tab:
PDB Template Sequence
Complexes Tab
Values color: [
Good
|
Correct
|
Middling
|
Bad
]
Sequence color :
Mutated
Helix
Strand
Conserved
Query sequence : Lmo1688: (2016-03-27 )
MNKVALVTGSSRGLGREIAIALAKEGYDIAVNFSRNRKKAEEVQQEIEQLGRKCVIFKANVGDVEKVRELFKAVDEEFGRLDIFINNAASGVLRPLMELEESHWDWTMNINAKALLFAGQEAAKLMQRHQSGKIISLSSIGSIRYLENYTTVGVSKAAVESLTRYLAVELAPFGIAVNAVSGGLIETDALNHFPNREELLKDAVSKTPAGRMIEPNDLVNAVLFLASEKADMIRGQTILVDGGRTLLV
Atome Classification :
(22 SA)
.........10........20........-30........40......-.-.50........60........70........80........90..---.--.--....100.......110.......120..-.....130.......-140-----.....--....150.......160.......170.......180......-.190----........200------..-.....210.......220.......230.......240......
(Atome)
(Ident)
(Tito)
(Num)
(Ligand)
(Uniprot)
M
N
K
V
A
L
V
TGSSRGL
G
R
E
I
A
I
A
LAKE
G
Y
D
I
-
A
V
N
FSRNR
K
K
A
E
E
V
Q
Q
E
I
-
E
-
Q
LGR
K
C
V
I
F
KANVG
D
V
E
K
V
R
E
L
F
K
A
V
D
E
EFG
R
L
D
I
F
INNA
A
S
G
V
L
---
R
--
P
--
L
M
E
L
E
ESHW
D
W
T
M
NIN
A
K
A
L
L
FA
G
Q
E
A
A
K
-
L
M
Q
R
HQSG
K
I
I
S
L
SS-I-------
G
S
I
R
Y
--LENYTTVG
V
S
K
A
A
V
E
S
L
T
R
Y
L
A
VELAP
F
G
I
A
V
N
AVSGGLIE
T
D
-
A
LN-----HFP
N
R
E
E
L
L
K
D
------
A
V
-SKTPAGRMI
E
P
N
D
L
V
N
A
V
L
F
L
ASE
K
A
D
MIRG
Q
T
I
L
V
DG
G
R
T
L
LV
22
PsiBlast_CBE
92.17
69%
-89
- C1 -
3OID
2
FABL_BACSU
C:
[4-250]
-
N
K
C
A
L
V
T
G
S
S
R
G
V
G
K
A
A
A
I
R
L
A
E
N
G
Y
N
I
-
V
I
N
Y
A
R
S
K
K
A
A
L
E
T
A
E
E
I
-
E
-
K
L
G
V
K
V
L
V
V
K
A
N
V
G
Q
P
A
K
I
K
E
M
F
Q
Q
I
D
E
T
F
G
R
L
D
V
F
V
N
N
A
A
S
G
V
L
---
R
--
P
--
V
M
E
L
E
E
T
H
W
D
W
T
M
N
I
N
A
K
A
L
L
F
C
A
Q
E
A
A
K
-
L
M
E
K
N
G
G
G
H
I
V
S
I
S
S
-
L
-------
G
S
I
R
Y
--
L
E
N
Y
T
T
V
G
V
S
K
A
A
L
E
A
L
T
R
Y
L
A
V
E
L
S
P
K
Q
I
I
V
N
A
V
S
G
G
A
I
D
T
D
-
A
L
K
-----
H
F
P
N
R
E
D
L
L
E
D
------
A
R
-
Q
N
T
P
A
G
R
M
V
E
I
K
D
M
V
D
T
V
E
F
L
V
S
S
K
A
D
M
I
R
G
Q
T
I
I
V
D
G
G
R
S
L
L
V
23
PsiBlast_CBE
90.93
69%
-88
- C1 -
3OID
2
FABL_BACSU
B:
[4-250]
-
N
K
C
A
L
V
T
G
S
S
R
G
V
G
K
A
A
A
I
R
L
A
E
N
G
Y
N
I
-
V
I
N
Y
A
R
S
K
K
A
A
L
E
T
A
E
E
I
-
E
-
K
L
G
V
K
V
L
V
V
K
A
N
V
G
Q
P
A
K
I
K
E
M
F
Q
Q
I
D
E
T
F
G
R
L
D
V
F
V
N
N
A
A
S
G
V
L
---
R
--
P
--
V
M
E
L
E
E
T
H
W
D
W
T
M
N
I
N
A
K
A
L
L
F
C
A
Q
E
A
A
K
-
L
M
E
K
N
G
G
G
H
I
V
S
I
S
S
-
L
-------
G
S
I
R
Y
--
L
E
N
Y
T
T
V
G
V
S
K
A
A
L
E
A
L
T
R
Y
L
A
V
E
L
S
P
K
Q
I
I
V
N
A
V
S
G
G
A
I
D
T
D
-
A
L
K
-----
H
F
P
N
R
E
D
L
L
E
D
------
A
R
-
Q
N
T
P
A
G
R
M
V
E
I
K
D
M
V
D
T
V
E
F
L
V
S
S
K
A
D
M
I
R
G
Q
T
I
I
V
D
G
G
R
S
L
L
V
24
PsiBlast_CBE
90.83
69%
-99
- C1 -
3OIC
1
FABL_BACSU
D:
[4-250]
-
N
K
C
A
L
V
T
G
S
S
R
G
V
G
K
A
A
A
I
R
L
A
E
N
G
Y
N
I
-
V
I
N
Y
A
R
S
K
K
A
A
L
E
T
A
E
E
I
-
E
-
K
L
G
V
K
V
L
V
V
K
A
N
V
G
Q
P
A
K
I
K
E
M
F
Q
Q
I
D
E
T
F
G
R
L
D
V
F
V
N
N
A
A
S
G
V
L
---
R
--
P
--
V
M
E
L
E
E
T
H
W
D
W
T
M
N
I
N
A
K
A
L
L
F
C
A
Q
E
A
A
K
-
L
M
E
K
N
G
G
G
H
I
V
S
I
S
S
-
L
-------
G
S
I
R
Y
--
L
E
N
Y
T
T
V
G
V
S
K
A
A
L
E
A
L
T
R
Y
L
A
V
E
L
S
P
K
Q
I
I
V
N
A
V
S
G
G
A
I
D
T
D
-
A
L
K
-----
H
F
P
N
R
E
D
L
L
E
D
------
A
R
-
Q
N
T
P
A
G
R
M
V
E
I
K
D
M
V
D
T
V
E
F
L
V
S
S
K
A
D
M
I
R
G
Q
T
I
I
V
D
G
G
R
S
L
L
V
21
PsiBlast_CBE
90.63
69%
-86
- C1 -
3OID
2
FABL_BACSU
D:
[4-250]
-
N
K
C
A
L
V
T
G
S
S
R
G
V
G
K
A
A
A
I
R
L
A
E
N
G
Y
N
I
-
V
I
N
Y
A
R
S
K
K
A
A
L
E
T
A
E
E
I
-
E
-
K
L
G
V
K
V
L
V
V
K
A
N
V
G
Q
P
A
K
I
K
E
M
F
Q
Q
I
D
E
T
F
G
R
L
D
V
F
V
N
N
A
A
S
G
V
L
---
R
--
P
--
V
M
E
L
E
E
T
H
W
D
W
T
M
N
I
N
A
K
A
L
L
F
C
A
Q
E
A
A
K
-
L
M
E
K
N
G
G
G
H
I
V
S
I
S
S
-
L
-------
G
S
I
R
Y
--
L
E
N
Y
T
T
V
G
V
S
K
A
A
L
E
A
L
T
R
Y
L
A
V
E
L
S
P
K
Q
I
I
V
N
A
V
S
G
G
A
I
D
T
D
-
A
L
K
-----
H
F
P
N
R
E
D
L
L
E
D
------
A
R
-
Q
N
T
P
A
G
R
M
V
E
I
K
D
M
V
D
T
V
E
F
L
V
S
S
K
A
D
M
I
R
G
Q
T
I
I
V
D
G
G
R
S
L
L
V
2
PsiBlast_PDB
90.63
69%
-88
- C1 -
3OID
2
FABL_BACSU
A:
[4-250]
-
N
K
C
A
L
V
T
G
S
S
R
G
V
G
K
A
A
A
I
R
L
A
E
N
G
Y
N
I
-
V
I
N
Y
A
R
S
K
K
A
A
L
E
T
A
E
E
I
-
E
-
K
L
G
V
K
V
L
V
V
K
A
N
V
G
Q
P
A
K
I
K
E
M
F
Q
Q
I
D
E
T
F
G
R
L
D
V
F
V
N
N
A
A
S
G
V
L
---
R
--
P
--
V
M
E
L
E
E
T
H
W
D
W
T
M
N
I
N
A
K
A
L
L
F
C
A
Q
E
A
A
K
-
L
M
E
K
N
G
G
G
H
I
V
S
I
S
S
-
L
-------
G
S
I
R
Y
--
L
E
N
Y
T
T
V
G
V
S
K
A
A
L
E
A
L
T
R
Y
L
A
V
E
L
S
P
K
Q
I
I
V
N
A
V
S
G
G
A
I
D
T
D
-
A
L
K
-----
H
F
P
N
R
E
D
L
L
E
D
------
A
R
-
Q
N
T
P
A
G
R
M
V
E
I
K
D
M
V
D
T
V
E
F
L
V
S
S
K
A
D
M
I
R
G
Q
T
I
I
V
D
G
G
R
S
L
L
V
1
PsiBlast_PDB
88.45
69%
-105
- C1 -
3OIC
-
FABL_BACSU
A:
[4-250]
-
N
K
C
A
L
V
T
G
S
S
R
G
V
G
K
A
A
A
I
R
L
A
E
N
G
Y
N
I
-
V
I
N
Y
A
R
S
K
K
A
A
L
E
T
A
E
E
I
-
E
-
K
L
G
V
K
V
L
V
V
K
A
N
V
G
Q
P
A
K
I
K
E
M
F
Q
Q
I
D
E
T
F
G
R
L
D
V
F
V
N
N
A
A
S
G
V
L
---
R
--
P
--
V
M
E
L
E
E
T
H
W
D
W
T
M
N
I
N
A
K
A
L
L
F
C
A
Q
E
A
A
K
-
L
M
E
K
N
G
G
G
H
I
V
S
I
S
S
-
L
-------
G
S
I
R
Y
--
L
E
N
Y
T
T
V
G
V
S
K
A
A
L
E
A
L
T
R
Y
L
A
V
E
L
S
P
K
Q
I
I
V
N
A
V
S
G
G
A
I
-------------
F
P
N
R
E
D
L
L
E
D
------
A
R
-
Q
N
T
P
A
G
R
M
V
E
I
K
D
M
V
D
T
V
E
F
L
V
S
S
K
A
D
M
I
R
G
Q
T
I
I
V
D
G
G
R
S
L
L
V
27
PsiBlast_CBE
74.27
41%
-81
- C1 -
4JRO
1
?
C:
[30-271]
--
K
V
A
V
V
T
G
G
S
R
G
I
G
R
D
I
A
I
N
L
A
K
E
G
A
N
I
-
F
F
N
Y
N
G
S
P
E
A
A
E
E
T
A
K
L
V
-
A
-
E
H
G
V
E
V
E
A
M
K
A
N
V
A
I
A
E
D
V
D
A
F
F
K
Q
A
I
E
R
F
G
R
V
D
I
L
V
N
N
A
--
G
I
T
---
R
--
D
NL
L
M
R
M
K
E
D
E
W
D
D
V
I
N
I
N
L
K
G
T
F
L
C
T
K
A
V
S
R
-
T
M
M
K
Q
R
A
G
K
I
I
N
M
A
S
-
V
-------
V
G
L
I
G
--
N
A
G
Q
A
N
Y
V
A
S
K
A
G
V
I
G
L
T
K
T
T
A
R
E
L
A
P
R
G
I
N
V
N
A
V
A
P
G
F
I
T
T
D
-
M
T
D
-----
K
L
---
D
E
K
T
K
E
------
A
M
L
A
Q
I
P
L
G
A
Y
G
T
T
E
D
I
A
N
A
V
L
F
L
A
S
D
A
S
K
Y
I
T
G
Q
T
L
S
V
D
G
G
M
V
M
--
6
PsiBlast_PDB
73.15
40%
-88
- C1 -
3OSU
15
FABG_STAAM
A:
[5-243]
--
K
S
A
L
V
T
G
A
S
R
G
I
G
R
S
I
A
L
Q
L
A
E
E
G
Y
N
V
-
A
V
N
Y
A
G
S
K
E
K
A
E
A
V
V
E
E
I
-
K
-
A
K
G
V
D
S
F
A
I
Q
A
N
V
A
D
A
D
E
V
K
A
M
I
K
E
V
V
S
Q
F
G
S
L
D
V
L
V
N
N
A
--
G
I
T
---
R
--
D
NL
L
M
R
M
K
E
Q
E
W
D
D
V
I
D
T
N
L
K
G
V
F
N
C
I
Q
K
A
T
P
-
Q
M
L
R
Q
R
S
G
A
I
I
N
L
S
S
-
V
VGA
V
G
N
P
G
Q
A
N
Y
--
V
-------
A
T
K
A
G
V
I
G
L
T
K
S
A
A
R
E
L
A
S
R
G
I
T
V
N
A
V
A
P
G
F
I
V
S
D
-
M
T
D
-----
A
L
S
--
D
E
L
K
E
Q
------
M
L
-
T
Q
I
P
L
A
R
F
G
Q
D
T
D
I
A
N
T
V
A
F
L
A
S
D
K
A
K
Y
I
T
G
Q
T
I
H
V
N
G
G
-----
43
PsiBlast_CBE
72.63
35%
-84
- C1 -
1VL8
2
?
A:
[22-265]
--
R
V
A
L
V
T
G
G
S
R
G
L
G
F
G
I
A
Q
G
L
A
E
A
G
C
S
V
-
V
V
A
-
S
R
N
L
E
E
A
S
E
A
A
Q
K
L
T
E
-
K
Y
G
V
E
T
M
A
F
R
C
D
V
S
N
Y
E
E
V
K
K
L
L
E
A
V
K
E
K
F
G
K
L
D
T
V
V
N
A
A
G
I
N
R
R
---
H
--
P
--
A
E
E
F
P
L
D
E
F
R
Q
V
I
E
V
N
L
F
G
T
Y
Y
V
C
R
E
A
F
S
-
L
L
R
E
S
D
N
P
S
I
I
N
I
G
S
-
L
-------
T
V
E
E
V
T-
M
P
N
I
S
A
Y
A
A
S
K
G
G
V
A
S
L
T
K
A
L
A
K
E
W
G
R
Y
G
I
R
V
N
V
I
A
P
G
W
Y
R
T
K
-
M
T
E
-----
A
V
F
S
D
P
E
K
L
D
Y
------
M
L
-
K
R
I
P
L
G
R
T
G
V
P
E
D
L
K
G
V
A
V
F
L
A
S
E
E
A
K
Y
V
T
G
Q
I
I
F
V
D
G
G
W
T
---
42
PsiBlast_CBE
72.09
35%
-84
- C1 -
1VL8
3
?
B:
[22-265]
--
R
V
A
L
V
T
G
G
S
R
G
L
G
F
G
I
A
Q
G
L
A
E
A
G
C
S
V
-
V
V
A
-
S
R
N
L
E
E
A
S
E
A
A
Q
K
L
T
E
-
K
Y
G
V
E
T
M
A
F
R
C
D
V
S
N
Y
E
E
V
K
K
L
L
E
A
V
K
E
K
F
G
K
L
D
T
V
V
N
A
A
G
I
N
R
R
---
H
--
P
--
A
E
E
F
P
L
D
E
F
R
Q
V
I
E
V
N
L
F
G
T
Y
Y
V
C
R
E
A
F
S
-
L
L
R
E
S
D
N
P
S
I
I
N
I
G
S
-
L
-------
T
V
E
E
V
T-
M
P
N
I
S
A
Y
A
A
S
K
G
G
V
A
S
L
T
K
A
L
A
K
E
W
G
R
Y
G
I
R
V
N
V
I
A
P
G
W
Y
R
T
K
-
M
T
E
-----
A
V
F
S
D
P
E
K
L
D
Y
------
M
L
-
K
R
I
P
L
G
R
T
G
V
P
E
D
L
K
G
V
A
V
F
L
A
S
E
E
A
K
Y
V
T
G
Q
I
I
F
V
D
G
G
W
T
---
4
PsiBlast_PDB
71.75
41%
-79
- C1 -
4JRO
-
?
A:
[30-271]
--
K
V
A
V
V
T
G
G
S
R
G
I
G
R
D
I
A
I
N
L
A
K
E
G
A
N
I
-
F
F
N
Y
N
G
S
P
E
A
A
E
E
T
A
K
L
V
-
A
-
E
H
G
V
E
V
E
A
M
K
A
N
V
A
I
A
E
D
V
D
A
F
F
K
Q
A
I
E
R
F
G
R
V
D
I
L
V
N
N
A
--
G
I
T
---
R
--
D
NL
L
M
R
M
K
E
D
E
W
D
D
V
I
N
I
N
L
K
G
T
F
L
C
T
K
A
V
S
R
-
T
M
M
K
Q
R
A
G
K
I
I
N
M
A
S
-
V
-------
V
G
L
I
G
--
N
A
G
Q
A
N
Y
V
A
S
K
A
G
V
I
G
L
T
K
T
T
A
R
E
L
A
P
R
G
I
N
V
N
A
V
A
P
G
F
I
T
T
D
-
M
T
D
-----
K
L
---
D
E
K
T
K
E
------
A
M
L
A
Q
I
P
L
G
A
Y
G
T
T
E
D
I
A
N
A
V
L
F
L
A
S
D
A
S
K
Y
I
T
G
Q
T
L
S
V
D
G
G
M
V
M
--
37
PsiBlast_CBE
70.09
32%
-81
- C1 -
1G0O
2
T4HR_MAGO7
D:
[30-283]
--
K
V
A
L
V
T
G
A
G
R
G
I
G
R
E
M
A
M
E
L
G
R
R
G
C
K
V
-
I
V
N
Y
A
N
S
T
E
S
A
E
E
V
V
A
A
I
-
K
-
K
N
G
S
D
A
A
C
V
K
A
N
V
G
V
V
E
D
I
V
R
M
F
E
E
A
V
K
I
F
G
K
L
D
I
V
C
S
N
S
G
V
V
S
F
---
G
--
H
--
V
K
D
V
T
P
E
E
F
D
R
V
F
T
I
N
T
R
G
Q
F
F
V
A
R
E
A
Y
K
-
H
L
E
--
I
G
G
R
L
I
L
M
G
S
-
I
T------
G
Q
A
K
A
--
V
P
K
H
A
V
Y
S
G
S
K
G
A
I
E
T
F
A
R
C
M
A
I
D
M
A
D
K
K
I
T
V
N
V
V
A
P
G
G
I
K
T
D
-
M
Y
H
AVCRE
Y
I
P
N
G
E
N
L
S
N
E
EVDEYA
A
V
-
Q
W
S
P
L
R
R
V
G
L
P
I
D
I
A
R
V
V
C
F
L
A
S
N
D
G
G
W
V
T
G
K
V
I
G
I
D
G
G
A
C
M
--
26
PsiBlast_CBE
69.80
41%
-75
- C1 -
4JRO
1
?
D:
[30-271]
--
K
V
A
V
V
T
G
G
S
R
G
I
G
R
D
I
A
I
N
L
A
K
E
G
A
N
I
-
F
F
N
Y
N
G
S
P
E
A
A
E
E
T
A
K
L
V
-
A
-
E
H
G
V
E
V
E
A
M
K
A
N
V
A
I
A
E
D
V
D
A
F
F
K
Q
A
I
E
R
F
G
R
V
D
I
L
V
N
N
A
--
G
I
T
---
R
--
D
NL
L
M
R
M
K
E
D
E
W
D
D
V
I
N
I
N
L
K
G
T
F
L
C
T
K
A
V
S
R
-
T
M
M
K
Q
R
A
G
K
I
I
N
M
A
S
-
V
-------
V
G
L
I
G
--
N
A
G
Q
A
N
Y
V
A
S
K
A
G
V
I
G
L
T
K
T
T
A
R
E
L
A
P
R
G
I
N
V
N
A
V
A
P
G
F
I
T
T
D
-
M
T
-----------
D
E
K
T
K
E
------
A
M
L
A
Q
I
P
L
G
A
Y
G
T
T
E
D
I
A
N
A
V
L
F
L
A
S
D
A
S
K
Y
I
T
G
Q
T
L
S
V
D
G
G
M
V
M
--
8
PsiBlast_PDB
69.23
38%
-89
- C1 -
4ZA2
-
?
A:
[11-249]
--
K
V
A
L
I
T
G
C
D
T
G
L
G
Q
G
M
A
I
G
L
A
Q
A
G
C
D
I
V
G
V
N
I
V
E
P
K
D
T
I
E
K
V
T
A
------
L
G
R
R
F
L
S
L
T
A
D
M
S
N
V
S
G
H
A
E
L
V
E
K
A
V
A
E
F
G
H
V
D
I
L
V
N
N
A
--
G
I
I
---
R
R
E
D
--
A
I
E
F
S
E
K
N
W
D
D
V
M
N
L
N
I
K
S
V
F
F
M
S
Q
T
V
A
R
Q
F
I
K
Q
G
K
G
G
K
I
I
N
I
A
S
-
M
L
S
F
Q
---
G
G
I
R
---
V
P
S
Y
T
A
---
S
K
S
A
V
M
G
V
T
R
L
M
A
N
E
W
A
K
H
G
I
N
V
N
A
I
A
P
G
Y
M
A
T
N
-
N
T
Q
-----
Q
L
R
A
D
E
E
R
S
K
E
------
I
L
-
D
R
I
P
A
G
R
W
G
L
P
Q
D
L
M
G
P
S
V
F
L
A
S
S
A
S
D
Y
I
N
G
Y
T
I
A
V
D
G
G
-----
32
PsiBlast_CBE
69.15
38%
-90
- C1 -
4Z9Y
1
?
B:
[11-249]
--
K
V
A
L
I
T
G
C
D
T
G
L
G
Q
G
M
A
I
G
L
A
Q
A
G
C
D
I
V
G
V
N
I
V
E
P
K
D
T
I
E
K
V
T
A
------
L
G
R
R
F
L
S
L
T
A
D
M
S
N
V
S
G
H
A
E
L
V
E
K
A
V
A
E
F
G
H
V
D
I
L
V
N
N
A
--
G
I
I
---
R
RE
D
--
A
I
E
F
S
E
K
N
W
D
D
V
M
N
L
N
I
K
S
V
F
F
M
S
Q
T
V
A
R
Q
F
I
K
Q
G
K
G
G
K
I
I
N
I
A
S
-
M
LSFQ---
G
G
I
R
---
V
P
S
Y
T
A
---
S
K
S
A
V
M
G
V
T
R
L
M
A
N
E
W
A
K
H
G
I
N
V
N
A
I
A
P
G
Y
M
A
T
N
-
N
T
Q
-----
Q
L
R
A
D
E
E
R
S
K
E
------
I
L
-
D
R
I
P
A
G
R
W
G
L
P
Q
D
L
M
G
P
S
V
F
L
A
S
S
A
S
D
Y
I
N
G
Y
T
I
A
V
D
G
G
-----
128
HHSearch
68.94
31%
-84
- C1 -
2ZAT
1
DHRS4_PIG
A:
[13-259]
E
N
K
V
A
L
V
T
A
S
T
D
G
I
G
L
A
I
A
R
R
L
A
Q
D
G
A
H
V
-
V
V
S
S
R
-
K
Q
E
N
V
D
R
T
V
A
T
L
-
Q
-
G
E
G
L
S
V
T
G
T
V
C
H
V
G
K
A
E
D
R
E
R
L
V
A
M
A
V
N
L
H
G
G
V
D
I
L
V
S
N
A
A
V
N
P
F
F--
G
--
N
--
I
I
D
A
T
E
E
V
W
D
K
I
L
H
V
N
V
K
A
T
V
L
M
T
K
A
V
V
P
-
E
M
E
K
R
G
G
G
S
V
L
I
V
S
S
-
V
-------
G
A
Y
H
P
--
F
P
N
L
G
P
Y
N
V
S
K
T
A
L
L
G
L
T
K
N
L
A
V
E
L
A
P
R
N
I
R
V
N
C
L
A
P
G
L
I
K
T
N
-
F
S
Q
-----
V
L
W
M
D
K
A
R
-
K
E
------
Y
M
K
E
S
L
R
I
R
R
L
G
N
P
E
D
C
A
G
I
V
S
F
L
C
S
E
D
A
S
Y
I
T
G
E
T
V
V
V
G
G
G
T
A
S
R
-
25
PsiBlast_CBE
68.75
42%
-77
- C1 -
3SJ7
2
?
B:
[9-249]
M
T
K
S
A
L
V
T
G
A
S
R
G
I
G
R
S
I
A
L
Q
L
A
E
E
G
Y
N
V
-
A
V
N
Y
A
G
S
K
E
K
A
E
A
V
V
E
E
I
-
K
-
A
K
G
V
D
S
F
A
I
Q
A
N
V
A
D
A
D
E
V
K
A
M
I
K
E
V
V
S
Q
F
G
S
L
D
V
L
V
N
N
A
--
G
I
T
---
R
--
D
NL
L
M
R
M
K
E
Q
E
W
D
D
V
I
D
T
N
L
K
G
V
F
N
C
I
Q
K
A
T
P
-
Q
M
L
R
Q
R
S
G
A
I
I
N
L
S
S
V
V
-------
G
A
V
G
N
P
G
Q
A
N
Y
V
A
---
T
K
A
G
V
I
G
L
T
K
S
A
A
R
E
L
A
S
R
G
I
T
V
N
A
V
A
P
G
F
I
V
S
D
--
T
D
-----
A
L
S
--
D
E
L
K
E
Q
------
M
L
-
T
Q
I
P
L
A
R
F
G
Q
D
T
D
I
A
N
T
V
A
F
L
A
S
D
K
A
K
Y
I
T
G
Q
T
I
H
V
N
G
G
-----
7
PsiBlast_PDB
68.71
38%
-89
- C1 -
4Z9Y
1
?
A:
[11-249]
--
K
V
A
L
I
T
G
C
D
T
G
L
G
Q
G
M
A
I
G
L
A
Q
A
G
C
D
I
V
G
V
N
I
V
E
P
K
D
T
I
E
K
V
T
A
------
L
G
R
R
F
L
S
L
T
A
D
M
S
N
V
S
G
H
A
E
L
V
E
K
A
V
A
E
F
G
H
V
D
I
L
V
N
N
A
--
G
I
I
---
R
R
E
D
--
A
I
E
F
S
E
K
N
W
D
D
V
M
N
L
N
I
K
S
V
F
F
M
S
Q
T
V
A
R
Q
F
I
K
Q
G
K
G
G
K
I
I
N
I
A
S
-
M
L
S
F
Q
---
G
G
I
R
---
V
P
S
Y
T
A
---
S
K
S
A
V
M
G
V
T
R
L
M
A
N
E
W
A
K
H
G
I
N
V
N
A
I
A
P
G
Y
M
A
T
N
-
N
T
Q
-----
Q
L
R
A
D
E
E
R
S
K
E
------
I
L
-
D
R
I
P
A
G
R
W
G
L
P
Q
D
L
M
G
P
S
V
F
L
A
S
S
A
S
D
Y
I
N
G
Y
T
I
A
V
D
G
G
-----
33
PsiBlast_CBE
68.69
34%
-84
- C1 -
4IBO
1
?
D:
[27-266]
--
R
T
A
L
V
T
G
S
S
R
G
L
G
R
A
M
A
E
G
L
A
V
A
G
A
R
I
-
L
I
N
G
T
D
P
S
R
V
A
Q
T
V
Q
-
E
F
-
R
-
N
V
G
H
D
A
E
A
V
A
F
D
V
T
S
E
S
E
I
I
E
A
F
A
R
L
D
E
Q
G
I
D
V
D
I
L
V
N
N
A
G
I
Q
F
R
---
K
--
P
--
M
I
E
L
E
T
A
D
W
Q
R
V
I
D
T
N
L
T
S
A
F
M
I
G
R
E
A
A
K
-
R
M
I
P
R
G
Y
G
K
I
V
N
I
G
S
-
L
-------
T
S
E
L
A
--
R
A
T
V
A
P
Y
T
V
A
K
G
G
I
K
M
L
T
R
A
M
A
A
E
W
A
Q
Y
G
I
Q
A
N
A
I
G
P
G
Y
M
L
T
D
-
M
N
Q
-----
A
L
I
D
N
P
E
F
D
A
W
------
V
K
-
A
R
T
P
A
K
R
W
G
K
P
Q
E
L
V
G
T
A
V
F
L
S
A
S
A
S
D
Y
V
N
G
Q
I
I
Y
V
D
G
G
-----
112
HHSearch
68.34
28%
-85
- C1 -
2CFC
2
HCDR_XANP2
A:
[1-249]
M
S
R
V
A
I
V
T
G
A
S
S
G
N
G
L
A
I
A
T
R
F
L
A
R
G
D
R
V
-
A
A
L
D
L
-
S
A
E
T
L
E
E
T
A
R
T
H
-
W
H
A
Y
A
D
K
V
L
R
V
R
A
D
V
A
D
E
G
D
V
N
A
A
I
A
A
T
M
E
Q
F
G
A
I
D
V
L
V
N
N
A
G
I
T
G
N
SEA
G
--
V
--
L
H
T
T
P
V
E
Q
F
D
K
V
M
A
V
N
V
R
G
I
F
L
G
C
R
A
V
L
P
-
H
M
L
L
Q
G
A
G
V
I
V
N
I
A
S
-
V
-------
A
S
L
V
A
--
F
P
G
R
S
A
Y
T
T
S
K
G
A
V
L
Q
L
T
K
S
V
A
V
D
Y
A
G
S
G
I
R
C
N
A
V
C
P
G
M
I
E
T
P
-
M
T
Q
-----
W
R
L
D
Q
P
E
L
R
D
Q
------
V
L
-
A
R
I
P
Q
K
E
I
G
T
A
A
Q
V
A
D
A
V
M
F
L
A
G
E
D
A
T
Y
V
N
G
A
A
L
V
M
D
G
A
Y
T
A
--
101
PsiBlast_CBE
65.46
32%
-83
- C1 -
4I08
6
FABG_VIBCH
A:
[13-251]
--
K
V
A
L
V
T
G
A
S
R
G
I
G
K
A
I
A
E
L
L
A
E
R
G
A
K
V
--
I
G
T
A
T
S
E
S
G
A
Q
A
I
S
D
Y
L
-
G
-
D
N
G
K
G
M
A
L
---
N
V
T
N
P
E
S
I
E
A
V
L
K
A
I
T
D
E
F
G
G
V
D
I
L
V
N
N
A
--
G
I
T
---
R
--
D
NL
L
M
R
M
K
E
E
E
W
S
D
I
M
E
T
N
L
T
S
I
F
R
L
S
K
A
V
L
R
-
G
M
M
K
K
R
Q
G
R
I
I
N
V
G
S
-
V
-------
V
G
T
M
G
--
N
A
G
Q
A
N
Y
A
A
A
K
A
G
V
I
G
F
T
K
S
M
A
R
E
V
A
S
R
G
V
T
V
N
T
V
A
P
G
F
I
E
T
D
M--
N
----------
D
E
Q
R
T
A
------
T
L
-
A
Q
V
P
A
G
R
L
G
D
P
R
E
I
A
S
A
V
A
F
L
A
S
P
E
A
A
Y
I
T
G
E
T
L
H
V
N
G
G
M
Y
M
I
-
3
PsiBlast_PDB
64.99
42%
-72
- C1 -
3SJ7
3
?
A:
[10-249]
-
T
K
S
A
L
V
T
G
A
S
R
G
I
G
R
S
I
A
L
Q
L
A
E
E
G
Y
N
V
-
A
V
N
Y
A
G
S
K
E
K
A
E
A
V
V
E
E
I
-
K
-
A
K
G
V
D
S
F
A
I
Q
A
N
V
A
D
A
D
E
V
K
A
M
I
K
E
V
V
S
Q
F
G
S
L
D
V
L
V
N
N
A
--
G
I
T
---
R
--
D
NL
L
M
R
M
K
E
Q
E
W
D
D
V
I
D
T
N
L
K
G
V
F
N
C
I
Q
K
A
T
P
-
Q
M
L
R
Q
R
S
G
A
I
I
N
L
S
S
V
V
-------
G
A
V
G
N
P
G
Q
A
N
Y
V
A
---
T
K
A
G
V
I
G
L
T
K
S
A
A
R
E
L
A
S
R
G
I
T
V
N
A
V
A
P
G
F
I
V
S
D
-
M
T
-----------
D
E
L
K
E
Q
------
M
L
-
T
Q
I
P
L
A
R
F
G
Q
D
T
D
I
A
N
T
V
A
F
L
A
S
D
K
A
K
Y
I
T
G
Q
T
I
H
V
N
G
G
-----